Page last updated: 2024-08-17

folic acid and Schizophrenia

folic acid has been researched along with Schizophrenia in 105 studies

Research

Studies (105)

TimeframeStudies, this research(%)All Research%
pre-199029 (27.62)18.7374
1990's9 (8.57)18.2507
2000's17 (16.19)29.6817
2010's37 (35.24)24.3611
2020's13 (12.38)2.80

Authors

AuthorsStudies
Chen, CH; Chen, CY; Chen, PY; Chen, YH; Chiu, CC; Huang, MC; Lin, YK; Lu, ML1
Liu, DW; Wang, D; Zhai, JX2
Kasyanov, ED; Kostina, OV; Mazo, GE; Piatoikina, AS; Rukavishnikov, GV; Semennov, IV; Verbitskaya, EV; Zhilyaeva, TV1
Bavrina, AP; Kasyanov, ED; Kostina, OV; Mazo, GE; Piatoikina, AS; Rukavishnikov, GV; Shcherbatyuk, TG; Zhilyaeva, TV; Zhukova, ES1
Clements, P; Fryar-Williams, S; Huang, Y; Strobel, J; Tucker, G1
Huang, X; Li, W; Lu, XB; Ning, YP; Qi, H; Sim, K; Ungvari, GS; Xiang, YT; Xiao, L; Zheng, W1
Abrahamsen, T; Agartz, I; Andreassen, OA; Hope, S; Hundhausen, T; Høiland, AL; Johannessen, J; Lonning, V; Malt, E; Mørkrid, L; Naerland, T; Nerhus, M; Steen, NE; Stenberg, N; Torske, T; Wedervang-Resell, K1
Fan, W; Tang, W; Wang, W; Zhang, C; Zhang, Y; Zhao, J1
Kinoshita, M; Nakataki, M; Nakayama, T; Numata, S; Ohmori, T; Tomioka, Y; Umehara, H; Watanabe, SY1
Blagonravova, AS; Mazo, GE; Zhilyaeva, TV1
Canever, L; Damázio, LS; Mastella, GA; Quevedo, JL; Valvassori, SS; Varela, R; Zugno, AI1
Cha, HY; Kim, SW; Yang, SJ1
Chaumette, B; Frajerman, A; Kebir, O; Scoriels, L1
Alves, CSV; Barcellos, AS; Budni, J; Canever, L; Citadin, S; Damázio, L; De Luca, LA; Garcez, ML; Mastella, G; Polla, JV; Quevedo, J; Zugno, AI1
Abbott, GW; Alachkar, A; Civelli, O; Hamzeh, AR; Lee, SM; Sanathara, N; Wang, L; Wang, Z; Xu, X; Yoshimura, R1
Choi, S; Kim, EJ; Kim, JM; Kim, SW; Kim, SY; Lee, HJ; Lee, JY; Lim, SY; Shin, IS; Yang, SJ; Yoon, JS1
Budni, J; Canever, L; Carvalho, G; Damázio, L; Fachim, I; Freire, TG; Gava, FF; Godói, AK; Gomes, S; Mastella, GA; Michels, C; Peterle, BR; Quevedo, J; Valvassori, SS; Zugno, AI1
Iwata, N; Kishi, T; Matsunaga, S; Nomura, I; Okuya, M; Sakuma, K1
Agartz, I; Andreassen, OA; Berg, AO; Gurholt, TP; Jørgensen, KN; Lonning, V; Melle, I; Nerhus, M; Osnes, K1
Peedicayil, J1
Akcay Ciner, O; Erol, A; Guzel, D; Mutu Pek, T; Yazici, AB; Yazici, E1
Akcay Ciner, O; Cilli, AS; Dogan, B; Erol, A; Yazici, AB; Yazici, E1
Achtyes, E; Galendez, GC; Goff, DC; Hill, M; Lamberti, JS; Macklin, EA; Raeke, LH; Roffman, JL; Silverstein, NJ; Smoller, JW1
Frydecka, D; Kiejna, A; Misiak, B; Piotrowski, P; Slezak, R1
Brown, HE; Roffman, JL1
Chen, X; Hao, Y; Li, X; Li, Y; Lü, L; Song, X; Zhang, W; Zhu, Q1
Chen, X; Fan, X; Gao, J; Kennedy, D; Li, X; Lv, L; Pang, L; Quan, M; Song, X; Zhang, J; Zhang, W1
Arroll, MA; Neil, J; Wilder, L1
Frydecka, D; Kiejna, A; Misiak, B; Ślęzak, R; Łaczmański, Ł1
Ansseau, M; Boemer, F; Bours, V; Philippe, P; Quadros, EV; Ramaekers, VT; Sequeira, JM; Thöny, B1
Chen, X; Hei, G; Lü, L; Pang, L; Song, X; Zhang, W; Zhu, Q1
Frydecka, D; Kiejna, A; Loska, O; Misiak, B; Piotrowski, P; Ślęzak, R; Szmida, E; Słoka, NK; Łaczmański, Ł1
Budni, J; Calixto, OP; Canever, L; Damázio, LS; de Oliveira, MB; Heylmann, AS; Macan, TP; Mastella, GA; Pacheco, FD; Pedro, TH; Pereira, FP; Quevedo, J; Schuck, PF; Steckert, A; Wessler, PG; Zugno, AI1
Cao, B; Liu, YQ; Lu, QB; Wang, DF; Wang, JY; Xu, MY; Yan, LL1
Chen, W; Ding, Y; He, L; Ju, M1
Bottiglieri, T; Brown, HE; Eryilmaz, H; Giegold, M; Goff, DC; Henderson, DC; Ho, NF; Manoach, DS; Petruzzi, LJ; Roffman, JL; Silverstein, NJ; Smoller, JW; Tanner, AS1
Hoffer, LJ1
Arankowsky-Sandoval, G; García-Miss, Mdel R; Gurubel-Maldonado, J; López-Canul, B; Oxté-Cabrera, A; Pérez-Mutul, J; Puga-Machado, L; Solís-Rodríguez, F1
Joshi, S; Kale, A; Kamaraju, M; Mahadik, S; Naphade, N; Pillai, A; Sapkale, S1
Ayedi, I; Bouaziz, N; El Hechmi, Z; Feki, M; Jomaa, R; Kaabechi, N; Kallel, A; Melki, W; Rafrafi, R; Sidhom, O1
Eren, E; Herken, H; Yeğin, A; Yilmaz, N1
Goff, DC; Hill, M; Jasinski, S; Macklin, EA; Raeke, L; Roffman, JL; Shannahan, K1
Bly, MJ; Brook, RD; Dalack, G; Ellingrod, VL; Evans, SJ; Gardner, KM; Grove, TB; Pop-Busui, R; Taylor, SF; Zöllner, SK1
Bouslama, A; Douki, W; Gaha, L; Mabrouk, H; Mechri, A; Najjar, MF; Omezzine, A; Younes, MK1
Brohawn, DG; Goff, DC; Macklin, EA; Nitenson, AZ; Roffman, JL; Smoller, JW1
Davis, JM; Torrey, EF1
Bly, MJ; Brook, RD; Dalack, G; Ellingrod, VL; Grove, TB; Pop-Busui, R; Taylor, SF; Zöllner, SK1
Bly, MJ; Burghardt, KJ; Ellingrod, VL; Pilsner, JR1
Davey Smith, G; Kirkbride, JB; Kresovich, JK; Kundakovic, M; Relton, CL; Susser, E1
Burghardt, KJ; Ellingrod, VL1
Mattson, MP; Shea, TB1
Blom, H; Ellenbroek, B; Eskes, T; Muntjewerff, JW; Steegers, E; van der Put, N; Zitman, F1
Arning, E; Baer, L; Bottiglieri, T; Coyle, J; Evins, AE; Freudenreich, O; Goff, DC; Henderson, DC; Shih, V1
Belmaker, RH; Friger, M; Levine, J; Stahl, Z1
O'Donnell, C; Stephens, T1
Lesch, KP; Pfuhlmann, B; Reif, A1
Blom, HJ; Muntjewerff, JW1
Babushkin, I; Belmaker, RH; Bersudsky, Y; Levine, J; Osher, Y; Ruderman, V; Sela, BA; Shumaico, O; Stahl, Z1
Baer, L; Borba, CP; Cather, C; Copeland, PM; Eden Evins, A; Freudenreich, O; Goff, DC; Henderson, DC; Nguyen, DD1
Chae, SL; Cho, SC; Han, DH; Jeon, CM; Lee, YS; Lyoo, IK; Na, C1
Keown, P; McAllister-Williams, H; Young, A1
Reynolds, E1
Allin, M; Gazi, A; Haidemenos, A; Kallai, E; Kontis, D; Lucia, B1
Smythies, JR1
Gottfries, CG; Regland, B; Smythies, JR1
Allen, RH; Brown, AS; Klonowski, E; Lindenbaum, J; Susser, E1
Chen, CH; Shih, HH; Tai, JJ; Wang-Wuu, S; Wuu, KD1
Johnson, WG1
Amado, JA; Díez-Manrique, JF; García-Unzueta, MT; Herrán, A; López-Cordovilla, JJ; Vázquez-Barquero, JL1
Czakó, M; Horváth, A; Kosztolányi, G; Melegh, B; Morava, E; Tóth, G1
Koren, G1
Chitayat, D; Cohn, T; Kapur, B; Koren, G; Reid, DM; Remington, G; Zipursky, RB1
Levi, RN; Waxman, S1
Reynolds, EH2
Carney, MW2
Blair, JA; Cooke, WT; Leeming, RJ; Melikian, V; Thien, KR1
Siva Sankar, DV1
Carney, MW; Sheffield, BF2
Brooks, SC; Disney, N; Linn, JJ1
Filip, V; Haskovec, L; Libiger, J; Müllerová, D; Nerad, J; Sikora, J1
Friedhoff, AJ; Rosengarten, H1
Köhler, GK1
Cahalane, SF; Dean, G; Hanniffy, L; O'Broin, JD; Scott, J; Stevens, F; Temperley, I1
Bradley, RJ; Linton, PH; Smythies, JR1
Finkelstein, JD; Freeman, JM; Mudd, SH1
Baldessarini, RJ1
Lee, S; Wing, YK1
Procter, A1
Bottiglieri, T; Carney, MW; Chanarin, I; Flynn, TG; Godfrey, PS; Laundy, M; Reynolds, EH; Toone, BK1
Bottiglieri, T; Carney, MW; Chanarin, I; Chary, TK; Laundy, M; Reynolds, EH; Toone, B1
Alarcon, RD; Kemp, B; Monti, JA; Morere, DA; Smythies, JR; Tolbert, LC; Walter-Ryan, WG1
Hermesh, H; Munitz, H; Shahar, A; Weizman, A1
Abou-Saleh, MT; Coppen, A1
Laduron, P1
Freeman, JM; Mudd, SH1
Callaghan, N; Cotter, P; Mitchell, R1
Gundersen, HJ1
Mehta, S; Raby, AH; Snaith, RP1

Reviews

20 review(s) available for folic acid and Schizophrenia

ArticleYear
Comparison of Serum Folate between Schizophrenic Patients and Healthy Controls in Chinese Han Adult Population: A Systematic Review and Meta-Analysis.
    Combinatorial chemistry & high throughput screening, 2023, Volume: 26, Issue:5

    Topics: Adult; Folic Acid; Humans; Schizophrenia

2023
Adjunctive folate for major mental disorders: A systematic review.
    Journal of affective disorders, 2020, 04-15, Volume: 267

    Topics: Antipsychotic Agents; Bipolar Disorder; Depressive Disorder, Major; Folic Acid; Humans; Schizophrenia

2020
Shared Biological Pathways between Antipsychotics and Omega-3 Fatty Acids: A Key Feature for Schizophrenia Preventive Treatment?
    International journal of molecular sciences, 2021, Jun-26, Volume: 22, Issue:13

    Topics: Animals; Antipsychotic Agents; Fatty Acids, Omega-3; Folic Acid; Humans; Methionine; Myelin Sheath; Schizophrenia; Synaptic Transmission

2021
Folic acid/methylfolate for the treatment of psychopathology in schizophrenia: a systematic review and meta-analysis.
    Psychopharmacology, 2018, Volume: 235, Issue:8

    Topics: Antipsychotic Agents; Depression; Double-Blind Method; Drug Therapy, Combination; Folic Acid; Humans; Psychopathology; Randomized Controlled Trials as Topic; Schizophrenia; Schizophrenic Psychology; Tetrahydrofolates; Treatment Outcome

2018
Vitamin supplementation in the treatment of schizophrenia.
    CNS drugs, 2014, Volume: 28, Issue:7

    Topics: Avitaminosis; Dietary Supplements; Folic Acid; Humans; Schizophrenia; Vitamin B 12; Vitamin D; Vitamins

2014
Nutritional interventions for the adjunctive treatment of schizophrenia: a brief review.
    Nutrition journal, 2014, Sep-16, Volume: 13

    Topics: Acetylcysteine; Antipsychotic Agents; Ascorbic Acid; Databases, Factual; Diet, Gluten-Free; Dietary Supplements; Fatty Acids, Unsaturated; Folic Acid; Glutamates; Humans; Melatonin; Oxidative Stress; Randomized Controlled Trials as Topic; Schizophrenia; Thioctic Acid; Vitamin B Complex; Vitamin D; Vitamin E

2014
Serum folate levels in schizophrenia: A meta-analysis.
    Psychiatry research, 2016, Jan-30, Volume: 235

    Topics: Adult; Age Factors; Aged; Ethnicity; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Middle Aged; Reproducibility of Results; Risk Factors; Schizophrenia; Sex Factors; Time Factors

2016
Lower folate levels in schizophrenia: A meta-analysis.
    Psychiatry research, 2016, Nov-30, Volume: 245

    Topics: Case-Control Studies; Cohort Studies; Cross-Cultural Comparison; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Humans; Reference Values; Schizophrenia; Schizophrenic Psychology

2016
Association of Folate Level in Blood with the Risk of Schizophrenia.
    Combinatorial chemistry & high throughput screening, 2017, Volume: 20, Issue:2

    Topics: Biomarkers; Disease Susceptibility; Folic Acid; Humans; Racial Groups; Risk Factors; Schizophrenia

2017
Vitamin therapy in schizophrenia.
    The Israel journal of psychiatry and related sciences, 2008, Volume: 45, Issue:1

    Topics: Ascorbic Acid; Avitaminosis; Folic Acid; Humans; Niacin; Schizophrenia; Vitamins

2008
Adjunct treatments for schizophrenia and bipolar disorder: what to try when you are out of ideas.
    Clinical schizophrenia & related psychoses, 2012, Volume: 5, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aspirin; Benzothiazoles; Bipolar Disorder; Celecoxib; Chemotherapy, Adjuvant; Cyclooxygenase 2 Inhibitors; Dopamine Agonists; Estrogens; Fatty Acids, Omega-3; Folic Acid; Humans; Mianserin; Minocycline; Mirtazapine; Pramipexole; Pregnenolone; Pyrazoles; Randomized Controlled Trials as Topic; Schizophrenia; Sulfonamides; Treatment Outcome; Vitamin B Complex

2012
Detection of metabolic syndrome in schizophrenia and implications for antipsychotic therapy : is there a role for folate?
    Molecular diagnosis & therapy, 2013, Volume: 17, Issue:1

    Topics: Antipsychotic Agents; Cardiovascular Diseases; Catechol O-Methyltransferase; Dietary Supplements; Epigenomics; Folic Acid; Humans; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Pharmacogenetics; Risk Factors; Schizophrenia

2013
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
    Trends in neurosciences, 2003, Volume: 26, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke

2003
Aberrant folate status in schizophrenic patients: what is the evidence?
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:7

    Topics: Folic Acid; Folic Acid Deficiency; Humans; MEDLINE; Schizophrenia

2005
Disturbances of one-carbon metabolism in neuropsychiatric disorders: a review.
    Biological psychiatry, 1997, Jan-15, Volume: 41, Issue:2

    Topics: Carbon; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Neurocognitive Disorders; S-Adenosylmethionine; Schizophrenia

1997
A review of recent studies of the biosynthesis and excretion of hallucinogens formed by methylation of neurotransmitters or related substances.
    Schizophrenia bulletin, 1976, Volume: 2, Issue:1

    Topics: Alcohol Oxidoreductases; Bufotenin; Carbolines; Dimethoxyphenylethylamine; Dopamine; Ethylamines; Folic Acid; Hallucinogens; Humans; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Norepinephrine; S-Adenosylmethionine; Schizophrenia; Serotonin; Tryptamines

1976
Neuropharmacology of S-adenosyl methionine.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:3

    Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Dementia; Depressive Disorder; Epilepsy; Folic Acid; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Methionine Adenosyltransferase; Methylation; Nervous System Diseases; Phospholipids; Proteins; Rats; S-Adenosylmethionine; Schizophrenia; Synapses; Synaptic Transmission

1986
The biology of folate in depression: implications for nutritional hypotheses of the psychoses.
    Journal of psychiatric research, 1986, Volume: 20, Issue:2

    Topics: Anorexia Nervosa; Biogenic Amines; Brain; Depressive Disorder; Diet; Folic Acid; Folic Acid Deficiency; Homocystinuria; Humans; Models, Theoretical; Pellagra; Pterins; S-Adenosylmethionine; Schizophrenia; Tryptophan; Vitamin B 12 Deficiency

1986
Epilepsy and schizophrenia: relationship and biochemistry.
    Lancet (London, England), 1968, Feb-24, Volume: 1, Issue:7539

    Topics: Anemia, Macrocytic; Anticonvulsants; Electroconvulsive Therapy; Electroencephalography; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Mental Disorders; Methionine; Phenethylamines; Phenothiazines; Schizophrenia; Vitamin B 12

1968
The relationship of serum folic acid and vitamin B 12 levels to psychosis in epilepsy.
    Irish journal of medical science, 1969, Volume: 8, Issue:10

    Topics: Adult; Age Factors; Aged; Anemia, Hypochromic; Epilepsy; Female; Folic Acid; Humans; Male; Middle Aged; Psychotic Disorders; Schizophrenia; Vitamin B 12

1969

Trials

7 trial(s) available for folic acid and Schizophrenia

ArticleYear
Randomized multicenter investigation of folate plus vitamin B12 supplementation in schizophrenia.
    JAMA psychiatry, 2013, Volume: 70, Issue:5

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Glutamate Carboxypeptidase II; Humans; Male; Middle Aged; Schizophrenia; Treatment Outcome; Vitamin B 12; Young Adult

2013
Biochemical, physiological and clinical effects of l-methylfolate in schizophrenia: a randomized controlled trial.
    Molecular psychiatry, 2018, Volume: 23, Issue:2

    Topics: Adult; Antipsychotic Agents; Cognition; Double-Blind Method; Female; Folic Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Tetrahydrofolates; Treatment Outcome

2018
Folate supplementation in schizophrenia: a possible role for MTHFR genotype.
    Schizophrenia research, 2011, Volume: 127, Issue:1-3

    Topics: Adolescent; Adult; Aged; Cognition Disorders; Double-Blind Method; Female; Folic Acid; Genome-Wide Association Study; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Outpatients; Polymorphism, Genetic; Psychiatric Status Rating Scales; Schizophrenia; Vitamin B Complex; Young Adult

2011
Homocysteine-reducing strategies improve symptoms in chronic schizophrenic patients with hyperhomocysteinemia.
    Biological psychiatry, 2006, Aug-01, Volume: 60, Issue:3

    Topics: Adult; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Pyridoxine; Schizophrenia; Schizophrenic Psychology; Time Factors; Vitamin B 12; Vitamin B Complex

2006
Proceedings: The effect of folic acid in chronic schizophrenics.
    Activitas nervosa superior, 1975, Volume: 17, Issue:4

    Topics: Adult; Clinical Trials as Topic; Female; Folic Acid; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology

1975
Enhancement of recovery from psychiatric illness by methylfolate.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: Depressive Disorder; Double-Blind Method; Folic Acid; Folic Acid Deficiency; Humans; Methotrexate; Schizophrenia; Schizophrenic Psychology

1991
Enhancement of recovery from psychiatric illness by methylfolate.
    Lancet (London, England), 1990, Aug-18, Volume: 336, Issue:8712

    Topics: Adult; Aged; Depressive Disorder; Double-Blind Method; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Schizophrenia; Vitamin B 12

1990

Other Studies

78 other study(ies) available for folic acid and Schizophrenia

ArticleYear
Associations of Genetic Variants of Methylenetetrahydrofolate Reductase and Serum Folate Levels with Metabolic Parameters in Patients with Schizophrenia.
    International journal of environmental research and public health, 2021, 10-28, Volume: 18, Issue:21

    Topics: Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Prospective Studies; Schizophrenia

2021
Tetrahydrobiopterin deficiency in schizophrenia: Biochemical and clinical aspects.
    Journal of psychiatric research, 2022, Volume: 153

    Topics: C-Reactive Protein; Case-Control Studies; Folic Acid; Homocysteine; Humans; Phenylketonurias; Schizophrenia; Vitamin B 12

2022
Pterin metabolism, inflammation and oxidative stress biochemical markers in schizophrenia: Factor analysis and assessment of clinical symptoms associations.
    Progress in neuro-psychopharmacology & biological psychiatry, 2023, 12-20, Volume: 127

    Topics: Biochemical Phenomena; Biomarkers; Folic Acid; Humans; Inflammation; Oxidative Stress; Pterins; Schizophrenia

2023
Molecular Mechanism Biomarkers Predict Diagnosis in Schizophrenia and Schizoaffective Psychosis, with Implications for Treatment.
    International journal of molecular sciences, 2023, Oct-31, Volume: 24, Issue:21

    Topics: Biomarkers; Catecholamines; Folic Acid; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Psychotic Disorders; Riboflavin; Schizophrenia; Vitamins

2023
Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia: A comparison among participants between 2 and 53 years.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:6

    Topics: Adolescent; Adult; Case-Control Studies; Child; Child, Preschool; Dietary Supplements; Female; Folic Acid; Hemoglobins; Humans; Leukocytes; Male; Middle Aged; Neurodevelopmental Disorders; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2020
Homocysteine, but not MTHFR gene polymorphism, influences depressive symptoms in patients with schizophrenia.
    Journal of affective disorders, 2020, 07-01, Volume: 272

    Topics: Depression; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Schizophrenia

2020
Association between serum folate levels and schizophrenia based on sex.
    Psychiatry and clinical neurosciences, 2020, Volume: 74, Issue:9

    Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Japan; Male; Middle Aged; Schizophrenia; Sex Factors; Vitamin B 6

2020
[The effect of various forms of folates on cognitive functions in patients with chronic schizophrenia].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2020, Volume: 120, Issue:9

    Topics: Cognition; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Schizophrenia

2020
Effects of maternal folic acid supplementation on nuclear methyltransferase activity of adult rats subjected to an animal model of schizophrenia.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2021, Volume: 81, Issue:5

    Topics: Animals; Cell Nucleus; Diet; Dietary Supplements; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Ketamine; Male; Methyltransferases; Pregnancy; Rats; Rats, Wistar; Schizophrenia; Schizophrenic Psychology

2021
Higher Dietary Inflammation in Patients with Schizophrenia: A Case-Control Study in Korea.
    Nutrients, 2021, Jun-13, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Ascorbic Acid; Case-Control Studies; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Energy Intake; Female; Folic Acid; Humans; Inflammation; Male; Micronutrients; Middle Aged; Niacin; Republic of Korea; Schizophrenia; Vitamins; Young Adult

2021
The Evaluation of Folic Acid-Deficient or Folic Acid-Supplemented Diet in the Gestational Phase of Female Rats and in Their Adult Offspring Subjected to an Animal Model of Schizophrenia.
    Molecular neurobiology, 2018, Volume: 55, Issue:3

    Topics: Animals; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Folic Acid Deficiency; Inflammation Mediators; Ketamine; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Schizophrenia; Vitamin B Complex

2018
Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits.
    Molecular psychiatry, 2018, Volume: 23, Issue:2

    Topics: Animals; Antipsychotic Agents; Basic Helix-Loop-Helix Transcription Factors; CA1 Region, Hippocampal; Clozapine; Developmental Disabilities; Disease Models, Animal; Female; Folic Acid; Haloperidol; Humans; Male; Methionine; Mice; Neurogenesis; Neuronal Plasticity; One-Carbon Group Transferases; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Schizophrenia; Stereotyped Behavior; Tetrahydrofolates

2018
Low dietary intake of n-3 fatty acids, niacin, folate, and vitamin C in Korean patients with schizophrenia and the development of dietary guidelines for schizophrenia.
    Nutrition research (New York, N.Y.), 2017, Volume: 45

    Topics: Adult; Ascorbic Acid; Diet; Fatty Acids, Omega-3; Feeding Behavior; Female; Folic Acid; Humans; Male; Middle Aged; Minerals; Niacin; Nutrition Policy; Nutritional Status; Obesity; Overweight; Schizophrenia; Vitamins

2017
Changes in behavioural parameters, oxidative stress and neurotrophins in the brain of adult offspring induced to an animal model of schizophrenia: The effects of FA deficient or FA supplemented diet during the neurodevelopmental phase.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 08-30, Volume: 86

    Topics: Animals; Behavior, Animal; Brain; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Folic Acid Deficiency; Ketamine; Male; Nerve Growth Factors; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Wistar; Schizophrenia; Schizophrenic Psychology

2018
Vitamin D, Folate and the Intracranial Volume in Schizophrenia and Bipolar Disorder and Healthy Controls.
    Scientific reports, 2018, Jul-17, Volume: 8, Issue:1

    Topics: Adult; Bipolar Disorder; Brain; Case-Control Studies; Female; Folic Acid; Humans; Linear Models; Magnetic Resonance Imaging; Male; Schizophrenia; Vitamin D; Young Adult

2018
Folic acid and its congeners in the treatment of schizophrenia.
    Psychopharmacology, 2019, Volume: 236, Issue:4

    Topics: Folic Acid; Humans; Psychopathology; Schizophrenia

2019
Klotho, vitamin D and homocysteine levels during acute episode and remission periods in schizophrenia patients.
    Nordic journal of psychiatry, 2019, Volume: 73, Issue:3

    Topics: Acute Disease; Adult; Aged; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Glucuronidase; Homocysteine; Humans; Klotho Proteins; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Vitamin B 12; Vitamin D; Young Adult

2019
Comparison of vitamin B12, vitamin D and folic acid blood levels in patients with schizophrenia, drug addiction and controls.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 65

    Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Incidence; Male; Middle Aged; Prevalence; Schizophrenia; Substance-Related Disorders; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D; Vitamin D Deficiency

2019
Elevated homocysteine level in first-episode schizophrenia patients--the relevance of family history of schizophrenia and lifetime diagnosis of cannabis abuse.
    Metabolic brain disease, 2014, Volume: 29, Issue:3

    Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Lipoproteins, HDL; Male; Marijuana Abuse; Schizophrenia; Vitamin B 12; Young Adult

2014
[Correlation between serum levels of homocysteine and folate and cognitive dysfunction in first-episode schizophrenics].
    Zhonghua yi xue za zhi, 2014, Apr-08, Volume: 94, Issue:13

    Topics: Adolescent; Adult; Case-Control Studies; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Schizophrenia; Vitamin B 12; Young Adult

2014
Serum levels of BDNF, folate and homocysteine: in relation to hippocampal volume and psychopathology in drug naïve, first episode schizophrenia.
    Schizophrenia research, 2014, Volume: 159, Issue:1

    Topics: Adolescent; Adult; Blood Chemical Analysis; Brain-Derived Neurotrophic Factor; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Hippocampus; Homocysteine; Humans; Image Processing, Computer-Assisted; Immunoassay; Male; Organ Size; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Young Adult

2014
Effects of second-generation antipsychotics on selected markers of one-carbon metabolism and metabolic syndrome components in first-episode schizophrenia patients.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:12

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Mass Index; Carbon; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Lipid Metabolism; Male; Metabolic Syndrome; Olanzapine; Risperidone; Schizophrenia; Sex Factors; Triglycerides; Vitamin B 12; Young Adult

2014
Folinic acid treatment for schizophrenia associated with folate receptor autoantibodies.
    Molecular genetics and metabolism, 2014, Volume: 113, Issue:4

    Topics: Adolescent; Adult; Autoantibodies; Biopterins; Child; Female; Folate Receptor 1; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Middle Aged; Schizophrenia; Young Adult

2014
[Association of serum folic acid and homocysteine levels and 5, 10-methylenetetrahydrofolate reductase gene polymorphism with schizophrenia].
    Zhonghua yi xue za zhi, 2014, Oct-14, Volume: 94, Issue:37

    Topics: Alleles; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Schizophrenia

2014
Metabolic dysregulation in first-episode schizophrenia patients with respect to genetic variation in one-carbon metabolism.
    Psychiatry research, 2016, Apr-30, Volume: 238

    Topics: Adult; Betaine-Homocysteine S-Methyltransferase; Blood Glucose; Carbon; Case-Control Studies; Dyslipidemias; Fasting; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Male; Metabolic Syndrome; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Minor Histocompatibility Antigens; One-Carbon Group Transferases; Polymorphism, Genetic; Prevalence; Psychotic Disorders; Schizophrenia; Triglycerides; Vitamin B 12; Young Adult

2016
Effect of folic acid on oxidative stress and behavioral changes in the animal model of schizophrenia induced by ketamine.
    Journal of psychiatric research, 2016, Volume: 81

    Topics: Animals; Attention Deficit and Disruptive Behavior Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Folic Acid; Interpersonal Relations; Ketamine; Lipid Metabolism; Locomotion; Male; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Schizophrenia; Superoxide Dismutase; Time Factors; Vitamin B Complex

2016
Folate, homocysteine, interleukin-6, and tumor necrosis factor alfa levels, but not the methylenetetrahydrofolate reductase C677T polymorphism, are risk factors for schizophrenia.
    Journal of psychiatric research, 2010, Volume: 44, Issue:7

    Topics: Adult; Analysis of Variance; Erythrocytes; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Interleukin-6; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Predictive Value of Tests; Risk Factors; Schizophrenia; Tumor Necrosis Factor-alpha; Young Adult

2010
Reduced folic acid, vitamin B12 and docosahexaenoic acid and increased homocysteine and cortisol in never-medicated schizophrenia patients: implications for altered one-carbon metabolism.
    Psychiatry research, 2010, Jan-30, Volume: 175, Issue:1-2

    Topics: Adolescent; Adult; Case-Control Studies; Docosahexaenoic Acids; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hydrocortisone; Male; Psychiatric Status Rating Scales; Schizophrenia; Vitamin B 12; Young Adult

2010
Plasma homocysteine in schizophrenia: determinants and clinical correlations in Tunisian patients free from antipsychotics.
    Psychiatry research, 2010, Aug-30, Volume: 179, Issue:1

    Topics: Adult; Dementia; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Psychiatric Status Rating Scales; Psychometrics; Retrospective Studies; Schizophrenia; Statistics as Topic; Tunisia; Vitamin B 12

2010
Serum total homocystein, folate and vitamin B12 levels and their correlation with antipsychotic drug doses in adult male patients with chronic schizophrenia.
    Clinical laboratory, 2010, Volume: 56, Issue:11-12

    Topics: Adolescent; Adult; Antipsychotic Agents; Case-Control Studies; Chlorpromazine; Chronic Disease; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Luminescent Measurements; Male; Middle Aged; Schizophrenia; Statistics, Nonparametric; Vitamin B 12

2010
Dietary, lifestyle and pharmacogenetic factors associated with arteriole endothelial-dependent vasodilatation in schizophrenia patients treated with atypical antipsychotics (AAPs).
    Schizophrenia research, 2011, Volume: 130, Issue:1-3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Arterioles; Catechol O-Methyltransferase; Cross-Sectional Studies; Endothelium-Dependent Relaxing Factors; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Life Style; Male; Manometry; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Regression Analysis; Schizophrenia; Schizophrenic Psychology; Young Adult

2011
[Hyperhomocysteinemia and schizophrenia: case control study].
    L'Encephale, 2011, Volume: 37, Issue:4

    Topics: Adult; Case-Control Studies; Chronic Disease; Comorbidity; Cross-Sectional Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reference Values; Schizophrenia; Schizophrenic Psychology; Statistics as Topic; Vitamin B 12

2011
Genetic variation throughout the folate metabolic pathway influences negative symptom severity in schizophrenia.
    Schizophrenia bulletin, 2013, Volume: 39, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Catechol O-Methyltransferase; Cohort Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Glutamate Carboxypeptidase II; Humans; Linear Models; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index

2013
Risk factors associated with metabolic syndrome in bipolar and schizophrenia subjects treated with antipsychotics: the role of folate pharmacogenetics.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:2

    Topics: Adult; Age Factors; Antipsychotic Agents; Bipolar Disorder; Catechol O-Methyltransferase; Cross-Sectional Studies; Female; Folic Acid; Genetic Variation; Homocysteine; Humans; Life Style; Male; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Risk Factors; Schizophrenia; Smoking

2012
DNA methylation in schizophrenia subjects: gender and MTHFR 677C/T genotype differences.
    Epigenomics, 2012, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Chlorpromazine; DNA Methylation; DNA Mutational Analysis; Female; Folic Acid; Genotype; Humans; Long Interspersed Nucleotide Elements; Male; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Molecular Typing; Polymorphism, Single Nucleotide; Schizophrenia; Sex Factors

2012
Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?
    Epigenomics, 2012, Volume: 4, Issue:3

    Topics: Brain; Cell Adhesion Molecules, Neuronal; CpG Islands; DNA Methylation; Epigenesis, Genetic; Epigenomics; Extracellular Matrix Proteins; Female; Folic Acid; Humans; Mendelian Randomization Analysis; Methylenetetrahydrofolate Reductase (NADPH2); Nerve Tissue Proteins; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Reelin Protein; Risk Factors; Schizophrenia; Serine Endopeptidases

2012
Homocysteine metabolism and B-vitamins in schizophrenic patients: low plasma folate as a possible independent risk factor for schizophrenia.
    Psychiatry research, 2003, Nov-01, Volume: 121, Issue:1

    Topics: Adult; Base Pairing; DNA Mutational Analysis; Erythrocytes; Female; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Assessment; Schizophrenia; Schizophrenic Psychology; Vitamin B 12; Vitamin B 6

2003
Folate, homocysteine, and negative symptoms in schizophrenia.
    The American journal of psychiatry, 2004, Volume: 161, Issue:9

    Topics: Adult; Ambulatory Care; Basal Ganglia Diseases; Diet; Female; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Smoking; Vitamin B 12

2004
Nutritional and life style determinants of plasma homocysteine in schizophrenia patients.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Blood Chemical Analysis; Female; Folic Acid; Homocysteine; Humans; Life Style; Male; Middle Aged; Nutritional Status; Schizophrenia; Vitamin B 12

2005
The significance of homocysteine levels in schizophrenia.
    The American journal of psychiatry, 2005, Volume: 162, Issue:7

    Topics: Age Factors; Chromatography, High Pressure Liquid; Female; Fluorescence Polarization Immunoassay; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Research Design; Schizophrenia; Sex Factors

2005
Homocysteinemia as well as methylenetetrahydrofolate reductase polymorphism are associated with affective psychoses.
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Chi-Square Distribution; Dementia; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Schizophrenia; Vitamin B 12

2005
Homocysteine levels and glucose metabolism in non-obese, non-diabetic chronic schizophrenia.
    Acta psychiatrica Scandinavica, 2006, Volume: 113, Issue:2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Blood Pressure; Chronic Disease; Clozapine; Community Mental Health Centers; Female; Folic Acid; Homeostasis; Homocysteine; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Nutrition Assessment; Olanzapine; Prediabetic State; Psychotic Disorders; Reference Values; Risk Factors; Risperidone; Schizophrenia; Sex Factors; Statistics as Topic; Waist-Hip Ratio

2006
Serum homocysteine, folate level and methylenetetrahydrofolate reductase 677, 1298 gene polymorphism in Korean schizophrenic patients.
    Neuroreport, 2006, May-15, Volume: 17, Issue:7

    Topics: Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Korea; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors; Schizophrenia

2006
A case of pancytopenia.
    Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:5

    Topics: Adult; Anticonvulsants; Folic Acid; Humans; Male; Pancytopenia; Schizophrenia; Schizophrenic Psychology; Valproic Acid; Vitamin B 12

2006
Folate and ageing.
    Lancet (London, England), 2007, May-12, Volume: 369, Issue:9573

    Topics: Aged; Aging; Cognition; Depression; Folic Acid; Folic Acid Deficiency; Hematinics; Humans; Schizophrenia

2007
Plasma homocysteine, folate and B12 in chronic schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Aug-15, Volume: 31, Issue:6

    Topics: Adult; Age Factors; Aged; Analysis of Variance; Chi-Square Distribution; Chronic Disease; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Schizophrenia; Sex Factors; Vitamin B 12

2007
The transmethylation and one-carbon cycle hypotheses of schizophrenia.
    Psychological medicine, 1983, Volume: 13, Issue:4

    Topics: Brain; Catecholamines; Folic Acid; Humans; Kinetics; Methionine; Methylation; S-Adenosylmethionine; Schizophrenia

1983
Folate-responsive homocystinuria and "schizophrenia'.
    Nutrition reviews, 1982, Volume: 40, Issue:8

    Topics: Adolescent; Female; Folic Acid; Homocystinuria; Humans; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Models, Biological; Oxidoreductases; Schizophrenia

1982
Schizophrenia and impaired homocysteine metabolism: a possible association.
    Biological psychiatry, 1998, Jul-15, Volume: 44, Issue:2

    Topics: Adult; Animals; Case-Control Studies; Comorbidity; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Pilot Projects; Schizophrenia

1998
Chromosomal fragile site expression in lymphocytes from patients with schizophrenia.
    Human genetics, 1998, Volume: 103, Issue:6

    Topics: Adult; Asian People; Case-Control Studies; Cells, Cultured; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 9; Cohort Studies; Distamycins; Female; Folic Acid; Humans; Lymphocytes; Male; Schizophrenia; Taiwan

1998
DNA polymorphism-diet-cofactor-development hypothesis and the gene-teratogen model for schizophrenia and other developmental disorders.
    American journal of medical genetics, 1999, Aug-20, Volume: 88, Issue:4

    Topics: Alleles; Brain; Diet; Female; Folic Acid; Folic Acid Deficiency; Genetic Linkage; Genotype; Humans; Male; Models, Genetic; Pedigree; Phenotype; Phenylketonuria, Maternal; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Pyridoxine; Schizophrenia; Teratogens; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency

1999
Folate levels in psychiatric outpatients.
    Psychiatry and clinical neurosciences, 1999, Volume: 53, Issue:4

    Topics: Adult; Biomarkers; Depressive Disorder; Female; Folic Acid; Humans; Male; Schizophrenia; Severity of Illness Index

1999
[Vascular diseases, spina bifida and schizophrenia in a single family associated with the heterozygote mutation of the heat-sensitive variant of methylenetetrahydrofolate reductase].
    Orvosi hetilap, 2001, Jul-08, Volume: 142, Issue:27

    Topics: Adult; Female; Folic Acid; Heterozygote; Hot Temperature; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pedigree; Pulmonary Embolism; Schizophrenia; Spinal Dysraphism; Thrombosis; Vascular Diseases

2001
Maternal obesity and risk of neural tube defects.
    Canadian family physician Medecin de famille canadien, 2001, Volume: 47

    Topics: Antipsychotic Agents; Benzodiazepines; Female; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Obesity; Olanzapine; Pirenzepine; Pregnancy; Pregnancy Complications; Risk Factors; Schizophrenia

2001
Use of atypical antipsychotics during pregnancy and the risk of neural tube defects in infants.
    The American journal of psychiatry, 2002, Volume: 159, Issue:1

    Topics: Adult; Antipsychotic Agents; Body Mass Index; Female; Folic Acid; Humans; Infant, Newborn; Male; Neural Tube Defects; Obesity; Pregnancy; Pregnancy Complications; Risk Factors; Schizophrenia

2002
Editorial: Folate-responsive schizophrenia.
    Lancet (London, England), 1975, Jun-07, Volume: 1, Issue:7919

    Topics: Adolescent; Alcohol Oxidoreductases; Female; Folic Acid; Folic Acid Deficiency; Humans; Schizophrenia

1975
Schizophrenia, epilepsy, cancer, methionine, and folate metabolism. Pathogenesis of schizophrenia.
    Lancet (London, England), 1975, Jul-05, Volume: 2, Issue:7923

    Topics: Anticonvulsants; Epilepsy; Folic Acid; Folic Acid Antagonists; Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; Schizophrenia

1975
Letter: Folate-responsive schizophrenia.
    Lancet (London, England), 1975, Jul-26, Volume: 2, Issue:7926

    Topics: Brain; Folic Acid; Folic Acid Deficiency; Humans; Mental Disorders; Schizophrenia

1975
Letter: Folate-responsive schizophrenia.
    Lancet (London, England), 1975, Aug-09, Volume: 2, Issue:7928

    Topics: Folic Acid; Folic Acid Deficiency; Humans; Schizophrenia

1975
Serum folates in man.
    Journal of clinical pathology, 1977, Volume: 30, Issue:5

    Topics: Anemia, Pernicious; Arthritis, Rheumatoid; Biological Assay; Celiac Disease; Enterococcus faecalis; Folic Acid; Formyltetrahydrofolates; Humans; Lacticaseibacillus casei; Leukemia; Pediococcus; Schizophrenia; Tetrahydrofolates

1977
Plasma levels of folates, riboflavin, vitamin B6, and ascorbate in severely disturbed children.
    Journal of autism and developmental disorders, 1979, Volume: 9, Issue:1

    Topics: Adolescent; Affective Symptoms; Ascorbic Acid; Autistic Disorder; Child; Child Behavior Disorders; Child, Preschool; Folic Acid; Humans; Intellectual Disability; Male; Orthomolecular Therapy; Psychotic Disorders; Pyridoxine; Riboflavin; Schizophrenia

1979
Serum folic acid and B12 in 272 psychiatric in-patients.
    Psychological medicine, 1978, Volume: 8, Issue:1

    Topics: Adult; Aged; Alcoholism; Depression; England; Folic Acid; Folic Acid Deficiency; Hospitals, Psychiatric; Humans; Mental Disorders; Middle Aged; Neurocognitive Disorders; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency

1978
Serotonin, folic acid, and uric acid metabolism in the diagnosis of neuropsychiatric disorders.
    Biological psychiatry, 1978, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Bipolar Disorder; Brain; Carbolines; Female; Folic Acid; Hallucinations; Humans; Male; Mental Disorders; Middle Aged; Neurotic Disorders; Personality Disorders; Schizophrenia; Schizophrenia, Catatonic; Schizophrenia, Childhood; Serotonin; Suicide; Uric Acid

1978
[Psychoses in epilepsy--classification and EEG-studies (author's transl)].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1975, Volume: 43, Issue:3

    Topics: Acute Disease; Anticonvulsants; Chronic Disease; Electroencephalography; Epilepsy; Folic Acid; Humans; Neurocognitive Disorders; Personality Disorders; Psychoses, Substance-Induced; Schizophrenia; Time Factors

1975
Schizophrenia and coeliac disease.
    Irish medical journal, 1975, Nov-22, Volume: 68, Issue:21

    Topics: Biopsy; Celiac Disease; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestines; Male; Schizophrenia; United Kingdom

1975
Meeting report: Biochemical aspects of schizophrenia. Alabama, April 1975.
    Psychoneuroendocrinology, 1975, Volume: 1, Issue:2

    Topics: Acute Disease; Blood Platelets; Chronic Disease; Dopamine; Folic Acid; gamma-Aminobutyric Acid; Hallucinogens; Humans; Mesencephalon; Methionine; Monoamine Oxidase; Prolactin; Receptors, Dopamine; Schizophrenia; Serotonin; T-Lymphocytes

1975
Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity.
    The New England journal of medicine, 1975, Mar-06, Volume: 292, Issue:10

    Topics: Adolescent; Alcohol Oxidoreductases; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Schizophrenia; Tetrahydrofolates; Vitamin B 12

1975
Editorial: Metabolic hypotheses in schizophrenia.
    The New England journal of medicine, 1975, Mar-06, Volume: 292, Issue:10

    Topics: Folic Acid; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Psychotic Disorders; Schizophrenia

1975
Methylfolate and psychiatric illness.
    The British journal of psychiatry : the journal of mental science, 1992, Volume: 160

    Topics: Depressive Disorder; Folic Acid; Folic Acid Antagonists; Humans; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1992
Red cell folate concentrations in psychiatric patients.
    Journal of affective disorders, 1990, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcoholism; Bipolar Disorder; Depressive Disorder; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Mental Disorders; Middle Aged; Schizophrenia; Vitamin B 12

1990
One-carbon metabolism disturbances in affective disorders. A preliminary report.
    Journal of affective disorders, 1985, Volume: 9, Issue:3

    Topics: Bipolar Disorder; Depressive Disorder; Erythrocytes; Folic Acid; Humans; Kinetics; Methionine Adenosyltransferase; Phosphatidylcholines; S-Adenosylmethionine; Schizophrenia; Transferases

1985
Vitamin B12 and folic acid serum levels in obsessive compulsive disorder.
    Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:1

    Topics: Folic Acid; Humans; Obsessive-Compulsive Disorder; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency

1988
Megavitamin and orthomolecular therapy in psychiatry.
    Nutrition reviews, 1974, Volume: 32, Issue:0

    Topics: Aged; Alcoholism; Ascorbic Acid; Avitaminosis; Child; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Folic Acid; Humans; Mental Disorders; NAD; Nicotinic Acids; Psychiatry; Pyridoxine; Schizophrenia; Substance-Related Disorders; Vitamin B 12; Vitamins

1974
A new hypothesis on the origin of schizophrenia.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Brain; Folic Acid; Humans; Liposomes; Methylation; Schizophrenia; Tetrahydrofolates

1974
N-5,10-methylenetetrahydrofolate reductase deficiency and schizophrenia: a working hypothesis.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Adolescent; Dopamine; Female; Fibroblasts; Folic Acid; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Methyltransferases; Oxidoreductases; Schizophrenia; Tetrahydrofolates

1974
Serum folate in psychiatric patients under long-term treatment with tricyclic neuroleptic drugs.
    Acta psychiatrica Scandinavica, 1969, Volume: 45, Issue:2

    Topics: Adult; Aged; Female; Folic Acid; Humans; Middle Aged; Schizophrenia; Tranquilizing Agents; Vitamin B 12

1969
Serum folate and vitamin B12 in epileptics with and without mental illness.
    The British journal of psychiatry : the journal of mental science, 1970, Volume: 116, Issue:531

    Topics: Anticonvulsants; Epilepsy; Folic Acid; Humans; Mental Disorders; Psychotic Disorders; Schizophrenia; Vitamin B 12

1970
Associations of subnormal serum folate and vitamin B12 values and effects of replacement therapy.
    The Journal of nervous and mental disease, 1970, Volume: 150, Issue:5

    Topics: Adult; Aged; Antidepressive Agents; Barbiturates; Chronic Disease; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Hematologic Diseases; Humans; Male; Middle Aged; Neurocognitive Disorders; Phenothiazines; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency

1970