folic acid has been researched along with Osteosarcoma in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (21.74) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 7 (30.43) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, F; Chen, X; Jing, D; Liu, J; Pu, F; Shao, Z; Wu, W; Xiao, H; Zhang, Z | 1 |
| Dong, S; Gao, Q; Gao, Y; He, X; Li, N; Li, X; Wang, S; Wang, Z; Zhang, B | 1 |
| Jia, ML; Liu, SY; Liu, W; Yang, H; Zeng, XF; Zhang, W; Zhu, WT | 1 |
| Chen, W; Kang, Y; Lou, Y; Xu, W | 1 |
| Chen, J; Huang, X; Qing, X; Shao, Z; Wu, W; Yang, W; Zhong, B | 1 |
| Coulembier, O; De Winter, J; Dozio, SM; Liénard, R; Mineo, PG; Montesi, M; Panseri, S; Piperno, A; Scala, A; Vento, F | 1 |
| Deng, X; Hu, H; Liang, Z; Liu, W; Shao, Z; Song, Q; Wang, B; Wang, S; Xing, X; Yang, W; Zhang, Y; Zhong, B; Zhou, Z; Zhu, J | 1 |
| Cavallaro, G; Giammona, G; Li Volsi, A; Licciardi, M; Scialabba, C; Vetri, V | 1 |
| Ai, JW; Liu, B; Liu, WD | 1 |
| Huang, LL; Li, D; Pang, JD; Sun, K; Wang, F; Wang, LT; Wang, R; Zhang, LM | 1 |
| Dolžan, V; Goričar, K; Jazbec, J; Kovač, V; Lamovec, J; Zakotnik, B | 1 |
| Gorlick, R; Healey, JH; Hoang, BH; Qin, J; Yang, R | 1 |
| Marrodán, L; Patiño-García, A; San-Julián, M; Sierrasesúmaga, L; Zalacaín, M | 1 |
| Andersen, AM; Hall, KS; Holmboe, L; Mørkrid, L; Slørdal, L | 1 |
| BERTINO, JR; HELLMAN, S; IANNOTTI, AT | 1 |
| Choy, JH; Han, OJ; Jeong, J; Jung, JS; Kang, YK; Oh, JM; Park, M | 1 |
| Flintoff, WF; Gorlick, R; Sadlish, H; Williams, FM; Yang, R | 1 |
| Chou, A; Gorlick, R; Healey, JH; Hoang, B; Huvos, AG; Kolb, EA; Meyers, PA; Qin, J; Sowers, R; Yang, R | 1 |
| Diddens, H; Jackson, RC; Niethammer, D | 2 |
| Dennebaum, R; Fischer, J; Preiss, J; Przybylski, M | 1 |
| Amyx, H; Boytos, CM; Duch, DS; Ferone, R; Smith, GK; Wilson, HR | 1 |
| Janka, G | 1 |
23 other study(ies) available for folic acid and Osteosarcoma
| Article | Year |
|---|---|
Quercetin encapsulated in folic acid-modified liposomes is therapeutic against osteosarcoma by non-covalent binding to the JH2 domain of JAK2 Via the JAK2-STAT3-PDL1.
Topics: Adolescent; B7-H1 Antigen; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Folic Acid; Humans; Janus Kinase 2; Liposomes; Osteosarcoma; Quercetin; STAT3 Transcription Factor | 2022 |
MiRNA-520a-3p combined with folic acid conjugated Fe
Topics: Adolescent; Bone Neoplasms; Cell Line, Tumor; Folic Acid; Humans; Magnetic Resonance Imaging; MicroRNAs; Nanoparticles; Osteosarcoma; Photothermal Therapy | 2023 |
Resveratrol Loaded by Folate-Modified Liposomes Inhibits Osteosarcoma Growth and Lung Metastasis via Regulating JAK2/STAT3 Pathway.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Folic Acid; Humans; Janus Kinase 2; Lipopolysaccharides; Liposomes; Lung Neoplasms; Mice; Osteosarcoma; Resveratrol; STAT3 Transcription Factor | 2023 |
Folic acid decorated metal-organic frameworks loaded with doxorubicin for tumor-targeted chemotherapy of osteosarcoma.
Topics: Antineoplastic Agents; Bone Neoplasms; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Metal-Organic Frameworks; Nanoparticles; Osteosarcoma | 2020 |
Delivery of MutT homolog 1 inhibitor by functionalized graphene oxide nanoparticles for enhanced chemo-photodynamic therapy triggers cell death in osteosarcoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; DNA Repair Enzymes; Doxorubicin; Drug Therapy; Endoplasmic Reticulum Stress; Female; Folic Acid; Graphite; Humans; Indocyanine Green; Infrared Rays; Mice, Inbred BALB C; Nanoparticles; Osteosarcoma; Phosphoric Monoester Hydrolases; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Pyrimidines; Xenograft Model Antitumor Assays | 2020 |
Design of naturally inspired jellyfish-shaped cyclopolylactides to manage osteosarcoma cancer stem cells fate.
Topics: Bone Neoplasms; Cell Line, Tumor; Folic Acid; Humans; Nanoparticles; Neoplastic Stem Cells; Osteosarcoma; Polyethylene Glycols | 2020 |
Amplification of oxidative stress with lycorine and gold-based nanocomposites for synergistic cascade cancer therapy.
Topics: Amaryllidaceae Alkaloids; Animals; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum Stress; Folic Acid; Gold; Humans; Mice; Microscopy, Fluorescence; Mitochondria; Nanocomposites; Neoplasms; Osteosarcoma; Oxidative Stress; Phenanthridines; Reactive Oxygen Species; Silicon Dioxide | 2021 |
Near-Infrared Light Responsive Folate Targeted Gold Nanorods for Combined Photothermal-Chemotherapy of Osteosarcoma.
Topics: Cell Line, Tumor; Folic Acid; Gold; Humans; Nanotubes; Osteosarcoma | 2017 |
Folic acid-tagged titanium dioxide nanoparticles for enhanced anticancer effect in osteosarcoma cells.
Topics: Cell Survival; Folic Acid; Humans; Nanoparticles; Osteosarcoma; Titanium | 2017 |
Nanoscale polysaccharide derivative as an AEG-1 siRNA carrier for effective osteosarcoma therapy.
Topics: Animals; Bone Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Chitosan; Dendrimers; Folic Acid; Gene Silencing; Genetic Therapy; Humans; Male; Matrix Metalloproteinase 2; Membrane Proteins; Mice, Nude; Nanoparticles; Osteosarcoma; Polylysine; RNA-Binding Proteins; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2018 |
Influence of the folate pathway and transporter polymorphisms on methotrexate treatment outcome in osteosarcoma.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Neoplasms; Child; Female; Folic Acid; Humans; Liver-Specific Organic Anion Transporter 1; Male; Methotrexate; Organic Anion Transporters; Osteosarcoma; Polymorphism, Single Nucleotide; Survival Analysis; Treatment Outcome; Young Adult | 2014 |
Polymorphisms and methylation of the reduced folate carrier in osteosarcoma.
Topics: Adolescent; Adult; Aged; Bone Neoplasms; Child; Child, Preschool; DNA Methylation; Female; Folic Acid; Humans; Male; Membrane Transport Proteins; Middle Aged; Osteosarcoma; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Reduced Folate Carrier Protein; RNA, Messenger; Transcription, Genetic | 2008 |
Methotrexate in pediatric osteosarcoma: response and toxicity in relation to genetic polymorphisms and dihydrofolate reductase and reduced folate carrier 1 expression.
Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; Carrier Proteins; Case-Control Studies; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gastrointestinal Diseases; Genotype; Hematologic Diseases; Humans; Kidney Diseases; Male; Methotrexate; Osteosarcoma; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Cell Surface; RNA, Messenger; Tetrahydrofolate Dehydrogenase | 2009 |
High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients.
Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Area Under Curve; Bone Neoplasms; Child; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Male; Methotrexate; Middle Aged; Osteosarcoma; Reduced Folate Carrier Protein; Sex Factors; Treatment Outcome; Young Adult | 2012 |
DETERMINATIONS OF THE LEVELS OF SERUM FOLATE IN PATIENTS WITH CARCINOMA OF THE HEAD AND NECK TREATED WITH METHOTREXATE.
Topics: Blood Chemical Analysis; Carcinoma, Squamous Cell; Folic Acid; Humans; Methotrexate; Nasopharyngeal Neoplasms; Neoplasms; Nose Neoplasms; Osteosarcoma; Pathology; Pharmacology; Pharyngeal Neoplasms; Sarcoma; Tongue Neoplasms | 1964 |
Layered double hydroxide as an efficient drug reservoir for folate derivatives.
Topics: Absorption; Antineoplastic Agents; Biocompatible Materials; Cell Division; Cell Line, Tumor; Drug Delivery Systems; Drug Evaluation; Drug Stability; Fibroblasts; Folic Acid; Humans; Hydroxides; Leucovorin; Macromolecular Substances; Materials Testing; Methotrexate; Molecular Conformation; Osteosarcoma; Pharmaceutical Vehicles | 2004 |
Functional analysis of altered reduced folate carrier sequence changes identified in osteosarcomas.
Topics: Amino Acid Sequence; Animals; Biotin; Biotinylation; Blotting, Western; Cell Line, Tumor; Cell Membrane; DNA; DNA, Complementary; Drug Resistance, Neoplasm; Epitopes; Folic Acid; Humans; Kinetics; Membrane Transport Proteins; Microscopy, Confocal; Molecular Sequence Data; Osteosarcoma; Phenotype; Protein Structure, Tertiary; Recombinant Fusion Proteins; Reduced Folate Carrier Protein; RNA, Messenger; Transfection | 2004 |
The folate receptor alpha is frequently overexpressed in osteosarcoma samples and plays a role in the uptake of the physiologic substrate 5-methyltetrahydrofolate.
Topics: Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Carrier Proteins; Cell Line, Tumor; Drug Resistance, Neoplasm; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Osteosarcoma; Receptors, Cell Surface; RNA, Messenger; Tetrahydrofolates; Xenograft Model Antitumor Assays | 2007 |
Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
Topics: Antineoplastic Agents; Biological Transport; Burkitt Lymphoma; Cell Line; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leukemia, Lymphoid; Lymphoma; Methotrexate; Osteosarcoma; Pyrimethamine; Quinazolines; Structure-Activity Relationship; T-Lymphocytes; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1983 |
Resistance of human tumor cell lines to antifolates.
Topics: B-Lymphocytes; Biological Transport; Cell Line; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Karyotyping; Methotrexate; Osteosarcoma; Pyrimethamine; Quinazolines; T-Lymphocytes; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1984 |
Identification and quantitation of methotrexate and methotrexate metabolites in clinical high-dose therapy by high pressure liquid chromatography and field desorption mass spectrometry.
Topics: Adult; Chromatography, High Pressure Liquid; Folic Acid; Humans; Immunoenzyme Techniques; Male; Mass Spectrometry; Methotrexate; Osteosarcoma | 1982 |
Enhanced antitumor activity for the thymidylate synthase inhibitor 1843U89 through decreased host toxicity with oral folic acid.
Topics: Animals; Body Weight; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Folic Acid; Humans; Indoles; Intestinal Diseases; Isoindoles; Leucovorin; Mice; Neoplasms, Experimental; Osteosarcoma; Quinazolines; Thymidylate Synthase; Tumor Cells, Cultured | 1995 |
[Malignant juvenile bone tumors].
Topics: Adolescent; Adult; Aged; Amputation, Surgical; Bone Neoplasms; Child; Diagnosis, Differential; Doxorubicin; Drug Therapy, Combination; Eosinophilic Granuloma; Female; Folic Acid; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteomyelitis; Osteosarcoma; Sarcoma, Ewing | 1978 |