Page last updated: 2024-08-17

folic acid and Non-alcoholic Fatty Liver Disease

folic acid has been researched along with Non-alcoholic Fatty Liver Disease in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's18 (54.55)24.3611
2020's15 (45.45)2.80

Authors

AuthorsStudies
Al-Ghamdi, A; El-Garawani, IM; El-Nabi, SEH; Hathout, HMR; Ismail, AHA; Kamel, MA; Salman, M; Ullah, S1
Abdul Ghani, SAB; Arul, K; Bee, GGB; Cheah, CC; Chow, PKH; Cook, SA; Lim, TR; Pei, HJ; Sandireddy, R; Shekeran, SG; Singh, BK; Singh, MK; Sinha, RA; Suzuki, A; Tikno, K; Tripathi, M; Wang, J; Widjaja, A; Wong, KA; Xiao, RP; Yen, PM; Zhang, X; Zhou, J1
Avigan, MI; Beland, FA; da Costa, GG; de Conti, A; Nagumalli, SK; Pogribny, IP; Rusyn, I; Tryndyak, VP; Willett, RA1
Chen, J; Dan, L; Larsson, SC; Li, X; Sun, Y; Xie, Y; Yuan, S1
Cao, H; Chen, X; Duan, H; Jiang, Y; Shen, J; Song, C; Tian, F; Wan, H; Yu, G1
Chen, B; Chen, X; Lu, J; Shen, L; Xu, Q1
Liu, Z; Shen, S; Wen, Y; Xu, C; Zeng, Y1
Cao, JC; Chen, CJ; Deng, Z; Liu, FR; Sun, YY; Zhang, B1
Gao, Y; Liu, W; Sun, X; Tan, Y; Wang, T; Wu, X; Xu, Q; Xu, S; Yuan, M; Zhao, Z; Zheng, B1
Chen, HK; Guo, XG; Hu, YQ; Li, XJ; Liao, WZ; Luo, J1
Chen, Y; Luo, L; Qin, H; Tong, S; Xiang, L1
Chmurzynska, A; Martínez, JA; Milagro, FI; Muzsik, A; Radziejewska, A1
Kamel, MA; Youssry, S1
Fan, JG; Gong, ZZ; Pan, Q; Sun, C; Xin, FZ; Zhang, RN; Zhao, ZH1
Doskey, CM; Fader, KA; Fling, RR; Nault, R; Zacharewski, TR1
Classen, HG; Eckert, GP; Egert, S; Frank, J; Golombek, J; Kisters, K; Lorkowski, S; Obeid, R; Pettersen, JA; Podszun, MC; Stirban, OA; Venturelli, S; Wallert, M1
O, K; Sid, V; Siow, YL1
Bian, H; Chang, XX; Gao, X; Hu, XQ; Lin, HD; Xia, MF; Yan, HM; Zhang, LS; Zhu, XP1
Adiels, M; Bäckhed, F; Bergentall, M; Bergh, PO; Bergström, G; Bjornson, E; Borén, J; Granér, M; Hakkarainen, A; Lee, S; Lundbom, N; Mancina, RM; Mardinoglu, A; Marschall, HU; Matikainen, N; Nielsen, J; Perkins, R; Piening, BD; Pietiläinen, KH; Räsänen, SM; Romeo, S; Snyder, M; Söderlund, S; Ståhlman, M; Taskinen, MR; Uhlén, M; Williams, KJ; Wu, H; Zhang, C1
Adawi, M; Amital, H; Bragazzi, NL; Mahamid, M; Mahroum, N; Shalaata, K; Watad, A; Yavne, Y1
de Mello, VD; Hanhineva, K; Ling, C; Männistö, V; Perfilyev, A; Pihlajamäki, J; Vaittinen, M; Walle, P1
Ali, MA; Bakir, MB; Kamel, MA; Khalifa, EA; Refaat, R; Salama, MA1
Cherrington, NJ; Hardwick, RN; Lake, AD; Leamon, CP; Low, PS1
Beland, FA; de Conti, A; James, SJ; Kutanzi, K; Latendresse, JR; Melnyk, S; Montgomery, B; Muskhelishvili, L; Pogribna, M; Pogribny, IP; Rusyn, I; Tryndyak, V1
Bezerra, LC; D'Almeida, V; de Carvalho, SC; de Oliveira, CP; Gomes, AV; Muniz, MT; Pereira, LM; Silva, KA; Siqueira, ER; Siqueira, MD1
Horváth, T; Littvay, L; Métneki, J; Tárnoki, ÁD; Tárnoki, DL1
Ahn, SB; Bae, HS; Cho, YJ; Cho, YK; Han, JM; Jang, EC; Jo, AN; Jun, DW; Kim, SW; Lee, SM; Suk, KT; Yoon, JH1
Cherrington, NJ; Coen, M; Goedken, MJ; Hardwick, RN; Holmes, E; Jin, Z; Kyriakides, M1
Best, A; Caudill, MA; Christensen, KE; Deng, L; Greene, ND; Leung, KY; Lévesque, N; Malysheva, OV; Mikael, LG; Rozen, R; Wu, Q1
Bozkurt, A; Kasapoglu, B; Kosar, A; Turkay, C; Yalcin, KS1
Beland, FA; Fuscoe, JC; Han, T; Pogribny, IP; Ross, SA; Tryndyak, VP1
Campion, J; Cordero, P; Martínez, JA; Milagro, FI1
Deretzi, G; Katsiki, E; Kountouras, J; Patsiaoura, K; Polyzos, SA; Slavakis, A; Tsiaousi, E; Zafeiriadou, E; Zavos, C1

Reviews

5 review(s) available for folic acid and Non-alcoholic Fatty Liver Disease

ArticleYear
Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation.
    The American journal of clinical nutrition, 2022, 12-19, Volume: 116, Issue:6

    Topics: Folic Acid; Genome-Wide Association Study; Homocysteine; Humans; Mendelian Randomization Analysis; Non-alcoholic Fatty Liver Disease; Polymorphism, Single Nucleotide

2022
One-Carbon Metabolism and Nonalcoholic Fatty Liver Disease: The Crosstalk between Nutrients, Microbiota, and Genetics.
    Lifestyle genomics, 2020, Volume: 13, Issue:2

    Topics: Animals; Betaine; Carbon; Choline; Disease Progression; Female; Folic Acid; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lipid Metabolism; Liver; Methionine; Microbiota; Models, Genetic; Non-alcoholic Fatty Liver Disease; Nutrients; Polymorphism, Single Nucleotide; Pregnancy; Prenatal Exposure Delayed Effects; Risk

2020
The role of biofactors in the prevention and treatment of age-related diseases.
    BioFactors (Oxford, England), 2021, Volume: 47, Issue:4

    Topics: Aged; Cardiovascular Diseases; Dementia; Diabetes Mellitus; Dietary Fiber; Dietary Supplements; Epigenesis, Genetic; Fatty Acids, Omega-3; Folic Acid; Humans; Neoplasms; Non-alcoholic Fatty Liver Disease; Thiamine; Thioctic Acid; Vitamin D; Vitamin E

2021
Role of folate in nonalcoholic fatty liver disease.
    Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:10

    Topics: Animals; Energy Metabolism; Folic Acid; Folic Acid Deficiency; Humans; Inflammation Mediators; Liver; Non-alcoholic Fatty Liver Disease; Oxidative Stress

2017
[Hungarian twin studies: results of four decades].
    Orvosi hetilap, 2013, Oct-06, Volume: 154, Issue:40

    Topics: Alcohol Drinking; Body Composition; Carotid Intima-Media Thickness; Congenital Abnormalities; Contraceptives, Oral; Diseases in Twins; Fatty Liver; Female; Folic Acid; Gene-Environment Interaction; Genetic Diseases, Inborn; Humans; Hungary; Lactose Intolerance; Mendelian Randomization Analysis; Non-alcoholic Fatty Liver Disease; Pregnancy; Pregnancy, Twin; Psychosexual Development; Registries; Smoking; Twin Studies as Topic; Vascular Stiffness

2013

Other Studies

28 other study(ies) available for folic acid and Non-alcoholic Fatty Liver Disease

ArticleYear
The regulation of HBP1, SIRT1, and SREBP-1c genes and the related microRNAs in non-alcoholic fatty liver rats: The association with the folic acid anti-steatosis.
    PloS one, 2022, Volume: 17, Issue:4

    Topics: Animals; Diet, High-Fat; Folic Acid; Liver; MicroRNAs; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Sirtuin 1; Sterol Regulatory Element Binding Protein 1

2022
Vitamin B
    Journal of hepatology, 2022, Volume: 77, Issue:5

    Topics: Animals; Fatty Acids; Fibrosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Qa-SNARE Proteins; Vitamin B 12; Vitamins

2022
Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice.
    The Journal of nutritional biochemistry, 2022, Volume: 109

    Topics: Animals; Choline; Collaborative Cross Mice; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Female; Folic Acid; Lipidomics; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Sucrose

2022
Associations of serum folate and vitamin C levels with metabolic dysfunction-associated fatty liver disease in US adults: A nationwide cross-sectional study.
    Frontiers in public health, 2022, Volume: 10

    Topics: Adult; Ascorbic Acid; Cross-Sectional Studies; Folic Acid; Humans; Non-alcoholic Fatty Liver Disease; Nutrition Surveys; Vitamin B 12; Vitamin B 12 Deficiency

2022
The association between serum folate and ultrasound - defined hepatic steatosis.
    Annals of medicine, 2023, Volume: 55, Issue:1

    Topics: Elasticity Imaging Techniques; Fatty Liver; Folic Acid; Humans; Liver; Male; Non-alcoholic Fatty Liver Disease; Nutrition Surveys; Prospective Studies; ROC Curve

2023
Association between folate and non-alcoholic fatty liver disease among US adults: a nationwide cross-sectional analysis.
    Chinese medical journal, 2023, 01-20, Volume: 136, Issue:2

    Topics: Adult; Cross-Sectional Studies; Folic Acid; Humans; Non-alcoholic Fatty Liver Disease; Risk Factors

2023
Folate intake and non-alcoholic fatty liver disease in US adults.
    Asia Pacific journal of clinical nutrition, 2023, Volume: 32, Issue:1

    Topics: Adult; Diet; Female; Folic Acid; Humans; Non-alcoholic Fatty Liver Disease; Nutrition Surveys; Risk Factors

2023
Mitochondrial folate metabolism-mediated α-linolenic acid exhaustion masks liver fibrosis resolution.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:7

    Topics: alpha-Linolenic Acid; Animals; Feedback, Physiological; Folic Acid; Folic Acid Deficiency; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Mice; Mitochondria; Non-alcoholic Fatty Liver Disease; Signal Transduction; Transforming Growth Factor beta1

2023
Serum folate associated with nonalcoholic fatty liver disease and advanced hepatic fibrosis.
    Scientific reports, 2023, 08-09, Volume: 13, Issue:1

    Topics: Adult; Cross-Sectional Studies; Folic Acid; Humans; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Nutrition Surveys; Prospective Studies

2023
Correlation of Nonalcoholic Fatty Liver Disease with Dietary Folate and Serum Folate in U.S. Adults: Cross-Sectional Analyses from National Health and Nutrition Examination Survey 2009-2018.
    Metabolic syndrome and related disorders, 2023, Volume: 21, Issue:7

    Topics: Adult; Cross-Sectional Studies; Diet; Female; Folic Acid; Humans; Male; Non-alcoholic Fatty Liver Disease; Nutrition Surveys

2023
Effect of folate supplementation on immunological and autophagy markers in experimental nonalcoholic fatty liver disease.
    European cytokine network, 2019, Dec-01, Volume: 30, Issue:4

    Topics: Animals; Autophagy; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Immunologic; Folic Acid; Gene Expression Regulation; Interleukin-22; Interleukin-8; Interleukins; Lipid Metabolism; Liver; Male; Microtubule-Associated Proteins; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2019
Folic acid attenuates high-fat diet-induced steatohepatitis
    World journal of gastroenterology, 2020, May-14, Volume: 26, Issue:18

    Topics: Animals; Cell Line, Tumor; Diet, High-Fat; Disease Models, Animal; DNA, Bacterial; Feces; Folic Acid; Gastrointestinal Microbiome; Humans; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; PPAR alpha; Rats; RNA, Ribosomal, 16S; RNA, Small Interfering; Sirtuin 1; Up-Regulation

2020
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice.
    Scientific reports, 2020, 09-09, Volume: 10, Issue:1

    Topics: Adenosylhomocysteinase; Animals; Betaine-Homocysteine S-Methyltransferase; Carbon; Disease Progression; Fibrosis; Folic Acid; Glycine N-Methyltransferase; Liver; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Polychlorinated Dibenzodioxins

2020
Serum folic acid levels are associated with the presence and severity of liver steatosis in Chinese adults.
    Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:5

    Topics: Adult; Aged; Asian People; Biopsy; China; DNA Methylation; Female; Folic Acid; Humans; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Proton Magnetic Resonance Spectroscopy; ROC Curve

2018
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.
    Cell metabolism, 2018, 03-06, Volume: 27, Issue:3

    Topics: Cohort Studies; Diet, Carbohydrate-Restricted; Female; Folic Acid; Gastrointestinal Microbiome; Humans; Lipid Metabolism; Male; Middle Aged; Non-alcoholic Fatty Liver Disease

2018
Folate and B12 Levels Correlate with Histological Severity in NASH Patients.
    Nutrients, 2018, Apr-02, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Aged; Biopsy; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Severity of Illness Index; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2018
Liver DNA methylation of FADS2 associates with FADS2 genotype.
    Clinical epigenetics, 2019, 01-17, Volume: 11, Issue:1

    Topics: Adult; CpG Islands; Delta-5 Fatty Acid Desaturase; DNA Methylation; Epigenesis, Genetic; Fatty Acid Desaturases; Female; Folic Acid; Gene Expression Profiling; Genetic Association Studies; Genotype; Humans; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Sequence Analysis, RNA; Up-Regulation

2019
Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease.
    European journal of pharmacology, 2019, Mar-15, Volume: 847

    Topics: Animals; Betaine; Carbon; Choline; Diet, High-Fat; Dietary Supplements; DNA Methylation; Folic Acid; Glutathione; Homocysteine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; S-Adenosylmethionine

2019
Folate receptor-beta expression as a diagnostic target in human & rodent nonalcoholic steatohepatitis.
    Toxicology and applied pharmacology, 2019, 04-01, Volume: 368

    Topics: Animals; Biomarkers; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Folate Receptor 2; Folic Acid; Humans; Liver; Macrophages; Male; Methionine; Mice, Inbred C57BL; Molecular Imaging; Non-alcoholic Fatty Liver Disease; Organotechnetium Compounds; Predictive Value of Tests; Radiopharmaceuticals; Rats, Sprague-Dawley; Tomography, Emission-Computed, Single-Photon

2019
Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:6

    Topics: Animals; Carbon; Choline; Choline Deficiency; Cystathionine beta-Synthase; Disease Models, Animal; Down-Regulation; Fatty Liver; Folic Acid; Folic Acid Deficiency; Humans; Liver; Male; Methionine Adenosyltransferase; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred Strains; Non-alcoholic Fatty Liver Disease; Species Specificity

2013
Plasmatic higher levels of homocysteine in non-alcoholic fatty liver disease (NAFLD).
    Nutrition journal, 2013, Apr-02, Volume: 12

    Topics: Adult; Biomarkers; Brazil; Cholesterol; Chronic Disease; Fatty Liver; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Leukocytes, Mononuclear; Liver; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Non-alcoholic Fatty Liver Disease; Polymorphism, Genetic; Triglycerides; Vitamin B 12

2013
Associations between intakes of individual nutrients or whole food groups and non-alcoholic fatty liver disease among Korean adults.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:6

    Topics: Adult; Aged; Ascorbic Acid; Asian People; Case-Control Studies; Diet; Fatty Acids, Omega-3; Female; Folic Acid; Food; Humans; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Nuts; Republic of Korea; Risk; Seeds; Vegetables; Vitamin K; Young Adult

2014
Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 142, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Energy Metabolism; Folic Acid; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methotrexate; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats, Sprague-Dawley; Tissue Distribution

2014
High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:3

    Topics: Animals; Dietary Supplements; Enzyme Inhibitors; Folic Acid; Gene Expression Regulation; Heterozygote; Homocystinuria; Lipid Metabolism; Lipogenesis; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Mice, Mutant Strains; Muscle Spasticity; Mutation; Non-alcoholic Fatty Liver Disease; Organ Size; Psychotic Disorders; Specific Pathogen-Free Organisms

2015
MTHFR 677C/T and 1298A/C mutations and non-alcoholic fatty liver disease.
    Clinical medicine (London, England), 2015, Volume: 15, Issue:3

    Topics: Adult; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Non-alcoholic Fatty Liver Disease; Vitamin B 12

2015
Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice.
    BMC genomics, 2016, Apr-22, Volume: 17

    Topics: Animals; Choline; CpG Islands; Cytosine; Diet; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Folic Acid; Histones; Liver; Mice; Mice, Inbred A; Mice, Inbred Strains; Non-alcoholic Fatty Liver Disease

2016
Dietary supplementation with methyl donor groups could prevent nonalcoholic fatty liver.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:6

    Topics: Animals; Betaine; Choline; Dietary Fats; Dietary Sucrose; Dietary Supplements; Disease Models, Animal; Fatty Liver; Folic Acid; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Vitamin B 12

2011
Serum vitamin B12 and folate levels in patients with non-alcoholic fatty liver disease.
    International journal of food sciences and nutrition, 2012, Volume: 63, Issue:6

    Topics: Cross-Sectional Studies; Fatty Liver; Female; Folic Acid; Humans; Logistic Models; Male; Menopause; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Vitamin B 12

2012