Page last updated: 2024-08-17

folic acid and Neutropenia

folic acid has been researched along with Neutropenia in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19905 (18.52)18.7374
1990's3 (11.11)18.2507
2000's12 (44.44)29.6817
2010's5 (18.52)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
de Rouw, N; Derijks, HJ; Piet, B; Ter Heine, R; van den Heuvel, MM1
Lyu, H; Solomon, DH; Vanni, KMM1
Burger, RA; Coleman, RL; Depasquale, SE; Gabrail, NY; Gersh, RH; Ghamande, SA; Gilbert, L; Harb, WA; Konstantinopoulos, PA; Kutarska, E; Leamon, CP; Lovejoy, CD; Messmann, RA; Morgenstern, DE; Naumann, RW; Nowara, E; Penson, RT; Sausville, EA; Symanowski, JT; Teneriello, MG1
Hosomi, Y; Iguchi, M; Nagamata, M; Nakahara, Y; Okamoto, H; Okamura, T; Okuma, Y; Shibuya, M; Shimokawa, T; Sunami, K; Takagi, Y; Yomota, M1
Chohnabayashi, N; Gotoh, K; Jinta, T; Kitamura, A; Koyama, K; Nishimura, N; Ohde, S; Okafuji, K; Takayama, S; Tomishima, Y; Tsuda, Y; Yagi, N1
Hidaka, M; Hidaka, T; Kawakita, T; Migita, K; Mori, S; Tsuda, H; Ueki, Y; Yoshitama, T1
Aghajanian, CA; Fury, M; Gerst, S; Goss, TL; Hensley, ML; Konner, J; Larkin, J; Orlando, M; Sabbatini, P; Tai, DF1
Latz, JE; Miller, MA; Nakagawa, K; Schneck, KL; Takimoto, CH1
Arpin, D; Biron, E; Cadranel, J; Duruisseaux, M; Guérin, JC; Pérol, M1
Igawa, S; Katono, K; Maki, S; Masuda, N; Otani, S; Ryuge, S; Sasaki, J; Sato, Y; Takakura, A; Wada, M1
Blatter, J; Burris, H; Gatzemeier, U; Keppler, U; Kindler, HL; Manegold, C; Rusthoven, JJ; Scagliotti, GV; Shin, DM; Symanowski, JT; Vasconcelles, MJ1
Bajetta, E; Becerra, C; Buzzoni, R; Celio, L; Ferrari, L; Ilardi, C; John, W; Longarini, R; Marchianò, A; Martinetti, A1
DUBOIS-FERRIERE, H1
Kleppa, KE; Stuen, S1
Branda, RF; Brooks, EM; Chen, Z; Muss, H; Naud, SJ1
BRAIER, L1
Ghosh, A; Johnson, RD; Karlsson, MO; Latz, JE; Rusthoven, JJ1
Asadi-Pooya, AA; Ghetmiri, E1
Baker, SD; Chaudhary, AK; Chaudhuri, T; Goetz, A; Hammond, LA; Johnson, RD; Latz, JE; Mita, AC; Molpus, K; Patnaik, A; Rowinsky, EK; Sandler, A; Simms, L; Sweeney, CJ; Takimoto, CH; Tolcher, AW; Villalona-Calero, M1
Adachi, S; Fukuoka, M; Kudoh, S; Latz, JE; Matsui, K; Nakagawa, K; Negoro, S; Yamamoto, N1
Biasini, A; Biasini, G; Dalla Villa, A; Marchisio, P; Principi, N1
Cao, G; Falguera, M; Perez-Mur, J; Puig, T1
Brennan, J; Hageboutros, A; Hudes, GR; LaCreta, FP; McAleer, C; Newman, EM; O'Dwyer, PJ; Ozols, RF; Rogatko, A1
Burris, H; Goetz, A; Hohneker, JA; Johnson, TR; Lampkin, T; Rowinsky, EK; Sailstad, J; Schwartz, G; Smetzer, L; Von Hoff, DD1
Bunch, SE; Cullen, JM; Easley, JR1
Green, ST; Nathwani, D1
Lennard, L; Lilleyman, JS; Maddocks, JL1

Reviews

2 review(s) available for folic acid and Neutropenia

ArticleYear
Mechanisms, Management and Prevention of Pemetrexed-Related Toxicity.
    Drug safety, 2021, Volume: 44, Issue:12

    Topics: Folic Acid; Glutamates; Guanine; Humans; Leucovorin; Neutropenia; Pemetrexed

2021
Cytopenias among patients with rheumatic diseases using methotrexate: a meta-analysis of randomized controlled clinical trials.
    Rheumatology (Oxford, England), 2020, 04-01, Volume: 59, Issue:4

    Topics: Anemia; Antirheumatic Agents; Arthritis, Rheumatoid; Folic Acid; Humans; Leucovorin; Leukopenia; Methotrexate; Neutropenia; Pancytopenia; Randomized Controlled Trials as Topic; Rheumatic Diseases; Severity of Illness Index; Thrombocytopenia; Vitamin B Complex

2020

Trials

11 trial(s) available for folic acid and Neutropenia

ArticleYear
PRECEDENT: a randomized phase II trial comparing vintafolide (EC145) and pegylated liposomal doxorubicin (PLD) in combination versus PLD alone in patients with platinum-resistant ovarian cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Dec-10, Volume: 31, Issue:35

    Topics: Administration, Intravenous; Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Drug Resistance, Neoplasm; Fatigue; Female; Folic Acid; Humans; Kaplan-Meier Estimate; Middle Aged; Nausea; Neutropenia; Oligopeptides; Ovarian Neoplasms; Platinum; Polyethylene Glycols; Treatment Outcome; Vinca Alkaloids

2013
A prospective study of shortened vitamin supplementation prior to cisplatin-pemetrexed therapy for non-small cell lung cancer.
    The oncologist, 2014, Volume: 19, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Pemetrexed; Prospective Studies; Treatment Outcome; Vitamin B 12

2014
A phase I trial of pemetrexed plus gemcitabine given biweekly with B-vitamin support in solid tumor malignancies or advanced epithelial ovarian cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Oct-01, Volume: 14, Issue:19

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Deoxycytidine; Dietary Supplements; Drug Administration Schedule; Female; Folic Acid; Gemcitabine; Glutamates; Guanine; Humans; Maximum Tolerated Dose; Neoplasms; Neutropenia; Ovarian Neoplasms; Pemetrexed; Treatment Outcome; Vitamin B Complex

2008
Phase II study of pemetrexed with and without folic acid and vitamin B12 as front-line therapy in malignant pleural mesothelioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Apr-15, Volume: 21, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Drug Administration Schedule; Female; Folic Acid; Folic Acid Antagonists; Follow-Up Studies; Glutamates; Guanine; Hematinics; Humans; Leukopenia; Male; Mesothelioma; Middle Aged; Neutropenia; Pemetrexed; Pleural Neoplasms; Survival Analysis; Treatment Outcome

2003
Phase II study of pemetrexed disodium (Alimta) administered with oral folic acid in patients with advanced gastric cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:10

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Female; Folic Acid; Glutamates; Guanine; Hematinics; Humans; Infusions, Intravenous; Male; Middle Aged; Neutropenia; Pemetrexed; Stomach Neoplasms; Treatment Outcome

2003
Folic acid supplementation reduces the development of some blood cell abnormalities in children receiving carbamazepine.
    Epilepsy & behavior : E&B, 2006, Volume: 8, Issue:1

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Dietary Supplements; Female; Folic Acid; Hematinics; Humans; Leukocyte Count; Leukopenia; Male; Neutropenia; Prospective Studies

2006
Phase I and pharmacokinetic study of pemetrexed administered every 3 weeks to advanced cancer patients with normal and impaired renal function.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Feb-01, Volume: 24, Issue:4

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Drug Administration Schedule; Fatigue; Female; Folic Acid; Glutamates; Guanine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nausea; Neoplasms; Neutropenia; Pemetrexed; Thrombocytopenia; Vitamin B 12

2006
A phase I study of pemetrexed (LY231514) supplemented with folate and vitamin B12 in Japanese patients with solid tumours.
    British journal of cancer, 2006, Sep-18, Volume: 95, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Folic Acid; Glutamates; Guanine; Humans; Infusions, Intravenous; Japan; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Neutropenia; Pemetrexed; Safety; Treatment Outcome; Vitamin B 12

2006
Study of the role of vitamin B12 and folinic acid supplementation in preventing hematologic toxicity of zidovudine.
    European journal of haematology, 1995, Volume: 55, Issue:2

    Topics: Adult; Anemia; Bone Marrow Diseases; CD4 Lymphocyte Count; Female; Folic Acid; Hematologic Diseases; HIV Infections; Humans; Leucovorin; Male; Neutropenia; Prospective Studies; Vitamin B 12; Zidovudine

1995
Phase I study of phosphonacetyl-L-aspartate, 5-fluorouracil, and leucovorin in patients with advanced cancer.
    Cancer chemotherapy and pharmacology, 1995, Volume: 35, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Diarrhea; Digestive System; Drug Synergism; Female; Fluorouracil; Folic Acid; Humans; Leucovorin; Male; Middle Aged; Neoplasms; Neutropenia; Phosphonoacetic Acid; Proportional Hazards Models; Pyrimidines; Remission Induction; Risk Factors; Thymidylate Synthase

1995
A phase I and pharmacokinetic study of 1843U89, a noncompetitive inhibitor of thymidylate synthase, in patients with advanced solid malignancies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exanthema; Female; Folic Acid; Humans; Indoles; Infusions, Intravenous; Isoindoles; Male; Middle Aged; Mouth Mucosa; Neoplasms; Neutropenia; Quinazolines; Stomatitis; Thymidylate Synthase

2001

Other Studies

14 other study(ies) available for folic acid and Neutropenia

ArticleYear
[Safety of pemetrexed according to the duration of vitamin B12 and folic acid supplementation prior to the first dose of pemetrexed].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Diarrhea; Dietary Supplements; Drug Combinations; Exanthema; Female; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Pemetrexed; Retrospective Studies; Vitamin B 12

2015
Factors Associated with Myelosuppression Related to Low-Dose Methotrexate Therapy for Inflammatory Rheumatic Diseases.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Female; Folic Acid; Hematologic Diseases; Humans; Hypoalbuminemia; Male; Methotrexate; Middle Aged; Neutropenia; Pancytopenia; Retrospective Studies; Rheumatic Diseases; Risk Factors; Serum Albumin

2016
Population pharmacokinetic/pharmacodynamic analyses of pemetrexed and neutropenia: effect of vitamin supplementation and differences between Japanese and Western patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jan-01, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Asian People; Dietary Supplements; Female; Folic Acid; Glutamates; Guanine; Humans; Male; Middle Aged; Neutropenia; Pemetrexed; Time Factors; Vitamin B 12; White People

2009
Major and prolonged response to pemetrexed in two cases of lung adenocarcinoma with bronchioloalveolar carcinoma features.
    Lung cancer (Amsterdam, Netherlands), 2009, Volume: 65, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Aged; Antimetabolites, Antineoplastic; Bone Neoplasms; Cough; Disease Progression; Dyspnea; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Neoplasm Staging; Neutropenia; Pemetrexed; Remission Induction; Renal Insufficiency; Smoking; Tomography, X-Ray Computed; Vitamin B 12

2009
Pemetrexed for previously treated patients with non-small cell lung cancer and differences in efficacy according to thymidylate synthase expression.
    Chemotherapy, 2012, Volume: 58, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Folic Acid; Glutamates; Guanine; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nausea; Neutropenia; Pemetrexed; Salvage Therapy; Thrombocytopenia; Thymidylate Synthase; Treatment Outcome

2012
[Effect of vitamin B6 (pyridoxine) and folic acid in benzene neutropenia].
    Schweizerische medizinische Wochenschrift, 1951, Dec-15, Volume: 81, Issue:50

    Topics: Agranulocytosis; Benzene; Folic Acid; Humans; Neutropenia; Pyridoxine; Vitamin B 6

1951
High serum folate values in lambs experimentally infected with Anaplasma phagocytophilum.
    Acta veterinaria Scandinavica, 2003, Volume: 44, Issue:3-4

    Topics: Anaplasma phagocytophilum; Animals; Ehrlichiosis; Folic Acid; Neutropenia; Sheep

2003
Effect of vitamin B12, folate, and dietary supplements on breast carcinoma chemotherapy--induced mucositis and neutropenia.
    Cancer, 2004, Sep-01, Volume: 101, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Dietary Supplements; Female; Folic Acid; Humans; Leukocyte Count; Middle Aged; Mucous Membrane; Neutropenia; Neutrophils; Surveys and Questionnaires; Vitamin B 12

2004
[Nosology and treatment of certain neutropenic conditions].
    Prensa medica argentina, 1950, Apr-14, Volume: 37, Issue:15

    Topics: Agranulocytosis; Folic Acid; Humans; Neutropenia

1950
A semimechanistic-physiologic population pharmacokinetic/pharmacodynamic model for neutropenia following pemetrexed therapy.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:4

    Topics: Adult; Aged; Algorithms; Analysis of Variance; Antimetabolites, Antineoplastic; Area Under Curve; Avitaminosis; Blood Cell Count; Body Surface Area; Clinical Trials, Phase II as Topic; Data Interpretation, Statistical; Female; Folic Acid; Glutamates; Guanine; Humans; Infusions, Intravenous; Leukocyte Count; Male; Middle Aged; Models, Statistical; Neutropenia; Neutrophils; Pemetrexed; Population; Vitamin B 12; Vitamin B 6; Vitamins

2006
Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole).
    Acta paediatrica Scandinavica, 1984, Volume: 73, Issue:6

    Topics: Agranulocytosis; Amoxicillin; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Eosinophilia; Female; Folic Acid; Humans; Infant; Male; Neutropenia; Otitis Media; Risk; Sulfamethoxazole; Time Factors; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1984
Hematologic values and plasma and tissue folate concentrations in dogs given phenytoin on a long-term basis.
    American journal of veterinary research, 1990, Volume: 51, Issue:11

    Topics: Animals; Blood Cell Count; Dog Diseases; Dogs; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Neutropenia; Phenytoin; Radioimmunoassay; Thrombocytopenia; Time Factors

1990
Lithium for zidovudine-induced neutropenia in AIDS.
    JAMA, 1989, Aug-11, Volume: 262, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Agranulocytosis; Folic Acid; Humans; Lithium; Neutropenia; Vitamin B 12; Zidovudine

1989
The effect of folate supplements on 6-mercaptopurine remission maintenance therapy in childhood leukaemia.
    British journal of cancer, 1986, Volume: 53, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Female; Folic Acid; Humans; Leukemia, Lymphoid; Leukocyte Count; Male; Mercaptopurine; Neutropenia; Neutrophils; Thioguanine

1986