folic acid has been researched along with Hyperhomocysteinemia in 1140 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 61 (5.35) | 18.2507 |
| 2000's | 686 (60.18) | 29.6817 |
| 2010's | 296 (25.96) | 24.3611 |
| 2020's | 97 (8.51) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, M; Fu, C; Li, X; Shi, Y; Wang, Y; Xue, H; Yan, Q; Zhu, D | 1 |
| Aiello, V; Angelini, A; Capelli, I; Cappuccilli, ML; Cianciolo, G; Croci Chiocchini, AL; Iacovella, F; Magnoni, G; Mancini, R; Napoletano, A; Troiano, A | 1 |
| Faliva, MA; Fossari, F; Naso, M; Nichetti, M; Perna, S; Peroni, G; Rondanelli, M; Tartara, A; Vecchio, V | 1 |
| Astrup, H; Bjørke-Monsen, AL; Eklund, EA; Hager, HB; Lindberg, M; Ljungblad, UW; Mørkrid, L; Paulsen, H; Pettersen, RD; Rootwelt, T; Tangeraas, T | 1 |
| Chen, X; Huang, X; Jie, D; Shao, W; Wang, G; Wang, X; Zhang, B; Zhang, W; Zheng, C | 1 |
| Dobrowolska, A; Krela-Kaźmierczak, I; Ratajczak, AE; Rychter, AM; Szymczak-Tomczak, A; Zawada, A | 1 |
| Arceni, BS; Barbosa, DS; de Lima Pedrão, JV; Delfino, VDA; Matsumoto, AK; Michelin, AP; Moreira, EG; Porto, GM; Semeão, LO; Sepúlveda-Loyola, W | 1 |
| Brown, CJ; Elias, MF | 1 |
| Chen, X; Huang, X; Wang, X; Zhang, W; Zheng, C | 1 |
| He, H; Hou, A; Luo, M; Ran, S; Song, D; Tang, J; Tang, Y; Wang, H; Wang, T; Yan, X; Yang, R; Yu, B; Zhang, S | 1 |
| Ho, B | 1 |
| Cao, C; Chen, H; Chen, X; Dou, Y; Huang, G; Huang, X; Jiang, Y; Li, M; Ma, X; Sheng, W; Wang, D; Wang, Y; Yan, W; Zhang, Y | 1 |
| Wang, AY; Wu, HHL | 1 |
| Gil, APR; Katsa, ME | 1 |
| Bajic, Z; Djuric, DM; Matavulj, A; Ponorac, N; Skrbic, R; Sobot, T; Stojiljkovic, MP | 1 |
| Ahmed, Z; Andrews, SC; Iqbal, K; Khan, MS; Qadir, SA; Saeedullah, A; Shahzad, B; Shahzad, M | 1 |
| Bala, R; Budhwar, S; Prakash, N; Sachan, S; Verma, R | 1 |
| Abdul Ghani, SAB; Arul, K; Bee, GGB; Cheah, CC; Chow, PKH; Cook, SA; Lim, TR; Pei, HJ; Sandireddy, R; Shekeran, SG; Singh, BK; Singh, MK; Sinha, RA; Suzuki, A; Tikno, K; Tripathi, M; Wang, J; Widjaja, A; Wong, KA; Xiao, RP; Yen, PM; Zhang, X; Zhou, J | 1 |
| Chung, BY; Chung, EH; Eun, YS; Heo, NH; Kim, HO; Kim, JE; Kim, JY; Lee, SH; Lee, SY; Park, CW; Park, YL; Shin, MJ; Yang, NG | 1 |
| Cohen, E; Goldberg, E; Goldberg, I; Krause, I; Lerman, TT; Sochat, T | 1 |
| Balwani, M; Fanelli, MJ; Gouya, L; Longo, N; Petrides, PE; Phillips, J; Plutzky, J; Rhyee, S; Sardh, E; Sweetser, MT; Ventura, P | 1 |
| An, X; Deng, Y; Fan, R; Li, J; Li, Z; Liao, J; Wang, Y; Xia, Y; Yang, X | 1 |
| Burton, GJ; Capatina, N; Yung, HW | 1 |
| Jia, J; Li, T; Quan, M; Song, Y | 1 |
| Guéant, JL; Guéant-Rodriguez, RM; Oussalah, A; Rosenberg, I; Zuily, S | 1 |
| Huang, X; Liu, D; Wu, M | 1 |
| Gambello, MJ; Gonzalez, A; Kožich, V; Li, H; Smith, GH; Sokolová, J | 1 |
| Bao, ZX; Chen, GY; Tang, ZQ | 1 |
| Brisevac, L; Fishchuk, L; Gorovenko, N; Medvedieva, N; Popova, O; Rossokha, Z; Sheyko, L; Stroy, D; Vershyhora, V; Vorobei, L | 1 |
| Abdulhalim, EN; El-Bassyouni, HT; Hamed, K; Hashem, SA; Kamel, SM; Khedr, AA; Youness, ER | 1 |
| Chen, S; Fang, AP; He, TT; Huang, BX; Huang, RZ; Huang, ZH; Li, SY; Liu, XZ; Liu, ZY; Lu, XT; Luo, Y; Maierhaba, W; Mo, QW; Wang, YF; Wang, YN; Yang, MT; Zhang, XG; Zhu, HL | 1 |
| Park, HY; Song, BM; Song, S | 1 |
| Celermajer, DS; Chook, P; Guo, DS; Kwok, CYT; Lin, CQ; Poon, YKP; Woo, KS; Yin, YH | 1 |
| Shi, B; Zhang, M; Zhao, M | 1 |
| Chandratheva, A; Chen, J; Coughlan, CH; Goodison, W; Murphy, E; Rees, A | 1 |
| Huang, W; Wen, C; Xu, R; Yu, X | 1 |
| Chen, GL; Li, L; Liu, H; Lv, L; Ma, Z; Tong, X | 1 |
| Bandopadhayay, S; Dangi, M; Goyal, J; Rana, V; Rao, BV; Sharma, VK; Srikumar, S | 1 |
| Arunachal, G; Bhasin, H; Chandran, M; Danda, S; Garg, D; Korula, S; Malik, P; Oommen, SP; Saini, AG; Sharma, S; Thomas, M; Yoganathan, S | 1 |
| Bao, H; Chen, G; Cheng, X; Cheng, Z; Cui, Y; Ding, C; Hu, L; Huang, X; Huo, Y; Li, P; Qin, X; Sheng, C; Song, D; Tang, G; Wang, J; Wang, X; Wang, Z; Yao, C; Zhang, J | 1 |
| Johnson, S; Piorino, F; Styczynski, MP | 1 |
| Al-Khlaiwi, T; Almushawah, A; Alsomali, A; Habib, SA; Habib, SS | 1 |
| Gu, J; Lei, C; Zhang, M | 1 |
| Chang, JY; Chiang, CP; Sun, A; Wang, YP; Wu, YC; Wu, YH | 9 |
| Chen, J; Chen, Y; Deng, X; Leng, H; Ma, Z; Pan, L; Wu, K; Yin, Y; Zhang, HT | 1 |
| Du, B; Godfrey, O; Huang, X; Li, D; Ren, B; Wang, X; Yue, L; Zhang, C; Zhang, W; Zhao, Q | 1 |
| Abdelmaksoud, A; Ayhan, E; Dönmezdil, S; Jovicevic, TV; Lotti, T; Vestita, M; Vojvodic, A; Vojvodic, P | 1 |
| Abd Al-Badri, HJ; Abdul-Hassan, M | 1 |
| Chang, JY; Kuo, YS; Sun, A; Wang, YP; Wu, YC; Wu, YH | 2 |
| Kumar, S; Singh, NK; Sonkar, SK; Tandon, R | 1 |
| Annunziata, MC; Donnarumma, M; Fabbrocini, G; Marasca, C | 1 |
| Choi, G; Harrison, J; Kwok, T; Lam, L; Lee, J; Lee, R; Lee, V; Mok, V; Wu, Y; Yung, CY | 1 |
| Du, B; Godfrey, O; Huang, X; Li, D; Ren, B; Yang, J; Yue, L; Zhang, C; Zhang, W; Zhao, Q | 1 |
| Du, B; Godfrey, O; Huang, X; Li, D; Ren, B; Yue, L; Zhang, C; Zhang, W; Zhao, Q | 1 |
| Bakardjieva-Mihaylova, V; Dobrovolny, R; Fronkova, E; Jesina, P; Kalina, T; Kanderova, V; Kozich, V; Krijt, J; Mancikova, A; Rackova, M; Skvarova Kramarzova, K; Smisek, P; Sokolova, J; Stary, J; Stiburkova, B; Stuchly, J; Svaton, M; Trka, J; Vodickova, E | 1 |
| Horlenko, FV; Horlenko, OM; Prylypko, LB; Studenyak, VM | 1 |
| Du, B; Huang, X; Li, D; Ren, B; Yue, L; Zhang, C; Zhang, W; Zhao, Q | 1 |
| Bergamini, C; Capelli, I; Cappuccilli, M; Cianciolo, G; Conte, D; Donati, G; Giacomelli, FA; La Manna, G; Natali, T | 1 |
| Chen, X; Huang, X; Li, D; Ren, B; Shi, F; Wang, X; Yue, L; Zhang, C; Zhang, W; Zhao, Q; Zheng, C | 1 |
| Cao, P; Gao, N; Lei, L; Li, L; Lin, L; Xu, R; Zhang, Y; Zhao, X | 1 |
| Chang, G; Heizhati, M; Hong, J; Li, N; Luo, Q; Pan, F; Sun, L; Wang, L; Yue, N; Zhang, D; Zhou, L | 1 |
| De Martinis, M; Fontanella, L; Ginaldi, L; Nocelli, C; Sirufo, MM | 1 |
| Accinni, R; Caimi, TM; Dellanoce, C; Montorsi, M; Mrakic-Sposta, S; Vezzoli, A; Vietti, D | 1 |
| Ali, MM; Bianco, FM; Cristoforo, GP; Frederick, P; Gangemi, A; Haloul, M; Hassan, C; Mahmoud, AM; Masrur, M; Mirza, MI; Naquiallah, D; Phillips, SA; Qureshi, M; Vinjamuri, SJ | 1 |
| George, AK; Homme, RP; Jovanovic, M; Singh, M; Stanisic, D; Tyagi, N; Tyagi, SC | 1 |
| George, AK; Singh, M; Smolenkova, I; Stanisic, D; Tyagi, SC | 1 |
| Cornett, EM; Fuller, MC; Jeha, GM; Kaye, AD; Kevil, CG; Lerner, ZI; Pham, AD; Sibley, GT; Urits, I; Viswanath, O | 1 |
| Chang, JY; Chiang, CP; Sun, A | 1 |
| Maiha, BB; Onyemelukwe, OU | 2 |
| Chang, JY; Chiang, ML; Sun, A; Wang, YP; Wu, YC; Wu, YH | 1 |
| Stabler, SP | 1 |
| Jiang, B; Yao, C; Yao, G; Zheng, N | 1 |
| Fan, W; Feng, Y; Li, A; Liu, X; Pang, J; Tang, L | 1 |
| Dragnić, S; Kraljević, I; Mikhailidis, DP; Muzurović, E; Solak, M | 1 |
| Gabelli, C; Reffo, A | 1 |
| Fishchuk, L; Gorovenko, N; Medvedieva, N; Rossokha, Z; Sheyko, L | 1 |
| Aguilar-González, M; Fernández-Santodomingo, AS; Marín-Payá, E; Rahhal-Ortuño, M; Ramos-González, L; Villena-Alvarado, CK | 1 |
| Bedarf, J; Bidkhori, G; Ehrlich, SD; Hildebrand, F; Le Chatelier, E; Lee, S; Mardinoglu, A; Proctor, G; Rosario, D; Shoaie, S; Uhlen, M; Wüllner, U | 1 |
| Bhattacharyya, A; Kaur, H; Kumar, S; Medhi, B; Prajapat, M; Prakash, A; Sarma, P | 1 |
| Guéant, JL; Jeannesson, E; Levy, J; Oussalah, A; Rodriguez-Guéant, RM; Wahl, D; Ziuly, S | 1 |
| Bjørklund, G; Chirumbolo, S; Dadar, M; Lenchyk, L; Lozynska, I; Lysiuk, R; Peana, M; Severin, B; Upyr, T | 1 |
| MacFarlane, AJ | 1 |
| Aarsand, AK; Aguilera, P; Brunet, M; Deulofeu, R; García-Villoria, J; Gómez-Gómez, À; Pozo, OJ; Sandberg, S; To-Figueras, J; Wijngaard, R | 1 |
| Hwang, MJ; Lee, YP; Lin, CP; Loh, CH | 1 |
| Anusree, VR; Chandran, M; Jaleel, A; Kumar, AA; Lakshmi, S; Pillai, MR; Satheesh, G; Simon, L; Vijayakumar, G | 1 |
| Patel, S; Prajapati, K; Rathod, M; Sailor, V | 1 |
| Anamnart, C; Kitjarak, R | 1 |
| Cao, P; Gao, N; Liu, Z; Wang, G; Xu, R; Zhang, W; Zhao, X | 1 |
| Dai, C; Fei, Y; Li, J; Shi, Y; Yang, X | 1 |
| Agrawal, NR; Bala, R; Rajender, S; Singh, K; Singh, V; Verma, P; Verma, R; Yadav, N | 1 |
| Kalita, J; Misra, UK; Singh, VK | 1 |
| Jin, YT; Lin, PY; Wu, YC; Wu, YH; Yang, JH | 1 |
| Cuoghi, C; Marcacci, M; Pietrangelo, A; Ricci, A; Ventura, P | 1 |
| Li, Z; Ma, X; Xing, C; Xu, R; Zhang, L | 1 |
| Cao, Y; Chai, J; Ji, D; Liu, H; Liu, J; Luo, C; Wang, W; Wu, J; Wu, Y; Xue, K; Yan, W; Zhu, X | 1 |
| Ding, R; Jiang, L; Jiang, Y; Lin, X; Wu, C; Xia, X; Yang, W; Zheng, S | 1 |
| Hiraoka, M; Kagawa, Y | 1 |
| Bandzeviciene, R; Bartkeviciene, D; Bartkeviciute, A; Boreikaite, E; Serapinas, D; Silkunas, M | 1 |
| Dai, XL; Jin, MH; Liu, GC; Mi, NN; Ren, XY; Wang, J; Wang, SQ; Zhang, J | 1 |
| Cappuccilli, M; Cianciolo, G; La Manna, G | 1 |
| Dayer, M; Lathyris, D; Martí-Carvajal, AJ; Solà, I | 1 |
| Adnaoui, M; Ammouri, W; Harmouche, H; Maamar, M; Tazi, ZM | 1 |
| Aguilar-Ros, A; Carson, BP; Díaz-Martínez, ÁE; García-González, Á; Iglesias-Gutiérrez, E; O'Gorman, DJ; Terrados, N; Úbeda, N; Venta, R | 1 |
| Cao, Y; Ding, XM; Hao, XD; Ning, B; Ren, JR; Ren, SH; Wang, S; Wu, J; Zhen, ZG | 1 |
| Kim, J; Kim, JO; Kim, NK; Kim, OJ; Oh, SH; Park, HS; Ryu, CS; Shin, JW | 1 |
| Farina, N; Hart, K; Jernerén, F; Tabet, N; Turner, C | 1 |
| Absalom, AR; de Bock, GH; Gernaat, SAM; Huisman, MG; Izaks, GJ; van der Wal-Huisman, H; van Leeuwen, BL; Weerink, LBM | 1 |
| Di Luigi, L; Romanelli, F; Romano, M; Sansone, A; Sansone, M; Seraceno, S | 1 |
| Jacques, PF; Livingston, K; Rogers, G; Rosenberg, IH; Scott, TM; Selhub, J; Troen, AM; Weiner, DE | 1 |
| Chatterjee, M; Mukhopadhyay, K; Rajamma, U; Ray, A; Saha, T; Sinha, S; Verma, D | 1 |
| Bhide, V; Mahalle, N; Naik, S | 1 |
| Fedorenko, O; Kotova, N; Maichuk, V | 1 |
| Li, J; Wang, C | 1 |
| Bajic, V; Haidara, MA; Isenovic, ER; Jovanovic, M; Obradovic, M; Zaric, BL | 1 |
| Du, B; Ge, M; Hou, Q; Tian, D; Tian, H; Wang, L; Wang, W; Zhang, C; Zhang, W | 1 |
| Kang, SS; Rosenson, RS | 1 |
| Garg, PR; Joshi, S; Saraswathy, KN; Yadav, S | 1 |
| Akrout, R; Ayedi, F; Bahloul, Z; Ben Hamad, M; Chaabane, S; Keskes, L; Maalej, A; Marzouk, S; Messedi, M; Rebai, A; Turki, M | 1 |
| Huang, J; Li, HH; Liang, FL; Mo, JL; Ou, BQ; Peng, Y; Zhou, Z | 1 |
| Chen, M; Gao, X; Li, J | 1 |
| Ozcelik, F; Sertoglu, E | 1 |
| Chrysant, GS; Chrysant, SG | 1 |
| Gaur, R; Kaur, G; Saraswathy, KN; Yadav, S | 1 |
| Shute, C | 1 |
| Benito, PJ; Carru, C; Díaz-Martínez, ÁE; González-Gross, M; González-Lamuño, D; Lopez-Torres, O; Maroto-Sánchez, B; Palacios, G; Valtueña, J; Zinellu, A | 1 |
| Guo, J; Li, Q; Ni, S; Wang, JZ; Yang, Y | 1 |
| Ban, Q; Chen, L; Cui, Y; He, M; Huang, X; Huo, Y; Li, J; Li, Y; Qin, X; Tang, G; Wang, B; Wu, H; Xu, X; Yin, D; Zhang, Y | 1 |
| Jakubowski, H | 1 |
| Chiang, CP; Sun, A; Wang, YP; Wu, YC; Wu, YH; Yu-Fong Chang, J | 3 |
| de Moraes, R; Tibirica, E; Van Bavel, D | 1 |
| Aiello, P; Bello, C; Canali, R; Carminati, D; Comitato, R; Devirgiliis, C; Guantario, B; Meucci, A; Motta, V; Natella, F; Perozzi, G; Roselli, M; Tidona, F; Trevisi, P; Virgili, F; Zinno, P | 1 |
| Capelli, I; Cappuccilli, M; Cianciolo, G; Gasperoni, L; La Manna, G; Tondolo, F; Zappulo, F | 1 |
| Arora, R; Bansal, AK; Bhattacharya, R; Hasan, T; Sharma, GS; Singh, LR | 1 |
| Abe, Y; Ao, M; Inoue, S; Inuiya, N; Kurose, S; Miyawaki, T; Niki, N; Ohta, J; Takaoka, H; Tanaka, K; Tanaka, S | 1 |
| Ansari, SN; Chandel, S; Joshi, PC; Kaur, G; Saraswathy, KN | 1 |
| Alurkar, A; Basavaraj, A; Chandanwale, A; Harale, M; Kadam, DB | 1 |
| Du, B; He, Y; Li, D; Ren, B; Yue, L; Zhang, C; Zhang, W; Zhao, Q | 1 |
| Aroonnual, A; Arthan, D; Chanchai, S; Chantaranipapong, Y; Chupeerach, C; Kaewprasert, S; Nakosiri, W; Nana, A; Paratthakonkun, C; Pooudoung, S; Prangthip, P; Soonthornworasiri, N; Tungtrongchitr, R; Wongsutthilerd, A | 1 |
| Han, H; Ren, B; Tian, D; Tian, H; Wang, L; Wang, W; Yue, L; Zhang, W | 1 |
| Baroni, L; Bazzerla, G; Bertola, C; Bonetto, C; Caberlotto, L; Rizzo, G | 1 |
| Chen, HM; Cheng, SJ; Chu, FY; Sun, A; Wu, YC; Wu, YH | 1 |
| Chellappan, DK; Dahiya, S; Dua, K; Gillhotra, R; Gubbiyappa, SK; Gupta, G; Mishra, A; Samuel, VP; Singh, M; Singh, Y; SreeHarsha, N; Tambuwala, MM | 1 |
| Deng, J; Dong, H; Shen, Y; Xie, Z; Xiong, L; Zhang, P; Zhao, G | 1 |
| Goyal, A; Gupta, JK; Narayan Yadav, H; Qureshi, SS | 1 |
| Buffone, G; de Franciscis, S; De Sarro, G; Gallelli, L; Longo, P; Molinari, V; Serra, R; Stillitano, DM | 1 |
| Garg, MK; Kulkarni, MV; Mahalle, N; Naik, SS | 1 |
| Kim, GH; Kim, SJ; Kim, YM; Lee, BH; Yoo, HW | 1 |
| Ciano, O; Ciati, R; De Natale, C; Luongo, D; Maione, S; Marotta, G; Mazzarella, R; Melegari, C; Minerva, V; Naviglio, D; Patti, L; Riccardi, G; Rivellese, AA; Turco, S | 1 |
| Ghosh, PK; Kaur, L; Mukhopadhhyay, R; Puri, M; Sachdeva, MP; Saraswathy, KN; Trivedi, SS; Walia, GK | 1 |
| Collins, AR; Deary, IJ; Duthie, AC; Duthie, SJ; Lemmon, H; Murray, AD; Staff, RT; Starr, JM; Whalley, LJ | 1 |
| Devlin, AM; Glier, MB; Green, TJ | 1 |
| Andria, G; Carnovale, E; Genovese, O; Giardina, B; Iacoviello, L; Mastroiacovo, P; Minucci, A; Mistura, L; Persichilli, S; Pounis, G; Ricci, R; Ruggeri, S; Scala, I; Turrini, A; Zappacosta, B | 1 |
| Akioka, Y; Chikamoto, H; Hamatani, R; Hattori, M; Otsu, M | 1 |
| Kałużna-Czaplińska, J; Michalska, M; Rynkowski, J; Żurawicz, E | 1 |
| Albright, KA; Neuman, JC; Schalinske, KL | 1 |
| Hoey, L; McNulty, H; Pentieva, K; Strain, J; Ward, M | 1 |
| Dell'edera, D; Domenico, C; Epifania, AA; Francesco, L; Giuseppe, T; Malvasi, A; Marcello, G; Milazzo, GN; Pacella, E; Pierluigi, C; Tinelli, A | 1 |
| Ayedi, F; Bahloul, Z; Chaabouni, Kh; Frigui, M; Jamoussi, K; Lahiyani, A; Messaouad, M; Messedi, M; Neifer, M; Turki, M | 1 |
| Cheng, YY; Hong, Y; Hou, Y; Li, YL; Niu, C; Yu, LX | 1 |
| Cao, L; Huang, X; Lou, X; Mou, N; Tan, H; Wu, W; Zou, Z | 1 |
| Andras, A; Hansrani, M; Stansby, G | 1 |
| Chu, L; Dong, N; Wang, B; Xiao, L | 1 |
| Joseph, J; Loscalzo, J | 1 |
| Brown, K; Givvimani, S; Kalani, A; Kamat, PK; Metreveli, N; Tyagi, N; Tyagi, SC | 1 |
| Chlopocka-Wozniak, M; Dorszewska, J; Permoda-Osip, A; Rybakowski, JK; Skibinska, M | 1 |
| Köz, OG; Kural, G; Oner, V; Türkcü, FM; Yarangümeli, A | 1 |
| Iqbal, MP; Yakub, M | 2 |
| Kundu, S; Metreveli, N; Pushpakumar, SB; Sen, U | 1 |
| Blom, H; Brouwer-Brolsma, EM; de Groot, LC; de Jongh, RT; Dhonukshe-Rutten, RA; Enneman, AW; Feskens, E; Geleijnse, JM; Ham, AH; Lips, P; Mattace-Raso, FU; Smulders, YM; Swart, KM; Uitterlinden, AG; van den Meiracker, AH; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Meurs, J; van Schoor, NM; van Wijngaarden, JP | 1 |
| Belarbi, S; Bendini, M; Chelouti, H; Djerdjouri, B; El Hadi Cherifi, M; Kacimi, G; Khelil, M; Nazef, K; Tazir, M | 1 |
| Cao, H; Hu, H; Hu, X; Li, J; Liu, B; Liu, C; Shao, Y; Wang, J; Xin, S; Zhang, J; Zhang, Q; Zhang, Z | 1 |
| Baszczuk, A; Kopczyński, Z | 1 |
| Dong, N; Tang, X; Xu, B | 1 |
| Cheng, D; Huang, C; Jiang, Y; Kong, H; Lu, H; Pang, W; Yang, H | 1 |
| Ashtiani, MN; Azimi, SZ; Kazemnezhad, E; Khosravi, M; Lebadi, M; Mirzajani, E; Monfared, A | 1 |
| Das, SK; Dhar, P; Hota, KB; Hota, SK; Kumar, A; Mahapatra, BB; Norboo, T; Sharma, VK; Srivastava, RB; Vashishtha, V | 1 |
| Apergis, G; Dimitriadis, G; Fotiou, P; Raptis, A; Theodossiadis, P; Vergados, I | 1 |
| Khanduri, U; Kumar, J; Neogi, SS; Sharma, A; Thomas, M | 1 |
| Baronio, D; Castro, K; Gottfried, C; Klein, Lda S; Perry, IS; Riesgo, R | 1 |
| Arsena, R; Bono, A; Butera, D; Cottone, S; Scazzone, C; Schillaci, R; Tornese, F | 1 |
| Cibor, D; Jurczyszyn, A; Mach, T; Owczarek, D; Sałapa, K | 1 |
| Fang, YL; Guo, JH; Li, CX; Li, Y; Ma, LS; Meng, HX; Min, GW; Niu, XY; Sun, MZ; Wang, TD; Zhang, J; Zhang, W | 1 |
| Aliustaoglu, M; Bilici, A; Ercan, S; Gumus, M; Orcun, A; Seker, M; Sonkaya, A; Ustaalioglu, BB | 1 |
| Cui, W; Liu, J; Sun, X; Xie, X; Zhang, D; Zhu, Y | 1 |
| Cediel, R; Garrido, F; Martínez-Álvarez, C; Martínez-Vega, R; Pajares, MA; Partearroyo, T; Varela-Moreiras, G; Varela-Nieto, I; Zeisel, SH | 1 |
| Chomtho, S; Iamopas, O; Ratanachu-ek, S | 1 |
| Brouwer-Brolsma, EM; Brug, J; de Groot, LC; Dhonukshe-Rutten, RA; Enneman, AW; Ham, AC; Lips, P; Sohl, E; Swart, KM; Uitterlinden, AG; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Meurs, JB; van Schoor, NM; van Wijngaarden, JP; Zillikens, MC | 1 |
| Heil, SG; Mandaviya, PR; Stolk, L | 1 |
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| Eberli, FR; Flammer, Y; Hess, OM; Lange, H; Meier, B; Pin, R; Roffi, M; Schnyder, G; Turi, ZG | 1 |
| Kurabayashi, M; Morita, H; Nagai, R; Saito, Y | 1 |
| Berthold, HK; Bohlmann, AM; Brönstrup, A; Fohr, IP; Nau, H; Pietrzik, K; Prinz-Langenohl, R | 1 |
| Chang, SJ; Chou, HF; Huang, HB; Huang, PC; Hung, CJ; Li, YH; Lin, BF; Lu, SC | 1 |
| Barrera, G; Bunout, D; de la Maza, P; Gattás, V; Hirsch, S; Petermann, M | 1 |
| Buysschaert, M; Dramais, AS; Hermans, MP; Jamart, J; Wallemacq, P | 1 |
| Dupuis, E; Michel, C; Mignon, F; Philit, JB; Queffeulou, G; Vrtovsnik, F | 1 |
| Bataille, P; Billion, S; Cadet, E; Queinnec, C; Rochette, J; Tribout, B; Wheatley, P | 1 |
| Warren, CJ | 1 |
| Abdelfatah, A; Alber, D; Chalopin, JM; Ducloux, D; Motte, G; Toubin, G | 1 |
| Hasty, R; Smolar, EN | 1 |
| Ali, SI; Asker, ME; el-Swefy, SE; Mohamed, HE | 1 |
| Brocheriou, I; Cacoub, P; Cohen, G; Kaloustian, E; Kieffer, E; Piette, JC; Sbai, A | 1 |
| Friedland, RP; Jacobsen, DW; Mizrahi, EH | 1 |
| Sela, BA | 1 |
| Ben-Valid, E; Doncheva, M; el Wahab-Daraushe, A; Gefel, D; Lugassy, G; Sela, BA | 1 |
| Corrocher, R; Faccini, G; Friso, S; Girelli, D; Olivieri, O; Pignatti, PF; Pizzolo, F; Stranieri, C; Trabetti, E | 1 |
| Cheng, WC; Hung, MH; Lin, BB; Lin, JS; Shen, MC; Tsay, W; Wang, YC | 1 |
| Bostom, AG; Sharaf, B | 1 |
| Aukrust, P; Holm, T; Holven, KB; Nenseter, MS; Ose, L | 1 |
| Archetti, S; Assanelli, D; Boldini, A; Bonanome, A; Bonetti, P; Grassi, M; Pagnan, A; Pezzini, A; Ruggeri, G; Salvadori, G | 1 |
| Funamizu, M; Hata, A; Hayashi, K; Hiejima, Y; Hirayama, H; Kawabata, M; Makita, Y; Nakamura, T; Saionji, K; Tago, K; Tajiri, M; Takano, H | 1 |
| Aboubakr, A; Chalopin, JM; Drüeke, T; Ducloux, D; Fournier, V; Massy, ZA; Motte, G; Toubin, G | 1 |
| Deutschmann, H; Haas, A; Renner, W; Schmut, O; Semmelrock, J; Stanger, O; Temmel, W; Weger, M | 1 |
| Snavely, J | 1 |
| Ensunsa, JL; Ma, AA; Mullick, AE; Rutledge, JC; Symons, JD | 1 |
| Ballarin, A; Bissoli, L; Bosello, O; Brocco, G; Caruso, B; Di Francesco, V; Mandragona, R; Trespidi, R; Zamboni, M | 1 |
| Hamulyák, K; Kolbach, DN; Neumann, HA; Spaapen, LJ; Veraart, JC | 1 |
| Mizoguchi, N; Ono, H; Sakamoto, A; Sakura, N | 1 |
| Celermajer, DS; Chan, LL; Cheung, AS; Chook, P; Fung, WH; Lolin, YI; Metreweli, C; Qiao, Mu; Sanderson, JE; Thomas, GN; Woo, KS | 1 |
| Bale, A; Balling, R; Christensen, B; Colmenares, C; Ernest, S; Gilfix, BM; Hosack, A; Mamer, OA; McGrath, J; Nadeau, JH; Rodier, M; Rosenblatt, DS; Sankoff, D | 1 |
| Filipovský, J; Hromádka, M; Mayer, O; Racek, J; Stehlík, P; Svobodová, V; Trefil, L; Zárybnická, M | 1 |
| Camera, L; Camera, MI; Galarza, CR; Janson, JJ; Kordich, L; Mayorga, LM; Morales, M; Murúa, A; Przygoda, PA; Quintana, I; Waisman, G | 1 |
| Ducloux, D; Massy, ZA; Motte, G | 1 |
| Castañon, M; Diaz, ML; Freixas, E; Genoud, V; Kordich, L; Martino, D; Pereyra, H; Schiel, A; Schropp, J; Trimarchi, H | 1 |
| Janssens, Y; van Wersch, JW; Zandvoort, JA | 1 |
| Deutschmann, H; Haas, A; Quehenberger, F; Renner, W; Schmut, O; Semmelrock, J; Stanger, O; Temmel, W; Weger, M | 1 |
| Barron, M; Furie, KL; Kelly, PJ | 1 |
| Malinow, MR; Toole, JF | 1 |
| Ahmad, FU; Devi, JR; Dwivedi, M; Guleria, R; Jain, K; Khanna, N; Luthra, K; Misra, A; Pandey, RM; Sharma, R; Vikram, NK | 1 |
| Costimba, I; Delaportas, N; Georgalidis, C; Kaliolia, I; Karaliotas, G; Katsarou, A; Klonou, E; Koulouridis, E; Krokida, A; Lachanas, A; Panagiotaki, E; Tzilianos, M | 1 |
196 review(s) available for folic acid and Hyperhomocysteinemia
| Article | Year |
|---|---|
The link between homocysteine, folic acid and vitamin B12 in chronic kidney disease.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Dialysis; Vitamin B 12 | 2021 |
Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
Topics: Aged; Bone Density; Dietary Supplements; Eating; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex | 2022 |
Does Folic Acid Protect Patients with Inflammatory Bowel Disease from Complications?
Topics: Anemia; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Gastrointestinal Microbiome; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B 6 | 2021 |
Vitamin B-related Gene Polymorphisms and Cardiovascular Disease.
Topics: Aminohydrolases; Cardiovascular Diseases; Folic Acid; Formate-Tetrahydrofolate Ligase; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Multienzyme Complexes; Neoplasm Proteins; Polymorphism, Genetic; Receptors, Cell Surface; Vitamin B 12; Vitamin B Complex | 2022 |
Homocysteine, Vitamins B6 and Folic Acid in Experimental Models of Myocardial Infarction and Heart Failure-How Strong Is That Link?
Topics: Animals; Folic Acid; Gasotransmitters; Heart Failure; Homocysteine; Hyperhomocysteinemia; Inflammation; Models, Theoretical; Myocardial Infarction; Vitamin B 6; Vitamins | 2022 |
Hyperhomocysteinemia in Cardiovascular Diseases: Revisiting Observational Studies and Clinical Trials.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2023 |
Homocysteine as a predictor and prognostic marker of atherosclerotic cardiovascular disease: a systematic review and meta-analysis.
Topics: Aged; Atherosclerosis; Cardiovascular Diseases; Carotid Intima-Media Thickness; Child; Endothelial Cells; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prognosis; Risk Factors; Vitamin B 12 | 2023 |
Folate and retinal vascular diseases.
Topics: Diabetic Retinopathy; Endothelial Cells; Folic Acid; Glucose; Homocysteine; Humans; Hyperhomocysteinemia; Methionine | 2023 |
Homocysteine, vitamin B12, and folate levels in patients with multiple sclerosis in Chinese population: A case-control study and meta-analysis.
Topics: Adult; Case-Control Studies; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multiple Sclerosis; Vitamin B 12 | 2019 |
Depression, isotretinoin, and folic acid: A practical review.
Topics: Acne Vulgaris; Brain-Derived Neurotrophic Factor; Depression; Fatty Acids; Folic Acid; Humans; Hyperhomocysteinemia; Isotretinoin | 2019 |
Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery.
Topics: Betaine; Cardiovascular Diseases; Choline; Dietary Supplements; DNA Methylation; Eating; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methionine; Nutritional Physiological Phenomena; Renal Insufficiency, Chronic; Uremia; Vitamin B 12; Vitamin B 6 | 2020 |
Gut microbiota and the periodontal disease: role of hyperhomocysteinemia.
Topics: Dysbiosis; Folic Acid; Gastrointestinal Microbiome; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Periodontitis; Probiotics | 2021 |
Folic Acid Supplementation in Patients with Elevated Homocysteine Levels.
Topics: Animals; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2020 |
Alterations in Sulfur Amino Acids as Biomarkers of Disease.
Topics: Alcoholism; Amino Acids, Sulfur; Anemia, Megaloblastic; Biomarkers; Cardiovascular Diseases; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Liver Diseases; Nutritional Status; Obesity; S-Adenosylhomocysteine; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Homocysteine and diabetes: Role in macrovascular and microvascular complications.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Diabetic Nephropathies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2021 |
The role of B vitamins in stroke prevention.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B 12; Vitamin B Complex | 2022 |
A Novel Review of Homocysteine and Pregnancy Complications.
Topics: Abortion, Habitual; Aging; Birth Weight; Diabetes, Gestational; Dietary Supplements; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2021 |
Hyperhomocysteinemia and low vitamin B12 are associated with the risk of early pregnancy loss: A clinical study and meta-analyses.
Topics: Abortion, Spontaneous; Adult; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Nutritional Physiological Phenomena; Meta-Analysis as Topic; Nutritional Status; Odds Ratio; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2021 |
Genetic polymorphisms and folate status.
Topics: Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Gene Expression; Genotype; Humans; Hyperhomocysteinemia; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12 | 2017 |
Homocysteine-lowering interventions for preventing cardiovascular events.
Topics: Angina Pectoris; Cardiovascular Diseases; Cause of Death; Folic Acid; Humans; Hyperhomocysteinemia; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2017 |
Homocysteine and Hyperhomocysteinaemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Avitaminosis; Cystathionine beta-Synthase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B 6 | 2019 |
Analytic Approaches for the Treatment of Hyperhomocysteinemia and Its Impact on Vascular Disease.
Topics: Animals; Betaine; Biomarkers; Cardiovascular Diseases; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Phenotype; Risk Factors; Tetrahydrofolates; Treatment Outcome | 2018 |
The current status of homocysteine as a risk factor for cardiovascular disease: a mini review.
Topics: Atherosclerosis; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex | 2018 |
Homocysteine Modification in Protein Structure/Function and Human Disease.
Topics: Animals; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2019 |
Recurrent aphthous stomatitis - Etiology, serum autoantibodies, anemia, hematinic deficiencies, and management.
Topics: Anemia; Autoantibodies; Erythrocyte Indices; Folic Acid; Hematinics; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Parietal Cells, Gastric; Recurrence; Stomatitis, Aphthous; Vitamin B 12 | 2019 |
Folic Acid and Vitamin B12 Administration in CKD, Why Not?
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Risk Factors; Vitamin B 12 | 2019 |
Disturbed homocysteine metabolism is associated with cancer.
Topics: Alleles; Animals; Cystathionine beta-Synthase; Disease Susceptibility; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Metabolic Networks and Pathways; Neoplasms; Polymorphism, Genetic; Risk Factors; Sulfur; Thromboembolism | 2019 |
Atrophic glossitis: Etiology, serum autoantibodies, anemia, hematinic deficiencies, hyperhomocysteinemia, and management.
Topics: Anemia; Atrophy; Autoantibodies; Erythrocyte Indices; Folic Acid; Folic Acid Deficiency; Glossitis; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Parietal Cells, Gastric; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Combinational effect of angiotensin receptor blocker and folic acid therapy on uric acid and creatinine level in hyperhomocysteinemia-associated hypertension.
Topics: Angiotensin Receptor Antagonists; Creatinine; Folic Acid; Humans; Hyperhomocysteinemia; Hypertension; Observational Studies as Topic; Uric Acid | 2019 |
Methyl nutrients, DNA methylation, and cardiovascular disease.
Topics: Amino Acids; Atherosclerosis; Cardiovascular Diseases; Cysteine; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; Lipid Metabolism; Methionine; Nutritional Status; Risk Factors; S-Adenosylmethionine; Vitamin B Complex | 2014 |
A focus on homocysteine in autism.
Topics: Animals; Autistic Disorder; Avitaminosis; Body Fluids; Cystathionine beta-Synthase; Diet; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B 6 | 2013 |
Homocysteine lowering interventions for peripheral arterial disease and bypass grafts.
Topics: Arteriosclerosis; Disease Progression; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Peripheral Vascular Diseases; Randomized Controlled Trials as Topic; Tetrahydrofolates; Vascular Grafting; Vitamin B Complex | 2013 |
Methoxistasis: integrating the roles of homocysteine and folic acid in cardiovascular pathobiology.
Topics: Cardiovascular Diseases; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Methylation; Oxidation-Reduction; Randomized Controlled Trials as Topic; Vitamin B Complex; Vitamin B Deficiency; Vitamins | 2013 |
[Hyperhomocysteinemia in patients with cardiovascular disease].
Topics: Cardiovascular Diseases; Causality; Comorbidity; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Myocardial Infarction; Risk Factors; Vitamin B 12 | 2014 |
Folic acid and autism: What do we know?
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Autism Spectrum Disorder; Child; Child Nutritional Physiological Phenomena; Diet; Dietary Supplements; Evidence-Based Medicine; Female; Fetal Development; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Reproducibility of Results; Risk Factors | 2016 |
Homocysteine and DNA methylation: a review of animal and human literature.
Topics: Animals; Case-Control Studies; Diet; Dietary Supplements; DNA Methylation; Female; Folic Acid; Gene Knockout Techniques; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Models, Animal; Vitamin B Complex; Vitamin B Deficiency | 2014 |
Characterization and review of MTHFD1 deficiency: four new patients, cellular delineation and response to folic and folinic acid treatment.
Topics: Anemia, Megaloblastic; Cells, Cultured; Fatal Outcome; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Leucovorin; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Severe Combined Immunodeficiency; Young Adult | 2015 |
Homocysteine, iron and cardiovascular disease: a hypothesis.
Topics: Biomarkers; Cardiovascular Diseases; Cystathionine; Dietary Supplements; Folic Acid; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Lipoproteins, LDL; Methionine; Risk Factors; S-Adenosylhomocysteine; Vitamin B Complex | 2015 |
One carbon metabolism and bone homeostasis and remodeling: A review of experimental research and population studies.
Topics: Animals; Bone and Bones; Bone Remodeling; Carbon; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Osteoblasts; Osteoclasts; Vitamin B 12; Vitamin B Deficiency | 2016 |
Interventions for lowering plasma homocysteine levels in dialysis patients.
Topics: Aged; Cardiovascular Diseases; Cause of Death; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Renal Dialysis; Stroke; Venous Thrombosis; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2016 |
Homocysteine, B Vitamins, and Cognitive Impairment.
Topics: Aging; Animals; Biomarkers; Cerebrovascular Circulation; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nootropic Agents; Nutritional Status; Practice Guidelines as Topic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials.
Topics: Aged; Cardiovascular Diseases; Coronary Disease; Dietary Supplements; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Stroke | 2016 |
Determinants of hyperhomocysteinemia in healthy and hypertensive subjects: A population-based study and systematic review.
Topics: Blood Pressure; Body Mass Index; China; Creatinine; Diet, Healthy; Dietary Supplements; Exercise; Female; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Life Style; Male; Risk Factors; Triglycerides; Uric Acid; Vegetables; Vitamin B Complex | 2017 |
Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy.
Topics: Animals; DNA Methylation; Epigenesis, Genetic; Folic Acid; Histones; Homocysteine; Humans; Hyperhomocysteinemia; Metformin; Muscle, Skeletal; Muscular Diseases; Oxidative Stress; RNA Interference; Thiazolidinediones; Vitamin B 12; Vitamin B 6 | 2017 |
Public health significance of elevated homocysteine.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neural Tube Defects; Pregnancy; Public Health; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
The worldwide challenge of the dementias: a role for B vitamins and homocysteine?
Topics: Aged; Aged, 80 and over; Aging; Dementia; Environment; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B Complex | 2008 |
The many faces of geriatric depression.
Topics: Aged; Brain; Depressive Disorder, Major; Early Diagnosis; Folic Acid; Geriatric Psychiatry; Humans; Hyperhomocysteinemia; Pain; Prevalence; Primary Health Care; Risk Factors; Suicide; Vitamin B 12 Deficiency | 2008 |
Epigenetics in hyperhomocysteinemic states. A special focus on uremia.
Topics: Atherosclerosis; Clinical Trials as Topic; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans; Hyperhomocysteinemia; S-Adenosylhomocysteine; Uremia | 2009 |
[Present role of homocysteine in clinical medicine].
Topics: Adolescent; Adult; Cardiovascular Diseases; Child; Child, Preschool; Ectopia Lentis; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Life Style; Male; Middle Aged; Myopia; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2009 |
Homocysteine and peripheral arterial disease: systematic review and meta-analysis.
Topics: Aged; Aged, 80 and over; Biomarkers; Dietary Supplements; Evidence-Based Medicine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Peripheral Vascular Diseases; Treatment Outcome; Up-Regulation | 2009 |
Investigation of inter-individual variability of the one-carbon folate pathway: a bioinformatic and genetic review.
Topics: Animals; Computational Biology; Databases, Genetic; Epigenesis, Genetic; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetics, Population; Humans; Hyperhomocysteinemia; Metabolomics; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Transgenic; Models, Animal; Pharmacogenetics; Phenotype; Polymorphism, Single Nucleotide | 2009 |
[Hyperhomocysteinemia and cardiometabolic risk].
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Deficiency; Vitamins | 2009 |
[Genetic conditioned changes in activity of 5,10-methylenetetrahydrofolate reductase (MTHFR) and recurrent miscarriages].
Topics: Abortion, Habitual; Female; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Frequency; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Polymorphism, Genetic; Pregnancy; Risk Factors; Tetrahydrofolates | 2009 |
Genetics of homocysteine metabolism and associated disorders.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Dehydrogenase (NAD+); Severity of Illness Index; Vitamin B 12; Vitamin B 6 | 2010 |
[Disturbances of homocysteine metabolism as a risk factor of cardiovascular diseases development: effect on prognosis and possibilities of correction with drugs].
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Prognosis; Risk Factors; Russia; Vitamin B Complex | 2010 |
Hyperhomocysteinemia and cardiovascular risk: effect of vitamin supplementation in risk reduction.
Topics: Animals; Cardiovascular Diseases; Folic Acid; Humans; Hyperhomocysteinemia; Risk Factors; Risk Reduction Behavior; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2010 |
The homocysteine controversy.
Topics: Animals; Dissent and Disputes; Epidemiologic Research Design; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mendelian Randomization Analysis; Models, Biological; Severity of Illness Index; Vitamin B Complex | 2011 |
Teratogenicity and underlying mechanisms of homocysteine in animal models: a review.
Topics: Abnormalities, Drug-Induced; Animals; Chickens; Congenital Abnormalities; Embryonic Development; Female; Fetal Development; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Neural Crest; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Rats; Teratogens | 2010 |
[Effects of folic acid supplementation on pregnancy outcomes: a review of randomized clinical trials].
Topics: Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Infant, Newborn; Neural Tube Defects; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Premature Birth; Randomized Controlled Trials as Topic; Research Design; Vitamin B Complex | 2010 |
The homocysteine hypothesis: still relevant to the prevention and treatment of cardiovascular disease?
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Primary Prevention; Vitamin B 6; Vitamin B Complex | 2010 |
Meta-analysis: hyperhomocysteinaemia in inflammatory bowel diseases.
Topics: Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Genetic; Risk Factors; Thromboembolism | 2011 |
Enzymatic and non-enzymatic antioxidative effects of folic acid and its reduced derivates.
Topics: Animals; Antioxidants; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress | 2012 |
Hyperhomocysteinemia in chronic renal failure: alternative therapeutic strategies.
Topics: Acetylcysteine; Cardiovascular Diseases; Drug Resistance; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Dialysis; Risk Factors | 2012 |
[Research advances in the treatment of hyperhomocysteinemia].
Topics: Animals; Betaine; Folic Acid; Genetic Therapy; Humans; Hyperhomocysteinemia; Taurine | 2011 |
Homocysteine-lowering therapy does not lead to reduction in cardiovascular outcomes in chronic kidney disease patients: a meta-analysis of randomised, controlled trials.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Randomized Controlled Trials as Topic | 2012 |
Perinatal folate supply: relevance in health outcome parameters.
Topics: Adult; Anemia, Megaloblastic; Animals; Child; Congenital Abnormalities; European Union; Female; Fetal Development; Folic Acid; Folic Acid Deficiency; Health Status; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Lactation; Male; Maternal Nutritional Physiological Phenomena; Nutrition Policy; Nutritional Requirements; Pregnancy | 2010 |
[The role of homocysteine and methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase polymorphisms in the development of cardiovascular diseases and hypertension].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cardiovascular Diseases; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide | 2012 |
[Homocysteine, vitamin B-12, folic acid and the cognitive decline in the elderly].
Topics: Aged; Brain; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nutritional Physiological Phenomena; Receptors, N-Methyl-D-Aspartate; Risk Factors; Vitamin B 12 | 2013 |
The effect of folic acid based homocysteine lowering on cardiovascular events in people with kidney disease: systematic review and meta-analysis.
Topics: Aged; Cardiovascular Diseases; Dietary Supplements; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Randomized Controlled Trials as Topic; Risk Factors | 2012 |
The nutritional burden of methylation reactions.
Topics: Animals; Betaine; Cardiovascular Diseases; Choline; Creatine; Diet; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Methionine; Methylation; Nutritional Status; Phosphatidylcholines | 2013 |
Lowering homocysteine levels with folic acid and B-vitamins do not reduce early atherosclerosis, but could interfere with cognitive decline and Alzheimer's disease.
Topics: Alzheimer Disease; Atherosclerosis; Cognition; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2013 |
Homocysteine-lowering therapy with folic acid is effective in cardiovascular disease prevention in patients with kidney disease: a meta-analysis of randomized controlled trials.
Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Diseases; Kidney Failure, Chronic; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Risk; Severity of Illness Index | 2013 |
Elevated homocysteine? Consider testing for folate metabolism gene variants.
Topics: Alleles; Folic Acid; Genetic Testing; Genetic Variation; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide | 2012 |
Treatment of hyperhomocysteinemia and its impact on disease.
Topics: Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Risk Factors | 2002 |
In vivo stable isotope measurements of methyl metabolism: applications in pathophysiology and interventions.
Topics: Deuterium Oxide; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Kidney Failure, Chronic; Methionine; Methylation; Serine; Tomography, Emission-Computed; Tritium | 2002 |
Pharmacotherapy of hyperhomocysteinaemia in patients with thrombophilia.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Pyridoxine; Renal Insufficiency; Thrombophilia; Vitamin B 12; Vitamins | 2002 |
Hyperhomocysteinemia and transplant coronary artery disease.
Topics: Animals; Coronary Disease; Folic Acid; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine | 2002 |
Fenofibrate-induced hyperhomocysteinaemia: clinical implications and management.
Topics: Arteriosclerosis; Fenofibrate; Folic Acid; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Kidney; Vitamin B 12 | 2003 |
The methionine-homocysteine cycle and its effects on cognitive diseases.
Topics: Alzheimer Disease; Cardiovascular Diseases; Cognition Disorders; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Memory Disorders; Methionine; Methionine Adenosyltransferase; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2003 |
Reducing coronary artery disease by decreasing homocysteine levels.
Topics: Coronary Disease; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Nurse's Role; Patient Education as Topic; Primary Prevention; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
[Cellular and molecular mechanism of cardiovascular disease resulting from hyperhomocysteinemia].
Topics: Animals; Arteriosclerosis; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Rats | 2002 |
Homocysteine and atherothrombosis: diagnosis and treatment.
Topics: Arteriosclerosis; Coronary Disease; Endothelium, Vascular; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidative Stress; Polymorphism, Genetic; Thrombosis | 2003 |
[Homocysteine and coronary artery disease].
Topics: Coronary Artery Disease; Dietary Supplements; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2003 |
Organic nitrate tolerance and endothelial dysfunction: role of folate therapy.
Topics: Animals; Antioxidants; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Mice; Models, Biological; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitro Compounds; Nitroglycerin; Oxidative Stress; Rabbits; Tachyphylaxis; Vasodilator Agents | 2003 |
Changes in haemostasis during normal pregnancy: does homocysteine play a role in maintaining homeostasis?
Topics: Female; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Neural Tube Defects; Placenta Diseases; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Thromboembolism | 2003 |
Homocysteine and essential hypertension.
Topics: Antioxidants; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Muscle, Smooth, Vascular; Nitric Oxide; Vitamin B 12 | 2003 |
[Homocysteine as a coronary risk factor].
Topics: Alcoholic Beverages; Arteriosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Disease; Diet; Female; Folic Acid; Glycine max; Homocysteine; Humans; Hyperhomocysteinemia; Male; Platelet Aggregation; Risk Factors; Vitamin B 12; Vitamin B 6 | 2003 |
[Public health control of hyperhomocysteinemia and its consequences].
Topics: Alzheimer Disease; Canada; Cardiovascular Diseases; Flour; Folic Acid; Food, Fortified; Hematinics; Homocysteine; Humans; Hungary; Hyperhomocysteinemia; Neoplasms; Neural Tube Defects; Primary Prevention; Public Health; Randomized Controlled Trials as Topic; United Kingdom; United States; Vitamin B Complex; Vitamin B Deficiency | 2003 |
Update on cobalamin, folate, and homocysteine.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Metabolism, Inborn Errors; Polymorphism, Genetic; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
DACH-LIGA homocystein (german, austrian and swiss homocysteine society): consensus paper on the rational clinical use of homocysteine, folic acid and B-vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations.
Topics: Austria; Cardiovascular Diseases; Female; Folic Acid; Germany; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Switzerland; Thrombosis; Vitamin B 12; Vitamin B 6 | 2003 |
Does homocysteine cause hypertension?
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Metabolic Syndrome; Pyridoxine | 2003 |
Interactions of homocysteine, nitric oxide, folate and radicals in the progressively damaged endothelium.
Topics: Endothelium, Vascular; Folic Acid; Free Radicals; Homocysteine; Humans; Hyperhomocysteinemia; Nitric Oxide; Vascular Diseases | 2003 |
Homocysteine-lowering therapy in renal disease.
Topics: Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Vitamin B 6 | 2003 |
[Folic acid: new indications for an old well-known drug].
Topics: Adult; Female; Folic Acid; Humans; Hyperhomocysteinemia; Pregnancy | 2003 |
Folate, homocysteine, endothelial function and cardiovascular disease.
Topics: Antioxidants; Cardiovascular Diseases; Endothelium, Vascular; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Risk Factors; Vitamin B Complex | 2004 |
Homocysteine and post-angioplasty restenosis.
Topics: Angioplasty, Balloon, Coronary; Coronary Restenosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Postoperative Complications; Risk Factors | 2003 |
[Folic acid deficiency].
Topics: Dementia; Diagnosis, Differential; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Injections, Intramuscular | 2004 |
Preventing restenosis in CAD patients. Folate therapy reduces homocysteine--and risk.
Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Drug Monitoring; Folic Acid; Humans; Hyperhomocysteinemia; Morbidity; Patient Selection; Recurrence; United States | 2004 |
[Homocysteine and neuropsychiatric disorders].
Topics: Alzheimer Disease; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mental Disorders; Parkinson Disease; Risk Factors; Stroke; Vitamin B 12; Vitamin B 6 | 2004 |
[Homocysteine: why is it harmful?].
Topics: Adenosine; Folic Acid; Homocystinuria; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2004 |
Clinical use and rational management of homocysteine, folic acid, and B vitamins in cardiovascular and thrombotic diseases.
Topics: Cardiovascular Diseases; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Patient Care Management; Practice Guidelines as Topic; Thrombosis; Vitamin B Complex | 2004 |
[Folate against hyperhomocysteinemia. A new approach for the prevention and therapy of alcoholism-associated disorders?].
Topics: Alcohol Withdrawal Seizures; Alcohol-Related Disorders; Alcoholism; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Patient Care Management | 2004 |
[Hyperhomocysteinemia: from theory and practice in the treatment of thrombophilias].
Topics: Administration, Oral; Anticoagulants; Blood Coagulation Tests; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Marfan Syndrome; Multicenter Studies as Topic; Mutation; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Risk Factors; Thrombophilia; Time Factors; Venous Thrombosis; Vitamin B 12; Vitamin B 6 | 2004 |
Homocysteine: is it a clinically important cardiovascular risk factor?
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Myocardial Infarction; Reference Values; Risk Factors; Vitamin B Complex | 2004 |
[Role of folates in the nutrition of the elderly].
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cognition Disorders; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Food, Fortified; Health Education; Humans; Hyperhomocysteinemia; Male; Neoplasms; Nutrition Policy; Nutritional Status; Poland; Primary Prevention; Risk Factors | 2004 |
Mapping the theories of preeclampsia: the role of homocysteine.
Topics: Adult; Age Factors; Biomarkers; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Maternal Age; Parity; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Primary Prevention; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Survival Rate; Vitamin B 12 | 2005 |
Methotrexate reduces incidence of vascular diseases in veterans with psoriasis or rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Cohort Studies; Comorbidity; Databases, Factual; Drug Synergism; Drug Therapy, Combination; Female; Florida; Folic Acid; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Incidence; Male; Medical Records Systems, Computerized; Methotrexate; Middle Aged; Psoriasis; Retrospective Studies; Risk; Vascular Diseases; Veterans | 2005 |
Homocysteine and cardiovascular disease: a review of current recommendations for screening and treatment.
Topics: Cardiovascular Diseases; Epidemiologic Studies; Evidence-Based Medicine; Folic Acid; Health Promotion; Health Services Needs and Demand; Humans; Hyperhomocysteinemia; Mass Screening; Nurse Practitioners; Nurse's Role; Nursing Assessment; Practice Guidelines as Topic; Primary Health Care; Primary Prevention; Randomized Controlled Trials as Topic; Risk Factors; United States | 2005 |
[Homocysteine, folic acid, group B vitamins and cardiovascular risk].
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2005 |
Metabolism of homocysteine and its relationship with cardiovascular disease.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 2004 |
Folic acid supplementation to prevent adverse events in individuals with chronic kidney disease and end stage renal disease.
Topics: Cardiovascular Diseases; Chronic Disease; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Diseases; Kidney Failure, Chronic | 2005 |
[Determination and utilisation of the plasmatic concentration of homocysteine in clinical practice].
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2005 |
Health implications of homocysteine and folates: possible preventive measures.
Topics: Aging; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Preventive Medicine; Risk Factors; Sex Characteristics | 2005 |
Alcohol, methylenetetrahydrofolate 677C->T genotype, and low folate intake: concurrent causes for hyperhomocysteinemia.
Topics: Alcoholism; Animals; Coronary Disease; Ethanol; Female; Folic Acid; Folic Acid Deficiency; Genotype; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2) | 2005 |
Homocysteine and endothelial function in human studies.
Topics: Blood Flow Velocity; Endothelium, Vascular; Folic Acid; Hematinics; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Vascular Diseases; Vasodilation | 2005 |
Homocysteine and folic acid: implications for pregnancy.
Topics: Canada; Female; Folic Acid; Food, Fortified; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; International Cooperation; National Health Programs; Neural Tube Defects; Pre-Eclampsia; Pregnancy; United States | 2005 |
Homocysteine and folate metabolism in depression.
Topics: Animals; Depression; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Models, Biological; Neurotransmitter Agents; Vitamin B 12 Deficiency | 2005 |
The central nervous system in animal models of hyperhomocysteinemia.
Topics: Animals; Central Nervous System; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Homocystine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12 | 2005 |
Research goals for folate and related B vitamin in Europe.
Topics: Biological Availability; Folic Acid; Food Technology; Food, Fortified; Humans; Hyperhomocysteinemia; Intestinal Absorption; Neural Tube Defects; Vitamin B 12; Vitamin B Complex | 2006 |
[Homocysteine--risk factor or risk indicator?].
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Child; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Vitamin B Complex | 2005 |
The many facets of hyperhomocysteinemia: studies from the Framingham cohorts.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Dementia; Diet; Female; Folic Acid; Fractures, Bone; Heart Failure; Homocysteine; Humans; Hyperhomocysteinemia; Male; Massachusetts; Middle Aged; Risk Factors; Stroke; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
Vitamins and minerals 4: overview of folate and the B vitamins.
Topics: Alzheimer Disease; Cardiovascular Diseases; Chemoprevention; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neoplasms; Primary Prevention; Risk Factors; Risk Reduction Behavior; Vitamin B 12; Vitamin B 6 | 2006 |
Homocysteine lowering with folic acid and vitamin B supplements: effects on cardiovascular disease in older adults.
Topics: Adult; Aging; Animals; Cardiovascular Diseases; Clinical Trials as Topic; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex; Vitamin B Deficiency | 2006 |
Is plasma homocysteine a modifiable risk factor for stroke?
Topics: Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Stroke; Thrombosis; Vitamins | 2006 |
Significance of hyperhomocysteinemia.
Topics: Age Factors; DNA Methylation; Female; Folic Acid; Heart Failure; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Osteoporosis; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12 | 2006 |
Synergy of genes and nutrients: the case of homocysteine.
Topics: Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Mood Disorders; Neoplasms; Public Health; Selection, Genetic; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
[Homocysteine and diabetic macroangiopathy].
Topics: Arteriosclerosis; Diabetic Angiopathies; Folic Acid; Humans; Hyperhomocysteinemia; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2006 |
Biochemistry of homocysteine in health and diseases.
Topics: Animals; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Chemical; Oxidative Stress; Smoking; Thrombosis; Vitamin B 12; Vitamin B 6 | 2006 |
Hyperhomocysteinemia and cardiovascular risk in postmenopausal women: the role of folate supplementation.
Topics: Cardiovascular Diseases; Dietary Supplements; Endothelium, Vascular; Female; Folic Acid; Humans; Hyperhomocysteinemia; Postmenopause | 2007 |
[Hyperhomocysteinemia in pediatric age and nutritional aspects of folates: an early cardiovascular risk factor].
Topics: Atherosclerosis; Cardiovascular Diseases; Drug Therapy, Combination; Endothelium; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Hyperhomocysteinemia and cobalamin disorders.
Topics: Biological Transport; Folic Acid; Humans; Hyperhomocysteinemia; Intrinsic Factor; Metabolism, Inborn Errors; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Vitamin B 12 Deficiency | 2007 |
[Risk factors for cardiovascular diseases: what is the role for homocysteine?].
Topics: Cardiovascular Diseases; Folic Acid; Follow-Up Studies; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6 | 2007 |
The homocysteine hypothesis of depression.
Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Child; Comorbidity; Depressive Disorder; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mutation; Neurotransmitter Agents; Stroke; Vitamin B 12; Vitamin B 6 | 2007 |
[Nutritional medicine 2007].
Topics: Cardiovascular Diseases; Diet; Evidence-Based Medicine; Fatty Acids, Omega-3; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Practice Guidelines as Topic; Primary Prevention; Risk Assessment; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine lowering and cardiovascular disease risk: lost in translation.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Risk Factors; Survival Rate; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine and cardiovascular disease: a review of the evidence.
Topics: Biomarkers; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Risk Assessment; Risk Factors; Treatment Outcome; Up-Regulation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
[Review of the role of hyperhomocysteinemia and B-vitamin deficiency in neurological and psychiatric disorders--current evidence and preliminary recommendations].
Topics: Aged; Central Nervous System; Child; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mental Disorders; Nervous System Diseases; Parkinson Disease; Risk Factors; Vitamin B 12; Vitamin B Deficiency | 2007 |
Homocysteine and cerebral stroke in developing countries.
Topics: Developing Countries; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Networks and Pathways; Nutritional Status; Stroke; Vitamin B 12 | 2007 |
Homocysteine, folates, and the eye.
Topics: Dietary Supplements; Eye Diseases; Folic Acid; Humans; Hyperhomocysteinemia; Public Health; Retinal Diseases; Vascular Diseases | 2008 |
Hyperhomocysteinemia: clinical and therapeutical involvement in venous thrombosis.
Topics: Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Risk Factors; Venous Thromboembolism; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2007 |
Mecobalamin.
Topics: Aged; Alprostadil; Animals; Cobamides; Coenzymes; Diabetic Neuropathies; Drug Administration Routes; Drug Therapy, Combination; Female; Folic Acid; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Kidney Failure, Chronic; Male; Metformin; Methionine; Methyltransferases; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Renal Dialysis; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2008 |
Should all elderly people receive folate supplements?
Topics: Aged; Aging; Coronary Disease; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Nutritional Requirements; Nutritional Status | 1998 |
Can dietary supplements with folic acid or vitamin B6 reduce cardiovascular risk? Design of clinical trials to test the homocysteine hypothesis of vascular disease.
Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine; Randomized Controlled Trials as Topic; Research Design; Vitamin B 12 | 1998 |
Hyperhomocysteinemia, atherosclerosis and thrombosis.
Topics: Adult; Aged; Animals; Arteriosclerosis; Avitaminosis; Case-Control Studies; Clinical Trials as Topic; Cohort Studies; Cross-Sectional Studies; Cystathionine beta-Synthase; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle, Smooth, Vascular; Oxidoreductases Acting on CH-NH Group Donors; Prevalence; Primates; Prospective Studies; Pyridoxine; Risk Factors; Smoking; Tamoxifen; Thrombophilia; Thrombosis; Vitamin B 12 | 1999 |
[Hyperhomocysteinemia as a risk factor for venous thrombosis].
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Venous Thrombosis; Vitamin B 12 | 1999 |
Homocysteine and the heart.
Topics: Adult; Coronary Disease; Folic Acid; Humans; Hyperhomocysteinemia; Male; Pyridoxine; Risk Factors | 1999 |
[Homocysteinemia and vascular disease--a new risk factor is born].
Topics: Arteriosclerosis; Cardiovascular Diseases; Folic Acid; Humans; Hyperhomocysteinemia; Pyridoxine; Risk Factors; Vitamin B 12 | 1999 |
[Homocysteine and cardiovascular risk].
Topics: Arteriosclerosis; Cardiovascular Diseases; Folic Acid; Homocystinuria; Humans; Hyperhomocysteinemia; Pyridoxine; Risk Factors; Vitamin B 12 | 1999 |
[Hyperhomocysteinemia: a risk factor for arterial and venous thrombosis].
Topics: Arteriosclerosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine; Risk Factors; Thromboembolism; Vitamin B 12 | 1999 |
Homocyst(e)ine, atherosclerosis, and thrombosis.
Topics: Adult; Aged; Arteriosclerosis; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Hyperhomocysteinemia; Male; Middle Aged; Thrombosis | 1999 |
[Hyperhomocysteinemia, a risk factor for atherosclerosis: causes and effects].
Topics: Age Factors; Arterial Occlusive Diseases; Arteriosclerosis; Cerebrovascular Disorders; Coronary Disease; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Metabolism; Lipoproteins; Male; Meta-Analysis as Topic; Methionine; Middle Aged; Peripheral Vascular Diseases; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors | 1999 |
Hyperhomocysteinemia: an additional cardiovascular risk factor.
Topics: Cardiovascular Diseases; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Prognosis; Risk Assessment; Risk Factors | 1999 |
Homocysteine, B vitamins, and coronary artery disease.
Topics: Clinical Trials as Topic; Coronary Artery Disease; Folic Acid; Humans; Hyperhomocysteinemia; Myocardial Infarction; Recurrence; Risk Factors; Vitamin B Deficiency | 2000 |
Hyperhomocysteinemia in organ transplantation.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Organ Transplantation; Polymorphism, Genetic; Pyridoxine; Risk Factors; Vitamin B 12 | 2000 |
Clinical relevance of hyperhomocysteinaemia in atherothrombotic disease.
Topics: Arteriosclerosis; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thrombosis | 2000 |
Homocysteine and ischaemic heart disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Cohort Studies; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Ischemia; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Retrospective Studies | 1999 |
Homocysteine, folate enzymes and neural tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Pregnancy Complications; Vitamin B 12 | 1999 |
Homocysteine and cardiovascular disease: cause or effect?
Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases | 2000 |
The controversy over homocysteine and cardiovascular risk.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Kidney Diseases; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Prospective Studies; Risk Factors; Vitamin B Complex | 2000 |
Preventive health care, 2000 update: screening and management of hyperhomocysteinemia for the prevention of coronary artery disease events. The Canadian Task Force on Preventive Health Care.
Topics: Aged; Arteriosclerosis; Canada; Coronary Disease; Dietary Supplements; Disease Susceptibility; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Methionine; Preventive Medicine; Pyridoxine; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12 | 2000 |
Hyperhomocysteinemia and thrombosis.
Topics: Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Male; Pregnancy; Risk Factors; Thrombosis | 2000 |
Homocysteine--relevant for atherogenesis?
Topics: Arteriosclerosis; Case-Control Studies; Coronary Disease; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Prospective Studies; Pyridoxine; Retrospective Studies; Risk Factors; Vitamin B 12 | 2000 |
Homocysteine and coronary risk.
Topics: Age Factors; Clinical Trials as Topic; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Risk Factors; Sex Factors | 1999 |
Clinical and laboratory features and sequelae of deficiency of folic acid (folate) and vitamin B12 (cobalamin) in pregnancy and gynecology.
Topics: Anemia, Megaloblastic; Anemia, Pernicious; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Neoplasms; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Genetic modulation of homocysteinemia.
Topics: Amino Acid Substitution; Cardiovascular Diseases; Cystathionine beta-Synthase; Cysteine; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methyltransferases; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Sulfur; Tetrahydrofolates | 2000 |
Mild hyperhomocysteinemia is an independent risk factor of arterial vascular disease.
Topics: Arteriosclerosis; Case-Control Studies; Clinical Trials as Topic; Comorbidity; Coronary Disease; Folic Acid; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Hypertension; Meta-Analysis as Topic; Multicenter Studies as Topic; Oxidative Stress; Pyridoxine; Risk Factors; Smoking; Vitamin B 12 | 2000 |
Homocysteine and renal disease.
Topics: Adult; Arteriosclerosis; Cardiovascular Diseases; Case-Control Studies; Child; Endothelium, Vascular; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Life Tables; Male; Methionine; Peritoneal Dialysis; Prospective Studies; Pyridoxine; Renal Dialysis; Survival Analysis; Thrombophilia; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2000 |
Vitamin supplements and cardiovascular risk: review of the randomized trials of homocysteine-lowering vitamin supplements.
Topics: Adult; Aged; Cardiovascular Diseases; Clinical Trials as Topic; Diet; Double-Blind Method; Drug Synergism; Europe; Female; Folic Acid; Forecasting; Genetic Variation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; North America; Prospective Studies; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Treatment Outcome; Vitamin B 12 | 2000 |
Vascular complications of severe hyperhomocysteinemia in patients with homocystinuria due to cystathionine beta-synthase deficiency: effects of homocysteine-lowering therapy.
Topics: Adolescent; Adult; Aged; Australia; Child; Child, Preschool; Cohort Studies; Cystine; Drug Resistance; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Infant; Ireland; Male; Methionine; Middle Aged; Netherlands; Pyridoxine; Risk; Risk Factors; Thrombophilia; Vascular Diseases; Vitamin B 12 | 2000 |
Fortifying food with folic acid.
Topics: Bread; Case-Control Studies; Colonic Neoplasms; Dietary Supplements; Dose-Response Relationship, Drug; Edible Grain; Europe; Flour; Folic Acid; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Incidence; Legislation, Food; Myocardial Ischemia; Neural Tube Defects; Nutritional Requirements; Odds Ratio; Prospective Studies; Stroke; United States | 2000 |
Homocysteine and neurologic disease.
Topics: Brain Diseases; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Pyridoxine; Vascular Diseases; Vitamin B 12 | 2000 |
Therapeutic potential of total homocysteine-lowering drugs on cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Renal Dialysis; Risk Factors; Vitamin B 12 | 2000 |
Folate and homocysteine.
Topics: Blood Vessels; Cardiovascular Diseases; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Polymorphism, Genetic; Risk Factors; Vitamin B Complex | 2000 |
Homocysteine metabolism in renal failure.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases | 2001 |
Homocysteine: a new cardiac risk factor?
Topics: Coronary Artery Disease; Coronary Disease; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Risk Factors | 2001 |
Homocysteine--a novel risk factor for vascular disease.
Topics: Adult; Arteriosclerosis; Child; Child, Preschool; Coronary Disease; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Risk Factors; United Kingdom; Vitamin B 12 | 2001 |
[Homocysteine, endothelial dysfunction and cardiovascular risk: pathomechanisms and therapeutic options].
Topics: Adult; Aged; Cardiovascular Diseases; Clinical Trials as Topic; Drug Therapy, Combination; Endothelium, Vascular; Female; Fibrinolysis; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Time Factors; Vitamin B Complex | 2001 |
[Homocysteine and cardiovascular risk].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Arteriosclerosis; Clinical Trials as Topic; Coronary Artery Disease; Disease Models, Animal; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Vitamin B 12 | 2001 |
Clotting disorders and placental abruption: homocysteine--a new risk factor.
Topics: Abruptio Placentae; Blood Coagulation Disorders; Endothelium, Vascular; Female; Fetal Growth Retardation; Folic Acid; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Pregnancy Complications, Hematologic; Risk Factors | 2001 |
Impaired homocysteine metabolism and atherothrombotic disease.
Topics: Age Factors; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Models, Chemical; Risk Factors; S-Adenosylmethionine; Sex Factors | 2001 |
[From gene to disease; from homocysteine to hyperhomocysteinemia].
Topics: Cystathionine beta-Synthase; Folic Acid; Heterozygote; Homocysteine; Homocystinuria; Homozygote; Humans; Hyperhomocysteinemia; Methionine; Mutation; Risk Factors; Vascular Diseases | 2001 |
[Polymorphism of the methylenetetrahydrofolate reductase gene (MTHFR) and incidence of hyperhomocysteinemia-related diseases].
Topics: Folic Acid; Gene Expression Regulation, Enzymologic; Gene Frequency; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Incidence; Methylenetetrahydrofolate Dehydrogenase (NADP); Mutation; Polymorphism, Genetic; Risk Factors; Spinal Dysraphism | 2001 |
Does lowering plasma homocysteine reduce vascular disease risk?
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pyridoxine; Risk Factors; Vascular Diseases | 2001 |
[Homocysteine--a risk factor for atherosclerosis].
Topics: Antioxidants; Arteriosclerosis; Disease Progression; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Oxidative Stress; Risk Factors; Thrombosis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2001 |
Treatment of hyperhomocysteinemia in end-stage renal disease.
Topics: Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Tetrahydrofolates; Vitamin B 12; Vitamin B 6 | 2001 |
Homocysteine, folate, and cardiovascular disease.
Topics: Antioxidants; Cardiovascular Diseases; Europe; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Primary Prevention; Risk Factors; Vegetables | 2001 |
Hyperhomocysteinaemia in patients with peripheral arterial occlusive disease.
Topics: Arterial Occlusive Diseases; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 6 | 2001 |
Folate, homocysteine, endothelial function and cardiovascular disease. What is the link?
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Endothelium, Vascular; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Nitric Oxide; Oxidoreductases Acting on CH-NH Group Donors; Vitamins | 2001 |
Cardiovascular risk in the Asia-Pacific region from a nutrition and metabolic point of view: vitamin deficiencies.
Topics: Aged; Antioxidants; Asia; Avitaminosis; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pacific Islands; Risk Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Therapy of hyperhomocysteinemia in end-stage renal disease patients.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Replacement Therapy; Vitamin B 12; Vitamin B 6 | 2001 |
Assessment of homocysteine as a cardiovascular risk factor in clinical practice.
Topics: Biomarkers; Blood Chemical Analysis; Cardiovascular Diseases; Clinical Trials as Topic; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Mutation; Risk Factors; Vitamin B 12 | 2001 |
Emergent cardiovascular risk factor: homocysteine.
Topics: Blood Chemical Analysis; Cardiovascular Diseases; Folic Acid; Health Education; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 6 | 2002 |
Homocysteine.
Topics: Arteriosclerosis; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Diseases | 2002 |
Plasma homocysteine: a new risk factor for Alzheimer's disease?
Topics: Alzheimer Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2002 |
Hyperhomocysteinemia in end stage renal disease: is treatment necessary?
Topics: Arteriosclerosis; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic | 2002 |
Hyperhomocyst(e)inemia as a risk factor after renal transplantation.
Topics: Cardiovascular Diseases; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Risk Factors | 2001 |
170 trial(s) available for folic acid and Hyperhomocysteinemia
| Article | Year |
|---|---|
A Randomized Trial of Short-term Treatment with Folic Acid to Reduce the Oxidative Stress of Patients with Chronic Kidney Disease.
Topics: Aged; Antioxidants; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitrosative Stress; Oxidation-Reduction; Oxidative Stress; Renal Insufficiency, Chronic; Treatment Outcome | 2021 |
Effects of individualized administration of folic acid on prothrombotic state and vascular endothelial function with H-type hypertension: A double-blinded, randomized clinical cohort study.
Topics: Amlodipine; Cohort Studies; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Precision Medicine; Vascular Endothelial Growth Factor A | 2022 |
Adolescent Afghan Refugees Display a High Prevalence of Hyperhomocysteinemia and Associated Micronutrients Deficiencies Indicating an Enhanced Risk of Cardiovascular Disease in Later Life.
Topics: Adolescent; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Micronutrients; Prevalence; Refugees; Vitamin B 12 | 2022 |
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial.
Topics: Adolescent; Adult; Aged; Betaine; Dietary Supplements; Double-Blind Method; East Asian People; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 12; Vitamin B Complex; Young Adult | 2023 |
Combined use of amlodipine and folic acid are significantly more efficacious than amlodipine alone in lowering plasma homocysteine and blood pressure among hypertensive patients with hyperhomocysteinemia and intolerance to ACEI: A multicenter, randomized,
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Stroke; Treatment Outcome | 2023 |
A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients.
Topics: Aged; Aged, 80 and over; Cognition; Cognitive Dysfunction; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2020 |
Influence of Dietary Supplementation for Hyperhomocysteinemia Treatments.
Topics: Adult; Aged; Cysteine; Dietary Supplements; Dipeptides; Female; Folic Acid; Glutathione; Humans; Hyperhomocysteinemia; Male; Middle Aged; Proline; Tetrahydrofolates; Treatment Outcome | 2020 |
Effects of vitamin B12, folate, and entacapone on homocysteine levels in levodopa-treated Parkinson's disease patients: A randomized controlled study.
Topics: Aged; Antiparkinson Agents; Catechols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Research Design; Vitamin B 12 | 2021 |
Muscular contraction frequency does not affect plasma homocysteine concentration in response to energy expenditure- and intensity-matched acute exercise in sedentary males.
Topics: Adult; Anthropometry; Cross-Over Studies; Diet; Energy Metabolism; Exercise; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Muscle Contraction; Nutritional Status; Physical Endurance; Sedentary Behavior; Vitamin B 12; Vitamin B 6; Young Adult | 2018 |
B-Vitamin Therapy for Kidney Transplant Recipients Lowers Homocysteine and Improves Selective Cognitive Outcomes in the Randomized FAVORIT Ancillary Cognitive Trial.
Topics: Cognition; Cognition Disorders; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Longitudinal Studies; Male; Middle Aged; Neuropsychological Tests; North America; Postoperative Complications; Treatment Outcome; Vitamin B Complex | 2017 |
Rehydration during exercise prevents the increase of homocysteine concentrations.
Topics: Adult; Creatine; Creatinine; Cross-Over Studies; Drinking Water; Exercise; Fluid Therapy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Isotonic Solutions; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vitamin B 12; Young Adult | 2019 |
Effect of long-term low-dose folic acid supplementation on degree of total homocysteine-lowering: major effect modifiers.
Topics: Aged; China; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Genotype; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Smoking; Stroke | 2018 |
Effects of dietary supplementation with creatine on homocysteinemia and systemic microvascular endothelial function in individuals adhering to vegan diets.
Topics: Adult; Body Weights and Measures; Creatine; Diet, Vegan; Dietary Supplements; Endothelium, Vascular; Female; Folic Acid; Humans; Hyperhomocysteinemia; Iontophoresis; Laser-Doppler Flowmetry; Male; Middle Aged; Regional Blood Flow | 2019 |
Hyperhomocysteinaemia and chronic venous ulcers.
Topics: Aged; Aged, 80 and over; Chronic Disease; Cohort Studies; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Varicose Ulcer; Vitamin B Complex; Wound Healing | 2015 |
Effects of baked products enriched with n-3 fatty acids, folates, β-glucans, and tocopherol in patients with mild mixed hyperlipidemia.
Topics: beta-Glucans; Blood Glucose; Cardiovascular Diseases; Cholesterol; Chylomicrons; Cross-Over Studies; Diet; Dietary Supplements; Double-Blind Method; Energy Intake; Fasting; Fatty Acids, Omega-3; Female; Folic Acid; Humans; Hyperhomocysteinemia; Hyperlipidemia, Familial Combined; Insulin; Male; Meals; Middle Aged; Postprandial Period; Risk Factors; Tocopherols; Triglycerides | 2012 |
Homocysteine lowering by folate-rich diet or pharmacological supplementations in subjects with moderate hyperhomocysteinemia.
Topics: Adult; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Severity of Illness Index; Tetrahydrofolates; Vitamin B Complex | 2013 |
B-vitamin levels and genetics of hyperhomocysteinemia are not associated with arterial stiffness.
Topics: Aged; Aged, 80 and over; Blood Pressure; Body Mass Index; Creatinine; Cross-Sectional Studies; Double-Blind Method; Female; Folic Acid; Genotyping Techniques; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Methylmalonic Acid; Multivariate Analysis; Pulse Wave Analysis; Risk Factors; Vascular Stiffness; Vitamin B 12; Vitamin B Complex | 2014 |
B vitamin supplementation improves cognitive function in the middle aged and elderly with hyperhomocysteinemia.
Topics: Aged; Aged, 80 and over; Aging; China; Cognitive Dysfunction; Dietary Supplements; Elder Nutritional Physiological Phenomena; Female; Folic Acid; Follow-Up Studies; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nursing Homes; Prevalence; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12; Vitamin B 6 | 2016 |
Effect of folic acid supplementation on plasma homocysteine in obese children: a randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Body Mass Index; Child; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pediatric Obesity | 2014 |
Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Endpoint Determination; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Motor Activity; Netherlands; Osteoporotic Fractures; Risk Factors; Treatment Outcome; Vitamin B 12 | 2014 |
Effects of 2-year vitamin B12 and folic acid supplementation in hyperhomocysteinemic elderly on arterial stiffness and cardiovascular outcomes within the B-PROOF trial.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Blood Pressure; Cardiovascular Diseases; Carotid Intima-Media Thickness; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Pulse Wave Analysis; Risk Factors; Treatment Outcome; Vascular Stiffness; Vitamin B 12 | 2015 |
Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial.
Topics: Adult; Bangladesh; Biomarkers; Cohort Studies; Creatine; Dietary Supplements; Double-Blind Method; Down-Regulation; Female; Folic Acid; Glycine; Homocysteine; Humans; Hyperhomocysteinemia; Intention to Treat Analysis; Male; Middle Aged; Patient Dropouts; S-Adenosylhomocysteine; S-Adenosylmethionine | 2015 |
The C677T MTHFR genotypes influence the efficacy of B9 and B12 vitamins supplementation to lowering plasma total homocysteine in hemodialysis.
Topics: Adult; Biomarkers; Dietary Supplements; Down-Regulation; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Renal Dialysis; Time Factors; Treatment Outcome; Tunisia; Vitamin B 12; Vitamins | 2016 |
Effect of vitamin B12 and folic acid supplementation on biomarkers of endothelial function and inflammation among elderly individuals with hyperhomocysteinemia.
Topics: Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers; Dietary Supplements; Double-Blind Method; Drug Combinations; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Inflammation Mediators; Male; Netherlands; Time Factors; Treatment Outcome; Vitamin B 12 | 2016 |
[Effect of low-dose folate treatment on plasma homocystyeine and chemokine levels in patients with hyperhomocysteinemia].
Topics: Aged; Chemokines; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Treatment Outcome | 2008 |
Dysregulated RANK ligand/RANK axis in hyperhomocysteinemic subjects: effect of treatment with B-vitamins.
Topics: Adult; Arteritis; Cells, Cultured; Cytokines; Double-Blind Method; Extracellular Matrix; Female; Folic Acid; Humans; Hyperhomocysteinemia; Leukocytes, Mononuclear; Male; Matrix Metalloproteinase 9; Middle Aged; Placebos; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; RNA, Messenger; Up-Regulation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2009 |
A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Chi-Square Distribution; Cognition; Cognition Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Psychometrics; Risk Factors; Statistics, Nonparametric; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Dietary intervention with emphasis on folate intake reduces serum lipids but not plasma homocysteine levels in hyperlipidemic patients.
Topics: Adult; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Chi-Square Distribution; Diet; Diet Records; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Korea; Lipids; Male; Middle Aged; Vitamins | 2008 |
The effect of folic acid supplementation on carotid intima-media thickness in patients with cardiovascular risk: a randomized, placebo-controlled trial.
Topics: Aged; Carotid Artery Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; Risk Factors; Tunica Intima; Tunica Media; Ultrasonography; Vitamin B Complex | 2010 |
Effect of long-term homocysteine reduction with B vitamins on arterial wall inflammation assessed by fluorodeoxyglucose positron emission tomography: a randomised double-blind, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Aorta; Arteritis; Atherosclerosis; Brachial Artery; Carotid Arteries; Cross-Sectional Studies; Double-Blind Method; Drug Combinations; Female; Femoral Artery; Fluorodeoxyglucose F18; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Stroke; Time Factors; Treatment Outcome; Ultrasonography; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2009 |
Homocysteine-lowering therapy and stroke risk, severity, and disability: additional findings from the HOPE 2 trial.
Topics: Aged; Disability Evaluation; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; Severity of Illness Index; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamins | 2009 |
Influence of folic acid on plasma homocysteine levels & arterial endothelial function in patients with unstable angina.
Topics: Acute Coronary Syndrome; Adult; Aged; Angina, Unstable; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vasodilation; Vitamin B 12; Vitamin B Complex | 2009 |
Folic acid-based intervention in non-ST elevation acute coronary syndromes.
Topics: Acute Coronary Syndrome; Angina, Unstable; Disease-Free Survival; Electrocardiography; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Medication Adherence; Middle Aged; Myocardial Infarction; Vitamin B Complex | 2009 |
Cystatin C levels in plasma and peripheral blood mononuclear cells among hyperhomocysteinaemic subjects: effect of treatment with B-vitamins.
Topics: Adult; Aged; Cross-Sectional Studies; Cystatin C; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Hyperhomocysteinemia; Leukocytes, Mononuclear; Male; Middle Aged; Placebos; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2009 |
Efficacy of folate and vitamin B12 in lowering homocysteine concentrations in hemodialysis patients.
Topics: Administration, Oral; Adult; Aged; Biomarkers; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2009 |
Different doses of oral folic acid for homocysteine-lowering therapy in patients on hemodialysis: a randomized controlled trial.
Topics: Administration, Oral; Adult; Aged; Dose-Response Relationship, Drug; Female; Folic Acid; Follow-Up Studies; Hematinics; Humans; Hyperhomocysteinemia; Iran; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome | 2009 |
Homocysteine lowering with folic acid supplements in children: effects on blood pressure.
Topics: Adolescent; Age Factors; Blood Pressure; Child; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2010 |
Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; S-Adenosylhomocysteine; S-Adenosylmethionine; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life.
Topics: Age Factors; Antidepressive Agents; Biomarkers; Citalopram; Depression; Double-Blind Method; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Medication Adherence; Middle Aged; Psychiatric Status Rating Scales; Research Design; Severity of Illness Index; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Western Australia | 2010 |
Effect of physiological doses of oral vitamin B12 on plasma homocysteine: a randomized, placebo-controlled, double-blind trial in India.
Topics: Adult; Child; Dietary Supplements; Double-Blind Method; Family; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2010 |
Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomized controlled trial.
Topics: Aged; Diabetic Nephropathies; Double-Blind Method; Female; Folic Acid; Glomerular Filtration Rate; Humans; Hyperhomocysteinemia; Kidney; Male; Middle Aged; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2010 |
Randomized controlled trial of the effect of short-term coadministration of methylcobalamin and folate on serum ADMA concentration in patients receiving long-term hemodialysis.
Topics: Administration, Oral; Aged; Arginine; Cardiovascular Diseases; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors; Vitamin B 12; Vitamin B Complex | 2010 |
Pre-operative vitamin B infusion and prevention of nitrous oxide-induced homocysteine increase.
Topics: Adult; Anesthetics, Inhalation; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitrous Oxide; Preanesthetic Medication; Prospective Studies; Vitamin B 12; Vitamin B Complex | 2010 |
Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Morbidity; Myocardial Infarction; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2010 |
Hyperhomocysteinemia prevalence among patients with venous thromboembolism.
Topics: Adult; Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Risk Factors; Venous Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Effects of oral folate supplementation on serum total homocysteine and cholesterol levels in hyperhomocysteinemic children.
Topics: Child; Cholesterol; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B Complex | 2010 |
A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Hong Kong; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Patient Dropouts; Vitamin B 12; Vitamin B Complex | 2011 |
Effect of different doses of folic acid on serum homocysteine level in patients on hemodialysis.
Topics: Aged; Aged, 80 and over; Cross-Over Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 2011 |
Effect of 3 y of folic acid supplementation on the progression of carotid intima-media thickness and carotid arterial stiffness in older adults.
Topics: Aged; Atherosclerosis; Carotid Artery Diseases; Carotid Artery, Common; Dietary Supplements; Disease Progression; Double-Blind Method; Elasticity; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Netherlands; Risk Factors; Tunica Intima; Tunica Media; Ultrasonography | 2011 |
Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial.
Topics: Adult; Aged; Arteriosclerosis; Cardiovascular Diseases; Death, Sudden, Cardiac; Female; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Myocardial Infarction; Risk Factors; Risk Reduction Behavior; Stroke; Vitamin B Complex | 2011 |
Folic acid effects on s-adenosylmethionine, s-adenosylhomocysteine, and DNA methylation in patients with intermediate hyperhomocysteinemia.
Topics: Adult; Aged; Dietary Supplements; DNA Methylation; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B Complex | 2011 |
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause | 2012 |
MTHFR C677T and MTR A2756G polymorphisms and the homocysteine lowering efficacy of different doses of folic acid in hypertensive Chinese adults.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Antihypertensive Agents; China; Double-Blind Method; Enalapril; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2012 |
The effect of vitamin B supplementation on homocysteine metabolism and clinical state of patients with chronic epilepsy treated with carbamazepine and valproic acid.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dietary Supplements; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Valproic Acid; Vitamin B 12; Vitamin B Complex; Young Adult | 2012 |
Decreasing plasma endothelin-1 and unchanged plasma neopterin during folate supplementation in hyperhomocysteinemia.
Topics: Aged; Blood Platelets; Cyclic AMP; Cyclic GMP; Endothelin-1; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Neopterin; Vascular Diseases | 2002 |
Assessment of three levels of folic acid on serum folate and plasma homocysteine: a randomised placebo-controlled double-blind dietary intervention trial.
Topics: Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neural Tube Defects; Nutritional Requirements; Placebos; Vitamin B 12 | 2002 |
Reduction of plasma homocysteine by folic acid in children with chronic renal failure.
Topics: Adolescent; Child; Child, Preschool; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Kidney Failure, Chronic; Male | 2002 |
Coronary endothelial function in hyperhomocysteinemia: improvement after treatment with folic acid and cobalamin in patients with coronary artery disease.
Topics: Adult; Aged; Coronary Circulation; Coronary Disease; Coronary Vessels; Endothelium, Vascular; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Vitamin B 12 | 2002 |
Hyperhomocysteinemia in Japanese patients with convalescent stage ischemic stroke: effect of combined therapy with folic acid and mecobalamine.
Topics: Aged; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Hematinics; Homocystine; Humans; Hyperhomocysteinemia; Japan; Male; Middle Aged; Stroke; Treatment Outcome; Vitamin B 12 | 2002 |
Effect of folic acid therapy on serum homocysteine level in renal transplant recipients.
Topics: Adult; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male | 2002 |
Post-methionine-load hyperhomocysteinemia and increased lipoprotein(a) are associated with renal metabolic dysfunction: a hypothesis.
Topics: Apolipoproteins A; Creatinine; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Diseases; Lipoprotein(a); Male; Methionine; Middle Aged; Vitamin B 12 | 2002 |
The effect of B-vitamins on hyperhomocysteinemia in patients on antiepileptic drugs.
Topics: Adult; Anticonvulsants; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Methionine; Middle Aged; Pyridoxic Acid; Riboflavin; Selectins; Vascular Cell Adhesion Molecule-1; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2002 |
Distribution of plasma folate forms in hemodialysis patients receiving high daily doses of L-folinic or folic acid.
Topics: Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Dialysis | 2002 |
Hyperhomocysteinemia and endothelial function in young subjects: effects of vitamin supplementation.
Topics: Adolescent; Adult; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 6 | 2002 |
Effect of low doses of 5-methyltetrahydrofolate and folic acid on plasma homocysteine in healthy subjects with or without the 677C-->T polymorphism of methylenetetrahydrofolate reductase.
Topics: Adult; Aged; Double-Blind Method; Female; Folic Acid; Genotype; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Statistics, Nonparametric; Tetrahydrofolates; Time Factors | 2002 |
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins.
Topics: Aged; Analysis of Variance; Arginine; Arterial Occlusive Diseases; Double-Blind Method; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitric Oxide Synthase; Oxidative Stress; Peripheral Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamins | 2003 |
Effects of acute hyperhomocysteinemia on the neurovascular coupling mechanism in healthy young adults.
Topics: Acute Disease; Adult; Blood Flow Velocity; Brain; Cerebrovascular Circulation; Cross-Over Studies; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Photic Stimulation; Posterior Cerebral Artery; Reference Values; Systole; Ultrasonography, Doppler, Transcranial | 2003 |
Folic acid treatment reduces elevated plasma levels of asymmetric dimethylarginine in hyperhomocysteinaemic subjects.
Topics: Adult; Aged; Arginine; Biomarkers; Dietary Supplements; Enzyme Inhibitors; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitric Oxide Synthase | 2003 |
Homocysteine-lowering treatment with folic acid plus vitamin B6 lowers urinary albumin excretion but not plasma markers of endothelial function or C-reactive protein: further analysis of secondary end-points of a randomized clinical trial.
Topics: Adult; Albuminuria; Arteriosclerosis; Biomarkers; C-Reactive Protein; Endothelium; Folic Acid; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 6 | 2003 |
The effect of vitamin B12 on total plasma homocysteine concentration in folate-replete hemodialysis patients.
Topics: Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Renal Dialysis; Statistics, Nonparametric; Treatment Outcome; Vitamin B 12 | 2003 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
Topics: Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Linear Models; Male; Middle Aged; Parkinson Disease; Pyridoxal Phosphate; Risk Factors; Vitamin B 12; Vitamin B Complex | 2003 |
Effects of folic acid treatment on homocysteine levels and vascular disease in hemodialysis patients.
Topics: Aged; Cardiovascular Diseases; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Survival Rate | 2003 |
Folate treatment and unbalanced methylation and changes of allelic expression induced by hyperhomocysteinaemia in patients with uraemia.
Topics: Adult; Aged; Comorbidity; DNA Methylation; Folic Acid; Gene Expression; Heterozygote; Humans; Hyperhomocysteinemia; Insulin-Like Growth Factor II; Leukocytes; Male; Membrane Proteins; Middle Aged; Polymorphism, Genetic; R-SNARE Proteins; Renal Dialysis; Risk Factors; RNA, Long Noncoding; RNA, Untranslated; Uremia | 2003 |
Vitamin supplementation reduces the progression of atherosclerosis in hyperhomocysteinemic renal-transplant recipients.
Topics: Adult; Arteriosclerosis; Carotid Arteries; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Pyridoxine; Tunica Intima; Vitamin B 12 | 2003 |
Hyperhomocysteinaemia is not associated with increased levels of asymmetric dimethylarginine in patients with ischaemic heart disease.
Topics: Adult; Arginine; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Ischemia; Nitric Oxide Synthase; Pyridoxine; Vitamin B 12 | 2003 |
Fenofibrate-induced hyperhomocysteinemia may be prevented by folate co-administration.
Topics: Aged; Anticholesteremic Agents; Cross-Over Studies; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Indoles; Male; Middle Aged; Prospective Studies | 2003 |
Effect of folic acid on fenofibrate-induced elevation of homocysteine and cysteine.
Topics: Cholesterol; Creatinine; Cysteine; Female; Fenofibrate; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Prospective Studies; Statistics as Topic; Triglycerides; Uric Acid | 2003 |
Treatment of hyperhomocysteinemia after renal transplantation.
Topics: Adult; Aged; Creatinine; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Reproducibility of Results; Safety; Time Factors; Vitamin B 12 | 2003 |
Folic acid and vitamin E supplementation effects on homocysteinemia, endothelial function and plasma antioxidant capacity in young myocardial-infarction patients.
Topics: Adult; Antioxidants; Diagnostic Techniques and Procedures; Dietary Supplements; Drug Administration Schedule; Endothelium, Vascular; Female; Folic Acid; Gene Frequency; Genetic Markers; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Pharmacology, Clinical; Uric Acid; Vasodilation; Vitamin E | 2004 |
Folic acid does not improve endothelial function in healthy hyperhomocysteinaemic subjects.
Topics: Adult; Aged; Brachial Artery; Case-Control Studies; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Regional Blood Flow; Ultrasonography; Vasodilation | 2004 |
Randomized, placebo-controlled trial of intramuscular vitamin B12 for the treatment of hyperhomocysteinaemia in dialysis patients.
Topics: Adult; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intramuscular; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2003 |
Atrophic gastritis as a cause of hyperhomocysteinaemia.
Topics: Female; Folic Acid; Gastritis, Atrophic; Helicobacter Infections; Helicobacter pylori; Humans; Hyperhomocysteinemia; Malabsorption Syndromes; Male; Middle Aged; Odds Ratio; Regression Analysis; Risk Factors; Vitamin B 12 | 2004 |
Effect of homocysteine-lowering vitamin treatment on electrocardiography stress tests in a randomized, placebo-controlled trial: comparison between ST-segment changes and Athen QRS-score.
Topics: Coronary Artery Disease; Double-Blind Method; Electrocardiography; Exercise Test; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 6 | 2004 |
Effects of folic acid fortification and multivitamin therapy on homocysteine and vitamin B(12) status in cardiac transplant recipients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Canada; Cohort Studies; Dietary Supplements; Female; Ferredoxin-NADP Reductase; Folic Acid; Food, Fortified; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12; Vitamins | 2004 |
Comparative study of response to treatment with supraphysiologic doses of B-vitamins in hyperhomocysteinemic hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
The 5,10-methylenetetrahydrofolate reductase C677T polymorphism interacts with smoking to increase homocysteine.
Topics: Adult; Cohort Studies; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Hyperhomocysteinemia; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Probability; Risk Assessment; Smoking | 2004 |
[Study of the effect of medicinal product "STRESSEN" on blood levels of homocysteine in patients with current cardiovascular disease].
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Drug Combinations; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vitamin B 12 | 2004 |
[Comparison of treatment with STRESSEN and arginine glutamate on homocysteine blood levels].
Topics: Dipeptides; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Single-Blind Method; Vitamin B 12 | 2004 |
["STRESSEN" in the treatment of psycho-physical stress and hyperhomocysteinemia in patients with migraine without aura].
Topics: Adult; Aged; Drug Combinations; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Migraine without Aura; Stress, Physiological; Stress, Psychological; Surveys and Questionnaires; Vitamin B 12 | 2004 |
Folate therapy and in-stent restenosis after coronary stenting.
Topics: Aged; Coronary Angiography; Coronary Disease; Coronary Restenosis; Coronary Vessels; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stents; Treatment Failure; Vitamin B 12; Vitamin B 6 | 2004 |
Is there really a power shortage in clinical trials testing the "homocysteine hypothesis?".
Topics: Australia; Cohort Studies; Double-Blind Method; Edible Grain; Folic Acid; Food, Fortified; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Randomized Controlled Trials as Topic; Sample Size; Secondary Prevention; Stroke; Thrombophilia; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Cardiovascular Diseases; Cystathionine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Norway; Prospective Studies; Vitamin B 12; Vitamin B 6 | 2004 |
Effects of multivitamins and low-dose folic acid supplements on flow-mediated vasodilation and plasma homocysteine levels in older adults.
Topics: Aged; Aged, 80 and over; Brachial Artery; Dietary Supplements; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prospective Studies; Single-Blind Method; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamins | 2004 |
Creatine supplementation does not decrease total plasma homocysteine in chronic hemodialysis patients.
Topics: Aged; Aged, 80 and over; Creatine; Cross-Over Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Nutrition Assessment; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2004 |
Homocyst(e)ine-lowering therapy does not affect plasma asymmetrical dimethylarginine concentrations in patients with peripheral artery disease.
Topics: Aged; Arginine; Double-Blind Method; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Peripheral Vascular Diseases; Vitamin B Complex | 2005 |
The influence of folate and antioxidants on homocysteine levels and oxidative stress in patients with hyperlipidemia and hyperhomocysteinemia.
Topics: Adult; Aged; Antioxidants; Biomarkers; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress | 2005 |
[Hyperhomocysteinemia and treatment with antiepileptic drugs. Effects of different doses of folic acid].
Topics: Adult; Aged; Anticonvulsants; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2005 |
L-folic acid supplementation in healthy postmenopausal women: effect on homocysteine and glycolipid metabolism.
Topics: Blood Glucose; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cysteine; Energy Metabolism; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Middle Aged; Postmenopause; Risk Factors; Risk Reduction Behavior | 2005 |
Folic acid supplementation for 3 wk reduces pulse pressure and large artery stiffness independent of MTHFR genotype.
Topics: Adult; Blood Glucose; Blood Pressure; Cholesterol; Cross-Over Studies; Double-Blind Method; Folic Acid; Genotype; Hematinics; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Vascular Resistance | 2005 |
Plasma homocysteine and markers for oxidative stress and inflammation in patients with coronary artery disease--a prospective randomized study of vitamin supplementation.
Topics: Aged; Biomarkers; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Pyridoxine; Vitamin B 12; Vitamins | 2005 |
[Efficacy and safety of two vitamin supplement regimens on homocysteine levels in hemodialysis patients. Prospective, randomized clinical trial].
Topics: Aged; Aged, 80 and over; Cohort Studies; Diabetic Nephropathies; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
[Treatment of hyperhomocysteinemia and endothelial dysfunction in renal-transplant recipients with vitamin B].
Topics: Adult; Drug Therapy, Combination; Endothelium, Vascular; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
Homocysteine-lowering therapy and early progression of transplant vasculopathy: a prospective, randomized, IVUS-based study.
Topics: Adult; Cytomegalovirus Infections; Disease Progression; Female; Folic Acid; Heart Diseases; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Hyperplasia; Male; Middle Aged; Prospective Studies; Research Design; Risk Factors; Tetrahydrofolates; Time Factors; Ultrasonography; Vascular Diseases | 2005 |
Hyperhomocysteinemia in children treated with antiepileptic drugs is normalized by folic acid supplementation.
Topics: Anticonvulsants; Child; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Treatment Outcome; Vitamin B 12 | 2005 |
Efficacy of B vitamins in lowering homocysteine in older men: maximal effects for those with B12 deficiency and hyperhomocysteinemia.
Topics: Aged; Dietary Supplements; Double-Blind Method; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Placebos; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Determining factors of the response to hyperhomocysteinemia treatment in renal transplant patients.
Topics: Adult; Aged; Analysis of Variance; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; ROC Curve; Treatment Outcome; Vitamin B 12 | 2005 |
Preliminary results of the effect of treatment of hyperhomocysteinemia and its relationship with inflammation, coagulation status, and endothelial function after renal transplantation.
Topics: Adult; Aged; Biomarkers; Blood Coagulation; Blood Coagulation Disorders; Brachial Artery; Creatinine; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prospective Studies; Vitamin B 12 | 2005 |
Effects of short-term folic acid and/or riboflavin supplementation on serum folate and plasma total homocysteine concentrations in young Japanese male subjects.
Topics: Adult; Alanine Transaminase; Dietary Supplements; Double-Blind Method; Drug Interactions; Erythrocytes; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Riboflavin; Vitamin B Complex | 2006 |
Methylenetetrahydrofolate reductase polymorphisms and homocysteine-lowering effect of vitamin therapy in Singaporean stroke patients.
Topics: Aged; Coronary Artery Disease; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Middle Aged; Models, Statistical; Placebos; Polymorphism, Genetic; Regression Analysis; Risk Factors; Singapore; Stroke; Vitamin B 12; Vitamin B 6; Vitamins | 2006 |
Homocysteine-reducing strategies improve symptoms in chronic schizophrenic patients with hyperhomocysteinemia.
Topics: Adult; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Pyridoxine; Schizophrenia; Schizophrenic Psychology; Time Factors; Vitamin B 12; Vitamin B Complex | 2006 |
Homocysteine lowering with folic acid and B vitamins in vascular disease.
Topics: Aged; Cardiovascular Diseases; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Risk Factors; Stroke; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
Homocysteine lowering and cardiovascular events after acute myocardial infarction.
Topics: Adult; Aged; Aged, 80 and over; Death, Sudden, Cardiac; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Secondary Prevention; Stroke; Vitamin B 12; Vitamin B 6 | 2006 |
No effect of homocysteine-lowering therapy on vascular inflammation and haemostasis in peripheral arterial occlusive disease.
Topics: Aged; Arterial Occlusive Diseases; Biomarkers; Chronic Disease; Drug Therapy, Combination; Female; Folic Acid; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation Mediators; Male; Middle Aged; Patient Compliance; Peripheral Vascular Diseases; Vasculitis; Vitamin B Complex | 2006 |
No effect of B vitamins on ADMA levels in patients at increased cardiovascular risk.
Topics: Adolescent; Adult; Arginine; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Pyridoxine; Risk Factors; Time Factors; Treatment Failure; Vitamin B Complex | 2006 |
Folic acid 5 or 15 mg/d similarly reduces plasma homocysteine in patients with moderate-advanced chronic renal failure.
Topics: Aged; Double-Blind Method; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Middle Aged; Renal Replacement Therapy; Vitamin B Complex | 2006 |
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study.
Topics: Aged; Antiparkinson Agents; Canada; Catechols; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Placebo Effect; Treatment Outcome; United States; Vitamin B 12; Vitamins | 2006 |
A controlled trial of homocysteine lowering and cognitive performance.
Topics: Aged; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Psychological Tests; Vitamin B 12; Vitamin B Complex | 2006 |
Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Proportional Hazards Models; Pulmonary Embolism; Pyridoxine; Recurrence; Risk Factors; Thrombophilia; Treatment Failure; Venous Thrombosis; Vitamin B 12 | 2007 |
B-vitamin status and concentrations of homocysteine in Austrian omnivores, vegetarians and vegans.
Topics: Adult; Aged; Alcohol Drinking; Anthropometry; Aspartate Aminotransferases; Austria; Diet; Diet, Vegetarian; Feeding Behavior; Female; Folic Acid; Glutathione Reductase; Homocysteine; Humans; Hyperhomocysteinemia; Male; Meat; Middle Aged; Pyridoxal Phosphate; Pyridoxic Acid; Riboflavin; Riboflavin Deficiency; Surveys and Questionnaires; Thiamine; Transketolase; Vegetables; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2006 |
Effect of short-term folate and vitamin B supplementation on blood homocysteine level and carotid artery wall thickness in chronic hemodialysis patients.
Topics: Atherosclerosis; Carotid Arteries; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Treatment Outcome; Ultrasonography; Vitamin B 12; Vitamin B 6 | 2006 |
Effect of fortified spread on homocysteine concentration in apparently healthy volunteers.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
Homocysteine, MTHFR C677 T, vitamin B12, and folate levels in Thai children with ischemic stroke: a case-control study.
Topics: Adolescent; Child; Child, Preschool; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Ischemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Polymorphism, Single Nucleotide; Retrospective Studies; Risk Factors; Stroke; Thailand; Thrombosis; Vitamin B 12 | 2006 |
Oral vitamin B12 supplementation reduces plasma total homocysteine concentration in women in India.
Topics: Administration, Oral; Adult; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Middle Aged; Prevalence; Treatment Outcome; Vegetables; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2007 |
Folic acid therapy reduces plasma homocysteine levels and improves plasma antioxidant capacity in hemodialysis patients.
Topics: Cardiovascular Diseases; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hydrogen Peroxide; Hyperhomocysteinemia; Lipid Peroxidation; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Renal Dialysis; Time Factors; Vitamin B Complex | 2007 |
Uremic hyperhomocysteinemia: a randomized trial of folate treatment for the prevention of cardiovascular events.
Topics: Adult; Cardiovascular Diseases; Cause of Death; Double-Blind Method; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Survival Rate; Treatment Outcome; Uremia | 2007 |
The risk of recurrent cardiovascular events in patients with increased plasma homocysteine levels is reduced by short but not long-term therapy with folate and B vitamins.
Topics: Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Recurrence; Risk Factors; Time Factors; Treatment Outcome; Vitamin B Complex | 2007 |
Homocysteine-lowering therapy and risk for venous thromboembolism: a randomized trial.
Topics: Aged; Female; Folic Acid; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Prospective Studies; Pulmonary Embolism; Risk Factors; Thromboembolism; Venous Thrombosis; Vitamin B 12; Vitamin B 6 | 2007 |
The folic acid metabolite L-5-methyltetrahydrofolate effectively reduces total serum homocysteine level in orthotopic liver transplant recipients: a double-blind placebo-controlled study.
Topics: Chromatography, High Pressure Liquid; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Transplantation; Male; Middle Aged; Prospective Studies; Tetrahydrofolates; Treatment Outcome | 2008 |
Randomized clinical trial of homocysteine level lowering therapy and fractures.
Topics: Aged; Cardiovascular Diseases; Drug Therapy, Combination; Female; Folic Acid; Fractures, Bone; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Proportional Hazards Models; Pyridoxine; Risk Factors; Treatment Outcome; Vitamin B 12 | 2007 |
Should hyperhomocysteinemia be treated in patients with atherosclerotic disease?
Topics: Arteriosclerosis; Disease Susceptibility; Folic Acid; Humans; Hyperhomocysteinemia; Prognosis; Risk Assessment; Risk Factors; Treatment Outcome | 2007 |
Treatment of hyperhomocysteinemia and endothelial dysfunction in renal transplant recipients with B vitamins in the Chinese population.
Topics: Adult; Asian People; Case-Control Studies; Endothelium, Vascular; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Treatment Outcome; Ultrasonography, Interventional; Vascular Diseases; Vasodilation; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Effects of folic acid and N-acetylcysteine on plasma homocysteine levels and endothelial function in patients with coronary artery disease.
Topics: Acetylcysteine; Administration, Oral; Aged; Coronary Artery Disease; Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2007 |
Effect of folic acid in women with and without insulin resistance who have hyperhomocysteinemic polycystic ovary syndrome.
Topics: Adolescent; Adult; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Insulin Resistance; Polycystic Ovary Syndrome; Prospective Studies; Vitamin B Complex | 2008 |
Effect of nitrous oxide on plasma homocysteine and folate in patients undergoing major surgery.
Topics: Adult; Aged; Anesthetics, Inhalation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intraoperative Period; Male; Middle Aged; Nitrous Oxide; Postoperative Complications; Risk Assessment; Risk Factors | 2008 |
Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients.
Topics: Adult; Betaine; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Methylation; Middle Aged; Renal Dialysis; Time Factors; Treatment Outcome | 1999 |
Plasma total homocysteine response to oral doses of folic acid and pyridoxine hydrochloride (vitamin B6) in healthy individuals. Oral doses of vitamin B6 reduce concentrations of serum folate.
Topics: Administration, Oral; Adult; Cholesterol; Cysteine; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Middle Aged; Norway; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Vitamin B 12 | 1999 |
Hyperhomocysteinemia in high-aged subjects: relation of B-vitamins, folic acid, renal function and the methylenetetrahydrofolate reductase mutation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Regression Analysis; Risk Assessment; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 1999 |
Serum homocysteine increases after therapy with fenofibrate or bezafibrate.
Topics: Adult; Bezafibrate; Chromatography, High Pressure Liquid; Fenofibrate; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Hypertriglyceridemia; Hypolipidemic Agents; Male; Middle Aged; Pilot Projects; Pyridoxine; Vitamin B 12 | 1999 |
Variability of fasting and post-methionine plasma homocysteine levels in normo- and hyperhomocysteinaemic individuals.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Analysis of Variance; Fasting; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases; Statistics, Nonparametric | 1999 |
Treatment of hyperhomocysteinemia in children on dialysis by folic acid.
Topics: Child; Child, Preschool; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Peritoneal Dialysis; Renal Dialysis | 1999 |
Folic acid improves arterial endothelial function in adults with hyperhomocystinemia.
Topics: Administration, Oral; Adult; Aged; Arteriosclerosis; Brachial Artery; Cholesterol; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Observer Variation; Treatment Outcome; Ultrasonography; Vasodilation | 1999 |
Enhanced reduction of fasting total homocysteine levels with supraphysiological versus standard multivitamin dose folic acid supplementation in renal transplant recipients.
Topics: Adult; Fasting; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Logistic Models; Male; Middle Aged; Postoperative Complications; Renal Dialysis; Renal Insufficiency | 1999 |
Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial.
Topics: Blood Pressure; Coronary Artery Disease; Family; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxine; Risk Factors | 2000 |
Low-dose folic acid supplementation does not influence plasma methionine concentrations in young non-pregnant women.
Topics: Adolescent; Adult; Contraceptives, Oral; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Vitamin B 12 | 1999 |
Effect of high dose folic acid therapy on hyperhomocysteinemia in hemodialysis patients: results of the Vienna multicenter study.
Topics: Analysis of Variance; Chi-Square Distribution; Double-Blind Method; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Renal Dialysis; Treatment Outcome | 2000 |
Dietary strategies for lowering homocysteine concentrations.
Topics: Adult; Aged; Blood Glucose; Body Weight; Diet; Dietary Supplements; Edible Grain; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Lipoproteins; Male; Middle Aged; Vitamin B 12 | 2000 |
Treatment of mild hyperhomocysteinemia in renal transplant recipients versus hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Dietary Supplements; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Renal Dialysis; Vitamin B Complex | 2000 |
Controlled comparison of L-5-methyltetrahydrofolate versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Dialysis; Tetrahydrofolates; Treatment Failure | 2000 |
A controlled trial of the effect of folate supplements on homocysteine, lipids and hemorheology in end-stage renal disease.
Topics: Adult; Aged; Arteriosclerosis; Double-Blind Method; Female; Folic Acid; Hemorheology; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipids; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Risk Factors | 2000 |
Hyperhomocysteinemia in hemodialysis patients: effects of 12-month supplementation with hydrosoluble vitamins.
Topics: Aged; Cohort Studies; Female; Folic Acid; Follow-Up Studies; Genotype; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Renal Dialysis; Solubility; Vitamin B Complex | 2000 |
Folic acid in endothelial function in familial hypercholesterolemia.
Topics: Cross-Over Studies; Folic Acid; Humans; Hyperhomocysteinemia | 2000 |
Homocysteine and venous thrombosis: outline of a vitamin intervention trial.
Topics: Adult; Aged; Aged, 80 and over; Comorbidity; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Netherlands; Prospective Studies; Pulmonary Embolism; Pyridoxine; Retrospective Studies; Secondary Prevention; Thrombophilia; Thrombophlebitis; Treatment Outcome; Ultrasonography; Venous Thrombosis; Vitamin B 12 | 2000 |
Rapid communication: L-folinic acid versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leucovorin; Male; Middle Aged; Renal Dialysis; Treatment Outcome | 2001 |
Plasma homocysteine concentrations in the acute and convalescent periods of atherothrombotic stroke.
Topics: Acute Disease; Adult; Aged; Arteriosclerosis; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Convalescence; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Lipids; Male; Middle Aged; Regression Analysis; Risk Factors; Scotland; Stroke; Stroke Rehabilitation; Tomography, X-Ray Computed; Vitamin B 12 | 2001 |
Hyperhomocysteinemia and oxidative stress in ischemic stroke.
Topics: Aged; Aged, 80 and over; Aging; Ascorbic Acid; Chromatography, High Pressure Liquid; Female; Folic Acid; Humans; Hyperhomocysteinemia; Lipid Peroxides; Male; Nitric Oxide; Oxidative Stress; Predictive Value of Tests; Stroke; Vitamin B 12 | 2001 |
Treatment of hyperhomocysteinemia in hemodialysis patients and renal transplant recipients.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Renal Dialysis; Tetrahydrofolates | 2001 |
Oral vitamin B(12) and high-dose folic acid in hemodialysis patients with hyper-homocyst(e)inemia.
Topics: Administration, Oral; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Dialysis; Vitamin B 12 | 2001 |
Efficacy of folinic versus folic acid for the correction of hyperhomocysteinemia in hemodialysis patients.
Topics: Double-Blind Method; Drug Administration Schedule; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Leucovorin; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Renal Dialysis; Treatment Outcome; Vitamin B 12 | 2001 |
Homocysteine lowering effect of different multivitamin preparations in patients with end-stage renal disease.
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Pyridoxine; Renal Dialysis; Vitamin B 12 | 2001 |
Homocysteine--a treatable risk factor for allograft vascular disease after heart transplantation?
Topics: Aged; Cohort Studies; Cyclosporine; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Heart Transplantation; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Pyridoxine; Risk Factors; Transplantation, Homologous; Vitamin B 6 Deficiency | 2001 |
Homocysteine levels in patients treated with lipid apheresis: effect of a vitamin therapy.
Topics: Adult; Cystathionine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipoproteinemia Type II; Lipids; Male; Vitamin B 12; Vitamin B 6 | 2001 |
An MTHFR variant, homocysteine, and cardiovascular comorbidity in renal disease.
Topics: Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Ethnicity; Female; Folic Acid; Genotype; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Peritoneal Dialysis; Pyridoxine; Renal Dialysis; Risk Factors; Sex Factors; Vitamin B 12 | 2001 |
Long-term homocysteine-lowering treatment with folic acid plus pyridoxine is associated with decreased blood pressure but not with improved brachial artery endothelium-dependent vasodilation or carotid artery stiffness: a 2-year, randomized, placebo-contr
Topics: Adult; Blood Pressure; Brachial Artery; Carotid Arteries; Drug Therapy, Combination; Elasticity; Endothelium, Vascular; Female; Folic Acid; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pyridoxine; Vasodilation | 2001 |
Decreased rate of coronary restenosis after lowering of plasma homocysteine levels.
Topics: Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease-Free Survival; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Pyridoxine; Vitamin B 12 | 2001 |
5,10-Methylenetetrahydrofolate reductase genotype determines the plasma homocysteine-lowering effect of supplementation with 5-methyltetrahydrofolate or folic acid in healthy young women.
Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Folic Acid; Genotype; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Tetrahydrofolates | 2002 |
Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure.
Topics: Aged; Betaine; Cross-Over Studies; Drug Therapy, Combination; Fasting; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipids; Male; Methionine; Middle Aged; Pyridoxine; Sarcosine | 2002 |
Treatment of hyperhomocysteinemia with folic acid reduces oxidative stress in renal transplant recipients.
Topics: Adult; Antioxidants; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Oxidative Stress; Postoperative Complications; Time Factors | 2002 |
Hyperhomocysteinaemia therapy in haemodialysis patients: folinic versus folic acid in combination with vitamin B6 and B12.
Topics: Administration, Oral; Aged; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Injections, Intravenous; Leucovorin; Male; Middle Aged; Prospective Studies; Renal Dialysis; Time Factors; Vitamin B 12; Vitamin B 6 | 2002 |
Long-term improvement in homocysteine levels and arterial endothelial function after 1-year folic acid supplementation.
Topics: Adult; Aged; Arteriosclerosis; Endothelium, Vascular; Female; Folic Acid; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Multivariate Analysis; Ultrasonography; Vasodilation | 2002 |
Hydroxocobalamin reduces hyperhomocysteinemia in end-stage renal disease.
Topics: Aged; Female; Folic Acid; Homocysteine; Humans; Hydroxocobalamin; Hyperhomocysteinemia; Injections, Subcutaneous; Kidney Failure, Chronic; Male; Methylmalonic Acid; Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome; Vitamin B 12 | 2002 |
774 other study(ies) available for folic acid and Hyperhomocysteinemia
| Article | Year |
|---|---|
Prevalence of hyperhomocysteinemia (HHcy) and its major determinants among hypertensive patients over 35 years of age.
Topics: Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Prevalence; Risk Factors; Vitamin B 12 | 2022 |
The prevalence and clinical relevance of hyperhomocysteinemia suggesting vitamin B12 deficiency in presumed healthy infants.
Topics: Folic Acid; Humans; Hyperhomocysteinemia; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Combining genetic risk score with artificial neural network to predict the efficacy of folic acid therapy to hyperhomocysteinemia.
Topics: Aged; Algorithms; Female; Folic Acid; Genetic Markers; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Male; Neural Networks, Computer; Prospective Studies; Risk Factors; Treatment Outcome | 2021 |
New Evidence for Homocysteine Lowering for Management of Treatment-Resistant Hypertension.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Vitamin B Complex | 2022 |
Using the optimal method-explained variance weighted genetic risk score to predict the efficacy of folic acid therapy to hyperhomocysteinemia.
Topics: Folic Acid; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors | 2022 |
Commentary on Severe Hyperhomocysteinemia in a Patient with Parkinson Disease.
Topics: Folic Acid; Humans; Hyperhomocysteinemia; Parkinson Disease; Vitamin B 12 | 2022 |
RBC Folate and Serum Folate, Vitamin B-12, and Homocysteine in Chinese Couples Prepregnancy in the Shanghai Preconception Cohort.
Topics: Biomarkers; China; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Vitamin B12 and chronic kidney disease.
Topics: Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Renal Insufficiency, Chronic; Vitamin B 12 | 2022 |
Fetal hyperhomocysteinemia is associated with placental inflammation and early breakdown of maternal-fetal tolerance in pre-term birth.
Topics: Biomarkers; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Placenta; Pregnancy; Premature Birth; Term Birth; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vitamin B 12 | 2022 |
Vitamin B
Topics: Animals; Fatty Acids; Fibrosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Qa-SNARE Proteins; Vitamin B 12; Vitamins | 2022 |
Relationships of Serum Homocysteine, Vitamin B
Topics: Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Rosacea; Vitamin B 12; Vitamins | 2022 |
Proton pump inhibitor use and its effect on vitamin B12 and homocysteine levels among men and women: A large cross-sectional study.
Topics: Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Proton Pump Inhibitors; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Hyperhomocysteinemia in acute hepatic porphyria (AHP) and implications for treatment with givosiran.
Topics: Clinical Trials as Topic; Cystathionine beta-Synthase; Folic Acid; Heme; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Porphyrias, Hepatic; Pyridoxine; RNA, Small Interfering; Sulfur; Vitamin B 6 | 2022 |
Hyperhomocysteinemia Promotes Cardiac Hypertrophy in Hypertension.
Topics: Animals; Calcineurin; Cardiomegaly; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Mice; Myocytes, Cardiac; NFATC Transcription Factors; Rats; Retrospective Studies | 2022 |
Elevated homocysteine activates unfolded protein responses and causes aberrant trophoblast differentiation and mouse blastocyst development.
Topics: Animals; Blastocyst; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mice; Placenta; Pregnancy; Trophoblasts; Unfolded Protein Response; Vitamins | 2022 |
Serum Homocysteine, Vitamin B12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia.
Topics: Alzheimer Disease; Cognitive Dysfunction; Dementia, Vascular; Folic Acid; Frontotemporal Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2022 |
Distribution and Determinants of Plasma Homocysteine Levels in a Preconception Population: A Retrospective Single-Center Study.
Topics: China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Retrospective Studies | 2022 |
Elevated homocysteine levels: What inborn errors of metabolism might we be missing?
Topics: Adult; Female; Folic Acid; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Metabolism, Inborn Errors; Retrospective Studies; Vitamin B 12 | 2023 |
Vitamin B12 deficiency may play an etiological role in atrophic glossitis and its grading: A clinical case-control study.
Topics: Anemia; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Ferritins; Folic Acid; Glossitis; Hematinics; Hemoglobins; Humans; Hyperhomocysteinemia; Parietal Cells, Gastric; Tongue; Vitamin B 12; Vitamin B 12 Deficiency | 2022 |
Hyperhomocysteinemia in men and women of married couples with reproductive disorders. What is the difference?
Topics: Female; Folic Acid; Genotype; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Pregnancy; Reproduction; Vitamin B 12 | 2023 |
The role of the deficiency of vitamin B12 and folic acid on homocysteinemia in children with Turner syndrome.
Topics: Child; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Turner Syndrome; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
Topics: Adult; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Prospective Studies; Republic of Korea; Risk Factors | 2023 |
A Potential Strategy for Atherosclerosis Prevention in Modernizing China - Hyperhomocysteinemia, MTHFR C677T Polymorphism and Air Pollution (PM2.5) on Atherogenesis in Chinese Adults.
Topics: Air Pollution; Atherosclerosis; Carotid Intima-Media Thickness; East Asian People; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Particulate Matter | 2023 |
Cerebral venous thrombosis with hyperhomocysteinemia due to loss of heterozygosity at methylenetetrahydrofolate reductase (MTHFR) locus: a case report.
Topics: Adolescent; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Loss of Heterozygosity; Methylenetetrahydrofolate Reductase (NADPH2); Venous Thrombosis | 2023 |
Ischaemic stroke with multi-focal venous and arterial thrombosis due to hyperhomocysteinemia: anabolic androgenic steroid use and MTHFR c.667 C > T variant - a case report.
Topics: Anabolic Androgenic Steroids; Brain Ischemia; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Ischemic Stroke; Male; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Stroke; Thrombosis; Vitamin B 12 | 2023 |
Dapagliflozin's effect on serum homocysteine in patients with hypertension complicated with insulin resistance.
Topics: Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin Resistance; Retrospective Studies | 2023 |
Folic acid enhances the cardiovascular protective effect of amlodipine in renal hypertensive rats with elevated homocysteine.
Topics: Amlodipine; Animals; Endothelial Cells; Folic Acid; Homocysteine; Hyperhomocysteinemia; Hypertension; Kidney; Rats | 2023 |
Hyperhomocysteinemia, High Altitude, and Varied Retinal Manifestations: Unravelling the Enigma.
Topics: Altitude; Folic Acid; Humans; Hyperhomocysteinemia; Retinal Artery Occlusion; Retinal Vein Occlusion | 2023 |
Childhood Neurological Disorders With Hyperhomocystinemia: A Case-Based Review.
Topics: Child; Folic Acid; Humans; Hyperhomocysteinemia; Nervous System Diseases | 2023 |
A Cell-Free Biosensor for Assessment of Hyperhomocysteinemia.
Topics: Cross-Sectional Studies; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Multimorbidity; Vitamin B 12 | 2023 |
Anemia, hematinic deficiencies, and gastric parietal cell antibody positivity in atrophic glossitis patients with or without hyperhomocysteinemia.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Count; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Taiwan; Vitamin B 12; Young Adult | 2020 |
Association between BHMT and CBS gene promoter methylation with the efficacy of folic acid therapy in patients with hyperhomocysteinemia.
Topics: Aged; Betaine-Homocysteine S-Methyltransferase; Cystathionine beta-Synthase; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methylation; Middle Aged; Promoter Regions, Genetic; Prospective Studies | 2019 |
Serum total homocysteine level in Iraqi woman with unexplained recurrent Miscarriage.
Topics: Abortion, Habitual; Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; ROC Curve; Sensitivity and Specificity; Vitamin B 12 | 2019 |
Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with iron deficiency.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Iron-Deficiency; Anemia, Pernicious; Autoantibodies; Case-Control Studies; Comorbidity; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Glossitis; Hematinics; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2020 |
Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with vitamin B12 deficiency.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Autoantibodies; Case-Control Studies; Comorbidity; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Glossitis; Hematinics; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Hyperhomocysteinemia induced locked-in syndrome in a young adult due to folic acid deficiency.
Topics: Adolescent; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Locked-In Syndrome; Male; Vitamin B 12; Young Adult | 2021 |
Comment on 'The effects of isotretinoin therapy on serum homocysteine, folate and vitamin B12 levels in patients with acne': may retinoids be useful to treat hyperhomocysteinemia found in patients affected by hidradenitis suppurativa?
Topics: Acne Vulgaris; Folic Acid; Hidradenitis Suppurativa; Homocysteine; Humans; Hyperhomocysteinemia; Isotretinoin; Retinoids; Vitamin B 12 | 2020 |
Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in 884 patients with burning mouth syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia; Autoantibodies; Burning Mouth Syndrome; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2020 |
Genetic and epigenetic regulation of BHMT is associated with folate therapy efficacy in hyperhomocysteinaemia.
Topics: Aged; Betaine-Homocysteine S-Methyltransferase; Cohort Studies; Epigenesis, Genetic; Female; Folic Acid; Gene Expression Regulation; Genotype; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies | 2019 |
CBS gene polymorphism and promoter methylation-mediating effects on the efficacy of folate therapy in patients with hyperhomocysteinemia.
Topics: Adult; Aged; Alleles; Biomarkers; Cystathionine beta-Synthase; DNA Methylation; Female; Folic Acid; Gene Frequency; Genotype; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Pharmacogenetics; Pharmacogenomic Variants; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Treatment Outcome | 2020 |
A homozygous deletion in the SLC19A1 gene as a cause of folate-dependent recurrent megaloblastic anemia.
Topics: Adolescent; Anemia, Megaloblastic; Cells, Cultured; Clone Cells; CRISPR-Cas Systems; Exome Sequencing; Folic Acid; Frameshift Mutation; Gene Knockout Techniques; Homozygote; Humans; Hyperhomocysteinemia; K562 Cells; Male; Recurrence; Sequence Deletion; Sodium-Hydrogen Exchanger 1; Vitamin B 12 | 2020 |
Discrete laboratory and morphometric markers of atherosclerotic lesions of lower extremity vessels.
Topics: Atherosclerosis; Endothelial Cells; Folic Acid; Humans; Hyperhomocysteinemia; Lower Extremity; Middle Aged | 2020 |
Identifying gene-environment interactions on the efficacy of folic acid therapy for hyperhomocysteinemia based on prediction model.
Topics: Aged; Algorithms; Coronary Disease; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Machine Learning; Male; Middle Aged; Models, Theoretical; Polymorphism, Single Nucleotide; Prospective Studies; Risk Factors; Stroke; Treatment Failure; Treatment Outcome | 2020 |
Association between gene promoter methylation of the one-carbon metabolism pathway and serum folate among patients with hyperhomocysteinemia.
Topics: Carbon; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylation; Promoter Regions, Genetic | 2020 |
Low doses of folic acid can reduce hyperhomocysteinemia-induced glomerular injury in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Drug Evaluation, Preclinical; Folic Acid; Homocysteine; Hyperhomocysteinemia; Hypertension; Kidney Cortex; Kidney Diseases; Male; Malondialdehyde; Membrane Proteins; NADPH Oxidase 2; NADPH Oxidase 4; Podocytes; Random Allocation; Rats, Inbred SHR; Superoxide Dismutase; Vitamin B Complex | 2020 |
Distribution characteristics of circulating homocysteine and folate and related factors in agriculture, stock-raising and urban populations: a cross-sectional survey.
Topics: Agriculture; Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2021 |
Hyperhomocysteinemia is Associated with Inflammation, Bone Resorption, Vitamin B12 and Folate Deficiency and MTHFR C677T Polymorphism in Postmenopausal Women with Decreased Bone Mineral Density.
Topics: Bone Density; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osteitis; Osteoporosis, Postmenopausal; Oxidoreductases; Polymorphism, Genetic; Postmenopause; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Hyperhomocysteinemia and Low Folate and Vitamin B12 Are Associated with Vascular Dysfunction and Impaired Nitric Oxide Sensitivity in Morbidly Obese Patients.
Topics: Adult; Alcohol Drinking; Arterioles; Bariatric Surgery; Brachial Artery; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nitric Oxide; Nutritional Status; Obesity, Morbid; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Hyperhomocysteinemia: an instigating factor for periodontal disease.
Topics: Animals; Cystathionine beta-Synthase; Disease Models, Animal; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mice; Mice, Transgenic; Oxidative Stress; Periodontitis; Periodontium | 2021 |
Which one, gastric parietal cell antibody positivity or hyperhomocysteinemia, is a better biomarker to predict oral mucosal disease patients with vitamin B12 deficiency?
Topics: Biomarkers; Case-Control Studies; Folic Acid; Folic Acid Deficiency; Glossitis; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Parietal Cells, Gastric; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Prevalence of hyperhomocysteinaemia, selected determinants and relation to hypertension severity in Northern-Nigerian hypertensives: the ABU homocysteine survey.
Topics: Adult; Blood Pressure; Blood Pressure Determination; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Nigeria; Prevalence; Risk Factors; Surveys and Questionnaires | 2020 |
Anemia, hematinic deficiencies, and hyperhomocysteinemia in gastric parietal cell antibody-positive and -negative burning mouth syndrome patients.
Topics: Anemia; Burning Mouth Syndrome; Folic Acid; Folic Acid Deficiency; Glossitis; Hematinics; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Parietal Cells, Gastric; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
The effect of folate and VitB
Topics: Aged; Cognition; Cognitive Dysfunction; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Treatment Outcome; Vitamin B 12 | 2020 |
The recent effects of small dose of folic acid on lipoprotein-associated phospholipase A2 and systolic blood pressure variability in coronary heart disease patients with hyperhomocysteinemia: A single-center prospective cohort study.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Age Factors; Aged; Apolipoproteins A; Blood Pressure; Coronary Disease; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Sex Factors | 2020 |
Relationship between plasma homocysteine and blood pressure in hypertensive Northern-Nigerians.
Topics: Biomarkers; Blood Pressure; Blood Pressure Determination; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Risk Factors | 2020 |
Hyperhomocysteinemia and Dementia Associated With Severe Cortical Atrophy, but No Amyloid Burden.
Topics: Aged; Alzheimer Disease; Atrophy; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 2022 |
POSITIVE EFFECT OF BETAINE-ARGININE SUPPLEMENT ON IMPROVED HYPERHOMOCYSTEINEMIA TREATMENT IN MARRIED COUPLES WITH REPRODUCTIVE DISORDERS.
Topics: Arginine; Betaine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12 | 2020 |
Hyperhomocysteinemia and low folate levels as the only risk factors in pseudo-Foster Kennedy syndrome.
Topics: Folic Acid; Humans; Hyperhomocysteinemia; Optic Nerve Diseases; Risk Factors | 2021 |
Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson's disease.
Topics: Aged; Bacteria; Case-Control Studies; Databases, Genetic; Dysbiosis; Folic Acid; Folic Acid Deficiency; Gastrointestinal Microbiome; Homocysteine; Humans; Hyperhomocysteinemia; Intestines; Male; Metabolome; Metabolomics; Metagenome; Metagenomics; Middle Aged; Mucins; Parkinson Disease; Polysaccharides; Severity of Illness Index | 2021 |
Folic acid as placebo in controlled clinical trials of hydroxychloroquine prophylaxis in COVID-19: Is it scientifically justifiable?
Topics: Angiotensin-Converting Enzyme 2; COVID-19; COVID-19 Drug Treatment; Folic Acid; Humans; Hydroxychloroquine; Hyperhomocysteinemia; Hypertension, Pulmonary; Methylenetetrahydrofolate Reductase (NADPH2); Models, Theoretical; Nitric Oxide Synthase Type III; Placebos; Protein Binding; Randomized Controlled Trials as Topic; Research Design | 2021 |
Cardiovascular manifestations of intermediate and major hyperhomocysteinemia due to vitamin B12 and folate deficiency and/or inherited disorders of one-carbon metabolism: a 3.5-year retrospective cross-sectional study of consecutive patients.
Topics: Adult; Cardiovascular Diseases; Child, Preschool; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Middle Aged; Retrospective Studies; Vitamin B 12 | 2021 |
Hyperhomocysteinemia in patients with cardiovascular manifestations: to treat or not to treat.
Topics: Carbon; Cross-Sectional Studies; Folic Acid; Humans; Hyperhomocysteinemia; Retrospective Studies; Risk Factors; Vitamin B 12 | 2021 |
Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Topics: Acetylgalactosamine; Adult; Arginine; Cystathionine beta-Synthase; Female; Folic Acid; Heme; Homeostasis; Homocysteine; Homocystinuria; Humans; Hydroxymethylbilane Synthase; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Porphyria, Acute Intermittent; Pyridoxal Phosphate; Pyrrolidines; Young Adult | 2021 |
Vitamin B12 deficiency and anemia in 140 Taiwanese female lacto-vegetarians.
Topics: Anemia; Anemia, Iron-Deficiency; Autoantibodies; Erythrocyte Indices; Female; Folic Acid; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Parietal Cells, Gastric; Vegetarians; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Hyperhomocysteinemia-related serum metabolome alterations not normalized by short-term folic acid treatment.
Topics: Adolescent; Adult; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Metabolome; Vitamin B 12; Young Adult | 2021 |
Pernicious anaemia: cause of recurrent cerebral venous thrombosis.
Topics: Anemia, Pernicious; Folic Acid; Humans; Hyperhomocysteinemia; Venous Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2021 |
Low Dose of Folic Acid Can Ameliorate Hyperhomocysteinemia-Induced Cardiac Fibrosis and Diastolic Dysfunction in Spontaneously Hypertensive Rats.
Topics: Animals; Diastole; Drug Evaluation, Preclinical; Fibrosis; Folic Acid; Heart; Heart Diseases; Hematinics; Hyperhomocysteinemia; Hypertension; Male; Myocardium; Random Allocation; Rats, Inbred SHR | 2021 |
A study of hyperhomocysteinemia in cerebral venous sinus thrombosis.
Topics: Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; India; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Sinus Thrombosis, Intracranial; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Higher serum homocysteine level and frequency of hyperhomocysteinemia in carcinoembryonic antigen-positive or squamous cell carcinoma-antigen-positive oral leukoplakia patients.
Topics: Antigens, Neoplasm; Autoantibodies; Carcinoembryonic Antigen; Erythrocyte Indices; Folic Acid; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Leukoplakia, Oral; Parietal Cells, Gastric; Serpins; Vitamin B 12 | 2021 |
Hyperhomocysteinemia in patients with acute porphyrias: a possible effect of ALAS1 modulation by siRNAm therapy and its control by vitamin supplementation.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Porphyria, Acute Intermittent; Vitamin B 12; Vitamins | 2021 |
The protective mechanism of folic acid on hyperhomocysteinemia-related arterial injury in spontaneously hypertensive rats: Folic acid against arterial inflammation.
Topics: Animals; Arteritis; Folic Acid; Hyperhomocysteinemia; Hypertension; Interleukin-6; Malondialdehyde; NF-kappa B; Rats; Rats, Inbred SHR; Superoxide Dismutase | 2022 |
Insufficient S-Sulfhydration of Methylenetetrahydrofolate Reductase Contributes to the Progress of Hyperhomocysteinemia.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidation-Reduction; Vitamin B 12 | 2022 |
An Analysis of Transcobalamin II Gene Polymorphisms and Serum Levels of Homocysteine, Folate and Vitamin B12 in Chinese Patients with Crohn's Disease.
Topics: Adult; Asian People; Case-Control Studies; Crohn Disease; Female; Folic Acid; Genetic Association Studies; Haplotypes; Homocysteine; Humans; Hyperhomocysteinemia; Male; Polymorphism, Single Nucleotide; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2017 |
The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations.
Topics: Abortion, Habitual; Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Pregnancy; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2017 |
An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Sequence; Cells, Cultured; Exons; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylation; Models, Molecular; Pregnancy; Pregnancy Complications; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Deletion; Spinal Dysraphism; Young Adult | 2017 |
The Hydrogen Sulfide-Vitamin B12-Folic Acid Axis: An Intriguing Issue in Chronic Kidney Disease. A Comment on Toohey JI: "Possible Involvement of Hydrosulfide in B12-Dependent Methyl Group Transfer". Molecules 2017, 22, 582, pii: E582.
Topics: Folic Acid; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Renal Insufficiency, Chronic; Vitamin B 12 | 2017 |
Venous thromboembolism and hyperhomocysteinemia as first manifestation of pernicious anemia: a case series.
Topics: Adult; Anemia, Pernicious; Antibodies; Anticoagulants; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Parietal Cells, Gastric; Treatment Outcome; Venous Thromboembolism; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2017 |
Hyperhomocysteinemia as a Risk Factor for Saccular Intracranial Aneurysm: A Cohort Study in a Chinese Han Population.
Topics: Adult; Aged; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Intracranial Aneurysm; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Prospective Studies; Protective Factors; Risk Factors; Up-Regulation; Vitamin B 12 | 2017 |
Interplay between 3'-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke.
Topics: 3' Untranslated Regions; Aged; Brain Ischemia; Case-Control Studies; Female; Folic Acid; Gene Expression; Gene-Environment Interaction; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; Stroke | 2017 |
Homocysteine concentrations in the cognitive progression of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition; Disease Progression; Female; Folic Acid; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Mental Status and Dementia Tests; Neuropsychological Tests; Nutrition Assessment; Nutritional Status; Surveys and Questionnaires; Time Factors; Up-Regulation; Vitamin B 12 | 2017 |
Vitamin Status and the Development of Postoperative Cognitive Decline in Elderly Surgical Oncologic Patients.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Preoperative Period; Vitamin B 12 | 2018 |
Folate: a possible role in erectile dysfunction?
Topics: Adult; Case-Control Studies; Erectile Dysfunction; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Severity of Illness Index; Surveys and Questionnaires; Ultrasonography; Vitamin B 12 | 2018 |
Genetic variants of the folate metabolic system and mild hyperhomocysteinemia may affect ADHD associated behavioral problems.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alleles; Attention Deficit Disorder with Hyperactivity; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Child; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Variation; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Pilot Projects; Problem Behavior; Replication Protein C; Signal Transduction | 2018 |
Identification of vitamin B12 deficiency in vegetarian Indians.
Topics: Adult; Biomarkers; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Sample Size; Vegetarians; Vitamin B 12; Vitamin B 12 Deficiency; White People | 2018 |
[THE DIFFERENTIATED APPROACH TO PREVENTION OF NEURAL TUBE DEFECTS IN CHILDREN].
Topics: Adult; Dietary Supplements; Drinking Water; Family Characteristics; Female; Fever; Folic Acid; Gene Expression; Genetic Counseling; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Infarction; Neoplasms; Neural Tube Defects; Polymorphism, Single Nucleotide; Pregnancy; Retrospective Studies; Risk Factors; Stroke; Thrombosis; Tobacco Smoke Pollution; Ukraine; Water Pollution | 2018 |
Subacute onset leukodystrophy and visual-spatial disorders revealing phenylketonuria combined with homocysteinmia in adulthood: A case report.
Topics: Folic Acid; Humans; Hyperhomocysteinemia; Leukoencephalopathies; Male; Mutation; Phenylketonurias; Vision Disorders; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Young Adult | 2018 |
Genetic polymorphisms of key enzymes in folate metabolism affect the efficacy of folate therapy in patients with hyperhomocysteinaemia.
Topics: Aged; Cohort Studies; Female; Folic Acid; Gene Expression Regulation; Gene-Environment Interaction; Genotype; Humans; Hyperhomocysteinemia; Male; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies | 2018 |
Metabolic distress in lipid & one carbon metabolic pathway through low vitamin B-12: a population based study from North India.
Topics: Adult; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cross-Sectional Studies; Dyslipidemias; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Obesity; Triglycerides; Vitamin B 12; Vitamin B 12 Deficiency; Waist Circumference | 2018 |
Significantly higher frequencies of hemoglobin, iron, vitamin B12, and folic acid deficiencies and of hyperhomocysteinemia in patients with Behcet's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia; Behcet Syndrome; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2018 |
Association of hyperhomocysteinemia with genetic variants in key enzymes of homocysteine metabolism and methotrexate toxicity in rheumatoid arthritis patients.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Thymidylate Synthase; Tunisia; Vitamin B 12 | 2018 |
Synergistic Effect of Atorvastatin and Folic Acid on Cardiac Function and Ventricular Remodeling in Chronic Heart Failure Patients with Hyperhomocysteinemia.
Topics: Aged; Aged, 80 and over; Atorvastatin; China; Chronic Disease; Female; Folic Acid; Heart Failure; Heart Function Tests; Humans; Hyperhomocysteinemia; Male; Middle Aged; Ventricular Remodeling | 2018 |
Effect of Homocysteine on the Differentiation of CD4
Topics: Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Colon; Cyclooxygenase 2; Disease Models, Animal; Folic Acid; Group IV Phospholipases A2; Homocysteine; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Mucous Membrane; Nuclear Receptor Subfamily 1, Group F, Member 3; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Th17 Cells; Treatment Outcome; Vitamin B Complex | 2018 |
Folate-dependent constructive effect of cirrhosis on hyperhomocysteinemia.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis | 2018 |
Significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in atrophic glossitis patients.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Count; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Taiwan; Vitamin B 12; Young Adult | 2018 |
Association of vitamin B12 mediated hyperhomocysteinemia and methylenetetrafolate reductase (C677T) gene polymorphism with cognitive impairment: A population based study from North India.
Topics: Adult; Aged; Cognitive Dysfunction; Comorbidity; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Vitamin B 12 | 2018 |
A case report of branch retinal artery occlusion in a teenager due to hyperhomocysteinaemia; the interplay of genetic and nutritional defects.
Topics: Adolescent; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Malnutrition; Methylenetetrahydrofolate Reductase (NADPH2); Retinal Artery Occlusion; Vision Disorders; Visual Acuity; Visual Field Tests; Visual Fields; Vitamin B 12; Vitamin B 12 Deficiency | 2018 |
Folate/Vitamin B Alleviates Hyperhomocysteinemia-Induced Alzheimer-Like Pathologies in Rat Retina.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Dietary Supplements; Disease Models, Animal; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Rats, Sprague-Dawley; Retina; Retinal Vessels; tau Proteins; Vitamin B 12 | 2019 |
Anemia, hematinic deficiencies, and hyperhomocysteinemia in gastric parietal cell antibody-positive and -negative atrophic glossitis patients.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Count; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Taiwan; Vitamin B 12; Young Adult | 2019 |
Supplementation with dairy matrices impacts on homocysteine levels and gut microbiota composition of hyperhomocysteinemic mice.
Topics: Animals; Diet; Disease Models, Animal; Fermented Foods; Folic Acid; Gastrointestinal Microbiome; Homocysteine; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Milk | 2020 |
Relationship between Homocysteine, Folate, Vitamin B
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Hand Strength; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Lower Extremity; Male; Muscle Strength; Nutritional Status; Physical Functional Performance; Regression Analysis; Sex Factors; Vitamin B 12 | 2019 |
Association of vitamin B12 mediated hyperhomocysteinemia with depression and anxiety disorder: A cross-sectional study among Bhil indigenous population of India.
Topics: Adult; Anxiety Disorders; Cross-Sectional Studies; Depression; Female; Folic Acid; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Nutritional Physiological Phenomena; Nutritional Requirements; Polymorphism, Genetic; Population Groups; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Co-relation of Cerebral Venous Sinus Thrombosis with Vitamin B12 and Homocysteine Levels in a Tertiary Care Centre.
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Sinus Thrombosis, Intracranial; Tertiary Care Centers; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Prediction model for the efficacy of folic acid therapy on hyperhomocysteinaemia based on genetic risk score methods.
Topics: Adult; Aged; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Male; Middle Aged; Models, Biological; Polymorphism, Single Nucleotide | 2019 |
Hematinic deficiencies and hyperhomocysteinemia in gastric parietal cell antibody-positive or gastric and thyroid autoantibodies-negative atrophic glossitis patients.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Atrophy; Autoantibodies; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Taiwan; Vitamin B 12; Young Adult | 2019 |
Associations among serum folate, waist-to-hip ratio, lipid profile, and eating habits with homocysteine in an elderly Thai population.
Topics: Aged; Cross-Sectional Studies; Feeding Behavior; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Thailand; Vitamin B 12; Waist-Hip Ratio | 2019 |
Association between the BHMT gene rs3733890 polymorphism and the efficacy of oral folate therapy in patients with hyperhomocysteinemia.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alleles; Betaine-Homocysteine S-Methyltransferase; Comorbidity; Environment; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Treatment Outcome | 2019 |
Association Between Cognitive Impairment and Vitamin B12, Folate, and Homocysteine Status in Elderly Adults: A Retrospective Study.
Topics: Aged; Aged, 80 and over; Biomarkers; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Significantly higher frequencies of hematinic deficiencies and hyperhomocysteinemia in oral precancer patients.
Topics: Adult; Aged; Anemia; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Hemoglobins; Humans; Hyperhomocysteinemia; Iron; Leukoplakia, Oral; Male; Middle Aged; Mouth Diseases; Parietal Cells, Gastric; Sex Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency | 2019 |
Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in atrophic glossitis patients with or without microcytosis.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Erythropoiesis; Female; Folic Acid; Folic Acid Deficiency; Glossitis; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Iron Deficiencies; Male; Middle Aged; Parietal Cells, Gastric; Tongue; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2019 |
Does serum gastric parietal cell antibody titer have influence on anemia and vitamin B12 deficiency in atrophic glossitis patients?
Topics: Adult; Aged; Aged, 80 and over; Anemia, Macrocytic; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Tongue; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with macrocytosis.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Anemia, Macrocytic; Atrophy; Autoantibodies; Case-Control Studies; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hematinics; Hematologic Diseases; Hemoglobins; Homocysteine; Humans; Hyperhomocysteinemia; Iron; Male; Middle Aged; Parietal Cells, Gastric; Tongue; Vitamin B 12; Young Adult | 2019 |
Hyperhomocysteinemia is key for increased susceptibility to PND in aged mice.
Topics: Animals; Cognition; Dietary Supplements; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Postoperative Cognitive Complications; Postoperative Period; Preoperative Period; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2019 |
Hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with normocytosis.
Topics: Case-Control Studies; Erythrocyte Indices; Folic Acid; Folic Acid Deficiency; Glossitis; Hematinics; Hemoglobins; Humans; Hyperhomocysteinemia; Parietal Cells, Gastric; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
A novel approach in the management of hyperhomocysteinemia.
Topics: Alcohol Oxidoreductases; Animals; Choline; Cytidine Diphosphate Choline; Dietary Supplements; Endothelial Cells; Folic Acid; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Kidney; Life Style; Liver; Methionine; Models, Theoretical; Vitamin B 12; Vitamin B 6 | 2019 |
Vitamin B12 deficiency and hyperhomocysteinemia as correlates of cardiovascular risk factors in Indian subjects with coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Coronary Artery Disease; Dyslipidemias; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Congenital MTHFR deficiency causing early-onset cerebral stroke in a case homozygous for MTHFR thermolabile variant.
Topics: Asian People; Brain; Brain Diseases, Metabolic, Inborn; Cerebral Infarction; DNA; Folic Acid; Homozygote; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Stroke; Young Adult | 2013 |
MTHFR C677T polymorphism, folate, vitamin B12 and homocysteine in recurrent pregnancy losses: a case control study among North Indian women.
Topics: Abortion, Habitual; Adolescent; Adult; Amino Acid Substitution; Case-Control Studies; Female; Folic Acid; Gene Frequency; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; India; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2013 |
Homocysteine, antioxidant micronutrients and late onset dementia.
Topics: Aged; Aged, 80 and over; Antioxidants; Body Mass Index; Cognition; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Micronutrients; Nutrition Assessment; Proportional Hazards Models; Risk Factors; Socioeconomic Factors; Surveys and Questionnaires; Vitamin B 12 | 2014 |
Plasma homocysteine and folate levels and dietary folate intake in adolescents and young adults who underwent kidney transplantation during childhood.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Age Factors; Biomarkers; Cardiovascular Diseases; Child; Child Nutritional Physiological Phenomena; Cross-Sectional Studies; Diet; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Kidney; Kidney Transplantation; Linear Models; Male; Nutrition Assessment; Nutritional Status; Prevalence; Risk Factors; Time Factors; Treatment Outcome; Vitamin B Deficiency; Young Adult | 2014 |
Exercise prevents hyperhomocysteinemia in a dietary folate-restricted mouse model.
Topics: Absorption; Animals; Betaine-Homocysteine S-Methyltransferase; Diet; Disease Models, Animal; Female; Folic Acid; Homocysteine; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Physical Conditioning, Animal | 2013 |
Nutrition throughout life: folate.
Topics: Biological Availability; Cardiovascular Diseases; Drug Stability; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Neural Tube Defects; Nutrition Policy; Nutritional Physiological Phenomena; Nutritional Requirements; Nutritional Status; Pregnancy | 2012 |
Effect of multivitamins on plasma homocysteine in patients with the 5,10 methylenetetrahydrofolate reductase C677T homozygous state.
Topics: Adult; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Vitamin B 12; Vitamins | 2013 |
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and variations of homocysteine concentrations in patients with Behcet's disease.
Topics: Adult; Behcet Syndrome; Case-Control Studies; Cobamides; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Young Adult | 2013 |
[The clinical studies of hyperhomocysteinemia and Alzheimer's disease].
Topics: Alzheimer Disease; Case-Control Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 2013 |
Folic acid attenuates hyperhomocysteinemia-induced glomerular damage in rats.
Topics: Albuminuria; Animals; Cell Proliferation; Collagen; Creatinine; Folic Acid; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Kidney; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Podocytes; Random Allocation; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Up-Regulation | 2013 |
Plasma homocysteine concentrations in the acute phase after central retinal vein occlusion in a Chinese population.
Topics: Acute Disease; Aged; Asian People; Cardiovascular Diseases; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2013 |
Nutri-epigenetics ameliorates blood-brain barrier damage and neurodegeneration in hyperhomocysteinemia: role of folic acid.
Topics: Adenosylhomocysteinase; Animals; Blood-Brain Barrier; Cystathionine beta-Synthase; Diet; Epigenesis, Genetic; Folic Acid; Heterozygote; Hyperhomocysteinemia; Matrix Metalloproteinases; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Methyltransferases; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress | 2014 |
Hyperhomocysteinemia in bipolar depression: clinical and biochemical correlates.
Topics: Adult; Aged; Biomarkers; Bipolar Disorder; E-Selectin; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Middle Aged; Vitamin B 12; Young Adult | 2013 |
Plasma homocysteine, folic acid, and vitamin B₁₂ levels in patients with pseudoexfoliation syndrome, pseudoexfoliation glaucoma, and normotensive glaucoma.
Topics: Aged; Exfoliation Syndrome; Female; Folic Acid; Glaucoma; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12 | 2013 |
Smokeless tobacco use: a risk factor for hyperhomocysteinemia in a Pakistani population.
Topics: Adolescent; Adult; Cities; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Income; Male; Middle Aged; Pakistan; Pyridoxal Phosphate; Risk Factors; Tobacco, Smokeless; Vitamin B 12; Young Adult | 2013 |
Folic acid mitigates angiotensin-II-induced blood pressure and renal remodeling.
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Collagen; Drinking; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Hypertension; Kidney; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; RNA, Messenger; Tissue Inhibitor of Metalloproteinases | 2013 |
Hyperhomocysteinemia is a risk factor for Alzheimer's disease in an Algerian population.
Topics: Aged; Aged, 80 and over; Algeria; Alzheimer Disease; Case-Control Studies; Cholesterol; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Risk Factors; Thyrotropin; Uric Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2014 |
Hyperhomocysteinaemia, low folate concentrations and MTHFR C677T mutation in abdominal aortic aneurysm.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Aortography; Biomarkers; Case-Control Studies; China; Female; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Phenotype; Risk Factors; Tomography, X-Ray Computed; Vitamin B 12 | 2014 |
Plasma homocysteine concentrations in acute and convalescent changes of central retinal vein occlusion in a Chinese population.
Topics: Aged; Biomarkers; China; DNA; Electroretinography; Female; Folic Acid; Follow-Up Studies; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Microscopy, Acoustic; Middle Aged; Ophthalmoscopy; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prognosis; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Time Factors; Tomography, Optical Coherence; Vitamin B 12 | 2014 |
Hyperhomocysteinemia and assessment of its associated factors in renal transplant recipients: a single-center study in northern Iran.
Topics: Adult; Biomarkers; Blood Urea Nitrogen; Chi-Square Distribution; Creatinine; Cross-Sectional Studies; Cyclosporine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Iran; Kidney Failure, Chronic; Kidney Transplantation; Linear Models; Male; Middle Aged; Multivariate Analysis; Prevalence; Risk Factors; Time Factors; Vitamin B 12 | 2014 |
Domain specific changes in cognition at high altitude and its correlation with hyperhomocysteinemia.
Topics: Acclimatization; Adult; Altitude; Cognition; Cognitive Dysfunction; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Neuropsychological Tests; Vitamin B 12 | 2014 |
Vitamin status as a determinant of serum homocysteine concentration in type 2 diabetic retinopathy.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Prevalence; Regression Analysis; Risk Factors; Vitamin B 12; Vitamins | 2014 |
Early markers of occult megaloblastosis for low-cost detection of hyperhomocysteinemia in patients with ischaemic stroke: preventive approach for primary health care.
Topics: Anemia, Megaloblastic; Biomarkers; Brain Ischemia; Early Diagnosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neutrophils; Primary Health Care; Stroke; Vitamin B 12 | 2014 |
Correlation between low folate levels and hyperhomocysteinemia, but not with vitamin B12 in hypertensive patients.
Topics: Female; Folic Acid; Humans; Hyperhomocysteinemia; Hypertension; Male; Middle Aged; Reference Standards; Vitamin B 12 | 2014 |
Homocysteine in patients with inflammatory bowel diseases.
Topics: Adult; Aged; Colitis, Ulcerative; Crohn Disease; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Middle Aged; Prospective Studies; Young Adult | 2014 |
Nutritional status of the elderly in rural North China: a cross-sectional study.
Topics: Aged; Aged, 80 and over; Body Mass Index; China; Cholesterol; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutrition Surveys; Nutritional Status; Obesity; Prevalence; Rural Health; Rural Population; Thinness; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
The changing of serum vitamin B12 and homocysteine levels after gastrectomy in patients with gastric cancer: do they associate with clinicopathological factors?
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Gastrectomy; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2015 |
Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase.
Topics: Angiotensin II; Animals; Binding Sites; CCCTC-Binding Factor; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; DNA Methylation; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Male; Mice, Inbred C57BL; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; S-Adenosylmethionine; Sp1 Transcription Factor; Telomerase; Telomere; Telomere Shortening; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2015 |
Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism.
Topics: Animals; Apoptosis; Betaine-Homocysteine S-Methyltransferase; Catalase; Chromatography, High Pressure Liquid; Cochlea; Female; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Glutathione Synthase; Hair Cells, Auditory; Hearing Loss; Homocysteine; Hyperhomocysteinemia; In Situ Nick-End Labeling; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidation-Reduction; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase | 2015 |
Prevalence of hyperhomocysteinaemia and some of its major determinants in Shaanxi Province, China: a cross-sectional study.
Topics: Adult; Aged; Aged, 80 and over; China; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutrition Surveys; Polymorphism, Genetic; Prevalence; Risk Factors; Young Adult | 2015 |
Macrophage inflammasome mediates hyperhomocysteinemia-aggravated abdominal aortic aneurysm.
Topics: Adventitia; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Calcium Phosphates; Carrier Proteins; Caspase 1; Disease Models, Animal; Fibroblasts; Folic Acid; Gene Expression; Hyperhomocysteinemia; Inflammasomes; Interleukin-1beta; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Primary Cell Culture; Rats; Reactive Oxygen Species; RNA, Small Interfering | 2015 |
Homocysteine but not serum amyloid A, vitamin A and E related to increased risk of metabolic syndrome in post-menopausal Thai women.
Topics: Anthropometry; Body Mass Index; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Syndrome; Middle Aged; Odds Ratio; Postmenopause; Risk Factors; Serum Amyloid A Protein; Thailand; Vitamin A; Vitamin E | 2014 |
Fitting homocysteine to disease models, as well as adjusting the models to the disease.
Topics: Animals; Cardiovascular Diseases; Disease Models, Animal; Folic Acid; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidative Stress; Risk Factors; Signal Transduction; Vitamin B 12 | 2015 |
Cognitive Status According to Homocysteine and B-Group Vitamins in Elderly Adults.
Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Comorbidity; Confidence Intervals; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Odds Ratio; Prevalence; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
Association of Vitamin B12 Deficiency with Homozygosity of the TT MTHFR C677T Genotype, Hyperhomocysteinemia, and Endothelial Cell Dysfunction.
Topics: Adult; Cardiovascular Diseases; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Physical Endurance; Polymorphism, Genetic; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2015 |
Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: the role of B vitamins supplementation.
Topics: Aged; Blood Cells; Calcium; Cross-Sectional Studies; Dietary Supplements; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Telomere; Tetrahydrofolates; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D | 2016 |
Hyperhomocysteinemia predicts renal function decline: a prospective study in hypertensive adults.
Topics: Aged; Blood Pressure; Cohort Studies; Demography; Female; Folic Acid; Follow-Up Studies; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Kidney; Male; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors; Vitamin B 12 | 2015 |
Acute Myocardial Infarction in a Young Man with Hyperhomocysteinemia and Pulmonary Tuberculosis.
Topics: Acute Disease; Adult; Chest Pain; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Percutaneous Coronary Intervention; Risk Factors; Tuberculosis, Pulmonary; Vitamin B Complex | 2016 |
[Cerebral venous sinus thrombosis associated with hyperhomocysteinemia due to combined deficiencies of folate and vitamin B12].
Topics: Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Mutation; Risk Factors; Sinus Thrombosis, Intracranial; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Recalcitrant Livedoid Vasculopathy Associated with Hyperhomocysteinaemia Responding to Folic Acid and Vitamins B6/B12 Supplementation.
Topics: Adult; Female; Folic Acid; Humans; Hyperhomocysteinemia; Leg; Male; Middle Aged; Skin Diseases, Vascular; Vitamin B 12; Vitamin B 6 | 2016 |
Homocysteinemia is Associated with a Lower Degree of PBMC LINE-1 Methylation and a Higher Risk of CIN 2C in the U.S. Post-Folic Acid Fortification Era.
Topics: Adult; Body Mass Index; Contraceptives, Oral, Hormonal; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leukocytes, Mononuclear; Logistic Models; Long Interspersed Nucleotide Elements; Middle Aged; Papillomavirus Infections; Risk Factors; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Young Adult | 2016 |
Metabolic dysregulation in first-episode schizophrenia patients with respect to genetic variation in one-carbon metabolism.
Topics: Adult; Betaine-Homocysteine S-Methyltransferase; Blood Glucose; Carbon; Case-Control Studies; Dyslipidemias; Fasting; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins, HDL; Male; Metabolic Syndrome; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Minor Histocompatibility Antigens; One-Carbon Group Transferases; Polymorphism, Genetic; Prevalence; Psychotic Disorders; Schizophrenia; Triglycerides; Vitamin B 12; Young Adult | 2016 |
Comparative case-control study of homocysteine, vitamin B
Topics: Adult; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Case-Control Studies; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B 12 | 2017 |
Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats.
Topics: Aneurysm, Ruptured; Animals; Arteries; Blood Pressure; Cysteine; Cytokines; Disease Models, Animal; Female; Folic Acid; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Methionine; NADPH Oxidase 4; NADPH Oxidases; Ovariectomy; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Vitamin B Complex | 2016 |
Vitamin B12 status in women of childbearing age in the UK and its relationship with national nutrient intake guidelines: results from two National Diet and Nutrition Surveys.
Topics: Adult; Cross-Sectional Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Malnutrition; Nutrition Policy; Nutrition Surveys; Prevalence; United Kingdom; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2016 |
[Association of Crohn's disease with transcobalamin Ⅱ gene polymorphisms and serum homocysteine, folate and vitamin B12 levels in Chinese patients].
Topics: Alleles; Crohn Disease; Folic Acid; Folic Acid Deficiency; Genotype; Haplotypes; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Mutation; Polymorphism, Genetic; Prevalence; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Evaluation of Homocysteine, Vitamin B12 and Folic Acid Levels During all the Trimesters in Pregnant and Preeclamptic Womens.
Topics: Case-Control Studies; Female; Fetal Blood; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Pregnancy Trimesters; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Serum folate predicts muscle strength: a pilot cross-sectional study of the association between serum vitamin levels and muscle strength and gait measures in patients >65 years old with diabetes mellitus in a primary care setting.
Topics: Accidental Falls; Aged; Cross-Sectional Studies; Diabetes Mellitus; Female; Folic Acid; Folic Acid Deficiency; Gait; Hand Strength; Homocysteine; Humans; Hyperhomocysteinemia; Male; Muscle Strength; Pilot Projects; Primary Health Care; Risk Factors; Singapore; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D; Vitamin D Deficiency | 2016 |
Hyperhomocysteinaemia in children receiving phenytoin and carbamazepine monotherapy: a cross-sectional observational study.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child, Preschool; Cross-Sectional Studies; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Long-Term Care; Male; Phenytoin; Vitamin B Complex | 2017 |
Hyperhomocysteinemia in Greyhounds and its Association with Hypofolatemia and Other Clinicopathologic Variables.
Topics: Animals; Case-Control Studies; Dog Diseases; Dogs; Female; Folic Acid; Folic Acid Deficiency; Hyperhomocysteinemia; Male; Ohio; Pedigree; Surveys and Questionnaires; Texas; Vitamin B 12 | 2017 |
Cobalamin and folate protect mitochondrial and contractile functions in a murine model of cardiac pressure overload.
Topics: Animals; Biomarkers; Cells, Cultured; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Folic Acid; Heart Failure; Hyperhomocysteinemia; Mice; Mitochondria, Heart; Models, Biological; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Oxidative Stress; Vitamin B 12 | 2017 |
Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation.
Topics: Animals; Astrocytes; Autophagy; Cell Line, Tumor; Cell Survival; Cells, Cultured; Diet; Dietary Supplements; Endoplasmic Reticulum Stress; Folic Acid; Glucose; Humans; Hyperhomocysteinemia; Lysosomes; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Models, Biological; Oxidative Stress; Oxygen; Reperfusion Injury; Sequestosome-1 Protein; TOR Serine-Threonine Kinases; Vitamin B 12 | 2016 |
Folate Protects Hepatocytes of Hyperhomocysteinemia Mice From Apoptosis via Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Activated Endoplasmic Reticulum Stress.
Topics: Animals; Apoptosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Methylation; Endoplasmic Reticulum Stress; Folic Acid; Hepatocytes; Hyperhomocysteinemia; Mice; Mice, Knockout; Promoter Regions, Genetic | 2017 |
Association between hyperhomocysteinemia and stroke with atherosclerosis and small artery occlusion depends on homocysteine metabolism-related vitamin levels in Chinese patients with normal renal function.
Topics: Aged; Aged, 80 and over; Asian People; Case-Control Studies; Cerebrovascular Disorders; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Kidney; Male; Middle Aged; Retrospective Studies; Stroke; Vitamin B 12 | 2017 |
Folate Deficiency and Gene Polymorphisms of MTHFR, MTR and MTRR Elevate the Hyperhomocysteinemia Risk.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors | 2017 |
Pilot study of homocysteine and cysteine in patients with thrombosis in different vascular sites. Epidemiology and response to folate.
Topics: Adult; Aged; Cysteine; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pilot Projects; Thrombosis; Vitamin B 12 | 2009 |
Changes in predictors and status of homocysteine in young male adults after a dietary intervention with vegetables, fruits and bread.
Topics: Adolescent; Adult; Bread; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Norway; Riboflavin; Surveys and Questionnaires; Treatment Outcome; Vegetables; Vitamin B 12; Vitamin B Complex | 2008 |
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents | 2008 |
High plasma homocysteine is associated with the risk of coronary artery disease independent of methylenetetrahydrofolate reductase 677C-->T genotypes.
Topics: Alleles; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency | 2008 |
Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2-dependent cyclin E expression.
Topics: Adult Stem Cells; Aged; Aged, 80 and over; Animals; Cell Proliferation; Cells, Cultured; Cognition Disorders; Cyclin E; Dementia; Dentate Gyrus; Disease Models, Animal; Fibroblast Growth Factor 2; Folic Acid; Gene Expression Regulation; Homocysteine; Humans; Hyperhomocysteinemia; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurodegenerative Diseases; Neurons; Trigeminal Caudal Nucleus | 2008 |
Folate and vitamin B12 deficiencies: proceedings of a WHO technical consultation held 18-21 October, 2005, in Geneva, Switzerland. Introduction.
Topics: Anemia; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Nutritional Status; Pregnancy; Pregnancy Outcome; Public Health; Vitamin B 12; Vitamin B 12 Deficiency; World Health Organization | 2008 |
Vitamin B12 and homocysteine status in asymptomatic Indian toddlers.
Topics: Body Height; Body Weight; Child, Preschool; Comorbidity; Cross-Sectional Studies; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Prevalence; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Folate for high-risk surgical patients.
Topics: Anesthetics, Inhalation; Folic Acid; Humans; Hyperhomocysteinemia; Nitrous Oxide; Perioperative Care | 2008 |
Folate deprivation, the methionine cycle, and Alzheimer's disease.
Topics: Alzheimer Disease; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Methionine | 2008 |
Molecular mechanisms of adaptation to folate deficiency.
Topics: Animals; Antineoplastic Agents; Atherosclerosis; Carrier Proteins; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Mice; Neoplasms; Neural Tube Defects | 2008 |
Chronic hyperhomocysteinemia alters antioxidant defenses and increases DNA damage in brain and blood of rats: protective effect of folic acid.
Topics: Animals; Antioxidants; Catalase; DNA; DNA Damage; Folic Acid; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Micronucleus Tests; Parietal Lobe; Rats; Rats, Wistar | 2009 |
Is ischemic stroke risk related to folate status or other nutrients correlated with folate intake?
Topics: Adult; Aged; Aged, 80 and over; Blood Proteins; Brain Ischemia; Diet; Feeding Behavior; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Life Style; Male; Micronutrients; Middle Aged; Nutritional Requirements; Risk Factors; Sampling Studies; Surveys and Questionnaires; Taiwan | 2008 |
Letter by Greyson regarding article, "High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury".
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiotonic Agents; Coronary Occlusion; Drug Evaluation, Preclinical; Endothelium, Vascular; Folic Acid; Hyperhomocysteinemia; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Premedication; Prodrugs; Purines; Rats; Rats, Wistar | 2008 |
Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats.
Topics: Animals; Disease Models, Animal; Extracellular Matrix; Folic Acid; Homocysteine; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Glomerulus; Matrix Metalloproteinases; NADPH Oxidases; Oxidative Stress; Proto-Oncogene Proteins c-vav; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; RNA; Sclerosis; Superoxides; Tissue Inhibitor of Metalloproteinase-1; Transfection | 2009 |
[Late revelation of homocysteinuria: clinical, biological and progressive aspects].
Topics: Abnormalities, Multiple; Adult; Consanguinity; Cystathionine beta-Synthase; Epilepsies, Partial; Folic Acid; Frontal Lobe; Homocystinuria; Humans; Hyperhomocysteinemia; Lens Subluxation; Male; Thrombophlebitis; Vitamin B 6 | 2009 |
Clinical utility of genotyping the 677C>T variant of methylenetetrahydrofolate reductase in humans is decreased in the post-folic acid fortification era.
Topics: Adult; Black or African American; Female; Folic Acid; Food, Fortified; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); White People | 2009 |
Hyperhomocysteinemia is not sufficient to cause preeclampsia in an animal model: the importance of folate intake.
Topics: Animals; Disease Models, Animal; Endothelium, Vascular; Female; Folic Acid; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Pre-Eclampsia; Pregnancy | 2009 |
Relationship of homocysteine with other risk factors and outcome of ischemic stroke.
Topics: Adult; Aged; Brain Ischemia; Comorbidity; Diabetes Mellitus; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; India; Male; Middle Aged; Obesity; Risk Factors; Severity of Illness Index; Smoking; Stroke; Tomography, X-Ray Computed; Vitamin B 12 | 2009 |
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice.
Topics: Animals; Cystathionine beta-Synthase; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver; Membrane Transport Proteins; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Knockout | 2009 |
[Relationship between smoking and homocysteine concentration in ischemic stroke patients].
Topics: Aged; Brain Ischemia; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Sex Factors; Smoking; Stroke; Vitamin B 12 | 2008 |
Hyperhomocysteinemia increases beta-amyloid by enhancing expression of gamma-secretase and phosphorylation of amyloid precursor protein in rat brain.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Blotting, Western; Brain; Enzyme-Linked Immunosorbent Assay; Folic Acid; Gene Expression; Hyperhomocysteinemia; Immunohistochemistry; Immunoprecipitation; Memory Disorders; Phosphorylation; Presenilin-1; Presenilin-2; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vitamin B 12; Vitamin B Complex | 2009 |
Commentary to: "Evaluation of serum lipids and carotid artery intima media thickness in epileptic children treated with valproic acid".
Topics: Age Factors; Anticonvulsants; Carotid Stenosis; Child; Endothelial Cells; Epilepsy; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Arteriosclerosis; Lipid Metabolism Disorders; Risk Factors; Tunica Intima; Valproic Acid | 2009 |
Hyperhomocysteinaemia and poor vitamin B status in chronic obstructive pulmonary disease.
Topics: Aged; C-Reactive Protein; Case-Control Studies; Cross-Sectional Studies; Female; Folic Acid; Forced Expiratory Volume; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Logistic Models; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Risk Factors; Thrombosis; Vital Capacity; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2009 |
Treatment of hyperhomocysteinaemia in haemodialysis patients at high cardiovascular risk.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Dialysis; Risk Factors; Vascular Diseases; Vitamin B Complex | 2009 |
Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson's disease.
Topics: Analysis of Variance; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Matched-Pair Analysis; Middle Aged; Nerve Degeneration; Parkinson Disease; Reference Values; Statistics, Nonparametric; Vitamin B 12 | 2009 |
Methionine-induced hyperhomocysteinemia modulates lipoprotein profile and oxidative stress but not progression of atherosclerosis in aged apolipoprotein E knockout mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Apolipoproteins E; Aspartate Aminotransferases; Atherosclerosis; Cholesterol; Folic Acid; Glutathione; Hyperhomocysteinemia; Lipoproteins; Male; Methionine; Mice; Mice, Knockout; NF-kappa B; Oxidative Stress; RNA, Messenger | 2009 |
Multiple strokes in a newborn.
Topics: Carotid Artery, Internal; Carotid Stenosis; Cerebral Infarction; Cystathionine; Cystathionine beta-Synthase; DNA Mutational Analysis; Female; Folic Acid; Genotype; Humans; Hyperhomocysteinemia; Infant, Newborn; Magnetic Resonance Angiography; Methylenetetrahydrofolate Reductase (NADPH2); Optic Neuropathy, Ischemic; Polymorphism, Single Nucleotide; Thrombophilia | 2009 |
Exogenous folate ameliorates ethanol-induced brain hyperhomocysteinemia and exogenous ethanol reduces taurine levels in chick embryos.
Topics: Animals; Brain; Chick Embryo; Ethanol; Folic Acid; Hyperhomocysteinemia; Taurine | 2009 |
Blood levels of homocysteine, cysteine, glutathione, folic acid, and vitamin B12 in the acute phase of atherothrombotic stroke.
Topics: Acute Disease; Aged; Aged, 80 and over; Brain Ischemia; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Middle Aged; Risk Factors; Stroke; Vitamin B 12; Vitamins | 2009 |
Role of thrombotic risk factors in end-stage renal disease.
Topics: 3' Untranslated Regions; Adult; Alleles; Amino Acid Substitution; Factor V; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Point Mutation; Prothrombin; Risk Factors; Thrombophilia; Vitamin B 12; Young Adult | 2010 |
High-dose short-term folate administration modifies ambulatory blood pressure in postmenopausal women. A placebo-controlled study.
Topics: Aging; Blood Pressure; Cardiovascular Diseases; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Insulin; Middle Aged; Postmenopause; Vitamin B Complex | 2009 |
Acute homocysteine administration impairs memory consolidation on inhibitory avoidance task and decreases hippocampal brain-derived neurotrophic factor immunocontent: prevention by folic acid treatment.
Topics: Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Folic Acid; Hippocampus; Homocysteine; Hyperhomocysteinemia; Memory; Memory Disorders; Memory, Short-Term; Motor Activity; Parietal Lobe; Random Allocation; Rats; Rats, Wistar; Time Factors; Vitamin B Complex | 2009 |
Folate/homocysteine phenotypes and MTHFR 677C>T genotypes are associated with serum levels of monocyte chemoattractant protein-1.
Topics: Adult; Chemokine CCL2; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Sex Factors; Young Adult | 2009 |
A New DiaSys colorimetric assay for plasma homocysteine: application in diabetic patients.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; C-Reactive Protein; Chromatography, High Pressure Liquid; Colorimetry; Diabetes Mellitus; Female; Folic Acid; Glomerular Filtration Rate; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reproducibility of Results; Vitamin B 12 | 2009 |
[Vitamin B12 deficiency secondary to metformin therapy].
Topics: Aged; Anemia; Diabetes Mellitus, Type 2; Drug Synergism; Female; Folic Acid; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Intestinal Absorption; Male; Metformin; Middle Aged; Proton Pump Inhibitors; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Treatment of erectile dysfunction due to C677T mutation of the MTHFR gene with vitamin B6 and folic acid in patients non responders to PDE5i.
Topics: Adult; Aged; Alleles; DNA Mutational Analysis; Folic Acid; Genetic Carrier Screening; Genotype; Homozygote; Humans; Hyperhomocysteinemia; Impotence, Vasculogenic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Treatment Failure; Vitamin B 6 | 2010 |
Homocysteine and endothelial markers are increased in patients with chronic liver diseases.
Topics: Adult; Aged; Blood Coagulation Factors; Case-Control Studies; Chronic Disease; Endothelium, Vascular; Fatty Liver; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis; Male; Middle Aged; Prothrombin Time | 2009 |
[Metformin and vitamin B12 deficiency].
Topics: Aged; Anemia; Female; Folic Acid; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Intestinal Absorption; Metformin; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Hyperhomocysteinemia in epileptic patients on new antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Enzyme Induction; Epilepsy; Female; Folic Acid; Fructose; Genotype; Humans; Hyperhomocysteinemia; Lamotrigine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxcarbazepine; Phenobarbital; Polymorphism, Genetic; Topiramate; Triazines; Vitamin B 12 | 2010 |
The associations between blood levels of homocysteine, folate, vitamin B12, and retinal vascular caliber.
Topics: Aged; Aging; Arterioles; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Photography; Retinal Artery; Retinal Vein; Sex Factors; Smoking; Venules; Vitamin B 12 | 2009 |
The association between high plasma homocysteine levels and lower bone mineral density in Slovak women: the impact of vegetarian diet.
Topics: Adult; Age Distribution; Aged; Albumins; Blood Glucose; Bone Density; Calcium; Causality; Cohort Studies; Creatinine; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Phosphorus; Risk Factors; Slovakia; Vitamin B 12; Young Adult | 2010 |
Hyperhomocysteinaemia, low folate concentrations and methylene tetrahydrofolate reductase C677T mutation in acute mesenteric venous thrombosis.
Topics: Acute Disease; Adult; Aged; Asian People; Biomarkers; Case-Control Studies; Chi-Square Distribution; China; Chromatography, High Pressure Liquid; Down-Regulation; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Immunoassay; Male; Mesenteric Vascular Occlusion; Mesenteric Veins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Risk Assessment; Risk Factors; Venous Thrombosis; Vitamin B 12; Young Adult | 2010 |
Observational study on markers of cardiovascular risk in renal patient: conventional hemodialysis vs. haemofiltration online.
Topics: Biomarkers; Cardiovascular Diseases; Chi-Square Distribution; Cross-Sectional Studies; Female; Folic Acid; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Obesity; Online Systems; Renal Dialysis; Risk Assessment; Risk Factors; Treatment Outcome; Vitamin B 12 | 2009 |
Serum folate is a reliable indicator of hyperhomocysteinemia and borderline hyperhomocysteinemia in young adults.
Topics: Adolescent; Adult; Area Under Curve; Biomarkers; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Pyridoxal Phosphate; Reference Values; Risk Factors; Severity of Illness Index; Taiwan; Vitamin B 12; Young Adult | 2009 |
Hyperhomocysteinemia in patients with stasis dermatitis and ulcer: a novel finding with important therapeutic implications.
Topics: Adult; Biomarkers; Case-Control Studies; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leg Dermatoses; Male; Middle Aged; Severity of Illness Index; Treatment Outcome; Varicose Ulcer; Vitamin B Complex | 2009 |
Chronic pancreatitis is associated with hyperhomocysteinemia and derangements in transsulfuration and transmethylation pathways.
Topics: Adult; Creatinine; Cysteine; Erythrocytes; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylation; Middle Aged; Models, Biological; Multivariate Analysis; Pancreatitis, Alcoholic; Pancreatitis, Chronic; Regression Analysis; Signal Transduction; Sulfates; Sulfur; Young Adult | 2010 |
Dose-response analyses using restricted cubic spline functions in public health research.
Topics: Bone Density; Calcium, Dietary; Cardiovascular Diseases; Cholesterol, HDL; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Folic Acid; Humans; Hyperhomocysteinemia; Linear Models; Logistic Models; Nutrition Surveys; Proportional Hazards Models; Public Health; Research Design; Software | 2010 |
A case of Hughes-Stovin syndrome associated with hyperhomocysteinemia.
Topics: Anti-Inflammatory Agents; Anticoagulants; Dyspnea; Folic Acid; Hematinics; Hemoptysis; Humans; Hyperhomocysteinemia; Male; Prednisolone; Syndrome; Treatment Outcome; Warfarin; Young Adult | 2010 |
Recurrent postpartum cerebral sinus vein thrombosis as a presentation of cystathionine-beta-synthase deficiency.
Topics: Adult; Anticoagulants; Anticonvulsants; Epilepsy; Female; Folic Acid; Homocystinuria; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Pyridoxine; Recurrence; Sinus Thrombosis, Intracranial; Thrombolytic Therapy; Treatment Outcome; Vitamin B Complex; Vitamin K | 2010 |
Prevalence of hyperhomocysteinaemia in a Chinese elderly population.
Topics: Aged; Alcohol Drinking; China; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Prevalence; Sex Factors; Surveys and Questionnaires; Vitamin B 12 | 2010 |
Low cobalamin levels associated with sickle cell disease: Contrasting origins and clinical meanings in two instructive patients.
Topics: Adult; Anemia, Pernicious; Anemia, Sickle Cell; Autoantibodies; Depression; Female; Folic Acid; Gastrins; Hemoglobin SC Disease; Humans; Hydroxyurea; Hyperhomocysteinemia; Intrinsic Factor; Iron Overload; Male; Methylmalonic Acid; Pneumonia; Transcobalamins; Transfusion Reaction; Treatment Refusal; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2010 |
Higher maternal plasma folate but not vitamin B-12 concentrations during pregnancy are associated with better cognitive function scores in 9- to 10- year-old children in South India.
Topics: Adult; Brain; Child; Cognition; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; India; Male; Neurogenesis; Nutritional Status; Pregnancy; Prenatal Nutritional Physiological Phenomena; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2010 |
Hyperhomocysteinemia is not associated with reduced bone quality in humans with hip osteoarthritis.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Bone Density; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Osteoarthritis, Hip; Vitamin B 12; Vitamin B 6 | 2010 |
Major determinants of serum homocysteine concentrations in a Korean population.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Young Adult | 2010 |
NMDA receptor-mediated activation of NADPH oxidase and glomerulosclerosis in hyperhomocysteinemic rats.
Topics: Animals; Cell Line; Dizocilpine Maleate; Extracellular Matrix; Folic Acid; Gene Expression; Hyperhomocysteinemia; Kidney; Kidney Diseases; Kidney Glomerulus; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; N-Methylaspartate; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tissue Inhibitor of Metalloproteinase-1 | 2010 |
Nutrigenetic impact of daily folate intake on plasma homocysteine and folate levels in patients with different methylenetetrahydrofolate reductase genotypes.
Topics: Biomarkers; Chi-Square Distribution; Dietary Supplements; Drug Administration Schedule; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Israel; Linear Models; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Nutrigenomics; Odds Ratio; Phenotype | 2010 |
Increased levels of homocysteine in patients with ulcerative colitis.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Chi-Square Distribution; Colitis, Ulcerative; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Risk Assessment; Risk Factors; Thromboembolism; Up-Regulation; Vitamin B 12; Young Adult | 2010 |
Contribution of dietary intakes of antioxidants to homocysteine-induced low density lipoprotein (LDL) oxidation in atherosclerotic patients.
Topics: Adult; Aged; Antioxidants; Atherosclerosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Risk Factors; Vitamin B 12; Vitamin B Complex | 2010 |
Effect of lipopenic and hypotensive treatment on homocysteine levels in type 2 diabetics.
Topics: Aged; Antihypertensive Agents; Biomarkers; Case-Control Studies; Chi-Square Distribution; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Male; Middle Aged; Odds Ratio; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Triglycerides; Vitamin B 12 | 2010 |
Genetic polymorphism of methylenetetrahydrofolate reductase G1793A, hyperhomocysteinemia, and folate deficiency correlate with ulcerative colitis in central China.
Topics: Adult; Alleles; China; Colitis, Ulcerative; DNA; Female; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Prevalence; Vitamin B 12 | 2010 |
Preliminary report: hyperhomocysteinemia in patients with acute intermittent porphyria.
Topics: Adult; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Porphyria, Acute Intermittent; Pyridoxal Phosphate; Vitamin B 12 | 2010 |
Association between adherence to folic acid supplements and serum folate, and plasma homocysteine among hemodialysis patients.
Topics: Administration, Oral; Adult; Aged; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multicenter Studies as Topic; Patient Compliance; Randomized Controlled Trials as Topic; Renal Dialysis; Vitamin B 12; Vitamin B 6 | 2011 |
Association of blood lead (Pb) and plasma homocysteine: a cross sectional survey in Karachi, Pakistan.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lead; Male; Middle Aged; Pakistan; Pyridoxal Phosphate; Young Adult | 2010 |
Polymorphism of MTHFR C677T, serum vitamin levels and cognition in subjects with hyperhomocysteinemia in China.
Topics: Aged; Aged, 80 and over; Aging; Cognition; Cognition Disorders; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6; Vitamins | 2010 |
Evaluation of mild hyperhomocysteinemia during the development of atherosclerosis in apolipoprotein E-deficient and normal mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Diet; Endoplasmic Reticulum; Folic Acid; Hyperhomocysteinemia; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Time Factors | 2011 |
Could genetic analysis be useful in reducing cerebrovascular risk in hypertensive subjects with hyperhomocysteinemia and patent foramen ovale? A 2-year follow-up study.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Blood Pressure; Cerebrovascular Disorders; Chi-Square Distribution; Echocardiography, Transesophageal; Female; Folic Acid; Follow-Up Studies; Foramen Ovale, Patent; Gene Frequency; Genetic Predisposition to Disease; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Hypertension; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Polymorphism, Genetic; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial; Vitamins; Young Adult | 2010 |
Vitamin B12 and folic acid supplementation and plasma total homocysteine concentrations in pregnant Indian women with low B12 and high folate status.
Topics: Adult; Dietary Supplements; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Rural Population; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Determinants of hyperhomocysteinemia after gastric bypass surgery in obese subjects.
Topics: Adult; Creatinine; Female; Folic Acid; Gastric Bypass; Humans; Hyperhomocysteinemia; Male; Middle Aged; Obesity, Morbid; Prospective Studies; Vitamins | 2011 |
The reliability of methionine challenge test is not affected by a deficiency in pyridoxal phosphate, folic acid, or cobalamin.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Methionine; Pregnancy; Pyridoxal Phosphate; Reproducibility of Results; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2011 |
Attenuation of beta2-adrenergic receptors and homocysteine metabolic enzymes cause diabetic cardiomyopathy.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Cardiomyopathies; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Folic Acid; Glucose; Glucose Transporter Type 4; Heart Failure; Homocysteine; Hyperglycemia; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardial Contraction; Myocytes, Cardiac; Receptors, Adrenergic, beta-2; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2010 |
Congenital heart defects and biomarkers of methylation in children: a case-control study.
Topics: Biomarkers; Case-Control Studies; Child, Preschool; Down Syndrome; Female; Folic Acid; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Infant; Male; Methylation; Netherlands; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Vitamin B 12 | 2011 |
The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis.
Topics: Activated Protein C Resistance; Aged; Blood Coagulation Tests; Cohort Studies; Comorbidity; Factor V; Female; Folic Acid; Homocysteine; Homocystinuria; Hospital Mortality; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Point Mutation; Protein C; Psychotic Disorders; Respiration, Artificial; Sepsis; Shock, Septic; Thrombophilia; Vitamin B 12 | 2010 |
Prevention: B vitamins and CVD--failure to find a simple solution.
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Vitamin B Complex | 2010 |
Effects of folic acid plus vitamin B12 vs placebo in myocardial infarction survivors.
Topics: Colorectal Neoplasms; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Myocardial Infarction; Neoplasms; North America; Risk; Vitamin B 12; Vitamin B Complex | 2010 |
[The relationship of methylenetetrahydrofolate reductase G1793A gene polymorphism, hyperhomocysteinaemia and ulcerative colitis].
Topics: Adult; Case-Control Studies; Colitis, Ulcerative; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Vitamin B 12 | 2010 |
Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney.
Topics: Acetophenones; Animals; Cells, Cultured; Folic Acid; Humans; Hyperhomocysteinemia; Kidney; Male; Methionine; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 2011 |
Homocysteine, folic acid and vitamin B12 levels in maternal and umbilical cord plasma and homocysteine levels in placenta in pregnant women with pre-eclampsia.
Topics: Adult; Case-Control Studies; Female; Fetal Blood; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Placenta; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Vitamin B 12 | 2011 |
Homocysteine induces oxidative-nitrative stress in heart of rats: prevention by folic acid.
Topics: Animals; Antioxidants; Catalase; Disease Models, Animal; Female; Fluoresceins; Folic Acid; Heart Diseases; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Male; Myocardium; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Reactive Nitrogen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2011 |
Atherosclerotic and thrombophilic risk factors in patients with ischemic central retinal vein occlusion.
Topics: Acute Disease; Aged; Atherosclerosis; Biomarkers; Dyslipidemias; Factor VIII; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Ischemia; Male; Retinal Vein Occlusion; Risk Factors; Thrombophilia | 2011 |
A derangement of the maternal lipid profile is associated with an elevated risk of congenital heart disease in the offspring.
Topics: Adult; Apolipoproteins B; Body Mass Index; Case-Control Studies; Child; Cholesterol, LDL; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Hyperglycemia; Hyperhomocysteinemia; Logistic Models; Multivariate Analysis; Odds Ratio; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Young Adult | 2012 |
Hyperhomocysteinemia decreases bone blood flow.
Topics: Animals; Biomarkers; Biomechanical Phenomena; Blood Pressure; Bone Density; Bone Remodeling; Disease Models, Animal; Folic Acid; Homocysteine; Hyperhomocysteinemia; Laser-Doppler Flowmetry; Male; Osteoporosis; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tibia; Time Factors; Up-Regulation; Vitamin B 12 | 2011 |
Folate and vitamin B12 improved alcohol-induced hyperhomocysteinemia in rats.
Topics: Animals; Cytochromes; Folic Acid; Homocysteine; Hyperhomocysteinemia; Liver; Liver Cirrhosis, Alcoholic; Liver Function Tests; Male; Matrix Metalloproteinase 2; Rats; Rats, Wistar; Vitamin B 12; Vitamin B Complex | 2011 |
Hyperhomocysteinaemia, vascular related pregnancy complications and the response to vitamin supplementation in pregnant women of Pakistan.
Topics: Abruptio Placentae; Case-Control Studies; Cohort Studies; Eclampsia; Female; Folic Acid; Gestational Age; Homocysteine; Hospitals, Teaching; Humans; Hyperhomocysteinemia; Pakistan; Pregnancy; Pregnancy Outcome; Vitamin B 6; Vitamin B Complex | 2010 |
Folic acid enlarges the armamentarium for the treatment of coronary vasospasm.
Topics: Acetylcholine; Animals; Coronary Vasospasm; Coronary Vessels; Female; Folic Acid; Hyperhomocysteinemia; Male; Vasoconstriction | 2013 |
What is the meaning of homocysteine in patients on dialysis?
Topics: Adult; Aged; Biomarkers; Brazil; C-Reactive Protein; Creatine Kinase; Creatinine; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-6; Kidney Failure, Chronic; Linear Models; Lipids; Male; Malnutrition; Middle Aged; Peritoneal Dialysis; Prevalence; Renal Dialysis; Risk Factors; Tumor Necrosis Factor-alpha; Vitamin B 12 | 2011 |
Prevalence and risk factors of hyperhomocysteinemia in Tunisian patients with Crohn's disease.
Topics: Adolescent; Adult; Age Factors; Aged; Body Mass Index; C-Reactive Protein; Case-Control Studies; Creatinine; Crohn Disease; Female; Folic Acid; Humans; Hyperhomocysteinemia; Logistic Models; Male; Middle Aged; Prevalence; Risk Factors; Smoking; Tunisia; Vitamin B 12; Young Adult | 2011 |
Homocysteine mediated decrease in bone blood flow and remodeling: role of folic acid.
Topics: Animals; Bone Density; Bone Remodeling; Folic Acid; Homocysteine; Hyperhomocysteinemia; Matrix Metalloproteinase 9; Mice; Nitric Oxide; Osteoporosis; Oxidative Stress; Regional Blood Flow; Tibia; Tibial Arteries | 2011 |
Vitamin B12 deficiency, hyperhomocysteinemia and thrombosis: a case and control study.
Topics: Adult; Aged; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Vitamin B12 and folate deficiency and elevated plasma total homocysteine in workers with chronic exposure to chromate.
Topics: Adult; China; Chromates; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2011 |
Folate is related to phosphorylated neurofilament-H and P-tau (Ser396) in rat brain.
Topics: Animals; Brain; Female; Folic Acid; Frontal Lobe; Homocysteine; Homocystine; Hyperhomocysteinemia; Methionine; Methylation; Neurofilament Proteins; Phosphoproteins; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Wistar; tau Proteins | 2011 |
The basis of differential responses to folic acid supplementation.
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Genetic; Nutrigenomics; Polymorphism, Single Nucleotide; Twins, Dizygotic; Twins, Monozygotic; Vitamin B 12 | 2011 |
Carotid dissection causing stroke in a 13-year-old boy with mild hyperhomocysteinemia: case report.
Topics: Adolescent; Anticoagulants; Brain; Carotid Artery, Internal; Carotid Artery, Internal, Dissection; Folic Acid; Humans; Hyperhomocysteinemia; Male; Stroke; Ultrasonography; Vitamin B 12 | 2011 |
TT genotype of the methylenetetrahydrofolate reductase C677T polymorphism is an important determinant for homocysteine levels in multi-ethnic Malaysian ischaemic stroke patients.
Topics: China; Ethnicity; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Malaysia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Genetic; Stroke; Vitamin B 12 | 2011 |
Vitamin B12, folate and hyperhomocysteinemia in patients with epilepsy.
Topics: Epilepsy; Folic Acid; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2011 |
Folic acid improves acetylcholine-induced vasoconstriction of coronary vessels isolated from hyperhomocysteinemic mice: an implication to coronary vasospasm.
Topics: Acetylcholine; Animals; Cholinergic Agonists; Coronary Vasospasm; Coronary Vessels; Drug Synergism; Female; Folic Acid; Hyperhomocysteinemia; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Vasoconstriction; Vitamin B Complex | 2011 |
Novel inborn error of folate metabolism: identification by exome capture and sequencing of mutations in the MTHFD1 gene in a single proband.
Topics: Amino Acid Metabolism, Inborn Errors; Anemia, Megaloblastic; Exome; Female; Folic Acid; Humans; Hyperhomocysteinemia; Infant; Metabolism, Inborn Errors; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Mutation; Severe Combined Immunodeficiency | 2011 |
Chronic hyperhomocysteinemia causes vascular remodelling by instigating vein phenotype in artery.
Topics: Animals; Aorta; Blotting, Western; Chronic Disease; Collagen; Cystathionine beta-Synthase; Elastin; Ephrin-B2; Folic Acid; Gene Expression; Genotype; Hemorheology; Hyperhomocysteinemia; Male; Matrix Metalloproteinases; Mice; Mice, Transgenic; Phenotype; Receptor, EphB4; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases; Tunica Intima; Veins | 2011 |
Folate/vitamin-B12 prevents chronic hyperhomocysteinemia-induced tau hyperphosphorylation and memory deficits in aged rats.
Topics: Aging; Animals; Chronic Disease; Dietary Supplements; Disease Models, Animal; Drug Therapy, Combination; Folic Acid; Hyperhomocysteinemia; Male; Memory Disorders; Phosphorylation; Rats; Rats, Sprague-Dawley; tau Proteins; Vitamin B 12 | 2011 |
Folic acid alleviates oxidative stress and hyperhomocysteinemia involved in testicular dysfunction of hypothyroid rats.
Topics: Animals; Antioxidants; Folic Acid; Glutathione; Hyperhomocysteinemia; Hypothyroidism; Male; Malondialdehyde; Oxidative Stress; Rats; Testicular Diseases; Testis | 2011 |
Association of MTHFR and RFC1 gene polymorphism with hyperhomocysteinemia and its modulation by vitamin B12 and folic acid in an Indian population.
Topics: Adult; Alleles; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Polymorphism, Single Nucleotide; Prevalence; Replication Protein C; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 2012 |
Reference interval and determinants of the serum homocysteine level in a Korean population.
Topics: Adult; Aged; Analysis of Variance; Asian People; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Life Style; Male; Middle Aged; Nutritional Status; Reference Values; Republic of Korea; Statistics, Nonparametric | 2011 |
Hyperhomocysteinemia and related genetic polymorphisms correlate with ulcerative colitis in Chinese Han population in Central China [corrected].
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Alleles; Amino Acid Substitution; Asian People; China; Colitis, Ulcerative; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2012 |
Serum homocysteine and folate but not vitamin B12 are predictors of CHD mortality in older adults.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Coronary Disease; Down-Regulation; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; New South Wales; Prognosis; Proportional Hazards Models; Risk Assessment; Risk Factors; Up-Regulation; Vitamin B 12 | 2012 |
[Serum levels of antioxidants and vitamins related to the homocystein's metabolism during postmenopause].
Topics: Abdominal Fat; Antioxidants; Body Mass Index; Cross-Sectional Studies; Estrogens; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Hormone Replacement Therapy; Humans; Hyperhomocysteinemia; Middle Aged; Motor Activity; Overweight; Postmenopause; Progesterone; Risk; Urban Population; Vitamin B 12; Vitamin B 6; Waist-Hip Ratio | 2005 |
Hypothesis: hyperhomocysteinemia is an indicator of oxidant stress.
Topics: Biomarkers; Cardiovascular Diseases; Endothelium; Folic Acid; Hyperhomocysteinemia; Models, Biological; Molecular Structure; Oxidative Stress | 2011 |
[Hyperhomocysteinemia and schizophrenia: case control study].
Topics: Adult; Case-Control Studies; Chronic Disease; Comorbidity; Cross-Sectional Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Reference Values; Schizophrenia; Schizophrenic Psychology; Statistics as Topic; Vitamin B 12 | 2011 |
Status of B-vitamins and homocysteine in diabetic retinopathy: association with vitamin-B12 deficiency and hyperhomocysteinemia.
Topics: Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Diabetic Retinopathy; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prognosis; Risk Factors; Vitamin B 12 Deficiency; Vitamin B Complex | 2011 |
Fortification of flours with folic acid reduces homocysteine levels in Brazilian women.
Topics: Adult; Biomarkers; Brazil; Cardiovascular Diseases; Cross-Sectional Studies; Diet; Dietary Fiber; Edible Grain; Female; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Nutrition Assessment; Nutrition Policy; Obesity; Triticum; Zea mays | 2011 |
Hyperhomocysteinemia in Tunisian bipolar I patients.
Topics: Adult; Bipolar Disorder; Case-Control Studies; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Middle Aged; Odds Ratio; Polymorphism, Genetic; Tunisia; Vitamin B 12 | 2011 |
Serum holotranscobalamine, vitamin B12, folic acid and homocysteine levels in patients with vitiligo.
Topics: Adult; Biomarkers; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Logistic Models; Male; Middle Aged; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitiligo; Young Adult | 2012 |
Hyperhomocysteinemia among Omani autistic children: a case-control study.
Topics: Autistic Disorder; Biomarkers; Case-Control Studies; Child, Preschool; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Reference Values; Vitamin B 12 | 2011 |
Folic acid improves inner ear vascularization in hyperhomocysteinemic mice.
Topics: Adult; Animals; Auditory Threshold; Cochlea; Collagen Type IV; Cystathionine beta-Synthase; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Folic Acid; Hearing Loss; Heterozygote; Humans; Hyperhomocysteinemia; Male; Matrix Metalloproteinase 9; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Oxidative Stress; RNA, Messenger | 2012 |
Therapy of hyperhomocysteinemia in hemodialysis patients: effects of folates and N-acetylcysteine.
Topics: Acetylcysteine; Aged; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 2012 |
The effects of ethanol upon hydric balance and arterial pressure in rats: folic acid as a possible hypotensor.
Topics: Alcohol Drinking; Alcohol-Induced Disorders; Aldosterone; Animals; Antihypertensive Agents; Creatinine; Dietary Supplements; Ethanol; Folic Acid; Hyperhomocysteinemia; Hypertension; Kidney; Male; Potassium; Rats; Rats, Wistar; Sodium; Water-Electrolyte Balance | 2012 |
Folate depletion changes gene expression of fatty acid metabolism, DNA synthesis, and circadian cycle in male mice.
Topics: Animals; Circadian Rhythm; Darkness; DNA; DNA Methylation; DNA Replication; Fatty Acids; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Hyperhomocysteinemia; Light; Lipid Metabolism; Liver; Male; Melatonin; Mice; Nuclear Proteins; Phosphatidate Phosphatase; Vitamin B Complex | 2012 |
Coenzyme Q10, hyperhomocysteinemia and MTHFR C677T polymorphism in levodopa-treated Parkinson's disease patients.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; Ubiquinone; Vitamin B 12 | 2012 |
Pregnancy and a rare MTHFR haplotype.
Topics: Adult; Female; Folic Acid; Haplotypes; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications | 2012 |
Marked gender difference in plasma total homocysteine concentrations in indian adults with low vitamin B₁₂.
Topics: Adult; Age Factors; Body Composition; Erythrocytes; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2011 |
Role of folic acid depletion on homocysteine serum level in children and adolescents with epilepsy and different MTHFR C677T genotypes.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Vitamin B 12 | 2012 |
Nɛ-homocysteinyl-lysine isopeptide is associated with progression of peripheral artery disease in patients treated with folic acid.
Topics: Aged; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolism; Middle Aged; Oxidative Stress; Peptides; Peripheral Arterial Disease; Proteins; Vitamin B Complex | 2012 |
Polymorphisms in MTHFR, MS and CBS genes and homocysteine levels in a Pakistani population.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Pakistan; Polymorphism, Single Nucleotide; Pyridoxal Phosphate; Risk Factors; Sex Factors; Vitamin B 12; Young Adult | 2012 |
Serum folate, total homocysteine levels and methylenetetrahydrofolate reductase 677C>T polymorphism in young healthy female Japanese.
Topics: Adolescent; Amplified Fragment Length Polymorphism Analysis; Child; Diet; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Health Surveys; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2012 |
Salutary effect of NFκB inhibitor and folacin in hyperhomocysteinemia-hyperlipidemia induced vascular dementia.
Topics: Acetylcholinesterase; Animals; Dementia, Vascular; Ditiocarb; Endothelium, Vascular; Folic Acid; Hyperhomocysteinemia; Hyperlipidemias; Male; Maze Learning; Methionine; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar | 2012 |
Increased homocysteinemia is associated with beneficial effects on body weight after long-term high-protein, low-fat diet in rats.
Topics: Adipose Tissue; Animals; Diet, Fat-Restricted; Dietary Proteins; Energy Intake; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Obesity; Rats; Rats, Long-Evans; Weight Gain | 2012 |
Folate and vitamin B12 deficiency and hyperhomocysteinemia promote oxidative stress in adult type 2 diabetes.
Topics: Adult; Antioxidants; Case-Control Studies; Diabetes Mellitus, Type 2; Diet; Female; Folic Acid; Folic Acid Deficiency; Glutathione; Hospitals, University; Humans; Hyperhomocysteinemia; Male; Middle Aged; Oman; Outpatient Clinics, Hospital; Oxidative Stress; Oxidoreductases; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2012 |
[Folic acid prevents Bcl-2 hypomethylation in rats with hyperhomocysteinemia].
Topics: Animals; Aorta, Thoracic; DNA Methylation; Folic Acid; Hyperhomocysteinemia; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; RNA, Messenger | 2012 |
Homocysteine and cardiovascular risk: the perils of reductionism in a complex system.
Topics: Animals; Coronary Disease; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk; Vitamin B Complex | 2012 |
Comment on Folic acid improves inner ear vascularization in hyperhomocysteinemic mice, Hearing Research 2012, 284: 42-51 (Kundu, Munjal, N. Tyagi, Sen, A. Tyagi, S. Tyagi).
Topics: Animals; Ear, Inner; Folic Acid; Humans; Hyperhomocysteinemia; Male | 2012 |
Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia.
Topics: Animals; Apoptosis Regulatory Proteins; Blotting, Western; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Chromatography, Gel; Cytoskeletal Proteins; Diet; Folic Acid; Homocysteine; Hyperhomocysteinemia; Inflammasomes; Interleukin-1beta; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Electron, Transmission; NLR Family, Pyrin Domain-Containing 3 Protein; Podocytes; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sclerosis; Vascular Endothelial Growth Factor A | 2012 |
Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians.
Topics: Adult; Cholesterol; Coronary Artery Disease; Female; Folic Acid; Genetic Association Studies; Homocysteine; Humans; Hyperhomocysteinemia; India; Lipoproteins, HDL; Lipoproteins, LDL; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Smoking; Triglycerides; Vitamin B 12 | 2012 |
Homocysteine, the kidney, and vascular disease.
Topics: Cardiovascular Diseases; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Diseases; Male | 2012 |
Plasma phospholipid polyunsaturated fatty acids and homocysteine in Chinese type 2 diabetes patients.
Topics: Adult; Aged; Algorithms; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Outpatient Clinics, Hospital; Phospholipids; Prevalence; Vitamin B 12 | 2012 |
Oxidative stress and platelet activation in subjects with moderate hyperhomocysteinaemia due to MTHFR 677 C→T polymorphism.
Topics: Biomarkers; Cardiovascular Diseases; Comorbidity; Cross-Sectional Studies; Diabetes Mellitus; Dinoprost; Dyslipidemias; Folic Acid; Homocystinuria; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Oxidative Stress; Platelet Activation; Polymorphism, Single Nucleotide; Psychotic Disorders; Smoking; Thromboxane B2 | 2012 |
Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline Deficiency; Dietary Supplements; Enzyme Inhibitors; Folic Acid; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Wistar; Sarcosine | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults.
Topics: Adult; Aged; Betaine-Homocysteine S-Methyltransferase; Cholesterol Ester Transfer Proteins; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Predictive Value of Tests; Reference Values; Retinol-Binding Proteins, Cellular; Risk Factors; Scavenger Receptors, Class B; Serine C-Palmitoyltransferase; Sex Distribution | 2012 |
Higher plasma homocysteine is associated with lower vitamin B6 status in critically ill surgical patients.
Topics: Aged; Critical Illness; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intensive Care Units; Male; Middle Aged; Nutritional Status; Postoperative Complications; Prevalence; Pyridoxal Phosphate; Vitamin B 12; Vitamin B 6 Deficiency; Vitamin B Complex | 2012 |
[Abnormal findings during newborn period of 160 patients with early-onset methylmalonic aciduria].
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Child; Child, Preschool; China; Female; Folic Acid; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylmalonic Acid; Neonatal Screening; Retrospective Studies; Vitamin B 12 | 2012 |
Elevated plasma homocysteine level is not primarily related to Alzheimer's disease.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Effect of dietary supplementation with folate on choline deficiency-induced hyperhomocysteinemia in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Choline Deficiency; Cystathionine beta-Synthase; Dietary Supplements; Folic Acid; Hyperhomocysteinemia; Liver; Male; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Serine; Tetrahydrofolates | 2012 |
Homocysteinemia in mice with genetic betaine homocysteine S-methyltransferase deficiency is independent of dietary folate intake.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Body Weight; Cysteine; Diet; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Mice; Mice, Knockout; Organ Size | 2012 |
Relationship of cognitive function with B vitamin status, homocysteine, and tissue factor pathway inhibitor in cognitively impaired elderly: a cross-sectional survey.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Mental Status Schedule; Neuropsychological Tests; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Folic acid fortification ameliorates hyperhomocysteinemia caused by a vitamin B₆-deficient diet supplemented with L-methionine.
Topics: Animals; Body Weight; Dietary Supplements; Eating; Folic Acid; Hyperhomocysteinemia; Male; Methionine; Pilot Projects; Rats; Rats, Wistar; Vitamin B 6 Deficiency | 2012 |
Conversion from mild cognitive impairment to dementia: influence of folic acid and vitamin B12 use in the VITA cohort.
Topics: Aged; Aging; Atrophy; Austria; Brain; Cognitive Dysfunction; Cohort Studies; Dementia; Dietary Supplements; Disease Progression; Female; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Prospective Studies; Retrospective Studies; Vitamin B 12 | 2012 |
Plasma homocysteine and vitamin B12 serum levels, red blood cell folate concentrations, C677T methylenetetrahydrofolate reductase gene mutation and risk of recurrent miscarriage: a case-control study in Spain.
Topics: Abortion, Spontaneous; Adult; Case-Control Studies; Erythrocytes; Female; Folic Acid; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Odds Ratio; Polymorphism, Single Nucleotide; Spain; Vitamin B 12 | 2013 |
Plasma homocysteine levels in dry eye patients.
Topics: Dry Eye Syndromes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Luminescent Measurements; Male; Middle Aged; Prospective Studies; Surveys and Questionnaires; Vitamin B 12 | 2013 |
Homocysteine, folate, vitamin B-12, and physical function in older adults: cross-sectional findings from the Singapore Longitudinal Ageing Study.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Gait; Geriatric Assessment; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Middle Aged; Mobility Limitation; Postural Balance; Prospective Studies; Singapore; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Acute myocardial infarction in a young patient with hyperhomocysteinaemia.
Topics: Acute Disease; Adult; Betaine; Coronary Vessels; Folic Acid; Heart; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Myocardium; Thrombosis; Troponin; Ventricular Function, Left | 2012 |
Palm tocotrienol-rich fraction reduced plasma homocysteine and heart oxidative stress in rats fed with a high-methionine diet.
Topics: Administration, Oral; Animals; Catalase; Cycas; Diet; Dietary Supplements; Folic Acid; Glutathione Peroxidase; Heart; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tocotrienols | 2013 |
The effects of normalizing hyperhomocysteinemia on clinical and operative outcomes in patients with critical limb ischemia.
Topics: Aged; Aged, 80 and over; Amputation, Surgical; Biomarkers; Chi-Square Distribution; Critical Illness; Disease-Free Survival; Drug Therapy, Combination; Endovascular Procedures; Female; Folic Acid; Hemodynamics; Homocysteine; Humans; Hyperhomocysteinemia; Ischemia; Kaplan-Meier Estimate; Limb Salvage; Logistic Models; Lower Extremity; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Risk Factors; Time Factors; Treatment Outcome; Vascular Patency; Vitamin B 12; Vitamin B Complex | 2012 |
[Correlation between plasma concentrations of homocysteine and diabetic polyneuropathy evaluated with the Semmes-Weinstein monofilament test in patients with type 2 diabetes mellitus].
Topics: Age Factors; Aged; Alcohol Drinking; Cardiovascular Diseases; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Progression; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypesthesia; Hypoglycemic Agents; Hypolipidemic Agents; Male; Middle Aged; Overweight; Physical Examination; Risk Factors; Severity of Illness Index; Smoking; Vitamin B 12 | 2013 |
Induction of hyperhomocysteinemia models vascular dementia by induction of cerebral microhemorrhages and neuroinflammation.
Topics: Animals; Brain; Cerebral Hemorrhage; Dementia, Vascular; Diet; Disease Models, Animal; Folic Acid; Humans; Hyperhomocysteinemia; Inflammation; Interleukin-1beta; Interleukin-6; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Memory Disorders; Methionine; Mice; Mice, Inbred C57BL; Vitamin B 12; Vitamin B 6 | 2013 |
Homocysteine plasma levels in patients treated with antiepileptic drugs depend on folate and vitamin B12 serum levels, but not on genetic variants of homocysteine metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anticonvulsants; Cystathionine beta-Synthase; Epilepsy; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Tetrahydrofolate Dehydrogenase; Transcobalamins; Vitamin B 12 | 2013 |
Folate deficiency is associated with oxidative stress, increased blood pressure, and insulin resistance in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Folic Acid; Folic Acid Deficiency; Glucose Intolerance; Hyperhomocysteinemia; Hypertension; Insulin Resistance; Male; Metabolic Syndrome; Oxidative Stress; Rats; Rats, Inbred SHR | 2013 |
Association between hypocobalaminaemia and hyperhomocysteinaemia in dogs.
Topics: Animals; Breeding; Dog Diseases; Dogs; Female; Folic Acid; Gastrointestinal Diseases; Homocysteine; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 12 Deficiency | 2013 |
Hyperhomocysteinemia and cobalamin deficiency in young Asian Indians in the United States.
Topics: Adult; Diet, Vegetarian; Female; Folic Acid; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Hyperhomocysteinemia; India; Malabsorption Syndromes; Male; Sex Factors; United States; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Folate supplementation after heart transplantation: effects on homocysteine plasma levels and allograft vascular disease.
Topics: Coronary Angiography; Creatinine; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Time Factors; Transplantation, Homologous; Vascular Diseases | 2002 |
Methylenetetrahydrofolate reductase: a link between folate and riboflavin?
Topics: Folic Acid; Genotype; Hematinics; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Oxidoreductases Acting on CH-NH Group Donors; Riboflavin | 2002 |
Hyperhomocysteinemia in children on renal replacement therapy.
Topics: Adolescent; Adult; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Humans; Hyperhomocysteinemia; Infant; Kidney Failure, Chronic; Kidney Transplantation; Male; Renal Dialysis; Risk Factors; Vitamin B 12 | 2002 |
Plasma homocysteine concentration changes after renal transplantation in children.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Male; Serum Albumin; Vitamin B 12 | 2002 |
[Frequency of hyperhomocysteinemia in hemodialysis patients with folic acid supplementation].
Topics: Adult; Age Factors; Aged; Female; Folic Acid; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Dialysis; Time Factors; Vitamin B 12 | 2002 |
Hyperhomocysteinemia in rheumatoid arthritis: influence of methotrexate treatment and folic acid supplementation.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Disability Evaluation; Drug Therapy, Combination; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Health Status; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methotrexate; Middle Aged; Surveys and Questionnaires; Treatment Outcome | 2002 |
Homocysteine and "Buerger's disease".
Topics: Adult; Diagnosis, Differential; Drug Therapy, Combination; Female; Folic Acid; Humans; Hyperhomocysteinemia; Thromboangiitis Obliterans; Vitamin B 12 | 2002 |
Methylenetetrahydrofolate reductase gene mutation and hyperhomocysteinemia as a risk factor for coronary heart disease in the Indian population.
Topics: Adult; Coronary Disease; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Vitamin B 12 | 2002 |
Clinical trials testing the homocysteine hypothesis.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Clinical Trials as Topic; Edible Grain; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2002 |
Hyperhomocysteinemia in children with renal transplants.
Topics: Adolescent; Blood Glucose; Child; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Regression Analysis; Vitamin B 12 | 2002 |
Folic acid and vitamin B(12) supplementation attenuates isoprenaline-induced myocardial infarction in experimental hyperhomocysteinemic rats.
Topics: Animals; Blood Pressure; Creatine Kinase; Folic Acid; Glutathione; Heart Rate; Hemodynamics; Hyperhomocysteinemia; Isoproterenol; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Methionine; Myocardial Infarction; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Vitamin B 12 | 2002 |
The effect of vitamin B6 and folate supplements on plasma homocysteine and serum lipids levels in patients on regular hemodialysis.
Topics: Adult; Aged; Body Mass Index; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipids; Male; Middle Aged; Renal Dialysis; Risk Factors; Vitamin B 6 | 2001 |
Renal tubulointerstitial injury in weanling rats with hyperhomocysteinemia.
Topics: Age Factors; Animal Feed; Animals; Choline; Folic Acid; Homocysteine; Hyperhomocysteinemia; Methionine; Nephritis, Interstitial; Rats; Rats, Inbred F344; Weaning | 2002 |
Role of impaired renal function as a cause of elevated plasma homocysteine concentration in psychogeriatric patients.
Topics: Age Factors; Aged; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Male; Mental Disorders; Predictive Value of Tests; Vitamin B 12 | 2002 |
Homocysteine, folate and vitamin B12 as risk factors for acute myocardial infarction in a Southeast Asian population.
Topics: Adult; Aged; Asian People; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Logistic Models; Male; Middle Aged; Myocardial Infarction; Risk Factors; Seroepidemiologic Studies; Singapore; Vitamin B 12 | 2002 |
Severe methylenetetrahydrofolate reductase deficiency revealed by a pulmonary embolism in a young adult.
Topics: Adult; Contraceptives, Oral, Hormonal; DNA Mutational Analysis; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Mutation; Mutation, Missense; Pedigree; Phenotype; Pulmonary Embolism | 2002 |
Serum folate and homocysteine levels in head and neck squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Disease Progression; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Hyperhomocysteinemia; Neopterin; Prognosis; Risk Factors | 2002 |
Hyperhomocysteinemia due to short-term folate deprivation is related to electron microscopic changes in the rat brain.
Topics: Animals; Basement Membrane; Brain; Capillaries; Cell Nucleus; Cerebral Cortex; Cytoplasm; Endothelium, Vascular; Folic Acid; Folic Acid Deficiency; Hyperhomocysteinemia; Male; Microcirculation; Microscopy, Electron; Mitochondria; Rats; Rats, Sprague-Dawley | 2002 |
[Vascular risk factors].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Arteriosclerosis; Cardiovascular Diseases; Chlamydia Infections; Controlled Clinical Trials as Topic; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Folic Acid; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Hypertension; Hypolipidemic Agents; Infections; Male; Middle Aged; Multicenter Studies as Topic; Obesity; Randomized Controlled Trials as Topic; Risk Factors; Vitamin B 12; Vitamin B Complex | 2002 |
Hyperhomocysteinaemia and risk of thrombosis in systemic lupus erythematosus patients.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kuwait; Lupus Erythematosus, Systemic; Male; Risk Factors; Thrombosis | 2002 |
Association between serum aspartate transaminase and homocysteine levels in hemodialysis patients.
Topics: Aspartate Aminotransferases; Female; Folic Acid; Forecasting; Hepatitis B Antibodies; Hepatitis B Antigens; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Renal Dialysis; Uremia; Vitamin B Complex | 2002 |
Moderate hyperhomocysteinaemia and immune activation in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Neopterin; Parkinson Disease; Vitamin B 12 | 2002 |
Plasma total homocysteine, folate, and vitamin B12 status in Korean adults.
Topics: Adult; Age Factors; Aged; Area Under Curve; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Korea; Male; Middle Aged; Nutritional Status; Prevalence; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Hyperhomocysteinemia and vitamin B-12 deficiency in elderly using Title IIIc nutrition services.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Dietary Services; Female; Folic Acid; Georgia; Geriatrics; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Nutritional Support; Prevalence; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
The effect of folic acid, vitamin B6 and vitamin B12 on the homocysteine levels in rabbits fed by methionine-enriched diets.
Topics: Animals; Diet; Dose-Response Relationship, Drug; Drug Combinations; Female; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Methionine; Rabbits; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2002 |
Hyperhomocysteinemia is related to a decreased blood level of vitamin B12 in the second and third trimester of normal pregnancy.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intrinsic Factor; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Receptors, Peptide; Statistics as Topic; Vitamin B 12 | 2002 |
[Hyperhomocysteinemia, coagulation disorders, inflammations: new risk factors for stroke].
Topics: Adult; Blood Coagulation Disorders; C-Reactive Protein; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Meta-Analysis as Topic; Middle Aged; Primary Prevention; Prognosis; Pyridoxine; Risk Factors; Sinus Thrombosis, Intracranial; Stroke; Time Factors; Vitamin B 12 | 2002 |
Elevated plasma homocysteine levels in patients treated with levodopa: association with vascular disease.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Risk Factors; Vitamin B 12 | 2003 |
Vitamin B-12 metabolism in HIV-infected patients in the age of highly active antiretroviral therapy: role of homocysteine in assessing vitamin B-12 status.
Topics: Adult; Antiretroviral Therapy, Highly Active; Diagnosis, Differential; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutrition Assessment; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Hyperhomocysteinaemia: time to screen and treat?
Topics: Animals; Antioxidants; Child; Evidence-Based Medicine; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; New Zealand; Randomized Controlled Trials as Topic; Risk Factors; Survival Rate; Vitamins | 2002 |
Folate status and a new repletion cut-off value in a group of healthy Majorcan women.
Topics: Adolescent; Adult; Aged; Female; Fluorescence Polarization Immunoassay; Folic Acid; Gene Frequency; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Radioimmunoassay; Reference Values; Spain | 2003 |
Latent coeliac disease, hyperhomocysteinemia and pulmonary thromboembolism: a close link?
Topics: Celiac Disease; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pulmonary Embolism; Thromboembolism; Venous Thrombosis | 2003 |
Medical hypothesis: hyperhomocysteinemia is a risk factor for estrogen-induced hormonal cancer.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Estradiol; Estrogens; Estrogens, Catechol; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kinetics; Methylation; Models, Biological; Mutagenicity Tests; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Risk Factors; S-Adenosylhomocysteine; Uterine Neoplasms; Vitamin B 12; Vitamin B 6 | 2003 |
Serum homocysteine level in Behçet's disease.
Topics: Adult; Behcet Syndrome; Case-Control Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Vitamin B 12 | 2002 |
Plasma homocysteine levels correlated to interactions between folate status and methylene tetrahydrofolate reductase gene mutation in women with unexplained recurrent pregnancy loss.
Topics: Abortion, Habitual; Adolescent; Adult; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy | 2003 |
Hyperhomocysteinemia in Asian Indians living in the United States.
Topics: Adult; Area Under Curve; Blood Glucose; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Insulin; Male; Middle Aged; United States; Vitamin B 12; White People | 2003 |
Familial hyperhomocysteinemia: multiple venous thrombosis in four generations of a family.
Topics: Adult; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nitroprusside; Pedigree; Venous Thrombosis; Vitamin B 12; Warfarin | 2003 |
Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nutritional Status; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12 | 2003 |
Homocysteine, folate, vitamin B12 levels, and C677T MTHFR mutation in children with renal failure.
Topics: Adolescent; Child; Child, Preschool; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Point Mutation; Predictive Value of Tests; Prevalence; Regression Analysis; Vitamin B 12 | 2003 |
Folate deficiency is a common finding in psychogeriatric patients.
Topics: Aged; Aged, 80 and over; Aging; Cognition Disorders; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Regression Analysis; Vitamin B 12 | 2002 |
Prevalence and mechanisms of hyperhomocysteinemia in elderly hospitalized patients.
Topics: Aged; Aged, 80 and over; Aging; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutritional Status; Prevalence; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
The 677 C-T methylenetetrahydrofolate reductase mutation does not predict increased maternal homocysteine during pregnancy.
Topics: Adult; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Retrospective Studies | 2003 |
[Hyperhomocysteinemia hastens myocardial infarct and stroke. Prevention.with leaf salads and vitamins].
Topics: Adult; Age Factors; Aged; Arteriosclerosis; Clinical Trials as Topic; Dementia; Diet; Drug Therapy, Combination; Female; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Prospective Studies; Risk Factors; Sex Factors; Stroke; Vegetables; Vitamin B 12; Vitamin B 6 | 2003 |
Genetic evidence that nitric oxide modulates homocysteine: the NOS3 894TT genotype is a risk factor for hyperhomocystenemia.
Topics: Adult; Amino Acid Substitution; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Northern Ireland; Point Mutation; Prospective Studies; Risk Factors; Vitamin B 12 | 2003 |
Plasma total homocysteine in uncomplicated pregnancy and in preeclampsia.
Topics: Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Vitamin B 12 | 2003 |
Determinants and distributions of plasma total homocysteine concentrations among school children in Taiwan.
Topics: Adolescent; Age Factors; Anthropometry; Cardiovascular Diseases; Child; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Schools; Sex Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Hyperhomocysteinemia in cerebral vein thrombosis.
Topics: Adolescent; Adult; Case-Control Studies; Child; Female; Folic Acid; Homocystine; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Thrombophilia; Venous Thrombosis; Vitamin B 12 | 2003 |
Hyperhomocysteinemia and vitamin score: correlations with silent brain ischemic lesions and brain atrophy.
Topics: Aged; Aged, 80 and over; Atrophy; Brain; Brain Ischemia; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B 12; Vitamin B 6; Vitamins | 2003 |
Determinants of hyperhomocysteinemia in patients with chronic liver disease and after orthotopic liver transplantation.
Topics: Adult; Area Under Curve; Case-Control Studies; Chronic Disease; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases; Liver Transplantation; Male; Metabolic Clearance Rate; Methionine; Middle Aged; Vitamin B 12; Vitamin B 6 | 2003 |
Homocysteine levels in polymyalgia rheumatica and giant cell arteritis: influence of corticosteroid therapy.
Topics: Aged; Brain Ischemia; Drug Therapy, Combination; Female; Folic Acid; Giant Cell Arteritis; Glucocorticoids; Homocystine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Polymyalgia Rheumatica; Vitamin B 12 | 2003 |
Relations between molecular and biological abnormalities in 11 families from siblings affected with methylenetetrahydrofolate reductase deficiency.
Topics: Child; Female; Folic Acid; Genes, Recessive; Homocysteine; Humans; Hyperhomocysteinemia; Male; Metabolism, Inborn Errors; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; RNA Splice Sites | 2003 |
Vitamin B12 and folate status of older New Zealand women.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; New Zealand; Nutritional Status; Prevalence; Vitamin B 12 | 2003 |
Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and the B-vitamins: a facet of nature-nurture interplay.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Vitamin B 12; Vitamin B 6 | 2003 |
Hyperhomocysteinaemia and vascular disease--a role for DNA hypomethylation?
Topics: Animals; Comorbidity; DNA Methylation; Embolism, Cholesterol; Folic Acid; Gene Expression; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Leukocytes; Rabbits; Risk Factors | 2003 |
Expression of matrix metalloproteinase-9 in mononuclear cells of hyperhomocysteinaemic subjects.
Topics: Female; Folic Acid; Humans; Hyperhomocysteinemia; Leukocytes, Mononuclear; Male; Matrix Metalloproteinase 9; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2003 |
Vitamin B-12 status, particularly holotranscobalamin II and methylmalonic acid concentrations, and hyperhomocysteinemia in vegetarians.
Topics: Adult; Aged; Biomarkers; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylmalonic Acid; Middle Aged; Osmolar Concentration; Transcobalamins; Vitamin B 12 | 2003 |
Obesity and hyperhomocysteinaemia after kidney transplantation.
Topics: Adult; Aged; Cohort Studies; Combined Modality Therapy; Diet Therapy; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Obesity; Postoperative Complications; Pravastatin; Probability; Prospective Studies; Risk Assessment; Treatment Outcome; Vitamin B 6 | 2003 |
Vitamin B12-B6-folate treatment improves blood-brain barrier function in patients with hyperhomocysteinaemia and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Blood-Brain Barrier; Cognition Disorders; Drug Therapy, Combination; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Serum Albumin; Vitamin B 12; Vitamin B 6 | 2003 |
Three B's, or not three B's? Do folic acid, vitamin B6, and vitamin B12 protect against heart disease? That is the question.
Topics: Folic Acid; Heart Diseases; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B 6 | 2003 |
Adverse effect of nitrous oxide in a child with 5,10-methylenetetrahydrofolate reductase deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Anesthetics, Inhalation; Cells, Cultured; DNA Mutational Analysis; Fatal Outcome; Fibroblasts; Folic Acid; Genes, Recessive; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Infant; Male; Metabolism, Inborn Errors; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Nitrous Oxide; Oxidoreductases; Point Mutation; Polymorphism, Genetic; RNA | 2003 |
Study on the relationship between plasma homocysteine and acute cerebral vascular disease.
Topics: Cerebral Hemorrhage; Cerebral Infarction; Chromatography, High Pressure Liquid; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2000 |
[Acral purpura and hyperhomocysteinemia].
Topics: Aged; Biopsy; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Male; Nails; Purpura; Recurrence | 2003 |
Variations in the lipid profile of patients with chronic renal failure, treated with folic acid.
Topics: Arteriosclerosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Erythrocytes; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intravenous; Kidney Failure, Chronic; Lipids; Male; Middle Aged; Renal Dialysis; Triglycerides | 2003 |
Notes on 'Effects of folic acid treatment on homocysteine levels and vascular disease in hemodialysis patients' by Righetti M et al.
Topics: Folic Acid; Humans; Hyperhomocysteinemia; Renal Dialysis; Vascular Diseases; Vitamin B 12 | 2003 |
Association between hyperhomocysteinemia and primary pulmonary hypertension.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Creatinine; Fasting; Female; Folic Acid; Humans; Hyperhomocysteinemia; Hypertension, Pulmonary; Logistic Models; Male; Middle Aged; Vitamin B 12 | 2003 |
Homocysteine plasma levels after suspension of vitamin treatment.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Clinical Protocols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Vitamin B 12 | 2003 |
Treatment of hyperhomocysteinemia in pediatric heart transplant recipients.
Topics: Adolescent; Antioxidants; Biomarkers; Child; Child Welfare; Child, Preschool; Combined Modality Therapy; Creatinine; Female; Folic Acid; Follow-Up Studies; Heart Transplantation; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant Welfare; Male; Statistics as Topic; Treatment Outcome; Vitamin A; Vitamin B 12; Vitamin E | 2003 |
Does hyperhomocysteinemia increase the risk of thrombosis in Behçet's disease?
Topics: Adult; Analysis of Variance; Behcet Syndrome; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Prevalence; Reference Values; Risk Factors; Thrombosis; Vitamin B 12 | 2003 |
Methionine synthase (MTR) 2756 (A --> G) polymorphism, double heterozygosity methionine synthase 2756 AG/methionine synthase reductase (MTRR) 66 AG, and elevated homocysteinemia are three risk factors for having a child with Down syndrome.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alleles; Case-Control Studies; Child; Down Syndrome; Female; Ferredoxin-NADP Reductase; Flavoproteins; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Sicily | 2003 |
Clinical B12 deficiency in one case of recurrent spontaneous pregnancy loss.
Topics: Abortion, Habitual; Adult; Female; Folic Acid; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Vitamin B 12 Deficiency | 2003 |
Hyperhomocysteinemia in patients with heart failure referred for cardiac transplantation: preliminary observations.
Topics: Biomarkers; Cardiomyopathies; Coronary Artery Disease; Creatinine; Female; Florida; Folic Acid; Heart Failure; Heart Transplantation; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Oxygen Consumption; Pulmonary Wedge Pressure; Retrospective Studies; Severity of Illness Index; Statistics as Topic; Stroke Volume; Treatment Outcome | 2003 |
The incidence of hyperhomocysteinaemia in vascular patients.
Topics: Aged; Aortic Aneurysm, Abdominal; Chronic Disease; Female; Folic Acid; Humans; Hyperhomocysteinemia; Intermittent Claudication; Ischemia; Leg; Lipids; Male; Middle Aged; Vascular Diseases; Vitamin B 12 | 2003 |
The C677T mutation in methylenetetrahydrofolate reductase gene, plasma homocysteine concentration and the risk of coronary artery disease.
Topics: Adult; Aged; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Factors; Threonine; Vitamin B 12 | 2003 |
Lowering plasma homocysteine.
Topics: Arteriosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12 | 2003 |
Hyperhomocystinemia in children with inflammatory bowel disease.
Topics: Adolescent; Aging; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Tetrahydrofolates; Thromboembolism; Vitamin B 12; von Willebrand Factor | 2003 |
Hyperhomocysteinemic subjects have enhanced expression of lectin-like oxidized LDL receptor-1 in mononuclear cells.
Topics: Adult; Aged; Female; Folic Acid; Gene Expression Regulation; Humans; Hyperhomocysteinemia; Leukocytes, Mononuclear; Male; Middle Aged; Receptors, LDL; Receptors, Oxidized LDL; RNA, Messenger; Scavenger Receptors, Class E; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2003 |
[Plasma homocysteine in human immunodeficiency virus infected patient].
Topics: Adult; Anti-HIV Agents; Arteriosclerosis; Biomarkers; Case-Control Studies; Female; Folic Acid; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Male; P-Selectin; Risk Factors; Smoking; Vitamin B 12 | 2003 |
[Serum homocysteine in children and adolescents. Relation with family history of cardiovascular disease].
Topics: Adolescent; Cardiovascular Diseases; Child; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Lipoproteins; Male; Risk Factors; Vitamin B 12 | 2003 |
Hyperhomocysteinemia and B-vitamin status after discontinuation of oral anticoagulation therapy in patients with a history of venous thromboembolism.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Retrospective Studies; Substance Withdrawal Syndrome; Thromboembolism; Vitamin B 12; Warfarin | 2003 |
Can mild-to-moderate hyperhomocysteinaemia impair endothelial function in the absence of other risk factors for cardiovascular disease?
Topics: Arteriosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Risk Factors | 2004 |
Pregnancy outcome in patients with a history of recurrent spontaneous miscarriages and documented thrombophilias.
Topics: Abortion, Habitual; Adult; Antibodies, Antiphospholipid; Aspirin; Female; Folic Acid; Heparin, Low-Molecular-Weight; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Thrombophilia; Vitamin B 12; Vitamin B 6 | 2004 |
Evidence suggests diabetes outcomes linked to homocysteine.
Topics: Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B Complex | 2003 |
Effects of dietary folic acid supplementation on cerebrovascular endothelial dysfunction in rats with induced hyperhomocysteinemia.
Topics: Animals; Blotting, Western; Brain; Cerebrovascular Circulation; Dietary Supplements; Endothelium, Vascular; Excitatory Amino Acid Transporter 2; Folic Acid; Hematinics; Homocystine; Hyperhomocysteinemia; Immunohistochemistry; Male; Nitric Oxide Synthase; Rats; Vascular Cell Adhesion Molecule-1 | 2004 |
[Hyperhomocysteinemia and deep-vein thrombosis].
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Restriction Fragment Length; Venous Thrombosis; Vitamin B 12 | 2003 |
Plasma homocysteine concentrations in adolescents with subclinical hypothyroidism.
Topics: Adolescent; Cholesterol; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypothyroidism; Isoantibodies; Kidney; Kidney Function Tests; Thyroiditis, Autoimmune; Thyrotropin; Thyroxine; Triiodothyronine; Vitamin B 12 | 2003 |
Folate, homocysteine levels, methylenetetrahydrofolate reductase (MTHFR) 677C --> T variant, and the risk of myocardial infarction in young women: effect of female hormones on homocysteine levels.
Topics: Adolescent; Adult; Case-Control Studies; Contraceptives, Oral; Female; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Infarction; Risk Factors; Vitamin B 12 | 2004 |
Hyperhomocysteinemia and oxidative stress in hemodialysis: effects of supplementation with folic acid.
Topics: Ascorbic Acid; Dietary Supplements; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipid Peroxidation; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Proteins; Renal Dialysis; Vitamin B 12; Vitamin E | 2003 |
Plasma homocysteine after insulin infusion in type II diabetic patients with and without methionine intolerance.
Topics: Blood Glucose; Cysteine; Diabetes Mellitus, Type 2; DNA; Female; Folic Acid; Glucose Clamp Technique; Homocysteine; Humans; Hyperhomocysteinemia; Insulin; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymerase Chain Reaction; Vitamin B 12; Vitamin B 6 | 2004 |
[Migraine, inflammation, genes. New risk factors for stroke].
Topics: Adult; Arteriosclerosis; Aspirin; C-Reactive Protein; Case-Control Studies; Contraceptives, Oral; Female; Fibrinogen; Folic Acid; Humans; Hyperhomocysteinemia; Inflammation; Male; Meta-Analysis as Topic; Migraine Disorders; Risk Factors; Smoking; Stroke; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator; Vitamin B 12; Vitamin B 6 | 2003 |
Hyperhomocysteinaemia & folic acid supplementation in patients with high risk of coronary artery disease.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Coronary Artery Disease; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunoassay; Male; Microscopy, Fluorescence; Middle Aged; Risk Factors; Time Factors; Vitamin B 12 | 2004 |
Serum total homocysteine levels, folate, and B-vitamins intake and coronary heart disease risk factors among tri-ethnic college students.
Topics: Adult; Black or African American; Coronary Disease; Female; Florida; Folic Acid; Hispanic or Latino; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Risk Factors; Sex Factors; Smoking; Universities; Vitamin B 12; Vitamin B 6; White People | 2004 |
Eat right and exercise for lower homocysteine levels and less chance of heart disease.
Topics: Adult; Age Factors; Coronary Disease; Exercise; Feeding Behavior; Female; Florida; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Smoking; Vitamin B 12; Vitamin B 6 | 2004 |
Mild hyperhomocysteinemia induced by feeding rats diets rich in methionine or deficient in folate promotes early atherosclerotic inflammatory processes.
Topics: Animals; Aorta; Arteriosclerosis; Chemokine CCL2; Diet; Endothelium, Vascular; Folic Acid; Folic Acid Deficiency; Hyperhomocysteinemia; Inflammation; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Methionine; NF-kappa B; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine | 2004 |
Heterozygous methylene tetrahydrofolate reductase mutation with mild hyperhomocysteinemia associated with deep vein thrombosis.
Topics: Adult; Arterial Occlusive Diseases; Erythrocytes; Folic Acid; Heterozygote; Humans; Hyperhomocysteinemia; Iliac Vein; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Popliteal Vein; Vena Cava, Inferior; Venous Thrombosis; Vitamin B 12 | 2004 |
Hyperhomocysteinemia in patients with Behçet's disease: is it due to inflammation or therapy?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; C-Reactive Protein; Colchicine; Drug Therapy, Combination; Eye Diseases; Female; Folic Acid; Glucocorticoids; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Male; Thrombosis; Vitamin B 12 | 2005 |
Parenteral vitamin B12 therapy of hyperhomocysteinemia in end-stage renal disease.
Topics: Administration, Oral; Aged; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylmalonic Acid; Middle Aged; Parenteral Nutrition; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
[Myocardial infarction as an initial symptom of antiphospholipid syndrome, factor V Leiden mutation, and hyperhomocysteinemia].
Topics: Activated Protein C Resistance; Adult; Antiphospholipid Syndrome; Factor V; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; Point Mutation; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
Homocysteine and folic acid are inversely related in black women with preeclampsia.
Topics: Adolescent; Adult; Arteriosclerosis; Black People; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Maternal Age; Pennsylvania; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; White People | 2004 |
[Comparative study of the detection of plasma folate with microbial assay and radioimmunoassay].
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Male; Middle Aged; Radioimmunoassay | 2004 |
Vitamin vs. a possible risk factor. Folate may offer protection--but don't let your guard down.
Topics: Adult; Cardiovascular Diseases; Child; Folic Acid; Humans; Hyperhomocysteinemia | 2004 |
Mild hyperhomocysteinemia in adult patients with sickle cell disease: a common finding unrelated to folate and cobalamin status.
Topics: Adult; Aged; Anemia, Sickle Cell; Creatinine; Female; Folic Acid; Hemoglobin SC Disease; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Reproducibility of Results; Vitamin B 12 | 2004 |
Fibrate treatment and prevalence risk of mild hyperhomocysteinaemia in clinical coronary heart disease patients.
Topics: Case-Control Studies; Coronary Disease; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Hypolipidemic Agents; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prevalence; Retrospective Studies; Vitamin B 12 | 2004 |
Plasma homocysteine levels and risk of Alzheimer disease.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Comorbidity; Confounding Factors, Epidemiologic; Cross-Sectional Studies; Cysteine; Dementia; Diabetes Mellitus; Ethnicity; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Memory; Neuropsychological Tests; New York City; Prevalence; Risk Factors; Sampling Studies; Stroke; Vitamin B 12; Vitamin B 6 | 2004 |
Hyperhomocysteinemia, low folate and vitamin B12 concentrations, and methylene tetrahydrofolate reductase mutation in cerebral venous thrombosis.
Topics: Adolescent; Adult; Case-Control Studies; Female; Folic Acid; Humans; Hyperhomocysteinemia; Incidence; Intracranial Thrombosis; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Nutritional Status; Risk Factors; Socioeconomic Factors; Vitamin B 12 | 2004 |
Homocysteine in Alzheimer disease and vascular dementia.
Topics: Aged; Aged, 80 and over; Albumins; Alzheimer Disease; Chromatography, High Pressure Liquid; Dementia, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Risk Factors; Severity of Illness Index; Vitamin B 12 | 2004 |
Common polymorphisms in methylenetetrahydrofolate reductase (MTHFR): relationships with plasma homocysteine concentrations and cognitive status in elderly northern italian subjects.
Topics: Aged; Aged, 80 and over; Catchment Area, Health; Cognition Disorders; Female; Folic Acid; Gene Expression; Humans; Hyperhomocysteinemia; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neuropsychological Tests; Point Mutation; Polymorphism, Genetic; Prevalence; Risk Factors; Severity of Illness Index | 2004 |
Homocysteine and cognitive performance in healthy elderly subjects.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Dementia, Vascular; Female; Folic Acid; Health Status; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Nutritional Status; Phonetics; Psychometrics; Severity of Illness Index; Vitamin B 12; Vitamin B 6; Vocabulary | 2004 |
Prevention of cardiovascular events after percutaneous coronary intervention.
Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Coronary Restenosis; Drug Therapy, Combination; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Platelet Aggregation Inhibitors; Risk Factors; Stents; Vitamin B 12; Vitamin B 6 | 2004 |
Polymorphisms in the methylenetetrahydrofolate reductase and methionine synthase reductase genes and homocysteine levels in Brazilian children.
Topics: Brazil; Child; Child, Preschool; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors; Vitamin B 12 | 2004 |
Hyperhomocysteinemia in healthy young men and elderly men with normal serum folate concentration is not associated with poor vascular reactivity or oxidative stress.
Topics: Adult; Aged; Aging; Antioxidants; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Male; Oxidative Stress; Vasodilation | 2004 |
Is folic acid the answer?
Topics: Cardiovascular Diseases; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors | 2004 |
Hyperhomocysteinemia in patients with Cushing's syndrome.
Topics: Adult; Aged; Case-Control Studies; Circadian Rhythm; Cushing Syndrome; Cysteine; DNA; Female; Folic Acid; Homocysteine; Humans; Hydrocortisone; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Osmolar Concentration; Polymorphism, Genetic; Threonine | 2004 |
MTHFR C677T polymorphism, folic acid and hyperhomocysteinemia in levodopa treated patients with Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cytosine; Female; Folic Acid; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Tetrahydrofolates; Thymine | 2004 |
Folate and cobalamin synergistically decrease the risk of high plasma homocysteine in a nonsupplemented elderly institutionalized population.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Diet; Drug Synergism; Female; Folic Acid; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Risk Factors; Vitamin B 12; Vitamin B Complex | 2004 |
Folate therapy and in-stent restenosis.
Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Coronary Restenosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stents; Vitamin B 6; Vitamin B Complex | 2004 |
Serum vitamin B12 and folic Acid levels in acute cerebral atherothrombotic infarction.
Topics: Acute Disease; Aged; Female; Folic Acid; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Male; Middle Aged; Reference Values; Risk Factors; Vitamin B 12 | 2004 |
Modest increase in plasma homocysteine follows levodopa initiation in Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Folic Acid; Humans; Hyperhomocysteinemia; Levodopa; Middle Aged; Parkinson Disease; Prospective Studies; Vitamin B 12 | 2004 |
Vitamins after angioplasty: maybe not such a good idea after all.
Topics: Angioplasty, Balloon, Coronary; Contraindications; Coronary Restenosis; Folic Acid; Humans; Hyperhomocysteinemia; Stents; Vitamin B 12; Vitamin B 6 | 2004 |
Changes of homocysteine levels and arterial endothelial function in patients with high risk of coronary artery disease after 6-month folic acid supplementation.
Topics: Aged; Arteries; Chromatography, High Pressure Liquid; Coronary Artery Disease; Dietary Supplements; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Time; Treatment Outcome; Vitamin B 12 | 2004 |
Alteration of homocysteine catabolism in pre-eclampsia, HELLP syndrome and placental insufficiency.
Topics: Cystathionine; Cystatin C; Cystatins; Female; Folic Acid; HELLP Syndrome; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Methylmalonic Acid; Oxidative Stress; Placental Insufficiency; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Uric Acid; Vitamin B 12; Vitamin B 6 | 2004 |
The risk of folate and vitamin B(12) deficiencies associated with hyperhomocysteinemia among pregnant women.
Topics: Adolescent; Adult; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Korea; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2004 |
Intravenous treatment of hyperhomocysteinemia in patients on chronic hemodialysis--a pilot study.
Topics: Aged; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Infusions, Intravenous; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Pilot Projects; Probability; Prospective Studies; Pyridoxine; Risk Assessment; Severity of Illness Index; Treatment Outcome; Vitamin B 12 | 2004 |
Effect of folic acid on methionine and homocysteine metabolism in end-stage renal disease.
Topics: Administration, Oral; Adult; Aged; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kinetics; Male; Methionine; Methylation; Middle Aged; Renal Dialysis | 2005 |
Folate deficiency increases postischemic brain injury.
Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Colorimetry; DNA Damage; Folic Acid; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Infarction, Middle Cerebral Artery; Mice; Mice, Transgenic; Oxygen; Reperfusion; Reperfusion Injury; Risk; Stroke; Time Factors; Uracil-DNA Glycosidase | 2005 |
Influence of serum folic acid levels on plasma homocysteine concentrations in patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Methotrexate; Middle Aged; Statistics, Nonparametric; Vitamin B 12; Vitamin B Complex | 2006 |
Beneficial effects of Bifidobacteria in a gastroresistant seamless capsule on hyperhomocysteinemia in hemodialysis patients.
Topics: Bifidobacterium; Capsules; Colony Count, Microbial; Escherichia coli; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Indican; Intestines; Probiotics; Renal Dialysis; Uremia | 2005 |
Homocysteine and its nutritional determinants in two ethnic groups of Slovakia.
Topics: Adult; Biomarkers; Case-Control Studies; Feeding Behavior; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Middle Aged; Nutrition Surveys; Slovakia; Vitamin B 12; Vitamin B 6 | 2004 |
Distribution of 5,10-methylenetetrahydrofolate reductase (C667T) polymorphism and its association with red blood cell 5-methyltetrahydrofolate in the healthy Iranians.
Topics: Analysis of Variance; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Requirements; Polymorphism, Genetic; Tetrahydrofolates; Vitamin B 12 | 2005 |
Stroke and recurrent pregnancy loss due to hyperhomocysteinaemia.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Abortion, Habitual; Brain; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Infarction, Middle Cerebral Artery; Middle Aged; Mutation; Platelet Aggregation Inhibitors; Pregnancy; Stroke; Treatment Outcome; Vitamin B 12 | 2005 |
Folic acid supplementation can reduce the endothelial damage in rat brain microvasculature due to hyperhomocysteinemia.
Topics: Animals; Cerebrovascular Circulation; Dietary Supplements; Disease Models, Animal; Endothelium, Vascular; Energy Intake; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Reference Values; Thiobarbituric Acid Reactive Substances; Vitamin B 12; Weight Gain | 2005 |
Folic acid reverses hyper-responsiveness of LPS-induced chemokine secretion from monocytes in patients with hyperhomocysteinemia.
Topics: Arteriosclerosis; Case-Control Studies; Cell Culture Techniques; Chemokines; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Inflammation; Lipopolysaccharides; Monocytes; NADPH Oxidases | 2005 |
Plasma vitamin B12, folate and homocysteine levels in gastrectomized men.
Topics: Case-Control Studies; Folic Acid; Gastrectomy; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Male; Middle Aged; Peptic Ulcer; Risk Factors; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Bad actor in cardiovascular disease may play role in fractures.
Topics: Cardiovascular Diseases; Female; Folic Acid; Fractures, Bone; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B 6 | 2005 |
Hyperhomocysteinemia in L-dopa treated Parkinson's disease patients: effect of cobalamin and folate administration.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Parkinson Disease; Vitamin B 12 | 2005 |
[A clinical study of hyperhomocysteinemia in rheumatological diseases].
Topics: Adolescent; Adult; Child; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Rheumatic Diseases; Vitamin B 12 | 2005 |
[Homocysteine and low dietary intake: two complementary forms of impairment (correction of improvement)].
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Thromboembolism; Vitamin B 12; Vitamin B 6 | 2005 |
Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment.
Topics: Adult; Anticoagulants; Betaine; Cognition Disorders; Confusion; Disease Progression; Drug Therapy, Combination; Folic Acid; Frontal Lobe; Homocysteine; Humans; Hyperhomocysteinemia; Leukoaraiosis; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Remission Induction; Seizures; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2005 |
Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample.
Topics: Aged; Antioxidants; Australia; Brain; Case-Control Studies; Causality; Creatinine; Cross-Sectional Studies; Depressive Disorder; Depressive Disorder, Major; Female; Folic Acid; Folic Acid Deficiency; Health Status Indicators; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Personality Assessment; Predictive Value of Tests; Psychometrics; Reference Values; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Polymorphisms of genes involved in homocysteine metabolism in preeclampsia and in uncomplicated pregnancies.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Case-Control Studies; Cystathionine beta-Synthase; Female; Ferredoxin-NADP Reductase; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Vitamin B 12 | 2005 |
Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction.
Topics: Adult; Aged; Aging; Body Mass Index; Case-Control Studies; Female; Fluorescence Polarization Immunoassay; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Infarction; Obesity; Pakistan; Pyridoxal Phosphate; Smoking; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2005 |
Reduced plasma homocysteine levels in levodopa/entacapone treated Parkinson patients.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cross-Sectional Studies; Drug Therapy, Combination; Enzyme Inhibitors; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Vitamin B 12 | 2005 |
Evaluation of markers of endothelial damage in cases of young myocardial infarction.
Topics: Adult; Age of Onset; Biomarkers; Case-Control Studies; E-Selectin; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Male; Myocardial Infarction; P-Selectin; Platelet Endothelial Cell Adhesion Molecule-1 | 2005 |
[The relationship between carotid artery atherosclerosis and hyperhomocysteinaemia].
Topics: Adult; Aged; Aged, 80 and over; Carotid Artery Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Middle Aged; Risk Factors; Vitamin B 12 | 2005 |
Folate and cobalamin deficiencies and hyperhomocysteinemia in Bangladesh.
Topics: Adult; Aged; Areca; Bangladesh; Cohort Studies; Creatinine; Diagnosis, Differential; Diet, Vegetarian; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Prospective Studies; Sex Factors; Smoking; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
[Folic acid in hyperhomocysteinemia?].
Topics: Contraindications; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Long-Term Care; Risk Factors; Spinal Diseases; Treatment Outcome; Vitamin B 12; Vitamin B 12 Deficiency | 2005 |
Prevalence of hyperhomocysteinaemia, activated protein C resistance and prothrombin gene mutation in inflammatory bowel disease.
Topics: Activated Protein C Resistance; Adult; Colitis, Ulcerative; Crohn Disease; Factor V; Factor VIII; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Middle Aged; Mutation; Protein C; Prothrombin; Vitamin B 12 | 2005 |
Prevalence of hyperhomocysteinemia in adult gluten-sensitive enteropathy at diagnosis: role of B12, folate, and genetics.
Topics: Adult; Biomarkers; Celiac Disease; Chromatography, High Pressure Liquid; DNA; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Prevalence; Prospective Studies; Radioimmunoassay; Risk Factors; Vitamin B 12 | 2005 |
Prevalence and mechanisms of hyperhomocysteinemia in chronic alcoholics.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcoholism; Avitaminosis; Comorbidity; Cystathionine beta-Synthase; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methionine; Methylation; Middle Aged; Prevalence | 2005 |
[Plasma homocysteine concentration and its relationship with the development of preeclampsia. Effect of prenatal administration of folic acid].
Topics: Adolescent; Adult; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Poverty; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimesters; Socioeconomic Factors | 2005 |
Folate deficiency-induced hyperhomocysteinemia attenuates, and folic acid supplementation restores, the functional activities of rat coagulation factors XII, X, and II.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Factor X; Factor XII; Folic Acid; Folic Acid Deficiency; Hyperhomocysteinemia; Male; Prothrombin; Rats; Rats, Inbred WKY | 2005 |
Hyperhomocysteinaemia induced by dietary folate restriction causes kidney oxidative stress in rats.
Topics: Animals; Antioxidants; Chemokine CCL2; Folic Acid; Free Radical Scavengers; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Kidney; Lipid Peroxidation; Male; Oxidative Stress; Proteins; Rats; Rats, Wistar; Receptors, LDL; Superoxide Dismutase; Vitamin B Deficiency; Weight Loss | 2005 |
Hyperhomocysteinemia and cognitive function: more than just a casual link?
Topics: Aging; Cognition; Cognition Disorders; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors | 2005 |
Plasma homocysteine levels in patients with isolated coronary artery ectasia.
Topics: Biomarkers; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Dilatation, Pathologic; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Vitamin B 12 | 2005 |
Association of B vitamins status and homocysteine levels in elderly Taiwanese.
Topics: Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutrition Surveys; Nutritional Status; Sex Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 2005 |
Co-administration of N-acetylcysteine, vitamin B12 and folate in cognitively impaired hyperhomocysteinaemic patients.
Topics: Acetylcysteine; Administration, Oral; Aged; Aged, 80 and over; Antioxidants; Dietary Supplements; Drug Therapy, Combination; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Memory Disorders; Memory, Short-Term; Treatment Outcome; Vitamin B 12 | 2005 |
Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans.
Topics: Adult; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Diet, Vegetarian; Female; Folic Acid; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Triglycerides; Vegetables; Vitamin B 12 | 2005 |
[Folate reduces monocyte chemoattractant protein-1 expression in rats with hyperhomocysteinemia].
Topics: Animals; Aorta; Chemokine CCL2; Endothelium, Vascular; Folic Acid; Homocysteine; Hyperhomocysteinemia; Leukocytes, Mononuclear; Male; Methionine; Random Allocation; Rats; Rats, Sprague-Dawley | 2005 |
Folic acid reduces adhesion molecules VCAM-1 expession in aortic of rats with hyperhomocysteinemia.
Topics: Animals; Aorta; Folic Acid; Hyperhomocysteinemia; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vascular Cell Adhesion Molecule-1 | 2006 |
Vitamin B12 deficiency is the dominant nutritional cause of hyperhomocysteinemia in a folic acid-fortified population.
Topics: Aged; Aged, 80 and over; California; Folic Acid; Humans; Hyperhomocysteinemia; Middle Aged; Nutritional Status; Prevalence; Risk Factors; Vitamin B 12 Deficiency | 2005 |
Young hemodialysis patients are exposed to hyperhomocysteinemia.
Topics: Adult; Alcohol Drinking; Cardiovascular Diseases; Cross-Sectional Studies; Electrocardiography; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Ischemia; Prognosis; Prospective Studies; Renal Dialysis; Risk Factors | 2005 |
Do low doses of folic acid result in maximum lowering of homocysteine?
Topics: Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 6 | 2005 |
Chemokine RANTES is upregulated in monocytes from patients with hyperhomocysteinemia.
Topics: Adult; Chemokine CCL5; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipopolysaccharides; Male; Middle Aged; Monocytes; RNA, Messenger | 2005 |
Are homocysteine and MTHFR genotype polymorphism associated with arteriovenous fistula patency?
Topics: Arteriovenous Shunt, Surgical; Confounding Factors, Epidemiologic; Diet; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Riboflavin; Risk Factors; Thrombophilia; Thrombosis | 2005 |
Hyperhomocysteinemia and methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations in patients with inflammatory bowel disease.
Topics: Adult; Confidence Intervals; Data Interpretation, Statistical; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Inflammatory Bowel Diseases; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Odds Ratio; Prevalence; Sex Factors; Thromboembolism; Vitamin B 12 | 2005 |
Hyperhomocysteinemia in ulcerative colitis is related to folate levels.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Colitis, Ulcerative; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Thrombosis; Vitamin B 12 | 2005 |
Design and statistical issues in the homocysteinemia in kidney and end stage renal disease (HOST) study.
Topics: Adult; Cause of Death; Double-Blind Method; Folic Acid; Homocysteine; Hospitals, Veterans; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Middle Aged; Multicenter Studies as Topic; Patient Selection; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Renal Dialysis; Research Design; Treatment Outcome; Vitamin B 12 | 2004 |
B vitamins and homocysteine.
Topics: Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Stroke; Vitamin B 12; Vitamin B 6 | 2005 |
Retinal vein occlusion, homocysteine, and methylene tetrahydrofolate reductase genotype.
Topics: Aged; Case-Control Studies; DNA Mutational Analysis; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Genetic; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2005 |
Reversible nitrous oxide myelopathy and a polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase.
Topics: Anesthetics, Inhalation; Folic Acid; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitrous Oxide; Paralysis; Polymorphism, Genetic; Postoperative Complications; Spinal Cord Diseases; Vitamin B 12 | 2006 |
Erythrocyte membrane acetylcholinesterase activity in subjects with MTHFR 677C-->T genotype.
Topics: Acetylcholinesterase; Adult; Alanine; Cytidine; Erythrocyte Membrane; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Dehydrogenase (NADP); Phenylalanine | 2006 |
Plasma reduced homocysteine and other aminothiol concentrations in patients with CKD.
Topics: Adult; Aged; Atherosclerosis; Biomarkers; C-Reactive Protein; Chronic Disease; Cysteine; Dipeptides; Female; Folic Acid; Glutathione; Hemodiafiltration; Homocysteine; Humans; Hyperhomocysteinemia; Kidney; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Oxidation-Reduction; Peritoneal Dialysis; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Vitamin B 12 | 2006 |
Plasma hyperhomocysteinemia, MTHFR polymorphism and thromboembolic disease: an example of gene-nutrition interactions in chronic disease.
Topics: Chronic Disease; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Thromboembolism; Vitamin B 12; Vitamin B 6 | 2005 |
Factors involved in baseline hyperhomocysteinemia in renal transplantation.
Topics: Adult; Aged; C-Reactive Protein; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prospective Studies; Reference Values; Vitamin B 12 | 2005 |
Moderate hyperhomocysteinemia and early-onset central retinal vein occlusion.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxal Phosphate; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2006 |
Increased plasma protein homocysteinylation in hemodialysis patients.
Topics: Adult; Aged; Blood Proteins; Cardiovascular Diseases; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; In Vitro Techniques; Male; Middle Aged; Models, Molecular; Protein Binding; Protein Processing, Post-Translational; Renal Dialysis; Serum Albumin; Uremia; Vitamin B 12; Vitamin B 6; Xenobiotics | 2006 |
Splenic thrombosis in three patients with moderate hyperhomocysteinemia, low folate and the C677T variant of the methylenetetrahydrofolate reductase (MTHFR) gene.
Topics: Adolescent; Female; Folic Acid; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Risk Factors; Splenic Vein; Venous Thrombosis | 2005 |
Influence of folate on arterial permeability and stiffness in the absence or presence of hyperhomocysteinemia.
Topics: Animals; Capillary Permeability; Carotid Arteries; Cystathionine beta-Synthase; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; In Vitro Techniques; Mice; Vasoconstriction | 2006 |
[Hyperhomocysteinemia as a vascular risk factor in chronic hemodialysis patients].
Topics: Atherosclerosis; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Methylenetetrahydrofolate Reductase (NADPH2); Renal Dialysis; Risk Factors; Thrombosis; Vitamin B 12; Vitamin B Complex | 2005 |
Folic acid pretreatment prevents the reduction of Na(+),K(+)-ATPase and butyrylcholinesterase activities in rats subjected to acute hyperhomocysteinemia.
Topics: Animals; Butyrylcholinesterase; Cerebral Cortex; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances; Vitamin B Complex | 2006 |
Homocysteine and its determinants in nondialyzed chronic kidney disease patients.
Topics: Anthropometry; Case-Control Studies; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Function Tests; Linear Models; Male; Middle Aged; Nutrition Assessment; Nutritional Status; Prevalence; Vitamin B 12 | 2006 |
Use of B6 and/or folic acid fails to lower cardiovascular events.
Topics: Drug Interactions; Drug Therapy, Combination; Folic Acid; Humans; Hyperhomocysteinemia; Myocardial Infarction; Recurrence; Stroke; Vitamin B 6 | 2006 |
Total plasma homocysteine, folate, and vitamin B12 status in healthy Iranian adults: the Tehran homocysteine survey (2003-2004)/a cross-sectional population based study.
Topics: Adult; Age Factors; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Iran; Male; Middle Aged; Nutrition Surveys; Prevalence; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Homocysteine and cognitive impairment; a case series in a General Practice setting.
Topics: Acetylcysteine; Aged; Aged, 80 and over; Antioxidants; Cognition Disorders; Family Practice; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Memory Disorders; Memory, Short-Term; Radiography; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Homocysteine-lowering action is another potential cardiovascular protective factor of aged garlic extract.
Topics: Animals; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Garlic; Homocysteine; Hyperhomocysteinemia; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley | 2006 |
677TT polymorphism of methylenetetrahydrofolate reductase in combination with low serum vitamin B12 is associated with coronary in-stent restenosis.
Topics: Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Coronary Angiography; Coronary Restenosis; Female; Folic Acid; Genotype; Humans; Hyperhomocysteinemia; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Stents; Taiwan; Vitamin B 12 | 2006 |
Why is homocysteine elevated in renal failure and what can be expected from homocysteine-lowering?
Topics: Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Function Tests; Male; Prognosis; Renal Dialysis; Risk Assessment; Severity of Illness Index; Treatment Outcome; Vitamin B 6 | 2006 |
Influence of folate serum concentration on plasma homocysteine levels in HIV-positive patients exposed to protease inhibitors undergoing HAART.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cross-Sectional Studies; Female; Folic Acid; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Male; Predictive Value of Tests; Protease Inhibitors; Risk Factors; Time Factors | 2006 |
Hyperhomocysteinemia in chronic renal failure patients: relation to tissue factor and platelet aggregation.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Platelet Aggregation; Renal Dialysis; Thromboplastin; Vitamin B 12; Vitamin B 6 | 2006 |
Homocysteine trials--clear outcomes for complex reasons.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Drug Therapy, Combination; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Myocardial Infarction; Secondary Prevention; Vascular Diseases; Vitamin B 12; Vitamin B 6 | 2006 |
Hyperhomocysteinemia and low plasma folate as risk factors for central retinal vein occlusion: a case-control study in a Chinese population.
Topics: Adult; Aged; Asian People; Case-Control Studies; China; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Cystamine; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Male; Middle Aged; Radioimmunoassay; Retinal Vein Occlusion; Risk Factors | 2006 |
Hyperhomocysteinemia increases damage on brain slices exposed to in vitro model of oxygen and glucose deprivation: prevention by folic acid.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Folic Acid; Glucose; Homocysteine; Hyperhomocysteinemia; Hypoxia; Hypoxia-Ischemia, Brain; In Vitro Techniques; Lactate Dehydrogenases; Male; Rats; Rats, Wistar; Vitamin A; Vitamin B Complex | 2006 |
Hyperhomocysteinemia in patients with arterial occlusive disease.
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Risk Assessment; Risk Factors; Vitamin B 12 | 2006 |
Hyperhomocysteinemia and hypercoagulability in primary biliary cirrhosis.
Topics: Adult; Aged; Antithrombin III; Female; Folic Acid; Hemostasis; Homocysteine; Humans; Hyperhomocysteinemia; Liver Cirrhosis, Biliary; Male; Middle Aged; Peptide Hydrolases; Platelet Function Tests; Thrombomodulin; Thrombophilia; Thromboplastin; Vitamin B 12; Vitamin B 6 | 2006 |
Plasma homocysteine affects fibrin clot permeability and resistance to lysis in human subjects.
Topics: Acute Disease; Adult; Aged; Blood Coagulation; Case-Control Studies; Coronary Artery Disease; Diabetes Mellitus; Drug Resistance; Fibrin; Fibrinolytic Agents; Folic Acid; Hematinics; Homocysteine; Humans; Hypercholesterolemia; Hyperhomocysteinemia; Male; Middle Aged; Permeability; Recombinant Proteins; Tissue Plasminogen Activator | 2006 |
Hyperhomocysteinemia predicts total and cardiovascular mortality in high-risk women.
Topics: Aged; Cardiovascular Diseases; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Postmenopause; Predictive Value of Tests; Prognosis; Prospective Studies; Risk Factors; Survival Rate; Time Factors; White People | 2006 |
Kazakhstan: a folate-deficient area?
Topics: Adult; Aged; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Kazakhstan; Male; Middle Aged; Nutrition Assessment; Nutritional Status; Prevalence; Vegetables | 2006 |
Hyperhomocysteinemia can be ameliorated by dimethylsulfoniopropionate in place of folic acid in mice.
Topics: Animals; Betaine; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Hyperhomocysteinemia; Injections, Intraperitoneal; Kinetics; Male; Mice; Mice, Inbred ICR; Sulfonium Compounds | 2006 |
Effect of homocysteine lowering by 5-methyltetrahydrofolate on redox status in hyperhomocysteinemia.
Topics: Adult; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; DNA; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Sulfhydryl Compounds; Tetrahydrofolates; Vitamin B 12; Vitamin E | 2006 |
Mild hyperhomocysteinemia and the common C677T polymorphism of methylene tetrahydrofolate reductase gene are not associated with the metabolic syndrome in Type 2 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Insulin Resistance; Linear Models; Male; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Obesity; Polymorphism, Genetic; Triglycerides; Vitamin B 12 | 2006 |
Rationale and design for the CARDIOVIT Study (Cardiovit, Atherosclerotic vascular disease and hypeRhomocysteinemia: an epiDemiological study in Indians, additionally evaluating the effect of Oral VITamin supplementation).
Topics: Adult; Antioxidants; Atherosclerosis; Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Prevalence; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome; Vitamin B Complex; Vitamins | 2006 |
Total serum homocysteine, folate and vitamin B12 in a Greek school age population.
Topics: Adolescent; Adolescent Nutritional Physiological Phenomena; Age Factors; Aging; Blood Pressure; Cardiovascular Diseases; Child; Child Nutritional Physiological Phenomena; Female; Folic Acid; Greece; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Male; Reference Values; Risk Factors; Sex Factors; Social Class; Vitamin B 12; Vitamin B Complex | 2006 |
Plasma homocysteine levels and vitamin B status in patients with Pseudoexfoliation syndrome.
Topics: Aged; Exfoliation Syndrome; Eye; Female; Folic Acid; Glaucoma; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retinal Vein Occlusion; Risk Factors; Turkey; Vitamin B 12; Vitamin B 6 | 2006 |
Preoperative folate and homocysteine status in patients undergoing major surgery.
Topics: Anesthetics, Inhalation; Dietary Supplements; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Multivariate Analysis; Nitrous Oxide; Nutrition Assessment; Nutritional Status; Preoperative Care; Surveys and Questionnaires | 2006 |
Hyperhomocysteinemia and methylenetetrahydrofolate reductase polymorphism in patients with Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Reference Values; Vitamin B 12 | 2006 |
Heave-ho for homocysteine? High doses of B vitamins lower homocysteine but don't fix heart disease.
Topics: Folic Acid; Humans; Hyperhomocysteinemia; Myocardial Infarction; Stroke; Vitamin B Complex | 2006 |
Vitamin B12, folic acid, and the prevention of dementia.
Topics: Aged; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Folic Acid; Food, Fortified; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex | 2006 |
Antiphospholipid antibodies and hyperhomocysteinaemia in patients with vascular occlusive disease.
Topics: Adult; Aged; Antibodies, Antiphospholipid; Arterial Occlusive Diseases; Female; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pregnancy; Pregnancy Complications; Prevalence; Prospective Studies; Risk Factors; Thrombosis | 2006 |
Polymorphism C776G in the transcobalamin II gene and homocysteine, folate and vitamin B12 concentrations. Association with MTHFR C677T and A1298C and MTRR A66G polymorphisms in healthy children.
Topics: Brazil; Child; Child, Preschool; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Polymorphism, Genetic; Reference Values; Risk Factors; Transcobalamins; Vitamin B 12 | 2007 |
Determinants of fasting total serum homocysteine levels in liver transplant recipients.
Topics: Adult; Aged; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Liver Transplantation; Male; Middle Aged; Risk Factors | 2006 |
Hyperhomocysteinemia induces liver injury in rat: Protective effect of folic acid supplementation.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Folic Acid; Humans; Hyperhomocysteinemia; Immunohistochemistry; Liver; Male; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Superoxides | 2006 |
Homocysteine, B vitamins, and cardiovascular disease.
Topics: Cardiovascular Diseases; Dementia; Folic Acid; Humans; Hyperhomocysteinemia; Vascular Diseases; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Homocysteine, B vitamins, and cardiovascular disease.
Topics: Atherosclerosis; Cardiovascular Diseases; Folic Acid; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Homocysteine, B vitamins, and cardiovascular disease.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Data Interpretation, Statistical; Folic Acid; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Homocysteine, B vitamins, and cardiovascular disease.
Topics: Cardiovascular Diseases; Folic Acid; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Homocysteine, folate and vitamin b12 in patients with coronary heart disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Chromatography, High Pressure Liquid; Coronary Disease; Creatinine; Diet; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Vitamin B 12; Vitamin B Complex | 2006 |
Homocysteine, B vitamins, and cardiovascular disease.
Topics: Cardiovascular Diseases; Folic Acid; Humans; Hyperhomocysteinemia; India; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Homocysteine, B vitamins, and cardiovascular disease.
Topics: Cardiovascular Diseases; Clinical Trials as Topic; Data Interpretation, Statistical; Folic Acid; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Body composition: an important determinant of homocysteine and methionine concentrations in healthy individuals.
Topics: Adipose Tissue; Adult; Body Composition; Body Water; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Menopause; Methionine; Middle Aged; Muscle, Skeletal; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2007 |
G1793A polymorphisms in the methylene-tetrahydrofolate gene: effect of folic acid on homocysteine levels.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Folic Acid; Gene Frequency; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Vitamin B 12 | 2006 |
[The effect of lowering plasma homocysteine levels on some parameters of thrombotic activity in haemodialyzed patients with chronic renal failure].
Topics: Aged; Dose-Response Relationship, Drug; Female; Folic Acid; Hematologic Tests; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Reference Values; Renal Dialysis; Thrombosis; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2004 |
Nutritional determinants of plasma total homocysteine distribution in the Canary Islands.
Topics: Adolescent; Adult; Age Factors; Aged; Biomarkers; Cross-Sectional Studies; Diet; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Mental Recall; Middle Aged; Nutrition Surveys; Prevalence; Reference Values; Sex Factors; Spain; Surveys and Questionnaires; Vitamin B 12 | 2007 |
[Factors influencing homocysteineamia in type 2 diabetic patients].
Topics: Diabetes Mellitus, Type 2; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Plasma homocysteine level and myocardial infarction: how high is high enough to need intervention?
Topics: Animals; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Incidence; Myocardial Infarction; Prognosis; Risk Factors; Vitamin B Complex | 2006 |
[The treatment of hyperhomocysteinemia in patients on dialysis: folic acid or the high-flow polysulphonic membrane?].
Topics: Adult; Aged; Aged, 80 and over; Biocompatible Materials; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Membranes, Artificial; Middle Aged; Polymers; Renal Dialysis; Sulfones; Vitamin B Complex | 2006 |
Homocysteine, folic acid and B12 serum levels in pregnancy complicated with preeclampsia.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Vitamin B 12 | 2007 |
Folic acid administration and antibodies against homocysteinylated proteins in subjects with hyperhomocysteinemia.
Topics: Alleles; Autoantibodies; Case-Control Studies; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Immunoglobulin G; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2006 |
The methylenetetrahydrofolate reductase C677T gene mutation is associated with hyperhomocysteinemia, cardiovascular disease and plasma B-type natriuretic peptide levels in Korea.
Topics: Aged; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Creatine Kinase; Creatinine; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Isoenzymes; Korea; L-Lactate Dehydrogenase; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Natriuretic Peptide, Brain; Troponin I | 2006 |
Patient information. The importance of homocysteine.
Topics: Biological Availability; Cardiovascular Diseases; Causality; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Nurse Practitioners; Risk Reduction Behavior; Tetrahydrofolates | 2006 |
Homocysteine, vitamin B12 and folate levels in premature coronary artery disease.
Topics: Adult; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Risk Factors; Sex Characteristics; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Homocysteine lowering and cognitive performance.
Topics: Aged; Cognition; Cognition Disorders; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B Complex | 2006 |
[Homocysteine as a cardiovascular marker and risk factor].
Topics: Cause of Death; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Myocardial Infarction; Risk Factors; Secondary Prevention; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2006 |
Homocysteine lowering and cognitive performance.
Topics: Aged; Cognition; Cognition Disorders; Dietary Supplements; Folic Acid; Humans; Hyperhomocysteinemia; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2006 |
Hyperhomocysteinemia is associated with deep venous thrombosis of the lower extremities in Tunisian patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Leg; Male; Middle Aged; Prevalence; Recurrence; Tunisia; Venous Thrombosis; Vitamin B 12 | 2007 |
[Homocysteinemia and thrombophilic factors in unexplained decompression sickness].
Topics: Adult; Decompression Sickness; Diving; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Reference Values; Thrombophilia; Vitamin B 12 Deficiency | 2006 |
Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss.
Topics: Abortion, Habitual; Adolescent; Adult; Aged; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Risk Factors; Thrombosis; Vitamin B 12 | 2007 |
Differential effects of low and high dose folic acid on endothelial dysfunction in a murine model of mild hyperhomocysteinaemia.
Topics: Animals; Clotrimazole; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mesenteric Arteries; Methacholine Chloride; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Vasodilation; Vasodilator Agents | 2006 |
[Increase of homocysteine in cardiovascular diseases in Hungary].
Topics: Adult; Aged; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; COUP Transcription Factor II; Diabetes Mellitus, Type 2; Factor XIII; Female; Folic Acid; Homocysteine; Humans; Hungary; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Patient Selection; Polymorphism, Genetic; Retrospective Studies; Risk Factors; Vitamin B 12 | 2006 |
Total homocysteine, folate, and cobalamin, and their relation to genetic polymorphisms, lifestyle and body mass index in healthy children and adolescents.
Topics: Adolescent; Aging; Blood Pressure; Body Mass Index; Child; Child, Preschool; Cholesterol; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Sex Characteristics; Triglycerides; Vitamin B 12 | 2006 |
Hyperhomocysteinemia in a cohort of young patients with acute myocardial infarction from Western India: pattern of response to oral folic acid, vitamin B12, B6 therapy.
Topics: Administration, Oral; Adult; Cohort Studies; Female; Folic Acid; Humans; Hyperhomocysteinemia; India; Male; Myocardial Infarction; Pedigree; Treatment Outcome; Vitamin B 12; Vitamin B 6 | 2007 |
Maternal hyperhomocysteinaemia is a risk factor for congenital heart disease.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Maternal Age; Pregnancy; Pregnancy Complications; Risk Factors; Statistics, Nonparametric; Vitamin B 12 | 2006 |
Plasma homocysteine and folate levels in patients with chronic plaque psoriasis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Chronic Disease; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Psoriasis | 2006 |
Dietary intake of B-vitamins in mothers born a child with a congenital heart defect.
Topics: Adult; Case-Control Studies; Dietary Proteins; Educational Status; Female; Folic Acid; Heart Defects, Congenital; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Logistic Models; Maternal Nutritional Physiological Phenomena; Nutritional Requirements; Nutritional Status; Pregnancy; Pregnancy Complications; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2006 |
Other relevant components of nuts: phytosterols, folate and minerals.
Topics: Calcium; Cholesterol; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Intestinal Absorption; Magnesium; Minerals; Nuts; Phytosterols; Potassium; Sodium, Dietary; Trace Elements | 2006 |
13N-ammonia rest/stress PET: folic acid improves global coronary vasoreactivity in coronary artery disease patients with normal or elevated homocysteine levels.
Topics: Aged; Ammonia; Coronary Angiography; Coronary Disease; Exercise Test; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nitrogen Radioisotopes; Positron-Emission Tomography; Reference Values | 2006 |
Homocysteinylation of metallothionein impairs intracellular redox homeostasis: the enemy within!
Topics: Atherosclerosis; Betaine; Endothelium, Vascular; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Metallothionein; Oxidation-Reduction; Risk Factors; Vitamin B Complex | 2007 |
Predictive factors of hyperhomocysteinemia in HIV-positive patients.
Topics: Adult; Antiretroviral Therapy, Highly Active; Cross-Sectional Studies; Female; Folic Acid; HIV Infections; HIV Seropositivity; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged | 2007 |
Hyperhomocysteinemia as a cardiovascular risk factor in Indian women: determinants and directionality.
Topics: Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Middle Aged; Risk Assessment; Risk Factors; Vitamin B 12 | 2006 |
High prevalence of hyperhomocysteinemia in Chinese adults is associated with low folate, vitamin B-12, and vitamin B-6 status.
Topics: Adult; China; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Odds Ratio; Prevalence; Risk Factors; Seasons; Vitamin B 12; Vitamin B 6 | 2007 |
Hyperhomocysteinaemia and immune activation in patients with cancer.
Topics: Aged; Biomarkers; Case-Control Studies; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immune System; Male; Neoplasms; Neopterin; Vitamin B 12 | 2007 |
Altered renal folate handling in hypertensive patients with nephroangiosclerotic damage.
Topics: Case-Control Studies; Creatinine; Folic Acid; Genotype; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension, Renal; Ischemia; Methylenetetrahydrofolate Reductase (NADPH2); Nephrons; Renal Artery Obstruction; Vitamin B 12 | 2007 |
Evaluation of cardiovascular risk factors and related clinical markers in healthy young Japanese adults.
Topics: Adolescent; Adult; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carotid Arteries; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Japan; Regression Analysis; Risk Factors; Tunica Intima | 2007 |
[Status of homocysteine reduction in prevention of cardiovascular diseases. HOPE-2 study (Heart Outcomes Prevention Evaluation)].
Topics: Cause of Death; Drug Therapy, Combination; Folic Acid; Humans; Hyperhomocysteinemia; Multicenter Studies as Topic; Myocardial Infarction; Randomized Controlled Trials as Topic; Stroke; Survival Analysis; Vitamin B 12; Vitamin B 6 | 2007 |
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.
Topics: Animals; Brain; Disease Models, Animal; Embryo, Mammalian; Female; Ferredoxin-NADP Reductase; Folic Acid; Heart; Homocysteine; Hyperhomocysteinemia; Kidney; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine | 2007 |
Hyperhomocysteinemia and low methionine stress are risk factors for central retinal venous occlusion in an Indian population.
Topics: Adult; Case-Control Studies; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methionine; Prevalence; Prospective Studies; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2007 |
No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanese.
Topics: Adult; Aged; Atherosclerosis; Atrophy; Female; Folic Acid; Gastric Mucosa; Genotype; Helicobacter Infections; Helicobacter pylori; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Smoking | 2007 |
Low vitamin B6, and not plasma homocysteine concentration, as risk factor for abdominal aortic aneurysm: a retrospective case-control study.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Case-Control Studies; Creatinine; DNA Mutational Analysis; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B 6 Deficiency | 2007 |
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study.
Topics: Antiparkinson Agents; Carbon; Catechol O-Methyltransferase Inhibitors; Catechols; Folic Acid; Humans; Hyperhomocysteinemia; Levodopa; Nitriles; Parkinson Disease; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Time Factors; Vitamin B 12; Vitamin B 6 | 2007 |
Summaries for patients. Randomized trial of homocysteine-lowering therapy and risk for venous thromboembolism.
Topics: Aged; Female; Folic Acid; Humans; Hyperhomocysteinemia; Incidence; Male; Middle Aged; Prospective Studies; Pulmonary Embolism; Risk Factors; Thromboembolism; Venous Thrombosis; Vitamin B 12; Vitamin B 6 | 2007 |
Short-term hyperhomocysteinemia-induced oxidative stress activates retinal glial cells and increases vascular endothelial growth factor expression in rat retina.
Topics: alpha-Tocopherol; Animals; Folic Acid; Glial Fibrillary Acidic Protein; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Male; Neuroglia; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Retina; Scavenger Receptors, Class E; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Vascular Endothelial Growth Factor A; Vimentin; Vitamin A | 2007 |
Can B vitamin therapy help to prevent future vascular events?
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12 | 2007 |
Antiepileptic drugs and MTHFR polymorphisms influence hyper-homocysteinemia recurrence in epileptic patients.
Topics: Adult; Age Factors; Anticonvulsants; Combined Modality Therapy; Epilepsy; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome | 2007 |
Subclinical hypothyroidism, hyperhomocysteinemia and dyslipidemia: investigating links with ischemic stroke in Turkish patients.
Topics: Aged; Dyslipidemias; Female; Folic Acid; Humans; Hyperhomocysteinemia; Immunoassay; Ischemia; Male; Middle Aged; Risk Factors; Statistics, Nonparametric; Thyrotropin; Turkey; Vitamin B 12 | 2007 |
Mild hyperhomocysteinemia and low folate concentrations as risk factors for cervical arterial dissection.
Topics: Adolescent; Adult; Carotid Artery, Internal, Dissection; Case-Control Studies; Cerebral Arteries; Cerebral Infarction; Fasting; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Middle Aged; Nutritional Status; Odds Ratio; Polymorphism, Genetic; Prospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Vertebral Artery Dissection; Vitamin B 12 | 2007 |
Hyperhomocysteinemia in winter elite athletes: a longitudinal study.
Topics: Adult; Cardiovascular Diseases; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Physical Exertion; Prevalence; Risk Factors; Seasons; Sex Distribution; Sports | 2007 |
Correlations between folate, B12, homocysteine levels, and radiological markers of neuropathology in elderly post-stroke patients.
Topics: Aged; Biomarkers; Brain; Brain Infarction; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Mental Recall; Nutrition Assessment; Nutrition Policy; Stroke; Surveys and Questionnaires; Vitamin B 12; Vitamin B Complex | 2007 |
The use of an in vivo model to study the effects of hyperhomocysteinaemia on vascular function.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Folic Acid; Hyperhomocysteinemia; Male; Methionine; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Does lowering hyperhomocysteinemia by folic acid beneficial for oculo-Behcet's disease? A pilot study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Behcet Syndrome; Cyclophosphamide; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Male; Middle Aged; Pilot Projects; Prospective Studies; Retinal Vasculitis; Uveitis; Visual Acuity; Vitamin B Complex | 2007 |
Folic acid and cognitive function: what is the final verdict?
Topics: Aged; Clinical Trials as Topic; Cognition; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Randomized Controlled Trials as Topic | 2007 |
B-vitamins and homocysteine in Spanish institutionalized elderly.
Topics: Aged; Aged, 80 and over; Aging; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Institutionalization; Male; Middle Aged; Regression Analysis; Sex Characteristics; Spain; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamin B Deficiency | 2007 |
Homocysteine (Hcy) follow-up study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2007 |
Experimental hyperhomocysteinemia disturbs bone metabolism in rats.
Topics: Animals; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Collagen Type I; Creatine; Female; Folic Acid; Homocysteine; Hydroxyproline; Hyperhomocysteinemia; Methionine; Osteocalcin; Osteogenesis; Peptides; Rats; Rats, Wistar; Vitamin B 12 | 2007 |
Homocysteine in restless legs syndrome.
Topics: Aged; Antiparkinson Agents; Catechols; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Reference Values; Restless Legs Syndrome; Vitamin B 12; Vitamin B 6 | 2008 |
Effect of MTHFR polymorphisms on hyperhomocysteinemia in levodopa-treated Parkinsonian patients.
Topics: Aged; Antiparkinson Agents; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; Vitamin B 12 | 2007 |
Efficacy of folic acid in children with migraine, hyperhomocysteinemia and MTHFR polymorphisms.
Topics: Adolescent; Child; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Migraine Disorders; Polymorphism, Genetic; Treatment Outcome | 2007 |
Concurrent folate treatment prevents Na+,K+-ATPase activity inhibition and memory impairments caused by chronic hyperhomocysteinemia during rat development.
Topics: Aging; Animals; Chronic Disease; Cognition; Folic Acid; Homocysteine; Hyperhomocysteinemia; Male; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Motor Activity; Nerve Tissue Proteins; Parietal Lobe; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Space Perception; Synaptic Membranes; Thiobarbituric Acid Reactive Substances; Vitamins | 2007 |
The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels.
Topics: Aged; Coronary Artery Disease; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Turkey; Vitamin B 12 | 2008 |
Hyperhomocysteinemia is associated with cognitive impairment in multiple sclerosis.
Topics: Age of Onset; Brain; Cognition Disorders; Disability Evaluation; Disease Progression; Folic Acid; Homocysteine; Hyperhomocysteinemia; Multiple Sclerosis; Multivariate Analysis; Neuropsychological Tests; Predictive Value of Tests; Up-Regulation; Vitamin B 12 Deficiency | 2008 |
Effect of folate, vitamin B6, and vitamin B12 intake and MTHFR C677T polymorphism on homocysteine concentrations of renal transplant recipients.
Topics: Cross-Sectional Studies; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Kidney Transplantation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Postoperative Complications; Vitamin B 12; Vitamin B 6 | 2007 |
Is homocysteine toxic in uremia?
Topics: Acetylcysteine; Antitoxins; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Myocardial Infarction; Recurrence; Reference Values; Renal Dialysis; Retrospective Studies; Risk Factors; Uremia | 2008 |
Homocysteine levels in epileptic children receiving antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Oxcarbazepine; Valproic Acid; Vitamin B 12 | 2007 |
Effect of folate on neointima formation and matrix metalloproteinase-9 expression after balloon injury in hyperhomocysteinemic rabbits.
Topics: Animals; Aorta, Abdominal; Catheterization; Folic Acid; Gene Expression Regulation, Enzymologic; Hyperhomocysteinemia; Male; Matrix Metalloproteinase 9; Rabbits; Tunica Intima | 2008 |
A comparison of some of the cardiovascular risk factors in vegetarian and omnivorous Turkish females.
Topics: Adult; Cardiovascular Diseases; Diet; Diet Records; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Nutritional Status; Risk Factors; Turkey; Vitamin B 12 | 2008 |
Elevated plasma homocysteine levels in patients with amyotrophic lateral sclerosis.
Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Biomarkers; Central Nervous System; Comorbidity; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nerve Degeneration; Predictive Value of Tests; Risk Factors; Sensitivity and Specificity; Up-Regulation; Vitamin B 12 | 2008 |
Homocysteinemia correlates with plasma thiol redox status in patients with end-stage renal disease.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cysteine; Dialysis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Oxidation-Reduction; Statistics, Nonparametric; Sulfhydryl Compounds; Vitamin B Complex | 2008 |
Sport-related hyperhomocysteinaemia: a putative marker of muscular demand to be noted for cardiovascular risk.
Topics: Adult; Cardiovascular Diseases; Case-Control Studies; Cholesterol, HDL; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Interleukin-6; L-Lactate Dehydrogenase; Male; Muscle, Skeletal; Risk Factors; Sports; Vitamin B 12 | 2008 |
Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Chromatography, High Pressure Liquid; Electrochemistry; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Valproic Acid; Vitamin B 12 | 2008 |
Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Diet Records; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Risk Factors; Transcobalamins; Vitamin B 12; Vitamin B 6; Vitamin B 6 Deficiency; Vitamin B Complex | 2008 |
Homocysteine competes for the peroxisome proliferator-activated receptor nuclear receptors.
Topics: Diabetes Mellitus, Type 2; Diet; Folic Acid; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Peroxisome Proliferator-Activated Receptors; Rosiglitazone; Thiazolidinediones | 2008 |
Protective effect against alcohol dependence of the thermolabile variant of MTHFR.
Topics: Alcohol Drinking; Alcoholic Neuropathy; Alcoholism; Control Groups; Female; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Vitamin B 12 | 2008 |
High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiotonic Agents; Coronary Occlusion; Drug Evaluation, Preclinical; Endothelium, Vascular; Folic Acid; Hyperhomocysteinemia; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Premedication; Prodrugs; Purines; Rats; Rats, Wistar; Superoxides | 2008 |
How does folic acid cure heart attacks?
Topics: Adenosine Triphosphate; Animals; Carbon; Cardiotonic Agents; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Methylation; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Oxidative Stress; Prodrugs; Purines; Rats; Tetrahydrofolates | 2008 |
Hopeful for a second HOPE-2 post hoc analysis.
Topics: Chronic Disease; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Randomized Controlled Trials as Topic; Vitamin B Complex | 2008 |
Homocysteine, folate and cognition in a large community-based sample of elderly people--the 3C Dijon Study.
Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; France; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neuropsychological Tests; Prospective Studies; Residence Characteristics; Risk Factors; Urban Health | 2008 |
Post-methionine load test: A more sensitive tool to reveal hyperhomocysteinemia in Alzheimer patients?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Sensitivity and Specificity | 2008 |
[Hyperhomocysteinemia complicated by myocardial infarction and portal vein thrombosis--case report].
Topics: Female; Folic Acid; Humans; Hyperhomocysteinemia; Middle Aged; Myocardial Infarction; Portal Vein; Thrombosis; Treatment Outcome; Vitamin B 12 | 2006 |
Cryptogenic stroke in a boy with atrial septal defect and hyperhomocysteinemia.
Topics: Adolescent; Age of Onset; Anticoagulants; Blood Coagulation Disorders, Inherited; Cerebral Arteries; Diffusion Magnetic Resonance Imaging; Folic Acid; Genetic Predisposition to Disease; Heart Septal Defects, Atrial; Hemianopsia; Humans; Hyperhomocysteinemia; Infarction, Posterior Cerebral Artery; Intracranial Embolism; Male; Occipital Lobe; Stroke; Vitamin B 12 | 2008 |
The homocysteine paradox.
Topics: Animals; Arginine; Cardiovascular Diseases; Cystatin C; Cystatins; Disease Models, Animal; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
The diagnostic value of serum homocysteine concentration as a risk factor for coronary artery disease.
Topics: Coronary Disease; Demography; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Lipids; Lipoproteins; Male; Middle Aged; Odds Ratio; Retrospective Studies; Risk Factors; ROC Curve; Surveys and Questionnaires; Vitamin B 12 | 1998 |
[The recommended daily intake of folic acid is insufficient for optimum homocysteine level].
Topics: Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia | 1998 |
Venous thrombosis and hyperhomocysteinaemia.
Topics: Adult; Anticoagulants; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Recurrence; Risk Factors; Venous Thrombosis; Vitamin B 12 | 1998 |
Homocysteine and folate in healthy east London Bangladeshis.
Topics: Adult; Aged; Bangladesh; Case-Control Studies; Chromatography, High Pressure Liquid; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; London; Male; Middle Aged; White People | 1998 |
Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation.
Topics: Adult; Endothelium, Vascular; Female; Fibronectins; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Pre-Eclampsia; Pregnancy; Risk Factors | 1998 |
Modulatory impact of cardiac rehabilitation on hyperhomocysteinemia in patients with coronary artery disease and "normal" lipid levels.
Topics: Aged; Coronary Disease; Exercise; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Treatment Outcome | 1998 |
Endothelial dysfunction by acute hyperhomocyst(e)inaemia: restoration by folic acid.
Topics: Acute Disease; Adult; Brachial Artery; Endothelium, Vascular; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methionine; Vasodilation | 1999 |
Response of hyperhomocysteinemia to folic acid supplementation in patients with end-stage renal disease.
Topics: Adult; Erythrocytes; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Middle Aged; Peritoneal Dialysis; Renal Dialysis | 1999 |
Do you need this heart disease test?
Topics: Cardiovascular Diseases; Folic Acid; Heart Diseases; Humans; Hyperhomocysteinemia; Nutrition Policy; Pyridoxine; Risk Factors | 1999 |
Prevalence and determinants of hyperhomocysteinemia in hemodialysis and peritoneal dialysis.
Topics: Creatinine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Peritoneal Dialysis; Prevalence; Pyridoxine; Renal Dialysis; Smoking; Time Factors; Vitamin B 12 | 1999 |
How folate fights disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Enzyme Stability; Female; Flavin-Adenine Dinucleotide; Folic Acid; Genetics, Population; Homozygote; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Recombinant Proteins | 1999 |
The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Escherichia coli; Flavin-Adenine Dinucleotide; Folic Acid; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Models, Molecular; Molecular Sequence Data; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Protein Conformation; Recombinant Proteins; Structure-Activity Relationship; X-Ray Diffraction | 1999 |
Combination of low-dose folic acid and pyridoxine for treatment of hyperhomocysteinaemia in patients with premature arterial disease and their relatives.
Topics: Adult; Age of Onset; Arteriosclerosis; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Prospective Studies; Pyridoxine; Risk Factors | 1999 |
Thermolabile methyltetrahydrofolate reductase associated with unusual venous and arterial thromboses.
Topics: Adult; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Thrombosis; Venous Thrombosis | 1999 |
Coronary artery disease and homocysteine: a case study.
Topics: Coronary Disease; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors | 1999 |
Homocysteine and arteriosclerosis: subclinical and clinical disease associations.
Topics: Adolescent; Adult; Animals; Arteriosclerosis; Child; Child, Preschool; Comorbidity; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Middle Aged; Prevalence; Primates; Risk Factors; Swine; Swine, Miniature; Thrombophilia | 1999 |
Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
Topics: Adult; Aged; Amino Acid Substitution; Arteriosclerosis; Carotid Arteries; Carotid Stenosis; Comorbidity; Diet; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Health Surveys; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Obesity; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Pyridoxine; Risk Factors; Smoking; Tunica Intima; Ultrasonography; Vitamin B 12; Western Australia | 1999 |
Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.
Topics: Adult; Age Factors; Amino Acid Substitution; Arteriosclerosis; Body Mass Index; Comorbidity; Fasting; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Lipids; Male; Menopause; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pyridoxine; Smoking; Vitamin B 12 | 1999 |
[Obstetric problems followed by stroke].
Topics: Abortion, Habitual; Adult; Arteriosclerosis; Cerebral Infarction; Diagnosis, Differential; Female; Fetal Death; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Male; Methionine; Nutrition Disorders; Placental Insufficiency; Pregnancy; Pregnancy Complications, Cardiovascular; Pyridoxine; Smoking; Venous Thrombosis; Vitamin B 6 Deficiency | 1999 |
Hyperhomocyst(e)inemia--determining factors and treatment.
Topics: Animals; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Cricetinae; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pyridoxine; Risk Factors; Vitamin B 12 | 1999 |
Effect of usual doses of folate supplementation on elevated plasma homocyst(e)ine in hemodialysis patients: no difference between 1 and 5 mg daily.
Topics: Aged; Arteriosclerosis; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors | 1999 |
Effects of folate supplementation in hyperhomocysteinemic pigs.
Topics: Animals; Arteries; Dietary Supplements; Female; Folic Acid; Hyperhomocysteinemia; Hyperplasia; Male; Swine | 1999 |
Prevalence of mild fasting hyperhomocysteinemia in renal transplant versus coronary artery disease patients after fortification of cereal grain flour with folic acid.
Topics: Coronary Disease; Fasting; Female; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Male; Middle Aged; Vitamin B 12 | 1999 |
Normohomocysteinaemia and vitamin-treated hyperhomocysteinaemia are associated with similar risks of cardiovascular events in patients with premature peripheral arterial occlusive disease. A prospective cohort study.
Topics: Adult; Age of Onset; Aged; Arterial Occlusive Diseases; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Pyridoxine; Risk; Risk Factors | 1999 |
A common mutation in the methylenetetrahydrofolate reductase gene is a determinant of hyperhomocysteinemia in epileptic patients receiving anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Folic Acid; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation | 1999 |
Molecular basis for methionine synthase reductase deficiency in patients belonging to the cblE complementation group of disorders in folate/cobalamin metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; DNA Mutational Analysis; DNA, Complementary; Enzyme Activation; Ferredoxin-NADP Reductase; Folic Acid; Genes, Recessive; Genetic Complementation Test; Heteroduplex Analysis; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Mutation; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA Splicing; Sequence Analysis, DNA; Vitamin B 12 | 1999 |
Folic acid fortification.
Topics: Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Vitamin B Complex | 1999 |
Hyperhomocyst(e)inemia and the prevalence of atherosclerotic vascular disease in patients with end-stage renal disease.
Topics: Aged; Arteriosclerosis; Coronary Artery Disease; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Odds Ratio; Renal Dialysis; Retrospective Studies; Risk Factors; Sex Factors; Vitamin B 12 | 1999 |
[Atherosclerosis. Congress of the European Atherosclerosis Society (EAS), Athens (Greece), 26-29 May 1999].
Topics: Anticholesteremic Agents; Antioxidants; Arteriosclerosis; Ascorbic Acid; Cholesterol, LDL; Diet; Europe; Folic Acid; Greece; Humans; Hyperhomocysteinemia; Lipoproteins; Pravastatin; Pyridoxine; Risk Factors; Societies, Medical; Triglycerides | 1999 |
Treatment of hyperhomocysteinemia with folic acid and vitamins B12 and B6 attenuates thrombin generation.
Topics: Adult; Cysteine; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pyridoxine; Thrombin; Thrombin Time; Vitamin B 12 | 1999 |
Hyperhomocyst(e)inemia is associated with carotid atherosclerosis.
Topics: Age Factors; Body Mass Index; Carotid Artery Diseases; Carotid Artery, Common; Carotid Artery, Internal; Chromatography, High Pressure Liquid; Creatinine; Diabetes Complications; Female; Fluorescence; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Logistic Models; Male; Middle Aged; Regression Analysis; Risk Factors; Sex Factors; Smoking; Tunica Intima; Tunica Media; Ultrasonography; Vitamin B 12 | 1999 |
Extracellular magnesium regulates effects of vitamin B6, B12 and folate on homocysteinemia-induced depletion of intracellular free magnesium ions in canine cerebral vascular smooth muscle cells: possible relationship to [Ca2+]i, atherogenesis and stroke.
Topics: Animals; Arteriosclerosis; Basilar Artery; Calcium; Cells, Cultured; Cerebral Arteries; Dogs; Folic Acid; Homocysteine; Hyperhomocysteinemia; Magnesium; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Pyridoxine; Signal Transduction; Stroke; Vitamin B 12; Vitamins | 1999 |
Three months supplementation of hyperhomocysteinaemic patients with folic acid and vitamin B6 improves biological markers of endothelial dysfunction.
Topics: Adult; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pyridoxine; Risk Factors; Thrombomodulin; Vascular Diseases; von Willebrand Factor | 1999 |
Effect of short-term vitamin (folic acid, vitamins B6 and B12) administration on endothelial dysfunction induced by post-methionine load hyperhomocysteinemia.
Topics: Administration, Oral; Adult; Blood Flow Velocity; Drug Therapy, Combination; Endothelium, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxine; Treatment Outcome; Vasodilation; Vitamin B 12 | 1999 |
[Left branch portal vein thrombosis associated with hyperhomocysteinemia].
Topics: Adult; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Portal Vein; Venous Thrombosis | 1999 |
Erythropoietin, folic acid deficiency and hyperhomocysteinemia: is there a possible relationship in chronically hemodialyzed patients?
Topics: Analysis of Variance; Case-Control Studies; Cross-Sectional Studies; Erythropoietin; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prospective Studies; Recombinant Proteins; Renal Dialysis | 2000 |
Hyperhomocysteinaemia: a risk factor for vascular disease.
Topics: Comorbidity; Dietary Supplements; Folic Acid; Homocystine; Humans; Hyperhomocysteinemia; Risk Factors; Vascular Diseases | 1999 |
Endpoints for homocysteine-lowering trials.
Topics: Adult; Aged; Child; Coronary Artery Disease; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Pyridoxine | 2000 |
Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men.
Topics: Case-Control Studies; Coronary Disease; Europe; Fasting; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Risk Factors; United Kingdom; Vitamin B 12 | 2000 |
Low plasma folate in combination with the 677 C-->T methylenetetrahydrofolate reductase polymorphism is associated with increased risk of coronary artery disease in Koreans.
Topics: Adult; Aged; Asian People; Cardiac Catheterization; Coronary Disease; Female; Folic Acid; Gene Frequency; Homocysteine; Humans; Hyperhomocysteinemia; Korea; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors; Sex Factors; Vitamin B 12 | 2000 |
Plasma total homocysteine levels in subjects with hyperinsulinemia.
Topics: Adult; Aged; Blood Glucose; Coronary Disease; Cross-Sectional Studies; Female; Folic Acid; Glucose Tolerance Test; Homocysteine; Humans; Hyperhomocysteinemia; Hyperinsulinism; Insulin; Insulin Resistance; Life Style; Linear Models; Male; Middle Aged; Risk Factors | 2000 |
Treatment with different doses of folic acid in haemodialysis patients: effects on folate distribution and aminothiol concentrations.
Topics: Biomarkers; Cysteine; Dose-Response Relationship, Drug; Erythrocytes; Female; Folic Acid; Glutathione; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Pteroylpolyglutamic Acids; Renal Dialysis; Renal Insufficiency; Treatment Outcome | 2000 |
Normohomocysteinaemia and vitamin-treated hyperhomocysteinaemia are associated with similar risks of cardiovascular events in patients with premature atherothrombotic cerebrovascular disease. A prospective cohort study.
Topics: Adult; Arteriosclerosis; Female; Folic Acid; Follow-Up Studies; Hematinics; Humans; Hyperhomocysteinemia; Ischemic Attack, Transient; Male; Mass Screening; Methionine; Middle Aged; Proportional Hazards Models; Prospective Studies; Pyridoxine; Risk Assessment; Risk Factors; Stroke; Treatment Outcome | 2000 |
[Effect of folates, vitamin B12 and life style factors on mild hyperhomocysteinemia in a population sample].
Topics: Alcohol Drinking; Exercise; Female; Folic Acid; Humans; Hyperhomocysteinemia; Life Style; Male; Middle Aged; Risk Factors; Smoking; Vitamin B 12 | 1999 |
Methylenetetrahydrofolate reductase deficiency in four siblings: a clinical, biochemical, and molecular study of the family.
Topics: Adolescent; Amino Acid Substitution; Child; Child, Preschool; Diseases in Twins; Enzyme Stability; Exons; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Nuclear Family; Oxidoreductases Acting on CH-NH Group Donors; Pedigree; Polymorphism, Genetic; Prenatal Diagnosis | 2000 |
Plasma homocysteine levels in renal transplanted patients on cyclosporine or tacrolimus therapy: effect of treatment with folic acid.
Topics: Analysis of Variance; Case-Control Studies; Cholesterol; Creatinine; Cyclosporine; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Linear Models; Male; Middle Aged; Multivariate Analysis; Risk Factors; Tacrolimus; Triglycerides; Vitamin B 12 | 2000 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Effect of chronic alcohol consumption on total plasma homocysteine level in rats.
Topics: Alcohol Drinking; Animals; Folic Acid; Hematinics; Homocysteine; Hyperhomocysteinemia; Male; Pyridoxine; Rats; Rats, Sprague-Dawley; Vitamin B 12 | 2000 |
The role of vitamin B12 in fasting hyperhomocysteinemia and its interaction with the homozygous C677T mutation of the methylenetetrahydrofolate reductase (MTHFR) gene. A case-control study of patients with early-onset thrombotic events.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Age of Onset; Aged; Amino Acid Substitution; Case-Control Studies; Fasting; Female; Folic Acid; Gene Frequency; Genetic Heterogeneity; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors; Sex Factors; Tetrahydrofolates; Thrombophilia; Thrombosis; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Children with stroke: polymorphism of the MTHFR gene, mild hyperhomocysteinemia, and vitamin status.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Cytosine; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Hyperhomocysteinemia; Infant; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Pyridoxine; Secondary Prevention; Stroke; Thymidine; Vitamin B 12; Vitamins | 2000 |
Homocysteine and heart disease in Indian Asians.
Topics: Coronary Disease; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; India; Risk Factors; United Kingdom; Vitamin B 12 | 2000 |
Homocysteine and heart disease in Indian Asians.
Topics: Coronary Disease; Folic Acid; Folic Acid Deficiency; Fructose; Homocysteine; Humans; Hyperhomocysteinemia; India; Malabsorption Syndromes; United Kingdom; Vitamin B 12 | 2000 |
[Sulphur amino acids, vitamin B12 and folic acid in children with chronic renal failure].
Topics: Adolescent; Adult; Amino Acids, Sulfur; Child; Folic Acid; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Renal Dialysis; Vitamin B 12 | 2000 |
The effect of different treatment regimens in reducing fasting and postmethionine-load homocysteine concentrations.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Pyridoxine; Risk Factors | 2000 |
Hyperhomocysteinemia in liver transplant recipients: prevalence and multivariate analysis of predisposing factors.
Topics: Creatinine; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Liver Transplantation; Male; Middle Aged; Multivariate Analysis; Postoperative Complications; Prevalence; Risk Factors; Treatment Outcome | 2000 |
Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Folic Acid; Food, Formulated; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Thrombomodulin; Vasodilator Agents | 2000 |
The (non-)sense of the methionine loading test for detecting hyperhomocysteinaemia.
Topics: Cardiovascular Diseases; Fasting; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Mass Screening; Methionine | 2000 |
Homocysteine elevation in sickle cell disease.
Topics: Adolescent; Adult; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Hemoglobin SC Disease; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Requirements; Pilot Projects; Vitamin B 12 | 2000 |
[Homocysteine and its metabolites in chronic renal insufficiency and the effect of a vitamin replacement].
Topics: Adult; Aged; Arteriosclerosis; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methionine; Middle Aged; Pyridoxine; Renal Dialysis; Severity of Illness Index; Vitamin B 12; Vitamin B Complex | 2000 |
The effect of C677T mutation of methylene tetrahydrofolate reductase gene and plasma folate level on hyperhomocysteinemia in patients with meningomyelocele.
Topics: Alleles; Asian People; Child; Female; Folic Acid; Gene Expression; Genotype; Heterozygote; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Meningomyelocele; Methylenetetrahydrofolate Dehydrogenase (NADP); Point Mutation; Polymerase Chain Reaction | 2000 |
Comment: treatment of hyperhomocysteinemia with folic acid.
Topics: Cognition Disorders; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Risk Factors | 2000 |
Hyperhomocyst(e)inemia, MTHFR 677C-->T polymorphism and folate status in acute coronary disease.
Topics: Acute Disease; Coronary Disease; Folic Acid; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic | 2000 |
Determinants of plasma total homocysteine levels in Korean chronic renal transplant recipients.
Topics: Adult; Aged; Cardiovascular Diseases; Creatinine; Cross-Sectional Studies; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Kidney Transplantation; Korea; Male; Middle Aged; Prevalence; Pyridoxal Phosphate; Serum Albumin; Vitamin B 12 | 2000 |
Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia.
Topics: Aged; Alleles; Alternative Splicing; Animals; Antigens, Surface; Carboxypeptidases; Cloning, Molecular; COS Cells; DNA Mutational Analysis; Folic Acid; Glutamate Carboxypeptidase II; Homocysteine; Humans; Hyperhomocysteinemia; Intestinal Absorption; Isoenzymes; Jejunum; Middle Aged; Molecular Sequence Data; Polymorphism, Genetic; RNA, Messenger; Sequence Analysis, DNA; Transfection; White People | 2000 |
Vitamin B-12 deficiency and hyperhomocysteinemia are partly ameliorated by cobalt and nickel supplementation in pigs.
Topics: Animal Feed; Animals; Cobalt; Copper; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Homocysteine; Hyperhomocysteinemia; Iron; Liver; Male; Nickel; Swine; Trace Elements; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Serum total homocysteine concentration is related to self-reported heart attack or stroke history among men and women in the NHANES III.
Topics: Adult; Age Factors; Aged; Female; Folic Acid; Heart Arrest; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutrition Surveys; Risk Factors; Self Disclosure; Sex Factors; Stroke; Vitamin B 12 | 2000 |
Blood homocysteine and vitamin B levels are not associated with cognitive skills in healthy normally ageing subjects.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cognition; Dementia; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Risk Factors; Vitamin B 12 | 2000 |
Hyperhomocysteinemia in renal transplant recipients with cyclosporine.
Topics: Cyclosporine; Erythrocytes; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Reference Values; Vitamin B 12 | 2000 |
Hyperhomocysteinemia in type 2 diabetes: relationship to macroangiopathy, nephropathy, and insulin resistance.
Topics: Aged; Cohort Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Logistic Models; Male; Metabolic Clearance Rate; Metformin; Middle Aged; Vitamin B 12 | 2000 |
Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury.
Topics: Administration, Oral; Angioplasty, Balloon; Animals; Carotid Arteries; Carotid Artery Diseases; Cystine; Diet; Dose-Response Relationship, Drug; Folic Acid; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Male; Methionine; Rats; Rats, Sprague-Dawley; Tunica Intima; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Is there a role of cyclosporine A on total homocysteine export from human renal proximal tubular epithelial cells?
Topics: Biological Transport, Active; Cells, Cultured; Cyclosporine; Epithelial Cells; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubules, Proximal; Methionine; Pyridoxine; Vitamin B 12 | 2001 |
5,10-methylenetetrahydrofolate reductase common mutations, folate status and plasma homocysteine in healthy French adults of the Supplementation en Vitamines et Mineraux Antioxydants (SU.VI.MAX) cohort.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Cohort Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation, Missense; Oxidoreductases; Polymorphism, Genetic; Sex Factors | 2000 |
Supplementation of atherogenic diet with B vitamins does not prevent atherosclerosis or vascular dysfunction in monkeys.
Topics: Animals; Arteriosclerosis; Blood Coagulation; Carotid Arteries; Cholesterol; Diet, Atherogenic; Dietary Supplements; Disease Models, Animal; Folic Acid; Hypercholesterolemia; Hyperhomocysteinemia; In Vitro Techniques; Macaca fascicularis; Partial Thromboplastin Time; Pyridoxine; Thrombin; Treatment Outcome; Vascular Diseases; Vasodilation; Vasodilator Agents; Vitamin B 12 | 2001 |
Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers.
Topics: Animals; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Lipid Peroxides; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2001 |
Effects of methionine loading on plasma and erythrocyte sulphur amino acids and sulph-hydryls before and after co-factor supplementation in haemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids, Sulfur; Case-Control Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Pyridoxine; Renal Dialysis; Sulfhydryl Compounds | 2001 |
Plasma folate, vitamin B(12), and homocyst(e)ine concentrations in preeclamptic and normotensive Peruvian women.
Topics: Adult; Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Logistic Models; Odds Ratio; Peru; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Surveys and Questionnaires; Vitamin B 12 | 2001 |
Unsuspected hyperhomocysteinemia in chronically anticoagulated patients.
Topics: Aged; Anticoagulants; Case-Control Studies; Chronic Disease; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Vegetables; Vitamin K | 2001 |
Lifestyle effects on homocysteine and an alcohol paradox.
Topics: Aged; Aging; Alcohol Drinking; Animals; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Male | 2001 |
Mild hyperhomocyst(e)inemia: a possible risk factor for cervical artery dissection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Carotid Artery, Internal, Dissection; Comorbidity; Disease Susceptibility; Female; Folic Acid; Genotype; Homocysteine; Homocystine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Vertebral Artery Dissection; Vitamin B 12 | 2001 |
Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Cells, Cultured; Diet; Disease Models, Animal; Folic Acid; Humans; Hyperhomocysteinemia; Immunohistochemistry; Male; Matrix Metalloproteinase 9; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridoxine; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thromboplastin; Vascular Cell Adhesion Molecule-1; Vasculitis; Vitamin B 12 | 2001 |
Effective treatment of hyperhomocysteinemia in heart transplant recipients with and without renal failure.
Topics: Adult; Algorithms; Creatinine; Female; Folic Acid; Heart Transplantation; Humans; Hyperhomocysteinemia; Kidney Function Tests; Male; Middle Aged; Pyridoxine; Renal Insufficiency | 2001 |
Hyperhomocysteinemia in Greek patients with inflammatory bowel disease.
Topics: Adult; Aged; Colitis, Ulcerative; Crohn Disease; Female; Folic Acid; Greece; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Risk Factors; Thrombosis | 2000 |
Folic acid: miscarriages, anomalies, thromboses, cancers.
Topics: Adolescent; Adult; Alcoholism; Child; Child, Preschool; Congenital Abnormalities; Diet; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Risk Factors; Thrombosis | 2001 |
Anti-epileptic drug treatment in children: hyperhomocysteinaemia, B-vitamins and the 677C-->T mutation of the methylenetetrahydrofolate reductase gene.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Valproic Acid | 2000 |
Racial variation in fasting and random homocysteine levels.
Topics: Black People; Blood Urea Nitrogen; Body Mass Index; Creatinine; Fasting; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; New York City; Personnel, Hospital; Random Allocation; Reference Values; Time Factors; Vitamin B 12; White People | 2001 |
Non-pregnant circulatory volume status predicts subsequent pregnancy outcome in normotensive thrombophilic formerly preeclamptic women.
Topics: Aspirin; Birth Weight; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; HELLP Syndrome; Heparin, Low-Molecular-Weight; Humans; Hyperhomocysteinemia; Hypertension; Plasma Volume; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Complications, Hematologic; Pregnancy Outcome; Thrombophilia | 2001 |
Homocysteine, vitamin B12, serum and erythrocyte folate in peritoneal dialysis patients.
Topics: Aged; Cross-Sectional Studies; Erythrocytes; Female; Folic Acid; Homocysteine; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Peritoneal Dialysis; Vitamin B 12 | 2001 |
Effect of folic acid treatment on endothelium-dependent vasodilation and nitric oxide-derived end products in hyperhomocysteinemic subjects.
Topics: Adult; Aged; Case-Control Studies; Cholesterol; Endothelium, Vascular; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Male; Microcirculation; Middle Aged; Nitric Oxide; Skin; Vasodilation | 2001 |
Renal insufficiency, vitamin B(12) status, and population attributable risk for mild hyperhomocysteinemia among coronary artery disease patients in the era of folic acid-fortified cereal grain flour.
Topics: Adult; Aged; Coronary Artery Disease; Coronary Disease; Creatinine; Edible Grain; Female; Flour; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vitamin B 12 | 2001 |
Influence of vitamin-optimized plasma homocysteine cutoff values on the prevalence of hyperhomocysteinemia in healthy adults.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Prevalence; Pyridoxine; Vitamin B 12; Vitamins | 2001 |
The history of folic acid.
Topics: Anemia; Brain Diseases; Colonic Neoplasms; Female; Folic Acid; Folic Acid Deficiency; History, 20th Century; Humans; Hyperhomocysteinemia; Methotrexate; Neural Tube Defects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Pregnancy Complications, Hematologic; Vascular Diseases; Vitamin B 12 Deficiency | 2001 |
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Betaine; Betaine-Homocysteine S-Methyltransferase; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methyltransferases; Middle Aged; Peritoneal Dialysis; Predictive Value of Tests; Pyridoxine; Renal Dialysis; Sarcosine; Uremia; Vitamin B 12; Zinc | 2001 |
Plasma proteins containing damaged L-isoaspartyl residues are increased in uremia: implications for mechanism.
Topics: Aspartic Acid; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Folic Acid; Hematinics; Homocysteine; Humans; Hyperhomocysteinemia; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Renal Dialysis; S-Adenosylhomocysteine; Serum Albumin; Uremia | 2001 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
Relationship between plasma homocysteine and vitamin status in the Framingham study population. Impact of folic acid fortification.
Topics: Aged; Aged, 80 and over; Carotid Stenosis; Cohort Studies; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Odds Ratio; Risk; United States; Vitamin B Complex | 2000 |
Hyperhomocysteinaemia and MTHFR C677T gene polymorphism in renal transplant recipients.
Topics: Adolescent; Adult; Alleles; Analysis of Variance; Case-Control Studies; Child; Cholesterol; Creatinine; Female; Fluorescence Polarization Immunoassay; Folic Acid; Genotype; Humans; Hyperhomocysteinemia; Immunoenzyme Techniques; Kidney Failure, Chronic; Kidney Transplantation; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Time Factors | 2001 |
Hyperhomocyst(e)inaemia, but not MTHFR C677T mutation, as a risk factor for non-arteritic ischaemic optic neuropathy.
Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Optic Neuropathy, Ischemic; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors; Vitamin B 12 | 2001 |
[Prevalence of methylenetetrahydrofolate reductase (MTHFR) gene polymorphism (C677T) in the Hungarian population].
Topics: Alleles; Europe; Folic Acid; Heterozygote; Homozygote; Humans; Hungary; Hyperhomocysteinemia; International Cooperation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prevalence | 2001 |
Lifestyle factors and plasma homocysteine concentrations in a general population sample.
Topics: Adult; Aged; Alcohol Drinking; Analysis of Variance; Coffee; Cross-Sectional Studies; Diet; Diet Surveys; Exercise; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Linear Models; Male; Middle Aged; Netherlands; Sampling Studies; Smoking; Surveys and Questionnaires; Vitamin B Complex | 2001 |
Power Shortage: clinical trials testing the "homocysteine hypothesis" against a background of folic acid-fortified cereal grain flour.
Topics: Arteriosclerosis; Canada; Clinical Trials as Topic; Data Interpretation, Statistical; Edible Grain; Female; Flour; Folic Acid; Food, Fortified; Health Policy; Humans; Hyperhomocysteinemia; Male; Research Design; United States | 2001 |
Hyperhomocysteinemia in dementia.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Dementia, Vascular; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Mental Status Schedule; Pilot Projects; Reference Values; Regression Analysis; Risk Factors; Vitamin B 12 | 2000 |
Serum cystatin C is an independent predictor of total homocysteine levels in stable Korean renal transplant recipients with normal serum creatinine.
Topics: Adult; Aged; Biomarkers; Creatinine; Cross-Sectional Studies; Cystatin C; Cystatins; Female; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Transplantation; Korea; Male; Middle Aged; Regression Analysis | 2001 |
Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylmalonic Acid; Middle Aged; Prevalence; Surveys and Questionnaires; Vitamin B 12; Vitamin B 12 Deficiency | 2001 |
Mild hyperhomocysteinemia: vitamin supplementation or not?
Topics: Adult; Case-Control Studies; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Methionine; Mutation; Polymorphism, Genetic; Vascular Diseases; Vitamins | 2001 |
[Plasma homocysteine levels in patients with ischemic heart disease].
Topics: Aged; Drug Administration Schedule; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Myocardial Ischemia; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors; Vitamin B 12; Vitamin B 6 | 2001 |
The effect of polymorphisms of MTHER gene and vitamin B on hyperhomocysteinemia.
Topics: Aged; Coronary Artery Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Point Mutation; Polymorphism, Restriction Fragment Length; Vitamin B 12 | 2001 |
Vascular and blood pressure effects of folic acid in older patients with cardiovascular disease.
Topics: Blood Flow Velocity; Blood Pressure; Folic Acid; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Infarction; Oxidoreductases Acting on CH-NH Group Donors; Regression Analysis; Risk Factors; Severity of Illness Index; Stroke | 2001 |
Is hyperhomocysteinemia due to the oxidative depletion of folate rather than to insufficient dietary intake?
Topics: Dementia, Vascular; Diet; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Models, Chemical; Neopterin; Oxidative Stress; Oxygen; Vascular Diseases; Vitamin B 12 | 2001 |
Hyperhomocysteinemia in advanced age.
Topics: Aged; Aging; Chronic Disease; Dietary Supplements; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Time Factors; Vitamin B 6 | 2001 |
Genetic defects as important factors for moderate hyperhomocysteinemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Age Factors; Aged; Aged, 80 and over; Cystathionine; DNA Mutational Analysis; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Protein Binding; Risk Factors; Sex Factors; Vitamin B 12; Vitamin B 6 | 2001 |
Hyperhomocysteinemia is related to residual glomerular filtration and folate, but not to methylenetetrahydrofolate-reductase and methionine synthase polymorphisms, in supplemented end-stage renal disease patients undergoing hemodialysis.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Creatinine; Cystatin C; Cystatins; Female; Folic Acid; Genotype; Glomerular Filtration Rate; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Dialysis; Vitamin B 12 | 2001 |
Elevated homocysteine with weight loss.
Topics: Cardiovascular Diseases; Dietary Supplements; Folic Acid; Gastric Bypass; Humans; Hyperhomocysteinemia; Risk Factors; Vitamin B 12; Weight Loss | 2001 |
Hyperhomocysteinemia and hyperlipidemia in coronary heart disease.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Aged; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases; Point Mutation; Risk Factors; Vitamin B 12 | 1999 |
Antiepileptic drugs as independent predictors of plasma total homocysteine levels.
Topics: Adult; Amino Acid Substitution; Anticonvulsants; Cholesterol; Cholesterol, HDL; Confidence Intervals; Cysteine; Epilepsy; Fasting; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Mutation; Predictive Value of Tests; Prevalence; Statistics, Nonparametric; Threonine; Triglycerides; Vitamin B 12 | 2001 |
Idiopathic osteonecrosis in an adult with familial protein S deficiency and hyperhomocysteinemia.
Topics: Adult; Anticoagulants; Femur Head; Folic Acid; Humans; Hyperhomocysteinemia; Magnetic Resonance Imaging; Male; Osteonecrosis; Paresis; Pedigree; Protein S Deficiency; Radiography; Stroke; Thromboembolism; Thrombophilia; Warfarin | 2001 |
Plasma homocysteine level in relation to folate and vitamin B6 status in apparently normal men.
Topics: Adult; Body Mass Index; Diet, Vegetarian; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Middle Aged; Vitamin B 6; Vitamin B 6 Deficiency | 2001 |
Total homocysteine is making its way into pediatric laboratory diagnostics.
Topics: Adult; Avitaminosis; Child; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; HIV Infections; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylmalonic Acid; Pediatrics; Pregnancy; Vitamin B 12 | 2001 |
Interplay between methylenetetrahydrofolate reductase gene polymorphism 677C-->T and serum folate levels in determining hyperhomocysteinemia in heart transplant recipients.
Topics: Adult; Aged; Coronary Artery Disease; Female; Folic Acid; Genotype; Heart Transplantation; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Function Tests; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Postoperative Complications; Prognosis; Risk Factors | 2001 |
Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia, and cardiovascular diseases in chronic hemodialysis patients.
Topics: Adult; Aged; Cardiovascular Diseases; Cross-Sectional Studies; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidoreductases Acting on CH-NH Group Donors; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renal Dialysis; Risk Factors; Statistics as Topic; Vitamin B 12 | 2002 |
Diet-induced mild hyperhomocysteinemia and increased salt intake diminish vascular endothelial function in a synergistic manner.
Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Carotid Artery, Common; Drug Synergism; Endothelium, Vascular; Folic Acid; Heart Rate; Homocysteine; Hyperhomocysteinemia; Japan; Kidney; Lipid Peroxidation; Lipids; Male; Methionine; Natriuresis; Nitrites; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sodium Chloride, Dietary | 2002 |
Plasma homocysteine levels in Taiwanese vegetarians are higher than those of omnivores.
Topics: Adult; Amino Acids; Cardiovascular Diseases; Diet, Vegetarian; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Middle Aged; Nutritional Status; Regression Analysis; Risk Factors; Taiwan; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency | 2002 |
The Chilean flour folic acid fortification program reduces serum homocysteine levels and masks vitamin B-12 deficiency in elderly people.
Topics: Aged; Cardiovascular Diseases; Chile; Cholesterol, HDL; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Male; Nutritional Status; Prevalence; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Micro- and macrovascular complications and hyperhomocysteinaemia in type 1 diabetic patients.
Topics: Adult; Aging; Blood Pressure; Cholesterol; Cholesterol, HDL; Creatinine; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Retinopathy; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Time Factors | 2001 |
Hyperhomocysteinemia, low folate status, homozygous C677T mutation of the methylene tetrahydrofolate reductase and renal arterial thrombosis.
Topics: Adult; Folic Acid; Homozygote; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Renal Artery Obstruction; Thrombosis | 2002 |
Hyperhomocysteinaemia, folate and vitamin B12 in unsupplemented haemodialysis patients: effect of oral therapy with folic acid and vitamin B12.
Topics: Administration, Oral; Aged; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Genotype; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Renal Dialysis; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Hyperhomocysteinaemia and cardiovascular risk in female ovariectomized rats: role of folic acid and hormone replacement therapy.
Topics: Animals; Cholesterol; Coronary Disease; Estradiol; Female; Folic Acid; Hematinics; Hormone Replacement Therapy; Hyperhomocysteinemia; Nitric Oxide; Ovariectomy; Rats; Rats, Wistar; Risk Factors | 2002 |
Hyperhomocysteinemia and arterial aneurysm.
Topics: Adult; Aneurysm; Angiography; Aspirin; Brachial Artery; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Platelet Aggregation Inhibitors; Popliteal Artery; Treatment Outcome; Ultrasonography, Doppler, Duplex; Vitamin B 6 | 2002 |
Homocysteine gets to the brain.
Topics: Adult; Aged; Alzheimer Disease; Arteriosclerosis; Brain; Cerebral Infarction; Folic Acid; Humans; Hyperhomocysteinemia; Male; Risk Factors; Stroke; Vitamin B 12 | 2002 |
Recurrent stroke in a young patient with celiac disease and hyperhomocysteinemia.
Topics: Adult; Celiac Disease; Coronary Artery Disease; Ferrous Compounds; Folic Acid; Folic Acid Deficiency; Hematinics; Humans; Hyperhomocysteinemia; Male; Recurrence; Stroke | 2002 |
Homocysteine and atheromatous renal artery stenosis.
Topics: Aged; Alleles; Arteriosclerosis; Case-Control Studies; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Artery Obstruction; Risk Factors; Vitamin B 12 | 2001 |
Age, sex and vitamin status affect plasma level of homocysteine, but hyperhomocysteinaemia is possibly not an important risk factor for venous thrombophilia in Taiwanese Chinese.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Case-Control Studies; China; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nutritional Status; Odds Ratio; Risk Factors; Sex Factors; Taiwan; Thrombophilia; Vitamin B 12 | 2002 |
B vitamins and restenosis after coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Coronary Restenosis; Folic Acid; Humans; Hyperhomocysteinemia; Stents; United States; Vitamin B Complex | 2002 |
Folic acid treatment reduces chemokine release from peripheral blood mononuclear cells in hyperhomocysteinemic subjects.
Topics: Adult; Aged; Case-Control Studies; Chemokine CCL5; Chemokine CXCL1; Chemokine CXCL5; Chemokines; Chemokines, CXC; Chemotactic Factors; Female; Folic Acid; Growth Substances; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Signaling Peptides and Proteins; Interleukin-8; Leukocytes, Mononuclear; Male; Middle Aged | 2002 |
Premature arterial and venous events in three families. Effect of folate levels and MTHFR mutation mediated by family/generation and homocysteine levels.
Topics: Adolescent; Adult; Cardiovascular Diseases; Family Health; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Italy; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Pedigree | 2002 |
Methylenetetrahydrofolate reductase genotype, vitamin B12, and folate influence plasma homocysteine in hemodialysis patients.
Topics: Cross-Sectional Studies; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Renal Dialysis; Vitamin B 12; Vitamin B 12 Deficiency | 2002 |
Hyperhomocyst(e)inemia and MTHFR C677T genotypes in patients with central retinal vein occlusion.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymerase Chain Reaction; Retinal Vein Occlusion; Retrospective Studies; Risk Factors; Vitamin B 12 | 2002 |
Hyperhomocysteinemia evoked by folate depletion: effects on coronary and carotid arterial function.
Topics: Animals; Capillary Permeability; Carotid Arteries; Coronary Vessels; Diet; Elasticity; Folic Acid; Folic Acid Deficiency; Glycation End Products, Advanced; Hyperhomocysteinemia; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vascular Resistance | 2002 |
Effect of vegetarian diet on homocysteine levels.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Luminescent Measurements; Male; Middle Aged; Prevalence; Vitamin B 12 | 2002 |
Recurrent leg ulcers in a young man with hyperhomocysteinemia, factor V Leiden and impaired fibrinolysis.
Topics: Adrenal Cortex Hormones; Adult; Bandages; Chronic Disease; Combined Modality Therapy; Drug Therapy, Combination; Factor V; Fibrinolysis; Fibrinolytic Agents; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Leg Ulcer; Male; Phlebography; Recurrence; Severity of Illness Index; Thrombophilia; Treatment Outcome; Venous Thrombosis | 2002 |
The C677T mutation in the methylenetetrahydrofolate reductase gene contributes to hyperhomocysteinemia in patients taking anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Folic Acid; Folic Acid Deficiency; Genotype; Humans; Hyperhomocysteinemia; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation | 2002 |
Genetic and molecular control of folate-homocysteine metabolism in mutant mice.
Topics: Animals; Blotting, Northern; Disease Models, Animal; Female; Folic Acid; Gene Expression Regulation; Homocysteine; Hyperhomocysteinemia; Liver; Methylmalonic Acid; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Oligonucleotide Array Sequence Analysis; Signal Transduction | 2002 |
Treatment of hyperhomocysteinemia with folic acid: effects on homocysteine levels, coagulation status, and oxidative stress markers.
Topics: Aged; Analysis of Variance; Biomarkers; Blood Coagulation; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Oxidative Stress | 2002 |
Prevalence of hyperhomocysteinemia in an elderly population.
Topics: Age Distribution; Aged; Aged, 80 and over; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Prevalence; Sex Distribution; Vitamin B 12 | 2002 |
The C677T thermolabile variant of methylene tetrahydrofolate reductase on homocysteine, folate and vitamin B12 in a hemodialysis center.
Topics: Adult; Chi-Square Distribution; Female; Folic Acid; Heterozygote; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Renal Dialysis; Statistics, Nonparametric; Vitamin B 12 | 2002 |
Folic acid, Vitamin B(12), and homocysteine in smoking and non-smoking pregnant women.
Topics: Cross-Sectional Studies; Female; Folic Acid; Gestational Age; Homocysteine; Humans; Hyperhomocysteinemia; Nutritional Status; Pregnancy; Pregnancy Complications; Reference Values; Smoking; Vitamin B 12 | 2002 |
Hyperhomocyst(e)inemia, but not methylenetetrahydrofolate reductase C677T mutation, as a risk factor in branch retinal vein occlusion.
Topics: Adult; Aged; Aged, 80 and over; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Retinal Vein Occlusion; Risk Factors; Vitamin B 12 | 2002 |
Hyperhomocysteinemia, MTHFR 677C-->T polymorphism, and stroke.
Topics: Adult; Folic Acid; Food, Fortified; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Predictive Value of Tests; Risk; Sample Size; Sensitivity and Specificity; Stroke | 2002 |
Validation of homocyst(e)ine-lowering treatment in the era of folic acid fortification of cereal grains.
Topics: Clinical Trials as Topic; Edible Grain; Folic Acid; Food, Fortified; Homocystine; Humans; Hyperhomocysteinemia; United States | 2002 |
Hyperhomocysteinemia, and low intakes of folic acid and vitamin B12 in urban North India.
Topics: Adult; Anthropometry; Blood Chemical Analysis; Diet, Vegetarian; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Mental Recall; Obesity; Poverty Areas; Seroepidemiologic Studies; Urban Population; Vitamin B 12 | 2002 |
Homocysteine and C-reactive protein levels in haemodialysis patients.
Topics: Adult; C-Reactive Protein; Case-Control Studies; Coronary Disease; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Vitamin B 12 | 2001 |