Page last updated: 2024-08-17

folic acid and HbS Disease

folic acid has been researched along with HbS Disease in 83 studies

Research

Studies (83)

Timeframe	Studies, this research(%)	All Research%
pre-1990	44 (53.01)	18.7374
1990's	9 (10.84)	18.2507
2000's	12 (14.46)	29.6817
2010's	12 (14.46)	24.3611
2020's	6 (7.23)	2.80

Authors

Authors	Studies
Emodi, IJ; Ezenwosu, OU; Ikefuna, AN; Nnajekwu, CO; Nnajekwu, UC; Onukwuli, VO; Uwaezuoke, NA	1
Chukwu, BF; Emodi, IJ; Ikefuna, AN; Nnajekwu, CO; Nnajekwu, UC; Onukwuli, VO	1
Abd El Hady, NMS; El-Hawwary, AM; Mahmoud, AA; Rizk, MS; Saleh, NY	1
Attalla, S; Azzam, M	1
Aleluia, MM; Carvalho, SP; da Guarda, CC; Fernandes, CFL; Figueiredo, CVB; Fiuza, LM; Fonseca, CA; Goncalves, MS; Nascimento, VML; Ndidi, US; Neres, JSDS; Oliveira, RM; Rocha, LC; Santiago, RP; Yahouédéhou, SCMA	1
Chen, PC; Cheung, AT; Green, R; Lin, X; Miller, JW; Samarron, SL; Wun, T; Zwerdling, T	1
Adams, E; Devlin, AM; Karakochuk, CD; McCartney, H; Singer, J; Vercauteren, S; Williams, BA; Wu, JK	1
Abas, AB; Dixit, R; Madan, SS; Nettem, S; Soe, HHK; Stover, PJ; Vance, LD	1
Anderson, BL; Azonobi, IC; Byams, VR; Grant, AM; Schulkin, J	1
Abas, AB; Dixit, R; Madan, SS; Nettem, S; Soe, HH; Stover, PJ; Vance, LD	1
Brito, LC; Ferreira, SB; Martelli, H; Ribeiro, AP; Rosa, MA; Tavares, WL; Vieira, LQ	1
Habib, AG; Kuznik, A; Lamorde, M; Munube, D	1
Dulman, RY; Goldener, C; Lewis, A; Nguyen, GT; Reed, B; Yang, E	1
Alves de Almeida, E; Belini Junior, E; Bonini-Domingos, CR; da Silva, DGH; de Souza Torres, L; Garcia de Oliveira, R; Lopes de Castro Lobo, C; Marcel Barberino, W; Okumura, JV; Urbinatti Teixeira, V	1
Adam, AM; Maritim, MC	1
Bellevue, R; Carmel, R; Kelman, Z	1
DeBaun, MR; Lindsey, T; Patel, NG; Strunk, RC	1
Arlet, JB; Pouchot, J; Ribeil, JA	1
Guru, KN; Moghe, S; Nair, PP; Pillai, A	1
Bellevue, R; Carmel, R; Dhar, M	1
Hoffer, LJ	1
WATSON-WILLIAMS, EJ	1
KLIPSTEIN, FA; LINDENBAUM, J	1
CHARNEY, E; MILLER, G	1
GROSS, S; SHOJANIA, AM	1
HAURANI, FI; TOCANTINS, LM	1
COBB, WT; PEARSON, HA	1
RIEDER, RF; WEATHERALL, DJ	1
PIERCE, LE; RATH, CE	1
Brereton, NH; Miller, ER; Resar, LM; Segal, JB	1
Bellevue, R; Brar, S; Carmel, R; Dhar, M	1
Ballas, SK; Baxter, JK; Riddick, G	1
Adjaoud, D	1
Cueto González, AM; Díaz Conradi, A; Fábrega Sabaté, J; Mate García, MA; Solé Heuberger, E; Tobeña Boada, L; Villalba Hernández, T	1
GAVOSTO, F; PAOLINO, W	1
STEARNER, SP	1
Alperin, JB	1
Burka, ER; Marks, PA	1
Alavi, JB	1
Grandison, Y; Hayes, RJ; Mason, K; Rabb, LM; Serjeant, B; Serjeant, GR	1
Akinkugbe, FM; Ette, SI	1
Serjeant, BE; Serjeant, GR	1
Ballas, SK; Saidi, P	1
Castro, OL; Houston, PE; Kim, KS; Perlin, E; Rana, S; Sekhsaria, S	1
Bakker, AJ; Brouwer, DA; Duits, AJ; Muskiet, FA; Muskiet, FD; Schnog, JJ; van den Berg, GA; van der Dijs, FP; Velvis, HJ	1
Ballas, SK	2
de Seixas, MA; Franchin Júnior, CA; Leal, SM; Ortiz, J; Silva, CE	1
Fokkema, MR; Muskiet, FA; Muskiet, FD; van der Dijs, FP	1
Harkness, J; Hebbel, RP; Solovey, AA; Solovey, AN	1
Fokkema, MR; Muskiet, FA; Muskiet, FD; Schnog, JB; van der Dijs, FP	1
Dijck-Brouwer, DA; Duits, AJ; Fokkema, MR; Muskiet, FA; Muskiet, FD; Niessink, B; Schnog, JJ; van der Dijs, FP; van der Wal, TI	1
Lehmann, H	1
Perkins, RP	1
Liu, YK	2
Westerman, MP	1
Endeley, EM; Enwerem, EO; Holcombe, C; Patel, RV	1
Bartlett, JM; Gray, NT; Holbrook, CT; Horner, RD; Kolasa, KM; Marcuard, SP	1
Davis, RE	1
Orringer, EP; Redding-Lallinger, R; Reed, JD	1
Carmel, R; Johnson, CS; Karnaze, DS; Siegel, ME; Sinow, RM	1
Serjeant, GR	1
Gilles, HM; Lesi, F; Odutola, A; Ransome-Kuti, O; Ransome-Kuti, S; Reid, HA	1
Huntsman, RG; Lehmann, H	1
Woodruff, AW	1
Desforges, J	1
Scott, DE	1
Mann, JR; Stuart, J	1
Charache, S	1
Cooperman, JM; Lopez, R; Shimizu, N	1
Cowan, DH; Harris, JW; Haut, MJ	1
Harrison, KA; Ibeziako, PA	1
Bellina, JH; Bickers, JN	1
Desai, P; Grantham-McGregor, SM; Milner, PF	1
Freedman, ML	1
Ozsoylu, S	1
Barnes, PM; Hendrickse, RG	1
Crosby, WM; Marshall, RA	1
Pritchard, JA; Scott, DE; Whalley, PJ	1
Seymour, A	1
Beutler, E; Opalinski, A	1
Gautier, G; Leikin, S; Purugganan, G	1

Reviews

14 review(s) available for folic acid and HbS Disease

Article	Year
Folate supplementation in people with sickle cell disease. The Cochrane database of systematic reviews, 2018, 03-16, Volume: 3 Topics: Anemia, Sickle Cell; Child, Preschool; Double-Blind Method; Erythrocyte Indices; Folic Acid; Growth; Hematinics; Humans; Infant	2018
Folate supplementation in people with sickle cell disease. The Cochrane database of systematic reviews, 2016, Feb-16, Volume: 2 Topics: Anemia, Sickle Cell; Child; Erythrocyte Indices; Folic Acid; Growth; Hematinics; Humans	2016
CERTAIN ENVIRONMENTAL CONDITIONS AND HEMATOLOGICAL DISORDERS. Archives of environmental health, 1964, Volume: 8 Topics: Altitude; Anemia; Anemia, Macrocytic; Anemia, Sickle Cell; Ascorbic Acid; Celiac Disease; Climate; Deficiency Diseases; Female; Folic Acid; Hematology; Humans; Infant; Metabolism; Nutrition Disorders; Parasitic Diseases; Pharmaceutical Preparations; Poisons; Polycythemia; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Radiation Effects; Seasons; Sprue, Tropical; Vitamin B 12	1964
Sickle cell anemia. Pathophysiology and treatment. The Medical clinics of North America, 1984, Volume: 68, Issue:3 Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Azepines; Blood Transfusion; Cerebrovascular Disorders; Child; Child, Preschool; Female; Folic Acid; Humans; Male; Phenothiazines; Pneumococcal Infections; Pregnancy; Pregnancy Complications, Hematologic; Priapism; Urea; Vaccination	1984
Management of sickle cell disease; lessons from the Jamaican Cohort Study. Blood reviews, 1993, Volume: 7, Issue:3 Topics: Adolescent; Anemia, Aplastic; Anemia, Sickle Cell; Cause of Death; Cerebrovascular Disorders; Child; Cholelithiasis; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Growth Disorders; Humans; Incidence; Infections; Jamaica; Male; Parvoviridae Infections; Prospective Studies; Retinal Diseases; Splenic Diseases; Survival Rate; Thoracic Diseases; Treatment Outcome	1993
Complications of sickle cell anemia in adults: guidelines for effective management. Cleveland Clinic journal of medicine, 1999, Volume: 66, Issue:1 Topics: Adult; Analgesics, Opioid; Anemia, Sickle Cell; Brain Diseases; Chest Pain; Child; Child, Preschool; Chronic Disease; Digestive System Diseases; Female; Female Urogenital Diseases; Folic Acid; Heart Diseases; Hematologic Diseases; Humans; Hydroxyurea; Male; Male Urogenital Diseases; Pain; Pain Management; Practice Guidelines as Topic; Retinal Diseases; Transfusion Reaction	1999
Sickle cell disease: clinical management. Bailliere's clinical haematology, 1998, Volume: 11, Issue:1 Topics: Adult; Anemia, Sickle Cell; Blood Transfusion; Bone Marrow Transplantation; Cardiovascular Diseases; Folic Acid; Humans; Infections; Nervous System Diseases; Pain Management; Respiratory Insufficiency	1998
Clinical chemistry of folic acid. Advances in clinical chemistry, 1986, Volume: 25 Topics: Absorption; Aged; Alcoholism; Anemia, Sickle Cell; Anticonvulsants; Arthritis, Rheumatoid; Biological Assay; Biological Transport; Bone Marrow; Carrier Proteins; Chemical Phenomena; Chemistry; Contraceptives, Oral; Female; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Food Analysis; Formiminoglutamic Acid; Glutamate Formimidoyltransferase; Humans; Hydroxymethyl and Formyl Transferases; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infections; Kidney Failure, Chronic; Malabsorption Syndromes; Malaria; Methotrexate; Neoplasms; Nervous System Diseases; Nutritional Requirements; Parenteral Nutrition, Total; Pregnancy; Pyrimethamine; Receptors, Cell Surface; Terminology as Topic; Thalassemia; Transferases; Trimethoprim	1986
Nutrition and sickle cell disease. American journal of hematology, 1987, Volume: 24, Issue:4 Topics: Anemia, Sickle Cell; Avitaminosis; Folic Acid; Food; Humans; Minerals; Nutritional Status; Pyridoxine; Sickle Cell Trait; Vitamin B 6 Deficiency; Vitamin E Deficiency; Vitamins; Zinc	1987
Recent work on anaemias in the tropics. British medical bulletin, 1972, Volume: 28, Issue:1 Topics: Anemia; Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Sickle Cell; Child; Child, Preschool; Feces; Female; Fever; Folic Acid; Hemoglobinopathies; Hookworm Infections; Humans; Infant; Leishmaniasis, Visceral; Malaria; Male; Pregnancy; Protozoan Infections; Schistosomiasis; Vitamin B 12	1972
Anemia complicating pregnancy. The Journal of reproductive medicine, 1973, Volume: 10, Issue:3 Topics: Anemia; Anemia, Hemolytic, Congenital; Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Sickle Cell; Blood Transfusion; Female; Folic Acid; Folic Acid Deficiency; Genetic Counseling; Humans; Iron; Pregnancy; Pregnancy Complications, Hematologic; Prenatal Diagnosis; Thalassemia	1973
Anemia in pregnancy. Obstetrics and gynecology annual, 1972, Volume: 1 Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Sickle Cell; Blood Coagulation; Blood Transfusion; Blood Volume; Diet; Female; Folic Acid; Hemoglobin C Disease; Hemoglobins; Humans; Iron; Leukocyte Count; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Complications, Hematologic; Pregnancy Complications, Infectious; Thalassemia	1972
The treatment of sickle cell anemia. Archives of internal medicine, 1974, Volume: 133, Issue:4 Topics: Abortion, Therapeutic; Adolescent; Anemia, Sickle Cell; Anesthesia; Bacterial Infections; Bloodletting; Child; Diagnosis, Differential; Exchange Transfusion, Whole Blood; Female; Folic Acid; Humans; Informed Consent; Osteomyelitis; Pregnancy; Pregnancy Complications, Hematologic; Pyelonephritis; Quality of Health Care; Salmonella Infections	1974
Treatment of crises in sickle cell anemia. The American journal of the medical sciences, 1971, Volume: 261, Issue:6 Topics: Acid-Base Equilibrium; Anemia, Sickle Cell; Blood Transfusion; Carrier State; Erythrocytes, Abnormal; Eugenics; Folic Acid; Hemoglobins, Abnormal; Humans; Physician-Patient Relations; Urea	1971

Trials

7 trial(s) available for folic acid and HbS Disease

Article	Year
Folic acid supplementation in children with sickle cell disease: study protocol for a double-blind randomized cross-over trial. Trials, 2020, Jun-29, Volume: 21, Issue:1 Topics: Anemia, Sickle Cell; Canada; Child; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Erythrocyte Indices; Folic Acid; Growth; Hematinics; Humans; Nutritional Status; Randomized Controlled Trials as Topic	2020
A trial of folate supplementation in children with homozygous sickle cell disease. British journal of haematology, 1983, Volume: 54, Issue:4 Topics: Anemia, Sickle Cell; Body Height; Body Weight; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Folic Acid; Humans; Infant	1983
Ascorbic acid in sickle cell disease: results of a pilot therapeutic trial. East African medical journal, 1983, Volume: 60, Issue:10 Topics: Anemia, Sickle Cell; Ascorbic Acid; Child; Child, Preschool; Drug Therapy, Combination; Folic Acid; Humans; Infant; Pilot Projects	1983
Elevated homocysteine levels indicate suboptimal folate status in pediatric sickle cell patients. American journal of hematology, 1998, Volume: 59, Issue:3 Topics: Adolescent; Anemia, Sickle Cell; Child; Child, Preschool; Dietary Supplements; Female; Folic Acid; Hemoglobin SC Disease; Homocysteine; Humans; Infant; Male; Pyridoxine; Vitamin B 12	1998
Treatment of sickle cell disease in early childhood in Jamaica. The American journal of pediatric hematology/oncology, 1985,Fall, Volume: 7, Issue:3 Topics: Acute Disease; Anemia, Sickle Cell; Bacterial Vaccines; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Folic Acid; Food, Fortified; Haemophilus influenzae; Hemoglobins; Humans; Infant; Jamaica; Mass Screening; Penicillins; Pneumococcal Infections; Prospective Studies; Random Allocation; Retinal Diseases; Splenectomy; Splenic Diseases	1985
Sodium bicarbonate prophylaxis of sickle cell crisis. Pediatrics, 1974, Volume: 53, Issue:3 Topics: Administration, Oral; Adolescent; Anemia, Sickle Cell; Bicarbonates; Child; Child, Preschool; Clinical Trials as Topic; Female; Folic Acid; Humans; Hydrogen-Ion Concentration; Male; Sodium; Time Factors	1974
Sickle cell anaemia: report of a therapeutic trial. The West African medical journal, 1966, Volume: 15, Issue:2 Topics: Anemia, Sickle Cell; Antimalarials; Child; Child, Preschool; Clinical Trials as Topic; Female; Folic Acid; Humans; Male; Steroids; Sulfonamides; Vitamin B 12; Vitamin D	1966

Other Studies

62 other study(ies) available for folic acid and HbS Disease

Article	Year
Relationship between disease severity and folate status of children with sickle cell anaemia in Enugu, South East Nigeria. African health sciences, 2021, Volume: 21, Issue:2 Topics: Adolescent; Anemia, Sickle Cell; Child; Child, Preschool; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Male; Nigeria; Severity of Illness Index	2021
Folate levels in children with sickle cell anaemia on folic acid supplementation in steady state and crises at a tertiary hospital in Enugu, Nigeria: a prospective, comparative study. Malawi medical journal : the journal of Medical Association of Malawi, 2022, Volume: 34, Issue:2 Topics: Anemia, Sickle Cell; Child; Dietary Supplements; Folic Acid; Humans; Nigeria; Prospective Studies; Tertiary Care Centers	2022
MTHFR C677T Polymorphism, Plasma Homocysteine, and PDGF-AA Levels and Transcranial Doppler Velocity in Children With Sickle Cell Disease. Indian pediatrics, 2023, 08-15, Volume: 60, Issue:8 Topics: Anemia, Sickle Cell; Child; Folic Acid; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Platelet-Derived Growth Factor	2023
Serum Folate Levels in Patients with Chronic Hemolytic Anemia on Regular Folic Acid Supplementation Before and After Dose Modification. Indian pediatrics, 2019, 10-15, Volume: 56, Issue:10 Topics: Anemia, Hemolytic; Anemia, Sickle Cell; beta-Thalassemia; Child; Chronic Disease; Cross-Sectional Studies; Dietary Supplements; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Folic Acid; Humans; Male; Prognosis; Risk Assessment; Saudi Arabia; Statistics, Nonparametric; Treatment Outcome	2019
Sickle cell disease: A distinction of two most frequent genotypes (HbSS and HbSC). PloS one, 2020, Volume: 15, Issue:1 Topics: Adolescent; Anemia, Sickle Cell; Biomarkers; Child; Cross-Sectional Studies; Female; Folic Acid; Genotype; Hemoglobin SC Disease; Hemoglobin, Sickle; Humans; Hydroxyurea; Male	2020
Homocysteine is associated with severity of microvasculopathy in sickle cell disease patients. British journal of haematology, 2020, Volume: 190, Issue:3 Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Creatine; Folic Acid; Homocysteine; Humans; Intravital Microscopy; Microcirculation; Middle Aged; Pyridoxal Phosphate; Severity of Illness Index; Thrombotic Microangiopathies; Vitamin B 12	2020
Obstetrician-gynecologists' knowledge of sickle cell disease screening and management. BMC pregnancy and childbirth, 2014, Oct-14, Volume: 14 Topics: Africa; Anemia, Sickle Cell; Asia; Clinical Competence; Education, Medical; Fellowships and Scholarships; Female; Folic Acid; Gynecology; Humans; Male; Mass Screening; Mediterranean Region; Middle Aged; Obstetrics; Pregnancy; Pregnancy Complications, Hematologic; Sickle Cell Trait; Vitamin B Complex	2014
Sickle cell anemia in Brazil: personal, medical and endodontic patterns. Brazilian oral research, 2016, May-20, Volume: 30, Issue:1 Topics: Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Transfusion; Brazil; Child; Child, Preschool; Cross-Sectional Studies; Dental Pulp Diseases; Female; Folic Acid; Humans; Hydroxyurea; Leukocyte Count; Male; Middle Aged; Needs Assessment; Root Canal Therapy; Serologic Tests; Splenectomy; Vitamin B Complex; Young Adult	2016
Newborn screening and prophylactic interventions for sickle cell disease in 47 countries in sub-Saharan Africa: a cost-effectiveness analysis. BMC health services research, 2016, 07-26, Volume: 16 Topics: Adolescent; Africa South of the Sahara; Anemia, Sickle Cell; Antimalarials; Child; Child, Preschool; Cost-Benefit Analysis; Folic Acid; Humans; Incidence; Infant; Infant, Newborn; Life Expectancy; Malaria; Neonatal Screening; Quality-Adjusted Life Years; Retrospective Studies	2016
Discontinuation of Folic Acid Supplementation in Young Patients With Sickle Cell Anemia. Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:6 Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Dietary Supplements; Female; Folic Acid; Hemoglobins; Humans; Hydroxyurea; Infant; Male; Reticulocyte Count; Withholding Treatment; Young Adult	2017
Impact of genetic polymorphisms in key enzymes of homocysteine metabolism on the pathophysiology of sickle cell anemia. Free radical biology & medicine, 2017, Volume: 106 Topics: Adolescent; Adult; Alleles; Anemia, Sickle Cell; Child; Cystathionine beta-Synthase; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidative Stress; Polymorphism, Genetic; Young Adult	2017
Pseudoxanthoma elasticum in a patient with sickle cell disease: case report. East African medical journal, 2008, Volume: 85, Issue:2 Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anemia, Sickle Cell; Anti-Bacterial Agents; Ceftriaxone; Epistaxis; Female; Folic Acid; Humans; Pseudoxanthoma Elasticum; Vitamin B Complex	2008
Low cobalamin levels associated with sickle cell disease: Contrasting origins and clinical meanings in two instructive patients. American journal of hematology, 2010, Volume: 85, Issue:6 Topics: Adult; Anemia, Pernicious; Anemia, Sickle Cell; Autoantibodies; Depression; Female; Folic Acid; Gastrins; Hemoglobin SC Disease; Humans; Hydroxyurea; Hyperhomocysteinemia; Intrinsic Factor; Iron Overload; Male; Methylmalonic Acid; Pneumonia; Transcobalamins; Transfusion Reaction; Treatment Refusal; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult	2010
Prevalence of daily medication adherence among children with sickle cell disease: a 1-year retrospective cohort analysis. Pediatric blood & cancer, 2010, Volume: 55, Issue:3 Topics: Anemia, Sickle Cell; Anti-Asthmatic Agents; Antisickling Agents; Child; Cohort Studies; Folic Acid; Hematinics; Humans; Hydroxyurea; Medication Adherence; Penicillins	2010
[Abnormal tongue]. La Revue de medecine interne, 2012, Volume: 33, Issue:4 Topics: Adult; Anemia, Sickle Cell; Diagnosis, Differential; Female; Folic Acid; Glossitis, Benign Migratory; Humans; Treatment Outcome; Vitamin B Complex	2012
Idiopathic facial swelling secondary to sickle cell anaemia. BMJ case reports, 2012, Oct-10, Volume: 2012 Topics: Adult; Anemia, Sickle Cell; Anti-Bacterial Agents; Bacterial Infections; Edema; Face; Folic Acid; Hematinics; Humans; Male; Young Adult	2012
Pernicious anemia with neuropsychiatric dysfunction in a patient with sickle cell anemia treated with folate supplementation. The New England journal of medicine, 2003, May-29, Volume: 348, Issue:22 Topics: Adult; Anemia, Pernicious; Anemia, Sickle Cell; Cognition Disorders; Female; Folic Acid; Humans; Mental Disorders; Neuropsychological Tests; Vitamin B 12	2003
Folate supplementation in sickle cell anemia. The New England journal of medicine, 2003, Aug-21, Volume: 349, Issue:8 Topics: Anemia, Sickle Cell; Female; Folic Acid; Humans; Vitamin B 12	2003
Folic acid deficiency in sickle-cell anaemia. East African medical journal, 1962, Volume: 39 Topics: Anemia; Anemia, Sickle Cell; Folic Acid; Folic Acid Deficiency; Humans	1962
FOLIC ACID DEFICIENCY IN SICKLE-CELL ANEMIA. The New England journal of medicine, 1963, Oct-24, Volume: 269 Topics: Anemia; Anemia, Sickle Cell; Avitaminosis; Erythropoiesis; Folic Acid; Folic Acid Deficiency; Humans; Vitamin B 12; Vitamin B Deficiency	1963
RETICULOCYTOPENIA IN SICKLE CELL DISEASE. APLASTIC EPISODES IN THE COURSE OF SICKLE CELL DISEASE IN CHILDREN. American journal of diseases of children (1960), 1964, Volume: 107 Topics: Anemia; Anemia, Sickle Cell; Ascorbic Acid; Child; Erythrocytes, Abnormal; Erythropoiesis; Folic Acid; Humans; Infections; Pathology; Reticulocytes	1964
HEMOLYTIC ANEMIAS AND FOLIC ACID DEFICIENCY IN CHILDREN. American journal of diseases of children (1960), 1964, Volume: 108 Topics: Adolescent; Anemia; Anemia, Hemolytic; Anemia, Sickle Cell; Black People; Blood; Child; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Infant; Urine; Vitamin B Deficiency	1964
FOLIC ACID STUDIES IN SICKLE-CELL ANEMIA. The Journal of laboratory and clinical medicine, 1964, Volume: 64 Topics: Anemia; Anemia, Sickle Cell; Blood Chemical Analysis; FIGLU Test; Folic Acid; Folic Acid Deficiency; Hemoglobinometry; Histidine; Humans; Metabolism; Urine	1964
STUDIES ON HEMOGLOBIN BIOSYNTHESIS: ASYNCHRONOUS SYNTHESIS OF HEMOGLOBIN A AND HEMOGLOBIN A2 BY ERYTHROCYTE PRECURSORS. The Journal of clinical investigation, 1965, Volume: 44 Topics: Anemia; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Pernicious; Anemia, Sickle Cell; Blood Protein Electrophoresis; Bone Marrow; Chromatography; Folic Acid; Folic Acid Deficiency; Hemoglobin A2; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Iron; Iron Isotopes; Leucine; Metabolic Diseases; Primary Myelofibrosis; Proteins; Pyruvate Kinase; Reticulocytes; Spherocytosis, Hereditary; Thalassemia; Vitamin B Deficiency	1965
Evidence for folic acid deficiency in the genesis of anemic sickle cell crisis. Blood, 1962, Volume: 20 Topics: Anemia; Anemia, Sickle Cell; Erythrocytes, Abnormal; Folic Acid; Folic Acid Deficiency; Humans	1962
Concentrations of B vitamins and homocysteine in children with sickle cell anemia. Southern medical journal, 2004, Volume: 97, Issue:2 Topics: Anemia, Sickle Cell; Black People; Case-Control Studies; Child; Diet; Female; Folic Acid; Homocysteine; Humans; Male; Vitamin B 6; Vitamins	2004
Mild hyperhomocysteinemia in adult patients with sickle cell disease: a common finding unrelated to folate and cobalamin status. American journal of hematology, 2004, Volume: 76, Issue:2 Topics: Adult; Aged; Anemia, Sickle Cell; Creatinine; Female; Folic Acid; Hemoglobin SC Disease; Humans; Hyperhomocysteinemia; Male; Middle Aged; Regression Analysis; Reproducibility of Results; Vitamin B 12	2004
Folate supplementation and twinning in patients with sickle cell disease. American journal of hematology, 2006, Volume: 81, Issue:4 Topics: Abortion, Spontaneous; Adolescent; Adult; Anemia, Sickle Cell; Erythropoiesis; Female; Fetal Death; Folic Acid; Hematinics; Humans; Parity; Pregnancy; Twinning, Monozygotic; Vitamin B 12 Deficiency	2006
[Physiopathology and treatment of sickle cell anemia]. Soins. Pediatrie, puericulture, 2007, Issue:234 Topics: Analgesics; Anemia, Sickle Cell; Blood Transfusion; Bone Marrow Transplantation; Fluid Therapy; Folic Acid; Genetic Counseling; Genetic Testing; Humans; Hydroxyurea; Infection Control; Pain; Vaccination	2007
[Two splenic sequestrations in an infant with homozygous sickle cell anemia]. Anales de pediatria (Barcelona, Spain : 2003), 2007, Volume: 66, Issue:3 Topics: Anemia, Sickle Cell; Antisickling Agents; Folic Acid; Homozygote; Humans; Hydroxyurea; Infant; Male; Splenic Diseases	2007
Folic acid effect in two cases of microcytic, hypochromic, agastric anemia with deficiency syndrome. Minerva medica, 1948, Oct-27, Volume: 39, Issue:43 Pt 2 Topics: Anemia; Anemia, Sickle Cell; Folic Acid; Humans	1948
Effects of folic acid on the anemia induced by X irradiation. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1948, Volume: 69, Issue:3 Topics: Anemia; Anemia, Sickle Cell; Erythrocytes, Abnormal; Folic Acid; Humans; Tracheophyta	1948
Folic acid deficiency complicating sickle cell anemia. A study on the response to titrated doses of folic acid. Archives of internal medicine, 1967, Volume: 120, Issue:3 Topics: Adolescent; Anemia, Sickle Cell; Bone Marrow; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Iron; L-Lactate Dehydrogenase; Male; Reticulocytes; Vitamin B 12	1967
Protein synthesis in human reticulocytes induced by therapy of megaloblastic anemia. Blood, 1967, Volume: 30, Issue:4 Topics: Adult; Aged; Anemia, Macrocytic; Anemia, Pernicious; Anemia, Sickle Cell; Blood Proteins; Carbon Isotopes; Female; Folic Acid; Humans; In Vitro Techniques; Male; Middle Aged; Reticulocytes; Ribosomes; Schilling Test; Vitamin B 12	1967
Thrombosis, megaloblastic anaemia, and sickle cell disease: a unified hypothesis. British journal of haematology, 1997, Volume: 96, Issue:4 Topics: Anemia, Megaloblastic; Anemia, Sickle Cell; Folic Acid; Humans; Thrombosis	1997
Homocysteine in sickle cell disease: relationship to stroke. The American journal of medicine, 1997, Volume: 103, Issue:3 Topics: Adolescent; Adult; Anemia, Sickle Cell; Cerebrovascular Disorders; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Infant; Logistic Models; Male; Middle Aged; Odds Ratio; Severity of Illness Index	1997
Myocardial bridge in a patient with sickle cell anemia. Arquivos brasileiros de cardiologia, 1999, Volume: 72, Issue:2 Topics: Adult; Anemia, Sickle Cell; Ascorbic Acid; Coronary Vessel Anomalies; Female; Folic Acid; Free Radical Scavengers; Hematinics; Humans; Pentoxifylline	1999
Erythrocyte folate does not accurately reflect folate status in sickle cell disease. Clinical chemistry, 2000, Volume: 46, Issue:12 Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Erythrocytes; Folic Acid; Humans; Infant; Infant, Newborn	2000
Modulation of endothelial cell activation in sickle cell disease: a pilot study. Blood, 2001, Apr-01, Volume: 97, Issue:7 Topics: Adult; Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation; E-Selectin; Endothelium, Vascular; Feasibility Studies; Female; Folic Acid; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pilot Projects; Safety; Salicylates; Sulfasalazine; Thromboplastin; Transcription, Genetic; Vascular Cell Adhesion Molecule-1	2001
Folate status assessment and folic acid supplements in sickle cell disease. Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:8 Topics: Anemia, Sickle Cell; Dietary Supplements; Erythrocytes; Folic Acid; Homocysteine; Humans; Nutritional Status	2001
Optimization of folic acid, vitamin B(12), and vitamin B(6) supplements in pediatric patients with sickle cell disease. American journal of hematology, 2002, Volume: 69, Issue:4 Topics: Adolescent; Anemia, Sickle Cell; Child; Dietary Supplements; Erythrocytes; Female; Folic Acid; Hemoglobin SC Disease; Homocysteine; Humans; Male; Nutrition Policy; Vitamin B 12; Vitamin B 6	2002
The therapy of sickle-cell anemia. Progress in clinical and biological research, 1979, Volume: 34 Topics: Anemia, Sickle Cell; Antisickling Agents; Blood Transfusion; Folic Acid; Humans; Mutation	1979
Partial exchange transfusion in a pregnant patient with sickle cell anemia. Obstetrics and gynecology, 1976, Volume: 48, Issue:1 Suppl Topics: Anemia, Sickle Cell; Exchange Transfusion, Whole Blood; Female; Folic Acid; Heart Failure; Hematuria; Hemoglobin, Sickle; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Hematologic	1976
Folic acid deficiency in sickle cell anaemia. Scandinavian journal of haematology, 1975, Volume: 14, Issue:1 Topics: Adolescent; Adult; Aged; Anemia, Sickle Cell; Blood Cell Count; Child; Child, Preschool; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Hematocrit; Humans; Infant; Male; Middle Aged; Neutrophils; Reticulocytes	1975
Hypocholesterolaemia and anaemia. British journal of haematology, 1975, Volume: 31, Issue:1 Topics: Anemia; Anemia, Aplastic; Anemia, Megaloblastic; Anemia, Sickle Cell; Blood Transfusion; Cholesterol; Erythrocyte Aging; Erythrocytes; Folic Acid; Hematocrit; Humans; Liver Cirrhosis; Osmotic Fragility; Spherocytosis, Hereditary; Splenectomy; Vitamin B 12	1975
Priapism in children with sickle-cell disease. Indian pediatrics, 1992, Volume: 29, Issue:8 Topics: Anemia, Sickle Cell; Antimalarials; Ascorbic Acid; Blood Chemical Analysis; Child; Folic Acid; Humans; Injections, Intravenous; Lactates; Male; Penile Erection; Priapism; Vitamin B Complex	1992
Nutritional status and dietary intake of children with sickle cell anemia. The American journal of pediatric hematology/oncology, 1992,Spring, Volume: 14, Issue:1 Topics: Anemia, Sickle Cell; Child; Diet Records; Energy Metabolism; Female; Folic Acid; Humans; Iron; Male; Nutritional Status; Vitamin A; Zinc	1992
Unsuspected pernicious anemia in a patient with sickle cell disease receiving routine folate supplementation. Archives of internal medicine, 1987, Volume: 147, Issue:10 Topics: Adult; Anemia, Pernicious; Anemia, Sickle Cell; Female; Folic Acid; Humans; Vitamin B 12	1987
Arvin treatment for sickle-cell crisis. Lancet (London, England), 1968, Sep-07, Volume: 2, Issue:7567 Topics: Adolescent; Anemia, Sickle Cell; Anticoagulants; Blood Coagulation Tests; Child; Child, Preschool; Female; Fibrinogen; Folic Acid; Hematuria; Humans; Infant; Male; Pyrimethamine	1968
Treatment of sickle-cell disease. British journal of haematology, 1974, Volume: 28, Issue:4 Topics: Anemia, Sickle Cell; Anesthesia; Anticoagulants; Aspirin; Bicarbonates; Blood; Blood Flow Velocity; Blood Viscosity; Body Temperature; Bone Marrow Cells; Cyanates; Female; Folic Acid; Hemoglobin, Sickle; Hemolysis; Humans; Hydrogen-Ion Concentration; Hygiene; Infarction; Kidney Concentrating Ability; Leg Ulcer; Male; Maternal Mortality; Models, Structural; Pregnancy; Pregnancy Complications, Hematologic; Thrombophlebitis; Urea	1974
Recurrent folic acid deficiency in sickle cell disease. American journal of diseases of children (1960), 1973, Volume: 125, Issue:4 Topics: Anemia, Macrocytic; Anemia, Sickle Cell; Child; FIGLU Test; Folic Acid; Folic Acid Deficiency; Growth Disorders; Hemoglobinometry; Histidine; Humans; Intestinal Absorption; Male; Recurrence; Vitamin B 12	1973
Platelet function and survival in sickle cell disease. The Journal of laboratory and clinical medicine, 1973, Volume: 82, Issue:1 Topics: Adenosine Diphosphate; Adult; Anemia, Sickle Cell; Bilirubin; Blood Cell Count; Blood Platelets; Cell Survival; Chromium Isotopes; Collagen; Epinephrine; Erythrocyte Count; Erythrocytes; Folic Acid; Hematocrit; Hemoglobins; Humans; In Vitro Techniques; Isotope Labeling; L-Lactate Dehydrogenase; Leukocyte Count; Platelet Adhesiveness; Thrombin	1973
Maternal anaemia and fetal birthweight. The Journal of obstetrics and gynaecology of the British Commonwealth, 1973, Volume: 80, Issue:9 Topics: Anemia; Anemia, Sickle Cell; Birth Weight; Blood Transfusion; Body Height; Chloroquine; Embryonic and Fetal Development; Female; Fetal Death; Folic Acid; Folic Acid Deficiency; Gestational Age; Hematocrit; Hemoglobinopathies; Humans; Malaria; Pregnancy; Pregnancy Complications; Pyrimethamine; Socioeconomic Factors	1973
Folate deficiency in children with sickle cell anemia. American journal of diseases of children (1960), 1974, Volume: 127, Issue:3 Topics: Anemia, Sickle Cell; Body Height; Body Weight; Child; Child, Preschool; Diet; Erythrocytes; Folic Acid; Folic Acid Deficiency; Growth Disorders; Hematocrit; Hemoglobinometry; Hemoglobinopathies; Humans; Income; Infant	1974
Modern management of sickle cell disease in pregnancy. Southern medical journal, 1974, Volume: 67, Issue:4 Topics: Abortion, Spontaneous; Anemia, Sickle Cell; Black or African American; Blood Transfusion; Blood Viscosity; Blood Volume Determination; Catheterization; Chlorpromazine; Exchange Transfusion, Whole Blood; Female; Folic Acid; Heart Failure; Hemoglobinometry; Heparin; Humans; Meperidine; Obstetric Labor, Premature; Oxygen; Partial Pressure; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Prognosis; Rheology; Serum Albumin, Radio-Iodinated; Veins	1974
Haematological levels in Jamaican infants. Archives of disease in childhood, 1974, Volume: 49, Issue:7 Topics: Age Factors; Anemia, Sickle Cell; Birth Weight; Body Weight; Electrophoresis; Female; Folic Acid; Genotype; Hemoglobins; Humans; Infant; Infant, Newborn; Iron; Jamaica; Male; Protein Binding; Sex Factors; Socioeconomic Factors	1974
Homozygous hemoglobin D Punjab. Acta haematologica, 1970, Volume: 43, Issue:6 Topics: Anemia, Sickle Cell; Blood Protein Electrophoresis; Chromatography, DEAE-Cellulose; Erythrocytes; Fetal Hemoglobin; Folic Acid; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Heinz Bodies; Hematocrit; Hemoglobinometry; Hemoglobins, Abnormal; Homozygote; Humans; Iron; Male; Middle Aged; Osmotic Fragility; Pedigree	1970
Anemia in pregnancy. The Journal of the Oklahoma State Medical Association, 1971, Volume: 64, Issue:3 Topics: Anemia; Anemia, Hypochromic; Anemia, Sickle Cell; Anemia, Sideroblastic; Female; Folic Acid; Humans; Iron; Pregnancy; Pregnancy Complications, Hematologic	1971
Maternal folate deficiency and pregnancy wastage. IV. Effects of folic acid supplements, anticonvulsants, and oral contraceptives. American journal of obstetrics and gynecology, 1971, Feb-01, Volume: 109, Issue:3 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anemia, Macrocytic; Anemia, Sickle Cell; Anemia, Sideroblastic; Anticonvulsants; Birth Weight; Contraceptives, Oral; Drug Antagonism; Epilepsy; Female; Fetus; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Hemoglobinometry; Humans; Hypertension; Infant Mortality; Infant, Newborn; Infant, Premature; Iron; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications	1971
Malaria and sickle cell disease. British medical journal, 1971, Jun-19, Volume: 2, Issue:5763 Topics: Anemia, Sickle Cell; Antimalarials; Child; Folic Acid; Genotype; Hemoglobinometry; Humans; Malaria	1971
Creatine, 2,3-diphosphoglycerate and anemia. The New England journal of medicine, 1971, Aug-26, Volume: 285, Issue:9 Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Anemia, Hypochromic; Anemia, Sickle Cell; Anemia, Sideroblastic; Aspartate Aminotransferases; Creatine; Erythrocyte Aging; Erythrocyte Count; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Glycerophosphates; Hematocrit; Hemoglobinuria, Paroxysmal; Hemorrhage; Hexokinase; Humans; Reticulocytes	1971
Folate metabolism in erythroid hyperplastic and hypoplastic states. American journal of diseases of children (1960), 1971, Volume: 122, Issue:1 Topics: Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Sickle Cell; Anemia, Sideroblastic; Blood Cell Count; Blood Platelets; Child; Chronic Disease; Erythrocyte Count; Erythrocytes; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Leukocyte Count; Vitamin B 12	1971