folic acid has been researched along with Genome Instability in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 22 (73.33) | 24.3611 |
| 2020's | 4 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Alnabbat, KI; Bahry, MR; Fardous, AM; Heydari, AR; James, AA; Shahab, A | 1 |
| Wang, J; Wang, X; Yu, J | 1 |
| Bestwick, CS; Catala, GN; Duthie, SJ; Giovannelli, L; Lendoiro, E; Moyer, MP; Russell, WR; Tortora, K | 1 |
| Chabes, A; Hofer, A; Hombauer, H; Kolodziejczak, A; Luke, B; Reyes, GX; Schmidt, TT; Sharma, S; Wagner, T | 1 |
| Arantes, LMRB; Biselli, JM; Carvalho, AL; Carvalho, VM; Eberlin, MN; Goloni-Bertollo, EM; Melendez, ME; Mendes, CC; Pavarino, ÉC; Riccio, MF; Vannucchi, H; Zampieri, BL | 1 |
| Padula, G; Ponzinibbio, MV; Seoane, AI | 1 |
| Behan, NA; LeBlanc, DP; MacFarlane, AJ; Marchetti, F; O'Brien, JM | 1 |
| Cao, N; Dai, X; Guo, X; Ni, J; Wang, X; Xue, J; Yang, G | 1 |
| Abramsson-Zetterberg, L; Bergman, R; Frostne, C; Grawé, J; Haghdoost, S; Jenssen, D; Kotova, N; Paulsson, B; Segerbäck, D; Tareke, E; Törnqvist, M | 1 |
| Fenech, M; Sharif, R; Thomas, P; Zalewski, P | 1 |
| Bester, AC; Im, MM; Karni, R; Kerem, B; Lamm, N; Maoz, K; Shewach, DS | 1 |
| Fenech, M; Hague, W; Owens, J; Singh, MD; Thomas, P | 1 |
| Field, MS; Kamynina, E; Stover, PJ | 1 |
| Alimba, CG; Bakare, AA; Dhillon, V; Fenech, M | 1 |
| Fenech, M; Teo, T | 1 |
| Jacobson, MK; Williams, JD | 1 |
| Cortes, A; El-Zein, RA; Etzel, CJ; Greisinger, AJ; Lopez, MS; Monroy, C; Piskac-Collier, AL; Spitz, MR | 1 |
| Chukoskie, L; Kamen, BA | 1 |
| da Silva, LM; Galbiatti, AL; Goloni-Bertollo, EM; Maniglia, JV; Pavarino, EC; Raposo, LS; Ruiz, MT | 1 |
| Cabelof, DC; Patterson, D | 1 |
| Fenech, M | 1 |
| Lim, U; Song, MA | 1 |
| Anetor, JI | 1 |
| Behan, NA; MacFarlane, AJ; Stover, PJ; Swayne, BG; Williams, A; Yauk, CL | 1 |
| Fenech, M; Lu, L; Ni, J; Wang, X; Xu, W; Zhou, T | 1 |
| Guan, T; Guan, Z; Niu, B; Wang, J; Wang, M; Wang, X; Xiang, Q; Xie, Q; Zhang, T; Zhao, J | 1 |
| Adrigan, S; Brath, H; Bulla, MT; Marek, R; Müllner, E; Stieglmayer, R; Toferer, D; Wagner, KH; Wallner, M | 1 |
| Fenech, M; Higuchi, M; Kimura, M; Thomas, P; Umegaki, K | 1 |
| Fenech, M; Huang, Y; Liang, Z; Wang, X; Wu, X; Xue, J | 1 |
| Chandler, I; Houlston, RS; Hubner, RA; Lubbe, S | 1 |
7 review(s) available for folic acid and Genome Instability
| Article | Year |
|---|---|
Neural Tube Defects and Folate Deficiency: Is DNA Repair Defective?
Topics: DNA; DNA Repair; Folic Acid; Folic Acid Deficiency; Genomic Instability; Humans; Neural Tube Defects | 2023 |
Folate, genomic stability and colon cancer: The use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring.
Topics: Biological Monitoring; Cell Line; Colonic Neoplasms; Comet Assay; DNA Breaks; DNA Methylation; DNA Repair; DNA Replication; Folic Acid; Folic Acid Deficiency; Genomic Instability; Genotype; Homocystinuria; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Risk; Single-Cell Analysis; Uracil | 2019 |
Potential role of folate in pre-eclampsia.
Topics: Dietary Supplements; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Genomic Instability; Humans; Methionine; Oxidative Stress; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Vitamins | 2015 |
Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging.
Topics: Aging; Animals; DNA Polymerase beta; DNA Repair; Down Syndrome; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Genomic Instability; Haploinsufficiency; Humans; Leukemia; MicroRNAs; Oxidative Stress; Phenotype | 2012 |
Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity.
Topics: Animals; Cells, Cultured; Dietary Supplements; DNA Damage; DNA Methylation; Folic Acid; Folic Acid Deficiency; Gene-Environment Interaction; Genome, Mitochondrial; Genomic Instability; Humans; Nutritional Requirements; Vitamin B 12; Vitamin B 12 Deficiency | 2012 |
Dietary and lifestyle factors of DNA methylation.
Topics: Age Factors; Animals; Body Weight; Diet; DNA Methylation; Ethanol; Folic Acid; Genomic Instability; Humans; Life Style; Models, Biological; Motor Activity; Racial Groups; Sex Factors; Smoking | 2012 |
Industrialization and the increasing risk of genome instability in developing countries: nutrigenomics as a promising antidote.
Topics: Antidotes; Developing Countries; DNA Damage; Ecotoxicology; Environmental Pollutants; Folic Acid; Gene Expression; Genetic Markers; Genome, Human; Genomic Instability; Humans; Industry; Micronutrients; Nutrigenomics; Nutrition Policy; Risk; Zinc | 2010 |
3 trial(s) available for folic acid and Genome Instability
| Article | Year |
|---|---|
Zinc supplementation influences genomic stability biomarkers, antioxidant activity, and zinc transporter genes in an elderly Australian population with low zinc status.
Topics: Aged; Aged, 80 and over; Antioxidants; Australia; Biomarkers; Body Mass Index; Carnosine; Cation Transport Proteins; Comet Assay; Dietary Supplements; DNA Damage; Female; Folic Acid; Gene Expression Regulation; Genomic Instability; Healthy Volunteers; Homocysteine; Humans; Male; Metallothionein; Micronutrients; Nutrition Assessment; Superoxide Dismutase; Telomere; Vitamin B 12; Zinc | 2015 |
Genome damage in peripheral blood lymphocytes of diabetic and non-diabetic individuals after intervention with vegetables and plant oil.
Topics: Aged; Anthropometry; beta Carotene; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Carotenoids; Chromosome Aberrations; Diabetes Mellitus, Type 2; DNA Damage; Fatty Acids, Unsaturated; Female; Folic Acid; gamma-Tocopherol; Genome, Human; Genomic Instability; Glycated Hemoglobin; Humans; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Plant Oils; Risk Factors; Vegetables; Vitamin B 12 | 2013 |
A comparison of folic acid deficiency-induced genomic instability in lymphocytes of breast cancer patients and normal non-cancer controls from a Chinese population in Yunnan.
Topics: Adult; Aged; Apoptosis; Breast; Breast Neoplasms; Case-Control Studies; China; Cytokinesis; Female; Folic Acid; Folic Acid Deficiency; Genomic Instability; Humans; Lymphocytes; Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Necrosis; Population Groups | 2006 |
20 other study(ies) available for folic acid and Genome Instability
| Article | Year |
|---|---|
High Dietary Folic Acid Intake Is Associated with Genomic Instability in Peripheral Lymphocytes of Healthy Adults.
Topics: Adult; Dietary Supplements; Folic Acid; Food, Fortified; Genomic Instability; Humans; Lymphocytes; Neural Tube Defects | 2022 |
Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio.
Topics: Cell Nucleus; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; DNA Damage; DNA, Fungal; Folic Acid; Gene Deletion; Gene Expression Regulation, Fungal; Genome, Fungal; Genomic Instability; Mitochondria; Mutation; Peptide Synthases; Saccharomyces cerevisiae; Thymine Nucleotides; Uracil | 2020 |
One-carbon metabolism and global DNA methylation in mothers of individuals with Down syndrome.
Topics: Adolescent; Adult; Aged; Alu Elements; Betaine-Homocysteine S-Methyltransferase; Carbon; DNA Methylation; Down Syndrome; Female; Folic Acid; Genetic Predisposition to Disease; Genome-Wide Association Study; Genomic Instability; Humans; Long Interspersed Nucleotide Elements; Male; Middle Aged; Mother-Child Relations; Mothers; Polymorphism, Genetic; Signal Transduction; Thymidylate Synthase; Transcobalamins; Young Adult | 2021 |
Possible radioprotective effect of folic acid supplementation on low dose ionizing radiation-induced genomic instability in vitro.
Topics: Animals; Apoptosis; CHO Cells; Comet Assay; Cricetulus; DNA Damage; Dose-Response Relationship, Drug; Folic Acid; Genomic Instability; Micronuclei, Chromosome-Defective; Micronucleus Tests; Radiation Dosage; Radiation-Protective Agents | 2016 |
Folate deficiency increases chromosomal damage and mutations in hematopoietic cells in the transgenic mutamouse model.
Topics: Anemia, Megaloblastic; Animals; Dietary Supplements; DNA Damage; Ethylnitrosourea; Female; Folic Acid; Folic Acid Deficiency; Genomic Instability; Hematopoietic Stem Cells; Humans; Lac Operon; Male; Mice; Mice, Transgenic; Mutagenesis; Mutagens; Mutation; Neural Tube Defects | 2018 |
High concentration of sugars is genotoxic to folate-deficient cells.
Topics: Carbohydrate Metabolism; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Fructose; Galactose; Genomic Instability; Humans; Micronucleus Tests; Mutagenicity Tests; Sucrose; Sugars | 2019 |
Differences in micronucleus frequency and acrylamide adduct levels with hemoglobin between vegetarians and non-vegetarians.
Topics: Acrylamide; Adult; Body Mass Index; Diet, Vegetarian; DNA Damage; Epoxy Compounds; Erythrocytes; Feeding Behavior; Female; Folic Acid; Genomic Instability; Hemoglobins; Humans; Life Style; Linear Models; Male; Micronucleus Tests; Motor Activity; Sensitivity and Specificity; Sweden; Transferrin; Vegetarians; Vitamin B 12; Young Adult | 2015 |
Folate levels modulate oncogene-induced replication stress and tumorigenicity.
Topics: Animals; Carcinogenesis; DNA Replication; Folic Acid; Genomic Instability; Mice; Oncogenes | 2015 |
MTHFD1 regulates nuclear de novo thymidylate biosynthesis and genome stability.
Topics: Animals; Congenital Abnormalities; Folic Acid; Genomic Instability; Homocysteine; Humans; Immunologic Deficiency Syndromes; Metabolism, Inborn Errors; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Minor Histocompatibility Antigens; Thymidine Monophosphate | 2016 |
Genotoxicity and cytotoxicity of chromium, copper, manganese and lead, and their mixture in WIL2-NS human B lymphoblastoid cells is enhanced by folate depletion.
Topics: B-Lymphocytes; Cell Line; Chromium; Copper; Cytotoxins; DNA Damage; Folic Acid; Genomic Instability; Humans; Manganese; Metals, Heavy; Micronucleus Tests; Mutagens | 2016 |
The interactive effect of alcohol and folic acid on genome stability in human WIL2-NS cells measured using the cytokinesis-block micronucleus cytome assay.
Topics: Cell Death; Cell Line; Cell Proliferation; Cytokinesis; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Folic Acid; Genomic Instability; Humans; Micronucleus Tests | 2008 |
Photobiological implications of folate depletion and repletion in cultured human keratinocytes.
Topics: Cell Line; Comet Assay; DNA Damage; Folic Acid; Folic Acid Deficiency; Genomic Instability; Humans; Keratinocytes; S Phase; Tetrahydrofolates; Ultraviolet Rays; Uracil | 2010 |
Variants in folate pathway genes as modulators of genetic instability and lung cancer risk.
Topics: Aged; Case-Control Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Regulatory Networks; Genetic Predisposition to Disease; Genomic Instability; Glycine Hydroxymethyltransferase; Humans; Linkage Disequilibrium; Lung Neoplasms; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Micronucleus Tests; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Regression Analysis; Tumor Cells, Cultured | 2011 |
Autism Speaks: meeting on folate metabolism and Autism spectrum disorders, March 19-20, 2009, Washington, DC.
Topics: Autistic Disorder; Biological Transport; Brain; Cognition Disorders; District of Columbia; Folic Acid; Genomic Instability; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, N-Methyl-D-Aspartate; Vitamin B 12 | 2011 |
MTHFD1 G1958A, BHMT G742A, TC2 C776G and TC2 A67G polymorphisms and head and neck squamous cell carcinoma risk.
Topics: Betaine-Homocysteine S-Methyltransferase; Brazil; Carcinoma, Squamous Cell; DNA Methylation; Female; Folic Acid; Genomic Instability; Head and Neck Neoplasms; Humans; Logistic Models; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Transcobalamins | 2012 |
Supplemental dietary folic acid has no effect on chromosome damage in erythrocyte progenitor cells of mice.
Topics: Animal Feed; Animals; Chromosome Disorders; Dietary Supplements; DNA Methylation; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Genomic Instability; Male; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Myeloid Progenitor Cells; Pregnancy; Prenatal Exposure Delayed Effects; Reticulocytes; Vitamin B Complex; Weaning | 2012 |
Choline and/or folic acid deficiency is associated with genomic damage and cell death in human lymphocytes in vitro.
Topics: Adult; Apoptosis; Cell Death; Cell Nucleus; Cells, Cultured; Choline; Choline Deficiency; DNA Damage; Female; Folic Acid; Folic Acid Deficiency; Genomic Instability; Humans; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Necrosis | 2012 |
Influence of the antifolate drug Methotrexate on the development of murine neural tube defects and genomic instability.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, Liquid; Comparative Genomic Hybridization; Diet; DNA Copy Number Variations; Dose-Response Relationship, Drug; Embryonic Development; Enzyme Inhibitors; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Genomic Instability; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neural Tube; Neural Tube Defects; Pregnancy; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Tandem Mass Spectrometry; Tetrahydrofolate Dehydrogenase | 2013 |
Methylenetetrahydrofolate reductase C677T polymorphism, folic acid and riboflavin are important determinants of genome stability in cultured human lymphocytes.
Topics: Adult; Aged; Cell Death; Cell Division; Cell Nucleus; Cells, Cultured; Culture Media; Female; Folic Acid; Gene Rearrangement; Genomic Instability; Homocysteine; Homozygote; Humans; Lymphocytes; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Polymorphism, Genetic; Riboflavin | 2004 |
MTHFR C677T has differential influence on risk of MSI and MSS colorectal cancer.
Topics: Adult; Aged; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genomic Instability; Genotype; Germ-Line Mutation; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Microsatellite Repeats; Middle Aged; Phenotype; Polymorphism, Single Nucleotide | 2007 |