folic acid has been researched along with Experimental Leukemia in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (91.30) | 18.7374 |
| 1990's | 4 (8.70) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GOLDIN, A; GREENHOUSE, SW; HUMPHREYS, SR; MANTEL, N; VENDITTI, JM | 1 |
| NICHOL, CA | 1 |
| DENNIS, D; GOLDIN, A; GREENHOUSE, SW; HUMPHREYS, SR; MANTEL, N; VENDITTI, JM | 1 |
| DENNIS, D; GOLDIN, A; HUMPHREYS, SR; MANTEL, N; VENDITTI, JM | 1 |
| KIRSANOVA, VA; VODOLAZSKAIA, NA | 1 |
| GOLDIN, A; HUMPHREYS, ST; MANTEL, N; VENDITTI, JM | 1 |
| LYNCH, TJ; MOLONEY, WC | 1 |
| BRODY, JI; MCKENZIE, D | 1 |
| SLAVIK, K; SOCHMAN, J; SOUCEK, J | 1 |
| MOTYCKA, K; SLAVIK, K; SOUCEK, J | 1 |
| JIRASEK, A; JIRASEK, J; MOTYCKA, K; SLAVIK, K; SOUCEK, J | 1 |
| COX, RP; FRIEND, C; HADDAD, JR; SILBER, R | 1 |
| CRAWFORD, EJ; FRIEDKIN, M; GOLDIN, A; HUMPHREYS, SR; KASHKET, ER | 1 |
| BURCHENAL, JH; JOHNSTON, SF | 1 |
| BURCHENAL, JH; KUSHIDA, MN | 1 |
| Atchley, R; Zimmer, H | 1 |
| Abels, J; Kroes, AC; Lindemans, J | 1 |
| Abels, J; Hagenbeek, A; Kroes, AC; Lindemans, J | 1 |
| Ambaye, RY; Gokhale, SV; Parchure, M | 1 |
| Kelly, DA; Scott, JM; Weir, DG | 1 |
| McCormack, JJ | 1 |
| Woodcock-Mitchell, J; Yang, TJ | 1 |
| Brigle, KE; Kranz, DM; Patrick, TA; Roy, EJ; Spinella, MJ | 1 |
| Albrecht, AM | 1 |
| Bender, RA; Nichols, AP; Warren, RD | 1 |
| Goldin, A | 1 |
| Calvo, N; Cavalcanti, F; Grau-Oliete, MR; Rivera-Fillat, MP | 1 |
| Brigle, KE; Goldman, ID; Houghton, MT; Westin, EH | 1 |
| Bertino, JR; Carotti, S; Coronnello, M; Gerli, A; Mazzei, T; Mini, E; Moroson, BA; Periti, P; Pesciullesi, A | 1 |
| Holland, JF; Kano, Y; Ohnuma, T | 1 |
| Bolanowska, WE; McGuire, JJ; Piper, JR | 1 |
| Abels, J; Kroes, AC; Lindemans, J; Schoester, M | 1 |
| Danenberg, PV; Pogolotti, AL; Santi, DV | 1 |
| Sanada, H; Taguchi, H | 1 |
| Gessner, G; Jenkins, B; Maass, AR; Sosnowski, G; Wiebelhaus, VD | 1 |
| Bukin, IuV; Raushenbakh, MO; Sergeev, AV | 1 |
| Galegov, GA; Shobukhov, VM | 1 |
| Clark, BR; Halpern, BC; Halpern, RM; Hardy, DN; Smith, RA | 1 |
| Bertino, JR; Chello, PL | 1 |
| Goldie, JH; Hill, BT; Price, LA | 1 |
| Montgomery, JA; Shealy, YF; Struck, RF | 1 |
| Crawford, EJ; Friedkin, M; Plante, LT | 1 |
| Bertino, JR; McCullough, JL; O'Brien, P | 1 |
| Motycka, K; Pristoupilová, K; Slavík, K; Soucek, J | 1 |
| Goldin, A; Mead, JA; Wood, HB | 1 |
| Moore, GE; Ulrich, K | 1 |
4 review(s) available for folic acid and Experimental Leukemia
| Article | Year |
|---|---|
Dihydrofolate reductase inhibitors as potential drugs.
Topics: Aminopterin; Animals; Antimalarials; Bacterial Infections; Biological Transport; Drug Interactions; Folic Acid; Folic Acid Antagonists; Helminthiasis; Humans; Immunosuppressive Agents; Leukemia, Experimental; Liver; Methotrexate; Mice; Mycoses; Neoplasms; Protozoan Infections; Psoriasis; Quinazolines; Rats; Receptors, Drug; Trypanosoma cruzi | 1981 |
Studies with high-dose methotrexate--historical background.
Topics: Aminopterin; Animals; Folic Acid; History, 20th Century; Humans; Leucovorin; Leukemia, Experimental; Methotrexate; Mice; Neoplasms; Time Factors | 1978 |
Biochemical modulation of fluoropyrimidines by antifolates and folates in an in vitro model of human leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Floxuridine; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Leukemia, Experimental | 1990 |
Empirical vs. rational approaches in cancer chemotherapy.
Topics: Animals; Enterococcus faecalis; Escherichia coli; Folic Acid; Folic Acid Antagonists; Leukemia, Experimental; Methyltransferases; Mice; Neoplasms; Thymine Nucleotides; Uracil Nucleotides | 1971 |
42 other study(ies) available for folic acid and Experimental Leukemia
| Article | Year |
|---|---|
Effect of delayed administration of citrovorum factor on the antileukemic effectiveness of aminopterin in mice.
Topics: Aminopterin; Animals; Antimetabolites; Folic Acid; Leucovorin; Leukemia, Experimental; Mice | 1954 |
Studies of the mechanism of resistance to folic acid antagonists by leukemic cells.
Topics: Animals; Antimetabolites; Folic Acid; Folic Acid Antagonists; Leukemia, Experimental | 1954 |
Factors influencing the specificity of action of an antileukemic agent (aminopterin); multiple treatment schedules plus delayed administration of citrovorum factor.
Topics: Aminopterin; Animals; Antineoplastic Agents; Folic Acid; Leucovorin; Leukemia, Experimental | 1955 |
Studies on the management of mouse leukemia (L1210) with antagonists of folic acid.
Topics: Animals; Disease Management; Folic Acid; Folic Acid Antagonists; Leukemia; Leukemia, Experimental | 1955 |
[Investigation on the effect of folic acid antagonist 4-aminopteroyl-aminoadipic acid on the development of transplanted leukosis in mice].
Topics: Animals; Folic Acid; Folic Acid Antagonists; Leukemia, Experimental; Mice | 1955 |
Comparison of the relative effectiveness of folic acid congeners against advanced leukemia in mice.
Topics: Animals; Folic Acid; Folic Acid Antagonists; Leukemia; Leukemia, Experimental; Mice | 1957 |
Observations on serum B-12 and folate activity in normal and leukemic rats.
Topics: Animals; Folic Acid; Hematinics; Leukemia; Leukemia, Experimental; Rats; Vitamin B 12; Vitamin B Complex | 1963 |
Synergistic toxicity of triethylene thiophosphoramide and folic acid in the IRC-741 leukemia.
Topics: Folic Acid; Leukemia; Leukemia, Experimental; Thiotepa | 1963 |
Activity changes of some enzyme systems interferring into the metabolism of folic acid in the livers of mice in the course of LaHVUFB leucaemia.
Topics: Animals; Folic Acid; Folic Acid Antagonists; Fructose-Bisphosphate Aldolase; Leukemia; Leukemia, Experimental; Liver; Mice; Oxidoreductases; Transferrin | 1963 |
ACTIVITY CHANGES OF SOME ENZYME SYSTEMS INTERFERING IN FOLIC ACID METABOLISM IN THE COURSE OF MOUSE LEUKAEMIA OF AKR-STRAIN.
Topics: Aldehyde-Lyases; Animals; Folic Acid; Folic Acid Antagonists; Leukemia; Leukemia, Experimental; Liver; Metabolism; Mice; Mice, Inbred AKR; Oxidoreductases; Research; Transferases | 1964 |
THE TREATMENT OF EXPERIMENTAL MOUSE HEMOBLASTOSIS. I. THE EFFECT OF SOME NEW FOLIC ACID ANTIMETABOLITES ON CELL TRANSPLANTED LEUKEMIA IN MICE OF THE AKR STRAIN.
Topics: Aminopterin; Animals; Antimetabolites; Antineoplastic Agents; Folic Acid; Leukemia; Leukemia, Experimental; Leukocyte Count; Methotrexate; Mice; Mice, Inbred AKR; Pharmacology; Research; Toxicology | 1964 |
ENZYME STUDIES IN VIRUS-INDUCED NEOPLASMS. I. THE EFFECT OF A MURINE LEUKEMIA ON ENZYMES OF ONE-CARBON METABOLISM AND ON PHOSPHOMONOESTERASES.
Topics: Alkaline Phosphatase; Animals; Carbon; Esterases; Folic Acid; Histocytochemistry; Leukemia; Leukemia Virus, Murine; Leukemia, Experimental; Ligases; Liver; Metabolism; Mice; Oxidoreductases; Phosphoric Monoester Hydrolases; Research; Spleen; Splenectomy; Thymidine | 1964 |
ON THE SIMILARITY OF DIHYDROFOLATE REDUCTASES FROM AMETHOPTERIN-SENSITIVE AND AMETHOPTERIN-RESISTANT MOUSE LEUKEMIA (L1210) CELLS.
Topics: Animals; Benzoates; Enzyme Inhibitors; Folic Acid; Leukemia; Leukemia, Experimental; Methotrexate; Mice; NADP; Oxidoreductases; Pharmacology; Research; Sodium Chloride; Tetrahydrofolate Dehydrogenase | 1964 |
Chemotherapy of leukemia; effect of folic acid derivatives on transplanted mouse leukemia.
Topics: Animals; Folic Acid; Humans; Leukemia; Leukemia, Experimental; Vitamin B Complex; Vitamins | 1949 |
Prevention of chemotherapeutic effects of 4-amino-N10-methyl-pteroylglutamic acid on mouse leukemia by pteroylglutamic acid.
Topics: Amino Acids; Animals; Biomedical Research; Folic Acid; Leukemia; Leukemia, Experimental | 1949 |
Potential anticancer agents V. Synthesis of folic acid and pteroic acid analogs derived of caffeine and theophylline.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Caffeine; Folic Acid; Leukemia, Experimental; Mice; Theophylline | 1966 |
Synergistic growth inhibiting effect of nitrous oxide and cycloleucine in experimental rat leukaemia.
Topics: Amino Acids; Animals; Cycloleucine; Deoxyuridine; Drug Synergism; Folic Acid; Leukemia, Experimental; Leukocyte Count; Liver; Male; Nitrous Oxide; Organ Size; Rats; Rats, Inbred BN; S-Adenosylmethionine; Spleen; Vitamin B 12 | 1984 |
Nitrous oxide reduces growth of experimental rat leukemia.
Topics: Animals; Cell Division; Folic Acid; Kinetics; Leukemia, Experimental; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Nitrous Oxide; Organ Size; Rats; Vitamin B 12 | 1984 |
Combination of anticancer agents with folic acid in the treatment of murine leukaemia P388.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation, Preclinical; Drug Synergism; Fluorouracil; Folic Acid; Leukemia P388; Leukemia, Experimental; Methotrexate; Mice; Mitomycins | 1984 |
Increased folate catabolism in mice with ascitic tumours.
Topics: Animals; Ascitic Fluid; Folic Acid; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains | 1983 |
Effect of antiserum on leukemia L5178Y cells: [3H]thymidine incorporation does not reflect DNA synthesis.
Topics: Animals; Antibodies, Neoplasm; Biological Transport; DNA Replication; DNA, Neoplasm; Folic Acid; Leukemia, Experimental; Mice; Thymidine; Thymidine Kinase; Thymidylate Synthase | 1982 |
Conjugates of folate and anti-T-cell-receptor antibodies specifically target folate-receptor-positive tumor cells for lysis.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Carrier Proteins; Cell Line; Cytotoxicity, Immunologic; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Immunoconjugates; Kinetics; Leukemia L1210; Leukemia, Experimental; Mice; Mice, Inbred DBA; Receptors, Antigen, T-Cell; Receptors, Cell Surface; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1995 |
Regulatory control of tetrahydrofolate coenzymes in folate auxotrophs.
Topics: Animals; Culture Media; Folic Acid; Folic Acid Antagonists; In Vitro Techniques; Leucovorin; Leukemia, Experimental; Methotrexate; Mice; Streptococcus; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates | 1977 |
Membrane transport of methotrexate in human lymphoblastoid cells.
Topics: Animals; Antimetabolites; Biological Transport, Active; Cell Line; Cell Membrane; Folic Acid; Humans; Kinetics; Leucovorin; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocytes; Methotrexate; Temperature | 1978 |
Simultaneous changes in various mechanisms that mediate the cell incorporation of folate compounds account for low levels of resistance to methotrexate.
Topics: Animals; Carrier Proteins; Cell Line; Drug Resistance; Folate Receptors, GPI-Anchored; Folic Acid; Leukemia, Experimental; Male; Mice; Receptors, Cell Surface; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tumor Cells, Cultured | 1992 |
Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Blotting, Northern; Blotting, Southern; Carrier Proteins; Cloning, Molecular; DNA; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation; Gene Rearrangement; Glycosylation; Leukemia, Experimental; Mice; Molecular Sequence Data; Protein Biosynthesis; Protein Processing, Post-Translational; Receptors, Cell Surface; Restriction Mapping; Sequence Alignment; Tumor Cells, Cultured | 1991 |
Folate requirements of methotrexate-resistant human acute lymphoblastic leukemia cell lines.
Topics: Biological Transport; Cell Line; Drug Resistance; Folic Acid; Humans; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Nutritional Requirements; Quinazolines; Trimetrexate | 1986 |
Structural specificity of inhibition of human folylpolyglutamate synthetase by ornithine-containing folate analogs.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Folic Acid; Humans; Leukemia, Experimental; Methotrexate; Ornithine; Peptide Synthases; Rabbits; Structure-Activity Relationship; Tumor Cells, Cultured | 1988 |
Enhanced therapeutic effect of methotrexate in experimental rat leukemia after inactivation of cobalamin (vitamin B12) by nitrous oxide.
Topics: Animals; Blood Cell Count; Deoxyuridine; Drug Administration Schedule; Drug Synergism; Folic Acid; Leukemia, Experimental; Male; Methotrexate; Nitrous Oxide; Rats; Thymine Nucleotides; Vitamin B 12 | 1986 |
Kinetics and mechanism of interaction of 10-propargyl-5,8-dideazafolate with thymidylate synthase.
Topics: Antineoplastic Agents; Carbon Radioisotopes; Deoxyuracil Nucleotides; Folic Acid; Kinetics; Leukemia, Experimental; Protein Denaturation; Quinazolines; Spectrophotometry, Ultraviolet; Thymidylate Synthase; Tritium | 1986 |
Folic acid metabolism in Rauscher murine leukemia and effect of methotrexate on the blood picture.
Topics: Animals; Folic Acid; Injections, Intravenous; Leukemia, Experimental; Leukemia, Lymphoid; Liver; Methotrexate; Mice; Mice, Inbred BALB C; Plasma; Rauscher Virus; Spleen | 1974 |
Effect of triamterene on folic reductase activity and reproduction in the rat.
Topics: Animals; Culture Techniques; Diet; Female; Fertility; Fetus; Folic Acid; Folic Acid Antagonists; Leukemia Virus, Murine; Leukemia, Experimental; Pregnancy; Rats; Reproduction; Triamterene | 1967 |
[New route of regulating folic acid metabolism in experimental chemotherapy of leukoses and malignant neoplasms].
Topics: Animals; Carcinoma, Hepatocellular; Cycloserine; Female; Folic Acid; Leukemia, Experimental; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Methotrexate; Mice; Neoplasms, Experimental; Pyridoxal Phosphate; Rats; Spleen; Tetrahydrofolate Dehydrogenase; Transferases | 1971 |
[Effect of folic acid and methotrexate on the reproduction of the Rauscher leukemia virus].
Topics: Animals; Cells, Cultured; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Embryo, Mammalian; Folic Acid; Leukemia, Experimental; Methotrexate; Mice; Mice, Inbred BALB C; Rauscher Virus; Time Factors; Virus Cultivation; Virus Replication | 1974 |
The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture.
Topics: Animals; Breast; Carcinoma 256, Walker; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Culture Media; Female; Fibroblasts; Folic Acid; Homocystine; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid; Liver; Male; Methionine; Mice; Prostate; Rats; Vitamin B 12 | 1974 |
Dependence of 5-methyltetrahydrofolate utilization by L5178Y murine leukemia cells in vitro on the presence of hydroxycobalamin and transcobalamin II.
Topics: Animals; Cell Division; Cobalt Isotopes; Coenzymes; Culture Techniques; Folic Acid; Leukemia, Experimental; Methionine; Mice; Tetrahydrofolates; Time Factors; Vitamin B 12 | 1973 |
Studies concerned with overcoming resistance to methotrexate: a comparison of the effects of methotrexate and 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine (BW50197) on the colony forming ability of L5178Y cells.
Topics: Animals; Cell Line; Chlorobenzenes; Diamines; Folic Acid; Folic Acid Antagonists; Leukemia, Experimental; Methotrexate; Mice; Pyrimethamine; Pyrimidines | 1973 |
Potential folic acid antagonists. 5. Synthesis and biologic evaluation of N 10 -deazapteroic acid and N 10 -deazafolic acid and their 9,10-dehydro derivatives.
Topics: Animals; Antimalarials; Binding Sites; Chemical Phenomena; Chemistry; Enterococcus faecalis; Folic Acid; Folic Acid Antagonists; Humans; Leukemia, Experimental; Liver; Mice; Plasmodium; Pterins; Skin; Time Factors | 1971 |
Inhibition of growth of leukemia cells by enzymic folate depletion.
Topics: Animals; Carboxypeptidases; Carcinoma 256, Walker; Cell Line; Culture Media; Depression, Chemical; Folic Acid; Humans; Hypoxanthines; In Vitro Techniques; Leucovorin; Leukemia L1210; Leukemia, Experimental; Methotrexate; Pseudomonas; Serine; Thymidine | 1971 |
The treatment of experimental mouse hemoblastosis. VI.
Topics: Aminopterin; Animals; Bromine; Coenzymes; Dactinomycin; Folic Acid; Leukemia, Experimental; Liver; Spleen | 1968 |
Relationship of structure to antitumor activity in compounds related to folic acid.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Folic Acid; Leukemia, Experimental; Mice; Neoplasms, Experimental | 1968 |
In vitro culture of IRC 741 rat leukemia.
Topics: Animals; Chromosomes; Culture Techniques; Folic Acid; Leukemia, Experimental; Rats | 1965 |