Page last updated: 2024-08-17

folic acid and Colorectal Cancer

folic acid has been researched along with Colorectal Cancer in 446 studies

Research

Studies (446)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (0.22)	18.7374
1990's	37 (8.30)	18.2507
2000's	194 (43.50)	29.6817
2010's	178 (39.91)	24.3611
2020's	36 (8.07)	2.80

Authors

Authors	Studies
Branco de Barros, AL; Cassali, GD; de Aguiar Ferreira, C; de Alcântara Lemos, J; de Oliveira Silva, J; Fernandes, RS; Miranda, SEM; Nunes, SS; Oliveira, MC; Townsend, DM	1
Beydoun, S; Cabelof, DC; Fardous, AM; Heydari, AR; James, AA; Ma, H; Unnikrishnan, A	1
Guo, W; Li, K; Liu, Y; Wang, W; Yan, S	1
Chang, HJ; Kim, J; Lee, J; Oh, JH; Shin, A; Sohn, DK	1
Baierl, A; Böhm, J; Bours, MJL; Brenner, H; Breukink, SO; Brezina, S; Chang-Claude, J; de Wilt, JHW; Geijsen, AJMR; Gigic, B; Grady, WM; Grünberger, T; Gsur, A; Gumpenberger, T; Habermann, N; Herpel, E; Hoffmeister, M; Holowatyj, AN; Kampman, E; Keulen, ETP; Kiblawi, R; Kok, DE; Koole, JL; Kosma, K; Kouwenhoven, EA; Kvalheim, G; Li, CI; Lin, T; Ose, J; Schirmacher, P; Schneider, M; Schrotz-King, P; Singer, MC; Ueland, PM; Ulrich, AB; Ulrich, CM; Ulvik, A; van Duijnhoven, FJB; van Halteren, HK; van Roekel, EH; Vickers, K; Vogelaar, FJ; Warby, CA; Weijenberg, MP; Wesselink, E	1
Chang, H; Deng, Z; Fu, H; He, J; Li, C	1
Barták, BK; Felletár, I; Galamb, O; Igaz, P; Kalmár, A; Márkus, E; Micsik, T; Molnár, B; Nagy, ZB; Papp, M; Szigeti, KA; Takács, I; Tulassay, Z; V Patai, Á; Valcz, G; Zsigrai, S	1
Baltazar, F; Gomes, S; Preto, A; Silva, E; Teixeira-Guedes, C	1
Chen, Q; Deng, R; Gui, S; Guo, Y; Jin, X; Lu, X; Su, L; Wang, J; Wang, S; Wang, Z; Xin, H; Xu, Y; Zeng, J; Zhang, L; Zhu, B	1
Deng, F; Deng, W; Engel, A; Goldys, E; Sang, R	1
Che, MM; Fang, YJ; Li, X; Ma, T; Wu, QX; Xu, L; Zhang, CX; Zhou, RL	1
Albanes, D; Berndt, S; Bien, SA; Buchanan, DD; Campbell, PT; Casey, G; Chan, AT; Conti, D; Figueiredo, JC; Gallinger, SJ; Gauderman, WJ; Giles, GG; Gruber, SB; Haas, CB; Hayes, RB; Hsu, L; Huang, WY; Jenkins, MA; Kim, AE; Le Marchand, L; Lewinger, JP; Li, L; Lin, Y; Lindor, NM; Milne, RL; Moreno, V; Nan, H; Nassir, R; Newcomb, PA; Peters, U; Petersen, P; Potter, JD; Rennert, G; Sakoda, LC; Slattery, ML; Su, YR; Wang, X; Weinstein, SJ; White, E; Wolk, A; Woods, MO	1
Du, M; Mclaughlin, JR; Parfrey, PS; Shariati, M; Vallis, J; Wang, PP; Wang, Y; Zhu, Y	1
Huo, YN; Lee, WS; Wang, HC	1
Baierl, A; Bours, MJ; Brezina, S; Damerell, V; Geijsen, AJMR; Gigic, B; Grady, W; Gsur, A; Gumpenberger, T; Habermann, N; Holowatyj, AN; Kampman, E; Kiblawi, R; Koelsch, T; Kok, DE; Koole, JL; Kvalheim, G; Li, CI; Lin, T; Ose, J; Schneider, M; Ueland, PM; Ulrich, A; Ulrich, C; Ulvik, A; van Duijnhoven, FJ; van Roekel, E; Vickers, K; Weijenberg, M	1
Car, H; Lazny, R; Markiewicz, KH; Milewska, S; Misztalewska-Turkowicz, I; Niemirowicz-Laskowska, K; Sawicka, D; Siemiaszko, G; Szymczuk, D; Wilczewska, AZ	1
Abbasi, M; Kashif, MU; Mahmood, A; Minhas, MU; Munir, A; Shah, SA; Sohail, M	1
Arroyo-Izaga, M; Chávez-Hidalgo, LP; M de Pancorbo, M; Martín-Fernández-de-Labastida, S	1
Cui, K; Fei, B; Huang, Z; Li, C; Ling, F; Sun, S; Teng, P; Yao, S	1
Alegria-Lertxundi, I; Arroyo-Izaga, M; de Pancorbo, MM; Martín-Fernández-de-Labastida, S	1
Ebell, MH; Kurotschka, PK; Serafini, A	1
Askarpour, SA; Doaei, S; Gholamalizadeh, M; Hassanpour Ardekanizadeh, N; Masoumvand, M; Mohammadi, S; Mousavi Mele, M; Mousavi Shalmani, SH; Shekari, S; Vahid, F; Zeinalabedini, M	1
Ahnen, DJ; Baron, JA; Barry, EL; Bresalier, RS; Cole, BF; Haile, RW; McKeown-Eyssen, G; Mott, LA; Passarelli, MN; Rees, JR; Snover, DC; Zhang, D	1
Jain, SK; Rajpoot, K	2
Kaewkungwal, J; Kwanbunjan, K; Panprathip, P; Petmitr, S; Tungtrongchitr, R	1
Goldstein, MR; Mascitelli, L; Rauf, ZH	1
Burke, CA; Mankaney, G; Sutton, RA	1
Abdolalizadeh, J; Bonabi, E; Lotfi, H; Shamekhi, S; Zarghami, N	1
Böhm, J; Bours, MJL; Brezina, S; Geijsen, AJMR; Gigic, B; Gsur, A; Gumpenberger, T; Habermann, N; Hardikar, S; Himbert, C; Holowatyj, AN; Kiblawi, R; Kok, DE; Koole, JL; Lin, T; Ose, J; Playdon, M; Schneider, M; Schrotz-King, P; Ueland, PM; Ulrich, A; Ulrich, CM; Ulvik, A; van Duijnhoven, FJB; van Roekel, EH; Warby, CA; Weijenberg, MP	1
Cheng, Y; He, Y; Hu, Y; Ji, J; Zheng, S	1
Abdolahi, HM; Alizadeh, BZ; Dastgiri, S; de Bock, GH; Dolatkhah, R; Moazzen, S	1
Arbely, E; Chen, X; Du, P; Huang, Z; Liu, CY; Qi, Q; Wan, X; Wang, C; Xiang, S; Yu, W; Zhou, D	1
Bardou, M; Barkun, AN; Chapelle, N; Martel, M; Toes-Zoutendijk, E	1
Bonala, S; Gupta, MK; Vadde, R	1
Araújo, AA; Chan, AB; Cruz, LJ; de Araújo Júnior, RF; de Carvalho, TG; de Geus-Oei, LF; Oliveira, ALCSL; Schomann, T; Souza, SVP; Zerillo, L	1
Baade, P; Spencer, LB; van der Pols, JC	1
An, J; Cheng, K; Hu, YG; Liu, B; Xuan, Y; Yang, XQ; Zhang, RY; Zhao, YD	1
Giovannucci, EL; Li, Y; Liang, L; Smith-Warner, SA; Song, M; Song, R; Wang, F; Willett, WC; Wu, K; Wu, Y; Zhang, X	1
de Gramont, A; Glimelius, B; Marshall, J; Stintzing, S; Yoshino, T	1
Chu, D; Guo, J; Han, S; O'Driscoll, CM; Song, L; Sun, B; Sun, D; Wang, L; Xiao, F; Yu, Z; Zou, Y	1
Chen, Z; He, Y; Huang, S; Song, J; Tu, X; Wang, L; Zhang, Z	1
Chu, X; Sun, P; Tang, Y; Yang, Y; Zhang, N; Zhao, Y	1
Campos-Outcalt, D	1
Feng, HC; Hsu, SH; Huang, RS; Kuo, CS; Lan, WY; Lin, JY; Sun, DP; Tian, YF	1
Alizadeh, BZ; Dastgiri, S; de Bock, GH; Dolatkhah, R; Moazzen, S; Shaarbafi, J; Tabrizi, JS	1
Buys, SS; Gren, LH; Hashibe, M; Kawakita, D; La Vecchia, C; Lee, YA	1
Arima, H; Elamin, KM; Higashi, T; Motoyama, K; Tokuda, A; Yamashita, Y	1
Baron, JA; Barry, EL; Bresalier, RS; Gangar, P; Karagas, MR; McKeown-Eyssen, G; Passarelli, MN; Rees, JR; Zhang, D	1
Gylling, B; Häggström, J; Hallmans, G; Johansson, I; Midttun, Ø; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Ulvik, A; Van Guelpen, B	1
Al-Ramadhani, H; Al-Yacoub, S; Kadi, T; Tantawi, DA; Yousef, AM; Zawiah, M	1
Asante, I; Chui, D; Liu, S; Louie, SG; Pei, H; Yoo, E; Zhou, E	1
Chan, AK; Chan, SL; Ma, BB	1
Coppedè, F; Lazzarotti, A; Migliore, L; Spisni, R; Stoccoro, A	1
Ajaj, AR; Al-Hiary, R; Al-Yacoub, S; Kadi, T; Majdalawi, K; Mukred, R; Tantawi, D; Yousef, AM; Yousef, M; Zawiah, M	1
Kok, DE; McKay, JA; Steegenga, WT	1
de Groot, LCPGM; Kiefte-de Jong, JC; Lemmens, V; Oliai Araghi, S; Stricker, BH; Swart, KMA; Uitterlinden, AG; van der Velde, N; van Dijk, SC; van Laarhoven, HW; van Schoor, NM	1
Decker, T; Denzlinger, C; Fischer von Weikersthal, L; Freiberg-Richter, J; Giessen-Jung, C; Graeven, U; Heinemann, V; Held, S; Jung, A; Kirchner, T; Modest, DP; Peuser, B; Peveling Genannt Reddemann, C; Schenk, M; Schuch, G; Schwaner, I; Stahler, A; Stintzing, S; Uhlig, J; Vehling-Kaiser, U	1
Hsu, SP; Huo, YN; Lee, WR; Lee, WS; Ting, PC	1
Kampman, E; Kok, DE; Smid, EJ; Steegenga, WT; Ulrich, CM; Zoetendal, EG	1
Asante, I; Chui, D; Conti, DV; Liu, S; Louie, SG; Pei, H; Yoo, E; Zhou, E	1
Hasanzadeh, M; Jouyban, A; Shadjou, N; Soleymani, J; Somi, MH	1
Christy-Bittel, J; Ciardiello, F; Cuyle, PJ; Desai, J; Elez, E; Fakih, M; Gollerkeri, A; Grothey, A; Huijberts, S; Kopetz, S; Maharry, K; Montagut, C; Peeters, M; Sandor, V; Schellens, JHM; Tabernero, J; Van Cutsem, E; Wasan, H; Yaeger, R; Yoshino, T	1
Arthur, RS; Kirsh, VA; Rohan, TE	1
Dajani, O; Glimelius, B; Guren, TK; Hamfjord, J; Johansen, JS; Kure, EH; Lingjærde, OC; Pallisgaard, N; Pfeiffer, P; Sorbye, H; Spindler, KG; Tveit, KM	1
Aguiar Junior, S; Carraro, DM; Ferrari, A; Torrezan, GT	1
Carlsson, G; Gustavsson, B; Odin, E; Sondén, A; Wettergren, Y	2
Basen-Engquist, K; Coletta, AM; Gatus, LA; Gilchrist, SC; Krause, KJ; Lu, KH; Lynch, PM; Pande, M; Peterson, SK; Rodriguez-Bigas, MA; Schembre, SM; Strong, LL; Vilar, E; You, YN	1
Abbadi, RA; Arno, M; Astarloa, EA; Emery, P; Ewins, M; Green, C; Pufulete, M; Sanders, T	1
Ardizzone, S; Danese, S; Gasche, C; Hernández, V; Kariv, R; Marti-Gallostra, M; Myrelid, P; Sebastian, S; Spinelli, A; Toruner, M; Tsianos, E; van der Meulen-de Jong, AE; Yuksel, ES	1
Chen, HM; Chen, XY; Chen, YX; Fang, DC; Fang, JY; Gao, QY; Ge, ZZ; Sheng, JQ; Tang, JT; Wang, YC; Wang, ZH; Yu, CG; Zheng, P	1
Cho, E; Fuchs, CS; Giovannucci, EL; Lee, JE; Nan, H; Rimm, EB	1
Deng, L; Leclerc, D; Lévesque, N; Pham, DN; Rozen, R	1
Baglietto, L; Bassett, JK; English, DR; Giles, GG; Hodge, AM; Hopper, JL; Severi, G	1
Chuang, SC; Eussen, SJ; Gunter, MJ; Norat, T; Rota, M; Ueland, PM; Vineis, P; Vollset, SE; Zeleniuch-Jacquotte, A; Ziegler, RG	1
Ashmore, JH; Berg, AS; Gallagher, CJ; Hartman, TJ; Lazarus, P; Lesko, SM; Miller, PE; Muscat, JE	1
Kamijo, A; Nagase, H; Okada, K; Sadahiro, S; Suzuki, T; Tanaka, A; Uchida, J	1
Cho, YK; Chong, SY; Hong, SP; Hwang, SG; Jang, MJ; Jeon, YJ; Ji, YG; Kim, JW; Kim, NK; Oh, D	1
Ayed, I; Emery, P; Gheorghiu, A; Hanks, J; Harris, J; Kukreja, N; Liu, CL; Pufulete, M; Rogers, C	1
Basile, F; Biondi, A; Drago, F; Gangi, S; Grosso, G; Marventano, S; Mistretta, A; Nolfo, F; Rametta, S	1
Chiang, FF; Huang, SC; Huang, YC; Lan, YC; Wang, HM; Yang, MH	1
Besznyák, I; Bursics, A; Dede, K; Fekete, A; Kőszegi, G; Láng, I; Mersich, T; Mester, G; Pörneczi, B	1
Anderson, KE; Cerhan, JR; French, AJ; Haile, RW; Harnack, LJ; Jewel Samadder, N; Limburg, PJ; Lynch, CF; Potter, JD; Slager, SL; Smyrk, TC; Thibodeau, SN; Tillmans, LS; Vierkant, RA; Wang, AH	1
Futami, K; Ichimiya, H; Ikejiri, K; Kakeji, Y; Kono, S; Maehara, Y; Maekawa, T; Morita, M; Ohnaka, K; Okamura, T; Takenaka, K; Tanaka, M; Terasaka, R; Toyomura, K; Ueki, T; Yasunami, Y; Yin, G; Yoshimitsu, S	1
Kawano, Y; Taniai, N; Uchida, E; Ueda, J; Yoshida, H; Yoshioka, M	1
Han, SH; Lee, J	1
Chiarugi, M; Consolini, R; Coppedè, F; Failli, A; Fontanini, G; Legitimo, A; Lopomo, A; Migheli, F; Migliore, L; Seccia, M; Sensi, E; Servadio, A; Spisni, R; Zocco, G	1
Giovannucci, EL; Keum, N	1
Azoulay, D; Calderaro, J; Zafrani, ES	1
Jennings, BA; Willis, G	1
Firozian, F; Hassanzadeh, F; Sadeghi-Aliabadi, H; Varshosaz, J	1
Cai, Q; Gao, J; Li, H; Shrubsole, MJ; Shu, XO; Takata, Y; Wagner, C; Wu, J; Xiang, YB; Zheng, W	1
Belshaw, NJ; Johnson, IT	1
Gylling, B; Hallmans, G; Hultdin, J; Johansson, I; Palmqvist, R; Schneede, J; Ueland, PM; Van Guelpen, B	1
Ashbeck, EL; Gerner, EW; Thompson, PA; Thomson, CA; Vargas, AJ	1
Keenan, E; Manne, SL; Myers, RE; Ross, E; Ruth, K; Sifri, R; Weinberg, DS; Ziring, B	1
Baba, Y; Chan, AT; Fuchs, CS; Giovannucci, EL; Inamura, K; Kim, SA; Mima, K; Nishihara, R; Ogino, S; Qian, ZR; Schernhammer, ES; Sukawa, Y; Wang, M; Wu, K; Yamauchi, M; Zhang, X	1
Chen, FP; Chiang, FF; Huang, SC; Huang, YC; Wang, HM	1
Mehta, M; Shike, M	1
Beresford, SA; Brown, E; Cheng, TY; Green, R; Miller, JW; Neuhouser, ML; Rohan, T; Shikany, JM; Song, X; Thomson, CA; Ulrich, CM; Vitolins, MZ; Zheng, Y	1
Befekadu, R; Farkas, SA; Hahn-Strömberg, V; Nilsson, TK	1
Buscema, M; Coppedè, F; Grossi, E; Lopomo, A; Migliore, L; Spisni, R	1
Boyd, L; Choi, JH; Kim, J; Lucock, M; Martin, C; Ng, X; Skinner, V; Veysey, M; Wai, R; Woo, HD; Yates, Z	1
Aguiar, S; de Carvalho, AM; Ferrari, A; Marchioni, DM; Steluti, J; Teixeira, J	1
Hwang, SG; Jang, HG; Jeon, YJ; Kim, JO; Kim, JW; Kim, NK; Kwon, SW; Oh, D; Oh, J; Park, HM	1
Bailey, LB; Beresford, SA; Brown, EC; Caudill, MA; Cheng, TY; Duggan, DJ; Galbraith, RL; Green, R; Habermann, N; Makar, KW; Maneval, DR; Miller, JW; Neuhouser, ML; Poole, EM; Song, X; Toriola, AT; Ulrich, CM; Zheng, Y	1
Du, H; Du, M; Qin, T; Shu, Y; Wang, M; Zhu, L	1
Cho, SH; Jeon, YJ; Kim, JO; Kim, JW; Kim, NK; Ko, JJ; Oh, D; Oh, J; Yoo, JK	1
Ahnen, DJ; Baron, JA; Barry, EL; Bradshaw, PT; Bresalier, RS; Fedirko, V; Figueiredo, JC; Milne, GL; Sandler, RS	1
Cho, E; Fuchs, CS; Giovannucci, EL; Paul, L; Rosner, B; Selhub, J; Townsend, MK; Willett, WC; Zhang, X	1
Cao, Y; Chan, AT; Fuchs, CS; Giovannucci, E; Inamura, K; Kim, SA; Lochhead, P; Meyerhardt, JA; Mima, K; Nishihara, R; Ogino, S; Qian, ZR; Sukawa, Y; Wu, K; Zhang, X	1
Amin, MC; Amjad, MW; Butt, AM; Iyer, AK; Katas, H; Kesharwani, P	1
Angelini, S; Festi, D; Hrelia, P; Maffei, F; Musti, M; Ravegnini, G; Sammarini, G; Simeon, V; Zenesini, C; Zolezzi Moraga, JM	1
Arteta, B; Benedicto, A; Hernandez-Unzueta, I; Márquez, J; Mena, J; Olaso, E; Sanz, E	1
Pot, GK; van Dijk, M	1
Boyd, L; Choi, JH; Lucock, M; Martin, C; Ng, X; Skinner, V; Veysey, M; Wai, R; Yates, Z	1
Burr, NE; Hull, MA; Subramanian, V	1
Barcella, W; Bonetti, M; Cole, BF; Gelber, RD; Lazar, A; Wang, XV; Yip, WK	1
Lei, QY; Liu, YB; Wang, J; Xu, YY; Yang, HB; Zhang, M; Zhang, Y; Zhao, XN; Zhu, ZH	1
Kuo, CT; Lee, WS	1
Chen, HM; Ding, H; Fang, JY; Gao, QY	1
Gylling, B; Häggström, J; Hallmans, G; Hultdin, J; Johansson, I; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Van Guelpen, B	1
Ho, C; Jonker, D; Rayson, D; Stitt, L; Tokmakejian, S; Tomiak, A; Vincent, MD; Winquist, E; Yan, M	1
Budhathoki, S; Hidaka, A; Inoue, M; Iwasaki, M; Sasazuki, S; Sawada, N; Shimazu, T; Svensson, T; Tsugane, S; Yamaji, T	1
Colvin, H; Doki, Y; Hata, T; Ishii, H; Kawamoto, K; Konno, M; Koseki, J; Miyo, M; Mizushima, T; Mori, M; Nishida, N; Nishimura, J; Takemasa, I; Tsunekuni, K	1
Alitheen, NBM; Biabanikhankahdani, R; Ho, KL; Tan, WS	1
Mason, JB; Tang, SY	1
Dulai, PS; Gupta, S; Khera, R; Limburg, PJ; Marquez, E; Murad, MH; Prokop, LJ; Singh, S	1
Gylling, B; Häggström, J; Hallmans, G; Johansson, I; Magne Ueland, P; Myte, R; Palmqvist, R; Schneede, J; Van Guelpen, B	1
Boynton, A; Liu, AY; Luebeck, EG; Moolgavkar, SH; Ulrich, CM	1
Bocquet, A; Bresson, JL; Briend, A; Chouraqui, JP; Darmaun, D; Dupont, C; Frelut, ML; Ghisolfi, J; Girardet, JP; Goulet, O; Putet, G; Rieu, D; Rigo, J; Turck, D; Vidailhet, M	1
Chan, JA; Fuchs, CS; Giovannucci, EL; Meyerhardt, JA; Ng, K; Selhub, J; Wei, EK; Wolpin, BM	1
Hosseini, SV; Izadpanah, A; Malek-Hosseini, SA; Mojallal, M; Mokarram, P; Naghibalhossaini, F; Saberi Firoozi, M; Salahi, H; Talei, A	1
Choi, SW; Liu, Z; Mason, JB	1
Axelrod, BN; Jaszewski, R; Kucuk, O; Levi, E; Majumdar, AP; Misra, S; Naumoff, JA; Patel, BB; Tobi, M; Ullah, N	1
Barrett, JH; Bishop, T; Carey, FA; Forman, D; Key, TJ; Lightfoot, TJ; Northwood, EL; Smith, G; Steele, RJ; Wilkie, MJ; Wolf, R	1
Ahnen, DJ; Ali, I; Baron, JA; Barry, EL; Figueiredo, JC; Grau, MV; Haile, RW; Levine, AJ; Midttun, O; Munroe, D; Sandler, RS; Tsang, S; Ueland, PM	1
Kim, YI	5
Ulrich, CM	2
Ahnen, D; Ali, IU; Baron, JA; Barry, EL; Cole, BF; Haile, RW; Levine, AJ; Munroe, DJ; Saibil, F; Tsang, S; Ueland, P; Wallace, K	1
Ahnen, DJ; Baron, JA; Barry, EL; Bond, J; Bresalier, RS; Byers, T; Figueiredo, JC; Grau, MV; Haile, RW; Levine, AJ; McKeown-Eyssen, GE; Sandler, RS; Summers, RW; Ueland, PM	1
Albanes, D; Graubard, B; Lim, U; Selhub, J; Stolzenberg-Solomon, R; Taylor, PR; Virtamo, J; Weinstein, SJ	1
Brito, M; Carmona, B; Carolino, E; Cravo, M; Fidalgo, P; Gonçalves, S; Guerreiro, CS; Leitão, CN	1
de Vogel, S; Dindore, V; Goldbohm, RA; van den Brandt, PA; van Engeland, M; Weijenberg, MP	1
Choi, SW; Mason, JB; Sauer, J	1
Houlston, RS; Hubner, RA	1
Chen, YX; Fang, JY; Lu, R; Sun, DF; Tian, XQ; Wang, X; Zhao, SL	1
Albanes, D	1
Iwasaki, M; Sakamoto, H; Sasazuki, S; Tsugane, S; Yamaji, T; Yoshida, T	1
Giovannucci, E; Marshall, JR; Martínez, ME	1
Eklöf, V; Hallmans, G; Hultdin, J; Johansson, I; Palmqvist, R; Van Guelpen, B	1
Deng, L; Lawrance, AK; Rozen, R	1
Cai, Q; Chow, WH; Gao, J; Gao, YT; Rothman, N; Shrubsole, MJ; Shu, XO; Wagner, C; Yang, G; Zheng, W	1
Al-Ghnaniem, R; Ally, MS; Pufulete, M	1
Baron, JA; Bresalier, RS; Burke, CA; Figueiredo, JC; Grau, MV; Haile, RW; McKeown-Eyssen, GE; Sandler, RS; Summers, RW	1
Mason, JB	2
Giovannucci, E; Lee, IM; Lee, JE; Li, H; Ma, J; Selhub, J; Stampfer, M	1
Baron, JA; Bresalier, RS; Chen, X; Figueiredo, JC; Grau, MV; Haile, RW; Hamdan, R; Issa, JP; Levine, AJ; McKeown-Eyssen, G; Shen, L; Wallace, K	1
Brown, K; Gescher, AJ; Scott, EN; Steward, WP	1
Fukuda, T; Shiroiwa, T; Tsutani, K	1
Croxford, R; Depeint, F; Kim, YI; Lindzon, GM; Medline, A; Sohn, KJ	1
Gil, J; Jałocha, L; Stelmaszuk, T; Wojtuń, S	1
Fukui, Y; Kamijo, A; Maeda, Y; Murayama, C; Ogoshi, K; Oka, T; Sadahiro, S; Sakamoto, E; Suzuki, T; Tanaka, A; Tsukioka, S	1
Goodman, MT; Henderson, BE; Kolonel, LN; Le Marchand, L; Murphy, SP; Nomura, AM; Selhub, JS; Tiirikainen, M; White, KK; Wilkens, LR	1
Pai, C; Sharif, O; Silverman, AL; Tang, J	1
Arpicco, S; Brusa, P; Cattel, L; Dosio, F; Stella, B	1
Berglund, A; Björkegren, K; Byström, P; Johansson, L; Larsson, A	1
Ahnen, DJ; Ali, IU; Baron, JA; Barry, EL; Bresalier, RS; Burke, C; Grau, MV; Gui, J; McKeown-Eyssen, GE; Munroe, DJ; Saibil, F; Sandler, RS; Sansbury, LB; Tsang, S	1
Ibrahim, EM; Zekri, JM	1
Ahnen, DJ; Baron, JA; Barry, EL; Bresalier, RS; Cushman, M; Ho, GY; McKeown-Eyssen, G; Rohan, TE; Saibil, F; Sandler, RS; Xue, X	1
Fuchs, CS; Giovannucci, E; Kawasaki, T; Ogino, S; Rosner, B; Schernhammer, ES	1
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Fife, J; Frizelle, FA; Hider, PN; Raniga, S	1
Fuchs, CS; Giovannucci, E; Hunter, DJ; Platz, EA; Rosner, BA; Selhub, J; Willett, WC; Wu, K	1
Baron, JA; Chao, WH; Hazra, A; Hunter, DJ; Selhub, J; Ueland, PM	1
Cullman, I; Dahlin, AM; Eklöf, V; Hallmans, G; Henriksson, ML; Hultdin, J; Johansson, I; Palmqvist, R; Van Guelpen, B	1
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Baron, JA; Campbell, PT; Conti, D; Duggan, DJ; Figueiredo, JC; Haile, RW; Hopper, JL; Le Marchand, L; Lee, W; Levine, AJ; Limburg, PJ; Martinez, ME; Newcomb, P; Poynter, JN; Ulrich, CM	1
Haghighi, MM; Mahmoudi, T; Mohebbi, SR; Radpour, R; Vahedi, M; Zali, MR	1
Booth, A; Carroll, C; Cooper, K; Hind, D; Papaioannou, D; Pilgrim, H; Tappenden, P	1
Du, W; Fang, JY; Li, WY; Lu, R	1
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Booth, A; Carroll, C; Cooper, K; Hind, D; Logan, RF; Maguire, C; Papaioannou, D; Squires, H; Tappenden, P	1
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Colditz, GA; Wei, EK; Wolin, KY	1
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Kim, SJ; Mason, JB	1
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Cocroft, J; DiCarlo, M; Manne, SL; Myers, RE; Petrich, A; Sifri, R; Swan, H; Ueland, A; Weinberg, DS; Wilfond, B; Wolf, TA; Ziring, B	1
Baron, JA; Grau, MV; Levine, AJ; Mott, LA; Ueland, PM	1
Arasaradnam, RP	1
Liu, JJ; Ward, RL	1
de Bruïne, AP; de Goeij, AF; de Vogel, S; Goldbohm, RA; Gottschalk, RW; van den Brandt, PA; van Engeland, M; van Schooten, FJ; Weijenberg, MP; Wouters, KA	1
Baron, JA; Mason, JB	1
Baurley, J; Conti, DV; Nijhout, F; Reed, M; Thomas, DC; Ulrich, CM	1
Choi, YK; Chong, SY; Kim, JW; Kim, NK; Oh, D; Park, HM	1
Herman, JG; van Engeland, M	1
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Chin, HC; Lin, CF; Lin, FH; Shieh, MJ; Tsai, HM; Wong, JM; Yang, SJ	1
Baron, JA; Cole, B; Figueiredo, JC; Giovannucci, E; Grainge, MJ; Logan, RF; Mott, LA; Wu, K	1
Kennedy, DA; Koren, G; Matok, I; Moretti, M; Nickel, C; Sarkar, M; Stern, SJ	1
Liu, J; Meagher, AP; Pickford, R; Ward, RL	1
Deng, L; Elmore, CL; Gupta, S; Knock, E; Kruger, W; Krupenko, N; Leclerc, D; Mohan, RD; Rozen, R; Tini, M; Wu, Q	1
Fuchs, CS; Giovannucci, E; Lee, JE; Ma, J; Smith-Warner, SA; Willett, WC; Wu, K	1
Conti, DV; Davis, BD; Edlund, CK; Figueiredo, JC; Haile, RW; Heber, D; Henning, SM; Lee, W; Levine, AJ; Stern, MC; Vandenberg, DJ	1
Holt, PR; Hopkins, ME; Kim, M; Kleinstein, SH; Kopelovich, L; Laird, PW; Lambrecht, RW; Lipkin, M; Liu, Z; Marshall, JR; Mason, JB; Nelson, C; Pendyala, S; Protiva, P	1
Fukushima, M; Kiniwa, M; Nakagawa, F; Saito, H; Sakamoto, E; Tsujimoto, H; Tsukioka, S; Uchida, J	1
Potter, JD	1
Choi, SW; Croxford, R; Kim, YI; Medline, A; Sie, KK; Sohn, KJ; van Weel, J	1
Campbell, PT; Gapstur, SM; Jacobs, EJ; McCullough, ML; Stevens, VL; Sun, J	1
Ayrizono, Mde L; Coy, CS; Guimarães, JL; Lima, CS	1
Fujimori, S; Gudis, K; Kotoyori, M; Ohaki, Y; Sakamoto, C; Takahashi, Y; Tatsuguchi, A	1
Chan, AT; Lee, JE	1
Bronson, RT; Brooks, RS; Ciappio, ED; Crott, JW; Liu, Z; Mason, JB	1
Arulkumaran, S; Talaulikar, VS	1
Assaraf, YG; Azzariti, A; Jansen, G; Paradiso, A; Peters, GJ; Porcelli, L	1
Gibson, TM; Hollenbeck, AR; Mayne, ST; Pfeiffer, RM; Schatzkin, A; Stolzenberg-Solomon, R; Subar, AF; Weinstein, SJ	1
Koren, G	1
Printz, C	1
Bazzoli, F; Ricciardiello, L; Solimando, R	1
Chen, QY; Hui, LL; Li, H; Long, LL; Shen, HL; Xu, WL; Zhu, XL	1
Coppedè, F	1
Chen, HM; Fang, JY; Hong, J; Lin, YW; Lu, R; Ren, LL; Wang, JL; Zhang, YJ	1
Ahn, YO; Cho, YA; Hwang, DY; Jeong, J; Kim, DH; Kim, J; Lee, BH; Lee, HJ; Matsuo, K; Tajima, K	1
Argibay, P; Gómez, DE; Pellegrini, ML	1
Berndt, SI; Burdette, LA; Han, SS; Rosenberg, PS; Selhub, J; Sue, LY; Ziegler, RG	1
Bailey, LB; Berry, RJ; Crider, KS; Yang, TP	1
Fuchs, CS; Giovannucci, E; Hunter, DJ; Lee, IM; Lee, JE; Ma, J; Selhub, J; Stampfer, MJ; Wei, EK; Willett, WC	1
Brauer, N; Lampen, A; Nicken, P; Steinberg, P	1
Jennings, BA; Kwok, CS; Loke, YK; Matthews, V; Wawruch, P; Willis, G	1
Bourke, MJ; Hawkins, NJ; Hesson, LB; Liu, J; Meagher, AP; Molloy, PL; Pimanda, JE; Rand, KN; Ward, RL	1
Martinelli, M; Mattei, G; Montroni, I; Rosati, G; Scapoli, L; Solmi, R; Ugolini, G; Zattoni, D	1
Hao, YS; Liu, HX; Yang, Z; Zhang, XF; Zhao, CL	1
Williams, EA	1
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Iwasaki, M; Le Marchand, L; Miyajima, NT; Pakseresht, M; Sharma, S; Shelton, A; Tsugane, S	1
Elsaed, ET; Fawzy, MM; Kamal, MM; Lotfy, AN; Youssef, OZ	1
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Clapin, HF; Fritschi, L; Heyworth, JS; Iacopetta, B	1
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Ziegler, RG	1
Cook, NR; Giovannucci, E; Lee, IM; Manson, JE; Paul, L; Selhub, J; Song, Y; Zhang, SM	1
Hibi, T; Yajima, T	1
Blom, HJ; Botma, A; Jung, AY; Kampman, E; Kvalheim, G; Lute, C; Midttun, Ø; Nagengast, F; Steegenga, W; Ueland, PM	1
Cai, J; Li, Q; Ling, Y; Ng, KM; Qiu, T; Shan, L; Su, X; Wang, J; Wang, L; Ying, J; Zhao, H	1
Ali, S; Haq, S; Mohammad, R; Sarkar, FH	1
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Jarjanazi, H; Ozcelik, H; Pabalan, N	1
Al-Ghnaniem Abbadi, R; Emery, P; Pufulete, M	1
Baurley, J; Crott, JW; Figueiredo, JC; Haile, RW; Levine, AJ	1
Giovannucci, E	2
Choi, SW; Mason, JB	2
Caprario, L; Chaterjee, N; Flood, A; Lacey, JV; Schairer, C; Schatzkin, A	1
Höffken, K; Kliche, KO; Kubsch, K; Masri-Zada, R; Raida, M	1
Franceschi, S; La Vecchia, C; Negri, E; Pelucchi, C	1
Kampman, E; Keijer, J; Kok, FJ; Nagengast, FM; Pellis, EP; Van den Donk, M	1
Norat, T; Riboli, E	1
Anderson, K; Folsom, AR; Harnack, L; Jacobs, DR; Lazovich, D; Nicodemus, K	1
Aschelter, AM; Bria, E; Cristaudo, A; Garufi, C; Santucci, B; Terzoli, E; Vanni, B	1
Bott, C; Lembcke, B; Stein, J	1
Bagley, PJ; Choi, SW; Dolnikowski, GG; Edmondson, AN; Friso, S; Mason, JB; Smith, DE	1
Eguchi, H; Kiyohara, C; Kono, S; Marugame, T; Oda, T; Shinchi, K; Tsuji, E	1
Bauer, WM; Burke, CA; Lashner, B	1
Al-Ghnaniem, R; Appleby, P; Emery, PW; Gout, S; Leather, AJ; Pufulete, M; Sanders, TA; Terry, C	1
Bailey, LB; Kauwell, GP; Rampersaud, GC	1
Baylin, SB; Brink, M; de Bruïne, AP; de Goeij, AF; Goldbohm, RA; Herman, JG; Roemen, GM; van den Brandt, PA; van Engeland, M; Weijenberg, MP	1
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Croog, VJ; Itzkowitz, SH; Ullman, TA	1
Choi, SW; Crott, JW; Ditelberg, JS; Mason, JB; Ordovas, JM	1
Emery, PW; Pufulete, M; Sanders, TA	1
Calle, EE; Chao, A; Connell, CJ; Jacobs, EJ; McCullough, ML; Rodriguez, C; Thun, MJ	1
Carrier, J; Choi, M; Hwang, SW; Kim, YI; Martin, R; Medline, A; Sohn, KJ	1
Carlsson, G; Gustavsson, B; Larsson, L; Nilsson, S; Odin, E; Spears, CP; Wettergren, Y; Willén, R	1
Courtney, ED; Leicester, RJ; Melville, DM	1
Becheanu, G; Ciocîrlan, M; Croitoru, A; Diculescu, M; Piţigoi, D; Spanache, S	1
Bigler, J; Goode, EL; Potter, JD; Ulrich, CM	1
Little, J; Sharp, L	2
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Axelrod, BN; Finkenauer, R; Hatfield, JS; Jaszewski, R; Kucuk, O; Majumdar, AP; Millar, B; Naumoff, JA; Nogothu, K; Rishi, AK	1
Alberts, DS; Henning, SM; Martínez, ME	1
Bagley, PJ; Choi, SW; Friso, S; Ghandour, H; Mason, JB; Selhub, J	1
Baba, E; Fujishima, H; Harada, M; Kikuchi, I; Mitsugi, K; Miyanaga, O; Nakano, S; Ueda, A	1
Chan, W; Chen, J; Hunter, DJ; Kyte, C; Ma, J; Selhub, J; Valcin, M; Wetmur, JG	1
Fuchs, C; Giovannucci, E; Hankinson, SE; Hunter, DJ; Ma, J; Tranah, GJ	1
Bostick, RM; Boyapati, SM; Coker, A; Fina, MF; Geisinger, KR; Hebert, JR; McGlynn, KA; Roufail, WM; Wargovich, M	1
Basten, G; Duthie, SJ; Little, J; McConnell, J; Narayanan, S; Piyathilake, CJ; Powers, H; Sharp, L	1
Jaszewski, R; Kodali, U; Majumdar, AP	1
Braam, H; Diergaarde, B; Kampman, E; Kok, FJ; Nagengast, FM; Tiemersma, EW; van Muijen, GN	1
Kroesen, A; Pox, C; Schmiegel, W	1
Chen, K; Jin, MJ	1
Medinger, M; Mross, K; Steinbild, S	1
Allen, N; Couto, E; Key, TJ; Roddam, AW; Sanjoaquin, MA	1
Vermel', AE	1
Aparicio, J; Calderero, V; Díaz, R; Guerrero, A; Pellín, L; Segura, A	1
Gill, S; Sinicrope, FA	1
Basten, G; Duthie, SJ; Little, J; Narayanan, S; Powers, H; Sharp, L	1
Mathers, JC	1
Al-Ghnaniem, R; Appleby, P; Emery, PW; Gout, S; Harris, N; Khushal, A; Pufulete, M; Sanders, TA	1
Hahn, A; Ströhle, A; Wolters, M	1
Henderson, BE; Kolonel, LN; Le Marchand, L; Wilkens, LR	1
Bollheimer, LC; Buettner, R; Kullmann, A; Kullmann, F	1
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Buijsse, B; Harryvan, JL; Kampman, E; Kok, FJ; Nagengast, FM; Ocké, MC; van den Berg, SW; van den Donk, M	1
Franco, A; Sikalidis, AK; Solís Herruzo, JA	1
Biasco, G; Di Marco, MC	1
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Chen, K; Kono, S	1
Bruce, WR; Cirocco, M; Giacca, A; Kim, YI; Marcon, N; Minkin, S	1
Casali, A; Gallo Curcio, C; Gionfra, T; Modugno, G; Paoletti, G; Tonachella, R; Tropea, F; Verri, C	1
Powers, HJ	1
Buring, JE; Cook, NR; Lee, IM; Lin, J; Manson, JE; Moore, SC; Zhang, SM	1
Bartholomew, H; Beilby, JP; Divitini, ML; Hung, J; Knuiman, MW; Rossi, E	1
Hanaoka, T; Ishihara, J; Iwasaki, M; Kasuga, Y; Kobayashi, M; Koizumi, Y; Natsukawa, S; Otani, T; Shaura, K; Tsugane, S; Yoshida, T; Yoshimura, K	1
Birk, Y; Morgenstern, S; Niv, Y; Rosman-Urbach, M; Schwartz, B	1
Bingham, S	1
Carlsson, G; Danenberg, PV; Gustavsson, B; Odin, E; Termini, A; Wettergren, Y; Willén, R	1
Beale, P; Clarke, SJ; Horvath, L; Ong, S; Rivory, L; Sharma, R	1
Alberts, DS; Giovannucci, E; Henning, SM; Jacobs, ET; Jiang, R; Martínez, ME; Smith-Warner, SA; Thompson, P	1
Assenat, E; Duffour, J; Ychou, M	1
Mulder, CJ; Terhaar Sive Droste, JS; Tuynman, JB; Van Dullemen, HM	1
Chang, SC; Chen, WC; Jiang, JK; Li, AF; Lin, JK; Lin, TC; Wang, HS; Yang, SH	1
Brockton, NT	2
Chang, SC; Li, AF; Lin, JK; Lin, PC; Wang, HS; Yang, SH	1
Armitage, N; Chau, I; Grainge, M; Houlston, RS; Hubner, RA; Liu, JF; Logan, RF; Muir, KR; Sellick, GS	1
Ahnen, DJ; Baron, JA; Barry, EL; Bhat, S; Burke, CA; Grau, MV; Haile, RW; O'Brien, TG; Sandler, RS	1
Downes, CS; McGlynn, AP; McKelvey-Martin, VJ; McKerr, G; McNulty, H; O'Reilly, SL; Scott, J; Strain, JJ; Wasson, GR	1
Iacopetta, B	1
Alberts, DS; Giovannucci, E; Jacobs, ET; Jiang, R; Klimecki, W; Martínez, ME; Thompson, P	1
Harryvan, JL; Kampman, E; Kok, FJ; van den Donk, M; Visker, MH	1
de Bruïne, AP; de Goeij, AF; de Vogel, S; Goldbohm, RA; Lentjes, MH; Lüchtenborg, M; Roemen, GM; van den Brandt, PA; van Engeland, M; Weijenberg, MP	1
Kune, G; Watson, L	1
Kampman, E; Keijer, J; Kok, FJ; Pellis, L; van den Donk, M; van Engeland, M; Witteman, BJ	1
Chandler, I; Houlston, RS; Hubner, RA; Lubbe, S	1
Fukushima, M; Koizumi, K; Nakagawa, F; Oka, T; Sugimoto, Y; Tsujimoto, H; Tsukioka, S; Uchida, J; Watanabe, T	1
Akhgar, A; Ashktorab, H; Begum, R; Daremipouran, M; Elbedawi, M; Giardiello, FM; Momen, B; Smoot, DT; Zhao, A	1
Alonso-Aperte, E; González, MP; Póo-Prieto, R; Varela-Moreiras, G	1
Fuchs, CS; Giovannucci, EL; Hazra, A; Hunter, DJ; Kraft, P; Wu, K	1
Ahnen, DJ; Allen, JI; Baron, JA; Barry, EL; Beck, GJ; Bond, JH; Bresalier, RS; Burke, CA; Byers, T; Church, TR; Cole, BF; Greenberg, ER; Haile, RW; Mandel, JS; Marcon, N; McKeown-Eyssen, G; Mott, LA; Pearson, LH; Rees, JR; Robertson, DJ; Rothstein, RI; Saibil, F; Sandler, RS; Snover, DC; Summers, RW; Ueland, PM	1
Potter, JD; Ulrich, CM	1
Burakoff, R; Levine, JS	1
Inoue, M; Ishihara, J; Iwasaki, M; Otani, T; Sasazuki, S; Tsugane, S	1
Dallal, G; Dickstein, A; Haggarty, P; Jacques, PF; Mason, JB; Rosenberg, IH; Selhub, J	1
Chattopadhyay, S; Goldman, ID; Min, SH; Tamari, R; Tsai, E; Zhao, R	1
Antal, M; Arató, G; Bereczky, M; Lugasi, A; Pallai, Z; Regöly-Mérei, A; Telek, G	1
Alberts, SR; Ames, M; Goetz, MP; Goldberg, RM; Gornet, MK; Kim, GP; Mahoney, MR; Nicol, SJ; Rubin, J; Weinshilboum, RM	1
Peek, R; Reddy, KR	1
Lim, U; Ziegler, RG	1
Crott, JW; de Boer, SY; Friederich, P; Kampman, E; Keijer, J; Kok, FJ; Mason, JB; Nagengast, FM; Pellis, L; van Bergeijk, JD; van den Donk, M; van Engeland, M	1
van Guelpen, B	1
Baron, JA; Downes, CS; Kampman, E; Kim, YI; Mathers, JC; Muir, KR; Sanderson, P; Stone, E	1
Chae, YK; Yun, JH	1
Al-Ghnaniem, R; Foresti, R; Heaton, N; Peters, J; Pufulete, M	1
Inoue, M; Iwasaki, M; Otani, T; Sasazuki, S; Tsugane, S	1
Arber, N; Das, D; Jankowski, JA	1
Houlston, RS; Hubner, RA; Liu, JF; Logan, RF; Muir, KR; Sellick, GS	1
Armitage, NC; Grainge, MJ; Logan, RF; Muir, KR; Shepherd, VC	1
Solomons, NW	1
Bresalier, RS	1
Starzyńka, T; Wasilewicz, MP	1
Brockton, NT; Cassidy, J; Cotton, SC; Haites, NE; Little, J; Masson, LF; Sharp, L	1
Bayston, R; Hoffbrand, AV; Russell, A; Wald, NJ	1
Dahlin, AM; Hallmans, G; Hultdin, J; Johansson, I; Palmqvist, R; Van Guelpen, B	1
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Iacopetta, B; Jin, M; Kawakami, K; Minamoto, T; Moore, J; Oka, T; Ooyama, A; Ruszkiewicz, A; Watanabe, G	1
Baron, JA; Cole, BF; Kim, YI; Mason, JB; Smith, AD	1
Buda, G; Maggini, V; Orciuolo, E; Petrini, M	1
Arnheim, KE	1
Lundberg, GD	1
Grainge, MJ; Houlston, RS; Hubner, RA; Liu, JF; Logan, RF; Muir, KR	1
Christman, JK; Cravo, ML; Fleet, JC; Kim, YI; Mason, JB; Ordovas, J; Salomon, RN; Selhub, J; Smith, D	1
Chaves, P; Cravo, M; Fidalgo, P; Gouveia-Oliveira, A; Leitao, CN; Mason, JB; Mira, FC; Pereira, AD; Selhub, J	1
D'Avanzo, B; Decarli, A; Ferraroni, M; Franceschi, S; La Vecchia, C; Negri, E	1
Bastian, G; Brienza, S; Comisso, M; Etienne, MC; Lévi, F; Massari, C; Metzger, G; Milano, G; Misset, JL; Touitou, Y	1
Goldschmidt, E; Grison, X; Guillot, T; Hannoun, L; Lotz, JP; Machover, D; Marquet, J; Metzger, G; Richaud, J; Zittoun, J	1
Bunni, MA; Priest, DG; Schmitz, JC	1
Dohden, K; Ohmura, K; Watanabe, Y	1
Adachi, I; Hashimoto, T; Ishida, F; Kawakami, K; Matsu, T; Omura, K; Watanabe, Y	1
Colditz, GA; Giovannucci, E; Rimm, EB; Rosner, BA; Speizer, FE; Stampfer, MJ; Trichopoulos, D; Willett, WC	1
Djavanmard, MP; Jakesz, R; Mader, RM; Rainer, H; Rizovski, B; Scheithauer, W; Steger, GG	1
Bovo, G; Bratina, G; Brenna, A; Brivio, F; Brivio, O; Fumagalli, L; Lavorato, F; Perego, P; Uggeri, F	1
Albanes, D; Barrett, MJ; Brown, CC; Glynn, SA; Gunter, EW; Pietinen, P; Rautalahti, M; Tangrea, JA; Taylor, PR; Virtamo, J	1
Choi, SW; James, SJ; Kim, YI; Mason, JB; Pogribny, IP; Salomon, RN; Smith, DE	1
Chen, J; Colditz, GA; Giovannucci, E; Hunter, DJ; Kelsey, K; Rimm, EB; Spiegelman, D; Stampfer, MJ; Willett, WC	1
Belghiti, C; Boutron-Ruault, MC; Couillault, C; Faivre, J; Senesse, P	1
Kupper, LL; Murray, SC; Sandler, RS; Tseng, M	1
Arezzini, L; Civitelli, S; Frosi, B; Marinello, E; Porcelli, B; Rosi, F; Tanzini, G	1
Levesque, T; Mason, JB	1
Brzezinski, A; Knesebeck, A; Lashner, BA; Provencher, KS; Seidner, DL	1
Artigas, C; Fuchs, C; Giovannucci, E; Hennekens, CH; Hunter, DJ; Ma, J; Rozen, R; Selhub, J; Stampfer, MJ; Willett, WC	1
Brienza, S; Cvitkovic, E; Raymond, E; Soulié, P	1
Baron, JA; Greenberg, ER; Haile, RW; Mandel, JS; Mott, LA; Sandler, RS	1
Geisler, J; Geisler, SB; Lønning, PE; Refsum, H; Smaaland, R; Tveit, KM; Ueland, PM	1
Scott, JM; Weir, DG	1
Koutroubakis, I; Mouzas, IA; Papavassiliou, E	1
Biasco, G; Zannoni, U	1
Chen, J; Giovannucci, E; Hankinson, SE; Hunter, DJ; Kelsey, KT; Ma, J; Spiegelman, D; Willett, WC	1
Chen, J; Giovannucci, EL; Hunter, DJ	1
Akhmedkhanov, A; Dnistrian, AM; Kato, I; Koenig, K; Riboli, E; Schwartz, M; Shore, RE; Toniolo, P; Zeleniuch-Jacquotte, A	1
Adamek, HE; Riemann, JF	1
Chen, J; Christensen, B; Giovannucci, E; Gravel, R; Hennekens, CH; Hunter, DJ; Ma, J; Rozen, R; Selhub, J; Stampfer, MJ; Willett, WC	1
Ahnen, DJ; Alberts, DS; Einspahr, J; Hamilton, SR; Maltzman, T; Marshall, JR; Martínez, ME; Reid, ME; Sampliner, R	1
Baik, HW; Choi, SW; Kim, YI; Mason, JB; Seitz, HK; Stickel, F	1
Choi, SW; Fung, L; Graeme-Cook, F; Kim, YI; Mason, JB; Medline, A; Puchyr, M; Salomon, RN; Sohn, KJ	1
Danenberg, PV; Malli, H; Swenson, S	1
Jeanteur, P	1
Little, J	1
Ash, C; Gallinger, S; Kim, YI; Medline, A; Sohn, KJ; Song, J	1
Jänne, PA; Mayer, RJ	1
Cassidy, J	1
Le Leu, RK; McIntosh, GH; Young, GP	1
Evensen, ET; Hoff, G; Lien, EA; Majak, BM; Ueland, PM; Ulvik, A; Vollset, SE	1
Freedman, AN; Ishibe, N	1
Gmeiner, WH; Kolar, C; Lawson, TA; Liu, J	1
Andersson, C; O'Brien, NM; Wild, CP; Wilson, L; Woods, JA	1
Ryan, BM; Weir, DG	1
Molloy, AM; Scott, JM	1
Fohr, I; Pietrzik, K; Prinz-Langenohl, R	1
Adler, G; Lutz, MP	1
Hawk, ET; Umar, A; Viner, JL	1
Gwyn, K; Sinicrope, FA	1
Howe, GR; Jain, M; Miller, AB; Rohan, TE; Terry, P	1
Ponz, D	1
Chen, J; Hunter, DJ; Ma, J; Palomeque, C; Selhub, J; Stampfer, MJ	1
Bigler, J; Bostick, R; Fosdick, L; Potter, JD; Ulrich, CM	1
Fairfield, KM; Fletcher, RH	1
Archili, C; Barni, S; Crispino, S; Lissoni, P; Paolorossi, F; Tancini, G	1

Reviews

113 review(s) available for folic acid and Colorectal Cancer

Article	Year
Folate intake and risk of colorectal cancer: a systematic review and up-to-date meta-analysis of prospective studies. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2023, 03-01, Volume: 32, Issue:2 Topics: Colonic Neoplasms; Colorectal Neoplasms; Diet; Folic Acid; Humans; Prospective Studies; Risk; Risk Factors	2023
Colon microbiota modulation by dairy-derived diet: new strategy for prevention and treatment of colorectal cancer. Food & function, 2022, Sep-22, Volume: 13, Issue:18 Topics: Butyrates; Calcium, Dietary; Colorectal Neoplasms; Diet; Fatty Acids, Volatile; Folic Acid; Gastrointestinal Microbiome; Humans; Propionates; Vitamin D	2022
Influence of methyl donor nutrients as epigenetic regulators in colorectal cancer: A systematic review of observational studies. World journal of gastroenterology, 2023, Feb-21, Volume: 29, Issue:7 Topics: Colorectal Neoplasms; CpG Islands; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans; Microsatellite Instability; Nutrients	2023
An overview of yeast probiotics as cancer biotherapeutics: possible clinical application in colorectal cancer. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:8 Topics: Antineoplastic Agents; beta-Glucans; Clinical Trials as Topic; Colorectal Neoplasms; Databases, Factual; Disease Progression; Folic Acid; Gastrointestinal Microbiome; Humans; Inflammation; MAP Kinase Signaling System; Probiotics; Saccharomyces boulardii; Saccharomyces cerevisiae; Signal Transduction; Yeasts	2020
Recent advances in clinical practice: colorectal cancer chemoprevention in the average-risk population. Gut, 2020, Volume: 69, Issue:12 Topics: Alcohol Drinking; Allium; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Caffeine; Coffee; Colorectal Neoplasms; Dairy Products; Dietary Fiber; Fatty Acids, Omega-3; Fish Products; Folic Acid; Fruit; Garlic; Glycine max; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnesium; Meat; Tea; Vegetables; Vitamins	2020
Functional Foods in the Prevention of Colorectal Cancer. Critical reviews in oncogenesis, 2020, Volume: 25, Issue:2 Topics: Colorectal Neoplasms; Curcumin; Folic Acid; Functional Food; Garlic; Humans; Signal Transduction	2020
Metastatic colorectal cancer: Advances in the folate-fluoropyrimidine chemotherapy backbone. Cancer treatment reviews, 2021, Volume: 98 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Fluorouracil; Folic Acid; Humans; Irinotecan; Leucovorin; Oxaliplatin; Prognosis	2021
Folic acid intake and folate status and colorectal cancer risk: A systematic review and meta-analysis. Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:6 Pt A Topics: Biological Availability; Case-Control Studies; Colorectal Neoplasms; Diet; Dietary Supplements; Folic Acid; Humans; Nutritional Status; Odds Ratio; Randomized Controlled Trials as Topic; Risk Factors	2018
Bacterial folate biosynthesis and colorectal cancer risk: more than just a gut feeling. Critical reviews in food science and nutrition, 2020, Volume: 60, Issue:2 Topics: Bacteria; Colorectal Neoplasms; Diet; Folic Acid; Humans; Vitamin B Complex	2020
Energy balance related lifestyle factors and risk of endometrial and colorectal cancer among individuals with lynch syndrome: a systematic review. Familial cancer, 2019, Volume: 18, Issue:4 Topics: Body Weight; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Endometrial Neoplasms; Energy Intake; Energy Metabolism; Exercise; Feeding Behavior; Female; Folic Acid; Humans; Life Style; Male; Vitamins	2019
Colorectal cancer in inflammatory bowel disease: results of the 3rd ECCO pathogenesis scientific workshop (I). Journal of Crohn's & colitis, 2014, Volume: 8, Issue:1 Topics: Age of Onset; Anticarcinogenic Agents; Cholangitis, Sclerosing; Colitis, Ulcerative; Colorectal Neoplasms; Congresses as Topic; Crohn Disease; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunologic Factors; Mesalamine; Risk Factors; Survival Rate; Time Factors; Ursodeoxycholic Acid	2014
Quantifying the dose-response relationship between circulating folate concentrations and colorectal cancer in cohort studies: a meta-analysis based on a flexible meta-regression model. American journal of epidemiology, 2013, Oct-01, Volume: 178, Issue:7 Topics: Cohort Studies; Colorectal Neoplasms; Dose-Response Relationship, Drug; Epidemiologic Studies; Folic Acid; Humans; Risk Assessment; Risk Factors	2013
Pharmacological and dietary prevention for colorectal cancer. BMC surgery, 2013, Volume: 13 Suppl 2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Calcium; Colorectal Neoplasms; Diet; Folic Acid; Humans; Micronutrients; Probiotics	2013
Folate-related nutrients, genetic polymorphisms, and colorectal cancer risk: the fukuoka colorectal cancer study. Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:11 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Alleles; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Food; Genotype; Humans; Japan; Male; Methionine; Middle Aged; Polymorphism, Genetic; Risk; Thymidylate Synthase; Vitamins; Young Adult	2013
[Chemoprevention of colorectal cancer in inflammatory bowel disease]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2014, Jan-25, Volume: 63, Issue:1 Topics: Anti-Inflammatory Agents; Chemoprevention; Colorectal Neoplasms; Folic Acid; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mesalamine; Ursodeoxycholic Acid	2014
How folate metabolism affects colorectal cancer development and treatment; a story of heterogeneity and pleiotropy. Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt A Topics: Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Genetic Heterogeneity; Genetic Pleiotropy; Genetic Variation; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Thymidylate Synthase	2015
The effect of diet on the intestinal epigenome. Epigenomics, 2014, Volume: 6, Issue:2 Topics: Animals; Colorectal Neoplasms; CpG Islands; Diet; Dietary Fiber; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Histone Deacetylases; Humans; Intestinal Mucosa; Intestines; Mice; Nutritional Status; Rats	2014
Folic acid supplements and colorectal cancer risk: meta-analysis of randomized controlled trials. Scientific reports, 2015, Jul-01, Volume: 5 Topics: Anticarcinogenic Agents; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Randomized Controlled Trials as Topic; Risk	2015
The effects of nutritional interventions on recurrence in survivors of colorectal adenomas and cancer: a systematic review of randomised controlled trials. European journal of clinical nutrition, 2016, Volume: 70, Issue:5 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Antioxidants; Cancer Survivors; Colorectal Neoplasms; Dietary Supplements; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nutrition Therapy; Randomized Controlled Trials as Topic; Time; Treatment Outcome	2016
Folic Acid Supplementation May Reduce Colorectal Cancer Risk in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. Journal of clinical gastroenterology, 2017, Volume: 51, Issue:3 Topics: Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Inflammatory Bowel Diseases; Risk Factors	2017
Folate status and colorectal cancer risk: A 2016 update. Molecular aspects of medicine, 2017, Volume: 53 Topics: Colorectal Neoplasms; Folic Acid; Humans; Risk Factors	2017
Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis. BMJ (Clinical research ed.), 2016, Dec-05, Volume: 355 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bayes Theorem; Calcium; Chemoprevention; Colorectal Neoplasms; Folic Acid; Humans; Network Meta-Analysis; Vitamin B Complex; Vitamin D; Vitamins	2016
[Folic acid and prevention of neural tube closure defects: the question is not solved yet]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2008, Volume: 15, Issue:7 Topics: Adult; Aged; Animals; Breast Neoplasms; Clinical Trials as Topic; Cognition Disorders; Cohort Studies; Colorectal Neoplasms; Edible Grain; Female; Folic Acid; Food, Fortified; France; Humans; Infant, Newborn; Male; Middle Aged; Neural Tube Defects; Pregnancy; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Spinal Dysraphism; United States	2008
Other one-carbon micronutrients and age modulate the effects of folate on colorectal carcinogenesis. Nutrition reviews, 2008, Volume: 66 Suppl 1 Topics: Aging; Animals; Colorectal Neoplasms; Diet; DNA Methylation; Folic Acid; Humans; Micronutrients; Risk Factors; Vitamin B Complex; Wnt Proteins	2008
Folic acid supplementation and cancer risk: point. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:9 Topics: Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Folic Acid; Humans; Neoplasm Recurrence, Local; Neoplasms; Primary Prevention	2008
Folate and cancer prevention--where to next? Counterpoint. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:9 Topics: Cell Transformation, Neoplastic; Colorectal Neoplasms; Folic Acid; Genetic Variation; Humans; Neoplasms; Prognosis	2008
Too much folate: a risk factor for cancer and cardiovascular disease? Current opinion in clinical nutrition and metabolic care, 2009, Volume: 12, Issue:1 Topics: Adenoma; Cardiovascular Diseases; Chronic Disease; Colorectal Neoplasms; Dietary Supplements; Dose-Response Relationship, Drug; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Neoplasms; Risk Factors	2009
Folate and colorectal cancer prevention. British journal of cancer, 2009, Jan-27, Volume: 100, Issue:2 Topics: Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Randomized Controlled Trials as Topic; Vitamin B Complex	2009
Diet and cancer prevention: the roles of observation and experimentation. Nature reviews. Cancer, 2008, Volume: 8, Issue:9 Topics: Colorectal Neoplasms; Diet; Dietary Supplements; Empirical Research; Folic Acid; Humans; Randomized Controlled Trials as Topic; Research Design	2008
Folate, cancer risk, and the Greek god, Proteus: a tale of two chameleons. Nutrition reviews, 2009, Volume: 67, Issue:4 Topics: Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Risk Factors; Vitamin B Complex	2009
Development of dietary phytochemical chemopreventive agents: biomarkers and choice of dose for early clinical trials. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:6 Topics: Animals; Anticarcinogenic Agents; beta Carotene; Biomarkers; Cell Line, Tumor; Clinical Trials as Topic; Colorectal Neoplasms; Diet; DNA Adducts; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; Folic Acid; Genistein; Humans; Lung Neoplasms; Male; Plant Extracts; Plants, Edible; Rats	2009
[Chemoprevention of colorectal cancer]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2009, Volume: 26, Issue:155 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cholecalciferol; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Folic Acid; Gastrointestinal Diseases; Humans; Risk Assessment	2009
Folic acid supplementation for the prevention of recurrence of colorectal adenomas: metaanalysis of interventional trials. Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:3 Topics: Adenocarcinoma; Adenomatous Polyps; Colonic Polyps; Colorectal Neoplasms; Dose-Response Relationship, Drug; Folic Acid; Humans; Intestinal Polyps; Randomized Controlled Trials as Topic; Recurrence; Research Design; Treatment Failure	2010
Folic acid supplementation and colorectal cancer risk: a meta-analysis. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2011, Volume: 13, Issue:2 Topics: Adenoma; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Time Factors	2011
Meta-analysis: folic acid in the chemoprevention of colorectal adenomas and colorectal cancer. Alimentary pharmacology & therapeutics, 2010, Volume: 31, Issue:7 Topics: Adenoma; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Folic Acid; Humans; Randomized Controlled Trials as Topic	2010
Folate and fiber in the prevention of colorectal cancer: between shadows and the light. World journal of gastroenterology, 2010, Feb-28, Volume: 16, Issue:8 Topics: Chemoprevention; Colorectal Neoplasms; Dietary Fiber; Folic Acid; Humans; Risk Factors	2010
Chemoprevention of colorectal cancer: systematic review and economic evaluation. Health technology assessment (Winchester, England), 2010, Volume: 14, Issue:32 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; beta Carotene; Calcium; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Cyclooxygenase 2 Inhibitors; Folic Acid; Humans; Incidence; Models, Economic; Prognosis; Risk Assessment; Selenium; United Kingdom	2010
Time course of risk factors in cancer etiology and progression. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Sep-10, Volume: 28, Issue:26 Topics: Alcohol Drinking; Breast Neoplasms; Colorectal Neoplasms; Diet; Disease Progression; Female; Folic Acid; Humans; Lung Neoplasms; Male; Neoplasms; Prognosis; Prostatic Neoplasms; Risk Factors; Smoking	2010
Pooled analyses of 13 prospective cohort studies on folate intake and colon cancer. Cancer causes & control : CCC, 2010, Volume: 21, Issue:11 Topics: Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Confidence Intervals; Diet; Female; Folic Acid; Humans; Incidence; Male; Proportional Hazards Models; Prospective Studies; Risk	2010
Use of pathway information in molecular epidemiology. Human genomics, 2009, Volume: 4, Issue:1 Topics: Bayes Theorem; Colorectal Neoplasms; Epistasis, Genetic; Folic Acid; Genetic Markers; Genome-Wide Association Study; Genotype; Humans; Metabolic Networks and Pathways; Molecular Epidemiology; Polymorphism, Genetic; Risk	2009
Folate intake and the risk of colorectal cancer: a systematic review and meta-analysis. Cancer epidemiology, 2011, Volume: 35, Issue:1 Topics: Clinical Trials as Topic; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Incidence; Risk Factors; Vitamin B Complex	2011
Folic acid in obstetric practice: a review. Obstetrical & gynecological survey, 2011, Volume: 66, Issue:4 Topics: Adenoma; Animals; Colorectal Neoplasms; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Humans; Neural Tube Defects; Pregnancy; Prenatal Care	2011
The impact of folate status on the efficacy of colorectal cancer treatment. Current drug metabolism, 2011, Volume: 12, Issue:10 Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Colorectal Neoplasms; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Genotype; Humans; Intestinal Absorption; Methylenetetrahydrofolate Reductase (NADPH2); Treatment Outcome	2011
Chemoprevention of colorectal cancer: a role for ursodeoxycholic acid, folate and hormone replacement treatment? Best practice & research. Clinical gastroenterology, 2011, Volume: 25, Issue:4-5 Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Colorectal Neoplasms; Estrogen Replacement Therapy; Folic Acid; Humans; Treatment Outcome; Ursodeoxycholic Acid	2011
Epigenetic biomarkers of colorectal cancer: Focus on DNA methylation. Cancer letters, 2014, Jan-28, Volume: 342, Issue:2 Topics: Animals; Biomarkers, Tumor; Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genetic Testing; Humans; Phenotype; Predictive Value of Tests; Pregnancy; Prenatal Care; Prenatal Exposure Delayed Effects; Prognosis; Risk Factors; Vitamin B Complex	2014
[Genetics and epigenetics of colorectal cancer]. Acta gastroenterologica Latinoamericana, 2011, Volume: 41, Issue:3 Topics: Adenomatous Polyposis Coli; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Cyclin-Dependent Kinase Inhibitor p57; Epigenesis, Genetic; Folic Acid; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Lymphoid Enhancer-Binding Factor 1; Mutation	2011
Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role. Advances in nutrition (Bethesda, Md.), 2012, Volume: 3, Issue:1 Topics: Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Humans; Neoplasms	2012
Functional polymorphisms of folate metabolism and response to chemotherapy for colorectal cancer, a systematic review and meta-analysis. Pharmacogenetics and genomics, 2012, Volume: 22, Issue:4 Topics: Capecitabine; Colorectal Neoplasms; Databases, Genetic; Deoxycytidine; Fluorouracil; Folic Acid; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Genetic Variation; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Tetrahydrofolate Dehydrogenase; Thymidylate Synthase	2012
MTHFR C677T polymorphism and colorectal cancer risk in Asians, a meta-analysis of 21 studies. Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:4 Topics: Alleles; Asian People; Colorectal Neoplasms; Confidence Intervals; Diet; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide	2012
Folate, colorectal cancer and the involvement of DNA methylation. The Proceedings of the Nutrition Society, 2012, Volume: 71, Issue:4 Topics: Animals; Colon; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; Folic Acid; Humans; Methionine; Vitamin B Complex	2012
The complexities of epidemiology and prevention of gastrointestinal cancers. International journal of molecular sciences, 2012, Oct-01, Volume: 13, Issue:10 Topics: Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Diabetes Complications; Folic Acid; Gastrointestinal Neoplasms; Humans; Hypoglycemic Agents; Inflammatory Bowel Diseases; Metformin; Obesity; Pancreatic Neoplasms; Smoking	2012
Strong correlation between diet and development of colorectal cancer. Frontiers in bioscience (Landmark edition), 2013, 01-01, Volume: 18, Issue:1 Topics: Alcohol Drinking; Colitis; Colorectal Neoplasms; Diet; Dietary Fiber; Epigenesis, Genetic; Fatty Acids, Unsaturated; Folic Acid; Fruit; Glycemic Index; Humans; Insulin Resistance; Intestinal Mucosa; Meat; Obesity; Smoking; Vegetables	2013
A meta-analysis of the C1420T polymorphism in cytosolic serine hydroxymethyltransferase (SHMT1) among Caucasian colorectal cancer populations. International journal of colorectal disease, 2013, Volume: 28, Issue:7 Topics: Colorectal Neoplasms; Cytosol; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Polymorphism, Single Nucleotide; Publication Bias; White People	2013
Folate-genetics and colorectal neoplasia: what we know and need to know next. Molecular nutrition & food research, 2013, Volume: 57, Issue:4 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Colorectal Neoplasms; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Meta-Analysis as Topic; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Randomized Controlled Trials as Topic; Risk Factors; S-Adenosylmethionine; Thymidylate Synthase	2013
Epidemiologic studies of folate and colorectal neoplasia: a review. The Journal of nutrition, 2002, Volume: 132, Issue:8 Suppl Topics: Colorectal Neoplasms; Diet; Female; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Humans; Male; Methionine; Risk Factors	2002
Folate status: effects on pathways of colorectal carcinogenesis. The Journal of nutrition, 2002, Volume: 132, Issue:8 Suppl Topics: Cell Transformation, Neoplastic; Colorectal Neoplasms; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors	2002
Dairy products and colorectal cancer. A review of possible mechanisms and epidemiological evidence. European journal of clinical nutrition, 2003, Volume: 57, Issue:1 Topics: Animals; Calcium, Dietary; Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Dairy Products; Dietary Fats; Female; Fermentation; Folic Acid; Humans; Male; Milk Proteins; Somatomedins; Vitamin D; Yogurt	2003
[Colorectal cancer and folate]. Zeitschrift fur Gastroenterologie, 2003, Volume: 41, Issue:3 Topics: Colorectal Neoplasms; DNA Damage; DNA Methylation; Epidemiologic Studies; Feeding Behavior; Folic Acid; Genetic Predisposition to Disease; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors	2003
Chemoprevention of colorectal cancer: slow, steady progress. Cleveland Clinic journal of medicine, 2003, Volume: 70, Issue:4 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Celecoxib; Colorectal Neoplasms; Folic Acid; Humans; Pyrazoles; Sulfonamides; Sulindac	2003
Diet, body weight, and colorectal cancer: a summary of the epidemiologic evidence. Journal of women's health (2002), 2003, Volume: 12, Issue:2 Topics: Calcium; Colorectal Neoplasms; Feeding Behavior; Folic Acid; Humans; Obesity; Risk Factors; United States	2003
Relationship of folate to colorectal and cervical cancer: review and recommendations for practitioners. Journal of the American Dietetic Association, 2002, Volume: 102, Issue:9 Topics: Colorectal Neoplasms; Confidence Intervals; DNA Damage; DNA Methylation; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Odds Ratio; Risk Factors; Uterine Cervical Neoplasms	2002
Chemoprevention of colorectal cancer in ulcerative colitis. International journal of colorectal disease, 2003, Volume: 18, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium, Dietary; Chemoprevention; Cholagogues and Choleretics; Colitis, Ulcerative; Colorectal Neoplasms; Folic Acid; Hematinics; Humans; Mesalamine; Ursodeoxycholic Acid	2003
Folate, DNA methylation and colo-rectal cancer. The Proceedings of the Nutrition Society, 2003, Volume: 62, Issue:2 Topics: Adenoma; Animals; Anticarcinogenic Agents; Colorectal Neoplasms; DNA Methylation; Dose-Response Relationship, Drug; Folic Acid; Humans; Polymorphism, Genetic; Risk Factors	2003
Review article: chemoprevention of colorectal cancer. Alimentary pharmacology & therapeutics, 2004, Jan-01, Volume: 19, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Dietary Fiber; Eflornithine; ErbB Receptors; Folic Acid; Humans; Life Expectancy; Mass Screening; Selenium; Ursodeoxycholic Acid	2004
Folic acid and sulfasalazine for colorectal carcinoma chemoprevention in patients with ulcerative colitis: the old and new evidence. Romanian journal of gastroenterology, 2003, Volume: 12, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colorectal Neoplasms; Drug Therapy, Combination; Folic Acid; Humans; Risk Factors; Sulfasalazine	2003
Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. American journal of epidemiology, 2004, Mar-01, Volume: 159, Issue:5 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Colorectal Neoplasms; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors	2004
Folate, colorectal carcinogenesis, and DNA methylation: lessons from animal studies. Environmental and molecular mutagenesis, 2004, Volume: 44, Issue:1 Topics: Animals; Anticarcinogenic Agents; Colorectal Neoplasms; Diet; Disease Models, Animal; DNA Methylation; DNA Replication; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Humans; Models, Biological; Time Factors	2004
Chemopreventive role of folic acid in colorectal cancer. Frontiers in bioscience : a journal and virtual library, 2004, Sep-01, Volume: 9 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; CpG Islands; DCC Receptor; DNA Methylation; ErbB Receptors; Folic Acid; Humans; Loss of Heterozygosity; Receptors, Cell Surface; Tumor Suppressor Proteins	2004
[Methylenetetrahydrofolate reductase polymorphisms and colorectal cancer risk: a human genomic epidemiologic review]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2004, Volume: 33, Issue:5 Topics: China; Colorectal Neoplasms; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Incidence; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors	2004
[Adjuvant and palliative anticancer treatment of colon carcinoma in 2004]. Praxis, 2004, Sep-29, Volume: 93, Issue:40 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Cetuximab; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Colon; Colonic Neoplasms; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Folic Acid; Humans; Leucovorin; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Palliative Care; Postoperative Care; Randomized Controlled Trials as Topic; Time Factors	2004
Folate intake and colorectal cancer risk: a meta-analytical approach. International journal of cancer, 2005, Feb-20, Volume: 113, Issue:5 Topics: Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Risk Factors	2005
[Pharmacological capacities of the prevention of colorectal cancer]. Klinicheskaia meditsina, 2004, Volume: 82, Issue:11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Calcium; Colorectal Neoplasms; Dietary Fiber; Feeding Behavior; Folic Acid; Humans; Resveratrol; Stilbenes	2004
Colorectal cancer prevention: is an ounce of prevention worth a pound of cure? Seminars in oncology, 2005, Volume: 32, Issue:1 Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Calcium; Clinical Trials as Topic; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Eflornithine; Folic Acid; Humans; Intestinal Mucosa; Selenium; Ursodeoxycholic Acid	2005
Folate, DNA stability and colo-rectal neoplasia. The Proceedings of the Nutrition Society, 2004, Volume: 63, Issue:4 Topics: Carbon-Nitrogen Ligases; Colorectal Neoplasms; DNA Damage; DNA Methylation; DNA Repair; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Humans; Polymorphism, Genetic; Proto-Oncogene Mas; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency	2004
Folic acid and colorectal cancer prevention: molecular mechanisms and epidemiological evidence (Review). International journal of oncology, 2005, Volume: 26, Issue:6 Topics: Adenoma; Colorectal Neoplasms; DNA Methylation; ErbB Receptors; Folic Acid; Humans	2005
Folate and its preventive potential in colorectal carcinogenesis. How strong is the biological and epidemiological evidence? Critical reviews in oncology/hematology, 2005, Volume: 55, Issue:1 Topics: Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Evidence-Based Medicine; Folic Acid; Folic Acid Deficiency; Humans; Treatment Outcome	2005
Folate and prevention of colorectal cancer in ulcerative colitis. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2005, Volume: 14, Issue:4 Topics: Adult; Age Distribution; Aged; Chemoprevention; Colitis, Ulcerative; Colonoscopy; Colorectal Neoplasms; Female; Folic Acid; Humans; Incidence; Italy; Male; Middle Aged; Precancerous Conditions; Risk Assessment; Sex Distribution; Survival Rate	2005
Genetic polymorphisms of methylenetetrahydrofolate reductase and colorectal cancer and adenoma. Cancer science, 2005, Volume: 96, Issue:9 Topics: Adenoma; Colorectal Neoplasms; Epidemiologic Studies; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Polymorphism, Genetic	2005
Interaction among folate, riboflavin, genotype, and cancer, with reference to colorectal and cervical cancer. The Journal of nutrition, 2005, Volume: 135, Issue:12 Suppl Topics: Colorectal Neoplasms; Drug Interactions; Female; Folic Acid; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Papillomavirus Infections; Riboflavin; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms	2005
The fibre-folate debate in colo-rectal cancer. The Proceedings of the Nutrition Society, 2006, Volume: 65, Issue:1 Topics: Colorectal Neoplasms; Confounding Factors, Epidemiologic; Dietary Fiber; Evidence-Based Medicine; Folic Acid; Humans; Prospective Studies; Vitamin B Complex	2006
[Irinotecan for the treatment of metastatic colorectal cancer]. Bulletin du cancer, 2006, Volume: 93, Issue:5 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Folic Acid; Humans; Irinotecan; Maximum Tolerated Dose; Multicenter Studies as Topic; Pharmacogenetics	2006
Chemoprevention for colon cancer: new opportunities, fact or fiction? Scandinavian journal of gastroenterology. Supplement, 2006, Issue:243 Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Neoplasms; Colorectal Neoplasms; Europe; Folic Acid; Humans; Inflammatory Bowel Diseases; Population Surveillance; Risk Factors; Sex Factors	2006
Methyl-group metabolism and the response of colorectal cancer to 5-fluorouracil. Critical reviews in oncogenesis, 2006, Volume: 12, Issue:1-2 Topics: Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); DNA Methylation; Fluorouracil; Folic Acid; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Microsatellite Repeats; Thymidylate Synthase	2006
Chemoprophylaxis of colorectal cancer in inflammatory bowel disease: current concepts. Inflammatory bowel diseases, 2007, Volume: 13, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholagogues and Choleretics; Colorectal Neoplasms; Folic Acid; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine; Treatment Outcome; Ursodeoxycholic Acid; Vitamin B Complex	2007
Folate in colorectal cancer, prostate cancer and cardiovascular disease. Scandinavian journal of clinical and laboratory investigation, 2007, Volume: 67, Issue:5 Topics: Colorectal Neoplasms; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Myocardial Infarction; Prostatic Neoplasms; Sweden; Vitamin B Complex	2007
Chemoprevention of colorectal cancer. Digestion, 2007, Volume: 76, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Calcium Compounds; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Dietary Fiber; Dietary Supplements; ErbB Receptors; Estrogen Replacement Therapy; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Selenium; Ursodeoxycholic Acid; Vitamin E	2007
Folic acid fortification and supplementation--good for some but not so good for others. Nutrition reviews, 2007, Volume: 65, Issue:11 Topics: Animals; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Food, Fortified; Humans; Neural Tube Defects; Nutrition Policy; Nutritional Sciences; Risk Factors	2007
Food fortification with folic acid: has the other shoe dropped? Nutrition reviews, 2007, Volume: 65, Issue:11 Topics: Colorectal Neoplasms; Dietary Supplements; Folic Acid; Food, Fortified; Humans; Neural Tube Defects; North America; Nutrition Policy; Nutritional Sciences; Vitamin B Complex	2007
Chemoprevention of colorectal cancer: why all the confusion? Current opinion in gastroenterology, 2008, Volume: 24, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium; Colorectal Neoplasms; Diet; Dietary Fiber; Dietary Supplements; Folic Acid; Humans; Randomized Controlled Trials as Topic	2008
[Colorectal cancer chemoprevention]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2007, Volume: 23, Issue:133 Topics: Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Calcium; Chemoprevention; Cholecalciferol; Colonoscopy; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Early Diagnosis; Folic Acid; Humans; Mass Screening; Randomized Controlled Trials as Topic; Rectal Neoplasms; SEER Program	2007
Folate metabolites as modulators of antitumor drug activity. Advances in experimental medicine and biology, 1993, Volume: 338 Topics: Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Biotransformation; Cell Line; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Leucovorin; Ovarian Neoplasms; Tetrahydrofolates; Tumor Cells, Cultured	1993
Folate: effects on carcinogenesis and the potential for cancer chemoprevention. Oncology (Williston Park, N.Y.), 1996, Volume: 10, Issue:11 Topics: Animals; Cell Transformation, Neoplastic; Chemoprevention; Clinical Trials as Topic; Colorectal Neoplasms; Female; Folic Acid; Folic Acid Deficiency; Humans; Uterine Cervical Neoplasms	1996
[Oxaliplatin: the first DACH platinum in clinical practice]. Bulletin du cancer, 1997, Volume: 84, Issue:6 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Male; Neoplasms; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Peripheral Nervous System Diseases; Survival Analysis	1997
Colonic mucosal folate concentrations and their association with colorectal cancer. The American journal of clinical nutrition, 1998, Volume: 68, Issue:4 Topics: Colon; Colorectal Neoplasms; Female; Folic Acid; Humans; Intestinal Mucosa; Male	1998
Chemoprevention of colorectal cancer in inflammatory bowel disease? A potential role for folate. Italian journal of gastroenterology and hepatology, 1998, Volume: 30, Issue:4 Topics: Colitis, Ulcerative; Colorectal Neoplasms; Crohn Disease; Folic Acid; Humans; Inflammatory Bowel Diseases; Risk Factors	1998
MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis. The Journal of nutrition, 1999, Volume: 129, Issue:2S Suppl Topics: Adenoma; Carcinoma; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors	1999
Thymidylate synthase inhibitors. Seminars in oncology, 1999, Volume: 26, Issue:6 Topics: Animals; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Indoles; Isoindoles; Pemetrexed; Quinazolines; Thiophenes; Thymidylate Synthase	1999
Problems and approaches in investigating the role of micronutrients in the aetiology of cancer in humans. British medical bulletin, 1999, Volume: 55, Issue:3 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Arylamine N-Acetyltransferase; Colorectal Neoplasms; Folic Acid; Genetic Predisposition to Disease; Hemochromatosis; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neoplasms; Oxidoreductases; Polymorphism, Genetic; Protective Agents; Research Design	1999
Chemoprevention of colorectal cancer. The New England journal of medicine, 2000, Jun-29, Volume: 342, Issue:26 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Calcium; Colorectal Neoplasms; Dietary Fiber; Folic Acid; Hormone Replacement Therapy; Humans; Vitamins	2000
Thymidylate synthase inhibitors in colorectal cancer. Seminars in oncology, 2000, Volume: 27, Issue:5 Suppl 10 Topics: Antineoplastic Agents; Clinical Trials as Topic; Colorectal Neoplasms; Enzyme Inhibitors; Folic Acid; Glutamates; Guanine; Humans; Pemetrexed; Quinazolines; Thiophenes; Thymidylate Synthase	2000
Understanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis. Cancer investigation, 2001, Volume: 19, Issue:5 Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p27; Dietary Fiber; Environmental Exposure; Enzyme Inhibitors; Folic Acid; Genes, APC; Genes, bcl-2; Genes, DCC; Genes, p53; Genes, ras; Genes, Tumor Suppressor; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Microtubule-Associated Proteins; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Smoking; Tumor Suppressor Proteins	2001
The mechanisms by which folate depletion enhances colorectal carcinogenesis: a unified scheme. Nestle Nutrition workshop series. Clinical & performance programme, 2000, Volume: 4 Topics: Animals; Colorectal Neoplasms; DNA Methylation; Folic Acid; Folic Acid Deficiency; Humans; Incidence; Methylenetetrahydrofolate Reductase (NADPH2); Nucleic Acids; Oxidoreductases Acting on CH-NH Group Donors	2000
A critical evaluation of the application of biomarkers in epidemiological studies on diet and health. The British journal of nutrition, 2001, Volume: 86 Suppl 1 Topics: Biomarkers; Colorectal Neoplasms; Cooking; Diet; Epidemiologic Factors; Estrogens, Non-Steroidal; Female; Folic Acid; Genetic Predisposition to Disease; Genistein; Health Surveys; Heterocyclic Compounds; Humans; Iodine; Isoflavones; Male; Meat; Middle Aged; Neural Tube Defects; Nutritional Status; Phytoestrogens; Plant Preparations; Predictive Value of Tests; Pregnancy; Prostatic Neoplasms; Risk Factors; Specimen Handling; Vitamin D	2001
Relevance of folate metabolism in the pathogenesis of colorectal cancer. The Journal of laboratory and clinical medicine, 2001, Volume: 138, Issue:3 Topics: Adenoma; Animals; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; DNA, Neoplasm; Folic Acid; Folic Acid Deficiency; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12	2001
Folates and prevention of disease. Public health nutrition, 2001, Volume: 4, Issue:2B Topics: Cardiovascular Diseases; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Food, Fortified; Homocysteine; Humans; Mental Disorders; Neural Tube Defects; Treatment Outcome	2001
Beneficial role for folate in the prevention of colorectal and breast cancer. European journal of nutrition, 2001, Volume: 40, Issue:3 Topics: Breast Neoplasms; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Methylation; Prospective Studies; Risk Factors	2001
[Chemotherapy of colorectal carcinoma]. Der Internist, 2001, Volume: 42, Issue:12 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Folic Acid; Humans; Irinotecan; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Survival Analysis; Treatment Outcome	2001
The future of colon cancer prevention. Annals of the New York Academy of Sciences, 2001, Volume: 952 Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Biomarkers; Calcium; Clinical Trials as Topic; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diagnostic Imaging; Disease Progression; Drug Design; Drug Synergism; Eflornithine; Enzyme Inhibitors; ErbB Receptors; Folic Acid; Forecasting; Genes, APC; Humans; Isoenzymes; Membrane Proteins; Mice; Models, Biological; Oligonucleotide Array Sequence Analysis; Ornithine Decarboxylase Inhibitors; Prostaglandin-Endoperoxide Synthases; Proteome; Risk	2001
Chemoprevention of colorectal cancer. The American journal of gastroenterology, 2002, Volume: 97, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; beta Carotene; Calcium Compounds; Colorectal Neoplasms; Dietary Fiber; Dietary Supplements; Eflornithine; Enzyme Inhibitors; Female; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Prognosis; Risk Assessment; Sensitivity and Specificity; Ursodeoxycholic Acid; Vitamin E	2002
[Chemoprevention of colorectal cancer]. Presse medicale (Paris, France : 1983), 2002, Jan-26, Volume: 31, Issue:3 Topics: Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arthritis, Rheumatoid; Aspirin; Calcium, Dietary; Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Controlled Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dietary Supplements; Eflornithine; Enzyme Inhibitors; Female; Folic Acid; Hormone Replacement Therapy; Humans; Male; Mice; Mice, Knockout; Middle Aged; Risk Factors; Sulindac; Time Factors; Vitamins	2002
Colorectal neoplasia and genetic polymorphisms associated with folate metabolism. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2002, Volume: 11, Issue:1 Topics: Animals; Antioxidants; Colorectal Neoplasms; Diet; Folic Acid; Humans; Polymorphism, Genetic; United States	2002
Prevention and chemoprevention of colorectal neoplasms. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2002, Volume: 34, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chemoprevention; Colorectal Neoplasms; Diet; Exercise; Folic Acid; Humans; Sulindac; Vitamins	2002
Vitamins for chronic disease prevention in adults: scientific review. JAMA, 2002, Jun-19, Volume: 287, Issue:23 Topics: Ascorbic Acid; Avitaminosis; Blood Coagulation; Breast Neoplasms; Carotenoids; Chronic Disease; Colorectal Neoplasms; Coronary Disease; Dietary Supplements; Female; Folic Acid; Fractures, Bone; Humans; Lung Neoplasms; Male; Neoplasms; Neural Tube Defects; Prostatic Neoplasms; Risk Factors; Vitamin A; Vitamin B 12; Vitamin B 6; Vitamin D; Vitamin E; Vitamin K; Vitamins	2002

Trials

52 trial(s) available for folic acid and Colorectal Cancer

Article	Year
Folic acid supplementation and risk of colorectal neoplasia during long-term follow-up of a randomized clinical trial. The American journal of clinical nutrition, 2019, 10-01, Volume: 110, Issue:4 Topics: Aged; Aspirin; Colorectal Neoplasms; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Humans; Male; Middle Aged; Time Factors	2019
Risk of basal cell carcinoma in a randomized clinical trial of aspirin and folic acid for the prevention of colorectal adenomas. The British journal of dermatology, 2018, Volume: 179, Issue:2 Topics: Adenoma; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Basal Cell; Colorectal Neoplasms; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Risk Assessment; Skin; Skin Neoplasms; Treatment Outcome	2018
Folic Acid and Vitamin B12 Supplementation and the Risk of Cancer: Long-term Follow-up of the B Vitamins for the Prevention of Osteoporotic Fractures (B-PROOF) Trial. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2019, Volume: 28, Issue:2 Topics: Aged; Aged, 80 and over; Colorectal Neoplasms; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Male; Neoplasms; Netherlands; Osteoporotic Fractures; Vitamin B 12	2019
Sequential Versus Combination Therapy of Metastatic Colorectal Cancer Using Fluoropyrimidines, Irinotecan, and Bevacizumab: A Randomized, Controlled Study-XELAVIRI (AIO KRK0110). Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 01-01, Volume: 37, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Folic Acid; Humans; Irinotecan; Leucovorin; Male	2019
Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients With Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 06-10, Volume: 37, Issue:17 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carbamates; Cetuximab; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Irinotecan; Male; Middle Aged; Mutation; Progression-Free Survival; Proto-Oncogene Proteins B-raf; Sulfonamides; Survival Rate	2019
Total circulating cell-free DNA as a prognostic biomarker in metastatic colorectal cancer before first-line oxaliplatin-based chemotherapy. Annals of oncology : official journal of the European Society for Medical Oncology, 2019, 07-01, Volume: 30, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell-Free Nucleic Acids; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Oxaliplatin; Prognosis; Prospective Studies; Retrospective Studies; Survival Rate	2019
The influence of folate supplementation on global gene expression in normal colonic mucosa of subjects with colorectal adenoma. Molecular nutrition & food research, 2013, Volume: 57, Issue:4 Topics: Aged; Cell Division; Colon; Colorectal Neoplasms; Dietary Supplements; Down-Regulation; Female; Folic Acid; Gene Expression; Humans; Intestinal Mucosa; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Up-Regulation	2013
Folic acid prevents the initial occurrence of sporadic colorectal adenoma in Chinese older than 50 years of age: a randomized clinical trial. Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:7 Topics: Adenoma; Case-Control Studies; Colonoscopy; Colorectal Neoplasms; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Prospective Studies; Risk Factors; Vitamin B Complex	2013
Reduction in γ-glutamyl hydrolase expression is associated with response to uracil and tegafur/leucovorin chemotherapy in patients with colorectal cancer. Anticancer research, 2013, Volume: 33, Issue:8 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Folic Acid; gamma-Glutamyl Hydrolase; Gene Expression Regulation, Neoplastic; Humans; Leucovorin; Male; Middle Aged; Tegafur; Treatment Outcome; Uracil	2013
The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia. The American journal of clinical nutrition, 2013, Volume: 98, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Colon; Colorectal Neoplasms; Cross-Sectional Studies; Diet; DNA Methylation; Folic Acid; Folic Acid Deficiency; Genetic Association Studies; Humans; Intestinal Mucosa; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Status; Polymorphism, Single Nucleotide; Risk; United Kingdom; Young Adult	2013
Genetic and environmental risk assessment and colorectal cancer screening in an average-risk population: a randomized trial. Annals of internal medicine, 2014, Oct-21, Volume: 161, Issue:8 Topics: Aged; Colorectal Neoplasms; Early Detection of Cancer; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Testing; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Patient Compliance; Polymorphism, Genetic; Precision Medicine; Risk; Risk Assessment	2014
Urinary metabolites of prostanoids and risk of recurrent colorectal adenomas in the Aspirin/Folate Polyp Prevention Study (AFPPS). Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:11 Topics: Adenoma; Administration, Oral; Aged; Aspirin; Chromatography, Gas; Chromatography, Liquid; Colonoscopy; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Humans; Male; Mass Spectrometry; Middle Aged; Neoplasm Recurrence, Local; Poisson Distribution; Prostaglandins	2015
Alcohol consumption, genetic variants in the alcohol- and folate metabolic pathways and colorectal cancer risk: the JPHC Study. Scientific reports, 2016, 11-09, Volume: 6 Topics: Adult; Aged; Alcohol Drinking; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Proteins; Polymorphism, Genetic; Prospective Studies; Registries; Risk Factors	2016
Folic acid supplementation inhibits recurrence of colorectal adenomas: a randomized chemoprevention trial. World journal of gastroenterology, 2008, Jul-28, Volume: 14, Issue:28 Topics: Adenoma; Aged; Colonoscopy; Colorectal Neoplasms; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Longitudinal Studies; Male; Middle Aged; Neoplasm Recurrence, Local; Risk Factors; Treatment Outcome	2008
Vitamins B2, B6, and B12 and risk of new colorectal adenomas in a randomized trial of aspirin use and folic acid supplementation. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:8 Topics: Adenoma; Alcohol Drinking; Aspirin; Chemoprevention; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Genotype; Humans; Incidence; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Poisson Distribution; Polymorphism, Genetic; Riboflavin; Risk; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6	2008
MTHFR genotype and colorectal adenoma recurrence: data from a double-blind placebo-controlled clinical trial. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:9 Topics: Adenoma; Alleles; Aspirin; Chi-Square Distribution; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Genotype; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Placebos; Polymorphism, Genetic	2008
Colorectal adenomas in a randomized folate trial: the role of baseline dietary and circulating folate levels. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:10 Topics: Adenoma; Aspirin; Colonoscopy; Colorectal Neoplasms; Confidence Intervals; Diet; Female; Folic Acid; Humans; Incidence; Linear Models; Male; Middle Aged; Placebos; Poisson Distribution; Risk Factors; Surveys and Questionnaires	2008
One-carbon metabolism biomarkers and risk of colon and rectal cancers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:11 Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Chi-Square Distribution; Colorectal Neoplasms; Double-Blind Method; Finland; Folic Acid; Humans; Logistic Models; Male; Middle Aged; Placebos; Primary Prevention; Risk; Risk Factors; Vitamin B 6	2008
Folic acid and risk of prostate cancer: results from a randomized clinical trial. Journal of the National Cancer Institute, 2009, Mar-18, Volume: 101, Issue:6 Topics: Adenoma; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Dietary Supplements; Double-Blind Method; Folic Acid; Follow-Up Studies; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Prostatic Neoplasms; Research Design; Surveys and Questionnaires; United States; Vitamin B Complex	2009
Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:4 Topics: Adenoma; Alcohol Drinking; Aspirin; Colon; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; CpG Islands; Diet; Dietary Supplements; DNA Methylation; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Life Style; Long Interspersed Nucleotide Elements; Male; Middle Aged; Phenotype; Prospective Studies; Risk Factors; Smoking; Vitamin B 6	2009
Cost-effectiveness analysis of XELOX for metastatic colorectal cancer based on the NO16966 and NO16967 trials. British journal of cancer, 2009, Jul-07, Volume: 101, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Cost-Benefit Analysis; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Folic Acid; Health Care Costs; Humans; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Quality of Life; Retrospective Studies; Treatment Outcome	2009
Molecular determinants of folate levels after leucovorin administration in colorectal cancer. Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:4 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Cluster Analysis; Colorectal Neoplasms; Drug Administration Schedule; Female; Folic Acid; gamma-Glutamyl Hydrolase; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Leucovorin; Logistic Models; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Peptide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Vitamin B Complex	2010
Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trial. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:10 Topics: Adenoma; Aged; Aspirin; Cohort Studies; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Folic Acid; Gene Frequency; Genetic Variation; Genotype; Haplotypes; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk Assessment	2009
A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma. The American journal of clinical nutrition, 2009, Volume: 90, Issue:6 Topics: Adenoma; Aged; Colorectal Neoplasms; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies	2009
A randomized trial of genetic and environmental risk assessment (GERA) for colorectal cancer risk in primary care: trial design and baseline findings. Contemporary clinical trials, 2011, Volume: 32, Issue:1 Topics: Age Factors; Aged; Colorectal Neoplasms; Early Detection of Cancer; Environmental Exposure; Female; Folic Acid; Genetic Counseling; Genetic Testing; Humans; Male; Middle Aged; Patient Acceptance of Health Care; Patient Participation; Polymorphism, Genetic; Primary Health Care; Risk Assessment	2011
Baseline plasma total homocysteine and adenoma recurrence: results from a double blind randomized clinical trial of aspirin and folate supplementation. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:10 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aspirin; Colorectal Neoplasms; Double-Blind Method; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Surveys and Questionnaires; Young Adult	2010
Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:12 Topics: Adenoma; Biomarkers, Tumor; Colon; Colonic Polyps; Colorectal Neoplasms; CpG Islands; DNA Methylation; Double-Blind Method; Estrogen Receptor alpha; Female; Folic Acid; Follow-Up Studies; Humans; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Male; Membrane Proteins; Middle Aged; Placebos; Prognosis; Rectum	2010
Altered folate availability modifies the molecular environment of the human colorectum: implications for colorectal carcinogenesis. Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:4 Topics: Adult; Aged; Biological Availability; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Dietary Supplements; DNA Breaks; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gene Expression; Gene Expression Profiling; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Rectum; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53	2011
Associations between genes in the one-carbon metabolism pathway and advanced colorectal adenoma risk in individuals with low folate intake. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012, Volume: 21, Issue:3 Topics: Adenoma; Aged; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Gene Expression Profiling; Genotype; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; One-Carbon Group Transferases; Polymorphism, Single Nucleotide; Prognosis; Risk Factors	2012
Effect of combined folic acid, vitamin B(6), and vitamin B(12) on colorectal adenoma. Journal of the National Cancer Institute, 2012, Oct-17, Volume: 104, Issue:20 Topics: Adenoma; Adult; Aged; Anticarcinogenic Agents; Cardiovascular Diseases; Colorectal Neoplasms; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Linear Models; Male; Middle Aged; Poisson Distribution; Risk Assessment; Risk Factors; Vitamin B 12; Vitamin B 6	2012
Short-term folate supplementation in physiological doses has no effect on ESR1 and MLH1 methylation in colonic mucosa of individuals with adenoma. Journal of nutrigenetics and nutrigenomics, 2012, Volume: 5, Issue:6 Topics: Adaptor Proteins, Signal Transducing; Adenoma; Aged; Colon; Colorectal Neoplasms; DNA Methylation; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Estrogen Receptor alpha; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Male; Middle Aged; MutL Protein Homolog 1; Nuclear Proteins; Placebos; Time Factors	2012
Chronomodulated chemotherapy in metastatic gastrointestinal cancer combining 5-FU and sodium folinate with oxaliplatin, irinotecan or gemcitabine: the Jena experience in 79 patients. Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Camptothecin; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Folic Acid; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Stomach Neoplasms	2002
Skin testing and hypersensitivity reactions to oxaliplatin. Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:3 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Drug Hypersensitivity; Female; Fluorouracil; Folic Acid; Humans; Injections, Intradermal; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Predictive Value of Tests; Skin Tests	2003
Folic acid mediated attenuation of loss of heterozygosity of DCC tumor suppressor gene in the colonic mucosa of patients with colorectal adenomas. Cancer detection and prevention, 2003, Volume: 27, Issue:4 Topics: Adenoma; Adenomatous Polyposis Coli Protein; Administration, Oral; Aged; Cell Adhesion Molecules; Cell Division; Colorectal Neoplasms; DCC Receptor; DNA, Neoplasm; Double-Blind Method; Female; Folic Acid; Genes, p53; Hematinics; Humans; Intestinal Mucosa; Loss of Heterozygosity; Male; Middle Aged; Placebos; Receptors, Cell Surface; Tumor Suppressor Proteins	2003
Folic acid reduces nuclear translocation of beta-catenin in rectal mucosal crypts of patients with colorectal adenomas. Cancer letters, 2004, Mar-31, Volume: 206, Issue:1 Topics: Adenoma; Adolescent; Adult; beta Catenin; Cell Nucleus; Colorectal Neoplasms; Cytoskeletal Proteins; Dietary Supplements; ErbB Receptors; Female; Folic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Intestinal Mucosa; Male; Middle Aged; Phosphorylation; Pilot Projects; Placebos; Trans-Activators	2004
Phase I study of CPT-11 and bolus 5-FU/ l-leucovorin in patients with metastatic colorectal cancer. International journal of clinical oncology, 2004, Volume: 9, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Treatment Outcome	2004
Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study. International journal of cancer, 2004, Jul-01, Volume: 110, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antigens, Surface; Colorectal Neoplasms; Double-Blind Method; Folic Acid; Glutamate Carboxypeptidase II; Glycine Hydroxymethyltransferase; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Prospective Studies	2004
Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma. Gut, 2005, Volume: 54, Issue:5 Topics: Adenoma; Aged; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; DNA, Neoplasm; Double-Blind Method; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Leukocytes; Male; Middle Aged; Rectum	2005
A pilot randomised controlled trial to reduce colorectal cancer risk markers associated with B-vitamin deficiency, insulin resistance and colonic inflammation. British journal of cancer, 2005, Sep-19, Volume: 93, Issue:6 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; C-Reactive Protein; Calcium Carbonate; Colitis; Colorectal Neoplasms; Dietary Supplements; Female; Fish Oils; Folic Acid; Humans; Insulin Resistance; Male; Middle Aged; Pilot Projects; Risk Factors; Thiamine; Treatment Outcome; Vitamin B 12 Deficiency; Vitamin B Deficiency	2005
Folate, vitamin B6, multivitamin supplements, and colorectal cancer risk in women. American journal of epidemiology, 2006, Jan-15, Volume: 163, Issue:2 Topics: Colorectal Neoplasms; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; United States; Vitamin B 6; Vitamins	2006
A phase II study of fixed-dose capecitabine and assessment of predictors of toxicity in patients with advanced/metastatic colorectal cancer. British journal of cancer, 2006, Apr-10, Volume: 94, Issue:7 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Diarrhea; Disease Progression; Fatigue; Female; Fluorouracil; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neoplasm Metastasis; Predictive Value of Tests; Survival Analysis	2006
Folate fortification, plasma folate, homocysteine and colorectal adenoma recurrence. International journal of cancer, 2006, Sep-15, Volume: 119, Issue:6 Topics: Adenoma; Aged; Colorectal Neoplasms; Diet; Dietary Fiber; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Neoplasm Recurrence, Local; Risk Factors; Ursodeoxycholic Acid; Vitamin B Complex	2006
Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA, 2007, Jun-06, Volume: 297, Issue:21 Topics: Adenoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chi-Square Distribution; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Neoplasms; Risk; Treatment Failure	2007
Pemetrexed and oxaliplatin for metastatic colorectal cancer: results of a phase I Mayo Cancer Center Research Consortium trial, MC0248. Clinical colorectal cancer, 2007, Volume: 6, Issue:8 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Pemetrexed; Survival Rate; Treatment Outcome; Vitamin B 12	2007
Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas. The Journal of nutrition, 2007, Volume: 137, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Promoter Regions, Genetic; Uracil; Vitamin B 12	2007
Aspirin and folic acid for the prevention of recurrent colorectal adenomas. Gastroenterology, 2008, Volume: 134, Issue:1 Topics: Adenoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemotherapy, Adjuvant; Colonoscopy; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Hematinics; Humans; Male; Middle Aged; Neoplasm Recurrence, Local	2008
DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1994, Volume: 3, Issue:6 Topics: Adenoma; Adult; Aged; Biomarkers, Tumor; Carcinoma; Colorectal Neoplasms; DNA; Female; Folic Acid; Humans; In Vitro Techniques; Intestinal Mucosa; Male; Methylation; Middle Aged; Prospective Studies	1994
Spontaneous or imposed circadian changes in plasma concentrations of 5-fluorouracil coadministered with folinic acid and oxaliplatin: relationship with mucosal toxicity in patients with cancer. Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:2 Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Circadian Rhythm; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Infusion Pumps; Leucovorin; Male; Middle Aged; Mouth Mucosa; Organoplatinum Compounds; Oxaliplatin; Stereoisomerism; Stomatitis; Tetrahydrofolates	1994
5-Fluorouracil combined with the pure [6S]-stereoisomer of folinic acid in high doses for treatment of patients with advanced colorectal carcinoma: a phase I-II study of two consecutive regimens. Advances in experimental medicine and biology, 1993, Volume: 339 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Dose-Response Relationship, Drug; Fluorouracil; Folic Acid; Follow-Up Studies; Humans; Leucovorin; Middle Aged; Pyrimidines; Stereoisomerism	1993
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer research, 1997, Mar-15, Volume: 57, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aspirin; beta Carotene; Case-Control Studies; Cocarcinogenesis; Colorectal Neoplasms; Diet; DNA Methylation; DNA Replication; Double-Blind Method; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Prospective Studies; Risk; Tetrahydrofolates; United States	1997
Changes in folate status as determined by reduction in total plasma homocysteine levels during leucovorin modulation of 5-fluorouracil therapy in cancer patients. Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:9 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colorectal Neoplasms; Creatinine; Erythrocytes; Female; Fluorouracil; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Middle Aged; Vitamin B 12	1998
Linkage disequilibrium between the 677C>T and 1298A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer. Pharmacogenetics, 2002, Volume: 12, Issue:4 Topics: Case-Control Studies; Colorectal Neoplasms; Double-Blind Method; Folic Acid; Gene Frequency; Genotype; Humans; Incidence; Linkage Disequilibrium; Male; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Surveys and Questionnaires	2002

Other Studies

281 other study(ies) available for folic acid and Colorectal Cancer

Article	Year
pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 144 Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Delayed-Action Preparations; Drug Compounding; Drug Liberation; Folic Acid; Hydrogen-Ion Concentration; Irinotecan; Lipids; Liposomes; Mice, Inbred BALB C; Necrosis; Time Factors; Topoisomerase I Inhibitors; Tumor Burden	2021
The Timing and Duration of Folate Restriction Differentially Impacts Colon Carcinogenesis. Nutrients, 2021, Dec-21, Volume: 14, Issue:1 Topics: Animals; Anti-Bacterial Agents; Carcinogenesis; Colorectal Neoplasms; Diet; DNA Repair; Folic Acid; Folic Acid Deficiency; Male; Mice; Mice, Inbred C57BL; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases	2021
The role of folate receptor-positive circulating tumor cell analysis in the diagnosis of colorectal cancer: a retrospective cohort study. International journal of clinical oncology, 2022, Volume: 27, Issue:3 Topics: Biomarkers, Tumor; Colorectal Neoplasms; Folic Acid; Humans; Neoplasm Staging; Neoplastic Cells, Circulating; Retrospective Studies; ROC Curve	2022
Dietary methyl donor nutrients, DNA mismatch repair polymorphisms, and risk of colorectal cancer based on microsatellite instability status. European journal of nutrition, 2022, Volume: 61, Issue:6 Topics: Case-Control Studies; Choline; Colonic Neoplasms; Colorectal Neoplasms; Diet; DNA Mismatch Repair; Folic Acid; Humans; Methionine; Microsatellite Instability; Niacin; Nutrients; Polymorphism, Genetic; Risk Factors	2022
Higher vitamin B6 status is associated with improved survival among patients with stage I-III colorectal cancer. The American journal of clinical nutrition, 2022, 08-04, Volume: 116, Issue:2 Topics: Biomarkers; Carbon; Colorectal Neoplasms; Folic Acid; Humans; Neoplasm Recurrence, Local; Prospective Studies; Pyridoxal Phosphate; Vitamin B 6	2022
Global DNA hypomethylation of colorectal tumours detected in tissue and liquid biopsies may be related to decreased methyl-donor content. BMC cancer, 2022, Jun-02, Volume: 22, Issue:1 Topics: Adenoma; Colorectal Neoplasms; DNA; DNA Methylation; Folate Receptor 2; Folic Acid; Humans; Inflammatory Bowel Diseases; Liquid Biopsy; RNA, Messenger; S-Adenosylmethionine	2022
Mitochondria-targeting folic acid-modified nanoplatform based on mesoporous carbon and a bioactive peptide for improved colorectal cancer treatment. Acta biomaterialia, 2022, 10-15, Volume: 152 Topics: Carbon; Caspase 3; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; Folic Acid; Formaldehyde; Humans; Mitochondria; Nanoparticles; Peptides; Phloroglucinol; Tumor Suppressor Protein p53	2022
Lipid-polymer nanocarrier platform enables X-ray induced photodynamic therapy against human colorectal cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 155 Topics: Antineoplastic Agents; Cell Line, Tumor; Colorectal Neoplasms; Fluorouracil; Folic Acid; Humans; Lipids; Nanoparticles; Photochemotherapy; Photosensitizing Agents; Polymers; Reactive Oxygen Species; Verteporfin; X-Rays	2022
Serum flavin mononucleotide but not riboflavin is inversely associated with the risk of colorectal cancer. Food & function, 2022, Nov-28, Volume: 13, Issue:23 Topics: Case-Control Studies; Colorectal Neoplasms; Flavin Mononucleotide; Folic Acid; Humans; Riboflavin; Vitamin B 6; Vitamins	2022
Interactions between folate intake and genetic predictors of gene expression levels associated with colorectal cancer risk. Scientific reports, 2022, 11-07, Volume: 12, Issue:1 Topics: Case-Control Studies; Colorectal Neoplasms; Folic Acid; Gene Expression; Humans; NF-kappa B; Risk; Risk Factors	2022
The Roles of Nutrients, 2022, Nov-01, Volume: 14, Issue:21 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Colorectal Neoplasms; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide	2022
Activation of progesterone receptor is essential for folic acid-regulated cancer cell proliferation and migration. The Journal of nutritional biochemistry, 2023, Volume: 112 Topics: Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Folic Acid; Humans; Progesterone; Receptors, Progesterone	2023
Cohort profile: Biomarkers related to folate-dependent one-carbon metabolism in colorectal cancer recurrence and survival - the FOCUS Consortium. BMJ open, 2022, 12-22, Volume: 12, Issue:12 Topics: Biomarkers; Carbon; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Prospective Studies; Quality of Life	2022
Folic-Acid-Conjugated Thermoresponsive Polymeric Particles for Targeted Delivery of 5-Fluorouracil to CRC Cells. International journal of molecular sciences, 2023, Jan-10, Volume: 24, Issue:2 Topics: Colorectal Neoplasms; Drug Carriers; Drug Delivery Systems; Fluorouracil; Folic Acid; Humans; Nanoparticles; Polymers; Quality of Life; Spectroscopy, Fourier Transform Infrared	2023
Folic acid-decorated alginate nanoparticles loaded hydrogel for the oral delivery of diferourylmethane in colorectal cancer. International journal of biological macromolecules, 2023, Apr-01, Volume: 233 Topics: Alginates; Animals; Colorectal Neoplasms; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Hydrogels; Nanoparticles	2023
Acetylation of aldehyde dehydrogenase ALDH1L2 regulates cellular redox balance and the chemosensitivity of colorectal cancer to 5-fluorouracil. The Journal of biological chemistry, 2023, Volume: 299, Issue:9 Topics: Acetylation; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Folic Acid; Gene Expression Regulation, Neoplastic; Mice; Mutation; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Sirtuin 3; Up-Regulation	2023
Association between nutrient intake related to the one-carbon metabolism and colorectal cancer risk: a case-control study in the Basque Country. European journal of nutrition, 2023, Volume: 62, Issue:8 Topics: Betaine; Carbon; Case-Control Studies; Choline; Colorectal Neoplasms; Diet; Eating; Folic Acid; Humans; Logistic Models; Risk Factors; Spain	2023
[Top 4 Research Studies of the month for Italian Primary Care Physicians: November 2023.] Recenti progressi in medicina, 2023, Volume: 114, Issue:12 Topics: Adult; Child; Colorectal Neoplasms; Female; Folic Acid; Humans; Neural Tube Defects; Physicians, Primary Care; Pregnancy; Terbinafine	2023
Naturally nutrient rich (NNR) score and the risk of colorectal cancer: a case-control study. BMJ open gastroenterology, 2023, Dec-02, Volume: 10, Issue:1 Topics: Adult; Case-Control Studies; Colorectal Neoplasms; Folic Acid; Humans; Iran; Nutrients	2023
Irinotecan hydrochloride trihydrate loaded folic acid-tailored solid lipid nanoparticles for targeting colorectal cancer: development, characterization, and Journal of microencapsulation, 2019, Volume: 36, Issue:7 Topics: Cell Survival; Colorectal Neoplasms; Drug Carriers; Drug Delivery Systems; Folic Acid; HT29 Cells; Humans; Irinotecan; Nanoparticles; Topoisomerase I Inhibitors	2019
Low folate status, and MTHFR 677C > T and MTR 2756A > G polymorphisms associated with colorectal cancer risk in Thais: a case-control study. Nutrition research (New York, N.Y.), 2019, Volume: 72 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Thailand	2019
To the Editor: Colorectal cancer screening: Folic acid supplementation alters the equation. Cleveland Clinic journal of medicine, 2019, Volume: 86, Issue:12 Topics: Colorectal Neoplasms; Dietary Supplements; Early Detection of Cancer; Folic Acid; Humans	2019
In reply: Colorectal cancer screening. Cleveland Clinic journal of medicine, 2019, Volume: 86, Issue:12 Topics: Colorectal Neoplasms; Dietary Supplements; Early Detection of Cancer; Folic Acid; Humans; Mass Screening	2019
One-carbon metabolites, B vitamins and associations with systemic inflammation and angiogenesis biomarkers among colorectal cancer patients: results from the ColoCare Study. The British journal of nutrition, 2020, 05-28, Volume: 123, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyloid; Biomarkers, Tumor; C-Reactive Protein; Carbon; Colorectal Neoplasms; Cross-Sectional Studies; Female; Folic Acid; Glutamates; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Interleukin-8; Intestines; Linear Models; Male; Middle Aged; Neovascularization, Pathologic; Phosphoric Monoester Hydrolases; Prospective Studies; Statistics, Nonparametric; Tetrahydrofolates; Tumor Necrosis Factor-alpha; Vitamin B Complex; Young Adult	2020
Tumor Targeted Curcumin Delivery by Folate-Modified MPEG-PCL Self-Assembly Micelles for Colorectal Cancer Therapy. International journal of nanomedicine, 2020, Volume: 15 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Cell Line, Tumor; Colorectal Neoplasms; Curcumin; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Female; Folic Acid; Mice, Inbred BALB C; Micelles; Nanostructures; Particle Size; Polyesters; Polyethylene Glycols; Rats	2020
Folic Acid Supplement Intake and Risk of Colorectal Cancer in Women; A Case Control Study. Annals of global health, 2020, 02-27, Volume: 86, Issue:1 Topics: Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Duration of Therapy; Female; Folic Acid; Humans; Information Storage and Retrieval; Iran; Logistic Models; Middle Aged; Neural Tube Defects; Odds Ratio; Protective Factors; Risk Factors; Vitamin B Complex	2020
Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell. Cell death & disease, 2020, 08-06, Volume: 11, Issue:8 Topics: Acetylation; Aminohydrolases; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Colonic Neoplasms; Colorectal Neoplasms; Folic Acid; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Hydrolases; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multifunctional Enzymes; Oxidation-Reduction; Sirtuin 3	2020
Maximizing the potency of oxaliplatin coated nanoparticles with folic acid for modulating tumor progression in colorectal cancer. Materials science & engineering. C, Materials for biological applications, 2021, Volume: 120 Topics: Antineoplastic Agents; Cell Line, Tumor; Colorectal Neoplasms; Drug Carriers; Folic Acid; Humans; Nanoparticles; Oxaliplatin; Polyethylene Glycols	2021
Colorectal cancer incidence in Australia before and after mandatory fortification of bread flour with folic acid. Public health nutrition, 2021, Volume: 24, Issue:8 Topics: Australia; Bread; Colorectal Neoplasms; Flour; Folic Acid; Food, Fortified; Humans; Incidence; Neural Tube Defects	2021
A pH/ultrasonic dual-response step-targeting enterosoluble granule for combined sonodynamic-chemotherapy guided Nanoscale, 2021, Feb-25, Volume: 13, Issue:7 Topics: Animals; Colorectal Neoplasms; Doxorubicin; Folic Acid; Gold; Hydrogen-Ion Concentration; Metal Nanoparticles; Mice; Nanoparticles; Ultrasonics	2021
Association of folate intake and colorectal cancer risk in the postfortification era in US women. The American journal of clinical nutrition, 2021, 07-01, Volume: 114, Issue:1 Topics: Aged; Colorectal Neoplasms; Drug Administration Schedule; Female; Folic Acid; Food, Fortified; Humans; Middle Aged; Risk Factors; United States	2021
A folate-targeted PEGylated cyclodextrin-based nanoformulation achieves co-delivery of docetaxel and siRNA for colorectal cancer. International journal of pharmaceutics, 2021, Sep-05, Volume: 606 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colorectal Neoplasms; Cyclodextrins; Docetaxel; Folic Acid; Mice; Nanoparticles; Polyethylene Glycols; RNA, Small Interfering	2021
Mapping of DNA Hypermethylation and Hypomethylation induced by Folate Deficiency in Sporadic Colorectal Cancer and Clinical Implication Analysis of Hypermethylation Pattern in CBS Promoter. Clinical laboratory, 2017, Apr-01, Volume: 63, Issue:4 Topics: Colorectal Neoplasms; Cystathionine beta-Synthase; DNA; DNA Methylation; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Recurrence, Local; Promoter Regions, Genetic	2017
SL2B aptamer and folic acid dual-targeting DNA nanostructures for synergic biological effect with chemotherapy to combat colorectal cancer. International journal of nanomedicine, 2017, Volume: 12 Topics: Aptamers, Nucleotide; Colorectal Neoplasms; DNA; Doxorubicin; Drug Delivery Systems; Drug Stability; Folic Acid; HT29 Cells; Humans; Intercalating Agents; Molecular Targeted Therapy; Nanostructures	2017
USPSTF recommendations: A 2017 roundup. The Journal of family practice, 2017, Volume: 66, Issue:5 Topics: Advisory Committees; Aspirin; Breast Feeding; Cardiovascular Diseases; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Latent Tuberculosis; Male; Mass Screening; Neural Tube Defects; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pregnancy; Primary Health Care; Primary Prevention; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Assessment; Syphilis; United States; Vitamin B Complex	2017
Low folate metabolic stress reprograms DNA methylation-activated sonic hedgehog signaling to mediate cancer stem cell-like signatures and invasive tumour stage-specific malignancy of human colorectal cancers. International journal of cancer, 2017, 12-15, Volume: 141, Issue:12 Topics: Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Epithelial-Mesenchymal Transition; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Male; Neoplastic Stem Cells; Promoter Regions, Genetic; Signal Transduction; Stress, Physiological; Zinc Finger Protein GLI1	2017
Colorectal cancer-targeted delivery of oxaliplatin via folic acid-grafted solid lipid nanoparticles: preparation, optimization, and in vitro evaluation. Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:6 Topics: Cell Survival; Colorectal Neoplasms; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Folic Acid; HT29 Cells; Humans; Nanoparticles; Organoplatinum Compounds; Oxaliplatin; Particle Size; Surface Properties; Triglycerides	2018
The impact of folate intake on the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohort. British journal of cancer, 2018, Volume: 118, Issue:2 Topics: Aged; Cohort Studies; Colorectal Neoplasms; Diet; Early Detection of Cancer; Female; Folic Acid; Food, Fortified; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Ovarian Neoplasms; Prospective Studies; Prostatic Neoplasms; United States	2018
Dual targeting system by supramolecular complex of folate-conjugated methyl-β-cyclodextrin with adamantane-grafted hyaluronic acid for the treatment of colorectal cancer. International journal of biological macromolecules, 2018, Jul-01, Volume: 113 Topics: Adamantane; Animals; Antineoplastic Agents; Autophagosomes; beta-Cyclodextrins; Biological Transport; Colorectal Neoplasms; Folic Acid; HCT116 Cells; Humans; Hyaluronic Acid; Male; Mice; Mitochondria; Molecular Targeted Therapy; Particle Size; Xenograft Model Antitumor Assays	2018
One-carbon metabolite ratios as functional B-vitamin markers and in relation to colorectal cancer risk. International journal of cancer, 2019, 03-01, Volume: 144, Issue:5 Topics: Betaine; Biomarkers, Tumor; Carbon; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Vitamin B 12; Vitamin B Complex	2019
The association of polymorphisms in folate-metabolizing genes with response to adjuvant chemotherapy of colorectal cancer. Cancer chemotherapy and pharmacology, 2018, Volume: 82, Issue:2 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Folic Acid; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Tetrahydrofolate Dehydrogenase; Young Adult	2018
Simultaneous quantitation of folates, flavins and B Journal of pharmaceutical and biomedical analysis, 2018, Sep-05, Volume: 158 Topics: Adult; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Female; Flavins; Folic Acid; Healthy Volunteers; Humans; Limit of Detection; Male; Middle Aged; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Vitamin B 6	2018
Association of serum folate level with toxicity of capecitabine in patients with colorectal cancers: a prospective cohort study. Hong Kong medical journal = Xianggang yi xue za zhi, 2018, Volume: 24 Suppl 3, Issue:3 Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Female; Folic Acid; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies	2018
Investigation of GHSR and GHRL methylation in colorectal cancer. Epigenomics, 2018, Volume: 10, Issue:12 Topics: Adenoma; Aged; Aged, 80 and over; Biomarkers, Tumor; Colorectal Neoplasms; DNA Methylation; Epigenomics; Female; Folic Acid; Ghrelin; Humans; Male; Middle Aged; MutL Protein Homolog 1; Neoplasm Staging; Polymorphism, Genetic; Receptors, Ghrelin; ROC Curve	2018
Early disease relapse in a patient with colorectal cancer who harbors genetic variants of DPYD, TYMS, MTHFR and DHFR after treatment with 5-fluorouracil-based chemotherapy. Drug metabolism and personalized therapy, 2018, 12-19, Volume: 33, Issue:4 Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Pharmacogenomic Testing; Polymorphism, Genetic; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase	2018
Folate and epigenetics: why we should not forget bacterial biosynthesis. Epigenomics, 2018, Volume: 10, Issue:9 Topics: Adult; Bacteria; Carcinogenesis; Child Development; Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gastrointestinal Microbiome; Humans; Infant, Newborn	2018
Folic acid inhibits colorectal cancer cell migration. The Journal of nutritional biochemistry, 2019, Volume: 63 Topics: Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p27; Extracellular Signal-Regulated MAP Kinases; Folic Acid; Humans; NF-kappa B; rhoA GTP-Binding Protein; Signal Transduction; Up-Regulation	2019
Exploratory metabolomic study to identify blood-based biomarkers as a potential screen for colorectal cancer. Molecular omics, 2019, 02-11, Volume: 15, Issue:1 Topics: Adult; Biomarkers, Tumor; Carbon; Case-Control Studies; Colorectal Neoplasms; Discriminant Analysis; Female; Folic Acid; Humans; Male; Metabolome; Metabolomics; Middle Aged; Principal Component Analysis	2019
Highly sensitive and specific cytosensing of HT 29 colorectal cancer cells using folic acid functionalized-KCC-1 nanoparticles. Biosensors & bioelectronics, 2019, May-01, Volume: 132 Topics: Biosensing Techniques; Colorectal Neoplasms; Flow Cytometry; Folic Acid; HEK293 Cells; HT29 Cells; Humans; Microscopy, Fluorescence; Nanoparticles; Optical Imaging; Porosity; Silicon Dioxide	2019
Dietary B-Vitamin Intake and Risk of Breast, Endometrial, Ovarian and Colorectal Cancer among Canadians. Nutrition and cancer, 2019, Volume: 71, Issue:7 Topics: Breast Neoplasms; Canada; Cohort Studies; Colorectal Neoplasms; Dietary Supplements; Endometrial Neoplasms; Female; Folic Acid; Humans; Male; Micronutrients; Ovarian Neoplasms; Proportional Hazards Models; Risk Factors; Vitamin B Complex	2019
Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer. Nutrients, 2019, Jun-18, Volume: 11, Issue:6 Topics: Adenocarcinoma; Carbon Cycle; Colorectal Neoplasms; Diet; Diet Surveys; DNA Methylation; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Staging; Polymorphism, Single Nucleotide; Vitamin B Complex	2019
Folate pathway genes linked to mitochondrial biogenesis and respiration are associated with outcome of patients with stage III colorectal cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2019, Volume: 41, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Respiration; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Gene Expression Profiling; Humans; Leucovorin; Male; Middle Aged; Organelle Biogenesis; Oxaliplatin; Prognosis; Retrospective Studies; Survival Rate; Young Adult	2019
Prospective study of alcohol consumption and the risk of colorectal cancer before and after folic acid fortification in the United States. Annals of epidemiology, 2013, Volume: 23, Issue:9 Topics: Adult; Aged; Alcohol Drinking; Colorectal Neoplasms; Confidence Intervals; Female; Folic Acid; Follow-Up Studies; Food, Fortified; Humans; Male; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; United States	2013
β,β-carotene 15,15'-monooxygenase and its substrate β-carotene modulate migration and invasion in colorectal carcinoma cells. The American journal of clinical nutrition, 2013, Volume: 98, Issue:2 Topics: beta Carotene; beta-Carotene 15,15'-Monooxygenase; Cell Line, Tumor; Colon; Colorectal Neoplasms; Folic Acid; Gene Expression Regulation, Enzymologic; Humans; Intestinal Mucosa; Intestines; Matrix Metalloproteinase 7; Matrix Metalloproteinases, Secreted; RNA, Messenger; RNA, Small Interfering; Tretinoin; Up-Regulation	2013
Dietary intake of B vitamins and methionine and colorectal cancer risk. Nutrition and cancer, 2013, Volume: 65, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Confidence Intervals; Diet; Female; Folic Acid; Follow-Up Studies; Humans; Male; Methionine; Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2013
Association of dietary and supplemental folate intake and polymorphisms in three FOCM pathway genes with colorectal cancer in a population-based case-control study. Genes, chromosomes & cancer, 2013, Volume: 52, Issue:10 Topics: Aged; Case-Control Studies; Colorectal Neoplasms; Diet; Dietary Supplements; Female; Folic Acid; Genetic Association Studies; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Minor Histocompatibility Antigens; Pennsylvania; Polymorphism, Single Nucleotide	2013
Polymorphisms of folate metabolism-related genes and survival of patients with colorectal cancer in the Korean population. Gene, 2014, Jan-10, Volume: 533, Issue:2 Topics: Aged; Asian People; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Population; Reduced Folate Carrier Protein; Republic of Korea; Survival Analysis; Thymidylate Synthase	2014
High homocysteine is associated with increased risk of colorectal cancer independently of oxidative stress and antioxidant capacities. Clinical nutrition (Edinburgh, Scotland), 2014, Volume: 33, Issue:6 Topics: Adult; Aged; Antioxidants; Blood Pressure; Body Mass Index; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Glutathione Peroxidase; Glutathione Transferase; Healthy Volunteers; Homocysteine; Humans; Linear Models; Male; Middle Aged; Oxidative Stress; Pyridoxal Phosphate; Risk Factors; Serum Albumin; Superoxide Dismutase	2014
[Preoperative chemotherapy in the surgical treatment of colorectal liver metastases]. Magyar sebeszet, 2013, Volume: 66, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Folic Acid; Hepatectomy; Hospitals, General; Humans; Irinotecan; Kaplan-Meier Estimate; Length of Stay; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Operative Time; Organoplatinum Compounds; Oxaliplatin; Surgery Department, Hospital; Treatment Outcome	2013
Associations between cigarette smoking, hormone therapy, and folate intake with incident colorectal cancer by TP53 protein expression level in a population-based cohort of older women. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014, Volume: 23, Issue:2 Topics: Age Factors; Aged; Cohort Studies; Colorectal Neoplasms; Estrogen Replacement Therapy; Female; Folic Acid; Humans; Iowa; Middle Aged; Proportional Hazards Models; Regression Analysis; Risk Factors; Smoking; Tumor Suppressor Protein p53	2014
Pulmonary edema caused by levofolinate treatment in patients with liver metastases from colorectal cancer. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2013, Volume: 80, Issue:6 Topics: Aged; Colorectal Neoplasms; Fatal Outcome; Folic Acid; Humans; Liver Neoplasms; Male; Pulmonary Edema; Radiography, Abdominal; Radiography, Thoracic; Tomography, X-Ray Computed	2013
Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism. Epigenetics, 2014, Volume: 9, Issue:4 Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Colon; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Metabolic Networks and Pathways; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic; Rectum; Vitamin B 12	2014
Folic acid fortification and colorectal cancer risk. American journal of preventive medicine, 2014, Volume: 46, Issue:3 Suppl 1 Topics: Adult; Age Factors; Aged; Black People; Colorectal Neoplasms; Dietary Supplements; Early Detection of Cancer; Female; Folic Acid; Humans; Incidence; Male; Middle Aged; SEER Program; Sex Factors; United States; Vitamin B Complex; White People; Young Adult	2014
Hepatocellular carcinoma and nodular regenerative hyperplasia after chemotherapy for metastatic colorectal carcinoma. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:4 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Colorectal Neoplasms; Drug Therapy; Fluorouracil; Folic Acid; Hepatectomy; Humans; Hyperplasia; Liver; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Vascular Diseases	2014
Uptake of etoposide in CT-26 cells of colorectal cancer using folate targeted dextran stearate polymeric micelles. BioMed research international, 2014, Volume: 2014 Topics: Binding, Competitive; Cell Death; Cell Line, Tumor; Colorectal Neoplasms; Dextrans; Etoposide; Fluorescence; Folic Acid; Humans; Inhibitory Concentration 50; Micelles; Microscopy, Electron, Transmission; Polymers; Proton Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; Stearates	2014
Plasma folate concentrations and colorectal cancer risk: a case-control study nested within the Shanghai Men's Health Study. International journal of cancer, 2014, Nov-01, Volume: 135, Issue:9 Topics: Adult; Aged; Case-Control Studies; China; Colorectal Neoplasms; Folic Acid; Follow-Up Studies; Humans; Male; Men's Health; Middle Aged; Neoplasm Staging; Prognosis; Prospective Studies; Risk Factors	2014
Low folate levels are associated with reduced risk of colorectal cancer in a population with low folate status. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014, Volume: 23, Issue:10 Topics: Adult; Case-Control Studies; Chromatography, Liquid; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Odds Ratio; Risk Factors; Tandem Mass Spectrometry	2014
Dietary polyamine intake and polyamines measured in urine. Nutrition and cancer, 2014, Volume: 66, Issue:7 Topics: Aged; Aged, 80 and over; Anthropometry; Colorectal Neoplasms; Cross-Sectional Studies; Diet; Energy Intake; Folic Acid; Humans; Male; Middle Aged; Nutrition Assessment; Pilot Projects; Polyamines; Reproducibility of Results; Spermidine; Surveys and Questionnaires	2014
Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region. The American journal of clinical nutrition, 2014, Volume: 100, Issue:6 Topics: Adult; Aged; Alcohol Drinking; Colorectal Neoplasms; DNA Methylation; Energy Intake; Epigenesis, Genetic; Ethanol; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Insulin-Like Growth Factor II; Male; Methionine; Middle Aged; Proportional Hazards Models; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6	2014
High serum folate might have a potential dual effect on risk of colorectal cancer. Clinical nutrition (Edinburgh, Scotland), 2015, Volume: 34, Issue:5 Topics: Adult; Aged; Body Mass Index; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pyridoxal Phosphate; Risk Factors	2015
Diet and physical activity in the prevention of colorectal cancer. Journal of the National Comprehensive Cancer Network : JNCCN, 2014, Volume: 12, Issue:12 Topics: Calcium; Colorectal Neoplasms; Diet; Dietary Fats; Dietary Fiber; Dietary Supplements; Folic Acid; Humans; Meat; Motor Activity; Risk Factors; Vitamin D	2014
Red blood cell folate and plasma folate are not associated with risk of incident colorectal cancer in the Women's Health Initiative observational study. International journal of cancer, 2015, Aug-15, Volume: 137, Issue:4 Topics: Aged; Case-Control Studies; Colorectal Neoplasms; Erythrocytes; Female; Folic Acid; Humans; Middle Aged; Plasma; Postmenopause; Risk Factors	2015
DNA methylation and expression of the folate transporter genes in colorectal cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:7 Topics: Colorectal Neoplasms; CpG Islands; DNA Methylation; Epigenesis, Genetic; Folate Receptor 1; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Staging; Promoter Regions, Genetic; Proton-Coupled Folate Transporter; Replication Protein C	2015
Application of artificial neural networks to link genetic and environmental factors to DNA methylation in colorectal cancer. Epigenomics, 2015, Volume: 7, Issue:2 Topics: Aged; Colorectal Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Gene-Environment Interaction; Humans; Life Style; Male; Middle Aged; Neural Networks, Computer; Polymorphism, Genetic; Promoter Regions, Genetic	2015
Genetic Variation in Glutamate Carboxypeptidase II and Interaction with Dietary Natural Vitamin C May Predict Risk for Adenomatous Polyp Occurrence. Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:10 Topics: Adenomatous Polyps; Adult; Aged; Aged, 80 and over; Ascorbic Acid; Case-Control Studies; Colorectal Neoplasms; Diet; Folic Acid; Genotype; Glutamate Carboxypeptidase II; Homocysteine; Humans; Middle Aged; Polymorphism, Single Nucleotide; Pteroylpolyglutamic Acids; Risk Factors; Tetrahydrofolates; Vitamins	2015
Folate and nutrients involved in the 1-carbon cycle in the pretreatment of patients for colorectal cancer. Nutrients, 2015, Jun-02, Volume: 7, Issue:6 Topics: Aged; Brazil; Carbon Cycle; Choline; Colorectal Neoplasms; Dietary Carbohydrates; Dietary Proteins; Dietary Supplements; Energy Intake; Female; Folic Acid; Humans; Male; Middle Aged; Riboflavin; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6	2015
Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans. Scientific reports, 2015, Jun-05, Volume: 5 Topics: 3' Untranslated Regions; Adenocarcinoma; Aged; Colorectal Neoplasms; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Republic of Korea	2015
Folate-mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study. Cancer, 2015, Oct-15, Volume: 121, Issue:20 Topics: Aged; Biomarkers; Case-Control Studies; Colorectal Neoplasms; DNA-Binding Proteins; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Histone-Lysine N-Methyltransferase; Humans; Logistic Models; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Minor Histocompatibility Antigens; Nuclear Proteins; Polymorphism, Single Nucleotide; Postmenopause; Risk Assessment; Transcription Factors; Vitamin B Complex	2015
3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population. PloS one, 2015, Volume: 10, Issue:7 Topics: 3' Untranslated Regions; Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; DEAD-box RNA Helicases; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Karyopherins; Male; MicroRNAs; Middle Aged; Polymorphism, Single Nucleotide; ran GTP-Binding Protein; Republic of Korea; Ribonuclease III; Risk; RNA, Neoplasm; Tumor Burden	2015
Expression of Folate Pathway Genes in Stage III Colorectal Cancer Correlates with Recurrence Status Following Adjuvant Bolus 5-FU-Based Chemotherapy. Molecular medicine (Cambridge, Mass.), 2015, Jul-17, Volume: 21 Topics: Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Leucovorin; Male; Middle Aged; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Proton-Coupled Folate Transporter; Reduced Folate Carrier Protein; Signal Transduction	2015
Unmetabolized Folic Acid in Prediagnostic Plasma and the Risk of Colorectal Cancer. Journal of the National Cancer Institute, 2015, Volume: 107, Issue:12 Topics: Adult; Case-Control Studies; Colorectal Neoplasms; Cytosine; Dietary Supplements; Female; Folic Acid; Food, Fortified; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Assessment; Risk Factors; Sex Factors; Thymine	2015
Postdiagnostic intake of one-carbon nutrients and alcohol in relation to colorectal cancer survival. The American journal of clinical nutrition, 2015, Volume: 102, Issue:5 Topics: Adult; Alcohol Drinking; Cohort Studies; Colon; Colorectal Neoplasms; Databases, Factual; Diet; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Food, Fortified; Humans; Male; Neoplasm Staging; Prognosis; Prospective Studies; Rectum; Surveys and Questionnaires; Survival Analysis; United States	2015
In Vivo Antitumor Activity of Folate-Conjugated Cholic Acid-Polyethylenimine Micelles for the Codelivery of Doxorubicin and siRNA to Colorectal Adenocarcinomas. Molecular pharmaceutics, 2015, Dec-07, Volume: 12, Issue:12 Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Cholic Acid; Colorectal Neoplasms; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Folic Acid; Humans; Mice; Mice, Nude; Micelles; Nanoconjugates; Particle Size; Polyethylene Glycols; Polyethyleneimine; RNA, Small Interfering; Vascular Endothelial Growth Factor A	2015
Simultaneous Analysis of SEPT9 Promoter Methylation Status, Micronuclei Frequency, and Folate-Related Gene Polymorphisms: The Potential for a Novel Blood-Based Colorectal Cancer Biomarker. International journal of molecular sciences, 2015, Dec-01, Volume: 16, Issue:12 Topics: Adenomatous Polyposis Coli; Aged; Aged, 80 and over; Alleles; Biomarkers, Tumor; Case-Control Studies; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Gene Frequency; Genotype; Humans; INDEL Mutation; Male; Micronuclei, Chromosome-Defective; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; ROC Curve; Septins	2015
Ocoxin® oral solution slows down tumor growth in an experimental model of colorectal cancer metastasis to the liver in Balb/c mice. Oncology reports, 2016, Volume: 35, Issue:3 Topics: Animals; Apoptosis; Ascorbic Acid; Caspase 3; Cell Proliferation; Colorectal Neoplasms; Folic Acid; Gene Expression Regulation, Neoplastic; Glycyrrhizic Acid; Humans; Ki-67 Antigen; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Pantothenic Acid; Plant Extracts; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Zinc; Zinc Sulfate	2016
Gene-Nutrient Interaction between Folate and Dihydrofolate Reductase in Risk for Adenomatous Polyp Occurrence: A Preliminary Report. Journal of nutritional science and vitaminology, 2015, Volume: 61, Issue:6 Topics: Adenomatous Polyps; Aged; Alleles; Colorectal Neoplasms; Diet; Epigenesis, Genetic; Female; Folic Acid; Genotype; Humans; Male; Middle Aged; Nutritional Status; Polymorphism, Genetic; Risk Factors; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates	2015
Subpopulation Treatment Effect Pattern Plot (STEPP) analysis for continuous, binary, and count outcomes. Clinical trials (London, England), 2016, Volume: 13, Issue:4 Topics: Adenoma; Aspirin; Biomarkers, Tumor; Colorectal Neoplasms; Data Interpretation, Statistical; Folic Acid; Humans; Models, Statistical; Randomized Controlled Trials as Topic; Risk; Survival Analysis; Treatment Outcome	2016
Cullin 3 targets methionine adenosyltransferase IIα for ubiquitylation-mediated degradation and regulates colorectal cancer cell proliferation. The FEBS journal, 2016, Volume: 283, Issue:13 Topics: Blotting, Western; Cell Proliferation; Colorectal Neoplasms; Cullin Proteins; Folic Acid; HCT116 Cells; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Immunoprecipitation; In Vitro Techniques; Methionine Adenosyltransferase; Proteolysis; RNA Interference; Ubiquitination	2016
Progesterone receptor activation is required for folic acid-induced anti-proliferation in colorectal cancer cell lines. Cancer letters, 2016, 08-10, Volume: 378, Issue:2 Topics: Antineoplastic Agents; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Folate Receptors, GPI-Anchored; Folic Acid; HCT116 Cells; HT29 Cells; Humans; Oligonucleotides, Antisense; Receptors, Progesterone; RNA Interference; Signal Transduction; Transfection; Tumor Suppressor Protein p53	2016
People with low serum folate levels have higher risk of colorectal adenoma/advanced colorectal adenoma occurrence and recurrence in China. The Journal of international medical research, 2016, Volume: 44, Issue:4 Topics: Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; China; Colorectal Neoplasms; Female; Folic Acid; Humans; Logistic Models; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Risk Factors; Young Adult	2016
Components of One-carbon Metabolism Other than Folate and Colorectal Cancer Risk. Epidemiology (Cambridge, Mass.), 2016, Volume: 27, Issue:6 Topics: Aged; Amino Acids; Betaine; Biomarkers; Biomarkers, Tumor; Case-Control Studies; Choline; Colorectal Neoplasms; Female; Folic Acid; Follow-Up Studies; Humans; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Prospective Studies; Protective Factors; Sarcosine; Sweden	2016
Pretreatment Serum Folate Levels and Toxicity/Efficacy in Colorectal Cancer Patients Treated With 5-Fluorouracil and Folinic Acid. Clinical colorectal cancer, 2016, Volume: 15, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Leucovorin; Male; Middle Aged; Prospective Studies	2016
The importance of mitochondrial folate enzymes in human colorectal cancer. Oncology reports, 2017, Volume: 37, Issue:1 Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinogenesis; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mitochondria; Prognosis; Survival Analysis	2017
pH-responsive Virus-like Nanoparticles with Enhanced Tumour-targeting Ligands for Cancer Drug Delivery. Scientific reports, 2016, 11-24, Volume: 6 Topics: Acrylic Resins; Antibiotics, Antineoplastic; Caco-2 Cells; Colorectal Neoplasms; Doxorubicin; Drug Delivery Systems; Drug Liberation; Electrophoresis, Agar Gel; Folic Acid; Hepatitis B Core Antigens; HT29 Cells; Humans; Hydrogen-Ion Concentration; Nanoparticles	2016
Untangling the role of one-carbon metabolism in colorectal cancer risk: a comprehensive Bayesian network analysis. Scientific reports, 2017, 02-24, Volume: 7 Topics: Adult; Aged; Bayes Theorem; Biomarkers, Tumor; Carbon; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Machine Learning; Male; Metabolome; Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Riboflavin; Risk Factors; Vitamin B 6	2017
Does folic acid supplementation prevent or promote colorectal cancer? Results from model-based predictions. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:6 Topics: Colorectal Neoplasms; DNA Methylation; DNA Replication; Folic Acid; Humans; Models, Statistical; Mutation; Risk	2008
Prediagnostic plasma folate and the risk of death in patients with colorectal cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jul-01, Volume: 26, Issue:19 Topics: Adult; Aged; Chi-Square Distribution; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Factors; Surveys and Questionnaires; United States	2008
Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status. World journal of gastroenterology, 2008, Jun-21, Volume: 14, Issue:23 Topics: Adaptor Proteins, Signal Transducing; Case-Control Studies; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Folic Acid; Gene Expression Regulation, Neoplastic; Genotype; Humans; Iran; Methylenetetrahydrofolate Reductase (NADPH2); MutL Protein Homolog 1; MutS Homolog 2 Protein; Nuclear Proteins; Odds Ratio; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Assessment; Vitamin B 12	2008
Methylene tetrahydrofolate reductase genotype modifies the chemopreventive effect of folate in colorectal adenoma, but not colorectal cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:9 Topics: Adenoma; Aged; Aged, 80 and over; Alcohol Drinking; Case-Control Studies; Chi-Square Distribution; Colorectal Neoplasms; England; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors; Scotland; Surveys and Questionnaires	2008
Risk of colorectal cancer associated with the C677T polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients. The American journal of clinical nutrition, 2008, Volume: 88, Issue:5 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Folic Acid; Genotype; Glycine Hydroxymethyltransferase; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors	2008
Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. The Journal of nutrition, 2008, Volume: 138, Issue:12 Topics: Aged; Cohort Studies; Colorectal Neoplasms; Diet; Diet Surveys; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Netherlands; Prospective Studies; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B 6	2008
Folic acid and sodium butyrate prevent tumorigenesis in a mouse model of colorectal cancer. Epigenetics, 2008, Volume: 3, Issue:6 Topics: Acetylation; Animals; Body Weight; Butyrates; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Diet; Dietary Supplements; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Histones; Mice; Mice, Inbred ICR; Odds Ratio; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Transcription, Genetic	2008
Vitamin supplements and cancer prevention: where do randomized controlled trials stand? Journal of the National Cancer Institute, 2009, Jan-07, Volume: 101, Issue:1 Topics: Antioxidants; Ascorbic Acid; beta Carotene; Colorectal Neoplasms; Confounding Factors, Epidemiologic; Dietary Supplements; Female; Folic Acid; Humans; Incidence; Lung Neoplasms; Male; Neoplasms; Primary Prevention; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Assessment; Selenium; United States; Vitamin B 12; Vitamin B 6; Vitamin E	2009
Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenoma; Adult; Aged; Alcohol Drinking; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genotype; Humans; Logistic Models; Male; Middle Aged; Polymorphism, Genetic; Risk; Surveys and Questionnaires	2009
The reduced folate carrier (RFC1) 80G > A and folate hydrolase 1 (FOLH1) 1561C > T polymorphisms and the risk of colorectal cancer: a nested case-referent study. Scandinavian journal of clinical and laboratory investigation, 2008, Volume: 68, Issue:5 Topics: Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genotype; Homocysteine; Humans; Male; Membrane Transport Proteins; Middle Aged; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk Factors	2008
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice. Gut, 2009, Volume: 58, Issue:6 Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Colorectal Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Pregnancy; Prenatal Nutritional Physiological Phenomena; Random Allocation; Thymine Nucleotides; Uridine Triphosphate; Weaning	2009
Dietary B vitamin and methionine intakes and plasma folate are not associated with colorectal cancer risk in Chinese women. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:3 Topics: Adult; Aged; Case-Control Studies; China; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Logistic Models; Methionine; Middle Aged; Niacinamide; Proportional Hazards Models; Prospective Studies; Registries; Riboflavin; Risk; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6	2009
The relationship between gene-specific DNA methylation in leukocytes and normal colorectal mucosa in subjects with and without colorectal tumors. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:3 Topics: Adenoma; Aged; Analysis of Variance; Biomarkers; Case-Control Studies; Chi-Square Distribution; Colonic Polyps; Colorectal Neoplasms; CpG Islands; DNA Methylation; Estrogen Receptor alpha; Female; Folic Acid; Humans; Intestinal Mucosa; Leukocytes; Male; Middle Aged; Polymerase Chain Reaction; Statistics, Nonparametric	2009
Prospective study of plasma vitamin B6 and risk of colorectal cancer in men. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:4 Topics: Adenoma; Adult; Aged; Aged, 80 and over; C-Reactive Protein; Case-Control Studies; Colorectal Neoplasms; Folic Acid; Humans; Incidence; Interleukin-6; Male; Middle Aged; Physicians; Prospective Studies; Pyridoxal Phosphate; Randomized Controlled Trials as Topic; Tumor Necrosis Factor-alpha; Vitamin B 12; Vitamin B 6	2009
Effect of folic acid supplementation on the progression of colorectal aberrant crypt foci. Carcinogenesis, 2009, Volume: 30, Issue:9 Topics: Animals; Cell Proliferation; Colorectal Neoplasms; Dietary Supplements; Disease Progression; Folic Acid; Homocysteine; Liver; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley	2009
Plasma levels of B vitamins and colorectal cancer risk: the multiethnic cohort study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:8 Topics: Aged; Alcohol Drinking; C-Reactive Protein; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Vitamin B 6; Vitamin B Complex	2009
Mesalamine protects against colorectal cancer in inflammatory bowel disease. Digestive diseases and sciences, 2010, Volume: 55, Issue:6 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Case-Control Studies; Chi-Square Distribution; Colorectal Neoplasms; Disease Progression; Female; Folic Acid; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Logistic Models; Male; Mesalamine; Middle Aged; Odds Ratio; Retrospective Studies; Risk Assessment; Risk Factors; ROC Curve; Treatment Outcome; Young Adult	2010
Folate-mediated targeting of albumin conjugates of paclitaxel obtained through a heterogeneous phase system. International journal of pharmaceutics, 2009, Dec-01, Volume: 382, Issue:1-2 Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Carrier Proteins; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Chromatography, Gel; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Folate Receptors, GPI-Anchored; Folic Acid; HT29 Cells; Humans; Inhibitory Concentration 50; KB Cells; Nasopharyngeal Neoplasms; Paclitaxel; Polyethylene Glycols; Receptors, Cell Surface; Serum Albumin; Solubility; Technology, Pharmaceutical; Triazines	2009
Serum vitamin B12 and folate status among patients with chemotherapy treatment for advanced colorectal cancer. Upsala journal of medical sciences, 2009, Volume: 114, Issue:3 Topics: Aged; Antineoplastic Agents; Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Vitamin B 12	2009
Antagonistic effects of aspirin and folic acid on inflammation markers and subsequent risk of recurrent colorectal adenomas. Journal of the National Cancer Institute, 2009, Dec-02, Volume: 101, Issue:23 Topics: Adenoma; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; C-Reactive Protein; Colorectal Neoplasms; Drug Administration Schedule; Drug Antagonism; Female; Folic Acid; Humans; Inflammation; Interleukin-6; Male; Middle Aged; Risk Assessment; Risk Factors; Tumor Necrosis Factor-alpha	2009
Dietary folate, alcohol and B vitamins in relation to LINE-1 hypomethylation in colon cancer. Gut, 2010, Volume: 59, Issue:6 Topics: Alcohol Drinking; Colorectal Neoplasms; Diet; DNA Methylation; DNA, Neoplasm; Ethanol; Female; Folic Acid; Humans; Long Interspersed Nucleotide Elements; Male; Prospective Studies; Vitamin B 12; Vitamin B 6	2010
Determinants of homocysteine levels in colorectal and breast cancer patients. Anticancer research, 2009, Volume: 29, Issue:10 Topics: Adult; Breast Neoplasms; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Inflammation Mediators; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutritional Status; Polymorphism, Single Nucleotide	2009
Uracil misincorporation into DNA and folic acid supplementation. The American journal of clinical nutrition, 2010, Volume: 91, Issue:1 Topics: Adenoma; Aged; Alcohol Drinking; Aspirin; Colonoscopy; Colorectal Neoplasms; Dietary Supplements; DNA; Female; Folic Acid; Humans; Intestinal Mucosa; Male; Middle Aged; Neoplasm Recurrence, Local; Placebos; Randomized Controlled Trials as Topic; Risk Factors; Uracil	2010
One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent study. Cancer causes & control : CCC, 2010, Volume: 21, Issue:4 Topics: Aged; Carbon; Case-Control Studies; Colorectal Neoplasms; CpG Islands; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Sweden; Vitamin B 12	2010
Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer causes & control : CCC, 2010, Volume: 21, Issue:4 Topics: Adult; Aged; Carrier Proteins; Case-Control Studies; Colorectal Neoplasms; Family Health; Female; Folate Receptor 1; Folate Receptors, GPI-Anchored; Folic Acid; gamma-Glutamyl Hydrolase; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Logistic Models; Male; Membrane Transport Proteins; Middle Aged; Peptide Synthases; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Reduced Folate Carrier Protein; Registries; Risk Factors; Surveys and Questionnaires	2010
Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:1 Topics: Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Diet; Dietary Supplements; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Microsatellite Instability; Middle Aged; Polymorphism, Single Nucleotide; Registries; Risk Factors	2010
Association between MTHFR polymorphism (C677T) with nonfamilial colorectal cancer. Oncology research, 2009, Volume: 18, Issue:2-3 Topics: Aged; Base Sequence; Colorectal Neoplasms; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Molecular Sequence Data; Polymorphism, Genetic	2009
Folic acid-conjugated chitosan nanoparticles enhanced protoporphyrin IX accumulation in colorectal cancer cells. Bioconjugate chemistry, 2010, Apr-21, Volume: 21, Issue:4 Topics: Aminolevulinic Acid; Caco-2 Cells; Carrier Proteins; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Nanoparticles; Protoporphyrins; Receptors, Cell Surface	2010
Plasma folate, related genetic variants, and colorectal cancer risk in EPIC. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Prospective Studies; Risk Factors; Survival Rate	2010
A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:7 Topics: Case-Control Studies; Colorectal Neoplasms; Dietary Supplements; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Male; Microsatellite Instability; Middle Aged; Polymorphism, Single Nucleotide; United States; Vitamin B 12	2010
Use of folic acid-containing supplements after a diagnosis of colorectal cancer in the Colon Cancer Family Registry. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:8 Topics: Antineoplastic Agents; Colorectal Neoplasms; Dietary Supplements; Family Health; Female; Folic Acid; Follow-Up Studies; Health Behavior; Humans; Male; Middle Aged; Patient Acceptance of Health Care; Prognosis; Registries; Sex Factors; Surveys and Questionnaires	2010
Plasma vitamins B2, B6, and B12, and related genetic variants as predictors of colorectal cancer risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:10 Topics: Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Riboflavin; Risk Factors; Vitamin B 12; Vitamin B 6	2010
Revisiting the goldilocks phenomenon: folate and colorectal cancer risk. The American journal of gastroenterology, 2010, Volume: 105, Issue:9 Topics: Carcinoma; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Risk	2010
The conundrum of folate and colorectal cancer (CRC) risk. European journal of clinical nutrition, 2010, Volume: 64, Issue:12 Topics: Colorectal Neoplasms; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Risk Factors	2010
Folate and one-carbon metabolism and its impact on aberrant DNA methylation in cancer. Advances in genetics, 2010, Volume: 71 Topics: Animals; Carbon; Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Humans; Pregnancy	2010
Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer. Cancer causes & control : CCC, 2011, Volume: 22, Issue:1 Topics: Aged; Colorectal Neoplasms; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Methyltransferases; Middle Aged; Polymerase Chain Reaction; Promoter Regions, Genetic; Vitamin B 6	2011
Effects of folic acid plus vitamin B12 vs placebo in myocardial infarction survivors. JAMA, 2010, Oct-27, Volume: 304, Issue:16 Topics: Colorectal Neoplasms; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Myocardial Infarction; Neoplasms; North America; Risk; Vitamin B 12; Vitamin B Complex	2010
Polymorphisms in genes involved in folate metabolism and plasma DNA methylation in colorectal cancer patients. Oncology reports, 2011, Volume: 25, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adaptor Proteins, Signal Transducing; Biomarkers, Tumor; Colorectal Neoplasms; DNA; DNA Methylation; DNA-Binding Proteins; Female; Folic Acid; Genes, p16; Genetic Predisposition to Disease; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; MutL Protein Homolog 1; Neoplasm Staging; Nuclear Proteins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Tumor Protein p73; Tumor Suppressor Proteins	2011
Viewing the epigenetics of colorectal cancer through the window of folic acid effects. Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:12 Topics: Animals; Anticarcinogenic Agents; Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Folic Acid; Humans	2010
Alginate-folic acid-modified chitosan nanoparticles for photodynamic detection of intestinal neoplasms. Biomaterials, 2011, Volume: 32, Issue:8 Topics: Alginates; Animals; Biocompatible Materials; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Drug Carriers; Fluoresceins; Folic Acid; Glucuronic Acid; Hexuronic Acids; Humans; Intestinal Neoplasms; Materials Testing; Mice; Mice, Inbred C57BL; Models, Molecular; Nanoparticles; Photochemistry	2011
Folic acid and prevention of colorectal adenomas: a combined analysis of randomized clinical trials. International journal of cancer, 2011, Jul-01, Volume: 129, Issue:1 Topics: Adenoma; Aged; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic	2011
Quantitative analysis of tissue folate using ultra high-performance liquid chromatography tandem mass spectrometry. Analytical biochemistry, 2011, Apr-15, Volume: 411, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Folic Acid; Humans; Intestinal Mucosa; Liver; Mice; Rats; Tandem Mass Spectrometry	2011
Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair. The Journal of nutritional biochemistry, 2011, Volume: 22, Issue:11 Topics: Aminohydrolases; Animals; Colorectal Neoplasms; Diet; DNA Methylation; DNA Polymerase beta; DNA Repair; Folic Acid; Folic Acid Deficiency; Formate-Tetrahydrofolate Ligase; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Multienzyme Complexes; RNA, Messenger; Serine; Tetrahydrofolates; Uracil-DNA Glycosidase	2011
Folate intake and risk of colorectal cancer and adenoma: modification by time. The American journal of clinical nutrition, 2011, Volume: 93, Issue:4 Topics: Adenoma; Adult; Aged; Colorectal Neoplasms; Diet Surveys; Female; Folic Acid; Humans; Male; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; Time; Vitamin B Complex	2011
Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study. Cancer causes & control : CCC, 2011, Volume: 22, Issue:4 Topics: Adenoma; Aged; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Biological; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk Factors; Sigmoidoscopy	2011
In vivo evidence for a significant role of folylpolyglutamate synthase in combined chemotherapy with oral fluoropyrimidine, UFT or S-1, and leucovorin. Oncology reports, 2011, Volume: 25, Issue:5 Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Fluorouracil; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Leucovorin; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Peptide Synthases; RNA, Small Interfering; Xenograft Model Antitumor Assays	2011
New Zealand should have mandatory fortification of bread with folic acid: no. Journal of primary health care, 2010, Volume: 2, Issue:1 Topics: Bread; Colorectal Neoplasms; Folic Acid; Food, Fortified; Humans; Male; Neural Tube Defects; New Zealand; Nutrition Policy; Prostatic Neoplasms; Risk	2010
Effect of maternal and postweaning folic acid supplementation on colorectal cancer risk in the offspring. Gut, 2011, Volume: 60, Issue:12 Topics: Animals; Animals, Newborn; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; Female; Folic Acid; Intestinal Mucosa; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Risk Factors; Weaning	2011
High levels of folate from supplements and fortification are not associated with increased risk of colorectal cancer. Gastroenterology, 2011, Volume: 141, Issue:1 Topics: Aged; Colorectal Neoplasms; Diet; Dietary Supplements; Feeding Behavior; Female; Folic Acid; Food, Fortified; Humans; Incidence; Male; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Surveys and Questionnaires; Time Factors; United States	2011
Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2011, Volume: 32, Issue:5 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenocarcinoma; Brazil; Colorectal Neoplasms; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Heterozygote; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases; Pilot Projects; Polymorphism, Single Nucleotide; Risk; Thymidylate Synthase	2011
Determination of the minimal essential serum folate concentration for reduced risk of colorectal adenoma. Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:5 Topics: Adenoma; Adult; Aged; Colorectal Neoplasms; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Hospitals, Teaching; Humans; Japan; Male; Mass Screening; Middle Aged; Prevalence; Prospective Studies; Risk; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency	2011
Fruit, vegetables, and folate: cultivating the evidence for cancer prevention. Gastroenterology, 2011, Volume: 141, Issue:1 Topics: Colorectal Neoplasms; Diet; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Food, Fortified; Fruit; Humans; Risk Assessment; Risk Factors; Vegetables	2011
Maternal B vitamin supplementation from preconception through weaning suppresses intestinal tumorigenesis in Apc1638N mouse offspring. Gut, 2011, Volume: 60, Issue:12 Topics: Animals; Animals, Newborn; Colorectal Neoplasms; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Pregnancy; Prenatal Exposure Delayed Effects; Riboflavin; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D Deficiency; Wnt Signaling Pathway	2011
Pre- and postfortification intake of folate and risk of colorectal cancer in a large prospective cohort study in the United States. The American journal of clinical nutrition, 2011, Volume: 94, Issue:4 Topics: Aged; Cohort Studies; Colorectal Neoplasms; Diet; Dietary Supplements; Edible Grain; Folic Acid; Follow-Up Studies; Food, Fortified; Humans; Incidence; Legislation, Food; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Registries; Risk; Surveys and Questionnaires; United States	2011
Folic acid and colorectal cancer: unwarranted fears. Canadian family physician Medecin de famille canadien, 2011, Volume: 57, Issue:8 Topics: Colorectal Neoplasms; Evidence-Based Medicine; Female; Folic Acid; Humans; Neural Tube Defects; Observation; Pregnancy; Randomized Controlled Trials as Topic	2011
Folate consumption and cancer risk: a confirmation and some reassurance, but we're not out of the woods quite yet. The American journal of clinical nutrition, 2011, Volume: 94, Issue:4 Topics: Colorectal Neoplasms; Folic Acid; Food, Fortified; Humans; Male	2011
Folate may help lower risk of colorectal cancer. Cancer, 2011, Dec-01, Volume: 117, Issue:23 Topics: Colorectal Neoplasms; Folic Acid; Humans; Risk	2011
Methylenetetrahydrofolate reductase genotypes and haplotypes associated with susceptibility to colorectal cancer in an eastern Chinese Han population. Genetics and molecular research : GMR, 2011, Dec-14, Volume: 10, Issue:4 Topics: Aged; Asian People; China; Colorectal Neoplasms; Ethnicity; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Genetics, Population; Haplotypes; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length	2011
Folic acid supplementary reduce the incidence of adenocarcinoma in a mouse model of colorectal cancer: microarray gene expression profile. Journal of experimental & clinical cancer research : CR, 2011, Volume: 30 Topics: Adenocarcinoma; Animals; Colorectal Neoplasms; Disease Models, Animal; Female; Folic Acid; Mice; Mice, Inbred ICR; Random Allocation; Risk Factors; Transcriptome	2011
Dietary intake of folate and alcohol, MTHFR C677T polymorphism, and colorectal cancer risk in Korea. The American journal of clinical nutrition, 2012, Volume: 95, Issue:2 Topics: Aged; Alcohol Drinking; Case-Control Studies; Colorectal Neoplasms; Diet; Ethanol; Female; Folic Acid; Homozygote; Humans; Korea; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors; Vitamin B Complex	2012
Plasma folate, methylenetetrahydrofolate reductase (MTHFR), and colorectal cancer risk in three large nested case-control studies. Cancer causes & control : CCC, 2012, Volume: 23, Issue:4 Topics: Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors	2012
Influence of a fat-rich diet, folic acid supplementation and a human-relevant concentration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on the induction of preneoplastic lesions in the rat colon. Archives of toxicology, 2012, Volume: 86, Issue:5 Topics: Aberrant Crypt Foci; Animals; Colon; Colorectal Neoplasms; Diet, High-Fat; Dietary Supplements; Folic Acid; Humans; Imidazoles; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Risk Factors	2012
Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa. Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:7 Topics: Aged; Alu Elements; Case-Control Studies; Chromatography, Liquid; Colon; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Humans; Long Interspersed Nucleotide Elements; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Prospective Studies; Rectum; Tandem Mass Spectrometry	2012
A candidate gene study of one-carbon metabolism pathway genes and colorectal cancer risk. The British journal of nutrition, 2013, Mar-28, Volume: 109, Issue:6 Topics: Aged; Carbon; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Mutagenesis, Insertional; Nucleotides; One-Carbon Group Transferases; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Transcobalamins; Vitamin B 12	2013
Effects of unconjugated bilirubin on chromosomal damage in individuals with Gilbert's syndrome measured with the micronucleus cytome assay. Mutagenesis, 2012, Volume: 27, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Bilirubin; Chromosome Aberrations; Colorectal Neoplasms; Comet Assay; Cytokinesis; DNA Damage; Endpoint Determination; Female; Folic Acid; Gilbert Disease; Homocysteine; Humans; Lung Neoplasms; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Vitamin B 12; Young Adult	2012
Validation of a quantitative FFQ for a study of diet and risk of colorectal adenoma among Japanese Brazilians. Public health nutrition, 2013, Volume: 16, Issue:8 Topics: Adult; Aged; Ascorbic Acid; Asian People; Brazil; Case-Control Studies; Colorectal Neoplasms; Cross-Sectional Studies; Diet Records; Dietary Fats; Dietary Fiber; Feeding Behavior; Female; Folic Acid; Humans; Linear Models; Male; Middle Aged; Nutrition Assessment; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin A	2013
Association of folate intake, dietary habits, smoking and COX-2 promotor -765G>C polymorphism with K-ras mutation in patients with colorectal cancer. Journal of the Egyptian National Cancer Institute, 2012, Volume: 24, Issue:3 Topics: Adult; Aged; Colorectal Neoplasms; Cyclooxygenase 2; Diet; DNA Mutational Analysis; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Genetic Association Studies; Humans; Logistic Models; Male; Middle Aged; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Retrospective Studies; Smoking; Young Adult	2012
Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice. Molecular nutrition & food research, 2013, Volume: 57, Issue:4 Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; beta-Carotene 15,15'-Monooxygenase; Bone Morphogenetic Protein 5; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cornified Envelope Proline-Rich Proteins; Diet; DNA Damage; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gene Expression; Genotype; Intestinal Mucosa; Intestinal Neoplasms; Intestines; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; PPAR alpha; Retinal Dehydrogenase; Retinoids; Up-Regulation	2013
Dietary and supplemental folate and the risk of left- and right-sided colorectal cancer. Nutrition and cancer, 2012, Volume: 64, Issue:7 Topics: Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Dietary Supplements; Female; Folic Acid; Fruit; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Risk Factors; Surveys and Questionnaires; Western Australia	2012
Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study. Nutrition and cancer, 2012, Volume: 64, Issue:7 Topics: Aged; Colorectal Neoplasms; CpG Islands; DNA Methylation; Feeding Behavior; Female; Folic Acid; Follow-Up Studies; Genetic Markers; Humans; Incidence; Iowa; Life Style; Micronutrients; Microsatellite Instability; Middle Aged; Multivariate Analysis; Mutation; Nutrition Surveys; Phenotype; Proportional Hazards Models; Prospective Studies; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); ras Proteins; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Women's Health	2012
Following up folate and its function in colorectal carcinogenesis. Journal of the National Cancer Institute, 2012, Oct-17, Volume: 104, Issue:20 Topics: Adenoma; Anticarcinogenic Agents; Cardiovascular Diseases; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Vitamin B 12; Vitamin B 6	2012
[Chemoprevention of colorectal cancer associated with IBD]. Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 1 Topics: Azathioprine; Colorectal Neoplasms; Crohn Disease; Folic Acid; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine	2012
Plasma B vitamins and LINE-1 DNA methylation in leukocytes of patients with a history of colorectal adenomas. Molecular nutrition & food research, 2013, Volume: 57, Issue:4 Topics: Adenoma; Adolescent; Adult; Aged; Colorectal Neoplasms; Cross-Sectional Studies; DNA Methylation; Female; Folic Acid; Follow-Up Studies; Genotype; Humans; Leukocytes; Life Style; Linear Models; Long Interspersed Nucleotide Elements; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Risk Factors; Surveys and Questionnaires; Vitamin B Complex; Young Adult	2013
Frequent epigenetic silencing of the folate-metabolising gene cystathionine-beta-synthase in gastrointestinal cancer. PloS one, 2012, Volume: 7, Issue:11 Topics: Cell Line, Tumor; Colorectal Neoplasms; Cystathionine beta-Synthase; DNA Methylation; Down-Regulation; Folic Acid; Gastrointestinal Neoplasms; Gene Silencing; Humans; Mutation; Neoplasm Metastasis; Neoplasm Staging; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Stomach Neoplasms	2012
B vitamin intakes and incidence of colorectal cancer: results from the Women's Health Initiative Observational Study cohort. The American journal of clinical nutrition, 2013, Volume: 97, Issue:2 Topics: Aged; Alcohol Drinking; Cohort Studies; Colorectal Neoplasms; Diet; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Food, Fortified; Humans; Incidence; Middle Aged; Proportional Hazards Models; Prospective Studies; Riboflavin; United States; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency	2013
Systemic folate status, rectal mucosal folate concentration and dietary intake in patients at differential risk of bowel cancer (The FAB2 Study). European journal of nutrition, 2013, Volume: 52, Issue:7 Topics: Cohort Studies; Colorectal Neoplasms; Diet; Erythrocytes; Female; Folic Acid; Glutathione Reductase; Homocysteine; Humans; Intestinal Mucosa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nutrition Assessment; Nutritional Status; Risk Factors; Surveys and Questionnaires; Tetrahydrofolates; Vitamin B 12	2013
Folate, methionine, alcohol, and colorectal cancer in a prospective study of women in the United States. Cancer causes & control : CCC, 2002, Volume: 13, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Cohort Studies; Colorectal Neoplasms; Feeding Behavior; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Hematinics; Humans; Methionine; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; United States	2002
Dietary folate and colorectal cancer. International journal of cancer, 2002, Dec-10, Volume: 102, Issue:5 Topics: Adult; Alcohol Drinking; Case-Control Studies; Colonic Neoplasms; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Rectal Neoplasms	2002
The role of folic acid and vitamin B12 in colorectal carcinogenesis in genetically different individuals--design of a study. IARC scientific publications, 2002, Volume: 156 Topics: Adenomatous Polyps; Case-Control Studies; Colorectal Neoplasms; DNA; DNA Methylation; Folic Acid; Gene Expression Regulation, Neoplastic; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oligonucleotide Array Sequence Analysis; Oxidoreductases Acting on CH-NH Group Donors; Research Design; Risk Factors; Tumor Cells, Cultured; Vitamin B 12	2002
Relationship of folate, vitamin B-6, vitamin B-12, and methionine intake to incidence of colorectal cancers. Nutrition and cancer, 2002, Volume: 43, Issue:2 Topics: Aged; Alcohol Drinking; Cohort Studies; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Humans; Incidence; Iowa; Methionine; Middle Aged; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6	2002
Biochemical and molecular aberrations in the rat colon due to folate depletion are age-specific. The Journal of nutrition, 2003, Volume: 133, Issue:4 Topics: Aging; Animals; Colon; Colorectal Neoplasms; DNA Methylation; Folic Acid; Folic Acid Deficiency; Male; Rats; Rats, Sprague-Dawley	2003
Relation of plasma folate and methylenetetrahydrofolate reductase C677T polymorphism to colorectal adenomas. International journal of epidemiology, 2003, Volume: 32, Issue:1 Topics: Adenoma; Case-Control Studies; Colorectal Neoplasms; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk	2003
Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study. Gastroenterology, 2003, Volume: 124, Issue:5 Topics: Adenoma; Aged; Case-Control Studies; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors	2003
Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer. Cancer research, 2003, Jun-15, Volume: 63, Issue:12 Topics: Aged; Alcohol Drinking; Ascorbic Acid; Cocarcinogenesis; Cohort Studies; Colorectal Neoplasms; Diet; Dietary Fiber; DNA Methylation; DNA, Neoplasm; Dose-Response Relationship, Drug; Energy Intake; Ethanol; Feeding Behavior; Female; Folic Acid; Folic Acid Deficiency; Gene Silencing; Humans; Iron, Dietary; Male; Middle Aged; Netherlands; Pilot Projects; Promoter Regions, Genetic; Risk Factors	2003
Effects of dietary folate and aging on gene expression in the colonic mucosa of rats: implications for carcinogenesis. Carcinogenesis, 2004, Volume: 25, Issue:1 Topics: Aging; Animals; Colon; Colorectal Neoplasms; Diet; Folic Acid; Gene Expression Regulation; Intestinal Mucosa; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligonucleotide Probes; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53; Urokinase-Type Plasminogen Activator	2004
Multivitamin use and colorectal cancer incidence in a US cohort: does timing matter? American journal of epidemiology, 2003, Oct-01, Volume: 158, Issue:7 Topics: Aged; Aged, 80 and over; Cohort Studies; Colorectal Neoplasms; Dietary Supplements; Feeding Behavior; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Life Style; Male; Middle Aged; Risk Assessment; Socioeconomic Factors; Time Factors; United States; Vitamins	2003
Effects of dietary folate on ulcerative colitis-associated colorectal carcinogenesis in the interleukin 2- and beta(2)-microglobulin-deficient mice. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:11 Pt 1 Topics: Animals; beta 2-Microglobulin; Cell Transformation, Neoplastic; Colitis, Ulcerative; Colorectal Neoplasms; Diet; Dietary Supplements; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Humans; Interleukin-2; Mice; Mice, Inbred C57BL	2003
Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Dec-01, Volume: 9, Issue:16 Pt 1 Topics: Aged; Colon; Colorectal Neoplasms; Female; Folic Acid; gamma-Glutamyl Hydrolase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; Membrane Transport Proteins; Peptide Synthases; Prognosis; Rectum; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Thymidylate Synthase	2003
Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenoma; Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Genotype; Humans; Logistic Models; Male; Middle Aged; Minnesota; Polymorphism, Genetic; Risk Factors; Sex Distribution	2004
[Chemopreventive agents in colorectal cancer]. La Revue du praticien, 2003, Dec-31, Volume: 53, Issue:20 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Controlled Clinical Trials as Topic; Cyclooxygenase Inhibitors; Female; Folic Acid; Follow-Up Studies; Hematinics; Humans; Middle Aged; Multicenter Studies as Topic; Placebos; Prospective Studies; Risk; Risk Factors; Time Factors	2003
Folate and colorectal neoplasia: relation between plasma and dietary markers of folate and adenoma recurrence. The American journal of clinical nutrition, 2004, Volume: 79, Issue:4 Topics: Adenoma; Adult; Aged; Colorectal Neoplasms; Diet; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Neoplasm Recurrence, Local; Risk Factors; Surveys and Questionnaires	2004
Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium. The Journal of nutrition, 2004, Volume: 134, Issue:4 Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; DNA; DNA Methylation; Epithelium; Folic Acid; Gas Chromatography-Mass Spectrometry; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Uracil; Vitamin B 12; Vitamin B 12 Deficiency	2004
XRCC2 and XRCC3 polymorphisms are not associated with risk of colorectal adenoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:6 Topics: Adenoma; Alcohol Drinking; Case-Control Studies; Colorectal Neoplasms; DNA-Binding Proteins; Folic Acid; Genotype; Humans; Logistic Models; Nurses; Polymorphism, Genetic; Risk Factors; Smoking	2004
Folate intake, MTHFR C677T polymorphism, alcohol consumption, and risk for sporadic colorectal adenoma (United States). Cancer causes & control : CCC, 2004, Volume: 15, Issue:5 Topics: Adenoma; Adult; Aged; Alcohol Drinking; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors	2004
Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; DNA Damage; DNA Methylation; Erythrocytes; Female; Folic Acid; Genetic Carrier Screening; Genetic Variation; Genotype; Homocysteine; Homozygote; Humans; Isoenzymes; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Scotland; Tetrahydrofolates; Uracil; Vitamin B 12	2004
Dietary factors and truncating APC mutations in sporadic colorectal adenomas. International journal of cancer, 2005, Jan-01, Volume: 113, Issue:1 Topics: Adenoma; Adult; Aged; Alcohol Drinking; Animals; Ascorbic Acid; beta Carotene; Calcium, Dietary; Case-Control Studies; Colorectal Neoplasms; Dairy Products; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; DNA, Neoplasm; Edible Grain; Energy Intake; Feeding Behavior; Female; Fishes; Folic Acid; Fruit; Genes, APC; Humans; Male; Meat; Middle Aged; Mutation; Netherlands; Poultry; Sequence Analysis, DNA; Vegetables	2005
[Ulcerative colitis. Cancer prevention]. Zeitschrift fur Gastroenterologie, 2004, Volume: 42, Issue:9 Topics: Adenoma; Adenomatous Polyposis Coli; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Case-Control Studies; Child; Cholagogues and Choleretics; Cholangitis, Sclerosing; Colectomy; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Cross-Sectional Studies; Female; Folic Acid; Follow-Up Studies; Humans; Male; Meta-Analysis as Topic; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Ursodeoxycholic Acid	2004
Lethal toxicity after 5-fluorouracil chemotherapy and its possible relationship to dihydropyrimidine dehydrogenase deficiency: a case report and review of the literature. Journal of chemotherapy (Florence, Italy), 2004, Volume: 16, Issue:6 Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Deficiency Diseases; Dihydropyrimidine Dehydrogenase Deficiency; Fatal Outcome; Female; Fluorouracil; Folic Acid; Humans; Middle Aged	2004
Reversal of DNA hypomethylation by folic acid supplements: possible role in colorectal cancer prevention. Gut, 2005, Volume: 54, Issue:5 Topics: Biomarkers; Colorectal Neoplasms; Dietary Supplements; Disease Susceptibility; DNA Methylation; DNA, Neoplasm; Folic Acid; Humans; Risk Factors	2005
The MTHFR C677T polymorphism and colorectal cancer: the multiethnic cohort study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:5 Topics: Aged; Alcohol Drinking; Alleles; Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Diet Surveys; Ethnicity; Female; Folic Acid; Gene Frequency; Genotype; Hawaii; Humans; Los Angeles; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Genetic	2005
Is the association with fiber from foods in colorectal cancer confounded by folate intake? Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:6 Topics: Cohort Studies; Colorectal Neoplasms; Confounding Factors, Epidemiologic; Diet; Dietary Fiber; Female; Folic Acid; Functional Laterality; Humans; Male; Middle Aged; Multivariate Analysis	2005
Dietary intake of folate and riboflavin, MTHFR C677T genotype, and colorectal adenoma risk: a Dutch case-control study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:6 Topics: Adenoma; Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Netherlands; Polymorphism, Genetic; Riboflavin	2005
Colorectal cancer: influence of diet and lifestyle factors. Revista espanola de enfermedades digestivas, 2005, Volume: 97, Issue:6 Topics: Alcohol Drinking; Antioxidants; Calcium; Case-Control Studies; Colorectal Neoplasms; Diet; Dietary Fats; Dietary Fiber; Dietary Supplements; Exercise; Folic Acid; Fruit; Humans; Life Style; Meat; Prospective Studies; Risk Factors; Smoking; Vegetables	2005
One-carbon metabolism related gene polymorphisms interact with alcohol drinking to influence the risk of colorectal cancer in Japan. Carcinogenesis, 2005, Volume: 26, Issue:12 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alcohol Drinking; Carbon; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genotype; Humans; Japan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk Factors; Thymidylate Synthase	2005
Nutrigenetics in cancer research--folate metabolism and colorectal cancer. The Journal of nutrition, 2005, Volume: 135, Issue:11 Topics: Colorectal Neoplasms; Diet; DNA Methylation; Folic Acid; Genetic Predisposition to Disease; Humans; Nutritional Physiological Phenomena; Pharmacogenetics; Polymorphism, Genetic	2005
Treatment of advanced colorectal and gastric cancer with 5-fluorouracil and calcium n-methyltetrahydrofolate. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Stomach Neoplasms; Treatment Outcome	1989
A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan. Carcinogenesis, 2006, Volume: 27, Issue:5 Topics: Adult; Aged; Alcohol Dehydrogenase; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Japan; Male; Middle Aged; Polymorphism, Genetic; Risk	2006
Folate levels and cancer morbidity and mortality: prospective cohort study from Busselton, Western Australia. Annals of epidemiology, 2006, Volume: 16, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Australia; Breast Neoplasms; Cohort Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Morbidity; Mortality; Neoplasms; Prospective Studies; Prostatic Neoplasms	2006
Folate, vitamin B6, vitamin B12, and vitamin B2 intake, genetic polymorphisms of related enzymes, and risk of colorectal cancer in a hospital-based case-control study in Japan. Nutrition and cancer, 2005, Volume: 53, Issue:1 Topics: Adult; Aged; Aldehyde Dehydrogenase; Carbon-Nitrogen Ligases; Case-Control Studies; Colorectal Neoplasms; Diet; Dietary Fiber; DNA Methylation; Female; Ferredoxin-NADP Reductase; Folic Acid; Humans; Japan; Logistic Models; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Riboflavin; Risk Factors; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2005
Relationship between nutritional habits adopted by ulcerative colitis relevant to cancer development patients at clinical remission stages and molecular-genetic parameters. The British journal of nutrition, 2006, Volume: 95, Issue:1 Topics: Adult; Aged; Aneuploidy; Ascorbic Acid; Calcium, Dietary; Chromosomes, Human, Pair 17; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Dietary Fats; Dietary Fiber; Energy Intake; Fabaceae; Feeding Behavior; Female; Folic Acid; Genetic Predisposition to Disease; Humans; In Situ Hybridization, Fluorescence; Male; Middle Aged; Nutritional Status; Risk Factors; Vitamin A	2006
Expression and clinical significance of methylenetetrahydrofolate reductase in patients with colorectal cancer. Clinical colorectal cancer, 2006, Volume: 5, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Carcinoma; Colorectal Neoplasms; Female; Folic Acid; Gene Expression; Humans; Intestinal Mucosa; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; RNA, Messenger; Survival Rate	2006
Distinctive clinicopathological features of Ki-ras mutated colorectal cancers. Journal of surgical oncology, 2006, Sep-01, Volume: 94, Issue:3 Topics: Aged; Calcium; Chi-Square Distribution; Colorectal Neoplasms; DNA Mutational Analysis; Female; Folic Acid; Gene Frequency; Genes, ras; Humans; Male; Middle Aged; Mutation; Neoplasm Invasiveness; Neoplasm Staging; Prognosis	2006
What if it were fruit or vegetables? Harvard health letter, 2006, Volume: 31, Issue:10 Topics: Colorectal Neoplasms; Folic Acid; Fruit; Humans; Intestinal Polyps; Vegetables	2006
Localized depletion: the key to colorectal cancer risk mediated by MTHFR genotype and folate? Cancer causes & control : CCC, 2006, Volume: 17, Issue:8 Topics: Colorectal Neoplasms; DNA; DNA Methylation; Enzyme Stability; Ethnicity; Folic Acid; Folic Acid Deficiency; Gene Frequency; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Polymorphism, Single Nucleotide; Risk Factors	2006
Role of MTHFR polymorphisms and folate levels in different phenotypes of sporadic colorectal cancers. International journal of colorectal disease, 2007, Volume: 22, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Aneuploidy; Case-Control Studies; Chromosomal Instability; Colorectal Neoplasms; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Microsatellite Instability; Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Taiwan; Vitamin B 12	2007
Folate: a magic bullet or a double edged sword for colorectal cancer prevention? Gut, 2006, Volume: 55, Issue:10 Topics: Colorectal Neoplasms; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Humans; Risk Factors	2006
Folate metabolism polymorphisms influence risk of colorectal adenoma recurrence. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:9 Topics: Adenoma; Adult; Aged; Colorectal Neoplasms; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Polymorphism, Genetic; Risk	2006
Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention. Journal of the National Cancer Institute, 2006, Oct-18, Volume: 98, Issue:20 Topics: Adenoma; Adenomatous Polyposis Coli; Aged; Alanine; Anticarcinogenic Agents; Aspirin; Colorectal Neoplasms; Female; Folic Acid; Gastrointestinal Agents; Gene Frequency; Genotype; Glycine; Humans; Male; Middle Aged; Ornithine Decarboxylase; Polymorphism, Single Nucleotide; Racial Groups; Randomized Controlled Trials as Topic; Risk Assessment	2006
Global DNA and p53 region-specific hypomethylation in human colonic cells is induced by folate depletion and reversed by folate supplementation. The Journal of nutrition, 2006, Volume: 136, Issue:11 Topics: Azacitidine; Cell Line, Tumor; Colorectal Neoplasms; Comet Assay; DNA Methylation; Folic Acid; Folic Acid Deficiency; Genes, p53; Humans	2006
Dietary factors and biomarkers involved in the methylenetetrahydrofolate reductase genotype-colorectal adenoma pathway. Gastroenterology, 2006, Volume: 131, Issue:6 Topics: Adenoma; Aged; Biomarkers, Tumor; Carbon; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; Female; Folic Acid; Genotype; Homeostasis; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Polymorphism, Genetic; Prospective Studies; Risk Factors; Vitamins	2006
Dietary intake of B-vitamins, polymorphisms in thymidylate synthase and serine hydroxymethyltransferase 1, and colorectal adenoma risk: a Dutch case-control study. Cancer letters, 2007, May-18, Volume: 250, Issue:1 Topics: Adenoma; Aged; Case-Control Studies; Colorectal Neoplasms; Diet; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Middle Aged; Netherlands; Polymorphism, Genetic; Riboflavin; Risk Factors; Thymidylate Synthase; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2007
Dietary folate and APC mutations in sporadic colorectal cancer. The Journal of nutrition, 2006, Volume: 136, Issue:12 Topics: Adaptor Proteins, Signal Transducing; Aged; Carrier Proteins; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Diet; DNA, Neoplasm; Female; Folic Acid; Genes, APC; Humans; Male; Middle Aged; Mutation; MutL Protein Homolog 1; Nuclear Proteins; Patient Selection; Proportional Hazards Models; Rectal Neoplasms; Surveys and Questionnaires	2006
Colorectal cancer protective effects and the dietary micronutrients folate, methionine, vitamins B6, B12, C, E, selenium, and lycopene. Nutrition and cancer, 2006, Volume: 56, Issue:1 Topics: Antioxidants; Ascorbic Acid; Carotenoids; Case-Control Studies; Colorectal Neoplasms; Diet; Diet Surveys; DNA Methylation; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Lycopene; Male; Methionine; Micronutrients; Odds Ratio; Risk Factors; Selenium; Survival Analysis; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin E; Vitamins	2006
Folate and colorectal cancer: an evidence-based critical review. Molecular nutrition & food research, 2007, Volume: 51, Issue:3 Topics: Animals; Chemoprevention; Colorectal Neoplasms; Diet; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Folic Acid Deficiency; Humans; Precancerous Conditions; Risk Factors	2007
Dietary folate intake in combination with MTHFR C677T genotype and promoter methylation of tumor suppressor and DNA repair genes in sporadic colorectal adenomas. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:2 Topics: Adenoma; Adolescent; Adult; Aged; Case-Control Studies; Colorectal Neoplasms; DNA Methylation; DNA Repair; Female; Folic Acid; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Genotype; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Netherlands; Polymerase Chain Reaction; Promoter Regions, Genetic; Surveys and Questionnaires	2007
MTHFR C677T has differential influence on risk of MSI and MSS colorectal cancer. Human molecular genetics, 2007, May-01, Volume: 16, Issue:9 Topics: Adult; Aged; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genomic Instability; Genotype; Germ-Line Mutation; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Microsatellite Repeats; Middle Aged; Phenotype; Polymorphism, Single Nucleotide	2007
[Benefits of TS-1 plus leucovorin combination therapy for colorectal cancer: evaluation of therapeutic effect of TS-1 and leucovorin combination therapy using rodent model fed a low folate diet]. Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diet; Disease Models, Animal; Drug Combinations; Drug Evaluation; Folic Acid; Humans; Leucovorin; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oxonic Acid; Tegafur	2007
Folate status and risk of colorectal polyps in African Americans. Digestive diseases and sciences, 2007, Volume: 52, Issue:6 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Black or African American; Case-Control Studies; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Genes, APC; Homocysteine; Humans; Male; Middle Aged; Promoter Regions, Genetic; Smoking; Tetrahydrofolates; Vitamin B 12; Vitamins	2007
Folate status and S-adenosylmethionine/S-adenosylhomocysteine ratio in colorectal adenocarcinoma in humans. European journal of clinical nutrition, 2008, Volume: 62, Issue:2 Topics: Adenocarcinoma; Aged; Colon; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine	2008
Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the Nurses' Health Study. Carcinogenesis, 2007, Volume: 28, Issue:7 Topics: Adenoma; Adult; Alcohol Drinking; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetics, Population; Humans; Methionine; Middle Aged; One-Carbon Group Transferases; Polymorphism, Single Nucleotide; Prospective Studies; Risk; Transcobalamins; Vitamin B 12	2007
Folate and cancer--timing is everything. JAMA, 2007, Jun-06, Volume: 297, Issue:21 Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Folic Acid; Humans; Neoplasms; Risk; Treatment Failure	2007
Low intake of vitamin B-6 is associated with increased risk of colorectal cancer in Japanese men. The Journal of nutrition, 2007, Volume: 137, Issue:7 Topics: Aged; Alcoholic Beverages; Colorectal Neoplasms; Diet; Diet Surveys; Female; Folic Acid; Follow-Up Studies; Humans; Japan; Male; Methionine; Middle Aged; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6	2007
A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:7 Topics: Animals; Canada; Colorectal Neoplasms; Folic Acid; Food, Fortified; Humans; Incidence; Neural Tube Defects; United States	2007
Commentary: a case for minimizing folate supplementation in clinical regimens with pemetrexed based on the marked sensitivity of the drug to folate availability. The oncologist, 2007, Volume: 12, Issue:7 Topics: Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Colorectal Neoplasms; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; In Vitro Techniques; Lung Neoplasms; Mesothelioma; Pemetrexed; Tetrahydrofolates	2007
[Nutritional and antioxidant status of colorectal cancer patients]. Orvosi hetilap, 2007, Aug-12, Volume: 148, Issue:32 Topics: Adenoma; Aged; Antioxidants; Biomarkers; Carcinoma; Case-Control Studies; Colorectal Neoplasms; Dietary Fiber; Female; Folic Acid; Free Radical Scavengers; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Middle Aged; Nutritional Status; Obesity; Overweight; Prealbumin; Vitamin A	2007
Folic Acid supplements do not appear to reduce risk of colorectal tumors. Gastroenterology, 2007, Volume: 133, Issue:2 Topics: Adenoma; Anticarcinogenic Agents; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Risk Assessment; Risk Factors; Vitamin B Complex	2007
One-carbon metabolism, colorectal carcinogenesis, chemoprevention--with caution. Journal of the National Cancer Institute, 2007, Aug-15, Volume: 99, Issue:16 Topics: Animals; Betaine; Carbon; Cell Transformation, Neoplastic; Chemoprevention; Choline; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine	2007
Folate and colo-rectal cancer risk. The British journal of nutrition, 2007, Volume: 98, Issue:6 Topics: Colorectal Neoplasms; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Food, Fortified; Government Agencies; Humans; Risk Assessment; United Kingdom	2007
Folic acid and prevention of colorectal adenomas. JAMA, 2007, Sep-26, Volume: 298, Issue:12 Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Folic Acid; Humans; Risk; Vitamin B Complex	2007
Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia. The American journal of clinical nutrition, 2007, Volume: 86, Issue:4 Topics: Adaptor Proteins, Signal Transducing; Adenoma; Aged; Base Sequence; Biomarkers; Case-Control Studies; Colon; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Estrogen Receptor alpha; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; MutL Protein Homolog 1; Nuclear Proteins; Nutritional Status; Vitamin B 12	2007
Plasma folate and risk of colorectal cancer in a nested case-control study: the Japan Public Health Center-based prospective study. Cancer causes & control : CCC, 2008, Volume: 19, Issue:1 Topics: Adult; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Japan; Male; Prospective Studies; Public Health; Sex Factors	2008
Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenoma. British journal of cancer, 2007, Nov-19, Volume: 97, Issue:10 Topics: Adenoma; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Surveys and Questionnaires; Thymidylate Synthase; Vitamin B Complex	2007
Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer: a case-control study in a population with relatively low folate intake. The British journal of nutrition, 2008, Volume: 99, Issue:2 Topics: Adult; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 6	2008
Folic acid fortification and cancer risk. Lancet (London, England), 2007, Dec-15, Volume: 370, Issue:9604 Topics: Adenoma; Canada; Colorectal Neoplasms; Folic Acid; Food, Fortified; Humans; Incidence; Neural Tube Defects; Risk Factors; United States	2007
Plasma vitamin B12 concentrations and the risk of colorectal cancer: a nested case-referent study. International journal of cancer, 2008, May-01, Volume: 122, Issue:9 Topics: Adult; Aged; Analysis of Variance; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Assessment; Risk Factors; Sweden; Vitamin B 12	2008
Chemoprevention for colorectal cancer: some progress but a long way to go. Gastroenterology, 2008, Volume: 134, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Folic Acid; Hematinics; Humans; Neoplasm Recurrence, Local; Risk Factors	2008
Folate and MTHFR: risk of adenoma recurrence in the Polyp Prevention Trial. Cancer causes & control : CCC, 2008, Volume: 19, Issue:7 Topics: Adenoma; Aged; Alleles; Colorectal Neoplasms; Female; Folic Acid; Follow-Up Studies; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Odds Ratio; Surveys and Questionnaires; Vitamin B Complex	2008
Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer. Carcinogenesis, 2008, Volume: 29, Issue:9 Topics: Adaptor Proteins, Signal Transducing; Aged; Cohort Studies; Colorectal Neoplasms; Diet; DNA Methylation; DNA, Neoplasm; Female; Folic Acid; Humans; Male; Methionine; Microsatellite Repeats; Middle Aged; Mutation; MutL Protein Homolog 1; Netherlands; Nuclear Proteins; Phenotype; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Riboflavin; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6	2008
Low expression of gamma-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype. British journal of cancer, 2008, May-06, Volume: 98, Issue:9 Topics: Adult; Aged; Colorectal Neoplasms; CpG Islands; DNA Methylation; Down-Regulation; Female; Folic Acid; gamma-Glutamyl Hydrolase; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Middle Aged; Nucleotides; Phenotype; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2008
Folic acid fortification and cancer risk. Lancet (London, England), 2008, Apr-19, Volume: 371, Issue:9621 Topics: Colorectal Neoplasms; Folic Acid; Food, Fortified; Hematinics; Humans; Vitamin B Complex	2008
Folic acid fortification and cancer risk. Lancet (London, England), 2008, Apr-19, Volume: 371, Issue:9621 Topics: Colorectal Neoplasms; Folic Acid; Genes, p16; Genotype; Hematinics; Humans; Risk	2008
Systemic folate status and risk of colorectal cancer. Cancer causes & control : CCC, 2008, Volume: 19, Issue:9 Topics: Colorectal Neoplasms; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Risk	2008
[Therapy of colorectal carcinoma. To combine saves lives]. MMW Fortschritte der Medizin, 2004, Jan-15, Volume: 146, Issue:1-2 Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Folic Acid; Humans; Multicenter Studies as Topic; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Randomized Controlled Trials as Topic; Time Factors; Vitamin B Complex	2004
Aspirin helps prevent recurring colorectal adenomas--folic acid does not. Medscape journal of medicine, 2008, Mar-20, Volume: 10, Issue:3 Topics: Adenoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemotherapy, Adjuvant; Colonoscopy; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Hematinics; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Randomized Controlled Trials as Topic	2008
Dairy products, polymorphisms in the vitamin D receptor gene and colorectal adenoma recurrence. International journal of cancer, 2008, Aug-01, Volume: 123, Issue:3 Topics: Adenoma; Adult; Aged; Animals; Aspirin; Calcium Compounds; Colorectal Neoplasms; Dairy Products; Female; Folic Acid; Humans; Male; Middle Aged; Milk; Neoplasm Recurrence, Local; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Receptors, Calcitriol; Risk Assessment; Risk Factors; Surveys and Questionnaires; Transcription Factors; United Kingdom; Vitamin D	2008
Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats. The American journal of clinical nutrition, 1995, Volume: 61, Issue:5 Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; DNA; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Genes, myc; Liver; Male; Methionine; Methylation; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine	1995
Selected micronutrient intake and the risk of colorectal cancer. British journal of cancer, 1994, Volume: 70, Issue:6 Topics: Adult; Age Factors; Aged; Ascorbic Acid; beta Carotene; Carotenoids; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Middle Aged; Regression Analysis; Risk Factors; Sex Factors; Vitamin E	1994
Ternary complex formation and reduced folate in surgical specimens of human adenocarcinoma tissues. Cancer, 1993, Jan-15, Volume: 71, Issue:2 Topics: Adenocarcinoma; Colorectal Neoplasms; Culture Techniques; Fluorouracil; Folic Acid; Humans; Leucovorin; Lymph Nodes; Phosphorylation; Stomach Neoplasms; Tetrahydrofolates; Thymidine Kinase; Thymidylate Synthase	1993
[Changes of the number of FdUMP binding sites of thymidylate synthase and folate pools in human colorectal carcinomas following the administration of tegafur and uracil: preliminary report]. Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Binding Sites; Colorectal Neoplasms; Fluorodeoxyuridylate; Folic Acid; Humans; Tegafur; Thymidylate Synthase; Uracil	1993
Folate, methionine, and alcohol intake and risk of colorectal adenoma. Journal of the National Cancer Institute, 1993, Jun-02, Volume: 85, Issue:11 Topics: Adenoma; Adult; Aged; Alcohol Drinking; Colorectal Neoplasms; Feeding Behavior; Female; Folic Acid; Humans; Male; Methionine; Methylation; Middle Aged; Prevalence; Prospective Studies; Proto-Oncogene Mas; Risk; Surveys and Questionnaires	1993
Stereospecific pharmacokinetics of rac-5-methyltetrahydrofolic acid in patients with advanced colorectal cancer. British journal of clinical pharmacology, 1995, Volume: 40, Issue:3 Topics: Aged; Binding, Competitive; Colorectal Neoplasms; Female; Folic Acid; Folic Acid Antagonists; Humans; Injections, Intravenous; Male; Middle Aged; Pharmacokinetics; Time Factors	1995
Pre-operative interleukin-2 immunotherapy induces eosinophilic infiltration in colorectal neoplastic stroma. Pathologica, 1995, Volume: 87, Issue:2 Topics: Adult; Antineoplastic Agents; Carcinoma; Chemotaxis, Leukocyte; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Connective Tissue; Eosinophilia; Eosinophils; Female; Fluorouracil; Folic Acid; Humans; Immunologic Factors; Immunotherapy; Interleukin-2; Leukocyte Count; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Premedication; Prognosis; Recombinant Proteins; Treatment Outcome	1995
Colorectal cancer and folate status: a nested case-control study among male smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1996, Volume: 5, Issue:7 Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Confidence Intervals; Finland; Folic Acid; Humans; Incidence; Logistic Models; Male; Middle Aged; Risk Factors; Sensitivity and Specificity; Smoking	1996
Exon-specific DNA hypomethylation of the p53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate. The American journal of pathology, 1996, Volume: 149, Issue:4 Topics: Animals; Colon; Colorectal Neoplasms; Disease Models, Animal; DNA Methylation; Exons; Folic Acid; Genes, p53; Male; Monomethylhydrazine; Precancerous Conditions; Rats; Rats, Sprague-Dawley	1996
A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer. Cancer research, 1996, Nov-01, Volume: 56, Issue:21 Topics: Adult; Aged; Colorectal Neoplasms; Ethanol; Folic Acid; Genotype; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Risk Factors	1996
Folate and alcohol intakes: related or independent roles in the adenoma-carcinoma sequence? Nutrition and cancer, 1996, Volume: 26, Issue:3 Topics: Adenoma; Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Drug Interactions; Ethanol; Female; Folic Acid; Humans; Male; Middle Aged; Odds Ratio; Risk Factors	1996
Micronutrients and the risk of colorectal adenomas. American journal of epidemiology, 1996, Dec-01, Volume: 144, Issue:11 Topics: Adenoma; Calcium, Dietary; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Iron; Male; Micronutrients; Middle Aged; Odds Ratio; Risk; Vitamins	1996
Levels of folic acid in plasma and in red blood cells of colorectal cancer patients. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1996, Volume: 50, Issue:6-7 Topics: Aged; Aged, 80 and over; Colorectal Neoplasms; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged	1996
The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis. Gastroenterology, 1997, Volume: 112, Issue:1 Topics: Adult; Cohort Studies; Colitis, Ulcerative; Colorectal Neoplasms; Female; Folic Acid; Hematinics; Humans; Male; Odds Ratio; Precancerous Conditions; Risk Assessment	1997
Folate intake, alcohol consumption, cigarette smoking, and risk of colorectal adenomas. Journal of the National Cancer Institute, 1998, Jan-07, Volume: 90, Issue:1 Topics: Adenoma; Aged; Alcohol Drinking; Anticarcinogenic Agents; Clinical Trials as Topic; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Multicenter Studies as Topic; Risk; Risk Factors; Smoking	1998
Chemoprevention: a new way to face colorectal cancer in ulcerative colitis. Italian journal of gastroenterology and hepatology, 1998, Volume: 30, Issue:4 Topics: Colitis, Ulcerative; Colorectal Neoplasms; Folic Acid; Humans	1998
A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma. Carcinogenesis, 1998, Volume: 19, Issue:12 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenoma; Adult; Colorectal Neoplasms; Ethanol; Female; Folic Acid; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Risk Factors	1998
Serum folate, homocysteine and colorectal cancer risk in women: a nested case-control study. British journal of cancer, 1999, Volume: 79, Issue:11-12 Topics: Aged; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Multivariate Analysis; Risk Factors	1999
[Value of multivitamin preparations and folic acid in primary prevention of colonic cancer in women]. Zeitschrift fur Gastroenterologie, 1999, Volume: 37, Issue:6 Topics: Adenocarcinoma; Adult; Age Factors; Aged; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Diet; Dietary Fiber; Female; Folic Acid; Follow-Up Studies; Humans; Middle Aged; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Time Factors; Vitamins	1999
A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:9 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Canada; Case-Control Studies; Colorectal Neoplasms; Folic Acid; Genotype; Homocysteine; Humans; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors; Surveys and Questionnaires; United States; Vitamin B 12; White People	1999
Risk factors for Ki-ras protooncogene mutation in sporadic colorectal adenomas. Cancer research, 1999, Oct-15, Volume: 59, Issue:20 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Genes, ras; Humans; Male; Middle Aged; Mutation; Risk Factors	1999
Chronic alcohol consumption induces genomic but not p53-specific DNA hypomethylation in rat colon. The Journal of nutrition, 1999, Volume: 129, Issue:11 Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; Diet; DNA Methylation; Ethanol; Folic Acid; Genes, Tumor Suppressor; Genome; Male; Organ Size; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53	1999
The effect of dietary folate on Apc and p53 mutations in the dimethylhydrazine rat model of colorectal cancer. Carcinogenesis, 1999, Volume: 20, Issue:12 Topics: Animals; Base Sequence; Carcinogens; Colorectal Neoplasms; Dimethylhydrazines; Disease Models, Animal; DNA Primers; Folic Acid; Genes, APC; Genes, p53; Male; Mutation; Rats; Rats, Inbred F344; Rats, Sprague-Dawley	1999
[Nutrition, genetic polymorphism, and cancer]. Bulletin du cancer, 2000, Volume: 87, Issue:2 Topics: Colorectal Neoplasms; DNA; DNA Repair; Folic Acid; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Nutritional Physiological Phenomena; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Tetrahydrofolates; Thymidine; Uridine	2000
Chemopreventive effects of dietary folate on intestinal polyps in Apc+/-Msh2-/- mice. Cancer research, 2000, Jun-15, Volume: 60, Issue:12 Topics: Adenoma; Adenomatous Polyposis Coli Protein; Age Factors; Animals; Body Weight; Colon; Colorectal Neoplasms; CpG Islands; Cytoskeletal Proteins; Diet; DNA-Binding Proteins; Folic Acid; Intestinal Polyps; Intestine, Small; Methylation; Mice; Mice, Inbred C57BL; Microsatellite Repeats; MutS Homolog 2 Protein; Precancerous Conditions; Proto-Oncogene Proteins	2000
Folate deficiency reduces the development of colorectal cancer in rats. Carcinogenesis, 2000, Volume: 21, Issue:12 Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Folic Acid; Folic Acid Deficiency; Intestinal Neoplasms; Male; Rats; Rats, Sprague-Dawley	2000
Smoking, folate and methylenetetrahydrofolate reductase status as interactive determinants of adenomatous and hyperplastic polyps of colorectum. American journal of medical genetics, 2001, Jul-01, Volume: 101, Issue:3 Topics: Adenomatous Polyps; Aged; Colorectal Neoplasms; Cross-Sectional Studies; Female; Folic Acid; Gene Frequency; Genotype; Homocysteine; Humans; Hyperplasia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors; Smoking	2001
Targeted drug delivery to chemoresistant cells: folic acid derivatization of FdUMP[10] enhances cytotoxicity toward 5-FU-resistant human colorectal tumor cells. The Journal of organic chemistry, 2001, Aug-24, Volume: 66, Issue:17 Topics: Antineoplastic Agents; Carrier Proteins; Colorectal Neoplasms; Drug Delivery Systems; Drug Resistance, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Membrane Proteins; Membrane Transport Proteins; Receptors, Cell Surface; RNA, Messenger; Thymidylate Synthase; Tumor Cells, Cultured	2001
Dietary intake of folic acid and colorectal cancer risk in a cohort of women. International journal of cancer, 2002, Feb-20, Volume: 97, Issue:6 Topics: Body Mass Index; Canada; Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Diet; Folic Acid; Humans; Incidence; Methionine; Middle Aged; Risk Factors; Smoking	2002
Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas. Cancer research, 2002, Jun-15, Volume: 62, Issue:12 Topics: Adenoma; Adenomatous Polyps; Adult; Aged; Case-Control Studies; Colonoscopy; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Factors; Thymidylate Synthase	2002
A study of the pineal hormone melatonin as a second line therapy in metastatic colorectal cancer resistant to fluorouracil plus folates. Tumori, 1990, Feb-28, Volume: 76, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Drug Resistance; Female; Fluorouracil; Folic Acid; Humans; Male; Melatonin; Middle Aged; Neoplasm Metastasis	1990