Page last updated: 2024-08-17

folic acid and Cognitive Decline

folic acid has been researched along with Cognitive Decline in 97 studies

Research

Studies (97)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	52 (53.61)	24.3611
2020's	45 (46.39)	2.80

Authors

Authors	Studies
Montero-Bravo, A; Partearroyo, T; Puga, AM; Ruperto, M; Samaniego-Vaesken, ML; Varela-Moreiras, G	1
de Jager, CA; Frankowski, M; Jakubowski, H; Perła-Kaján, J; Refsum, H; Smith, AD; Zioła-Frankowska, A	1
Chen, ZY; Liang, H; Ma, AG; Ma, WJ; Wang, QZ; Zheng, Y	1
Gu, LY; Guo, Y; Li, P; Liu, S; Lu, R; Lu, Y; Pan, S; Pang, H; Xie, K; Yu, L; Zang, X; Zeng, X; Zhang, W; Zhou, Y	1
Clarke, R; De Looze, C; Kenny, RA; Laird, E; McGarrigle, CA; Molloy, AM; O'Connor, DMA; O'Halloran, AM; Scarlett, S	1
Cao, Y; Chen, X; Huang, Y; Wang, X; Yan, S; Yang, J; Yuan, C; Zhang, H; Zheng, Y; Zong, G	1
Fang, F; Fang, Z; Li, J; Li, X; Li, Y; Wang, J; Wang, X	1
Green, R; Miller, JW	1
Enomoto, S; Hamano, T; Ikawa, M; Ito, T; Kimura, H; Kimura, Y; Kuriyama, M; Nagata, M; Nakamoto, Y; Shirafuji, N; Ueno, A; Yamamura, O; Yamanaka, D	1
Cunnane, SC; Inzitari, M; Olaso-Gonzalez, G; Swerdlow, RH; Viña, J	1
Chen, Y; Du, Y; Duan, H; Fu, J; Huang, G; Huang, L; Li, W; Li, Z; Liu, H; Liu, Q; Ma, F; Sun, C; Wang, G; Wang, Z; Zhang, X; Zhao, J; Zhou, D; Zhu, Y	1
Cicognola, C; Frölich, K; Londos, E; Nyholm, E; Torkpoor, R	1
Gong, X; Kwok, T; Luo, Y; Shi, L; Wu, Y	1
Cheong, CY; Chong, MS; Gao, Q; Gwee, X; Lee, TS; Liew, TM; Lim, WS; Ng, TP; Przybycien-Gaweda, PM; Rawtaer, I; Yap, KB; Yap, P	1
Jia, J; Li, T; Quan, M; Song, Y	1
Adarmes-Gómez, AD; Bonilla-Toribio, M; Buiza-Rueda, D; Gómez-Garre, P; Jesús, S; Jimenez-Jaraba, MV; Macías-García, D; Martín-Rodríguez, JF; Mir, P; Muñoz-Delgado, L; Periñán, MT	1
Chang, CC; Chang, HI; Hsiao, HT; Hsu, SW; Huang, CW; Huang, SH; Lee, CC; Lin, CH; Ma, MC	1
Gu, Z; Hou, Z; Li, B; Liu, T; Lv, Q; Ruan, M; Yu, Q; Yu, X; Zhang, K; Zhang, T; Zhao, J	1
Cui, L; Guo, Q; Guo, Y; Huang, G; Huang, L; Jiang, X	1
Kenny, RA; Laird, E; Molloy, AM; O'Connor, D; O'Halloran, AM	1
Dong, C; Huang, G; Li, W; Li, Z; Qian, Z; Sun, Y; Wang, Z; Zhang, D; Zhao, J; Zhou, D	1
Avila-Nava, A; Chávez-Loría, G; Garrido-Dzib, AG; Gutiérrez-Solis, AL; Magallón-Zertuche, V; Palacios-González, B	1
Gou, M; Guo, X; Liu, Y	1
An, P; Chen, H; Du, Y; Gao, Y; Huang, G; Ji, Y; Liu, S; Lv, X; Ma, F; Song, A; Sun, C; Wang, G; Wang, X; Xu, W; Zhao, J; Zhou, X	1
Clarke, J; Dutta, E; Sahyoun, NR; Shao, K; Wang, B	1
An, Y; Feng, L; Qin, Z; Tao, L; Wang, Y; Xiao, R; Zhang, X	1
Scarmeas, N; Vlachos, GS	1
Chang, H; Huang, G; Li, W; Lv, X; Wang, X; Wang, Y; Wilson, JX; Zhou, D	1
Guo, J; Li, Y; Meng, H; Niu, X; Zhang, W; Zhao, Y	1
Choi, G; Harrison, J; Kwok, T; Lam, L; Lee, J; Lee, R; Lee, V; Mok, V; Wu, Y; Yung, CY	1
Grosso, G	1
Behrens, A; Donath, C; Graessel, E; Pendergrass, A	1
Ding, D; Luo, J; Yuan, C; Zhang, C	1
Bai, D; Chen, Y; Du, Y; Gao, Y; Huang, G; Li, M; Li, W; Liu, H; Ma, F; Wang, X; Weng, J	1
Alberto, JM; Bossenmeyer-Pourié, C; Daval, JL; Guéant, JL; Martin, N; Pourié, G; Umoret, R	1
Jiang, B; Yao, C; Yao, G; Zheng, N	1
Barreto, SM; Bensenor, IM; Fedeli, LMG; Liu, S; Lotufo, PA; Santos, IS; Suemoto, CK; ValladÃo-Junior, JBR	1
Gabelli, C; Reffo, A	1
Chen, Y; Du, Y; Fu, J; Huang, G; Jin, M; Li, W; Lin, H; Liu, H; Liu, Q; Ma, F; Sun, C; Wang, G; Yan, J; Zhang, M; Zhu, Y	1
Blasko, I; Defrancesco, M; Humpel, C; Kemmler, G; Loacker, L; Marksteiner, J; Oberacher, H	1
Feng, X; Hu, J; Hua, F; Xu, G; Zhan, F	1
Chen, Y; Du, Y; Fu, J; Huang, G; Jin, M; Li, W; Lin, H; Liu, H; Liu, Q; Ma, F; Sun, C; Sun, Z; Wang, G; Zhang, X	1
Bai, D; Dong, C; Fan, J; Fu, M; Gao, Y; Huang, G; Li, M; Liu, H	1
Bokova, IA; Shavlovskaya, OA; Shavlovskiy, NI; Yukhnovskaya, YD	1
de Jager, CA; Frankowski, M; Jakubowski, H; Perła-Kaján, J; Refsum, H; Smith, AD; Włoczkowska, O; Zioła-Frankowska, A	1
Bagio, E; Barichello, T; Bernades, G; Bonfante, S; da Rosa, N; de Oliveira Junior, AN; Fortunato, JJ; Garbossa, L; Generoso, J; Goldim, MP; Joaquim, L; Lanzzarin, E; Machado, RS; Mathias, K; Metzker, K; Novochadlo, M; Petronilho, F	1
Huang, G; Li, W; Liu, H; Luo, S; Lv, X; Wang, Y; Zhou, D	1
Jia, J; Tang, Y; Wang, Z; Xing, Y; Zhu, W	1
Gaudreau, P; Gougeon, L; Gray-Donald, K; Morais, JA; Payette, H; Shatenstein, B	1
Andel, R; Handing, EP; Kumar, N; McEvoy, CL; Small, BJ	1
Liu, Y; Qin, M; Shao, LQ; Sun, ZW; Wang, T; Weng, X; Xu, XB; Zhang, YX	1
Berrett, AN; Brown, BL; Erickson, LD; Gale, SD; Hedges, DW	1
Granic, A; Hill, TR; Jagger, C; Martin-Ruiz, C; Mathers, JC; Mendonça, N; Seal, CJ; Wesnes, KA	1
Huang, G; Ji, L; Ma, F; Song, A; Wu, T; Zhang, M; Zhao, J	1
Chang, HM; Chen, CLH; Earnest, A; Hameed, S; Li, H; Tan, EK; Ting, SKS	1
Absalom, AR; de Bock, GH; Gernaat, SAM; Huisman, MG; Izaks, GJ; van der Wal-Huisman, H; van Leeuwen, BL; Weerink, LBM	1
Hogervorst, E; Kassam, S; Kridawati, A; Rahardjo, TB; Shifu, X; Soni, M; Xin, X	1
Field, MS; Stover, PJ	1
Huang, G; Li, Q; Li, W; Liu, H; Ma, F; Song, A; Xu, W; Zhao, J; Zhou, X	1
Choi, BY; Kim, MK; Kim, S; Nam, JH; Oh, DH; Yang, YJ	1
Darvishi-Khezri, H; Enderami, A; Zarghami, M	1
Barbosa, S; Bronauth, L; Cechinel, LR; Confortim, HD; de Oliveira, BC; Deckmann, I; Deniz, BF; Miguel, PM; Pereira, LO; Siqueira, IR	1
Chen, YH; Huang, LL; Liao, JH; Su, C; Xu, X; Yang, YY; Yu, H; Yu, XL; Yuan, L; Yuan, MM; Zhao, M	1
Gaur, R; Kaur, G; Saraswathy, KN; Yadav, S	1
Aniwattanapong, D; Carvalho, AF; Chuchuen, P; Hemrunroj, S; Maes, M; Snabboon, T; Supasitthumrong, T; Tangwongchai, S; Tawankanjanachot, I; Tunvirachaisakul, C	1
McEvoy, CT; McGrattan, AM; McGuinness, B; McKinley, MC; Woodside, JV	1
Abraham, RP; Al-Assaf, AS; Anderson, JL; Chong, LY; Denton, DA; Di Nisio, M; Malik, MA; Martínez, G; McCleery, J; Rutjes, AW; Tabet, N; Vernooij, RW	1
Casey, MC; Cunningham, C; Hoey, L; Hughes, CF; Laird, E; McCarroll, K; McNulty, H; Molloy, AM; Moore, K; O'Kane, M; Strain, JJ; Tracey, F; Ward, M	1
D'Hooge, R; Dekeyster, E; Elens, I; Moons, L	1
Casey, MC; Cunningham, C; Gallagher, AM; Hoey, L; Hughes, CF; Laird, E; McCann, A; McCarroll, K; McNulty, H; Molloy, AM; O'Kane, M; Porter, KM; Strain, S; Tracey, F; Ward, M	1
Cheng, Y; Jiang, H; Li, J; Liu, Q; Liu, Y; Qiu, Z; Shen, Y; Xi, S; Xiao, C; Xie, Z; Xue, Z; Yan, J; Zhang, L	1
Brouwer-Brolsma, EM; Naninck, EFG; Stijger, PC	1
Feng, L; Jiang, YW; Koh, WP; Pan, A; Pan, XF; Sheng, LT; Yuan, JM	1
Baroni, L; Bazzerla, G; Bertola, C; Bonetto, C; Caberlotto, L; Rizzo, G	1
Chang, B; Chen, H; Gao, Y; Huang, G; Shan, C; Tian, L; Zhang, M; Zheng, M	1
An, P; Du, Y; Huang, G; Li, Q; Ma, F; Song, A; Xu, W; Zhao, J; Zhou, X	1
An, P; Du, Y; Huang, G; Song, A; Wang, Q; Zhao, J; Zhou, X	1
Castagna, A; Cotroneo, AM; Fantò, F; Gareri, P; Lacava, R; Malara, A; Monteleone, F; Putignano, S; Rocca, F	1
Ames, D; Bush, AI; Ellis, KA; Faux, NG; Fowler, CJ; Martins, RN; Masters, CL; Pertile, KK; Rembach, A; Rumble, RL; Trounson, B; Wiley, J	1
de Waal, H; Kamphuis, PJ; Lansbergen, MM; Maestú, F; Scheltens, P; Stam, CJ; van Straaten, EC; Wieggers, RL	1
Cheng, D; Huang, C; Jiang, Y; Kong, H; Lu, H; Pang, W; Yang, H	1
Das, SK; Dhar, P; Hota, KB; Hota, SK; Kumar, A; Mahapatra, BB; Norboo, T; Sharma, VK; Srivastava, RB; Vashishtha, V	1
Agnew-Blais, JC; Coker, LH; Hogan, PE; Kang, JH; Smoller, JW; Snetselaar, LG; Wassertheil-Smoller, S	1
Cooper, C; Livingston, G; Lyketsos, CG; Sommerlad, A	1
Araújo, JM; Araújo, JR; Borges, N; Keating, E; Martel, F	1
Han, F; Huang, G; Liu, H; Ma, F; Marseglia, A; Wu, T; Zhao, J	1
Fuchs, D; Greilberger, J; Greilberger, M; Leblhuber, F; Rommer, PS; Schroth, R; Tafeit, E	1
Kim, SY; Lee, HK; Sok, SR	1
Bohlken, J; Flöel, A; Grittner, U; Hahn, A; Köbe, T; Pantel, J; Rujescu, D; Schnelle, A; Schuchardt, JP; Tesky, VA; Witte, AV	1
Refsum, H; Smith, AD	1
Huang, G; Liu, H; Ma, F; Song, A; Wu, T; Xu, W; Zhao, J	1
de Groot, RH; Durga, J; Jolles, J; Kok, FJ; Schiepers, OJ; van Boxtel, MP; Verhoef, P	1
Ames, D; Bush, AI; Ellis, KA; Faux, NG; Fowler, CJ; Laws, SM; Martins, RN; Masters, CL; Pertile, KK; Porter, L; Rembach, A; Rowe, CC; Rumble, RL; Szoeke, C; Taddei, K; Taddei, T; Trounson, BO; Villemagne, VL; Ward, V	1
Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G	1
Gustafson, L; Hultberg, B; Nilsson, K	1
Blasko, I; Fischer, P; Heinz Tragl, K; Hinterberger, M; Jungwirth, S; Kemmler, G; Krampla, W; Leitha, T	1

Reviews

19 review(s) available for folic acid and Cognitive Decline

Article	Year
Effects of Supplementation with Folic Acid and Its Combinations with Other Nutrients on Cognitive Impairment and Alzheimer's Disease: A Narrative Review. Nutrients, 2021, Aug-26, Volume: 13, Issue:9 Topics: Alzheimer Disease; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Humans; Vitamin B Complex	2021
Homocysteine levels, genetic background, and cognitive impairment in Parkinson's disease. Journal of neurology, 2023, Volume: 270, Issue:1 Topics: Case-Control Studies; Cognitive Dysfunction; Folic Acid; Genetic Background; Genotype; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Parkinson Disease; Vitamin B 12	2023
Sustaining an ageing population: the role of micronutrients in frailty and cognitive impairment. The Proceedings of the Nutrition Society, 2023, Volume: 82, Issue:3 Topics: Aged; Aging; Carotenoids; Cognitive Dysfunction; Folic Acid; Frailty; Humans; Longitudinal Studies; Micronutrients; Vitamins	2023
Micro- and Macronutrient Intake and Food Group Frequency Consumed by Subjects with Cognitive Impairment and Dementia in Latin America: A Systematic Review. Journal of Alzheimer's disease : JAD, 2023, Volume: 94, Issue:2 Topics: Ascorbic Acid; Calcium; Cognitive Dysfunction; Dementia; Eating; Energy Intake; Folic Acid; Humans; Iron; Latin America; Vitamin B 12; Vitamins	2023
Features of Plasma Homocysteine, Vitamin B12, and Folate in Parkinson's Disease: An Updated Meta-Analysis. Journal of integrative neuroscience, 2023, Aug-14, Volume: 22, Issue:5 Topics: Cognitive Dysfunction; Folic Acid; Homocysteine; Humans; Parkinson Disease; Vitamin B 12	2023
Assessment of the Dose-Response Relationship Between Folate Exposure and Cognitive Impairment: Synthesizing Data from Documented Studies. Risk analysis : an official publication of the Society for Risk Analysis, 2020, Volume: 40, Issue:2 Topics: Aged; Cognitive Dysfunction; Dose-Response Relationship, Drug; Folic Acid; Humans; Middle Aged; Models, Statistical; Odds Ratio; Risk; Vitamin B 12 Deficiency	2020
Dietary interventions in mild cognitive impairment and dementia. Dialogues in clinical neuroscience, 2019, Volume: 21, Issue:1 Topics: Cognitive Dysfunction; Dementia; Diet; Fatty Acids, Omega-3; Folic Acid; Humans; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome; Vitamin E	2019
Vitamin B-Can it prevent cognitive decline? A systematic review and meta-analysis. Systematic reviews, 2020, 05-15, Volume: 9, Issue:1 Topics: Cognitive Dysfunction; Dietary Supplements; Folic Acid; Humans; Vitamin B 12; Vitamin B Complex	2020
Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis. Journal of Alzheimer's disease : JAD, 2020, Volume: 77, Issue:2 Topics: Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Folic Acid; Humans; Independent Living; Observational Studies as Topic; Vitamin B 12; Vitamin B 6	2020
B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis. Nutrition reviews, 2022, 03-10, Volume: 80, Issue:4 Topics: Aged; Cognition; Cognitive Dysfunction; Dementia; Dietary Supplements; Folic Acid; Humans; Middle Aged; Vitamin B 12; Vitamin B Complex	2022
Nutrition research in cognitive impairment/dementia, with a focus on soya and folate. The Proceedings of the Nutrition Society, 2017, Volume: 76, Issue:4 Topics: Cognitive Dysfunction; Dementia; Female; Folic Acid; Folic Acid Deficiency; Glycine max; Humans; Male; Phytoestrogens; Plant Proteins, Dietary; Soy Foods	2017
Safety of folic acid. Annals of the New York Academy of Sciences, 2018, Volume: 1414, Issue:1 Topics: Animals; Cognitive Dysfunction; Diabetes Mellitus; Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Hypersensitivity; Infant, Newborn; Male; Maximum Tolerated Dose; Neoplasms; Neural Tube Defects; No-Observed-Adverse-Effect Level; Pregnancy; Risk Factors; Safety; Thyroid Diseases; United States; United States Food and Drug Administration	2018
The effects and potential mechanisms of folic acid on cognitive function: a comprehensive review. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2018, Volume: 39, Issue:10 Topics: Animals; Cognition; Cognitive Dysfunction; Dementia; Dietary Supplements; Folic Acid; Humans; Nootropic Agents	2018
Effect of dietary interventions in mild cognitive impairment: a systematic review. The British journal of nutrition, 2018, Volume: 120, Issue:12 Topics: Alzheimer Disease; Attention; Biomarkers; Cognition; Cognitive Dysfunction; Dementia; Diet; Dietary Supplements; Disease Progression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Executive Function; Folic Acid; Ginkgo biloba; Humans; Language; Neuropsychological Tests; Phospholipids; Randomized Controlled Trials as Topic; Vitamin E	2018
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life. The Cochrane database of systematic reviews, 2018, 12-17, Volume: 12 Topics: Adult; Aged; Antioxidants; Ascorbic Acid; beta Carotene; Calcium; Cholecalciferol; Cognition; Cognitive Dysfunction; Copper; Dementia; Dietary Supplements; Folic Acid; Humans; Middle Aged; Minerals; Randomized Controlled Trials as Topic; Selenium; Vitamin A; Vitamin B 12; Vitamin B 6; Vitamin E; Vitamins; Zinc	2018
The Importance of Maternal Folate Status for Brain Development and Function of Offspring. Advances in nutrition (Bethesda, Md.), 2019, 05-01, Volume: 10, Issue:3 Topics: Adult; Brain; Child; Child, Preschool; Cognition; Cognitive Dysfunction; Female; Folic Acid; Humans; Maternal Exposure; Nutritional Status; Pregnancy; Prenatal Exposure Delayed Effects	2019
Modifiable predictors of dementia in mild cognitive impairment: a systematic review and meta-analysis. The American journal of psychiatry, 2015, Volume: 172, Issue:4 Topics: Alzheimer Disease; Cognitive Dysfunction; Dementia; Depression; Diabetes Mellitus; Diet, Mediterranean; Disease Progression; Educational Status; Folic Acid; Humans; Longitudinal Studies; Metabolic Syndrome; Prediabetic State; Protective Factors; Risk Factors	2015
Folates and aging: Role in mild cognitive impairment, dementia and depression. Ageing research reviews, 2015, Volume: 22 Topics: Aged; Aging; Brain; Cognition; Cognitive Dysfunction; Dementia; Depression; Disease Progression; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Vitamin B Complex	2015
Homocysteine, B Vitamins, and Cognitive Impairment. Annual review of nutrition, 2016, 07-17, Volume: 36 Topics: Aging; Animals; Biomarkers; Cerebrovascular Circulation; Cognition Disorders; Cognitive Dysfunction; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neurodegenerative Diseases; Nootropic Agents; Nutritional Status; Practice Guidelines as Topic; Risk Factors; Vitamin B 12; Vitamin B 6	2016

Trials

17 trial(s) available for folic acid and Cognitive Decline

Article	Year
Protocol for thiamine and folic acid in the treatment of cognitive impairment in maintenance haemodialysis patients: a prospective, randomised, placebo-controlled, double-blind, multicentre study. BMJ open, 2021, 12-14, Volume: 11, Issue:12 Topics: China; Cognitive Dysfunction; Double-Blind Method; Folic Acid; Humans; Multicenter Studies as Topic; Pilot Projects; Prospective Studies; Randomized Controlled Trials as Topic; Renal Dialysis; Thiamine	2021
B Vitamin Supplementation Slows Cognitive Decline in Mild Cognitive Impairment Patients with Frontal Lobe Atrophy. Journal of Alzheimer's disease : JAD, 2022, Volume: 89, Issue:4 Topics: Aspirin; Atrophy; Cognition; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Frontal Lobe; Homocysteine; Humans; Vitamin B 12; Vitamin B Complex	2022
Dietary intakes and biomarker patterns of folate, vitamin B Clinical epigenetics, 2019, 10-11, Volume: 11, Issue:1 Topics: Aged; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Pyrophosphatases; Thioredoxin Reductase 1; Vitamin B 12; Vitamin B 6	2019
A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients. Clinical nutrition (Edinburgh, Scotland), 2020, Volume: 39, Issue:8 Topics: Aged; Aged, 80 and over; Cognition; Cognitive Dysfunction; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Treatment Outcome; Vitamin B 12; Vitamin B Complex	2020
Effect of folic acid combined with docosahexaenoic acid intervention on mild cognitive impairment in elderly: a randomized double-blind, placebo-controlled trial. European journal of nutrition, 2021, Volume: 60, Issue:4 Topics: Adult; Aged; China; Cognitive Dysfunction; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Folic Acid; Humans	2021
Effects of Folic Acid Combined with DHA Supplementation on Cognitive Function and Amyloid-β-Related Biomarkers in Older Adults with Mild Cognitive Impairment by a Randomized, Double Blind, Placebo-Controlled Trial. Journal of Alzheimer's disease : JAD, 2021, Volume: 81, Issue:1 Topics: Aged; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Cognition; Cognitive Dysfunction; Docosahexaenoic Acids; Double-Blind Method; Female; Folic Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Peptide Fragments	2021
Paraoxonase 1, B Vitamins Supplementation, and Mild Cognitive Impairment. Journal of Alzheimer's disease : JAD, 2021, Volume: 81, Issue:3 Topics: Aryldialkylphosphatase; Brain; Cognition; Cognitive Dysfunction; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Magnetic Resonance Imaging; Male; Mass Spectrometry; Neuropsychological Tests; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2021
B vitamins and cognition in subjects with small vessel disease: A Substudy of VITATOPS, a randomized, placebo-controlled trial. Journal of the neurological sciences, 2017, 08-15, Volume: 379 Topics: Aged; Cognitive Dysfunction; Double-Blind Method; Female; Folic Acid; Homocystine; Humans; Male; Middle Aged; Neuropsychological Tests; Stroke; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2017
Effects of folic acid supplementation on cognitive function and Aβ-related biomarkers in mild cognitive impairment: a randomized controlled trial. European journal of nutrition, 2019, Volume: 58, Issue:1 Topics: Aged; Amyloidogenic Proteins; Biomarkers; Cluster Analysis; Cognition; Cognitive Dysfunction; Dietary Supplements; DNA Methylation; Female; Folic Acid; Follow-Up Studies; Humans; Male	2019
Effects of Folic Acid and Vitamin B12, Alone and in Combination on Cognitive Function and Inflammatory Factors in the Elderly with Mild Cognitive Impairment: A Single-blind Experimental Design. Current Alzheimer research, 2019, Volume: 16, Issue:7 Topics: Aged; Cognition; Cognitive Dysfunction; Cytokines; Female; Folic Acid; Humans; Male; Single-Blind Method; Vitamin B 12; Vitamin B Complex	2019
Effectiveness and safety of citicoline in mild vascular cognitive impairment: the IDEALE study. Clinical interventions in aging, 2013, Volume: 8 Topics: Activities of Daily Living; Administration, Oral; Aged; Aged, 80 and over; Cognitive Dysfunction; Cytidine Diphosphate Choline; Depression; Female; Folic Acid; Geriatric Assessment; Humans; Magnetic Resonance Imaging; Male; Mental Disorders; Nootropic Agents; Thyroid Hormones; Tomography, X-Ray Computed; Vascular Diseases; Vitamin B 12	2013
The effect of souvenaid on functional brain network organisation in patients with mild Alzheimer's disease: a randomised controlled study. PloS one, 2014, Volume: 9, Issue:1 Topics: Aged; Alzheimer Disease; Brain; Choline; Cognitive Dysfunction; Docosahexaenoic Acids; Eicosapentaenoic Acid; Electroencephalography; Folic Acid; Food, Formulated; Humans; Likelihood Functions; Middle Aged; Nerve Net; Phospholipids; Regression Analysis; Selenium; Synapses; Treatment Outcome; Uridine Monophosphate; Vitamins	2014
B vitamin supplementation improves cognitive function in the middle aged and elderly with hyperhomocysteinemia. Nutritional neuroscience, 2016, Volume: 19, Issue:10 Topics: Aged; Aged, 80 and over; Aging; China; Cognitive Dysfunction; Dietary Supplements; Elder Nutritional Physiological Phenomena; Female; Folic Acid; Follow-Up Studies; Homes for the Aged; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Nursing Homes; Prevalence; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12; Vitamin B 6	2016
Effects of 6-Month Folic Acid Supplementation on Cognitive Function and Blood Biomarkers in Mild Cognitive Impairment: A Randomized Controlled Trial in China. The journals of gerontology. Series A, Biological sciences and medical sciences, 2016, Volume: 71, Issue:10 Topics: Aged; Biomarkers; China; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Treatment Outcome; Vitamin B 12	2016
Lowered Levels of Carbonyl Proteins after Vitamin B Supplementation in Patients with Mild Cognitive Impairment and Alzheimer's Disease. Neuro-degenerative diseases, 2016, Volume: 16, Issue:3-4 Topics: Age Factors; Aged; Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Dietary Supplements; Discriminant Analysis; Female; Folic Acid; Humans; Kynurenine; Male; Mental Status Schedule; Middle Aged; ROC Curve; Thiamine; Treatment Outcome; Tryptophan; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2016
Vitamin B-12 concentration, memory performance, and hippocampal structure in patients with mild cognitive impairment. The American journal of clinical nutrition, 2016, Volume: 103, Issue:4 Topics: Aged; Aged, 80 and over; Apolipoprotein E4; Cognition; Cognitive Dysfunction; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Genotyping Techniques; Hippocampus; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Memory; Middle Aged; Polymorphism, Single Nucleotide; Verbal Learning; Vitamin B 12	2016
DNA methylation and cognitive functioning in healthy older adults. The British journal of nutrition, 2012, Volume: 107, Issue:5 Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Aged; Aging; Cognitive Dysfunction; Cross-Sectional Studies; Cytosine; DNA Methylation; Double-Blind Method; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Genetic Association Studies; Homocysteine; Humans; Leukocytes; Male; Middle Aged; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales	2012

Other Studies

61 other study(ies) available for folic acid and Cognitive Decline

Article	Year
B Vitamins Prevent Iron-Associated Brain Atrophy and Domain-Specific Effects of Iron, Copper, Aluminum, and Silicon on Cognition in Mild Cognitive Impairment. Journal of Alzheimer's disease : JAD, 2021, Volume: 84, Issue:3 Topics: Aged; Aluminum; Atrophy; Brain; Cognitive Dysfunction; Copper; Female; Folic Acid; Humans; Iron; Male; Mass Spectrometry; Neuropsychological Tests; Silicon; Vitamin B 12; Vitamin B 6	2021
B Vitamins Supplementation Can Improve Cognitive Functions and May Relate to the Enhancement of Transketolase Activity in A Rat Model of Cognitive Impairment Associated with High-fat Diets. Current medical science, 2021, Volume: 41, Issue:5 Topics: Animals; Cognitive Dysfunction; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Folic Acid; Gene Expression Regulation, Enzymologic; Male; Morris Water Maze Test; Niacin; Pyridoxine; Rats; Riboflavin; Thiamine; Transketolase; Vitamin B 12; Vitamin B Complex	2021
Low folate predicts accelerated cognitive decline: 8-year follow-up of 3140 older adults in Ireland. European journal of clinical nutrition, 2022, Volume: 76, Issue:7 Topics: Aged; Cognition; Cognitive Dysfunction; Folic Acid; Follow-Up Studies; Humans; Ireland; Longitudinal Studies	2022
Plasma folate levels in relation to cognitive impairment: a community-based cohort of older adults in China. European journal of nutrition, 2022, Volume: 61, Issue:5 Topics: Aged; China; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Middle Aged; Vitamin B 12	2022
Evaluation of the Effects of Folic Acid Combined with Atorvastatin on the Poststroke Cognitive Impairment by Low-Rank Matrix Denoising Algorithm-Based MRI Imaging. Contrast media & molecular imaging, 2022, Volume: 2022 Topics: Algorithms; Atorvastatin; Cognitive Dysfunction; Folic Acid; Humans; Ischemic Stroke; Magnetic Resonance Imaging; Stroke	2022
Vitamin B12 deficiency. Vitamins and hormones, 2022, Volume: 119 Topics: Aged; Biological Transport; Cognitive Dysfunction; Folic Acid; Humans; Vitamin B 12; Vitamin B 12 Deficiency	2022
Influences of Vitamin B Nutrients, 2022, Apr-02, Volume: 14, Issue:7 Topics: Aged; Aged, 80 and over; Atrophy; Cognition; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Homocysteine; Humans; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins	2022
Multimodal strategy to rescue the brain in mild cognitive impairment: Ketogenic oral nutrition supplementation with B vitamins and aerobic exercise. European journal of clinical investigation, 2022, Volume: 52, Issue:9 Topics: Brain; Cognition; Cognitive Dysfunction; Dietary Supplements; Exercise; Folic Acid; Humans; Vitamin B 12; Vitamin B Complex	2022
Circulating folate concentrations and the risk of mild cognitive impairment: A prospective study on the older Chinese population without folic acid fortification. European journal of neurology, 2022, Volume: 29, Issue:10 Topics: Aged; Apolipoprotein E4; China; Cognitive Dysfunction; Cohort Studies; Folic Acid; Homocysteine; Humans; Prospective Studies; Vitamin B 12	2022
A Retrospective Study on Clinical Assessment of Cognitive Impairment in a Swedish Cohort: Is There Inequality Between Natives and Foreign-Born? Journal of Alzheimer's disease : JAD, 2022, Volume: 89, Issue:4 Topics: Albumins; Alzheimer Disease; Atrophy; Biomarkers; Calcium; Cognitive Dysfunction; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Retrospective Studies; Sweden; Thyrotropin; Vitamin B 12	2022
One-Carbon Metabolism Biomarkers and Risks of Incident Neurocognitive Disorder among Cognitively Normal Older Adults. Nutrients, 2022, Aug-27, Volume: 14, Issue:17 Topics: Aged; Biomarkers; Carbon; Cognitive Dysfunction; Dementia; Folic Acid; Homocysteine; Humans; Vitamin B 12	2022
Serum Homocysteine, Vitamin B12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia. Journal of Alzheimer's disease : JAD, 2022, Volume: 90, Issue:2 Topics: Alzheimer Disease; Cognitive Dysfunction; Dementia, Vascular; Folic Acid; Frontotemporal Dementia; Homocysteine; Humans; Hyperhomocysteinemia; Vitamin B 12	2022
Cognitive Decline Related to Diet Pattern and Nutritional Adequacy in Alzheimer's Disease Using Surface-Based Morphometry. Nutrients, 2022, Dec-13, Volume: 14, Issue:24 Topics: Alzheimer Disease; Atrophy; Coffee; Cognitive Dysfunction; Diet; Folic Acid; Humans; Lipids; Magnetic Resonance Imaging; Tea	2022
Association between dietary folate intake and cognitive impairment in older US adults: National Health and Nutrition Examination Survey. Archives of gerontology and geriatrics, 2023, Volume: 109 Topics: Adult; Aged; Cognitive Dysfunction; Cross-Sectional Studies; Diet; Eating; Folic Acid; Humans; Middle Aged; Nutrition Surveys	2023
Study of Diet Habits and Cognitive Function in the Chinese Middle-Aged and Elderly Population: The Association between Folic Acid, B Vitamins, Vitamin D, Coenzyme Q10 Supplementation and Cognitive Ability. Nutrients, 2023, Mar-01, Volume: 15, Issue:5 Topics: Aged; Alzheimer Disease; China; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Dietary Supplements; East Asian People; Feeding Behavior; Folic Acid; Humans; Middle Aged; Vitamin A; Vitamin B 12; Vitamin B Complex; Vitamin D	2023
Long-term dietary folic acid supplementation attenuated aging-induced hippocampus atrophy and promoted glucose uptake in 25-month-old rats with cognitive decline. The Journal of nutritional biochemistry, 2023, Volume: 117 Topics: Aging; Animals; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Glucose; Hippocampus; Male; Rats; Rats, Sprague-Dawley	2023
Association of Leukocyte Telomere Length with Mild Cognitive Impairment and Alzheimer's Disease: Role of Folate and Homocysteine. Dementia and geriatric cognitive disorders, 2019, Volume: 48, Issue:1-2 Topics: Aged; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Correlation of Data; Female; Folic Acid; Homocysteine; Humans; Leukocytes; Male; Middle Aged; Telomere Shortening	2019
Folic acid delays age-related cognitive decline in senescence-accelerated mouse prone 8: alleviating telomere attrition as a potential mechanism. Aging, 2019, 11-22, Volume: 11, Issue:22 Topics: Aging; Animals; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Mice; Nerve Degeneration; Telomere Shortening	2019
The relationship between cognitive impairment and homocysteine in a B12 and folate deficient population in China: A cross-sectional study. Medicine, 2019, Volume: 98, Issue:47 Topics: Aged; Aged, 80 and over; Alzheimer Disease; China; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12; Vitamin B 12 Deficiency	2019
Nutrition and aging: is there a link to cognitive health? International journal of food sciences and nutrition, 2020, Volume: 71, Issue:3 Topics: Aged; Aging; Cognition; Cognitive Dysfunction; Diet; Feeding Behavior; Folic Acid; Humans; Nutritional Status	2020
The Stimulation of Neurogenesis Improves the Cognitive Status of Aging Rats Subjected to Gestational and Perinatal Deficiency of B9-12 Vitamins. International journal of molecular sciences, 2020, Oct-28, Volume: 21, Issue:21 Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Cognitive Dysfunction; Female; Folic Acid; Male; Maze Learning; Neurogenesis; Pregnancy; Rats; Rats, Wistar; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins	2020
The effect of folate and VitB Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 81 Topics: Aged; Cognition; Cognitive Dysfunction; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Treatment Outcome; Vitamin B 12	2020
Serum folate levels and cognitive performance in the ELSA-Brasil baseline assessment. Arquivos de neuro-psiquiatria, 2020, Volume: 78, Issue:11 Topics: Adult; Aged; Brazil; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Folic Acid; Humans; Longitudinal Studies; Middle Aged	2020
Hyperhomocysteinemia and Dementia Associated With Severe Cortical Atrophy, but No Amyloid Burden. Journal of geriatric psychiatry and neurology, 2022, Volume: 35, Issue:1 Topics: Aged; Alzheimer Disease; Atrophy; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia	2022
Association between methionine cycle metabolite-related diets and mild cognitive impairment in older Chinese adults: a population-based observational study. Nutritional neuroscience, 2022, Volume: 25, Issue:7 Topics: Aged; China; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Diet; Folic Acid; Humans; Methionine; Middle Aged; Risk Factors	2022
Plasma phosphatidylcholines and vitamin B12/folate levels are possible prognostic biomarkers for progression of Alzheimer's disease. Experimental gerontology, 2021, Volume: 147 Topics: Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Disease Progression; Folic Acid; Humans; Phosphatidylcholines; Prognosis; Vitamin B 12; Vitamins	2021
LncRNA-mRNA Expression Profiles and Functional Networks Associated with Cognitive Impairment in Folate-deficient Mice. Combinatorial chemistry & high throughput screening, 2022, Volume: 25, Issue:5 Topics: Animals; Cognitive Dysfunction; Folic Acid; Gene Regulatory Networks; Mice; MicroRNAs; RNA, Long Noncoding; RNA, Messenger	2022
Interactions Between Handgrip Strength and Serum Folate and Homocysteine Levels on Cognitive Function in the Elderly Chinese Population. Journal of Alzheimer's disease : JAD, 2021, Volume: 80, Issue:4 Topics: Aged; Aged, 80 and over; China; Cognition; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Female; Folic Acid; Hand Strength; Homocysteine; Humans; Linear Models; Male; Mental Status and Dementia Tests; Middle Aged	2021
[Cobalamin in the complex treatment and prevention of cognitive impairment]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2021, Volume: 121, Issue:3 Topics: Aged; Biomarkers; Cognitive Dysfunction; Female; Folic Acid; Humans; Methylmalonic Acid; Vitamin B 12; Vitamin B 12 Deficiency	2021
Folic acid alleviates the blood brain barrier permeability and oxidative stress and prevents cognitive decline in sepsis-surviving rats. Microvascular research, 2021, Volume: 137 Topics: Animals; Antioxidants; Behavior, Animal; Blood-Brain Barrier; Capillary Permeability; Cognition; Cognitive Dysfunction; Disease Models, Animal; Folic Acid; Lipid Peroxidation; Male; Memory; Oxidative Stress; Protein Carbonylation; Rats, Wistar; Sepsis	2021
Folic acid alleviates age-related cognitive decline and inhibits apoptosis of neurocytes in senescence-accelerated mouse prone 8: deoxythymidine triphosphate biosynthesis as a potential mechanism. The Journal of nutritional biochemistry, 2021, Volume: 97 Topics: Aging; Animals; Apoptosis; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Memory; Mice; Morris Water Maze Test; Neurons; Quinazolines; Telomere Shortening; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Uracil	2021
A prospective evaluation of the depression-nutrient intake reverse causality hypothesis in a cohort of community-dwelling older Canadians. The British journal of nutrition, 2017, Volume: 117, Issue:7 Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognitive Dysfunction; Cohort Studies; Depression; Diet, Healthy; Elder Nutritional Physiological Phenomena; Female; Folic Acid; Geriatric Assessment; Humans; Incidence; Longitudinal Studies; Male; Nutrition Assessment; Patient Compliance; Prospective Studies; Psychiatric Status Rating Scales; Quebec; Risk; Vitamin B 12; Vitamin B 6	2017
Can Nutrition or Inflammation Moderate the Age-Cognition Association Among Older Adults? The journals of gerontology. Series B, Psychological sciences and social sciences, 2019, 01-10, Volume: 74, Issue:2 Topics: Age Factors; Aged; beta Carotene; Biomarkers; C-Reactive Protein; Cognition; Cognitive Dysfunction; Diet; Female; Ferritins; Fibrinogen; Folic Acid; Homocysteine; Humans; Inflammation; Iron; Male; Middle Aged; Neuropsychological Tests; Nutrition Surveys; Nutritional Status; Vitamins	2019
Diagnostic Values of Serum Levels of Homocysteine and Uric Acid for Predicting Vascular Mild Cognitive Impairment in Patients with Cerebral Small Vessel Disease. Medical science monitor : international medical journal of experimental and clinical research, 2017, May-10, Volume: 23 Topics: Aged; Case-Control Studies; Cerebral Small Vessel Diseases; Cholesterol; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; ROC Curve; Uric Acid; Vitamin B 12	2017
Toxoplasma Gondii Moderates the Association between Multiple Folate-Cycle Factors and Cognitive Function in U.S. Adults. Nutrients, 2017, Jun-02, Volume: 9, Issue:6 Topics: Adult; Biomarkers; Cognition; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutrition Surveys; Sample Size; Socioeconomic Factors; Toxoplasma; Toxoplasmosis; Vitamin B 12; Young Adult	2017
One-Carbon Metabolism Biomarkers and Cognitive Decline in the Very Old: The Newcastle 85+ Study. Journal of the American Medical Directors Association, 2017, Sep-01, Volume: 18, Issue:9 Topics: Aged, 80 and over; Biomarkers; Cognitive Dysfunction; England; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Male; Prospective Studies; Vitamin B 12	2017
Plasma Homocysteine and Serum Folate and Vitamin B Nutrients, 2017, Jul-08, Volume: 9, Issue:7 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Odds Ratio; Psychiatric Status Rating Scales; Risk Factors; Vitamin B 12	2017
Vitamin Status and the Development of Postoperative Cognitive Decline in Elderly Surgical Oncologic Patients. Annals of surgical oncology, 2018, Volume: 25, Issue:1 Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Preoperative Period; Vitamin B 12	2018
Cognitive impairment is associated with elevated serum homocysteine levels among older adults. European journal of nutrition, 2019, Volume: 58, Issue:1 Topics: Aged; Causality; Cognitive Dysfunction; Cohort Studies; Comorbidity; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Prevalence; Republic of Korea; Vitamin B 12	2019
Folic acid supplementation during pregnancy prevents cognitive impairments and BDNF imbalance in the hippocampus of the offspring after neonatal hypoxia-ischemia. The Journal of nutritional biochemistry, 2018, Volume: 60 Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Dietary Supplements; Female; Folic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Maternal-Fetal Exchange; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar	2018
Chronic folate deficiency induces glucose and lipid metabolism disorders and subsequent cognitive dysfunction in mice. PloS one, 2018, Volume: 13, Issue:8 Topics: Animals; Cognition; Cognitive Dysfunction; Diet; Female; Folic Acid; Folic Acid Deficiency; Glucose; Homocysteine; Insulin Resistance; Lipid Metabolism; Mice; Mice, Inbred ICR; Time Factors	2018
Association of vitamin B12 mediated hyperhomocysteinemia and methylenetetrafolate reductase (C677T) gene polymorphism with cognitive impairment: A population based study from North India. Psychiatry research, 2018, Volume: 270 Topics: Adult; Aged; Cognitive Dysfunction; Comorbidity; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; India; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Vitamin B 12	2018
Validation of the Thai version of the short Boston Naming Test (T-BNT) in patients with Alzheimer's dementia and mild cognitive impairment: clinical and biomarker correlates. Aging & mental health, 2019, Volume: 23, Issue:7 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoprotein E4; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Humans; Language Tests; Male; Memory, Episodic; Reproducibility of Results; Thailand	2019
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study. Journal of the American Medical Directors Association, 2019, Volume: 20, Issue:5 Topics: Aged; Aging; Biomarkers; Cognitive Dysfunction; Cohort Studies; Cross-Sectional Studies; Depression; Female; Folic Acid; Homocysteine; Humans; Ireland; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Pyridoxine; Vitamin B 12; Vitamin B Complex	2019
Methotrexate Affects Cerebrospinal Fluid Folate and Tau Levels and Induces Late Cognitive Deficits in Mice. Neuroscience, 2019, 04-15, Volume: 404 Topics: Animals; Animals, Newborn; Antimetabolites, Antineoplastic; Cognitive Dysfunction; Female; Folic Acid; Hippocampus; Injections, Spinal; Maze Learning; Methotrexate; Mice; Mice, Inbred C57BL; Random Allocation; tau Proteins	2019
Hyperglycemia and Metformin Use Are Associated With B Vitamin Deficiency and Cognitive Dysfunction in Older Adults. The Journal of clinical endocrinology and metabolism, 2019, 10-01, Volume: 104, Issue:10 Topics: Aged; Aged, 80 and over; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Geriatric Assessment; Humans; Hyperglycemia; Independent Living; Male; Metformin; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6	2019
Disrupted folate metabolism with anesthesia leads to myelination deficits mediated by epigenetic regulation of ERMN. EBioMedicine, 2019, Volume: 43 Topics: Anesthesia; Animals; Biomarkers; Cognitive Dysfunction; Computational Biology; Demyelinating Diseases; Disease Models, Animal; Epigenesis, Genetic; Female; Folic Acid; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Genome; Genomics; Macaca mulatta; Male; Maze Learning; Mice; Myelin Sheath; Signal Transduction; Thymidylate Synthase	2019
Association Between Dietary Intakes of B Vitamins in Midlife and Cognitive Impairment in Late-Life: The Singapore Chinese Health Study. The journals of gerontology. Series A, Biological sciences and medical sciences, 2020, 05-22, Volume: 75, Issue:6 Topics: Aged; Cognitive Dysfunction; Diet Surveys; Dose-Response Relationship, Drug; Eating; Female; Folic Acid; Humans; Interviews as Topic; Logistic Models; Male; Mental Status and Dementia Tests; Middle Aged; Niacin; Prospective Studies; Riboflavin; Singapore; Surveys and Questionnaires; Thiamine; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2020
Association Between Cognitive Impairment and Vitamin B12, Folate, and Homocysteine Status in Elderly Adults: A Retrospective Study. Journal of Alzheimer's disease : JAD, 2019, Volume: 70, Issue:2 Topics: Aged; Aged, 80 and over; Biomarkers; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency	2019
Relationship between inflammatory markers and mild cognitive impairment in Chinese patients with type 2 diabetes: a case-control study. BMC endocrine disorders, 2019, Jul-11, Volume: 19, Issue:1 Topics: Aged; C-Reactive Protein; China; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Folic Acid; Humans; Interleukin-6; Logistic Models; Multivariate Analysis; Odds Ratio; Tumor Necrosis Factor-alpha	2019
Relationship between folate, vitamin B International journal of food sciences and nutrition, 2020, Volume: 71, Issue:3 Topics: Aged; Case-Control Studies; China; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Transaminases; Vitamin B 12	2020
An anemia of Alzheimer's disease. Molecular psychiatry, 2014, Volume: 19, Issue:11 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anemia; Australia; Cognitive Dysfunction; Cross-Sectional Studies; Female; Folic Acid; Hemoglobins; Humans; Iron; Male; Middle Aged; Prospective Studies; Risk Factors; Transferrin	2014
Domain specific changes in cognition at high altitude and its correlation with hyperhomocysteinemia. PloS one, 2014, Volume: 9, Issue:7 Topics: Acclimatization; Adult; Altitude; Cognition; Cognitive Dysfunction; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Neuropsychological Tests; Vitamin B 12	2014
[The vitamins B₆, B₁₂ and folic acid - successful strategy for increasing vitality?]. Forschende Komplementarmedizin (2006), 2014, Volume: 21, Issue:3 Topics: Cognitive Dysfunction; Depression; Folic Acid; Humans; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2014
Folate, vitamin B-6, and vitamin B-12 intake and mild cognitive impairment and probable dementia in the Women's Health Initiative Memory Study. Journal of the Academy of Nutrition and Dietetics, 2015, Volume: 115, Issue:2 Topics: Aged; Cognitive Dysfunction; Dementia; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Longitudinal Studies; Middle Aged; Motor Activity; Proportional Hazards Models; Prospective Studies; Randomized Controlled Trials as Topic; Socioeconomic Factors; Treatment Outcome; Vitamin B 12; Vitamin B 6	2015
Effects of Multivitamin Supplements on Cognitive Function, Serum Homocysteine Level, and Depression of Korean Older Adults With Mild Cognitive Impairment in Care Facilities. Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing, 2016, Volume: 48, Issue:3 Topics: Aged; Cognitive Dysfunction; Depression; Dietary Supplements; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Male; Republic of Korea; Residential Facilities; Treatment Outcome; Vitamin B 12; Vitamin B 6	2016
Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI. Scientific reports, 2016, 11-23, Volume: 6 Topics: Aged; China; Cognition; Cognitive Dysfunction; Cytokines; Dietary Supplements; Female; Folic Acid; Humans; Male; Middle Aged	2016
Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study. Journal of Alzheimer's disease : JAD, 2011, Volume: 27, Issue:4 Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Analysis of Variance; Australia; Brain; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Vitamin B 12	2011
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats. European journal of nutrition, 2013, Volume: 52, Issue:3 Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine	2013
Elevated plasma homocysteine level is not primarily related to Alzheimer's disease. Dementia and geriatric cognitive disorders, 2012, Volume: 34, Issue:2 Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Renal Insufficiency; Risk Factors; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency	2012
Conversion from mild cognitive impairment to dementia: influence of folic acid and vitamin B12 use in the VITA cohort. The journal of nutrition, health & aging, 2012, Volume: 16, Issue:8 Topics: Aged; Aging; Atrophy; Austria; Brain; Cognitive Dysfunction; Cohort Studies; Dementia; Dietary Supplements; Disease Progression; Female; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Longitudinal Studies; Male; Prospective Studies; Retrospective Studies; Vitamin B 12	2012