folic acid has been researched along with Cleft Spine in 229 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (1.75) | 18.7374 |
| 1990's | 48 (20.96) | 18.2507 |
| 2000's | 78 (34.06) | 29.6817 |
| 2010's | 66 (28.82) | 24.3611 |
| 2020's | 33 (14.41) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, A; Wang, L; Zhu, H | 1 |
| Brei, TJ; Farr, SL; Kirby, RS; Leedom, VO; Pabst, LJ; Riley, C; Van Zutphen, AR | 1 |
| Chang, S; Jie, M; Lu, X; Pei, P; Sun, C; Wang, L; Wang, S; Wu, L; Yang, S; Zhang, T | 1 |
| Berry, RJ; Crider, KS; Li, S; Li, Z; Moore, CA; Rose, CE; Yeung, LF; Zhou, Y | 1 |
| Arynchyna-Smith, A; Berry, RJ; Blount, J; Botto, LD; Caceres, A; Fieggen, G; Ghotme, KA; Kancherla, V; Karmarkar, S; Kibruyisfaw, Z; Oakley, GP; Roozen, S; Rosseau, G; Rowe, LA; Shlobin, NA; Zimmerman, K | 1 |
| Heilbrunn, ES; Lekoubou, A; Ssentongo, AE; Ssentongo, P; Ssenyonga, LVN | 1 |
| Adisa, O; Alverson, CJ; Arnold, K; Dean, JH; Denson, L; Ethen, M; Evans, J; Flood, T; Hansen, B; Isenburg, J; Kirby, RS; Mai, CT; Moore, CA; Nance, A; Nestoridi, E; Rice, S; Shan, X; Yue, X; Zielke, K | 1 |
| Aguiar-Pulido, V; Cabrera, RM; Cao, X; Finnell, RH; Han, X; Karki, M; Lei, Y; Lin, YL; Ramirez, PAP; Ross, ME; Shaw, GM; Wlodarczyk, BJ; Yang, W; Zhang, C | 1 |
| Blount, JP; Boop, FA; Caceres, A; Ghotme, KA; Kancherla, V; Lam, S; Ocal, E; Park, KB; Roach, JT; Rosseau, G; Shlobin, NA | 1 |
| Kancherla, V; Oakley, GP; Pachón, H; Priyadarshini, P; Wagh, K | 1 |
| Bradko, V; Castillo, H; Castillo, J; Gandy, K; Kelly, M; MacDonald, B; Queally, J; Thibadeau, J | 1 |
| Brei, T; Castillo, H; Castillo, J; Thibadeau, JK | 1 |
| Kancherla, V; Oakley, G; Singer, TG | 1 |
| Coelho, G; da Costa Benalia, VH; Dos Santos Silva, RP; Estevão, I; Niquen-Jimenez, M; Salomão, F; Varjão Vieira, E; Zanon, N | 1 |
| Blount, JP; Boop, FA; Caceres, A; Ghotme, K; Ocal, E; Pattisapu, JV; Rosseau, G; Shlobin, NA | 1 |
| Dos Santos, AM; Rodrigues, VB; Santos, LMP; Silva, END | 1 |
| Oakley, GP | 7 |
| Ashagre, Y; Biluts, H; Dorsey, A; Kancherla, V; Koning, J; Koning, M; O'Neill, P; Woldermarium, M; Yesehak, B; Zewdie, K | 1 |
| Blount, JP; Caceres, A | 1 |
| Bonilla, IL; Finnell, RH; González, F; Montes Pastora, M; Pastora Bucardo, DM; Pimienta Ramirez, PA; Vielot, NA | 1 |
| Bowman, R; Reynolds, RA; Rosseau, G; Shlobin, NA; Vance, EH | 1 |
| Park, KB; Pattisapu, JV; Rao, BH; Tesfaye, N; Veerappan, VR; Vijayasekhar, MV; White, C | 1 |
| Dixon, M; Kancherla, V; Magana, T; Mulugeta, A; Oakley, GP | 1 |
| Henderson, D; Majige, R; Ndossi, M; Shabani, H; Sued, M | 1 |
| Oakley, G; Smith, MA | 1 |
| Dixon, M; Kancherla, V; Oakley, GP; Tsang, B; Wagh, K | 1 |
| Copp, AJ; D'Souza, SW; Glazier, JD; Greene, NDE | 1 |
| Kancherla, V; Oakley, GP; Pachón, H; Wagh, K | 1 |
| Belete, A; Biluts, H; Kancherla, V; Kibruyisfaw, Z; Koning, J; Koning, M; Woldemariam, M | 1 |
| Du, RY; Lam, S; LoPresti, MA; Shlobin, NA | 1 |
| Kancherla, V; Martinez, H; Oakley, GP; Pachón, H | 1 |
| Blount, JP; Caceres, A; Chatterjee, S; Fieggen, G; Messing-Jünger, M; Salomao, JF | 1 |
| Esposito, DB; Mitchell, AA; Parker, SE; Tinker, SC; Werler, MM | 1 |
| Dai, XL; Jin, MH; Liu, GC; Mi, NN; Ren, XY; Wang, J; Wang, SQ; Zhang, J | 1 |
| Kerr, SM; Mitchell, AA; Parker, SE; Tinker, SC; Werler, MM | 1 |
| Kancherla, V; Oakley, GP | 2 |
| Baldessarini, RJ; Patel, N; Viguera, AC | 1 |
| Kancherla, V | 1 |
| Andrews, JG; Bandlamuri, S; Contreras, D; Eldridge, C; Flood, TJ; Galindo, MK; Rice, S | 1 |
| Turner, MJ | 1 |
| Johnson, Q; Kancherla, V; Oakley, GP; Wagh, K | 1 |
| Kancherla, V; Oakley, GP; Redpath, B | 1 |
| Delany, V; Lynch, C; McDonnell, R; McKeating, A; O'Mahony, MT; Turner, MJ | 1 |
| Asfaw, S; Berhe, Y; Berihu, BA; Gebreselassie, K; Magana, T; Mulugeta, A; Welderufael, AL | 1 |
| Agborsangaya, BC; Bedard, T; Crawford, S; Lowry, RB; MacFarlane, AJ; Sibbald, B | 1 |
| Averbach, H; Kancherla, V; Oakley, GP | 1 |
| AlOjan, A; AlShammari, M; Ammar, A; Othman, SA | 1 |
| Mitchell, AA; Parker, SE; Tinker, SC; Werler, MM; Yazdy, MM | 1 |
| Benedum, CM; Mitchell, AA; Werler, MM; Yazdy, MM | 1 |
| Iwagaki, S; Kihira, M; Kondo, A; Nakanishi, Y; Okai, I; Shimosuka, Y; Shinozaki, K | 1 |
| Bell, KN; Johnson, Q; Kancherla, V; Oakley, GP; Williamson, R; Youngblood, ME | 1 |
| Fujimaki, H; Ihara, S; Inoue, K; Kondo, A; Matsuo, K; Morota, N; Saisu, T; Shimokawa, S; Shimosuka, Y; Watanabe, T | 1 |
| Cifuentes O, L; Nazer H, J | 1 |
| Devine, O; Dowling, NF; Gilboa, SM; Hamner, HC; Honein, MA; Mai, C; Reefhuis, J; Tinker, SC | 1 |
| Alfaro-Calvo, T; Azofeifa, A; Barboza-Argüello, Mde L; Flores, AL; Mulinare, J; Rodríguez-Aguilar, S; Umaña-Solís, LM; Valencia, D | 1 |
| Chen, Q; Finnell, RH; Gray, JD; Gross, SS; Hansler, A; Ross, ME | 1 |
| Agam, G; Al-Gazali, L; Balasubramanian, S; Börnigen, D; Cem, M; Dave, P; Dubchak, I; Gilliam, TC; Ma, J; Maltsev, N; Mason, CE; Meyden, C; Mirzaa, GM; Paciorkowski, AR; Poliakov, A; Ross, ME; Sulakhe, D; Taylor, A; Wang, S; Xie, B; Xu, J | 1 |
| Ethen, M; Flood, TJ; Frohnert, B; Isenburg, J; Kirby, RS; Mai, CT; Mulinare, J; Williams, J | 1 |
| Date, H; Kondo, A; Miyazato, M; Morishima, T; Morota, N; Pooh, KH; Sakai, H; Shirane, R; Watanabe, T; Yoshifuji, K | 1 |
| Bannink, F; Bauwens, L; Kirabira, P; Larok, R; van Hove, G | 1 |
| Bupp, CP; Dean, JH; Sarasua, SM; Stevenson, RE | 1 |
| Holzgreve, W; Kancherla, V; Oakley, GP; Obeid, R; Pietrzik, K; Wieser, S | 1 |
| Elkomy, R; Elsherbini, M; Fouad, M; Gaafar, H; Hatem, D; Helal, O; Maged, A; Ramadan, W | 1 |
| Bao, YH; Chang, SY; Li, R; Lu, XL; Qiu, ZY; Shangguan, SF; Wang, L; Wang, Z; Wu, LH; Xiao, P; Zhang, T; Zou, JZ | 1 |
| Atta, CA; Fiest, KM; Frolkis, AD; Jette, N; Kaplan, GG; Metcalfe, A; Pringsheim, T; Rajapakse, T; St Germaine-Smith, C | 1 |
| Bergman, JE; de Walle, HE; Otten, E; Verheij, JB | 1 |
| Berry, RJ; Grosse, SD; Kucik, JE; Mick Tilford, J; Waitzman, NJ | 1 |
| Brosnan, JT; Brosnan, ME; Copp, AJ; De Castro, SC; Greene, ND; Leung, KY; Mills, K; Sudiwala, S | 1 |
| Breimer, L; Nilsson, TK | 1 |
| Araki, A; Baba, T; Braimoh, T; Endo, T; Goudarzi, H; Ikeno, T; Itoh, K; Kishi, R; Kobayashi, S; Minakami, H; Miyashita, C; Sasaki, S; Sengoku, K; Yila, TA; Yoshioka, E | 1 |
| Adzick, NS; Chitty, LS; Copp, AJ; Fletcher, JM; Holmbeck, GN; Shaw, GM | 1 |
| Arth, A; Johnson, Q; Kancherla, V; Oakley, GP; Pachón, H; Zimmerman, S | 1 |
| Abbasher, LA; Abdullah, OM; Mohammed, IN; Omer, IM | 1 |
| Finnell, RH; Mason, CE; Ross, ME | 1 |
| Wilson, RD | 1 |
| Hiraoka, M; Kagawa, Y; Kageyama, M; Kontai, Y; Nishijima, C; Sakamoto, K; Yurimoto, M | 1 |
| Bauwens, L; Kancherla, V; Oakley, GP; Walani, SR; Warf, BC; Weakland, AP | 1 |
| Bocquet, A; Bresson, JL; Briend, A; Chouraqui, JP; Darmaun, D; Dupont, C; Frelut, ML; Ghisolfi, J; Girardet, JP; Goulet, O; Putet, G; Rieu, D; Rigo, J; Turck, D; Vidailhet, M | 1 |
| Bell, KN; Brent, RL; Oakley, GP | 1 |
| Crowley, M; De Wals, P; Evans, JA; Fernandez, B; Lee, NS; Lowry, RB; Niyonsenga, T; Sibbald, B; Tairou, F; Uh, SH; Van Allen, MI; Van den Hof, MC; Zimmer, P | 1 |
| Bell, KN; Oakley, GP | 2 |
| Blom, HJ; Coenen, MJ; den Heijer, M; Franke, B; Scheffer, H; Schijvenaars, MM; Steegers-Theunissen, RP; Vermeulen, SH | 1 |
| Chatzinikolaou, A; Hatzitolios, A; Ntaios, G; Savopoulos, C | 1 |
| Császár, J; Kozinszky, Z; Nagymajtényi, L; Paulik, E | 1 |
| Barcellos, LF; Briggs, FB; Carmichael, SL; Finnell, RH; Lammer, EJ; Lu, W; Shaw, GM; Yang, W; Zhu, H | 1 |
| Au, KS; Fletcher, JM; Lin, JI; Martinez, CA; Morrison, AC; Northrup, H; Tyerman, GH | 1 |
| Madhuri, R; Prasad, BB; Sharma, PS; Tiwari, MP | 1 |
| Flores, AL; Hamner, HC; Prue, CE | 1 |
| Bakker, MK; de Jong-van den Berg, LT; Jentink, J; Nijenhuis, CM; Wilffert, B | 1 |
| Canfield, MA; Chan, W; Langlois, PH; Lupo, PJ; Mitchell, LE; Symanski, E; Waller, DK | 1 |
| Alasfoor, D; Elsayed, MK; Mohammed, AJ | 1 |
| Castilla, EE; López-Camelo, JS; Orioli, IM | 1 |
| Claude, KM; Hawkes, M; Juvenal, KL | 1 |
| Calevo, MG; Cama, A; Capra, V; Crocetti, L; De Biasio, P; De Marco, P; Mascelli, S; Merello, E; Pastorino, D; Piatelli, G | 1 |
| Boshnjaku, V; Ichi, S; Mania-Farnell, B; Mayanil, CS; McLone, DG; Nakazaki, H; Singh, RM; Tomita, T; Xi, G | 1 |
| Colligs, A; Lindemann, M; Snowball, C; Yi, Y | 1 |
| Castilla, EE; Lima do Nascimento, R; López-Camelo, JS; Orioli, IM | 1 |
| Ahrens, K; Mitchell, AA; Werler, MM; Yazdy, MM | 1 |
| Honein, MA; Rasmussen, SA; Reefhuis, J | 1 |
| Bao, Y; Guo, J; Liu, C; Lu, X; Niu, B; Wang, F; Wang, J; Wang, L; Wu, L; Xie, H; Zhang, T; Zhao, H; Zou, J | 1 |
| Carmichael, SL; Gilbert, DA; Hardin, J; Hoffmann, TJ; Lammer, EJ; Lazaruk, K; Lipzen, A; Marini, NJ; Pennacchio, LA; Rine, J; Shaw, GM; Stein, JB; Witte, JS; Wright, C | 1 |
| Barboza Argüello, Mde L; Umaña Solís, LM | 1 |
| Zohn, IE | 1 |
| Awoyinka, BS; Rabiu, TB; Tiamiyu, LO | 1 |
| Baldino, CF; Borges, AL; Fujimori, E; Gomes, MN; Sato, AP | 1 |
| Edmonds, LD; Hobbs, CA; Kirby, RS; Levitt, M; Mai, CT; Meaney, FJ; Miller, LA; Sever, LE; Shaw, GM; Williams, LJ | 1 |
| Allan, G; Cogram, P; Copp, AJ; Greene, ND; Tesh, J; Tesh, S; Wade, A | 1 |
| Erickson, JD | 1 |
| Alvarez, CG; Ayala, JL; Bárcenas, M; Campos, Mdel R; Castro, RN; Domínguez, AS; García, JR; Garza, MT; González, MT; Herrera, RH; Limón, A; López, AG; López, RA; Martínez de Villarreal, L; Martínez, JG; Nuñez, RH; Pérez, JZ; Ramírez, JL; Sánchez, JM; Vázquez, PA; Villarreal, JJ | 1 |
| Arbour, L; Christensen, B; Delormier, T; Forbes, P; Gilfix, B; Kovitch, I; Morel, J; Platt, R; Rozen, R | 1 |
| Oakley, G; Omenn, G; Wald, N | 1 |
| Haddow, JE; Palomaki, GE; Williams, J | 1 |
| Frey, L; Hauser, WA | 1 |
| Finnell, RH; Gould, A; Spiegelstein, O | 1 |
| Finnell, RH; Lammer, EJ; Shaw, GM; Volcik, KA; Zhu, H | 1 |
| Devlin, AM; Finnell, R; Halsted, CH; Leclerc, D; Morin, I; Rozen, R; Sabbaghian, N | 1 |
| Yerby, MS | 1 |
| Carmichael, SL; Nelson, V; Quach, T; Schaffer, DM; Selvin, S; Shaw, GM; Yang, W | 1 |
| Finnell, RH; Lammer, EJ; Laurent, C; Shaw, GM; Volcik, KA; Zhu, H | 1 |
| Cain, R; Canick, JA; Halliday, J; Lambert-Messerlian, G; Msall, ME; Palomaki, GE; Williams, J | 1 |
| Cook, M; Hoess, K; Jensen, LE; Mitchell, LE; Thorn, CF; Wall, AM; Whitehead, AS | 1 |
| Gooskens, RH; Groenen, PM; Peer, PG; Steegers-Theunissen, RP; van Rooij, IA; Zielhuis, GA | 1 |
| Bell, KN; Colditz, P; Oakley, GP; Weber, MB | 1 |
| Cotter, AM; Daly, SF | 1 |
| Edmonds, LD; Flores, A; Kirby, RS; Rasmussen, SA; Williams, LJ | 1 |
| Brent, RL; Oakley, GP | 1 |
| Finnell, RH; Lammer, EJ; Lu, W; Shaw, GM; Yang, W; Zhang, J; Zhu, H | 1 |
| Bol, KA; Collins, JS; Kirby, RS | 1 |
| Block, G; Malcoe, LH; Samuels, SJ; Schaffer, DM; Shaw, GM; Todoroff, K; Velie, EM | 1 |
| Eichholzer, M; Tönz, O; Zimmermann, R | 1 |
| Källén, B; Nikkilä, A; Rydhström, H | 1 |
| Padmanabhan, R | 1 |
| Takimoto, H; Tamura, T | 1 |
| Arredondo, P; Hernández, R; Martínez de Villarreal, LE; Villarreal, JZ | 1 |
| Bird, TM; Cleves, MA; Hobbs, CA; Reading, JA; Robbins, JM; Tilford, JM | 1 |
| Cortes, F; Grosse, SD; Hertrampf, E; Llanos, A; Pardo, A; Uauy, R | 1 |
| Correa, A; Gardner, BR; Strickland, MJ | 1 |
| Aguila R, A; Cid R, MP; Cifuentes O, L; García A, K; Godoy V, ML; Juárez H, ME; Melibosky R, F; Nazer H, J | 1 |
| Joó, JG; Papp, Z | 1 |
| Burren, KA; Chitty, LS; Copp, AJ; Doudney, K; Dunlevy, LP; Greene, ND; Scott, R; Stanier, P; Stojilkovic-Mikic, T | 1 |
| Cao, SP; Chau, DH; Kung, HF; Lin, MC; Liu, J; Yang, GZ; Zhou, JL | 1 |
| Flowers, BS; Hobbs, CA; Mosley, BS; Robbins, JM; Smith, V | 1 |
| Bower, CI; Miller, M; Oddy, WH; Payne, JM; Serna, P | 1 |
| Copp, AJ; de Castro, SC; Greene, ND; Gustavsson, P; Lad, D; Pauws, E; Stanier, P | 1 |
| Maruyama, T; Sato, H | 1 |
| Besser, LM; Cragan, JD; Williams, LJ | 1 |
| Browne, M; Croft, J; Harris, F; Harrop, L; Hayward, W; Page, V; Stockley, L; Swindells, J; Tedstone, A; Vernon, C | 1 |
| Boulet, SL; Canfield, MA; Collins, JS; Kirby, RS; Mai, C; Meyer, R; Mulinare, J; Robbins, JM; Yang, Q | 1 |
| Abrams, B; Carmichael, SL; Chen, BH; Selvin, S; Shaw, GM | 1 |
| Levene, MI; Lucock, MD; Wild, J | 1 |
| Blom, HJ; den Heyer, M; Eskes, TK; Frosst, P; Mariman, EC; Rozen, R; Steegers-Theunissen, RP; Trijbels, FJ; van den Heuvel, LP; van der Put, NM | 1 |
| Ausman, JI; Slavin, KV | 1 |
| Hunt, G; Oakeshott, P | 1 |
| Czeizel, E; Dudás, I | 1 |
| Cordero, JF; Erickson, JD; James, LM; Mulinare, J; Oakley, GP | 1 |
| Burk, DT; Mirkes, PE | 1 |
| Adams, MJ; Dickinson, CM; Oakley, GP | 1 |
| Edmonds, LD; Lary, JM | 1 |
| Klein, NW | 1 |
| Locke, MD; Sarwark, JF | 1 |
| Antal, R; Czeizel, E; Siffel, C | 1 |
| Chou, S; Forman, R; Hoffman, L; Koren, G; Parkin, P; Perelman, V; Singal, N | 1 |
| Bower, C; Stanley, FJ | 1 |
| Blom, HJ; den Heyer, M; Eskes, TK; Mariman, EC; Steegers-Theunissen, RP; Trijbels, FJ; van den Heuvel, LP; van der Put, NM | 1 |
| Cornel, MC; Erickson, JD | 1 |
| Koren, G | 1 |
| Krischer, J | 1 |
| Blom, HJ; De Graaf-Hess, A; Eskes, TK; Mariman, EC; Smeitink, JA; Steegers-Theunissen, RP; Thomas, CM; Trijbels, FJ; van der Put, NM | 1 |
| Li, Z; Wang, H | 1 |
| Barber, RC; Biela, TA; Finnell, RH; Greer, KA; Lacey, SW; Lammer, EJ; Shaw, GM; Wasserman, CR | 1 |
| Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Weir, DG; Whitehead, AS | 1 |
| Beekhuis, JR; Cornel, MC; de Walle, HE; Leurquin, P; Staal-Schreinemachers, AL | 1 |
| Eskes, TK | 2 |
| Finnell, RH; Lammer, EJ; Rozen, R; Shaw, GM; Wasserman, CR | 1 |
| Ermert, A; Koch, MC; Schröter, B; Stegmann, K; Ziegler, A | 1 |
| Scott, JM | 1 |
| Christensen, B; Rozen, R; Sibani, S; Tran, P; Weisberg, I | 1 |
| Kennedy, DS | 1 |
| Daskalakis, I; Levene, MI; Lucock, MD; Lumb, CH; Schorah, CJ | 1 |
| Finnell, RH; Gravel, RA; Lammer, EJ; Leclerc, D; Rozen, R; Shaw, GM; Todoroff, K | 1 |
| Bower, C; Kurinczuk, JJ; Stanley, FJ | 1 |
| Bradley, S; Cumming, FJ | 1 |
| Leader, S; Mallick, R | 1 |
| Bradaï, R; Chakroun, R; Siger, D | 1 |
| Czeizel, E | 1 |
| Freeman, NV; Rajab, A | 1 |
| Ritvanen, A | 1 |
| Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Weir, DG | 1 |
| Grillo, S; Insolia, G; Pepe, F; Pepe, P | 1 |
| Briggs, D; Daskalakis, I; Levene, M; Lucock, M; Yates, Z | 1 |
| Dobson, R | 1 |
| Barth, PG; Hirasing, RA | 1 |
| Brent, RL; Mattison, DR; Oakley, GP | 1 |
| Caufield, LA; Caulfield, LE; Gross, SM; Ireys, HT; Kinsman, SL | 1 |
| Boecker, J; Capra, V; Ermert, A; Finnell, RH; Koch, MC; Ngo, ET; Richter, B; Stegmann, K; Strehl, E | 1 |
| Copp, AJ; van Straaten, HW | 1 |
| Pawlak, AL; Strauss, E | 1 |
| Czakó, M; Horváth, A; Kosztolányi, G; Melegh, B; Morava, E; Tóth, G | 1 |
| Brouwer, IA; Eskes, TK; Gaytant, MA; Hautvast, JG; Steegers-Theunissen, RP; Thomas, CM; van der Put, NM; van Dusseldorp, M | 1 |
| Daskalakis, I; Hinkins, M; Lucock, M; Yates, Z | 1 |
| Bell, R; Halliday, J; Watson, L; Watson, M | 1 |
| Baker, MW; Finnell, RH; Lammer, EJ; Neri, E; Shaw, GM; Zhu, H | 1 |
| Gorman, C | 1 |
| de Jong-van den Berg, LT; de Walle, HE; Londeman, J; Postma, MJ; Veenstra, M | 1 |
| Bower, C; Miller, M; Rudy, E; Ryan, A | 1 |
| Jongbloet, PH; Pasker-de Jong, PC; Zielhuis, SA | 1 |
| Hall, MH | 1 |
| Emery, AE | 1 |
| Emery, AE; Timson, J; Watson-Williams, EJ | 1 |
| Woodard, JC | 1 |
39 review(s) available for folic acid and Cleft Spine
| Article | Year |
|---|---|
[Research progress on the etiology and pathogenesis of spina bifida].
Topics: Female; Folic Acid; Humans; Neural Tube Defects; Pregnancy; Prevalence; Spinal Dysraphism | 2021 |
Preventing birth defects, saving lives, and promoting health equity: an urgent call to action for universal mandatory food fortification with folic acid.
Topics: Anencephaly; Child; Female; Folic Acid; Food, Fortified; Health Equity; Humans; Infant; Pregnancy; Prevalence; Spinal Dysraphism | 2022 |
Birth prevalence of neural tube defects in eastern Africa: a systematic review and meta-analysis.
Topics: Anencephaly; Encephalocele; Female; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Prevalence; Spinal Dysraphism; United States | 2022 |
The role of neurosurgeons in global public health: the case of folic acid fortification of staple foods to prevent spina bifida.
Topics: Anencephaly; Child; Folic Acid; Food, Fortified; Humans; Neurosurgeons; Prevalence; Public Health; Spinal Dysraphism | 2023 |
Neurodevelopmental Implications on Urological Self-management Among People Living With Spina Bifida: A Practical Guide for Urology Providers.
Topics: Female; Folic Acid; Humans; Pregnancy; Self-Management; Spinal Dysraphism; Urology; Vitamins | 2023 |
Failure to fortify staple foods with folic acid-still public health malpractice.
Topics: Folic Acid; Humans; Neural Tube Defects; Prevalence; Public Health; Spinal Dysraphism | 2023 |
A case study of ReachAnother Foundation as a change champion for developing spina bifida neurosurgical care and advocating for primary prevention in Ethiopia.
Topics: Ethiopia; Folic Acid; Food, Fortified; Humans; Hydrocephalus; Infant, Newborn; Prevalence; Primary Prevention; Spinal Dysraphism | 2023 |
Transitioning care for adolescents with spina bifida in the US: challenges for management.
Topics: Adolescent; Adult; Anencephaly; Child; Folic Acid; Food, Fortified; Humans; Spina Bifida Cystica; Spinal Dysraphism; Transition to Adult Care; Young Adult | 2023 |
Spina bifida management in low- and middle-income countries - a comprehensive policy approach.
Topics: Developing Countries; Folic Acid; Humans; Hydrocephalus; Policy; Spinal Dysraphism | 2023 |
Folate fortification and supplementation in prevention of folate-sensitive neural tube defects: a systematic review of policy.
Topics: Dietary Supplements; Female; Folic Acid; Humans; Infant; Infant, Newborn; Male; Neural Tube Defects; Policy; Quality of Life; Spinal Dysraphism | 2020 |
Prevalence rates of spina bifida in Alberta, Canada: 2001-2015. Can we achieve more prevention?
Topics: Alberta; Anencephaly; Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Male; Neural Tube Defects; Pregnancy; Prevalence; Spinal Dysraphism | 2019 |
Global Birth Prevalence of Spina Bifida by Folic Acid Fortification Status: A Systematic Review and Meta-Analysis.
Topics: Female; Folic Acid; Food, Fortified; Global Health; Humans; Pregnancy; Prevalence; Spinal Dysraphism; Vitamin B Complex | 2016 |
Spina bifida.
Topics: Female; Folic Acid; Humans; Meningomyelocele; Pregnancy; Prenatal Care; Prenatal Diagnosis; Spinal Dysraphism | 2015 |
Genomic approaches to the assessment of human spina bifida risk.
Topics: Datasets as Topic; DNA, Intergenic; Female; Folic Acid; Gene-Environment Interaction; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Infant, Newborn; Open Reading Frames; Pregnancy; Prenatal Diagnosis; Risk; Spinal Dysraphism | 2017 |
Medical cost savings in Sakado City and worldwide achieved by preventing disease by folic acid fortification.
Topics: Adult; Cost-Benefit Analysis; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Infant, Newborn; Japan; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Infarction; Polymorphism, Genetic; Pregnancy; Prevalence; Recommended Dietary Allowances; Spinal Dysraphism | 2017 |
[Folic acid and prevention of neural tube closure defects: the question is not solved yet].
Topics: Adult; Aged; Animals; Breast Neoplasms; Clinical Trials as Topic; Cognition Disorders; Cohort Studies; Colorectal Neoplasms; Edible Grain; Female; Folic Acid; Food, Fortified; France; Humans; Infant, Newborn; Male; Middle Aged; Neural Tube Defects; Pregnancy; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Spinal Dysraphism; United States | 2008 |
The scientific basis for eliminating folic acid-preventable spina bifida: a modern miracle from epidemiology.
Topics: Anencephaly; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Food, Fortified; Global Health; Humans; Incidence; Infant, Newborn; Pregnancy; Prenatal Care; Primary Prevention; Program Evaluation; Spinal Dysraphism; Treatment Outcome | 2009 |
Economic burden of neural tube defects and impact of prevention with folic acid: a literature review.
Topics: Cost of Illness; Cost-Benefit Analysis; Female; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Prenatal Care; Prevalence; Spinal Dysraphism; Vitamin B Complex | 2011 |
Mouse as a model for multifactorial inheritance of neural tube defects.
Topics: Anencephaly; Animals; Disease Models, Animal; Folic Acid; Genetic Predisposition to Disease; Humans; Mice; Multifactorial Inheritance; Neural Tube Defects; Spinal Dysraphism | 2012 |
Epidemiology of neural tube defects.
Topics: Anencephaly; Cross-Cultural Comparison; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Genetic Heterogeneity; Global Health; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Prevalence; Recurrence; Risk Factors; Spinal Dysraphism | 2003 |
Pathobiology and genetics of neural tube defects.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Infant, Newborn; Mice; Mice, Neurologic Mutants; Neural Tube Defects; Pharmacogenetics; Pregnancy; Pregnancy Complications; Risk Factors; Spinal Dysraphism | 2003 |
Management issues for women with epilepsy: neural tube defects and folic acid supplementation.
Topics: Adult; Animals; Anticonvulsants; Carbamazepine; Cleft Lip; Cleft Palate; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Pregnancy Complications; Spinal Dysraphism; Valproic Acid | 2003 |
Scientific evidence supporting folic acid fortification of flour in Australia and New Zealand.
Topics: Anencephaly; Australia; Flour; Folic Acid; Food, Fortified; Humans; New Zealand; Spinal Dysraphism | 2004 |
Folic acid: a public-health challenge.
Topics: Adult; Diet; Female; Folic Acid; Food, Fortified; Health Education; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Public Health; Spinal Dysraphism | 2006 |
Etiology, pathogenesis and prevention of neural tube defects.
Topics: Anencephaly; Animals; Embryonic Development; Encephalocele; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Male; Models, Anatomic; Models, Biological; Neural Crest; Neural Tube Defects; Pregnancy; Spinal Dysraphism | 2006 |
[Practice of pharmaceutical care based on clinical pharmaceutical research in a community pharmacy].
Topics: Anencephaly; Antipsychotic Agents; Benzodiazepines; Biomedical Research; Dietary Supplements; Female; Folic Acid; Food-Drug Interactions; Health Promotion; Humans; Male; Olanzapine; Patient Education as Topic; Pharmaceutical Services; Pharmacies; Pharmacists; Pharmacokinetics; Pregnancy; Sex Characteristics; Smoking; Spinal Dysraphism | 2007 |
Spina bifida, anencephaly, and folic acid: what do they have to do with neurosurgery?
Topics: Anencephaly; Clinical Trials as Topic; Folic Acid; Folic Acid Deficiency; Humans; Neural Tube Defects; Spinal Dysraphism | 1995 |
Prevention of folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Centers for Disease Control and Prevention, U.S.; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Pregnancy; Spinal Dysraphism; United States | 1994 |
More folic acid for everyone, now.
Topics: Adult; Aged; Anencephaly; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Infant, Newborn; Male; Pregnancy; Risk Factors; Spinal Dysraphism; United States; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Orthopedic aspects of myelodysplasia in children.
Topics: Child; Folic Acid; Hematinics; Humans; Kyphosis; Meningomyelocele; Neural Tube Defects; Prognosis; Spinal Dysraphism | 1996 |
Issues in the prevention of spina bifida.
Topics: Female; Folic Acid; Food, Fortified; Health Education; Humans; Infant, Newborn; Neural Tube Defects; Preconception Care; Pregnancy; Spinal Dysraphism | 1996 |
Neural tube defects, vitamins and homocysteine.
Topics: Animals; Female; Folic Acid; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Rats; Spinal Dysraphism | 1998 |
From birth to conception. Open or closed.
Topics: Congenital Abnormalities; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Netherlands; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Spinal Dysraphism | 1998 |
Neural tube defects.
Topics: Female; Folic Acid; Humans; Incidence; Infant, Newborn; Male; Neural Tube Defects; Oman; Patient Selection; Pregnancy; Prenatal Care; Risk Factors; Spinal Dysraphism | 1999 |
[Neural tube defects and folic acid].
Topics: Administration, Oral; Dietary Supplements; Female; Finland; Folic Acid; Health Education; Humans; Incidence; Infant, Newborn; Neural Tube Defects; Pregnancy; Prenatal Care; Spinal Dysraphism; Treatment Outcome | 1996 |
[Spina bifida: prevention policy can be more effective].
Topics: Adult; Female; Folic Acid; Health Promotion; Humans; Mass Screening; Netherlands; Neuroprotective Agents; Pregnancy; Pregnancy Trimester, Second; Prevalence; Primary Prevention; Spinal Dysraphism; Ultrasonography, Prenatal | 2000 |
Curly tail: a 50-year history of the mouse spina bifida model.
Topics: Animals; Cell Division; Crosses, Genetic; Disease Models, Animal; Drug Resistance; Environment; Folic Acid; Mice; Mice, Mutant Strains; Mutation; Neural Tube Defects; Spinal Dysraphism; Tail | 2001 |
[Polymorphism of the methylenetetrahydrofolate reductase gene (MTHFR) and incidence of hyperhomocysteinemia-related diseases].
Topics: Folic Acid; Gene Expression Regulation, Enzymologic; Gene Frequency; Genetic Predisposition to Disease; Humans; Hyperhomocysteinemia; Incidence; Methylenetetrahydrofolate Dehydrogenase (NADP); Mutation; Polymorphism, Genetic; Risk Factors; Spinal Dysraphism | 2001 |
Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects.
Topics: Anencephaly; Female; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Prenatal Care; Spinal Dysraphism | 1992 |
5 trial(s) available for folic acid and Cleft Spine
| Article | Year |
|---|---|
[Prevention of the first occurrence of anencephaly and spina bifida with periconceptional multivitamin supplementation (conclusion)].
Topics: Adult; Anencephaly; Female; Fertilization; Folic Acid; Humans; Spinal Dysraphism | 1994 |
[Evaluation on the informed consent, effectiveness in improving the knowledge of congenital defects and use of vitamin among women in Mancheng County, Herbei province].
Topics: Adolescent; Adult; Anencephaly; Evaluation Studies as Topic; Female; Folic Acid; Health Education; Humans; Informed Consent; Spinal Dysraphism; Truth Disclosure | 1996 |
Homocysteine metabolism and effects of folic acid supplementation in patients affected with spina bifida.
Topics: Administration, Oral; Adolescent; Adult; Case-Control Studies; Female; Folic Acid; Hematinics; Homocysteine; Humans; Male; Middle Aged; Spinal Dysraphism; Treatment Outcome | 2000 |
The increasing knowledge of the role of periconceptional folate in Victorian women of child-bearing age: follow-up of a randomised community intervention trial.
Topics: Adolescent; Adult; Dietary Supplements; Female; Folic Acid; Food, Fortified; Health Education; Health Knowledge, Attitudes, Practice; Humans; Neural Tube Defects; Nutritional Sciences; Outcome Assessment, Health Care; Preconception Care; Pregnancy; Spinal Dysraphism; Victoria | 2001 |
Use of folic acid for prevention of spina bifida and other neural tube defects--1983-1991.
Topics: Anencephaly; Encephalocele; Female; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Pregnancy Outcome; Spinal Dysraphism | 1991 |
185 other study(ies) available for folic acid and Cleft Spine
| Article | Year |
|---|---|
Prevention and awareness of birth defects across the lifespan using examples from congenital heart defects and spina bifida.
Topics: Folic Acid; Heart Defects, Congenital; Humans; Longevity; Spinal Dysraphism | 2022 |
Folate deficiency disturbs PEG10 methylation modifications in human spina bifida.
Topics: Apoptosis Regulatory Proteins; DNA Methylation; DNA-Binding Proteins; Female; Folic Acid; Folic Acid Deficiency; Humans; Neural Tube Defects; Pregnancy; RNA-Binding Proteins; RNA, Messenger; Sarcoglycans; Spinal Dysraphism | 2022 |
Periconceptional folic acid use prevents both rare and common neural tube defects in China.
Topics: Anencephaly; China; Dietary Supplements; Female; Folic Acid; Humans; Male; Neural Tube Defects; Pregnancy; Spinal Dysraphism | 2022 |
Changes in Spina Bifida Lesion Level after Folic Acid Fortification in the US.
Topics: Female; Folic Acid; Food, Fortified; Humans; Live Birth; Pregnancy; Prevalence; Spinal Dysraphism | 2022 |
CIC missense variants contribute to susceptibility for spina bifida.
Topics: Animals; Female; Folate Receptor 1; Folic Acid; HeLa Cells; Humans; Mice; Mutation, Missense; Neural Tube Defects; NIH 3T3 Cells; Pregnancy; Repressor Proteins; Spinal Dysraphism | 2022 |
A global update on the status of prevention of folic acid-preventable spina bifida and anencephaly in year 2020: 30-Year anniversary of gaining knowledge about folic acid's prevention potential for neural tube defects.
Topics: Anencephaly; Anniversaries and Special Events; Child; Female; Flour; Folic Acid; Food, Fortified; Humans; Neural Tube Defects; Pregnancy; Spinal Dysraphism; Triticum | 2022 |
From autism to zoom®: Spina bifida advocacy, care, education, and research in a changing word.
Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Folic Acid; Humans; Infant; Neural Tube Defects; Prevalence; Spinal Dysraphism | 2022 |
Paediatricians as champions for ending folic acid-preventable spina bifida, anencephaly globally.
Topics: Anencephaly; Folic Acid; Food, Fortified; Humans; Spinal Dysraphism | 2022 |
Spina bifida folate fortification in Brazil, update 2022: a cross-sectional study.
Topics: Brazil; Cross-Sectional Studies; Flour; Folic Acid; Food, Fortified; Humans; Prevalence; Spinal Dysraphism; Triticum | 2023 |
Neurosurgeon-Led Advocacy for Folic Acid Fortification to Prevent Spina Bifida.
Topics: Anencephaly; Folic Acid; Humans; Neural Tube Defects; Neurosurgeons; Prevalence; Spinal Dysraphism | 2023 |
Prevented cases of neural tube defects and cost savings after folic acid fortification of flour in Brazil.
Topics: Brazil; Cost Savings; Female; Flour; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Prevalence; Spinal Dysraphism | 2023 |
Preventing spina bifida through folate fortification: a labor of love.
Topics: Folic Acid; Humans; Spinal Dysraphism | 2023 |
Neural tube defects: Prevalence, mortality, and maternal characteristics in two departmental hospitals in the northwestern region of Nicaragua, 2006-2018.
Topics: Anencephaly; Cross-Sectional Studies; Encephalocele; Female; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Nicaragua; Pregnancy; Prevalence; Spinal Dysraphism; Stillbirth | 2023 |
High potential for reducing folic acid-preventable spina bifida and anencephaly, and related stillbirth and child mortality, in Ethiopia.
Topics: Anencephaly; Child Mortality; Child, Preschool; Ethiopia; Female; Flour; Folic Acid; Food, Fortified; Humans; Infant; Infant, Newborn; Male; Neural Tube Defects; Pregnancy; Prevalence; Spinal Dysraphism; Stillbirth | 2019 |
Classifying by cause and preventing the many causes of spina bifida and anencephaly.
Topics: Anencephaly; Anticonvulsants; Diabetes Mellitus; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Hypoglycemic Agents; Insulin; Pregnancy; Protective Factors; Risk Assessment; Risk Factors; Spinal Dysraphism; Valproic Acid | 2020 |
Understanding the Mothers of Children with Spina Bifida and Hydrocephalus in Tanzania.
Topics: Adolescent; Adult; Anticonvulsants; Birth Setting; Consanguinity; Diet; Dietary Supplements; Educational Status; Encephalocele; Female; Folic Acid; Geography; Health Knowledge, Attitudes, Practice; Health Services Accessibility; HIV Infections; Hospitals; Humans; Hydrocephalus; Kwashiorkor; Meningomyelocele; Middle Aged; Mothers; Obesity, Maternal; Pregnancy; Pregnancy Complications, Infectious; Protein-Energy Malnutrition; Qualitative Research; Spinal Dysraphism; Surveys and Questionnaires; Tanzania; Unemployment; Young Adult; Zea mays | 2020 |
The Teratology Society adopts resolution on folic acid fortification.
Topics: Anencephaly; Folic Acid; Humans; Spinal Dysraphism; Teratology | 2020 |
Modeling shows high potential of folic acid-fortified salt to accelerate global prevention of major neural tube defects.
Topics: Anencephaly; Child; Folic Acid; Food, Fortified; Humans; Neural Tube Defects; Spinal Dysraphism | 2020 |
Maternal Inositol Status and Neural Tube Defects: A Role for the Human Yolk Sac in Embryonic Inositol Delivery?
Topics: Female; Folic Acid; Humans; Inositol; Neural Tube Defects; Pregnancy; Spinal Dysraphism; Yolk Sac | 2021 |
A 2019 global update on folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Child; Folic Acid; Food, Fortified; Humans; Neural Tube Defects; Spinal Dysraphism | 2021 |
Projected impact of mandatory food fortification with folic acid on neurosurgical capacity needed for treating spina bifida in Ethiopia.
Topics: Child; Ethiopia; Female; Flour; Folic Acid; Food, Fortified; Humans; Infant; Infant, Newborn; Pregnancy; Spinal Dysraphism | 2021 |
Food Fortification With Folic Acid for Prevention of Spina Bifida and Anencephaly: The Need for a Paradigm Shift in Evidence Evaluation for Policy-Making.
Topics: Adult; Anencephaly; Female; Folic Acid; Food, Fortified; Health Policy; Humans; Infant, Newborn; Male; Policy Making; Pregnancy; Public Health; Spinal Dysraphism | 2021 |
The International Society for Pediatric Neurosurgery resolution on mandatory folic acid fortification of staple foods for prevention of spina bifida and anencephaly and associated disability and child mortality.
Topics: Anencephaly; Child; Child Mortality; Folic Acid; Humans; Neural Tube Defects; Neurosurgery; Prevalence; Spinal Dysraphism | 2021 |
Periconceptional nonsteroidal anti-inflammatory drug use, folic acid intake, and the risk of spina bifida.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Female; Folic Acid; Humans; Infant; Pharmaceutical Preparations; Pregnancy; Spinal Dysraphism | 2021 |
An Inframe Trinucleotide Deletion in MTRR Exon 1 is Associated with the Risk of Spina Bifida.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Amino Acid Sequence; Cells, Cultured; Exons; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylation; Models, Molecular; Pregnancy; Pregnancy Complications; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Deletion; Spinal Dysraphism; Young Adult | 2017 |
Periconceptional maternal fever, folic acid intake, and the risk for neural tube defects.
Topics: Adult; Case-Control Studies; Female; Fever; Folic Acid; Humans; Mothers; Neural Tube Defects; Pregnancy; Risk Factors; Spinal Dysraphism; Vitamin B Complex; Young Adult | 2017 |
Total prevention of folic acid-preventable spina bifida and anencephaly would reduce child mortality in India: Implications in achieving Target 3.2 of the Sustainable Development Goals.
Topics: Anencephaly; Child Mortality; Child, Preschool; Female; Folic Acid; Humans; India; Infant; Infant Mortality; Infant, Newborn; Male; Spinal Dysraphism | 2018 |
Mood-Stabilizing Anticonvulsants, Spina Bifida, and Folate Supplementation: Commentary.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Dietary Supplements; Female; Folic Acid; Humans; Lamotrigine; Neural Tube Defects; Pregnancy; Pregnancy Complications; Spinal Dysraphism; Triazines; Valproic Acid | 2018 |
Countries with an immediate potential for primary prevention of spina bifida and anencephaly: Mandatory fortification of wheat flour with folic acid.
Topics: Anencephaly; Flour; Folic Acid; Food, Fortified; Geography; Humans; Primary Prevention; Spinal Dysraphism; Triticum | 2018 |
Postfolate spina bifida lesion level change.
Topics: Female; Folic Acid; Food, Fortified; Humans; Male; Spinal Dysraphism; Young Adult | 2018 |
Neural Tube Defects and Folic Acid Food Fortification in Europe.
Topics: Europe; Folic Acid; Food, Fortified; Humans; Neural Tube Defects; Prevalence; Spinal Dysraphism | 2018 |
A 2017 global update on folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Infant; Infant Mortality; Pregnancy; Prevalence; Spinal Dysraphism; Triticum; Zea mays | 2018 |
Reductions in child mortality by preventing spina bifida and anencephaly: Implications in achieving Target 3.2 of the Sustainable Development Goals in developing countries.
Topics: Anencephaly; Child; Child Mortality; Developing Countries; Female; Flour; Folic Acid; Folic Acid Deficiency; Food, Fortified; Genetic Diseases, X-Linked; Goals; Humans; Infant; Male; Neural Tube Defects; Pregnancy; Prevalence; Spinal Dysraphism; Sustainable Development; Triticum | 2019 |
An Audit of Neural Tube Defects in the Republic Of Ireland for 2012-2015.
Topics: Access to Information; Anencephaly; Clinical Audit; Dietary Supplements; Encephalocele; Female; Folic Acid; Health Education; Humans; Incidence; Infant, Newborn; Ireland; Neural Tube Defects; Pregnancy; Spinal Dysraphism; Stillbirth | 2018 |
High burden of neural tube defects in Tigray, Northern Ethiopia: Hospital-based study.
Topics: Adult; Cross-Sectional Studies; Ethiopia; Female; Folic Acid; Hospitals; Humans; Infant, Newborn; Live Birth; Neural Tube Defects; Population Surveillance; Pregnancy; Pregnancy Outcome; Spinal Dysraphism; Young Adult | 2018 |
Nation-wide failure of voluntary folic acid fortification of corn masa flour and tortillas with folic acid.
Topics: Adolescent; Adult; Anencephaly; Dietary Supplements; Female; Flour; Folic Acid; Folic Acid Deficiency; Food, Fortified; Hispanic or Latino; Humans; Male; Middle Aged; Nutritional Requirements; Prevalence; Social Media; Spinal Dysraphism; Surveys and Questionnaires; United States; Voluntary Programs; White People; Zea mays | 2019 |
Awareness of spina bifida among family of affected child. A cross sectional questionnaire.
Topics: Adolescent; Adult; Analgesics; Awareness; Cross-Sectional Studies; Female; Fever; Folic Acid; Health Education; Health Knowledge, Attitudes, Practice; Humans; Male; Medical History Taking; Meningocele; Meningomyelocele; Mothers; Plant Preparations; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Radiation Exposure; Saudi Arabia; Spina Bifida Occulta; Spinal Dysraphism; Surveys and Questionnaires; Young Adult | 2019 |
The impact of folic acid intake on the association among diabetes mellitus, obesity, and spina bifida.
Topics: Adult; Case-Control Studies; Diabetes Complications; Female; Folic Acid; Humans; Logistic Models; Obesity; Risk Factors; Spinal Dysraphism | 2013 |
Risk of spina bifida and maternal cigarette, alcohol, and coffee use during the first month of pregnancy.
Topics: Adolescent; Adult; Alcohol Drinking; Caffeine; Case-Control Studies; Coffee; Female; Folic Acid; Humans; Logistic Models; Pregnancy; Pregnancy Trimester, First; Risk Factors; Smoking; Spinal Dysraphism; Young Adult | 2013 |
[Changes in life styles of pregnant women and risks for having a pregnancy afflicted with spina bifida].
Topics: Adolescent; Adult; Diet; Dietary Supplements; Female; Folic Acid; Humans; Japan; Life Style; Pregnancy; Spinal Dysraphism; Surveys and Questionnaires | 2013 |
2012 Update on global prevention of folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Flour; Folic Acid; Food, Fortified; Global Health; Humans; Infant; Models, Statistical; Nutritional Requirements; Prevalence; Spinal Dysraphism | 2013 |
Risk factors for the occurrence of spina bifida (a case-control study) and the prevalence rate of spina bifida in Japan.
Topics: Anticonvulsants; Case-Control Studies; Female; Folic Acid; Humans; Infant, Low Birth Weight; Japan; Logistic Models; Odds Ratio; Pedigree; Pregnancy; Prevalence; Risk Factors; Spinal Dysraphism; Surveys and Questionnaires | 2013 |
[Effects of wheat flour fortification with folic acid on the prevalence of neural tube defects in Chile].
Topics: Anencephaly; Chile; Encephalocele; Flour; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Prevalence; Spinal Dysraphism | 2013 |
Estimate of the potential impact of folic acid fortification of corn masa flour on the prevention of neural tube defects.
Topics: Anencephaly; Black or African American; Flour; Folic Acid; Food, Fortified; Hispanic or Latino; Humans; Infant; Models, Statistical; Monte Carlo Method; Nutritional Requirements; Prevalence; Spinal Dysraphism; United States; White People; Zea mays | 2013 |
Neural tube defects in Costa Rica, 1987-2012: origins and development of birth defect surveillance and folic acid fortification.
Topics: Anencephaly; Costa Rica; Encephalocele; Female; Folic Acid; Food, Fortified; Humans; Infant; Infant, Newborn; Neural Tube Defects; Population Surveillance; Pregnancy; Prevalence; Registries; Spinal Dysraphism | 2015 |
Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects.
Topics: Animals; Disease Models, Animal; Folic Acid; Glutathione; Low Density Lipoprotein Receptor-Related Protein-6; Metabolome; Mice; Mice, Knockout; Neural Tube; Neural Tube Defects; Oxidation-Reduction; Oxidative Stress; Spinal Dysraphism | 2014 |
An integrative computational approach for prioritization of genomic variants.
Topics: Child; Female; Folic Acid; Genomics; Humans; Models, Molecular; Mutation; Pregnancy; Protein Conformation; Reduced Folate Carrier Protein; Software; Spinal Dysraphism | 2014 |
Updated estimates of neural tube defects prevented by mandatory folic Acid fortification - United States, 1995-2011.
Topics: Anencephaly; Black or African American; Female; Folic Acid; Food, Fortified; Health Policy; Hispanic or Latino; Humans; Infant, Newborn; Population Surveillance; Pregnancy; Spinal Dysraphism; United States; White People | 2015 |
Awareness of folic acid use increases its consumption, and reduces the risk of spina bifida.
Topics: Adult; Awareness; Case-Control Studies; Diet; Dietary Supplements; Female; Folic Acid; Food, Fortified; Health Policy; Humans; Infant, Newborn; Japan; Odds Ratio; Preconception Care; Pregnancy; Spinal Dysraphism; Surveys and Questionnaires | 2015 |
Prevention of spina bifida: folic acid intake during pregnancy in Gulu district, northern Uganda.
Topics: Adolescent; Adult; Data Collection; Dietary Supplements; Female; Folic Acid; Food, Fortified; Health Knowledge, Attitudes, Practice; Health Personnel; Humans; Preconception Care; Pregnancy; Prenatal Care; Spinal Dysraphism; Uganda; Young Adult | 2015 |
When folic acid fails: Insights from 20 years of neural tube defect surveillance in South Carolina.
Topics: Adult; Anencephaly; Black or African American; Dietary Supplements; Encephalocele; Female; Fertilization; Folic Acid; Hispanic or Latino; Humans; Male; Population Surveillance; Pregnancy; Prenatal Diagnosis; Recurrence; Risk; South Carolina; Spinal Dysraphism; White People | 2015 |
Preventable spina bifida and anencephaly in Europe.
Topics: Anencephaly; Dietary Supplements; Ethnicity; Europe; Female; Folic Acid; Food, Fortified; Humans; Live Birth; Pregnancy; Prevalence; Spinal Dysraphism; White People | 2015 |
Periconceptional risk factors of spina bifida among Egyptian population: a case-control study.
Topics: Adult; Anticonvulsants; Case-Control Studies; Cytomegalovirus Infections; Egypt; Female; Folic Acid; Humans; Hydrocephalus; Multivariate Analysis; Parity; Polyhydramnios; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Spinal Dysraphism; Vitamin B Complex | 2016 |
Sonic Hedgehog Signaling Affected by Promoter Hypermethylation Induces Aberrant Gli2 Expression in Spina Bifida.
Topics: Adult; Brain; Case-Control Studies; Chromatin; DNA Methylation; Female; Folic Acid; Gene Expression Regulation, Developmental; Hedgehog Proteins; Humans; Male; Nuclear Proteins; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Spinal Dysraphism; Transcription, Genetic; Zinc Finger Protein GLI1; Zinc Finger Protein Gli2 | 2016 |
Folic acid supplementation influences the distribution of neural tube defect subtypes: A registry-based study.
Topics: Anencephaly; Dietary Supplements; Female; Folic Acid; Humans; Male; Netherlands; Preconception Care; Pregnancy; Registries; Retrospective Studies; Risk Factors; Severity of Illness Index; Spinal Dysraphism; Treatment Outcome | 2016 |
Will the Eastern Mediterranean Region be the first to prevent all of folic acid-preventable spina bifida and anencephaly?
Topics: Anencephaly; Folic Acid; Food, Fortified; Humans; Mediterranean Region; Oman; Saudi Arabia; Spinal Dysraphism; Vitamin B Complex | 2016 |
Retrospective Assessment of Cost Savings From Prevention: Folic Acid Fortification and Spina Bifida in the U.S.
Topics: Cost Savings; Female; Folic Acid; Food, Fortified; Humans; Infant; Pregnancy; Prevalence; Retrospective Studies; Spinal Dysraphism | 2016 |
Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects.
Topics: Animals; Disease Models, Animal; Folic Acid; Formates; Mice; Nucleotides; Spinal Dysraphism | 2016 |
[Time to jubilate. Spina bifida can be prevented].
Topics: Female; Folic Acid; Folic Acid Deficiency; History, 20th Century; Humans; Pregnancy; Spinal Dysraphism | 2016 |
Predictors of folate status among pregnant Japanese women: the Hokkaido Study on Environment and Children's Health, 2002-2012.
Topics: Adolescent; Adult; Cotinine; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Humans; Japan; Nutritional Status; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prenatal Care; Risk Factors; Self Report; Smoking; Socioeconomic Factors; Spinal Dysraphism; Surveys and Questionnaires; Tobacco Smoke Pollution; Vitamin B Complex; Young Adult | 2016 |
A 2015 global update on folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Female; Folic Acid; Food, Fortified; Humans; Male; Spinal Dysraphism | 2016 |
Research: Prevalence of neural tube defects Khartoum, Sudan August 2014-July 2015.
Topics: Cross-Sectional Studies; Female; Folic Acid; Hospitals; Humans; Infant, Newborn; Intensive Care, Neonatal; Male; Meningomyelocele; Neural Tube Defects; Pregnancy; Prevalence; Spinal Dysraphism; Sudan; Surveys and Questionnaires | 2016 |
Supplémentation préconceptionnelle en acide folique / multivitamines pour la prévention primaire et secondaire des anomalies du tube neural et d'autres anomalies congénitales sensibles à l'acide folique.
Topics: Congenital Abnormalities; Evidence-Based Practice; Female; Folic Acid; Humans; Infant, Newborn; Meningomyelocele; Micronutrients; Neural Tube Defects; Practice Guidelines as Topic; Preconception Care; Pregnancy; Spinal Dysraphism; Vitamins | 2016 |
Scorecard for spina bifida research, prevention, and policy - A development process.
Topics: Biomedical Research; Folic Acid; Global Health; Health Policy; Humans; Population Surveillance; Quality of Life; Spinal Dysraphism | 2017 |
Bio-monitoring the elimination of folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Female; Folic Acid; Health Surveys; Humans; Pregnancy; Spinal Dysraphism; Vitamin B Complex | 2008 |
Spina bifida before and after folic acid fortification in Canada.
Topics: Canada; Female; Folic Acid; Food, Fortified; Humans; Male; Pregnancy; Prevalence; Retrospective Studies; Spinal Dysraphism | 2008 |
Update on prevention of folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Dietary Supplements; Female; Flour; Folic Acid; Food, Fortified; Global Health; Humans; Nutritional Requirements; Pregnancy; Program Evaluation; Spinal Dysraphism; Triticum; Zea mays | 2009 |
Racial/ethnic differences in the birth prevalence of spina bifida - United States, 1995-2005.
Topics: Birth Certificates; Black People; Folic Acid; Food, Fortified; Hispanic or Latino; Humans; Infant, Newborn; Prevalence; Spinal Dysraphism; United States; Vitamin B Complex; White People | 2009 |
An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1).
Topics: Child; DNA (Cytosine-5-)-Methyltransferases; Female; Folic Acid; Genotype; Humans; Polymorphism, Genetic; Receptors, Cell Surface; Spinal Dysraphism | 2009 |
"Well done folate, the little boy was born healthy without spina bifida: but will he suffer a stroke when elderly?".
Topics: Aged; Folic Acid; Humans; Infant, Newborn; Male; Risk Factors; Spinal Dysraphism; Stroke | 2009 |
Preconceptional and prenatal predictors of folic acid intake in Hungarian pregnant women.
Topics: Adult; Age Factors; Anencephaly; Dietary Supplements; Female; Folic Acid; Health Surveys; Humans; Hungary; Life Style; Logistic Models; Patient Education as Topic; Preconception Care; Pregnancy; Prenatal Care; Retrospective Studies; Spinal Dysraphism | 2009 |
118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects.
Topics: Biological Transport; California; Case-Control Studies; Folic Acid; Genetic Predisposition to Disease; Genotype; Haplotypes; Heart Defects, Congenital; Humans; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Spinal Dysraphism | 2009 |
Genetic association study of putative functional single nucleotide polymorphisms of genes in folate metabolism and spina bifida.
Topics: Cystathionine beta-Synthase; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Spinal Dysraphism; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 2009 |
Development of a highly sensitive and selective hyphenated technique (molecularly imprinted micro-solid phase extraction fiber-molecularly imprinted polymer fiber sensor) for ultratrace analysis of folic acid.
Topics: Biomarkers; Blood Chemical Analysis; Carbon; Folic Acid; Humans; Membranes, Artificial; Molecular Imprinting; Particle Size; Polymers; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Microextraction; Spinal Dysraphism; Surface Properties | 2010 |
Effects of folic acid awareness on knowledge and consumption for the prevention of birth defects among Hispanic women in several U.S. Communities.
Topics: Adult; Anencephaly; Awareness; Dietary Supplements; Female; Folic Acid; Health Knowledge, Attitudes, Practice; Health Promotion; Health Surveys; Hispanic or Latino; Humans; Neural Tube Defects; Patient Acceptance of Health Care; Pregnancy; Spinal Dysraphism; United States; Vitamin B Complex; Young Adult | 2010 |
Folic acid-preventable spina bifida: a good start but much to be done.
Topics: Developed Countries; Female; Folic Acid; Humans; Spinal Dysraphism | 2010 |
Does folic acid use decrease the risk for spina bifida after in utero exposure to valproic acid?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Humans; Infant, Newborn; Pregnancy; Pregnancy Trimester, First; Risk Factors; Spinal Dysraphism; Valproic Acid | 2010 |
Polytomous logistic regression as a tool for exploring heterogeneity across birth defect subtypes: an example using anencephaly and spina bifida.
Topics: Anencephaly; Body Mass Index; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Genetic Association Studies; Hispanic or Latino; Humans; Infant; Logistic Models; Male; Phenotype; Risk Factors; Spinal Dysraphism | 2010 |
Spina bifida and birth outcome before and after fortification of flour with iron and folic acid in Oman.
Topics: Diet Surveys; Female; Flour; Folic Acid; Food, Fortified; Hematinics; Humans; Incidence; Iron; Morbidity; National Health Programs; Neural Tube Defects; Nutrition Policy; Oman; Pregnancy; Pregnancy Outcome; Program Evaluation; Spinal Dysraphism; Vitamin B Complex | 2010 |
Folic acid flour fortification: impact on the frequencies of 52 congenital anomaly types in three South American countries.
Topics: Anencephaly; Argentina; Arm; Brazil; Chile; Congenital Abnormalities; Flour; Folic Acid; Food, Fortified; Heart Septal Defects; Humans; Infant, Newborn; Leg; Legislation, Food; Neural Tube Defects; Prevalence; Spinal Dysraphism | 2010 |
Applying a knowledge-to-action framework for primary prevention of spina bifida in tropical Africa.
Topics: Adolescent; Adult; Audiovisual Aids; Child, Preschool; Cost of Illness; Democratic Republic of the Congo; Dietary Supplements; Female; Focus Groups; Folic Acid; Health Knowledge, Attitudes, Practice; Humans; Infant; Infant, Newborn; Male; Maternal Health Services; Maternal Nutritional Physiological Phenomena; Patient Education as Topic; Pregnancy; Retrospective Studies; Spinal Dysraphism; Young Adult | 2012 |
Maternal periconceptional factors affect the risk of spina bifida-affected pregnancies: an Italian case-control study.
Topics: Adult; Alcohol Drinking; Case-Control Studies; Diet; Dietary Supplements; Female; Folic Acid; Humans; Italy; Life Style; Maternal Age; Multivariate Analysis; Odds Ratio; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Smoking; Socioeconomic Factors; Spinal Dysraphism; Surveys and Questionnaires; Vitamin B Complex | 2011 |
Fetal neural tube stem cells from Pax3 mutant mice proliferate, differentiate, and form synaptic connections when stimulated with folic acid.
Topics: Animals; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Embryo, Mammalian; Fetal Stem Cells; Fetus; Folic Acid; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Homozygote; Mice; Mice, Knockout; Neural Stem Cells; Neural Tube; Neurons; Paired Box Transcription Factors; PAX3 Transcription Factor; Receptor, Fibroblast Growth Factor, Type 4; Signal Transduction; Spinal Dysraphism; Synapses | 2012 |
Effects of folic acid fortification on spina bifida prevalence in Brazil.
Topics: Brazil; Cross-Sectional Studies; Female; Folic Acid; Food, Fortified; Humans; Prevalence; Spinal Dysraphism | 2011 |
Folic acid intake and spina bifida in the era of dietary folic acid fortification.
Topics: Adolescent; Adult; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Infant; Infant, Newborn; Logistic Models; Odds Ratio; Ontario; Pregnancy; Prenatal Nutritional Physiological Phenomena; Risk Factors; Spinal Dysraphism; United States; Young Adult | 2011 |
Prenatal versus postnatal repair of myelomeningocele.
Topics: Body Mass Index; Fetal Diseases; Fetus; Folic Acid; Food, Fortified; Humans; Infant Care; Infant, Newborn; Meningomyelocele; Risk Factors; Spinal Dysraphism | 2011 |
Glutamate carboxypeptidase II gene polymorphisms and neural tube defects in a high-risk Chinese population.
Topics: Adult; Anencephaly; Asian People; Aspartic Acid; Case-Control Studies; China; Dipeptides; Encephalocele; Female; Folic Acid; Gene Frequency; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Neural Tube Defects; Polymorphism, Genetic; Risk Factors; Spinal Dysraphism; Young Adult | 2012 |
A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis.
Topics: Alleles; Case-Control Studies; Folic Acid; Gene Expression Profiling; Genetic Predisposition to Disease; Hispanic or Latino; Homocysteine; Humans; Infant, Newborn; Metabolic Networks and Pathways; Models, Genetic; Mutation; Purines; Risk Factors; Spinal Dysraphism; White People | 2011 |
[Impact of the fortification of food with folic acid on neural tube defects in Costa Rica].
Topics: Anencephaly; Animals; Costa Rica; Encephalocele; Female; Flour; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Male; Milk; Morbidity; Neural Tube Defects; Oryza; Prevalence; Registries; Retrospective Studies; Spinal Dysraphism | 2011 |
Awareness of spina bifida and periconceptional use of folic acid among pregnant women in a developing economy.
Topics: Adolescent; Adult; Developing Countries; Educational Status; Female; Folic Acid; Gestational Age; Health Knowledge, Attitudes, Practice; Health Promotion; Health Surveys; Humans; Middle Aged; Neural Tube Defects; Nigeria; Pregnancy; Socioeconomic Factors; Spinal Dysraphism; Superstitions; Surveys and Questionnaires; Vitamins; Young Adult | 2012 |
[Prevalence and spatial distribution of neural tube defects in São Paulo State, Brazil, before and after folic acid flour fortification].
Topics: Adolescent; Adult; Anencephaly; Brazil; Cross-Sectional Studies; Encephalocele; Female; Flour; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Pregnancy; Prenatal Care; Prevalence; Residence Characteristics; Socioeconomic Factors; Spinal Dysraphism; Young Adult | 2013 |
Prevalence of spina bifida and anencephaly during the transition to mandatory folic acid fortification in the United States.
Topics: Anencephaly; Folic Acid; Food, Fortified; Humans; Meta-Analysis as Topic; Prevalence; Public Health; Spinal Dysraphism; United States | 2002 |
D-chiro-inositol is more effective than myo-inositol in preventing folate-resistant mouse neural tube defects.
Topics: Administration, Oral; Animals; Drug Resistance; Embryonic and Fetal Development; Female; Folic Acid; In Vitro Techniques; Injections, Subcutaneous; Inositol; Mice; Mice, Neurologic Mutants; Neural Tube Defects; Pregnancy; Pregnancy Outcome; Spinal Dysraphism | 2002 |
Folic acid and prevention of spina bifida and anencephaly. 10 years after the U.S. Public Health Service recommendation.
Topics: Anencephaly; Dietary Supplements; Female; Folic Acid; Humans; Practice Guidelines as Topic; Preconception Care; Pregnancy; Prenatal Care; Spinal Dysraphism; United States; United States Public Health Service | 2002 |
Decline of neural tube defects cases after a folic acid campaign in Nuevo León, México.
Topics: Anencephaly; Dietary Supplements; Encephalocele; Female; Folic Acid; Humans; Male; Mexico; Neural Tube Defects; Population Surveillance; Pregnancy; Pregnancy Outcome; Prenatal Care; Prevalence; Registries; Rural Population; Sex Factors; Spinal Dysraphism; Urban Population | 2002 |
Folate delivers head-to-toe health advantages. The B vitamin that benefits unborn babies may also protect the hearts and minds (and colons) of adults.
Topics: Alzheimer Disease; Anencephaly; Colonic Neoplasms; Female; Folic Acid; Heart Diseases; Homocysteine; Humans; Male; Pregnancy; Spinal Dysraphism; Stroke | 2002 |
Spina bifida, folate metabolism, and dietary folate intake in a Northern Canadian aboriginal population.
Topics: Adult; Arctic Regions; Canada; Case-Control Studies; Diet; Female; Folic Acid; Humans; Indians, North American; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Spinal Dysraphism | 2002 |
Provide the citizens of New Zealand the miracle of folic acid fortification.
Topics: Adult; Anencephaly; Female; Folic Acid; Folic Acid Deficiency; Food Supply; Food, Fortified; Humans; Infant, Newborn; New Zealand; Pregnancy; Spinal Dysraphism | 2003 |
Comparing the observed and predicted effectiveness of folic acid fortification in preventing neural tube defects.
Topics: Anencephaly; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Prevalence; Reproducibility of Results; Spinal Dysraphism; United States | 2003 |
Evaluation of infant methylenetetrahydrofolate reductase genotype, maternal vitamin use, and risk of high versus low level spina bifida defects.
Topics: California; Case-Control Studies; Dietary Supplements; DNA; Female; Folic Acid; Genetic Predisposition to Disease; Genome, Human; Genotype; Humans; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymerase Chain Reaction; Pregnancy; Risk; Spinal Dysraphism | 2003 |
Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk.
Topics: Alleles; Canada; Carrier Proteins; Female; Folic Acid; Glutamate Carboxypeptidase II; Humans; Membrane Proteins; Membrane Transport Proteins; Mutation; Neural Tube Defects; Polymorphism, Genetic; Pregnancy; Risk Factors; Spinal Dysraphism | 2003 |
Neural tube defects associated with maternal periconceptional dietary intake of simple sugars and glycemic index.
Topics: Adult; Analysis of Variance; Anencephaly; Body Mass Index; Body Weight; Case-Control Studies; Diet; Dietary Sucrose; Female; Folic Acid; Fructose; Glucose; Glycemic Index; Humans; Neural Tube Defects; Preconception Care; Pregnancy; Risk Factors; Spinal Dysraphism | 2003 |
Associations between polymorphisms within the thymidylate synthase gene and spina bifida.
Topics: 3' Untranslated Regions; Case-Control Studies; DNA Primers; Exons; Folic Acid; Genotype; Homocysteine; Homozygote; Humans; Infant, Newborn; Models, Biological; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Spinal Dysraphism; Thymidylate Synthase | 2003 |
Spina bifida and anencephaly before and after folic acid mandate--United States, 1995-1996 and 1999-2000.
Topics: Anencephaly; Dietary Supplements; Folic Acid; Food, Fortified; Humans; Nutritional Requirements; Preconception Care; Prenatal Care; Spinal Dysraphism; United States | 2004 |
Effect of folic acid fortification on prevalence of neural tube defects in Rhode Island.
Topics: Anencephaly; Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Neural Tube Defects; Pregnancy; Rhode Island; Spinal Dysraphism; Time Factors | 2004 |
A common ABCC2 promoter polymorphism is not a determinant of the risk of spina bifida.
Topics: ATP-Binding Cassette Transporters; Folic Acid; Genetic Variation; Homocysteine; Humans; Likelihood Functions; Linear Models; Multidrug Resistance-Associated Protein 2; Neural Tube Defects; Pedigree; Polymorphism, Genetic; Promoter Regions, Genetic; Retrospective Studies; Risk Factors; Spinal Dysraphism | 2004 |
Marginal maternal vitamin B12 status increases the risk of offspring with spina bifida.
Topics: Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Infant; Male; Pregnancy; Risk Assessment; Risk Factors; Spinal Dysraphism; Vitamin B 12; Vitamin B 6 | 2004 |
Neural tube defects: is a decreasing prevalence associated with a decrease in severity?
Topics: Anencephaly; Dietary Supplements; Encephalocele; Folic Acid; Humans; Infant, Newborn; Ireland; Neural Tube Defects; Spinal Dysraphism | 2005 |
Euthanasia in severely ill newborns.
Topics: Euthanasia; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Netherlands; Practice Guidelines as Topic; Spinal Dysraphism | 2005 |
Decline in the prevalence of spina bifida and anencephaly by race/ethnicity: 1995-2002.
Topics: Anencephaly; Black People; Ethnicity; Female; Folic Acid; Food, Fortified; Hispanic or Latino; Humans; Pregnancy; Prenatal Care; Prevalence; Puerto Rico; Racial Groups; Spinal Dysraphism; United States; White People | 2005 |
The Food and Drug Administration must require the addition of more folic acid in "enriched" flour and other grains.
Topics: Anencephaly; Edible Grain; Female; Flour; Folic Acid; Food, Fortified; Humans; Pregnancy; Prenatal Care; Spinal Dysraphism; United States; United States Food and Drug Administration; Vitamin B Complex | 2005 |
A known functional polymorphism (Ile120Val) of the human PCMT1 gene and risk of spina bifida.
Topics: Adult; California; Case-Control Studies; Cohort Studies; Dietary Supplements; Folic Acid; Genetic Predisposition to Disease; Hispanic or Latino; Humans; Infant, Newborn; Polymorphism, Genetic; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Risk; Spinal Dysraphism; White People | 2006 |
Survival of infants with neural tube defects in the presence of folic acid fortification.
Topics: Dietary Supplements; Encephalocele; Female; Flour; Folic Acid; Food, Fortified; Humans; Infant; Infant, Newborn; Neural Tube Defects; Pregnancy; Prenatal Care; Spinal Dysraphism; Survival Rate; Vitamin B Complex | 2006 |
Understanding the increased risk of neural tube defect-affected pregnancies among Mexico-born women in California: immigration and anthropometric factors.
Topics: Adolescent; Adult; Age Distribution; Anencephaly; Anthropometry; California; Dietary Supplements; Emigration and Immigration; Epidemiologic Methods; Female; Folic Acid; Humans; Infant, Newborn; Mexico; Neural Tube Defects; Phenotype; Pregnancy; Pregnancy Complications; Socioeconomic Factors; Spinal Dysraphism; Weight Gain | 2006 |
The incidence of spina bifida in Sweden 1973-2003: the effect of prenatal diagnosis.
Topics: Abortion, Therapeutic; Birth Rate; Chi-Square Distribution; Dietary Supplements; Efficiency, Organizational; Folic Acid; Gestational Age; Health Services Needs and Demand; Humans; Incidence; Infant, Newborn; Mass Screening; Population Surveillance; Prenatal Diagnosis; Prevalence; Registries; Research Design; Residence Characteristics; Sensitivity and Specificity; Spinal Dysraphism; Sweden | 2006 |
Increasing trend of spina bifida and decreasing birth weight in relation to declining body-mass index of young women in Japan.
Topics: Birth Weight; Body Image; Body Mass Index; Female; Folic Acid; Humans; Infant, Newborn; Japan; Life Style; Prevalence; Risk Factors; Smoking; Smoking Cessation; Spinal Dysraphism; Weight Loss; Young Adult | 2006 |
Weekly administration of folic acid and epidemiology of neural tube defects.
Topics: Anencephaly; Encephalocele; Female; Folic Acid; Health Promotion; Humans; Infant, Newborn; Male; Maternal Welfare; Mexico; Neural Tube Defects; Public Health; Spinal Dysraphism; Vitamin B Complex | 2006 |
Hospitalizations of newborns with folate-sensitive birth defects before and after fortification of foods with folic acid.
Topics: Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Infant, Newborn; Male; Patient Admission; Patient Discharge; Prevalence; Retrospective Studies; Spinal Dysraphism; United States | 2006 |
Tracking the prevention of folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Female; Folic Acid; Food, Fortified; Humans; Pregnancy; Prevalence; Program Evaluation; Spinal Dysraphism | 2006 |
Cost-effectiveness of a folic acid fortification program in Chile.
Topics: Aged; Anencephaly; Chile; Cost-Benefit Analysis; Costs and Cost Analysis; Female; Fetal Death; Folic Acid; Food, Fortified; Humans; Incidence; Male; Program Evaluation; Quality-Adjusted Life Years; Spinal Dysraphism | 2007 |
Application of the automated spatial surveillance program to birth defects surveillance data.
Topics: Automation; Congenital Abnormalities; Female; Fetal Diseases; Folic Acid; Humans; Neural Tube Defects; Population Surveillance; Pregnancy; Prevalence; Software; Spinal Dysraphism; Time Factors | 2007 |
[Effects of folic acid fortification in the rates of malformations at birth in Chile].
Topics: Anencephaly; Chi-Square Distribution; Chile; Congenital Abnormalities; Dietary Supplements; Flour; Folic Acid; Food, Fortified; Hernia, Diaphragmatic; Humans; Infant, Newborn; Live Birth; Prevalence; Spinal Dysraphism; Stillbirth | 2007 |
[Risk of recurrence in major craniospinal malformations between 1976 and 2005].
Topics: Anencephaly; Folic Acid; Genetic Counseling; Humans; Hungary; Nervous System Malformations; Neural Tube Defects; Recurrence; Retrospective Studies; Risk Assessment; Risk Factors; Spinal Dysraphism | 2007 |
When will we eliminate folic acid-preventable spina bifida?
Topics: Adult; Canada; Female; Flour; Folic Acid; Food, Fortified; Humans; Neural Tube Defects; Pregnancy; Spinal Dysraphism; United States; United States Food and Drug Administration; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2007 |
Abnormal folate metabolism in foetuses affected by neural tube defects.
Topics: Anencephaly; Animals; Antimetabolites; Deoxyuridine; Female; Ferredoxin-NADP Reductase; Fetal Diseases; Fetus; Fibroblasts; Folic Acid; Genotype; Humans; Methylation; Mice; Neural Tube Defects; NIH 3T3 Cells; Polymorphism, Genetic; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Spinal Dysraphism | 2007 |
Prevalence of neural tube defects in economically and socially deprived area of China.
Topics: Adult; Age Factors; Anencephaly; Birth Weight; China; Congenital Abnormalities; Encephalocele; Female; Folic Acid; Gestational Age; Humans; Infant, Low Birth Weight; Infant, Newborn; Maternal Age; Neural Tube Defects; Poverty Areas; Pregnancy; Spinal Dysraphism | 2007 |
Folic acid and the decline in neural tube defects in Arkansas.
Topics: Anencephaly; Arkansas; Dietary Supplements; Folic Acid; Health Education; Humans; Neural Tube Defects; Spinal Dysraphism | 2007 |
Awareness and consumption of folate-fortified foods by women of childbearing age in Western Australia.
Topics: Adult; Awareness; Female; Folic Acid; Food Labeling; Food, Fortified; Humans; Neural Tube Defects; Pregnancy; Spinal Dysraphism; Surveys and Questionnaires; Vitamin B Complex; Western Australia | 2007 |
Increased expression of Grainyhead-like-3 rescues spina bifida in a folate-resistant mouse model.
Topics: Animals; Chromosomes, Artificial, Bacterial; DNA-Binding Proteins; Folic Acid; Gene Expression; Mice; Mice, Transgenic; Mitotic Index; Mutation; Neural Tube; RNA, Messenger; Spinal Dysraphism; Transcription Factors | 2007 |
Interpreting changes in the epidemiology of anencephaly and spina bifida following folic acid fortification of the U.S. grain supply in the setting of long-term trends, Atlanta, Georgia, 1968-2003.
Topics: Anencephaly; Ethnicity; Female; Folic Acid; Food, Fortified; Georgia; Humans; Infant; Male; Prevalence; Sex Distribution; Spinal Dysraphism; Time Factors; United States | 2007 |
Fortification of selected foodstuffs with folic acid in the UK: consumer research carried out to inform policy recommendations.
Topics: Consumer Behavior; Consumer Organizations; Demography; Female; Folic Acid; Food, Fortified; Health Knowledge, Attitudes, Practice; Health Policy; Health Surveys; Humans; Interviews as Topic; Neural Tube Defects; Nutritional Status; Public Health; Spinal Dysraphism; Surveys and Questionnaires; United Kingdom | 2008 |
Trends in the postfortification prevalence of spina bifida and anencephaly in the United States.
Topics: Anencephaly; Black People; Ethnicity; Folic Acid; Food, Fortified; Hispanic or Latino; Humans; Infant, Newborn; Population Surveillance; Prevalence; Spinal Dysraphism; United States; White People | 2008 |
NTD prevalences in central California before and after folic acid fortification.
Topics: Adult; Anencephaly; California; Female; Folic Acid; Follow-Up Studies; Food, Fortified; Humans; Neural Tube Defects; Pregnancy; Prenatal Care; Prevalence; Spinal Dysraphism; Stillbirth | 2008 |
Enzyme defect as a risk factor for spina bifida.
Topics: Female; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Risk Factors; Spinal Dysraphism | 1995 |
Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida.
Topics: Adult; Female; Folic Acid; Gene Frequency; Homocysteine; Homozygote; Humans; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Risk Factors; Spinal Dysraphism | 1995 |
Prevention of neural tube defects.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Female; Folic Acid; Humans; Neural Tube Defects; Pregnancy; Spinal Dysraphism; Valproic Acid | 1994 |
Summary of the 1993 Teratology Society Public Affairs Committee Symposium: "Folic Acid Prevention of Neural Tube Defects: Public Policy Issues".
Topics: Anencephaly; Female; Folic Acid; Humans; Neural Tube Defects; Organizational Policy; Pregnancy; Societies, Scientific; Spinal Dysraphism | 1994 |
From the Centers for Disease Control and Prevention. Recommendations for use of folic acid to reduce number of spina bifida cases and other neural tube defects.
Topics: Anencephaly; Female; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Prenatal Care; Spinal Dysraphism | 1993 |
Folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Diet; Female; Folic Acid; Humans; Pregnancy; Prenatal Care; Spinal Dysraphism; Vitamins | 1993 |
Prevalence of spina bifida at birth--United States, 1983-1990: a comparison of two surveillance systems.
Topics: Female; Folic Acid; Humans; Infant, Newborn; Male; Neural Tube Defects; Population Surveillance; Pregnancy; Prenatal Care; Prevalence; Spinal Dysraphism; United States | 1996 |
Folic acid and prevention of spina bifida.
Topics: Folic Acid; Humans; Spinal Dysraphism | 1996 |
National Health and Medical Research Council. Revised statement on the relationship between dietary folic acid and neural tube defects such as spina bifida.
Topics: Anticonvulsants; Drug Interactions; Female; Folic Acid; Food, Fortified; Health Education; Humans; Neural Tube Defects; Pregnancy; Risk Factors; Spinal Dysraphism | 1995 |
[Prevention of anencephaly-spina bifida].
Topics: Anencephaly; Family Planning Services; Female; Folic Acid; Humans; Hungary; Infant, Newborn; Maternal Health Services; Pregnancy; Spina Bifida Cystica; Spinal Dysraphism | 1996 |
Folic acid and prevention of neural tube defects: a study of Canadian mothers of infants with spina bifida.
Topics: Canada; Diet; Female; Folic Acid; Health Education; Humans; Infant; Male; Neural Tube Defects; Pregnancy; Risk Factors; Spinal Dysraphism | 1996 |
Child bearing age women and folic acid--what's the connection?
Topics: Adult; Central Nervous System; Clinical Trials as Topic; Female; Folic Acid; Humans; Pregnancy; Spinal Dysraphism | 1996 |
Decreased methylene tetrahydrofolate reductase activity due to the 677C-->T mutation in families with spina bifida offspring.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Aged; Child; Cysteine; Female; Folic Acid; Genetic Linkage; Genotype; Homocysteine; Homozygote; Humans; Lod Score; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Netherlands; Oxidoreductases; Point Mutation; Risk Factors; Spinal Dysraphism; Vitamin B 12 | 1996 |
Comparison of national policies on periconceptional use of folic acid to prevent spina bifida and anencephaly (SBA).
Topics: Anencephaly; Female; Fertilization; Folic Acid; Food, Fortified; Health Policy; Health Promotion; Humans; Infant, Newborn; Nutrition Policy; Pregnancy; Spinal Dysraphism | 1997 |
Periconception folic acid supplementation. Knowledge and practice of Canadian family physicians.
Topics: Family Practice; Female; Folic Acid; Health Knowledge, Attitudes, Practice; Humans; Male; Ontario; Preconception Care; Spinal Dysraphism; Surveys and Questionnaires | 1997 |
Knowledge about folic acid and the prevention of neural tube defects in two general practice populations.
Topics: Adolescent; Adult; Family Practice; Female; Flour; Folic Acid; Food, Fortified; Humans; Patient Education as Topic; Pregnancy; Spinal Dysraphism; Suburban Population; Surveys and Questionnaires; Urban Population | 1997 |
Altered folate and vitamin B12 metabolism in families with spina bifida offspring.
Topics: Adolescent; Adult; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Risk; Spinal Dysraphism; Statistics, Nonparametric; Vitamin B 12 | 1997 |
Lack of association between mutations in the folate receptor-alpha gene and spina bifida.
Topics: Carrier Proteins; Case-Control Studies; Dietary Supplements; DNA Fingerprinting; Exons; Female; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Variation; Humans; Infant, Newborn; Male; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pregnancy; Pregnancy Outcome; Receptors, Cell Surface; Sequence Analysis, DNA; Spinal Dysraphism; Tetrahydrofolates | 1998 |
Whole-blood folate values in subjects with different methylenetetrahydrofolate reductase genotypes: differences between the radioassay and microbiological assays.
Topics: Biological Assay; Child, Preschool; Female; Folic Acid; Genotype; Humans; Lacticaseibacillus casei; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Radioligand Assay; Sensitivity and Specificity; Spinal Dysraphism | 1998 |
[Epidemiology of prenatal diagnosis and selective pregnancy termination because of fetal neural tube defects in The Netherlands in comparison to other European countries].
Topics: Abortion, Therapeutic; Anencephaly; Epidemiologic Methods; Europe; Female; Folic Acid; Humans; Infant, Newborn; Netherlands; Neural Tube Defects; Pregnancy; Prenatal Diagnosis; Prevalence; Retrospective Studies; Spinal Dysraphism | 1997 |
Maternal vitamin use, genetic variation of infant methylenetetrahydrofolate reductase, and risk for spina bifida.
Topics: Case-Control Studies; Dietary Supplements; Female; Folic Acid; Genotype; Humans; Infant, Newborn; Methylenetetrahydrofolate Dehydrogenase (NADP); Odds Ratio; Point Mutation; Pregnancy; Risk; Spinal Dysraphism; Vitamins | 1998 |
Evaluation of the MTHFR C677T allele and the MTHFR gene locus in a German spina bifida population.
Topics: Alleles; Case-Control Studies; Family; Female; Folic Acid; Genetic Linkage; Germany; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Spinal Dysraphism | 1998 |
How does folic acid prevent neural tube defects?
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Animals; Disease Models, Animal; Embryonic and Fetal Development; Female; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Oxidoreductases; Pregnancy; Spinal Dysraphism | 1998 |
A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity.
Topics: Adult; Black People; Child; Female; Folic Acid; Gene Frequency; Genetic Variation; Homocysteine; Homocystinuria; Homozygote; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Protein Denaturation; Spinal Dysraphism | 1998 |
Spina bifida.
Topics: Australia; Female; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Patient Education as Topic; Pregnancy; Spinal Dysraphism | 1998 |
Impaired regeneration of monoglutamyl tetrahydrofolate leads to cellular folate depletion in mothers affected by a spina bifida pregnancy.
Topics: Female; Folic Acid; Folic Acid Deficiency; Humans; Pregnancy; Pregnancy Complications; Spinal Dysraphism; Tetrahydrofolates; Vitamin B 12 | 1998 |
Infant methionine synthase variants and risk for spina bifida.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Folic Acid; Genotype; Humans; Infant, Newborn; Polymorphism, Genetic; Risk; Spinal Dysraphism | 1999 |
Spina bifida and folate.
Topics: Australia; Female; Folic Acid; Health Education; Health Knowledge, Attitudes, Practice; Humans; Pregnancy; Spinal Dysraphism | 1999 |
Spina bifida and folate.
Topics: Australia; Dietary Supplements; Female; Folic Acid; Food Labeling; Humans; New Zealand; Pregnancy; Spinal Dysraphism | 1999 |
Tapping the savings from vitamin-based prevention.
Topics: Coronary Disease; Cost Savings; Cost-Benefit Analysis; Female; Folic Acid; Heart Defects, Congenital; Hospitalization; Humans; Infant, Low Birth Weight; Infant, Newborn; Managed Care Programs; Outcome Assessment, Health Care; Pregnancy; Pregnancy Outcome; Prenatal Care; Spinal Dysraphism; United States; Vitamins; Zinc | 1998 |
[Folic acid supplementation by 200 microgram per day during the periconceptional period: a necessary public health approach to reducing incidence of spina bifida].
Topics: Dietary Supplements; Female; Folic Acid; France; Humans; Pregnancy; Pregnancy Complications; Public Health; Spinal Dysraphism | 1999 |
[Primary prevention of developmental abnormalities].
Topics: Abortion, Induced; Anencephaly; Congenital Abnormalities; Female; Folic Acid; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Pyridoxine; Spinal Dysraphism; Ultrasonography, Prenatal; Vitamin B 12 | 1999 |
Folate status and neural tube defects.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Dietary Supplements; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Genetic Variation; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects; Oxidoreductases; Point Mutation; Pregnancy; Pregnancy Complications; Spinal Dysraphism | 1999 |
[Periconceptual folic acid intake by Sicilian couples at a risk of recurrence of NTD].
Topics: Adult; Anencephaly; Female; Fertilization; Folic Acid; Humans; Interviews as Topic; Italy; Male; Neural Tube Defects; Pregnancy; Risk Factors; Spinal Dysraphism | 1999 |
Altered folate metabolism and disposition in mothers affected by a spina bifida pregnancy: influence of 677c --> t methylenetetrahydrofolate reductase and 2756a --> g methionine synthase genotypes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Chromatography, High Pressure Liquid; Female; Folic Acid; Gene Frequency; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Pteroylpolyglutamic Acids; Spinal Dysraphism; Substrate Specificity | 2000 |
Folic acid researchers honoured.
Topics: Awards and Prizes; Bread; Female; Folic Acid; Food, Fortified; Humans; Pregnancy; Spinal Dysraphism; United Kingdom | 2000 |
The unnecessary epidemic of folic acid-preventable spina bifida and anencephaly.
Topics: Anencephaly; Female; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Neural Tube Defects; Population Surveillance; Pregnancy; Prevalence; South Carolina; Spinal Dysraphism | 2000 |
Inadequate folic acid intakes are prevalent among young women with neural tube defects.
Topics: Adolescent; Adult; Baltimore; Delaware; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Nutritional Requirements; Prevalence; Risk Factors; Spinal Dysraphism | 2001 |
A screen for mutations in human homologues of mice exencephaly genes Tfap2alpha and Msx2 in patients with neural tube defects.
Topics: Alleles; Anencephaly; Animals; Base Sequence; Carrier Proteins; Codon; DNA-Binding Proteins; DNA, Complementary; Encephalocele; Exons; Folate Receptors, GPI-Anchored; Folic Acid; Gene Deletion; Genotype; Homeodomain Proteins; Humans; Mice; Molecular Sequence Data; Mutation; Neural Tube Defects; Pedigree; Point Mutation; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Receptors, Cell Surface; Spinal Dysraphism; Transcription Factor AP-2; Transcription Factors | 2001 |
JAMA patient page. Spina bifida.
Topics: Dietary Supplements; Female; Folic Acid; Humans; Neural Tube Defects; Pregnancy; Spinal Dysraphism | 2001 |
[Vascular diseases, spina bifida and schizophrenia in a single family associated with the heterozygote mutation of the heat-sensitive variant of methylenetetrahydrofolate reductase].
Topics: Adult; Female; Folic Acid; Heterozygote; Hot Temperature; Humans; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pedigree; Pulmonary Embolism; Schizophrenia; Spinal Dysraphism; Thrombosis; Vascular Diseases | 2001 |
An examination of polymorphic genes and folate metabolism in mothers affected by a spina bifida pregnancy.
Topics: Adult; Alleles; England; Erythrocytes; Female; Folic Acid; Gene Frequency; Humans; Methionine; Methylation; Mutation; Polyglutamic Acid; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Pregnancy; Pteroylpolyglutamic Acids; Spinal Dysraphism; Vitamin B 12 | 2001 |
Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida.
Topics: Amino Acid Substitution; Biological Transport; Carrier Proteins; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Infant, Newborn; Membrane Proteins; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Single Nucleotide; Pregnancy; Spinal Dysraphism | 2002 |
In praise of folic acid.
Topics: Alzheimer Disease; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Male; Spinal Dysraphism; United States | 2002 |
Cost-effectiveness of periconceptional supplementation of folic acid.
Topics: Cost of Illness; Cost-Benefit Analysis; Dietary Supplements; Female; Folic Acid; Humans; Neural Tube Defects; Pregnancy; Spinal Dysraphism | 2002 |
Trends in neural tube defects in Western Australia.
Topics: Anencephaly; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Spinal Dysraphism; Western Australia | 2002 |
Outcomes in pregnancy.
Topics: Animals; Female; Fetal Death; Folic Acid; Folic Acid Deficiency; Humans; Macaca mulatta; Pregnancy; Pregnancy Outcome; Spinal Dysraphism | 2002 |
Folates and the fetus.
Topics: Central Nervous System; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pregnancy Trimester, Second; Spinal Dysraphism | 1977 |
Folates and fetal central-nervous-system malformations.
Topics: Anencephaly; Female; Folic Acid; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Pregnancy; Spinal Dysraphism | 1977 |
From the Centers for Disease Control. Use of folic acid for prevention of spina bifida and other neural tube defects--1983-1991.
Topics: Anencephaly; Encephalocele; Female; Folic Acid; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Pregnancy Outcome; Spinal Dysraphism | 1991 |
Pathogenesis of spina bifida.
Topics: Anencephaly; Biological Assay; Female; Folic Acid; Folic Acid Deficiency; Humans; Karyotyping; Lactobacillus; Male; Parents; Pregnancy; Spinal Dysraphism | 1969 |
Effects of deficiencies in labile methyl groups on the growth and development of fetal rats.
Topics: Animals; Choline; Congenital Abnormalities; Deficiency Diseases; Diet; Embryonic and Fetal Development; Estrus; Female; Fertility; Fetal Death; Folic Acid; Formaldehyde; Glycine; Growth; Hernia, Umbilical; Hydrocephalus; Kidney Cortex Necrosis; Male; Niacinamide; Nutritional Requirements; Oxidation-Reduction; Pregnancy; Rats; Reproduction; Sarcosine; Spinal Dysraphism; Vitamin B 12 | 1970 |