Page last updated: 2024-08-17

folic acid and Choline Deficiency

folic acid has been researched along with Choline Deficiency in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (29.41)	18.7374
1990's	9 (17.65)	18.2507
2000's	9 (17.65)	29.6817
2010's	18 (35.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cherrington, NJ; Hardwick, RN; Lake, AD; Leamon, CP; Low, PS	1
Beland, FA; de Conti, A; James, SJ; Kutanzi, K; Latendresse, JR; Melnyk, S; Montgomery, B; Muskhelishvili, L; Pogribna, M; Pogribny, IP; Rusyn, I; Tryndyak, V	1
MacFarlane, AJ; McEntee, MF; Stover, PJ	1
Ishii, D; Kawai, K; Mashimo, Y; Matsuda, S; Matsuzawa, D; Shimizu, E; Sutoh, C; Tomizawa, H	1
Hollenbeck, CB	1
Blusztajn, JK; Crivello, NA; Joseph, JA; Shukitt-Hale, B; Smith, DE	1
Alberto, JM; Bossenmeyer-Pourie, C; Bressenot, A; Chen, M; Coste, F; George, A; Guéant, JL; Namour, B; Peyrin-Biroulet, L; Xia, B	1
Abarinov, EV; Allen, RH; Beaudin, AE; Chu, S; Noden, DM; Perry, CA; Stabler, SP; Stover, PJ	1
Abarinov, EV; Beaudin, AE; Caudill, M; Malysheva, O; Perry, CA; Stover, PJ	1
Shane, B	1
Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M	1
Allen, RH; Beaudin, AE; Perry, CA; Stabler, SP; Stover, PJ	1
Fenech, M; Lu, L; Ni, J; Wang, X; Xu, W; Zhou, T	1
Bressenot, A; Bronowicki, JP; Chango, A; Forges, T; Guéant, JL; Namour, F; Pellanda, H	1
Liu, Y; Liu, YQ; Morita, T; Sugiyama, K	1
Bossenmeyer-Pourie, C; Bressenot, A; Chevaux, JB; Coste, F; Gauchotte, G; Germain, A; Guéant, JL; Peyrin-Biroulet, L; Pooya, S; Vignaud, JM	1
Beland, FA; Collins, L; de Conti, A; Fuscoe, JC; Han, T; Kobets, T; Koturbash, I; Kutanzi, K; Latendresse, JR; Melnyk, S; Pogribny, IP; Ross, SA; Rusyn, I; Shymonyak, S; Tryndyak, V	1
Liu, Y; Liu, YQ; Mori, M; Morita, T; Sugiyama, K	1
FRITZ, IB	1
DUPONT, P; FRITZ, IB	1
DALAL, FR; FATTERPAKER, P; REGE, DV; SREENIVASAN, A	1
COPELAND, DH; HALE, OM; SALMON, WD; SCHAEFER, AE	1
Davis, CD; Uthus, EO	1
da Costa, KA; Fischer, LM; Kohlmeier, M; Zeisel, SH	1
Craciunescu, CN; da Costa, KA; Fischer, LM; Niculescu, MD; Zeisel, SH	1
Benjamin, J; Gossell-Williams, M	1
Allen, RH; daCosta, KA; Fischer, LM; Kwock, L; Lu, TS; Stabler, SP; Stewart, PW; Zeisel, SH	1
Zeisel, SH	1
Alberto, JM; Audonnet-Blaise, S; Blaise, SA; Daval, JL; Guéant, JL	1
Hegsted, DM; McCombs, HL; Roach, AM	1
Nauss, KM; Newberne, PM	1
Henning, SM; Jacob, RA; Pianalto, FS; Swendseid, ME; Zhang, JZ	1
Baik, MG; Choi, CB; Keller, WL; Park, CS	1
Pérez de Miguelsanz, J; Ragel, C; Varela-Moreiras, G	1
Alonso-Aperte, E; Varela-Moreiras, G	1
Henning, SM; Swendseid, ME	1
Albright, CD; Citarella, MT; da Costa, KA; Mar, MH; Shin, OH; Zeisel, SH	1
Le Leu, RK; McIntosh, GH; Young, GP	1
Brand, GM; Duthie, SJ; Grant, G; Narayanan, S	1
Duthie, SJ; Grant, G; Narayanan, S	1
Cornwell, PE; Krumdieck, CL; Leichter, J; Thompson, RW	1
Cross, DR; James, SJ; Miller, BJ	1
Pomfret, EA; Selhub, J; Seyoum, E; Zeisel, SH	1
Newberne, PM; Rogers, AE	1
James, SJ; Yin, L	1
Cook, RJ; Horne, DW; Wagner, C	1
Blair, R; Newsome, F	1
Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ	1
Fuller, HL; Keshavarz, K	1
Jensen, LS; Latshaw, JD	1

Reviews

6 review(s) available for folic acid and Choline Deficiency

Article	Year
DNA methylation, cancer susceptibility, and nutrient interactions. Experimental biology and medicine (Maywood, N.J.), 2004, Volume: 229, Issue:10 Topics: Animals; Choline Deficiency; Deficiency Diseases; Diet; Disease Susceptibility; DNA Methylation; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Neoplasms; Selenium	2004
Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline. IUBMB life, 2007, Volume: 59, Issue:6 Topics: Animals; Brain; Choline; Choline Deficiency; Diet; Epigenesis, Genetic; Estrogens; Folic Acid; Humans; Methionine; Nutritional Requirements; Polymorphism, Genetic; Response Elements; Vitamin B Complex	2007
Effects of dietary folate, vitamin B12 and methionine/choline deficiency on immune function. Advances in experimental medicine and biology, 1981, Volume: 135 Topics: Animals; Antibody Formation; Choline Deficiency; Deoxyuridine; Drug Interactions; Folic Acid; Folic Acid Deficiency; Humans; Hypersensitivity, Delayed; Immunity; Lymphocyte Activation; Lymphocytes; Lymphoid Tissue; Methionine; Vitamin B 12; Vitamin B 12 Deficiency	1981
The role of folate, choline, and methionine in carcinogenesis induced by methyl-deficient diets. Advances in experimental medicine and biology, 1996, Volume: 399 Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Humans; Liver Neoplasms; Methionine; Neoplasms	1996
Labile methyl groups and the promotion of cancer. Annual review of nutrition, 1986, Volume: 6 Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency	1986
Involvement of water-soluble vitamins in diseases of swine. Journal of animal science, 1985, Volume: 60, Issue:6 Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Biotin; Choline; Choline Deficiency; Folic Acid; Folic Acid Deficiency; Niacin; Nutritional Requirements; Pantothenic Acid; Pyridoxine; Riboflavin; Riboflavin Deficiency; Solubility; Swine; Swine Diseases; Thiamine; Thiamine Deficiency; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamins; Water	1985

Trials

4 trial(s) available for folic acid and Choline Deficiency

Article	Year
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women. The British journal of nutrition, 2012, Volume: 108, Issue:7 Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipids; Middle Aged; Northern Ireland; Nutritional Status; Patient Compliance; Postmenopause	2012
Choline deficiency increases lymphocyte apoptosis and DNA damage in humans. The American journal of clinical nutrition, 2006, Volume: 84, Issue:1 Topics: Adolescent; Adult; Aged; Apoptosis; Biomarkers; Caspase 3; Caspases; Choline; Choline Deficiency; Comet Assay; DNA Damage; Female; Folic Acid; Humans; In Situ Nick-End Labeling; Liver; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Muscle, Skeletal	2006
Sex and menopausal status influence human dietary requirements for the nutrient choline. The American journal of clinical nutrition, 2007, Volume: 85, Issue:5 Topics: Adolescent; Adult; Aged; Choline; Choline Deficiency; Dose-Response Relationship, Drug; Fatty Liver; Female; Folic Acid; Humans; Male; Menopause; Middle Aged; Muscle, Skeletal; Nutrition Policy; Nutritional Requirements; Phosphatidylcholines; Sex Factors	2007
In vivo methylation capacity is not impaired in healthy men during short-term dietary folate and methyl group restriction. The Journal of nutrition, 1995, Volume: 125, Issue:6 Topics: Administration, Oral; Adult; Carnitine; Choline; Choline Deficiency; Creatinine; Cross-Over Studies; Diet; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Male; Methionine; Methylation; Middle Aged; Niacinamide; Time Factors	1995

Other Studies

41 other study(ies) available for folic acid and Choline Deficiency

Article	Year
Folate receptor-beta expression as a diagnostic target in human & rodent nonalcoholic steatohepatitis. Toxicology and applied pharmacology, 2019, 04-01, Volume: 368 Topics: Animals; Biomarkers; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Folate Receptor 2; Folic Acid; Humans; Liver; Macrophages; Male; Methionine; Mice, Inbred C57BL; Molecular Imaging; Non-alcoholic Fatty Liver Disease; Organotechnetium Compounds; Predictive Value of Tests; Radiopharmaceuticals; Rats, Sprague-Dawley; Tomography, Emission-Computed, Single-Photon	2019
Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:6 Topics: Animals; Carbon; Choline; Choline Deficiency; Cystathionine beta-Synthase; Disease Models, Animal; Down-Regulation; Fatty Liver; Folic Acid; Folic Acid Deficiency; Humans; Liver; Male; Methionine Adenosyltransferase; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred Strains; Non-alcoholic Fatty Liver Disease; Species Specificity	2013
Azoxymethane-induced colon carcinogenesis in mice occurs independently of de novo thymidylate synthesis capacity. The Journal of nutrition, 2014, Volume: 144, Issue:4 Topics: Animals; Azoxymethane; Carcinogenesis; Choline Deficiency; Colon; Colonic Neoplasms; Crosses, Genetic; Disease Models, Animal; DNA; Extracellular Matrix Proteins; Folic Acid; Folic Acid Deficiency; Glycine Hydroxymethyltransferase; Male; Mice; Mice, Knockout; Mice, Transgenic; Neoplasm Proteins; Protein-Lysine 6-Oxidase; Random Allocation; Thymidine Monophosphate; Tumor Burden; Uracil	2014
Methyl-donor deficiency in adolescence affects memory and epigenetic status in the mouse hippocampus. Genes, brain, and behavior, 2015, Volume: 14, Issue:3 Topics: Age Factors; Animals; Choline; Choline Deficiency; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Hippocampus; Homocysteine; Memory; Methionine; Mice; Mice, Inbred C57BL; Models, Animal; Nutritional Requirements; Promoter Regions, Genetic; Receptors, AMPA; Receptors, Glutamate	2015
The importance of being choline. Journal of the American Dietetic Association, 2010, Volume: 110, Issue:8 Topics: Brain; Choline; Choline Deficiency; Folic Acid; Humans; Lipotropic Agents; Liver; Methionine; Nootropic Agents; Nutrition Policy; Nutritional Requirements	2010
Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age. Nutrition research (New York, N.Y.), 2010, Volume: 30, Issue:10 Topics: Acetylcholine; Aging; Animals; Brain; Choline; Choline Deficiency; Diet; Dopamine; Folic Acid; Folic Acid Deficiency; Kidney; Liver; Lung; Male; Myocardium; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Vitamin B Complex	2010
Methyl deficient diet aggravates experimental colitis in rats. Journal of cellular and molecular medicine, 2011, Volume: 15, Issue:11 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Choline Deficiency; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Dextran Sulfate; Diet; Folic Acid; Folic Acid Deficiency; Glutathione Peroxidase; Homocysteine; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A2; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-3; Tumor Necrosis Factor-alpha; Vitamin B 12; Vitamin B 12 Deficiency	2011
Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice. The American journal of clinical nutrition, 2011, Volume: 93, Issue:4 Topics: Animals; Biomarkers; Choline; Choline Deficiency; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Gene Expression; Glycine Hydroxymethyltransferase; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neural Tube Defects; Purines; Severity of Illness Index; Thymidine Monophosphate; Thymidylate Synthase; Vitamin B Complex	2011
Dietary folate, but not choline, modifies neural tube defect risk in Shmt1 knockout mice. The American journal of clinical nutrition, 2012, Volume: 95, Issue:1 Topics: Animals; Choline; Choline Deficiency; Diet; Disease Models, Animal; Energy Intake; Folic Acid; Folic Acid Deficiency; Glycine Hydroxymethyltransferase; Mice; Mice, Knockout; Neural Tube Defects; Risk Factors	2012
Folate-responsive birth defects: of mice and women. The American journal of clinical nutrition, 2012, Volume: 95, Issue:1 Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Glycine Hydroxymethyltransferase; Mutation; Neural Tube Defects; Thymidine Monophosphate; Vitamin B Complex	2012
Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. The American journal of clinical nutrition, 2012, Volume: 95, Issue:4 Topics: Aminohydrolases; Animals; Choline; Choline Deficiency; Crosses, Genetic; Disease Models, Animal; Embryo Loss; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Formate-Tetrahydrofolate Ligase; Genes, Lethal; Heterozygote; Homocysteine; Hypoxanthine; Maternal Nutritional Physiological Phenomena; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Mutant Strains; Multienzyme Complexes; Mutagenesis, Insertional; Neural Tube Defects; Pregnancy	2012
Choline and/or folic acid deficiency is associated with genomic damage and cell death in human lymphocytes in vitro. Nutrition and cancer, 2012, Volume: 64, Issue:3 Topics: Adult; Apoptosis; Cell Death; Cell Nucleus; Cells, Cultured; Choline; Choline Deficiency; DNA Damage; Female; Folic Acid; Folic Acid Deficiency; Genomic Instability; Humans; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Necrosis	2012
Fumonisin FB1 treatment acts synergistically with methyl donor deficiency during rat pregnancy to produce alterations of H3- and H4-histone methylation patterns in fetuses. Molecular nutrition & food research, 2012, Volume: 56, Issue:6 Topics: Abnormalities, Drug-Induced; Animals; Choline Deficiency; Fatty Liver; Female; Folic Acid; Folic Acid Deficiency; Folic Acid Transporters; Fumonisins; Gene Expression Regulation, Developmental; Heterochromatin; Histones; Liver; Maternal Nutritional Physiological Phenomena; Methylation; Neural Tube Defects; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; Teratogens; Vitamin B 12 Deficiency	2012
Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats. Journal of nutritional science and vitaminology, 2012, Volume: 58, Issue:2 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline Deficiency; Dietary Supplements; Enzyme Inhibitors; Folic Acid; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Wistar; Sarcosine	2012
Methyl donor deficiency affects small-intestinal differentiation and barrier function in rats. The British journal of nutrition, 2013, Feb-28, Volume: 109, Issue:4 Topics: Alkaline Phosphatase; Animal Feed; Animals; Apoptosis; beta Catenin; Cadherins; Caspase 3; Cell Differentiation; Choline; Choline Deficiency; Enterocytes; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Intestine, Small; Muramidase; Paneth Cells; Rats; Rats, Wistar; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency	2013
Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:11 Topics: Animal Feed; Animals; Choline; Choline Deficiency; Cytochrome P-450 Enzyme System; Diet; DNA Damage; Fatty Liver; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Genetic Variation; Lipid Metabolism; Male; Mice; Mice, Inbred Strains; Oxidative Stress; Protein Array Analysis; Transcriptome	2012
Effect of dietary supplementation with folate on choline deficiency-induced hyperhomocysteinemia in rats. Journal of nutritional science and vitaminology, 2012, Volume: 58, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Choline Deficiency; Cystathionine beta-Synthase; Dietary Supplements; Folic Acid; Hyperhomocysteinemia; Liver; Male; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Serine; Tetrahydrofolates	2012
Effects of choline deficiency and carnitine on palmitic acid oxidation by rat liver homogenates. The American journal of physiology, 1957, Volume: 190, Issue:3 Topics: Animals; Carnitine; Choline; Choline Deficiency; Fatty Acids; Folic Acid; Lipid Metabolism; Liver; Oxidation-Reduction; Palmitic Acid; Rats; Ventricular Fibrillation; Vitamin B Complex	1957
Ineffectiveness of carnitine as a choline substitute in the prevention of fatty livers of rats maintained on a choline-deficient diet. The American journal of physiology, 1957, Volume: 190, Issue:3 Topics: Animals; Carnitine; Choline; Choline Deficiency; Diet; Fatty Liver; Folic Acid; Rats; Vitamin B Complex	1957
Effect of dietary deficiencies of folic acid and choline on lipid metabolism in the rat. The Indian journal of medical research, 1960, Volume: 48 Topics: Animals; Choline; Choline Deficiency; Folic Acid; Folic Acid Deficiency; Lipid Metabolism; Lipids; Rats	1960
The influence of riboflavin, pyridoxine, inositol, and protein depletion- repletion upon the induction of neoplasms by choline deficiency. Cancer research, 1950, Volume: 10, Issue:12 Topics: Choline Deficiency; Folic Acid; Humans; Inositol; Neoplasms; Pyridoxine; Riboflavin; Vitamin B Complex	1950
Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proceedings of the National Academy of Sciences of the United States of America, 2005, Nov-01, Volume: 102, Issue:44 Topics: Adult; Aged; Carbon; Choline; Choline Deficiency; Female; Folic Acid; Genetic Predisposition to Disease; Heterozygote; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Polymorphism, Genetic; Premenopause	2005
Choline: are our university students eating enough? The West Indian medical journal, 2006, Volume: 55, Issue:3 Topics: Adult; Betaine; Choline Deficiency; Female; Folic Acid; Food Analysis; Humans; Jamaica; Male; Nutrition Assessment; Nutritional Status; Pilot Projects; Students, Medical; Universities	2006
Influence of preconditioning-like hypoxia on the liver of developing methyl-deficient rats. American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:6 Topics: Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Choline Deficiency; Cystathionine beta-Synthase; Female; Folic Acid; Folic Acid Deficiency; Food, Formulated; Glutathione; Homocysteine; Hypoxia; Liver; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Wistar; Riboflavin; Riboflavin Deficiency; S-Adenosylhomocysteine; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Deficiency	2007
Effect of vitamin B-12 in choline deficiency in the rat. The Journal of nutrition, 1967, Volume: 92, Issue:3 Topics: Amino Acids; Animals; Body Weight; Choline; Choline Deficiency; Diet; FIGLU Test; Folic Acid; Growth; Hematocrit; Hemoglobins; Kidney; Lipid Metabolism; Liver; Male; Methionine; Organ Size; Rats; Vitamin B 12; Vitamin B Deficiency	1967
Modulation of expression of fos and Ha-ras oncogenes and ornithine decarboxylase activity in mammary gland and liver of young female rats by the absence of dietary lipotropes. Journal of dairy science, 1994, Volume: 77, Issue:8 Topics: Animals; Choline; Choline Deficiency; Diet; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Genes, fos; Genes, ras; Liver; Mammary Glands, Animal; Methionine; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Vitamin B 12 Deficiency	1994
Choline deficiency and methotrexate treatment induces marked but reversible changes in hepatic folate concentrations, serum homocysteine and DNA methylation rates in rats. Journal of the American College of Nutrition, 1995, Volume: 14, Issue:5 Topics: Animals; Choline; Choline Deficiency; DNA Modification Methylases; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Male; Methotrexate; Methylation; Rats; Rats, Wistar	1995
Brain folates and DNA methylation in rats fed a choline deficient diet or treated with low doses of methotrexate. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1996, Volume: 66, Issue:3 Topics: Animals; Brain; Choline; Choline Deficiency; Diet; DNA Methylation; Folic Acid; Male; Methotrexate; Rats; Rats, Wistar	1996
Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency. Journal of cellular biochemistry, 1997, Volume: 64, Issue:2 Topics: Animals; Apoptosis; Betaine; Cell Line; Choline Deficiency; Culture Media; Folic Acid; Liver; Male; Methylation; Rats; Rats, Inbred F344; Vitamin B 12	1997
Ability of endogenous folate from soy protein isolate to maintain plasma homocysteine and hepatic DNA methylation during methyl group depletion in rats. Journal of nutritional science and vitaminology, 1998, Volume: 44, Issue:3 Topics: 5-Methylcytosine; Animals; Caseins; Choline Deficiency; Cytosine; Dietary Proteins; DNA; DNA Methylation; Folic Acid; Folic Acid Deficiency; Homocysteine; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; Soybean Proteins; Weaning	1998
DNA stability and genomic methylation status in colonocytes isolated from methyl-donor-deficient rats. European journal of nutrition, 2000, Volume: 39, Issue:3 Topics: Animals; Choline Deficiency; Colon; Colonic Neoplasms; Comet Assay; DNA; DNA Damage; DNA Methylation; Folic Acid; Folic Acid Deficiency; Liver; Male; Methionine; Rats; S-Adenosylmethionine; Vitamin B 12	2000
Increased uracil misincorporation in lymphocytes from folate-deficient rats. British journal of cancer, 2000, Volume: 83, Issue:11 Topics: Animals; Choline Deficiency; Comet Assay; DNA; DNA Damage; Erythrocytes; Folic Acid; Folic Acid Deficiency; Liver; Lymphocytes; Male; Methionine; Rats; Uracil; Vitamin B 12	2000
Alterations in the chain length of pteroylpoly-gamma-glutamates and in the activity of pteroylpoly-gamma-glutamate hydrolase in response to changes in the steady state of one carbon metabolism. The American journal of clinical nutrition, 1977, Volume: 30, Issue:10 Topics: Animals; Carboxypeptidases; Caseins; Choline Deficiency; Coturnix; Dietary Proteins; Folic Acid; gamma-Glutamyl Hydrolase; Glutamates; Liver; Male; Methionine; Quail	1977
Alterations in nucleotide pools in rats fed diets deficient in choline, methionine and/or folic acid. Carcinogenesis, 1992, Volume: 13, Issue:12 Topics: Animals; Choline; Choline Deficiency; Chromatography, High Pressure Liquid; Diet; Folic Acid; Folic Acid Deficiency; Male; Methionine; Nucleotides; Rats; Rats, Inbred F344; Spleen	1992
Effects of choline deficiency and methotrexate treatment upon liver folate content and distribution. Cancer research, 1991, Jan-01, Volume: 51, Issue:1 Topics: Animals; Choline Deficiency; Chromatography, High Pressure Liquid; Folic Acid; Liver; Methotrexate; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains; Tetrahydrofolates	1991
Diet-induced DNA damage and altered nucleotide metabolism in lymphocytes from methyl-donor-deficient rats. Carcinogenesis, 1989, Volume: 10, Issue:7 Topics: Animals; Choline; Choline Deficiency; Deoxyuridine; Diet; DNA Damage; DNA Replication; Folic Acid; Folic Acid Deficiency; Liver; Lymphocytes; Male; Methionine; NAD; Nucleotides; Rats; Rats, Inbred F344; Reference Values; RNA; Spleen; Thymidine	1989
Methyl group deficiency: effects on one-carbon unit and folate metabolism. Nutrition reviews, 1989, Volume: 47, Issue:12 Topics: Animals; Choline Deficiency; Folic Acid; Glycine N-Methyltransferase; Methionine; Methylation; Methyltransferases; Oxidation-Reduction; Rats	1989
Effect of dietary methyl group deficiency on folate metabolism in rats. The Journal of nutrition, 1989, Volume: 119, Issue:4 Topics: Amino Acids; Animals; Choline Deficiency; Chromatography, High Pressure Liquid; Diet; Folic Acid; Leucovorin; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred F344; Tetrahydrofolates	1989
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma. Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 27, Issue:2 Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency	1972
Relationship of arginine and methionine to creatine formation in chicks. The Journal of nutrition, 1971, Volume: 101, Issue:7 Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Chickens; Choline; Choline Deficiency; Creatine; Cystine; Deficiency Diseases; Depression, Chemical; Folic Acid; Folic Acid Deficiency; Glycine; Glycine max; Guanidines; Lipid Metabolism; Liver; Male; Methionine; Muscles; Ornithine; Stimulation, Chemical; Urea; Vitamin B 12; Vitamin B 12 Deficiency; Zea mays	1971
Choline level and its effect on egg weight in the Japanese quail. Poultry science, 1971, Volume: 50, Issue:3 Topics: Animal Nutritional Physiological Phenomena; Animals; Biotin; Bird Diseases; Birds; Choline Deficiency; Eggs; Female; Folic Acid; Inositol; Methionine; Nutritional Requirements; Ovulation; Vitamin B 12	1971