folic acid has been researched along with Cell Transformation, Neoplastic in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (19.30) | 18.7374 |
| 1990's | 2 (3.51) | 18.2507 |
| 2000's | 20 (35.09) | 29.6817 |
| 2010's | 21 (36.84) | 24.3611 |
| 2020's | 3 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Lei, QY; Li, J; Liu, S; Su, Y; Wang, D; Yin, M; Zhang, F | 1 |
| Bayer, M; Boller, S; Edwards-Hicks, J; Grosschedl, R; Grün, D; Herman, JS; Klein-Geltink, R; Kometani, K; Li, R; Pearce, EL; Ramachandran, H; Ramamoorthy, S | 1 |
| Arai, T; Chijimatsu, R; Doki, Y; Eguchi, H; Hirotsu, T; Ishii, H; Kitagawa, T; Ofusa, K; Takeda, Y; Vecchione, A; Yabumoto, M | 1 |
| Bhattacharjee, P; Giri, AK; Paul, S | 1 |
| Ehlers, A; Lampen, A; Mai, HD; Nemitz, A; Niemann, B; Steinberg, P; Werner, J | 1 |
| Ao, M; Cao, Y; Hao, L; Hu, Z; Huang, J; Li, A; Li, P; Liu, J; Liu, Y; Ran, H; Wang, Z; Xu, F; Xu, J; Yao, Y | 1 |
| Asante, I; Chui, D; Conti, D; De Giovanni, C; Louie, S; Pei, H; Zhou, E | 1 |
| Kim, DW; Kim, MH; Kim, SG | 1 |
| Bozbey, HU; Erturk, K; Kiziltan, H; Olmuscelik, O; Tas, F; Tastekin, D; Tuna, S | 1 |
| Aranda-Lara, L; Díaz-Nieto, L; Ferro-Flores, G; Isaac-Olivé, K; Ocampo-García, B; Ramírez, Fde M; Santos-Cuevas, C | 1 |
| Chen, X; Ding, L; Li, J; Liu, XZ; Nan, J; Wang, JT; Wu, TT | 1 |
| Empl, MT; Gerhard, D; Hausmann, J; Nicken, P; Steinberg, P | 1 |
| Kim, YI | 1 |
| Ulrich, CM | 1 |
| Chen, YX; Fang, JY; Lu, R; Sun, DF; Tian, XQ; Wang, X; Zhao, SL | 1 |
| Chen, ZG; Cho, KJ; Giannakakou, P; Gjyrezi, A; Kim, G; Koenig, L; Li, J; Nie, S; Shin, DM; Shin, HJ; Tighiouart, M; Wang, X; Wang, Y | 1 |
| Alazzam, M; Hancock, BW; Powers, H; Tidy, J | 1 |
| Holt, PR; Hopkins, ME; Kim, M; Kleinstein, SH; Kopelovich, L; Laird, PW; Lambrecht, RW; Lipkin, M; Liu, Z; Marshall, JR; Mason, JB; Nelson, C; Pendyala, S; Protiva, P | 1 |
| Hür, D; Işcan, A; Kutlu, HM; Saltan, N; Say, R | 1 |
| Bassoli, BK; Chagas, CE; Dagli, ML; de Souza, CA; Deminice, R; Jordão Júnior, AA; Moreno, FS; Ong, TP; Paiva, SA | 1 |
| Al Jammaz, I; Al-Otaibi, B; Amer, S; Okarvi, SM | 1 |
| Carducci, MA; Herman, JG; Shabbeer, S; Simons, BW; Williams, SA | 1 |
| Campone, M; Cartron, PF; Debien, E; Hervouet, E; Loussouarn, D; Martin, SA; Menanteau, J; Olivier, C; Pouliquen, D; Vallette, FM | 1 |
| Ametamey, SM; Fischer, CR; Krämer, SD; Müller, A; Müller, C; Reber, J; Schibli, R | 1 |
| Cao, Y; Deng, L; Leclerc, D; Mikael, LG; Rozen, R; Wu, Q | 1 |
| Müller, C; Schibli, R; Struthers, H; Winiger, C; Zhernosekov, K | 1 |
| Krupenko, NI; Krupenko, SA; Strickland, KC | 1 |
| Ding, L; Hao, JX; Hao, M; Wang, JT; Zhao, WM; Zhou, Q | 1 |
| Choi, SW; Mason, JB | 2 |
| Moriarty, HT; Webster, LR | 1 |
| Bagnoli, M; Canevari, S; Ferri, R; Figini, M; Luison, E; Mezzanzanica, D; Miotti, S | 1 |
| Carrier, J; Choi, M; Hwang, SW; Kim, YI; Martin, R; Medline, A; Sohn, KJ | 1 |
| Fliessbach, K; Glasmacher, A; Heun, R; Klockgether, T; Kölsch, H; Linnebank, A; Linnebank, M; Pels, H; Schlegel, U; Schmidt, S; Schmidt-Wolf, IG | 1 |
| Bohnsack, BL; Hirschi, KK | 1 |
| Bosch, X; Castellsagué, X; García-Closas, R; González, CA | 1 |
| Azrad, M; Brill, I; Grizzle, WE; Jhala, D; Jhala, N; Kabagambe, EK; Macaluso, M; Niveleau, A; Piyathilake, CJ | 1 |
| Lim, U; Ziegler, RG | 1 |
| Powers, HJ | 1 |
| Mathers, JC; McKay, JA; Williams, EA | 1 |
| Azrad, M; Bell, WC; Celedonio, JE; Grizzle, WE; Macaluso, M; Piyathilake, CJ | 1 |
| Levesque, T; Mason, JB | 1 |
| Gunning, W; Ratnam, M; Wu, M | 1 |
| Freedman, AN; Ishibe, N | 1 |
| Duthie, SJ | 1 |
| Almadori, G; Bussu, F; Cadoni, G; Galli, J; Giardina, B; Minucci, A; Persichilli, S; Zappacosta, B | 1 |
| Erbe, RW; Hoffman, RM | 1 |
| Jacobsen, SJ; Mangum, JH; North, JA; Rao, NA | 1 |
| Neugut, AI; Weinstein, IB | 1 |
| Styles, JA | 1 |
| Conner, MW; Newberne, PM | 1 |
| Sirotnak, FM | 1 |
| Tempel, K | 1 |
| Balk, SD; Braun, AC; Whitfield, JF; Youdale, T | 1 |
| Friedkin, M | 1 |
| Balk, SD | 1 |
| Evans, VJ; Price, FM; Rotherham, J | 1 |
15 review(s) available for folic acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Impact of One-Carbon Metabolism-Driving Epitranscriptome as a Therapeutic Target for Gastrointestinal Cancer.
Topics: Animals; Carbon; Cell Transformation, Neoplastic; Folic Acid; Gastrointestinal Neoplasms; Humans; Methylation; Mitochondria; Reactive Oxygen Species; RNA | 2021 |
Arsenic toxicity and epimutagenecity: the new LINEage.
Topics: Arsenic; Arsenic Poisoning; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Environmental Exposure; Epigenesis, Genetic; Folic Acid; Genome, Human; Humans; Long Interspersed Nucleotide Elements; Neoplasms; Promoter Regions, Genetic; S-Adenosylmethionine | 2017 |
Folic acid supplementation and cancer risk: point.
Topics: Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Folic Acid; Humans; Neoplasm Recurrence, Local; Neoplasms; Primary Prevention | 2008 |
Folate and cancer prevention--where to next? Counterpoint.
Topics: Cell Transformation, Neoplastic; Colorectal Neoplasms; Folic Acid; Genetic Variation; Humans; Neoplasms; Prognosis | 2008 |
Gestational trophoblastic neoplasia, an ancient disease: new light and potential therapeutic targets.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Drug Delivery Systems; Epigenesis, Genetic; Female; Folic Acid; Gestational Trophoblastic Disease; Humans; Maternal Nutritional Physiological Phenomena; Medical Oncology; Models, Biological; Pregnancy | 2010 |
Molecular mechanisms underlying the potentially adverse effects of folate.
Topics: Cell Transformation, Neoplastic; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Humans; Male; Neoplasm Metastasis; Neoplasms; Neural Tube Defects; Prostatic Neoplasms; Tetrahydrofolate Dehydrogenase | 2013 |
Folate status: effects on pathways of colorectal carcinogenesis.
Topics: Cell Transformation, Neoplastic; Colorectal Neoplasms; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors | 2002 |
Fragile sites and bladder cancer.
Topics: Aphidicolin; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; Chromosome Breakage; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Distamycins; Folic Acid; Humans; Urinary Bladder Neoplasms | 2003 |
Nutrient regulation of cell cycle progression.
Topics: Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Diet; Disease Progression; Folic Acid; Glucose; Humans; Iron; Signal Transduction; Vitamin A; Vitamin B 12; Vitamin D; Zinc | 2004 |
The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence.
Topics: Carotenoids; Cell Transformation, Neoplastic; Cysteine; Diet; Female; Folic Acid; Homocysteine; Humans; Methionine; Nutritional Physiological Phenomena; Uterine Cervical Neoplasms; Vitamins | 2005 |
Folate: effects on carcinogenesis and the potential for cancer chemoprevention.
Topics: Animals; Cell Transformation, Neoplastic; Chemoprevention; Clinical Trials as Topic; Colorectal Neoplasms; Female; Folic Acid; Folic Acid Deficiency; Humans; Uterine Cervical Neoplasms | 1996 |
Folate and carcinogenesis: developing a unifying hypothesis.
Topics: Animals; Cell Transformation, Neoplastic; Folic Acid; Humans | 2000 |
Understanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis.
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p27; Dietary Fiber; Environmental Exposure; Enzyme Inhibitors; Folic Acid; Genes, APC; Genes, bcl-2; Genes, DCC; Genes, p53; Genes, ras; Genes, Tumor Suppressor; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Microtubule-Associated Proteins; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Smoking; Tumor Suppressor Proteins | 2001 |
Nutrient influences on toxicity and carcinogenicity.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Contraceptives, Oral; Diet; Dietary Fats; Dietary Proteins; Drug Interactions; Energy Intake; Folic Acid; Indoles; Pyridoxine; Toxins, Biological; Trace Elements; Vitamin A; Vitamins; Zinc | 1986 |
Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: biological significance and implications for improved therapy of human cancer.
Topics: Animals; Biological Transport; Cell Division; Cell Transformation, Neoplastic; Extraembryonic Membranes; Female; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Neoplasms; Oncogenes; Pregnancy | 1985 |
1 trial(s) available for folic acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Altered folate availability modifies the molecular environment of the human colorectum: implications for colorectal carcinogenesis.
Topics: Adult; Aged; Biological Availability; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; Dietary Supplements; DNA Breaks; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gene Expression; Gene Expression Profiling; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Rectum; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53 | 2011 |
41 other study(ies) available for folic acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Deacetylation of MTHFD2 by SIRT4 senses stress signal to inhibit cancer cell growth by remodeling folate metabolism.
Topics: Aminohydrolases; Cell Transformation, Neoplastic; Folic Acid; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondrial Proteins; Neoplasms; Sirtuins | 2022 |
EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism.
Topics: Animals; Carbon; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Folic Acid; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Interleukin-7; Mice; PAX5 Transcription Factor; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cells, B-Lymphoid; Protein Binding; Proto-Oncogene Proteins c-myc; Signal Transduction; Single-Cell Analysis; Trans-Activators | 2020 |
Folic acid modulates cancer-associated micro RNAs and inflammatory mediators in neoplastic and non-neoplastic colonic cells in a different way.
Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytokines; Dietary Supplements; DNA Methylation; Epithelial Cells; Folic Acid; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HT29 Cells; Humans; Inflammation Mediators; MicroRNAs; NF-kappa B; Promoter Regions, Genetic; Tumor Necrosis Factor-alpha | 2017 |
Low-intensity focused ultrasound (LIFU)-activated nanodroplets as a theranostic agent for noninvasive cancer molecular imaging and drug delivery.
Topics: Animals; Camptothecin; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Delivery Systems; Fluorocarbons; Folic Acid; Humans; Magnetite Nanoparticles; Mice; Mice, Nude; Molecular Imaging; Nanostructures; Theranostic Nanomedicine; Tissue Distribution; Ultrasonic Waves | 2018 |
Alterations in folate-dependent one-carbon metabolism as colon cell transition from normal to cancerous.
Topics: Caco-2 Cells; Carbon; Cell Proliferation; Cell Transformation, Neoplastic; Colon; DNA Methylation; Ferredoxin-NADP Reductase; Folate Receptor 1; Folic Acid; Gene Expression Regulation; Glycine Hydroxymethyltransferase; HCT116 Cells; Humans | 2019 |
A novel dual-modality imaging agent targeting folate receptor of tumor for molecular imaging and fluorescence-guided surgery.
Topics: Animals; Biological Transport; Cell Transformation, Neoplastic; Feasibility Studies; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Isotope Labeling; KB Cells; Mice; Optical Imaging; Organotechnetium Compounds; Peritoneal Neoplasms; Surgery, Computer-Assisted; Tissue Distribution | 2019 |
Plasma homocysteine, folate and vitamin B12 levels in patients with lung cancer.
Topics: Adult; Aged; Case-Control Studies; Cell Transformation, Neoplastic; Folic Acid; Homocysteine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Vitamin B 12 | 2015 |
Improved radiopharmaceutical based on 99mTc-Bombesin-folate for breast tumour imaging.
Topics: Animals; Bombesin; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Edetic Acid; Female; Folate Receptor 1; Folic Acid; Humans; Mice; Organotechnetium Compounds; Radiochemistry; Radiopharmaceuticals; Receptors, Bombesin; Tissue Distribution | 2016 |
[Interaction between folate and the expression of human papillomavirus 16 E6/E7 mRNA in the progression of cervix carcinogenesis].
Topics: Cell Transformation, Neoplastic; Disease Progression; Female; Folic Acid; Human papillomavirus 16; Humans; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Real-Time Polymerase Chain Reaction; Repressor Proteins; RNA, Messenger; Uterine Cervical Neoplasms | 2016 |
Methionine restriction inhibits chemically-induced malignant transformation in the BALB/c 3T3 cell transformation assay.
Topics: Animals; BALB 3T3 Cells; Cell Transformation, Neoplastic; Cells, Cultured; Colony-Forming Units Assay; Folic Acid; Methionine; Methylcholanthrene; Mice; Vitamin B Complex | 2016 |
Folic acid and sodium butyrate prevent tumorigenesis in a mouse model of colorectal cancer.
Topics: Acetylation; Animals; Body Weight; Butyrates; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Diet; Dietary Supplements; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Histones; Mice; Mice, Inbred ICR; Odds Ratio; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Transcription, Genetic | 2008 |
HFT-T, a targeting nanoparticle, enhances specific delivery of paclitaxel to folate receptor-positive tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Carrier Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Carriers; Female; Folate Receptors, GPI-Anchored; Folic Acid; Head and Neck Neoplasms; Heparin; Humans; Mice; Microtubules; Nanomedicine; Nanoparticles; Paclitaxel; Particle Size; Receptors, Cell Surface; Tissue Distribution | 2009 |
Interaction of cancer cells with magnetic nanoparticles modified by methacrylamido-folic acid.
Topics: Acrylamides; Animals; Antineoplastic Agents; Apoptosis; Cell Transformation, Neoplastic; Drug Delivery Systems; Ferrosoferric Oxide; Fibroblasts; Folic Acid; Genes, ras; Magnetite Nanoparticles; Mice; Microscopy, Electron, Transmission; NIH 3T3 Cells; Particle Size; Rats | 2011 |
Folic acid supplementation during early hepatocarcinogenesis: cellular and molecular effects.
Topics: Animals; Apoptosis; Body Weight; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Dietary Supplements; DNA Damage; DNA Methylation; Folic Acid; Gene Expression; Genes, myc; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine | 2011 |
Rapid synthesis and in vitro and in vivo evaluation of folic acid derivatives labeled with fluorine-18 for PET imaging of folate receptor-positive tumors.
Topics: Animals; Biological Transport; Cell Transformation, Neoplastic; Drug Stability; Female; Fluorine Radioisotopes; Folic Acid; Folic Acid Transporters; Humans; Hydrazines; KB Cells; Methotrexate; Mice; Mouth Neoplasms; Positron-Emission Tomography; Pyridines; Radiochemistry; Time Factors | 2011 |
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Choline; Decitabine; Diet; Disease Progression; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Methionine; Mice; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured; Vitamin B 6 | 2012 |
Folate supplementation limits the tumourigenesis in rodent models of gliomagenesis.
Topics: Animals; Cell Transformation, Neoplastic; Dietary Supplements; Disease Models, Animal; DNA Methylation; Folic Acid; Glioma; Humans; Mice; Survival Analysis; Xenograft Model Antitumor Assays | 2012 |
[18F]fluoro-deoxy-glucose folate: a novel PET radiotracer with improved in vivo properties for folate receptor targeting.
Topics: Alkynes; Animals; Cell Transformation, Neoplastic; Click Chemistry; Female; Folate Receptor 1; Folate Receptor 2; Folic Acid; Humans; Hydrophobic and Hydrophilic Interactions; KB Cells; Mice; Monosaccharides; Positron-Emission Tomography; Protein Binding; Radioactive Tracers; Radiochemistry; Uterine Cervical Neoplasms | 2012 |
Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; beta-Carotene 15,15'-Monooxygenase; Bone Morphogenetic Protein 5; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cornified Envelope Proline-Rich Proteins; Diet; DNA Damage; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gene Expression; Genotype; Intestinal Mucosa; Intestinal Neoplasms; Intestines; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; PPAR alpha; Retinal Dehydrogenase; Retinoids; Up-Regulation | 2013 |
DOTA conjugate with an albumin-binding entity enables the first folic acid-targeted 177Lu-radionuclide tumor therapy in mice.
Topics: Albumins; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Folic Acid; Heterocyclic Compounds, 1-Ring; Humans; KB Cells; Lutetium; Mice; Molecular Targeted Therapy; Multimodal Imaging; Positron-Emission Tomography; Radioisotopes; Tomography, X-Ray Computed | 2013 |
[Interaction of folate deficiency and aberrant profile of DNA methyltransferase 1 in the progression of cervix carcinogenesis].
Topics: Adult; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Folic Acid; Folic Acid Deficiency; Humans; Middle Aged; RNA, Messenger; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2012 |
Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodies.
Topics: Antibodies, Monoclonal; Carrier Proteins; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Down-Regulation; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Neoplasm Proteins; Ovarian Neoplasms; Phenotype; Receptors, Cell Surface; Transfection; Tumor Cells, Cultured | 2003 |
Effects of dietary folate on ulcerative colitis-associated colorectal carcinogenesis in the interleukin 2- and beta(2)-microglobulin-deficient mice.
Topics: Animals; beta 2-Microglobulin; Cell Transformation, Neoplastic; Colitis, Ulcerative; Colorectal Neoplasms; Diet; Dietary Supplements; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Humans; Interleukin-2; Mice; Mice, Inbred C57BL | 2003 |
The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Case-Control Studies; Cell Transformation, Neoplastic; Central Nervous System Neoplasms; DNA, Neoplasm; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Lymphoma; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic | 2004 |
Mandatory fortification with folic acid in the United States is not associated with changes in the degree or the pattern of global DNA methylation in cells involved in cervical carcinogenesis.
Topics: 5-Methylcytosine; Adult; Antibodies, Monoclonal; Cell Transformation, Neoplastic; DNA Methylation; Edible Grain; Female; Folic Acid; Food, Fortified; Humans; Immunohistochemistry; Middle Aged; United States; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2006 |
One-carbon metabolism, colorectal carcinogenesis, chemoprevention--with caution.
Topics: Animals; Betaine; Carbon; Cell Transformation, Neoplastic; Chemoprevention; Choline; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine | 2007 |
Folic acid under scrutiny.
Topics: Cell Transformation, Neoplastic; DNA Methylation; Dose-Response Relationship, Drug; Female; Folic Acid; Humans; Male | 2007 |
Gender-specific modulation of tumorigenesis by folic acid supply in the Apc mouse during early neonatal life.
Topics: Animals; Cell Transformation, Neoplastic; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Growth; Intestinal Neoplasms; Lactation; Male; Mice; Mice, Inbred C57BL; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Sex Factors | 2008 |
Mandatory fortification with folic acid in the United States is associated with increased expression of DNA methyltransferase-1 in the cervix.
Topics: Adult; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Edible Grain; Female; Folic Acid; Food, Fortified; Humans; Immunohistochemistry; United States; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Vitamin B Complex | 2008 |
Expression of folate receptor type alpha in relation to cell type, malignancy, and differentiation in ovary, uterus, and cervix.
Topics: Carrier Proteins; Cell Transformation, Neoplastic; Cervix Uteri; Down-Regulation; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Genital Neoplasms, Female; Humans; In Situ Hybridization; Ovarian Neoplasms; Ovary; Receptors, Cell Surface; RNA Probes; RNA, Messenger; Sensitivity and Specificity; Uterine Cervical Neoplasms; Uterine Neoplasms; Uterus | 1999 |
Folic-acid-mediated inhibition of human colon-cancer cell growth.
Topics: Adenocarcinoma; Animals; Caco-2 Cells; Cell Division; Cell Transformation, Neoplastic; Colonic Neoplasms; Disease Models, Animal; DNA Methylation; Folic Acid; Humans; Tetrahydrofolates | 2001 |
Serum folate and homocysteine levels in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Progression; Female; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Smoking | 2002 |
High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carcinoma 256, Walker; Cell Line; Cell Transformation, Neoplastic; Folic Acid; Homocysteine; Methionine; Simian virus 40 | 1976 |
5-methyltetrahydrofolate: synthesis and utilization in normal and SV40-transformed BHK-21 cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; Folic Acid; Homocysteine; Kidney; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Simian virus 40; Tetrahydrofolates; Vitamin B 12 | 1977 |
Growth limitation of BHK-21 cells and its relation to folate metabolism.
Topics: Aminopterin; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Drug Resistance; Folic Acid; Hypoxanthines; Kidney; Leucovorin; Tetrahydrofolate Dehydrogenase; Thymidine | 1979 |
A method for detecting carcinogenic organic chemicals using mammalian cells in culture.
Topics: Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Folic Acid; Gases; Methods; Nitrosamines; Nitroso Compounds; Vinyl Chloride | 1977 |
[Behavior of deoxyribonuclease I and II during folic acid hyperplasia of the kidney].
Topics: Animals; Cell Transformation, Neoplastic; Deoxyribonucleases; DNA; Female; Folic Acid; Hyperplasia; Kidney Diseases; Kidney Neoplasms; Mice | 1970 |
Roles of calcium, serum, plasma, and folic acid in the control of proliferation of normal and Rous sarcoma virus-infected chicken fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Blood; Calcium; Cell Count; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chickens; Culture Media; Fibroblasts; Folic Acid; Hot Temperature; Plasma; Proteins; Thymidine; Time Factors; Tritium | 1973 |
The biochemist's outlook on cancer research.
Topics: Aerobiosis; Animals; Antineoplastic Agents; Biochemistry; Carbon Radioisotopes; Cell Transformation, Neoplastic; DNA Replication; England; Folic Acid; Folic Acid Antagonists; Glycolysis; History, 20th Century; Humans; Isotope Labeling; Lactates; Leukemia; Mice; Neoplasms; Research; Tetrahydrofolates; Thymidine; Thymidylate Synthase; Thymine; United States | 1973 |
Stimulation of the proliferation of chicken fibroblasts by folic acid or a serum factor(s) in a plasma-containing medium.
Topics: Amino Acids; Animals; Blood; Calcium; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chickens; Culture Media; Fibroblasts; Folic Acid; Kinetics; Plasma; Stimulation, Chemical | 1971 |
Some aspects of the role of folic acid in nucleic acid synthesis in a neoplastic C3H mouse cell strain.
Topics: Animals; Carbon Isotopes; Cell Transformation, Neoplastic; Culture Techniques; DNA, Neoplasm; Folic Acid; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Orotic Acid; RNA, Neoplasm; Thymidine; Uridine | 1968 |