Page last updated: 2024-08-17

folic acid and Carcinoma, Epidermoid

folic acid has been researched along with Carcinoma, Epidermoid in 97 studies

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-199012 (12.37)18.7374
1990's8 (8.25)18.2507
2000's26 (26.80)29.6817
2010's42 (43.30)24.3611
2020's9 (9.28)2.80

Authors

AuthorsStudies
Antonsson, A; Green, AC; Hughes, MCB; Liyanage, UE; Rodriguez-Acevedo, AJ; van der Pols, JC1
Cao, M; Chen, X; He, M; Li, X; Liu, Y; Zhang, X; Zhao, J; Zhao, Q1
Chen, Y; Li, S; Li, X; Yin, D; Yin, Y1
Creeden, JF; Hamouda, D; Lin, L; Nemunaitis, J; Ngo, N; Stanbery, L; Young, O1
Azari, F; Bou-Samra, P; Chang, A; Delikatny, E; Din, A; Doraid, J; Galandarova, A; Ibrahimli, A; Karimov, Z; Kennedy, G; Kucharczuk, J; Nadeem, B; Pechet, T; Singhal, S; Zhang, K1
Ansari, A; Banerjee, R; Bhattacharya, D; Dhiman, C; Kundu, TK; Narayan, KP; Sakhare, K1
Can, O; Gok, O; Guner, R; Sahsuvar, S1
Chen, J; Chen, L; Fan, L; Pu, Y; Wang, J; Wang, Y; Xia, C; Zhang, Q1
Bharadwaj, R; Medhi, S1
Xu, L; Yang, H; Yeudall, WA1
Kairdolf, BA; Lane, LA; Lee, GY; Lu, Q; Nie, S; Peng, X; Wang, J; Wang, Y; Wu, J; Wu, S1
Abnet, CC; Albanes, D; Freedman, ND; Männistö, S; Miranti, EH; Murphy, G; Selhub, J; Stolzenberg-Solomon, R; Taylor, PR; Weinstein, SJ1
Cheng, Z; Ding, X; Fan, C; Su, J; Yu, S; Zhang, S1
Chen, LQ; Hu, WP; Shang, QX; Yang, YS; Yuan, Y1
Cuadros, K; Goral, J; Green, JM; Guimaraes, EP; Hanemann, JAC; Jham, BC; Meyer, A; Pitstick, L1
Hazekawa, M; Kawakubo-Yasukochi, T; Morioka, M; Nakamura, S; Nakashima, M; Nishinakagawa, T; Ohe, K; Ono, K; Ozaki, Y; Yasukochi, A1
Chen, XY; Wen, YY; Yang, SJ; Zhang, JX1
Allen, TC1
Ding, L; Hao, J; Jiang, SW; Wang, JT; Yang, ZK; Zhang, L; Zhao, WM; Zhou, Q1
Cai, HZ; Huang, GL; Su, M; Sun, GJ; Wang, SK; Wang, TT; Yin, H1
Abnet, CC; Freedman, ND; Hollenbeck, AR; Park, Y; Ren, J; Xiao, Q1
Lu, M; Ma, X; Xiang, G; Yang, G; Yang, T; Zhang, W1
Apollo, A; Cox, L; Fury, MG; Haque, S; Ho, AL; Lipson, BL; Lyo, JK; Pfister, DG; Sales, R; Seetharamu, N; Sherman, EJ; Sima, CS; Xiao, H1
Chen, DP; Li, MY; Liang, YY; Liu, JQ; Qi, B; Yin, WJ1
Bai, LX; Chen, C; Chen, X; Ding, L; Gao, CF; Jiang, SW; Kang, HJ; Wang, JT; Zhou, Q1
Bai, L; Chen, X; Ding, L; Sun, X; Wang, J; Wu, T; Xu, J1
Bazi, A; Garme, Y; Khosravi, A; Miri-Moghaddam, E; Motazedian, J; Saravani, S1
Moghanaki, AA; Pourjavadi, A; Tehrani, ZM1
Chen, F; Ding, L; Li, QL; Liang, YL; Liu, CL; Nan, J; Wang, JT; Yang, ZK1
Abnet, CC; Dawsey, SM; Fan, J; Murphy, G; Qiao, Y; Ren, J; Selhub, J; Taylor, PR1
Guan, S; Li, C; Liang, R; Wei, M1
Bossi, P; Licitra, L; Locati, LD; Tagliabue, E1
Chen, Z; Cho, K; Müller, S; Nie, S; Saba, NF; Shin, DM; Tighiouart, M; Wang, X1
Fulmer, AK; Mauldin, GE; Mauldin, GN1
Baker, JR; Dimaggio, S; Holl, MM; Hong, S; Kelly, C; Kotlyar, A; Landmark, KJ; Myc, A; Orr, BG; Penner-Hahn, JE; Thomas, TP; Vogt, S; Ward, J1
Arpicco, S; Brusa, P; Cattel, L; Dosio, F; Stella, B1
Fukui, Y; Jin, M; Kawakami, K; Minamoto, T; Oda, M; Oka, T; Takechi, T; Tsukioka, S; Watanabe, G1
Barata, F; Barlesi, F; Bearz, A; Bepler, G; Chiappori, A; Chouaki, N; Iscoe, N; Liepa, AM; Park, K; Reck, M; Scagliotti, G; Soria, JC; von Pawel, J; Wagle, A; Zhao, YD1
Ghannoum, JE; Odingo, NA; Provost, N1
Allen, N; Altzibar, JM; Barricarte, A; Benetou, V; Boeing, H; Bosch, FX; Boutron-Ruault, MC; Bueno-de-Mesquita, HB; Castellsagué, X; Clavel-Chapelon, F; Dillner, J; Engeset, D; Franceschi, S; González, CA; Hallmans, G; Kaaks, R; Key, TJ; Kjaer, SK; Kjellberg, L; Luján-Barroso, L; Lund, E; Manjer, J; Munk, C; Naska, A; Navarro, C; Olsen, A; Overvad, K; Pala, V; Palli, D; Panico, S; Peeters, PH; Riboli, E; Rinaldi, S; Rodriguez, L; Rohrmann, S; Roura, E; Sacerdote, C; Sanchez, MJ; Skeie, G; Slimani, N; Tjønneland, A; Travier, N; Trichopoulou, A; Tumino, R; van Duijnhoven, FJ1
Green, AC; Hayward, N; Hughes, MC; Ibiebele, TI; Montgomery, G; Pandeya, N; Webb, PM; Whiteman, DC; Zhao, Z1
Akbas, Y; Beyazit, Y; Gorgulu, O; Ozdemir, S; Sayar, C; Selcuk, T1
Lu, C; Shen, H; Wang, F; Wang, J; Xie, H1
Hanai, N; Hasegawa, Y; Hosono, S; Ito, H; Kawakita, D; Matsuo, K; Murakami, S; Oze, I; Sato, F; Tajima, K; Tanaka, H; Watanabe, M; Yatabe, Y1
Ghosh, PC; Tyagi, N1
da Silva, LM; Galbiatti, AL; Goloni-Bertollo, EM; Maniglia, JV; Pavarino, EC; Raposo, LS; Ruiz, MT1
Ding, L; Fan, JR; Hao, M; Huo, XX; Wang, JT; Zhang, L; Zhao, WM1
Azzoli, CG; Dunne, M; Ginsberg, M; Huntington, M; James, L; Kris, MG; Krug, LM; May, J; Miller, V; Patel, JD; Saunders, M; Sirotnak, FM; Subzwari, S; Tyson, L1
Hasegawa, Y; Hosono, S; Ito, H; La Vecchia, C; Matsuo, K; Negri, E; Oze, I; Rossi, M; Tajima, K; Tanaka, H; Watanabe, M; Yatabe, Y1
da Silva, LM; Galbiatti, AL; Goloni-Bertollo, EM; Maníglia, JV; Pavarino, EC; Raposo, LS; Ruiz-Cintra, MT1
Asomaning, K; Christiani, DC; Lee, MS; Mark, EJ; Su, L; Wain, JC1
Gotay, C; Hajizadeh, B; Jessri, M; Rashidkhani, B1
Duarte, S; Faneca, H; Lima, MC1
Bergman, CJ; Chang, S; Hajibandeh, J; Keiserman, MA; Kingsley, K; McCabe, J; Meeder, CA; Moody, M; Nguyen, DH; Sharma, K; Tran, MD1
Duan, Y; Huang, Z; Jiang, J; Jing, C; Xiao, X; Zhang, R1
Cagle, PT; Low, PS; Murphy, L; Zhai, QJ1
Chen, J; Duan, YQ; Huang, ZJ; Jiang, JQ; Xiao, XR; Zhang, R1
Ding, L; Hao, JX; Hao, M; Wang, JT; Zhao, WM; Zhou, Q1
Bollschweiler, E; Hölscher, AH; Mönig, SP; Nowroth, T; Rosendahl, U; Wolfgarten, E1
Frick, B; Fuchs, D; Schröcksnadel, K1
Lee, RJ; Pan, XQ; Wang, H1
Bavetsias, V; Gibbs, D; Jackman, AL; Jansen, G; Skelton, LA; Theti, DS; Titley, J1
CONDIT, PT; OWENS, AH; SHNIDER, BI1
BERTINO, JR; HELLMAN, S; IANNOTTI, AT1
DELLER, DJ; WANGEL, AG1
Almadori, G; Bussu, F; Cadoni, G; Galli, J; Giardina, B; Maurizi, M; Minucci, A; Persichilli, S; Zappacosta, B1
Kane, MA1
Franceschi, S; Galeone, C; La Vecchia, C; Levi, F; Negri, E; Pelucchi, C; Talamini, R1
Brown, KS; Kane, MA1
Hsiung, D; Kelsey, KT; Kraunz, KS; Liu, M; McClean, MD; Nelson, HH; Osanyingbemi, J1
Giovannucci, E; Larsson, SC; Wolk, A1
Hida, T; Hiraki, A; Matsuo, K; Mitsudomi, T; Saito, T; Sato, S; Suzuki, T; Tajima, K; Ueda, R; Yatabe, Y1
Hasegawa, Y; Hiraki, A; Hirose, K; Matsuo, K; Saito, T; Sato, S; Suzuki, T; Tajima, K; Ueda, R; Wakai, K1
Chayama, K; Hiyama, T; Tanaka, S; Yoshihara, M1
Baker, JA; Brasure, JR; Ghosh, C; McCann, SE; Moysich, KB; Rivera, R1
Kamen, BA; Kreisler, AR; Orr, RB1
Kamen, BA; Orr, RB2
Capizzi, RL; George, T; Kamen, BA; McGuirt, F; Schifeling, DJ1
Faessel, HM; Greco, WR; Rustum, YM; Slocum, HK1
Michael, CW; Reynolds, RK; Rock, CL; Ruffin, MT1
Backus, HH; Jansen, G; Molders, N; Padrón, JM; Peters, GJ; Pinedo, HM; van Der Wilt, CL; van Groeningen, CJ; Wouters, D1
Grizzle, WE; Heimburger, DC; Johanning, GL; Macaluso, M; Oelschlager, DK; Piyathilake, CJ; Whiteside, M1
Bisogni, CA; Brinton, LA; Colman, N; Frongillo, EA; Hamman, RF; Levine, RS; Mallin, K; Sauberlich, HE; Stolley, PD; Weinstein, SJ; Ziegler, RG1
Almadori, G; Bussu, F; Cadoni, G; Galli, J; Giardina, B; Minucci, A; Persichilli, S; Zappacosta, B1
Snow, GB; van der Vijgh, WJ; Versluis, RJ1
Hordijk, GJ; Jansen, G; Kathmann, GA; Schornagel, JH; van der Laan, BF; Westerhof, GR1
Brenes, MM; Brinton, LA; de Britton, RC; Gaitan, E; Herrero, R; Potischman, N; Reeves, WC; Tenorio, F1
Brenes, MM; Brinton, LA; de Britton, RC; Gaitan, E; Herrero, R; Laiming, VA; Potischman, N; Reeves, WC; Tenorio, F1
Kane, MA; Raptis, G; Roth, E; Schreiber, C; Waxman, S1
FitzGerald, GB; Wick, MM1
Antony, AC; Elwood, PC; Finley, A; Kane, MA; Kolhouse, JF; Najfeld, V; Portillo, RM; Waxman, S1
Hartenstein, RC; Rohloff, R; Trott, KR; Wendt, TG; Wustrow, TP1
Antony, AC; Elwood, PC; Kane, MA; Kolhouse, JF; Portillo, RM2
Battesti, JP; Turiaf, J1
Joseph, LB; Simon, GT; Singh, AD; Singh, SP; Von Essen, CF1

Reviews

8 review(s) available for folic acid and Carcinoma, Epidermoid

ArticleYear
Folate Receptor as a Biomarker and Therapeutic Target in Solid Tumors.
    Current problems in cancer, 2023, Volume: 47, Issue:1

    Topics: Biomarkers; Carcinoma, Squamous Cell; Folic Acid; Folic Acid Antagonists; Humans; Prognosis

2023
Association between folate intake and risk of head and neck squamous cell carcinoma: An overall and dose-response PRISMA meta-analysis.
    Medicine, 2017, Volume: 96, Issue:42

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Diet; Dose-Response Relationship, Drug; Eating; Female; Folic Acid; Folic Acid Deficiency; Head and Neck Neoplasms; Humans; Male; Middle Aged; Observational Studies as Topic; Odds Ratio; Risk Factors; Squamous Cell Carcinoma of Head and Neck

2017
Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: a meta-analysis of case-control studies.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:1

    Topics: Carcinoma, Squamous Cell; Case-Control Studies; Confidence Intervals; Diet; Esophageal Neoplasms; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors

2013
The role of folates in squamous cell carcinoma of the head and neck.
    Cancer detection and prevention, 2005, Volume: 29, Issue:1

    Topics: Alcohol Drinking; Carcinoma, Squamous Cell; Chemoprevention; Folic Acid; Folic Acid Deficiency; Head and Neck Neoplasms; Humans; Risk Factors; Smoking

2005
Chemoprevention of squamous cell carcinoma of the oral cavity.
    Otolaryngologic clinics of North America, 2006, Volume: 39, Issue:2

    Topics: Antineoplastic Agents; Ascorbic Acid; Carcinoma, Squamous Cell; Drugs, Chinese Herbal; Flavonoids; Folic Acid; Humans; Mouth Neoplasms; Precancerous Conditions; Retinoids; Selenium; Vitamin A; Vitamin E

2006
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
    Gastroenterology, 2006, Volume: 131, Issue:4

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Case-Control Studies; Esophageal Neoplasms; Folic Acid; Gastrointestinal Neoplasms; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Pancreatic Neoplasms; Polymorphism, Genetic; Risk Factors; Stomach Neoplasms

2006
Genetic polymorphisms and esophageal cancer risk.
    International journal of cancer, 2007, Oct-15, Volume: 121, Issue:8

    Topics: Adenocarcinoma; Alcohol Oxidoreductases; Carcinoma, Squamous Cell; Cytochrome P-450 Enzyme System; DNA Repair; Esophageal Neoplasms; Folic Acid; Genes, cdc; Genetic Predisposition to Disease; Humans; Meta-Analysis as Topic; Odds Ratio; Oncogenes; Polymorphism, Genetic; Risk Factors

2007
Prevention of cervix cancer.
    Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:3

    Topics: Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; beta Carotene; Carcinoma, Squamous Cell; Clinical Trials as Topic; Colposcopy; Diet; Female; Folic Acid; Humans; Image Processing, Computer-Assisted; Mass Screening; Nutritional Requirements; Papanicolaou Test; Papillomaviridae; Papillomavirus Infections; Photochemotherapy; Risk Factors; Tumor Virus Infections; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Vaginal Smears; Viral Vaccines; Vitamin E; Vitamins

2000

Trials

6 trial(s) available for folic acid and Carcinoma, Epidermoid

ArticleYear
Low vitamin B
    International journal of cancer, 2017, 09-15, Volume: 141, Issue:6

    Topics: Aged; alpha-Tocopherol; beta Carotene; Carcinoma, Squamous Cell; Case-Control Studies; Dietary Supplements; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Finland; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Riboflavin; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency

2017
A phase II study of pralatrexate with vitamin B12 and folic acid supplementation for previously treated recurrent and/or metastatic head and neck squamous cell cancer.
    Investigational new drugs, 2014, Volume: 32, Issue:3

    Topics: Adult; Aged; Aminopterin; Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck; Vitamin B 12; Vitamin B Complex; Young Adult

2014
Glycididazole sodium combined with radiochemotherapy for locally advanced nasopharyngeal carcinoma.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Case-Control Studies; Chemoradiotherapy; Cisplatin; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Humans; Male; Metronidazole; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Staging; Prognosis; Survival Rate

2014
Phase II, double-blinded, randomized study of enzastaurin plus pemetrexed as second-line therapy in patients with advanced non-small cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2010, Volume: 5, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Double-Blind Method; Female; Folic Acid; Glutamates; Guanine; Humans; Indoles; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Pemetrexed; Prognosis; Salvage Therapy; Survival Rate; Vitamin B 12

2010
Pralatrexate with vitamin supplementation in patients with previously treated, advanced non-small cell lung cancer: safety and efficacy in a phase 1 trial.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2011, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Tissue Distribution; Vitamin B 12; Vitamin B Complex

2011
Vitamin intake and risk of subtypes of esophageal cancer in Germany.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:10

    Topics: Adenocarcinoma; Adult; Alcohol Drinking; Ascorbic Acid; Body Mass Index; Carcinoma, Squamous Cell; Case-Control Studies; Dietary Supplements; Esophageal Neoplasms; Folic Acid; Germany; Humans; Incidence; Male; Pilot Projects; Risk Factors; Smoking; Surveys and Questionnaires; Vitamin A; Vitamin E

2002

Other Studies

83 other study(ies) available for folic acid and Carcinoma, Epidermoid

ArticleYear
Dark Green Leafy Vegetable Intake, MTHFR Genotype, and Risk of Cutaneous Squamous Cell Carcinoma.
    Dermatology (Basel, Switzerland), 2022, Volume: 238, Issue:4

    Topics: Australia; Carcinoma, Squamous Cell; Case-Control Studies; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Skin Neoplasms; Vegetables

2022
Folate Receptor 4-Expressing T cell Is Associated with Disease-Free Survival in Patients with Esophageal Squamous Cell Carcinoma.
    Disease markers, 2022, Volume: 2022

    Topics: Carcinoma, Squamous Cell; Disease-Free Survival; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Folic Acid; Humans; Prognosis; Retrospective Studies

2022
Dietary habits, nutrition and esophageal cancer: A case-control study on Kazakhs in Xinjiang.
    Cancer epidemiology, 2022, Volume: 81

    Topics: Carcinoma, Squamous Cell; Case-Control Studies; Esophageal Neoplasms; Feeding Behavior; Folic Acid; Humans; Nutritional Status; Risk Factors

2022
Prospective validation of tumor folate receptor expression density with the association of pafolacianine fluorescence during intraoperative molecular imaging-guided lung cancer resections.
    European journal of nuclear medicine and molecular imaging, 2023, Volume: 50, Issue:8

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Folic Acid; Humans; Lung Neoplasms; Molecular Imaging; Prospective Studies

2023
Delivery of chemotherapeutic drug targeting folate receptor to oral cancer cells using functionalized carbon nanospheres.
    Biomedical materials (Bristol, England), 2023, 08-02, Volume: 18, Issue:5

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Folic Acid; Ligands; Mice; Mouth Neoplasms; Nanospheres

2023
Development and pharmaceutical investigation of novel cervical cancer-targeting and redox-responsive melittin conjugates.
    Scientific reports, 2023, 10-25, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Female; Folic Acid; HeLa Cells; Humans; Melitten; Oxidation-Reduction; Pharmaceutical Preparations; Uterine Cervical Neoplasms

2023
Glutathione-sensitive and folate-targeted nanoparticles loaded with paclitaxel to enhance oral squamous cell carcinoma therapy.
    Journal of materials chemistry. B, 2020, 04-21, Volume: 8, Issue:15

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Proliferation; Drug Liberation; Drug Screening Assays, Antitumor; Folic Acid; Glutathione; Humans; Male; Mice; Mice, Inbred BALB C; Mouth Neoplasms; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Particle Size; Surface Properties; Tumor Cells, Cultured

2020
Effectual nanotherapy against oral squamous cell carcinoma.
    Drug development and industrial pharmacy, 2021, Volume: 47, Issue:5

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Carriers; Folic Acid; Head and Neck Neoplasms; Mouth Neoplasms; Nanoparticles; Paclitaxel; Squamous Cell Carcinoma of Head and Neck; Tissue Distribution

2021
Folic acid-decorated polyamidoamine dendrimer exhibits high tumor uptake and sustained highly localized retention in solid tumors: Its utility for local siRNA delivery.
    Acta biomaterialia, 2017, 07-15, Volume: 57

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Dendrimers; Female; Folic Acid; Gene Transfer Techniques; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Proteins; Neovascularization, Pathologic; Polyamines; RNA, Small Interfering; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2017
Quantitative Examination of the Active Targeting Effect: The Key Factor for Maximal Tumor Accumulation and Retention of Short-Circulated Biopolymeric Nanocarriers.
    Bioconjugate chemistry, 2017, 05-17, Volume: 28, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Drug Carriers; Drug Delivery Systems; Folic Acid; Heparin; Humans; Mice; Mice, Nude; Nanoparticles; Polymers; Tissue Distribution

2017
The role of mitochondrial folate enzyme MTHFD1L in esophageal squamous cell carcinoma.
    Scandinavian journal of gastroenterology, 2018, Volume: 53, Issue:5

    Topics: Aged; Aged, 80 and over; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Minor Histocompatibility Antigens; Mitochondria; Quality of Life; RNA, Small Interfering

2018
Decreased expression of folate transport proteins in oral cancer.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2019, Volume: 127, Issue:5

    Topics: Carcinoma, Squamous Cell; Folic Acid; Folic Acid Antagonists; Folic Acid Transporters; Humans; Mouth Neoplasms; Reduced Folate Carrier Protein

2019
Maternal folic acid depletion during early pregnancy increases sensitivity to squamous tumor formation in the offspring in mice.
    Journal of developmental origins of health and disease, 2019, Volume: 10, Issue:6

    Topics: Animals; Animals, Newborn; Carcinoma, Squamous Cell; Female; Folic Acid; Folic Acid Deficiency; Male; Maternal Nutritional Physiological Phenomena; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Skin Neoplasms; Tongue Neoplasms

2019
Targeted molecular therapy for lung cancer: exuberance reestablished.
    Archives of pathology & laboratory medicine, 2013, Volume: 137, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation, Preclinical; Female; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms; Male; Neoplasms

2013
Folate deficiency and aberrant expression of DNA methyltransferase 1 were associated with cervical cancerization.
    Current pharmaceutical design, 2014, Volume: 20, Issue:11

    Topics: Adult; Aged; Carcinoma, Squamous Cell; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; RNA, Messenger; Severity of Illness Index; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2014
Serum folate, MTHFR C677T polymorphism and esophageal squamous cell carcinoma risk.
    Biomedical and environmental sciences : BES, 2013, Volume: 26, Issue:12

    Topics: Carcinoma, Squamous Cell; Chi-Square Distribution; Esophageal Neoplasms; Folic Acid; Genetic Predisposition to Disease; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic

2013
Intakes of folate, methionine, vitamin B6, and vitamin B12 with risk of esophageal and gastric cancer in a large cohort study.
    British journal of cancer, 2014, Mar-04, Volume: 110, Issue:5

    Topics: Carcinoma, Squamous Cell; Cohort Studies; Diet; Esophageal Neoplasms; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Risk; Stomach Neoplasms; United States; Vitamin B 12; Vitamin B 6

2014
In vitro and in vivo antitumor effects of folate-targeted ursolic acid stealth liposome.
    Journal of agricultural and food chemistry, 2014, Mar-12, Volume: 62, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Area Under Curve; Biological Availability; Carcinoma, Squamous Cell; Cholesterol Esters; Drug Delivery Systems; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Liposomes; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Mouth Neoplasms; Polyethylene Glycols; Solubility; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays

2014
Folate deficiency and FHIT hypermethylation and HPV 16 infection promote cervical cancerization.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:21

    Topics: Acid Anhydride Hydrolases; Adult; Carcinoma, Squamous Cell; Cohort Studies; CpG Islands; Disease Progression; DNA Methylation; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Human papillomavirus 16; Humans; Middle Aged; Neoplasm Proteins; Papillomavirus Infections; Polymerase Chain Reaction; Sensitivity and Specificity; Uterine Cervical Neoplasms

2014
[Interaction between folate deficiency and aberrant expression related to fragile histidine triad gene in the progression of cervical cancerization].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2015, Volume: 36, Issue:4

    Topics: Acid Anhydride Hydrolases; Apoptosis; Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Deficiency; Human papillomavirus 16; Humans; Neoplasm Proteins; Polymerase Chain Reaction; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2015
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms in oral squamous cell carcinoma in south-east Iran.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2016, Volume: 45, Issue:2

    Topics: Adult; Aged; Alleles; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; Head and Neck Neoplasms; Humans; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mouth Neoplasms; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Factors; Squamous Cell Carcinoma of Head and Neck

2016
Folate-Conjugated pH-Responsive Nanocarrier Designed for Active Tumor Targeting and Controlled Release of Gemcitabine.
    Pharmaceutical research, 2016, Volume: 33, Issue:2

    Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Delayed-Action Preparations; Deoxycytidine; Drug Delivery Systems; Folic Acid; Gemcitabine; Graphite; Humans; Hydrogen-Ion Concentration; Nanoparticles; Polyethylene Glycols; Silicon Dioxide

2016
[Relationship and interaction between folate and expression of methyl-CpG-binding protein 2 in cervical cancerization].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2016, Volume: 37, Issue:7

    Topics: Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Deficiency; Humans; Methyl-CpG-Binding Protein 2; Polymerase Chain Reaction; RNA, Messenger; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2016
Prospective study of serum B vitamins levels and oesophageal and gastric cancers in China.
    Scientific reports, 2016, 10-17, Volume: 6

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Cardia; China; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Flavin Mononucleotide; Folic Acid; Humans; Male; Middle Aged; Niacin; Proportional Hazards Models; Prospective Studies; Pyridoxal Phosphate; Riboflavin; Stomach Neoplasms; Vitamin B 12; Vitamin B Complex

2016
A supramolecular material for dual-modal imaging and targeted cancer therapy.
    Talanta, 2017, Apr-01, Volume: 165

    Topics: Carcinoma, Squamous Cell; Cell Survival; Dextrans; Doxorubicin; Fluorescein-5-isothiocyanate; Folic Acid; Gadolinium; Humans; Hydroxides; Intercalating Agents; Magnetic Resonance Imaging; Optical Imaging; Tumor Cells, Cultured

2017
Folate in head and neck squamous cell cancer chemoprevention: purposely left out?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jul-10, Volume: 26, Issue:20

    Topics: Carcinoma, Squamous Cell; Chemoprevention; Folic Acid; Folic Acid Deficiency; Head and Neck Neoplasms; Humans; Risk Assessment; Sensitivity and Specificity

2008
Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug.
    Head & neck, 2009, Volume: 31, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lymphatic Metastasis; Male; Middle Aged; Nanomedicine; Nanotechnology; Paclitaxel; Receptors, Cell Surface; Young Adult

2009
Evaluation of plasma folate and homocysteine concentrations in cats with and without oral squamous cell carcinoma.
    Veterinary and comparative oncology, 2008, Volume: 6, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cat Diseases; Cats; Female; Folic Acid; Homocysteine; Male; Mouth Neoplasms

2008
Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers.
    ACS nano, 2008, Volume: 2, Issue:4

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Contrast Media; Crystallization; Drug Carriers; Ferric Compounds; Folic Acid; Humans; Macromolecular Substances; Magnetic Resonance Imaging; Magnetics; Materials Testing; Molecular Conformation; Nanomedicine; Nanostructures; Particle Size; Surface Properties

2008
Folate-mediated targeting of albumin conjugates of paclitaxel obtained through a heterogeneous phase system.
    International journal of pharmaceutics, 2009, Dec-01, Volume: 382, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Carrier Proteins; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Chromatography, Gel; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Folate Receptors, GPI-Anchored; Folic Acid; HT29 Cells; Humans; Inhibitory Concentration 50; KB Cells; Nasopharyngeal Neoplasms; Paclitaxel; Polyethylene Glycols; Receptors, Cell Surface; Serum Albumin; Solubility; Technology, Pharmaceutical; Triazines

2009
Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels.
    Cancer science, 2009, Volume: 100, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Cadherins; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Core Binding Factor Alpha 3 Subunit; DNA Methylation; Female; Folic Acid; Humans; Immunohistochemistry; Long Interspersed Nucleotide Elements; Lung Neoplasms; Male; Middle Aged

2009
Clinico-pathologic conference: case 6.
    Head and neck pathology, 2009, Volume: 3, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell; Carpal Tunnel Syndrome; Clonidine; Dermatomyositis; Diabetes Mellitus, Type 1; Diagnosis, Differential; Edema; Exanthema; Face; Female; Folic Acid; Hematinics; Humans; Hypertension; Hypoglycemic Agents; Hypothyroidism; Insulin; Lupus Erythematosus, Discoid; Middle Aged; Neoplasms, Unknown Primary; Paraneoplastic Syndromes; Radiotherapy, Intensity-Modulated; Skin Neoplasms; Thyroxine

2009
Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study.
    International journal of cancer, 2011, Jul-15, Volume: 129, Issue:2

    Topics: Adult; Aged; Ascorbic Acid; beta Carotene; Carcinoma; Carcinoma, Squamous Cell; Diet; Europe; Female; Folic Acid; Follow-Up Studies; Fruit; Humans; Middle Aged; Neoplasm Invasiveness; Nutrition Surveys; Prospective Studies; Risk Factors; Uterine Cervical Neoplasms; Vegetables; Vitamin A; Vitamin D; Vitamin E

2011
High intake of folate from food sources is associated with reduced risk of esophageal cancer in an Australian population.
    The Journal of nutrition, 2011, Volume: 141, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Alcohol Drinking; Australia; Barrett Esophagus; Betaine; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Dietary Supplements; Esophageal Neoplasms; Esophagus; Female; Folic Acid; Humans; Logistic Models; Male; Methionine; Middle Aged; Risk Factors; Smoking; Vitamin B Complex

2011
Evaluation of the roles of serum vitamin B(12), folate and homocysteine levels in laryngeal squamous cell carcinoma.
    The Journal of international medical research, 2010, Volume: 38, Issue:6

    Topics: Carcinoma, Squamous Cell; Case-Control Studies; Demography; Folic Acid; Homocysteine; Humans; Laryngeal Neoplasms; Middle Aged; Vitamin B 12

2010
Diet folate, DNA methylation and genetic polymorphisms of MTHFR C677T in association with the prognosis of esophageal squamous cell carcinoma.
    BMC cancer, 2011, Mar-05, Volume: 11

    Topics: Adaptor Proteins, Signal Transducing; Aged; Carcinoma, Squamous Cell; Diet; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Eating; Esophageal Neoplasms; Female; Folic Acid; Genes, p16; Genetic Association Studies; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; MutL Protein Homolog 1; Nuclear Proteins; Polymorphism, Single Nucleotide; Prognosis; Tumor Suppressor Proteins

2011
Association between dietary folate intake and clinical outcome in head and neck squamous cell carcinoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:1

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cohort Studies; Diet; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Minor Histocompatibility Antigens; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Surveys and Questionnaires; Thymidylate Synthase; Young Adult

2012
Folate receptor mediated targeted delivery of ricin entrapped into sterically stabilized liposomes to human epidermoid carcinoma (KB) cells: effect of monensin intercalated into folate-tagged liposomes.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Jul-17, Volume: 43, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Folic Acid; Folic Acid Transporters; Humans; Intercalating Agents; Liposomes; Monensin; Phosphatidylethanolamines; Polyethylene Glycols; Ricin

2011
MTHFD1 G1958A, BHMT G742A, TC2 C776G and TC2 A67G polymorphisms and head and neck squamous cell carcinoma risk.
    Molecular biology reports, 2012, Volume: 39, Issue:2

    Topics: Betaine-Homocysteine S-Methyltransferase; Brazil; Carcinoma, Squamous Cell; DNA Methylation; Female; Folic Acid; Genomic Instability; Head and Neck Neoplasms; Humans; Logistic Models; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Transcobalamins

2012
[Effect of folic acid and DNA methyltransferase 1 on cervical cancer and its precancerous lesion].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2011, Volume: 32, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Folic Acid; Humans; Middle Aged; Precancerous Conditions; Uterine Cervical Neoplasms

2011
Folate, alcohol, and aldehyde dehydrogenase 2 polymorphism and the risk of oral and pharyngeal cancer in Japanese.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2012, Volume: 21, Issue:2

    Topics: Adult; Aged; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Asian People; Carcinoma; Carcinoma, Squamous Cell; Case-Control Studies; Eating; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms; Polymorphism, Single Nucleotide; Risk Factors; Squamous Cell Carcinoma of Head and Neck; Young Adult

2012
Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk.
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:10

    Topics: Aged; Alleles; Carcinoma, Squamous Cell; Case-Control Studies; DNA Methylation; Female; Folic Acid; Gene Deletion; Genotype; Head and Neck Neoplasms; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Statistical; Polymorphism, Genetic; Regression Analysis; Risk; Squamous Cell Carcinoma of Head and Neck; Time Factors; Treatment Outcome

2012
MTHFR polymorphisms, folate intake and carcinogen DNA adducts in the lung.
    International journal of cancer, 2012, Sep-01, Volume: 131, Issue:5

    Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Case-Control Studies; DNA Adducts; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Lung; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Staging; Polymorphism, Genetic; Prognosis; Risk Factors; Smoking

2012
Macronutrients, vitamins and minerals intake and risk of esophageal squamous cell carcinoma: a case-control study in Iran.
    Nutrition journal, 2011, Dec-20, Volume: 10

    Topics: Aged; alpha-Tocopherol; beta Carotene; Carcinoma, Squamous Cell; Case-Control Studies; Confidence Intervals; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Energy Intake; Esophageal Neoplasms; Feeding Behavior; Female; Folic Acid; Hospitalization; Humans; Incidence; Interviews as Topic; Iran; Logistic Models; Male; Micronutrients; Middle Aged; Odds Ratio; Pilot Projects; Risk Factors; Selenium; Surveys and Questionnaires; Vitamin E; Vitamins

2011
Folate-associated lipoplexes mediate efficient gene delivery and potent antitumoral activity in vitro and in vivo.
    International journal of pharmaceutics, 2012, Feb-28, Volume: 423, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Survival; Cholesterol; Connexin 43; DNA; Female; Folate Receptors, GPI-Anchored; Folic Acid; Genes, Reporter; Genes, Transgenic, Suicide; Genetic Therapy; Mice; Mice, Inbred C3H; Mouth Neoplasms; Phosphatidylcholines; Thymidine Kinase; Time Factors; Transfection; Viral Proteins

2012
Folate supplementation induces differential dose-dependent modulation of proliferative phenotypes among cancerous and noncancerous oral cell lines in vitro.
    Journal of dietary supplements, 2010, Volume: 7, Issue:4

    Topics: Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mouth Neoplasms; Phenotype; Polymorphism, Genetic; RNA, Messenger; Tumor Suppressor Protein p53; Vitamin B Complex

2010
Folate intake, methylenetetrahydrofolate reductase polymorphisms in association with the prognosis of esophageal squamous cell carcinoma.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:2

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Squamous Cell; China; Cohort Studies; Esophageal Neoplasms; Female; Folic Acid; Follow-Up Studies; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prognosis

2012
Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents.
    Archives of pathology & laboratory medicine, 2013, Volume: 137, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Folate Receptor 1; Folic Acid; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Tissue Array Analysis

2013
Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism and folate intake in esophageal squamous cell carcinoma.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Carcinoma, Squamous Cell; Case-Control Studies; Cyclin-Dependent Kinase Inhibitor p16; DNA; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Esophageal Neoplasms; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; MutL Protein Homolog 1; Neoplasm Proteins; Neoplasm Staging; Nuclear Proteins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prognosis; Risk Factors; Tumor Suppressor Proteins

2012
[Interaction of folate deficiency and aberrant profile of DNA methyltransferase 1 in the progression of cervix carcinogenesis].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2012, Volume: 46, Issue:12

    Topics: Adult; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Folic Acid; Folic Acid Deficiency; Humans; Middle Aged; RNA, Messenger; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2012
Serum folate and homocysteine levels in head and neck squamous cell carcinoma.
    Cancer, 2002, Nov-15, Volume: 95, Issue:10

    Topics: Carcinoma, Squamous Cell; Disease Progression; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Hyperhomocysteinemia; Neopterin; Prognosis; Risk Factors

2002
Antitumor activity of folate receptor-targeted liposomal doxorubicin in a KB oral carcinoma murine xenograft model.
    Pharmaceutical research, 2003, Volume: 20, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Carrier Proteins; Doxorubicin; Fluorometry; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Injections, Intraperitoneal; KB Cells; Liposomes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Neoplasm Transplantation; Receptors, Cell Surface; Survival Analysis; Time Factors; Xenograft Model Antitumor Assays

2003
Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the alpha-isoform of the folate receptor.
    Cancer research, 2003, Jul-01, Volume: 63, Issue:13

    Topics: Antineoplastic Agents; Biological Transport; Carcinoma, Squamous Cell; Carrier Proteins; Cell Division; Cyclopentanes; Enzyme Inhibitors; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Kinetics; Quinazolines; Receptors, Cell Surface; Recombinant Proteins; Thymidylate Synthase; Transfection; Tumor Cells, Cultured; Vulvar Neoplasms

2003
Studies on the folic acid vitamins. VII. The effects of large doses of amethopterin in patients with cancer.
    Cancer research, 1962, Volume: 22

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Folic Acid; Folic Acid Antagonists; Methotrexate; Neomycin; Neoplasms; Vitamins

1962
DETERMINATIONS OF THE LEVELS OF SERUM FOLATE IN PATIENTS WITH CARCINOMA OF THE HEAD AND NECK TREATED WITH METHOTREXATE.
    Cancer research, 1964, Volume: 24

    Topics: Blood Chemical Analysis; Carcinoma, Squamous Cell; Folic Acid; Humans; Methotrexate; Nasopharyngeal Neoplasms; Neoplasms; Nose Neoplasms; Osteosarcoma; Pathology; Pharmacology; Pharyngeal Neoplasms; Sarcoma; Tongue Neoplasms

1964
MALABSORPTION SYNDROME ASSOCIATED WITH CARCINOMA OF THE BRONCHUS.
    Gut, 1965, Volume: 6

    Topics: Anemia; Anemia, Macrocytic; Blood Chemical Analysis; Bronchi; Bronchial Neoplasms; Carcinoma, Squamous Cell; Celiac Disease; Feces; Fluids and Secretions; Folic Acid; Folic Acid Deficiency; Humans; Hypokalemia; Hypoproteinemia; Jejunum; Lipid Metabolism; Malabsorption Syndromes; Pathology; Urine; Vitamin B 12

1965
Serum levels of folate, homocysteine, and vitamin B12 in head and neck squamous cell carcinoma and in laryngeal leukoplakia.
    Cancer, 2005, Jan-15, Volume: 103, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Laryngeal Neoplasms; Leukoplakia; Male; Middle Aged; Prognosis; Reference Values; Risk Assessment; Sensitivity and Specificity; Vitamin B 12

2005
Folate intake and squamous-cell carcinoma of the oesophagus in Italian and Swiss men.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:3

    Topics: Alcohol Drinking; Carcinoma, Squamous Cell; Case-Control Studies; Esophageal Neoplasms; Folic Acid; Humans; Italy; Male; Methionine; Middle Aged; Switzerland; Vitamin B 6

2006
Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma.
    International journal of cancer, 2006, Oct-01, Volume: 119, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Diet; DNA Methylation; Female; Folic Acid; Genotype; Head and Neck Neoplasms; Humans; Male; Methylation; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors

2006
Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case control study.
    Carcinogenesis, 2007, Volume: 28, Issue:8

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoma, Large Cell; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Japan; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Random Allocation; Risk Factors

2007
One-carbon metabolism-related gene polymorphisms and risk of head and neck squamous cell carcinoma: case-control study.
    Cancer science, 2007, Volume: 98, Issue:9

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alcohol Drinking; Carbon; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Random Allocation; Risk Factors; Thymidylate Synthase

2007
Dietary intakes of selected nutrients and food groups and risk of cervical cancer.
    Nutrition and cancer, 2008, Volume: 60, Issue:3

    Topics: Ascorbic Acid; Carcinoma, Squamous Cell; Carotenoids; Case-Control Studies; Confidence Intervals; Diet; Dietary Fiber; Female; Folic Acid; Fruit; Humans; Logistic Models; Menopause; Middle Aged; Odds Ratio; Risk Factors; Surveys and Questionnaires; Uterine Cervical Neoplasms; Vegetables; Vitamin A; Vitamin E

2008
Similarity of folate receptor expression in UMSCC 38 cells to squamous cell carcinoma differentiation markers.
    Journal of the National Cancer Institute, 1995, Feb-15, Volume: 87, Issue:4

    Topics: Antigens, Differentiation; Blotting, Northern; Carcinoma, Squamous Cell; Carrier Proteins; Electrophoresis, Polyacrylamide Gel; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Receptors, Cell Surface; Tretinoin; Tumor Cells, Cultured

1995
Identification of a point mutation in the folate receptor gene that confers a dominant negative phenotype.
    Cancer research, 1995, Feb-15, Volume: 55, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Carrier Proteins; CHO Cells; Cricetinae; DNA, Complementary; Folate Receptors, GPI-Anchored; Folic Acid; Genes, Dominant; Glycosylphosphatidylinositols; Haplorhini; Humans; Phenotype; Point Mutation; Receptors, Cell Surface; Tetrahydrofolates; Transfection; Tritium

1995
UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor.
    Cancer research, 1994, Jul-15, Volume: 54, Issue:14

    Topics: Base Sequence; Biological Transport; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 11; DNA, Complementary; Folate Receptors, GPI-Anchored; Folic Acid; Gene Amplification; Humans; Molecular Sequence Data; Mutation; Receptors, Cell Surface; Tetrahydrofolates; Tumor Cells, Cultured

1994
Methotrexate content in squamous cell carcinoma of the head and neck after low-dose methotrexate.
    Medical and pediatric oncology, 1994, Volume: 22, Issue:2

    Topics: Administration, Oral; Adult; Carcinoma, Squamous Cell; Female; Folic Acid; Head and Neck Neoplasms; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Mucous Membrane

1994
Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5,4,6][1,4]thiazin -6-yl)-(S)-ethyl]-2,5-thienoylamino-L-glutamic acid (AG
    Biochemical pharmacology, 1999, Mar-01, Volume: 57, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Drug Resistance, Multiple; Drug Synergism; Folic Acid; Folic Acid Antagonists; Glutamates; Head and Neck Neoplasms; Humans; Hydroxymethyl and Formyl Transferases; Kinetics; Lung Neoplasms; Phosphoribosylglycinamide Formyltransferase; Pyrimidines; Trimetrexate; Tumor Cells, Cultured

1999
Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.
    International journal of cancer, 2000, Sep-15, Volume: 87, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Colonic Neoplasms; Fluorouracil; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leucovorin; Lung Neoplasms; Membrane Proteins; Membrane Transport Proteins; Mice; Multienzyme Complexes; Neoplasms; Peptide Synthases; Reduced Folate Carrier Protein; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured

2000
Localized folate and vitamin B-12 deficiency in squamous cell lung cancer is associated with global DNA hypomethylation.
    Nutrition and cancer, 2000, Volume: 37, Issue:1

    Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; DNA Methylation; Folic Acid; Folic Acid Deficiency; Humans; Lung Neoplasms; Middle Aged; Smoking; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency

2000
Low serum and red blood cell folate are moderately, but nonsignificantly associated with increased risk of invasive cervical cancer in U.S. women.
    The Journal of nutrition, 2001, Volume: 131, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Viral; Bacteriological Techniques; Carcinoma, Squamous Cell; Case-Control Studies; Erythrocytes; Female; Folic Acid; Humans; Interviews as Topic; Middle Aged; Neoplasm Invasiveness; Odds Ratio; Papillomaviridae; Papillomavirus Infections; Regression Analysis; Risk Factors; Tumor Virus Infections; United States; Uterine Cervical Neoplasms

2001
Serum folate and homocysteine levels in head and neck squamous cell carcinoma.
    Cancer, 2002, Feb-15, Volume: 94, Issue:4

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Progression; Female; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Smoking

2002
[Blood and urinary methotrexate determinations in patients with squamous cell carcinoma of the head and neck area].
    Nederlands tijdschrift voor geneeskunde, 1979, Jan-13, Volume: 123, Issue:2

    Topics: Carcinoma, Squamous Cell; Clinical Enzyme Tests; Drug Therapy, Combination; Folic Acid; Head and Neck Neoplasms; Humans; Methotrexate; Radioimmunoassay

1979
In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
    International journal of cancer, 1992, Jul-30, Volume: 51, Issue:6

    Topics: Aminopterin; Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tumor Cells, Cultured

1992
A case-control study of nutrient status and invasive cervical cancer. I. Dietary indicators.
    American journal of epidemiology, 1991, Dec-01, Volume: 134, Issue:11

    Topics: Ascorbic Acid; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Female; Folic Acid; Humans; Latin America; Neoplasm Invasiveness; Nutritional Status; Risk Factors; Uterine Cervical Neoplasms; Vitamin A

1991
A case-control study of serum folate levels and invasive cervical cancer.
    Cancer research, 1991, Sep-15, Volume: 51, Issue:18

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Case-Control Studies; Contraceptives, Oral; Female; Folic Acid; Humans; Middle Aged; Parity; Pregnancy; Risk Factors; South America; Uterine Cervical Neoplasms

1991
Effect of intracellular folate concentration on the modulation of 5-fluorouracil cytotoxicity by the elevation of phosphoribosylpyrophosphate in cultured human KB cells.
    Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1

    Topics: Adenosine; Carcinoma, Squamous Cell; Cell Survival; Fluorouracil; Folic Acid; Glucose; Humans; KB Cells; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Nasopharyngeal Neoplasms; Pentosephosphates; Phosphoribosyl Pyrophosphate; Thymidine

1987
A comparison of dihydrofolate reductase activity in intact leukemia cells and squamous cell carcinoma.
    Anti-cancer drug design, 1989, Volume: 4, Issue:1

    Topics: Animals; Biological Transport; Carcinoma, Squamous Cell; Cell Count; DNA, Neoplasm; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Leukemia L1210; Methotrexate; Oxidation-Reduction; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured

1989
Influence on immunoreactive folate-binding proteins of extracellular folate concentration in cultured human cells.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:5

    Topics: Animals; Breast Neoplasms; Carcinoma, Squamous Cell; Carrier Proteins; Cell Line; Cells, Cultured; Culture Media; Fibroblasts; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lymphocytes; Mammary Neoplasms, Experimental; Nasopharyngeal Neoplasms; Radioimmunoassay; Receptors, Cell Surface; Tumor Cells, Cultured

1988
Accelerated split-course radiotherapy and simultaneous cis-dichlorodiammine-platinum and 5-fluorouracil chemotherapy with folinic acid enhancement for unresectable carcinoma of the head and neck.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1987, Volume: 10, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Gamma Rays; Head and Neck Neoplasms; Humans; Male; Middle Aged; Radiotherapy Planning, Computer-Assisted

1987
The influence of extracellular folate concentration on methotrexate uptake by human KB cells. Partial characterization of a membrane-associated methotrexate binding protein.
    The Journal of biological chemistry, 1986, Jan-05, Volume: 261, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Carrier Proteins; Cell Division; Chickens; Chromatography, Gel; Chromatography, High Pressure Liquid; Cross Reactions; Culture Media; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Methotrexate; Molecular Weight; Octoxynol; Polyethylene Glycols; Receptors, Cell Surface; Solubility; Subcellular Fractions; Tetrahydrofolate Dehydrogenase; Tissue Distribution

1986
Studies of the role of a particulate folate-binding protein in the uptake of 5-methyltetrahydrofolate by cultured human KB cells.
    The Journal of biological chemistry, 1985, Dec-05, Volume: 260, Issue:28

    Topics: Carcinoma, Squamous Cell; Carrier Proteins; Cell Line; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Molecular Weight; Receptors, Cell Surface; Temperature; Tetrahydrofolates; Time Factors; Trypsin

1985
[Bronchial epidermoid cancer with normochromic megaloblastic anemia caused by folic acid deficiency].
    Journal francais de medecine et chirurgie thoraciques, 1969, Volume: 23, Issue:1

    Topics: Administration, Oral; Aged; Anemia, Macrocytic; Bronchial Neoplasms; Carcinoma, Squamous Cell; Folic Acid; Folic Acid Deficiency; Humans; Injections, Intramuscular; Male; Vitamin B 12

1969
Sequential chemotherapy and radiation therapy of buccal mucosa carcinoma in South India. Methods and preliminary results.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1968, Volume: 102, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cheek; Cobalt Isotopes; Deoxyuridine; Female; Fluorouracil; Folic Acid; Humans; India; Leukocyte Count; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage

1968