folic acid has been researched along with Carcinoma, Epidermoid in 97 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (12.37) | 18.7374 |
1990's | 8 (8.25) | 18.2507 |
2000's | 26 (26.80) | 29.6817 |
2010's | 42 (43.30) | 24.3611 |
2020's | 9 (9.28) | 2.80 |
Authors | Studies |
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Antonsson, A; Green, AC; Hughes, MCB; Liyanage, UE; Rodriguez-Acevedo, AJ; van der Pols, JC | 1 |
Cao, M; Chen, X; He, M; Li, X; Liu, Y; Zhang, X; Zhao, J; Zhao, Q | 1 |
Chen, Y; Li, S; Li, X; Yin, D; Yin, Y | 1 |
Creeden, JF; Hamouda, D; Lin, L; Nemunaitis, J; Ngo, N; Stanbery, L; Young, O | 1 |
Azari, F; Bou-Samra, P; Chang, A; Delikatny, E; Din, A; Doraid, J; Galandarova, A; Ibrahimli, A; Karimov, Z; Kennedy, G; Kucharczuk, J; Nadeem, B; Pechet, T; Singhal, S; Zhang, K | 1 |
Ansari, A; Banerjee, R; Bhattacharya, D; Dhiman, C; Kundu, TK; Narayan, KP; Sakhare, K | 1 |
Can, O; Gok, O; Guner, R; Sahsuvar, S | 1 |
Chen, J; Chen, L; Fan, L; Pu, Y; Wang, J; Wang, Y; Xia, C; Zhang, Q | 1 |
Bharadwaj, R; Medhi, S | 1 |
Xu, L; Yang, H; Yeudall, WA | 1 |
Kairdolf, BA; Lane, LA; Lee, GY; Lu, Q; Nie, S; Peng, X; Wang, J; Wang, Y; Wu, J; Wu, S | 1 |
Abnet, CC; Albanes, D; Freedman, ND; Männistö, S; Miranti, EH; Murphy, G; Selhub, J; Stolzenberg-Solomon, R; Taylor, PR; Weinstein, SJ | 1 |
Cheng, Z; Ding, X; Fan, C; Su, J; Yu, S; Zhang, S | 1 |
Chen, LQ; Hu, WP; Shang, QX; Yang, YS; Yuan, Y | 1 |
Cuadros, K; Goral, J; Green, JM; Guimaraes, EP; Hanemann, JAC; Jham, BC; Meyer, A; Pitstick, L | 1 |
Hazekawa, M; Kawakubo-Yasukochi, T; Morioka, M; Nakamura, S; Nakashima, M; Nishinakagawa, T; Ohe, K; Ono, K; Ozaki, Y; Yasukochi, A | 1 |
Chen, XY; Wen, YY; Yang, SJ; Zhang, JX | 1 |
Allen, TC | 1 |
Ding, L; Hao, J; Jiang, SW; Wang, JT; Yang, ZK; Zhang, L; Zhao, WM; Zhou, Q | 1 |
Cai, HZ; Huang, GL; Su, M; Sun, GJ; Wang, SK; Wang, TT; Yin, H | 1 |
Abnet, CC; Freedman, ND; Hollenbeck, AR; Park, Y; Ren, J; Xiao, Q | 1 |
Lu, M; Ma, X; Xiang, G; Yang, G; Yang, T; Zhang, W | 1 |
Apollo, A; Cox, L; Fury, MG; Haque, S; Ho, AL; Lipson, BL; Lyo, JK; Pfister, DG; Sales, R; Seetharamu, N; Sherman, EJ; Sima, CS; Xiao, H | 1 |
Chen, DP; Li, MY; Liang, YY; Liu, JQ; Qi, B; Yin, WJ | 1 |
Bai, LX; Chen, C; Chen, X; Ding, L; Gao, CF; Jiang, SW; Kang, HJ; Wang, JT; Zhou, Q | 1 |
Bai, L; Chen, X; Ding, L; Sun, X; Wang, J; Wu, T; Xu, J | 1 |
Bazi, A; Garme, Y; Khosravi, A; Miri-Moghaddam, E; Motazedian, J; Saravani, S | 1 |
Moghanaki, AA; Pourjavadi, A; Tehrani, ZM | 1 |
Chen, F; Ding, L; Li, QL; Liang, YL; Liu, CL; Nan, J; Wang, JT; Yang, ZK | 1 |
Abnet, CC; Dawsey, SM; Fan, J; Murphy, G; Qiao, Y; Ren, J; Selhub, J; Taylor, PR | 1 |
Guan, S; Li, C; Liang, R; Wei, M | 1 |
Bossi, P; Licitra, L; Locati, LD; Tagliabue, E | 1 |
Chen, Z; Cho, K; Müller, S; Nie, S; Saba, NF; Shin, DM; Tighiouart, M; Wang, X | 1 |
Fulmer, AK; Mauldin, GE; Mauldin, GN | 1 |
Baker, JR; Dimaggio, S; Holl, MM; Hong, S; Kelly, C; Kotlyar, A; Landmark, KJ; Myc, A; Orr, BG; Penner-Hahn, JE; Thomas, TP; Vogt, S; Ward, J | 1 |
Arpicco, S; Brusa, P; Cattel, L; Dosio, F; Stella, B | 1 |
Fukui, Y; Jin, M; Kawakami, K; Minamoto, T; Oda, M; Oka, T; Takechi, T; Tsukioka, S; Watanabe, G | 1 |
Barata, F; Barlesi, F; Bearz, A; Bepler, G; Chiappori, A; Chouaki, N; Iscoe, N; Liepa, AM; Park, K; Reck, M; Scagliotti, G; Soria, JC; von Pawel, J; Wagle, A; Zhao, YD | 1 |
Ghannoum, JE; Odingo, NA; Provost, N | 1 |
Allen, N; Altzibar, JM; Barricarte, A; Benetou, V; Boeing, H; Bosch, FX; Boutron-Ruault, MC; Bueno-de-Mesquita, HB; Castellsagué, X; Clavel-Chapelon, F; Dillner, J; Engeset, D; Franceschi, S; González, CA; Hallmans, G; Kaaks, R; Key, TJ; Kjaer, SK; Kjellberg, L; Luján-Barroso, L; Lund, E; Manjer, J; Munk, C; Naska, A; Navarro, C; Olsen, A; Overvad, K; Pala, V; Palli, D; Panico, S; Peeters, PH; Riboli, E; Rinaldi, S; Rodriguez, L; Rohrmann, S; Roura, E; Sacerdote, C; Sanchez, MJ; Skeie, G; Slimani, N; Tjønneland, A; Travier, N; Trichopoulou, A; Tumino, R; van Duijnhoven, FJ | 1 |
Green, AC; Hayward, N; Hughes, MC; Ibiebele, TI; Montgomery, G; Pandeya, N; Webb, PM; Whiteman, DC; Zhao, Z | 1 |
Akbas, Y; Beyazit, Y; Gorgulu, O; Ozdemir, S; Sayar, C; Selcuk, T | 1 |
Lu, C; Shen, H; Wang, F; Wang, J; Xie, H | 1 |
Hanai, N; Hasegawa, Y; Hosono, S; Ito, H; Kawakita, D; Matsuo, K; Murakami, S; Oze, I; Sato, F; Tajima, K; Tanaka, H; Watanabe, M; Yatabe, Y | 1 |
Ghosh, PC; Tyagi, N | 1 |
da Silva, LM; Galbiatti, AL; Goloni-Bertollo, EM; Maniglia, JV; Pavarino, EC; Raposo, LS; Ruiz, MT | 1 |
Ding, L; Fan, JR; Hao, M; Huo, XX; Wang, JT; Zhang, L; Zhao, WM | 1 |
Azzoli, CG; Dunne, M; Ginsberg, M; Huntington, M; James, L; Kris, MG; Krug, LM; May, J; Miller, V; Patel, JD; Saunders, M; Sirotnak, FM; Subzwari, S; Tyson, L | 1 |
Hasegawa, Y; Hosono, S; Ito, H; La Vecchia, C; Matsuo, K; Negri, E; Oze, I; Rossi, M; Tajima, K; Tanaka, H; Watanabe, M; Yatabe, Y | 1 |
da Silva, LM; Galbiatti, AL; Goloni-Bertollo, EM; Maníglia, JV; Pavarino, EC; Raposo, LS; Ruiz-Cintra, MT | 1 |
Asomaning, K; Christiani, DC; Lee, MS; Mark, EJ; Su, L; Wain, JC | 1 |
Gotay, C; Hajizadeh, B; Jessri, M; Rashidkhani, B | 1 |
Duarte, S; Faneca, H; Lima, MC | 1 |
Bergman, CJ; Chang, S; Hajibandeh, J; Keiserman, MA; Kingsley, K; McCabe, J; Meeder, CA; Moody, M; Nguyen, DH; Sharma, K; Tran, MD | 1 |
Duan, Y; Huang, Z; Jiang, J; Jing, C; Xiao, X; Zhang, R | 1 |
Cagle, PT; Low, PS; Murphy, L; Zhai, QJ | 1 |
Chen, J; Duan, YQ; Huang, ZJ; Jiang, JQ; Xiao, XR; Zhang, R | 1 |
Ding, L; Hao, JX; Hao, M; Wang, JT; Zhao, WM; Zhou, Q | 1 |
Bollschweiler, E; Hölscher, AH; Mönig, SP; Nowroth, T; Rosendahl, U; Wolfgarten, E | 1 |
Frick, B; Fuchs, D; Schröcksnadel, K | 1 |
Lee, RJ; Pan, XQ; Wang, H | 1 |
Bavetsias, V; Gibbs, D; Jackman, AL; Jansen, G; Skelton, LA; Theti, DS; Titley, J | 1 |
CONDIT, PT; OWENS, AH; SHNIDER, BI | 1 |
BERTINO, JR; HELLMAN, S; IANNOTTI, AT | 1 |
DELLER, DJ; WANGEL, AG | 1 |
Almadori, G; Bussu, F; Cadoni, G; Galli, J; Giardina, B; Maurizi, M; Minucci, A; Persichilli, S; Zappacosta, B | 1 |
Kane, MA | 1 |
Franceschi, S; Galeone, C; La Vecchia, C; Levi, F; Negri, E; Pelucchi, C; Talamini, R | 1 |
Brown, KS; Kane, MA | 1 |
Hsiung, D; Kelsey, KT; Kraunz, KS; Liu, M; McClean, MD; Nelson, HH; Osanyingbemi, J | 1 |
Giovannucci, E; Larsson, SC; Wolk, A | 1 |
Hida, T; Hiraki, A; Matsuo, K; Mitsudomi, T; Saito, T; Sato, S; Suzuki, T; Tajima, K; Ueda, R; Yatabe, Y | 1 |
Hasegawa, Y; Hiraki, A; Hirose, K; Matsuo, K; Saito, T; Sato, S; Suzuki, T; Tajima, K; Ueda, R; Wakai, K | 1 |
Chayama, K; Hiyama, T; Tanaka, S; Yoshihara, M | 1 |
Baker, JA; Brasure, JR; Ghosh, C; McCann, SE; Moysich, KB; Rivera, R | 1 |
Kamen, BA; Kreisler, AR; Orr, RB | 1 |
Kamen, BA; Orr, RB | 2 |
Capizzi, RL; George, T; Kamen, BA; McGuirt, F; Schifeling, DJ | 1 |
Faessel, HM; Greco, WR; Rustum, YM; Slocum, HK | 1 |
Michael, CW; Reynolds, RK; Rock, CL; Ruffin, MT | 1 |
Backus, HH; Jansen, G; Molders, N; Padrón, JM; Peters, GJ; Pinedo, HM; van Der Wilt, CL; van Groeningen, CJ; Wouters, D | 1 |
Grizzle, WE; Heimburger, DC; Johanning, GL; Macaluso, M; Oelschlager, DK; Piyathilake, CJ; Whiteside, M | 1 |
Bisogni, CA; Brinton, LA; Colman, N; Frongillo, EA; Hamman, RF; Levine, RS; Mallin, K; Sauberlich, HE; Stolley, PD; Weinstein, SJ; Ziegler, RG | 1 |
Almadori, G; Bussu, F; Cadoni, G; Galli, J; Giardina, B; Minucci, A; Persichilli, S; Zappacosta, B | 1 |
Snow, GB; van der Vijgh, WJ; Versluis, RJ | 1 |
Hordijk, GJ; Jansen, G; Kathmann, GA; Schornagel, JH; van der Laan, BF; Westerhof, GR | 1 |
Brenes, MM; Brinton, LA; de Britton, RC; Gaitan, E; Herrero, R; Potischman, N; Reeves, WC; Tenorio, F | 1 |
Brenes, MM; Brinton, LA; de Britton, RC; Gaitan, E; Herrero, R; Laiming, VA; Potischman, N; Reeves, WC; Tenorio, F | 1 |
Kane, MA; Raptis, G; Roth, E; Schreiber, C; Waxman, S | 1 |
FitzGerald, GB; Wick, MM | 1 |
Antony, AC; Elwood, PC; Finley, A; Kane, MA; Kolhouse, JF; Najfeld, V; Portillo, RM; Waxman, S | 1 |
Hartenstein, RC; Rohloff, R; Trott, KR; Wendt, TG; Wustrow, TP | 1 |
Antony, AC; Elwood, PC; Kane, MA; Kolhouse, JF; Portillo, RM | 2 |
Battesti, JP; Turiaf, J | 1 |
Joseph, LB; Simon, GT; Singh, AD; Singh, SP; Von Essen, CF | 1 |
8 review(s) available for folic acid and Carcinoma, Epidermoid
Article | Year |
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Folate Receptor as a Biomarker and Therapeutic Target in Solid Tumors.
Topics: Biomarkers; Carcinoma, Squamous Cell; Folic Acid; Folic Acid Antagonists; Humans; Prognosis | 2023 |
Association between folate intake and risk of head and neck squamous cell carcinoma: An overall and dose-response PRISMA meta-analysis.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Diet; Dose-Response Relationship, Drug; Eating; Female; Folic Acid; Folic Acid Deficiency; Head and Neck Neoplasms; Humans; Male; Middle Aged; Observational Studies as Topic; Odds Ratio; Risk Factors; Squamous Cell Carcinoma of Head and Neck | 2017 |
Methylenetetrahydrofolate reductase genetic polymorphisms and esophageal squamous cell carcinoma susceptibility: a meta-analysis of case-control studies.
Topics: Carcinoma, Squamous Cell; Case-Control Studies; Confidence Intervals; Diet; Esophageal Neoplasms; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors | 2013 |
The role of folates in squamous cell carcinoma of the head and neck.
Topics: Alcohol Drinking; Carcinoma, Squamous Cell; Chemoprevention; Folic Acid; Folic Acid Deficiency; Head and Neck Neoplasms; Humans; Risk Factors; Smoking | 2005 |
Chemoprevention of squamous cell carcinoma of the oral cavity.
Topics: Antineoplastic Agents; Ascorbic Acid; Carcinoma, Squamous Cell; Drugs, Chinese Herbal; Flavonoids; Folic Acid; Humans; Mouth Neoplasms; Precancerous Conditions; Retinoids; Selenium; Vitamin A; Vitamin E | 2006 |
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Case-Control Studies; Esophageal Neoplasms; Folic Acid; Gastrointestinal Neoplasms; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Pancreatic Neoplasms; Polymorphism, Genetic; Risk Factors; Stomach Neoplasms | 2006 |
Genetic polymorphisms and esophageal cancer risk.
Topics: Adenocarcinoma; Alcohol Oxidoreductases; Carcinoma, Squamous Cell; Cytochrome P-450 Enzyme System; DNA Repair; Esophageal Neoplasms; Folic Acid; Genes, cdc; Genetic Predisposition to Disease; Humans; Meta-Analysis as Topic; Odds Ratio; Oncogenes; Polymorphism, Genetic; Risk Factors | 2007 |
Prevention of cervix cancer.
Topics: Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; beta Carotene; Carcinoma, Squamous Cell; Clinical Trials as Topic; Colposcopy; Diet; Female; Folic Acid; Humans; Image Processing, Computer-Assisted; Mass Screening; Nutritional Requirements; Papanicolaou Test; Papillomaviridae; Papillomavirus Infections; Photochemotherapy; Risk Factors; Tumor Virus Infections; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Vaginal Smears; Viral Vaccines; Vitamin E; Vitamins | 2000 |
6 trial(s) available for folic acid and Carcinoma, Epidermoid
Article | Year |
---|---|
Low vitamin B
Topics: Aged; alpha-Tocopherol; beta Carotene; Carcinoma, Squamous Cell; Case-Control Studies; Dietary Supplements; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Finland; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Riboflavin; Stomach Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2017 |
A phase II study of pralatrexate with vitamin B12 and folic acid supplementation for previously treated recurrent and/or metastatic head and neck squamous cell cancer.
Topics: Adult; Aged; Aminopterin; Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck; Vitamin B 12; Vitamin B Complex; Young Adult | 2014 |
Glycididazole sodium combined with radiochemotherapy for locally advanced nasopharyngeal carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Case-Control Studies; Chemoradiotherapy; Cisplatin; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Humans; Male; Metronidazole; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Staging; Prognosis; Survival Rate | 2014 |
Phase II, double-blinded, randomized study of enzastaurin plus pemetrexed as second-line therapy in patients with advanced non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Double-Blind Method; Female; Folic Acid; Glutamates; Guanine; Humans; Indoles; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Pemetrexed; Prognosis; Salvage Therapy; Survival Rate; Vitamin B 12 | 2010 |
Pralatrexate with vitamin supplementation in patients with previously treated, advanced non-small cell lung cancer: safety and efficacy in a phase 1 trial.
Topics: Adenocarcinoma; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Tissue Distribution; Vitamin B 12; Vitamin B Complex | 2011 |
Vitamin intake and risk of subtypes of esophageal cancer in Germany.
Topics: Adenocarcinoma; Adult; Alcohol Drinking; Ascorbic Acid; Body Mass Index; Carcinoma, Squamous Cell; Case-Control Studies; Dietary Supplements; Esophageal Neoplasms; Folic Acid; Germany; Humans; Incidence; Male; Pilot Projects; Risk Factors; Smoking; Surveys and Questionnaires; Vitamin A; Vitamin E | 2002 |
83 other study(ies) available for folic acid and Carcinoma, Epidermoid
Article | Year |
---|---|
Dark Green Leafy Vegetable Intake, MTHFR Genotype, and Risk of Cutaneous Squamous Cell Carcinoma.
Topics: Australia; Carcinoma, Squamous Cell; Case-Control Studies; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Longitudinal Studies; Methylenetetrahydrofolate Reductase (NADPH2); Risk Factors; Skin Neoplasms; Vegetables | 2022 |
Folate Receptor 4-Expressing T cell Is Associated with Disease-Free Survival in Patients with Esophageal Squamous Cell Carcinoma.
Topics: Carcinoma, Squamous Cell; Disease-Free Survival; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Folic Acid; Humans; Prognosis; Retrospective Studies | 2022 |
Dietary habits, nutrition and esophageal cancer: A case-control study on Kazakhs in Xinjiang.
Topics: Carcinoma, Squamous Cell; Case-Control Studies; Esophageal Neoplasms; Feeding Behavior; Folic Acid; Humans; Nutritional Status; Risk Factors | 2022 |
Prospective validation of tumor folate receptor expression density with the association of pafolacianine fluorescence during intraoperative molecular imaging-guided lung cancer resections.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Folic Acid; Humans; Lung Neoplasms; Molecular Imaging; Prospective Studies | 2023 |
Delivery of chemotherapeutic drug targeting folate receptor to oral cancer cells using functionalized carbon nanospheres.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Folic Acid; Ligands; Mice; Mouth Neoplasms; Nanospheres | 2023 |
Development and pharmaceutical investigation of novel cervical cancer-targeting and redox-responsive melittin conjugates.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Female; Folic Acid; HeLa Cells; Humans; Melitten; Oxidation-Reduction; Pharmaceutical Preparations; Uterine Cervical Neoplasms | 2023 |
Glutathione-sensitive and folate-targeted nanoparticles loaded with paclitaxel to enhance oral squamous cell carcinoma therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Proliferation; Drug Liberation; Drug Screening Assays, Antitumor; Folic Acid; Glutathione; Humans; Male; Mice; Mice, Inbred BALB C; Mouth Neoplasms; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Particle Size; Surface Properties; Tumor Cells, Cultured | 2020 |
Effectual nanotherapy against oral squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Carriers; Folic Acid; Head and Neck Neoplasms; Mouth Neoplasms; Nanoparticles; Paclitaxel; Squamous Cell Carcinoma of Head and Neck; Tissue Distribution | 2021 |
Folic acid-decorated polyamidoamine dendrimer exhibits high tumor uptake and sustained highly localized retention in solid tumors: Its utility for local siRNA delivery.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Dendrimers; Female; Folic Acid; Gene Transfer Techniques; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Proteins; Neovascularization, Pathologic; Polyamines; RNA, Small Interfering; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2017 |
Quantitative Examination of the Active Targeting Effect: The Key Factor for Maximal Tumor Accumulation and Retention of Short-Circulated Biopolymeric Nanocarriers.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Drug Carriers; Drug Delivery Systems; Folic Acid; Heparin; Humans; Mice; Mice, Nude; Nanoparticles; Polymers; Tissue Distribution | 2017 |
The role of mitochondrial folate enzyme MTHFD1L in esophageal squamous cell carcinoma.
Topics: Aged; Aged, 80 and over; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Minor Histocompatibility Antigens; Mitochondria; Quality of Life; RNA, Small Interfering | 2018 |
Decreased expression of folate transport proteins in oral cancer.
Topics: Carcinoma, Squamous Cell; Folic Acid; Folic Acid Antagonists; Folic Acid Transporters; Humans; Mouth Neoplasms; Reduced Folate Carrier Protein | 2019 |
Maternal folic acid depletion during early pregnancy increases sensitivity to squamous tumor formation in the offspring in mice.
Topics: Animals; Animals, Newborn; Carcinoma, Squamous Cell; Female; Folic Acid; Folic Acid Deficiency; Male; Maternal Nutritional Physiological Phenomena; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Skin Neoplasms; Tongue Neoplasms | 2019 |
Targeted molecular therapy for lung cancer: exuberance reestablished.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation, Preclinical; Female; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms; Male; Neoplasms | 2013 |
Folate deficiency and aberrant expression of DNA methyltransferase 1 were associated with cervical cancerization.
Topics: Adult; Aged; Carcinoma, Squamous Cell; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; RNA, Messenger; Severity of Illness Index; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2014 |
Serum folate, MTHFR C677T polymorphism and esophageal squamous cell carcinoma risk.
Topics: Carcinoma, Squamous Cell; Chi-Square Distribution; Esophageal Neoplasms; Folic Acid; Genetic Predisposition to Disease; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic | 2013 |
Intakes of folate, methionine, vitamin B6, and vitamin B12 with risk of esophageal and gastric cancer in a large cohort study.
Topics: Carcinoma, Squamous Cell; Cohort Studies; Diet; Esophageal Neoplasms; Female; Folic Acid; Humans; Male; Methionine; Middle Aged; Risk; Stomach Neoplasms; United States; Vitamin B 12; Vitamin B 6 | 2014 |
In vitro and in vivo antitumor effects of folate-targeted ursolic acid stealth liposome.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Area Under Curve; Biological Availability; Carcinoma, Squamous Cell; Cholesterol Esters; Drug Delivery Systems; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Liposomes; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Mouth Neoplasms; Polyethylene Glycols; Solubility; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2014 |
Folate deficiency and FHIT hypermethylation and HPV 16 infection promote cervical cancerization.
Topics: Acid Anhydride Hydrolases; Adult; Carcinoma, Squamous Cell; Cohort Studies; CpG Islands; Disease Progression; DNA Methylation; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Human papillomavirus 16; Humans; Middle Aged; Neoplasm Proteins; Papillomavirus Infections; Polymerase Chain Reaction; Sensitivity and Specificity; Uterine Cervical Neoplasms | 2014 |
[Interaction between folate deficiency and aberrant expression related to fragile histidine triad gene in the progression of cervical cancerization].
Topics: Acid Anhydride Hydrolases; Apoptosis; Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Deficiency; Human papillomavirus 16; Humans; Neoplasm Proteins; Polymerase Chain Reaction; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2015 |
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms in oral squamous cell carcinoma in south-east Iran.
Topics: Adult; Aged; Alleles; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; Head and Neck Neoplasms; Humans; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mouth Neoplasms; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Factors; Squamous Cell Carcinoma of Head and Neck | 2016 |
Folate-Conjugated pH-Responsive Nanocarrier Designed for Active Tumor Targeting and Controlled Release of Gemcitabine.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Delayed-Action Preparations; Deoxycytidine; Drug Delivery Systems; Folic Acid; Gemcitabine; Graphite; Humans; Hydrogen-Ion Concentration; Nanoparticles; Polyethylene Glycols; Silicon Dioxide | 2016 |
[Relationship and interaction between folate and expression of methyl-CpG-binding protein 2 in cervical cancerization].
Topics: Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Deficiency; Humans; Methyl-CpG-Binding Protein 2; Polymerase Chain Reaction; RNA, Messenger; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2016 |
Prospective study of serum B vitamins levels and oesophageal and gastric cancers in China.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Cardia; China; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Flavin Mononucleotide; Folic Acid; Humans; Male; Middle Aged; Niacin; Proportional Hazards Models; Prospective Studies; Pyridoxal Phosphate; Riboflavin; Stomach Neoplasms; Vitamin B 12; Vitamin B Complex | 2016 |
A supramolecular material for dual-modal imaging and targeted cancer therapy.
Topics: Carcinoma, Squamous Cell; Cell Survival; Dextrans; Doxorubicin; Fluorescein-5-isothiocyanate; Folic Acid; Gadolinium; Humans; Hydroxides; Intercalating Agents; Magnetic Resonance Imaging; Optical Imaging; Tumor Cells, Cultured | 2017 |
Folate in head and neck squamous cell cancer chemoprevention: purposely left out?
Topics: Carcinoma, Squamous Cell; Chemoprevention; Folic Acid; Folic Acid Deficiency; Head and Neck Neoplasms; Humans; Risk Assessment; Sensitivity and Specificity | 2008 |
Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lymphatic Metastasis; Male; Middle Aged; Nanomedicine; Nanotechnology; Paclitaxel; Receptors, Cell Surface; Young Adult | 2009 |
Evaluation of plasma folate and homocysteine concentrations in cats with and without oral squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cat Diseases; Cats; Female; Folic Acid; Homocysteine; Male; Mouth Neoplasms | 2008 |
Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Contrast Media; Crystallization; Drug Carriers; Ferric Compounds; Folic Acid; Humans; Macromolecular Substances; Magnetic Resonance Imaging; Magnetics; Materials Testing; Molecular Conformation; Nanomedicine; Nanostructures; Particle Size; Surface Properties | 2008 |
Folate-mediated targeting of albumin conjugates of paclitaxel obtained through a heterogeneous phase system.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Carrier Proteins; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Chromatography, Gel; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Folate Receptors, GPI-Anchored; Folic Acid; HT29 Cells; Humans; Inhibitory Concentration 50; KB Cells; Nasopharyngeal Neoplasms; Paclitaxel; Polyethylene Glycols; Receptors, Cell Surface; Serum Albumin; Solubility; Technology, Pharmaceutical; Triazines | 2009 |
Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Cadherins; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Core Binding Factor Alpha 3 Subunit; DNA Methylation; Female; Folic Acid; Humans; Immunohistochemistry; Long Interspersed Nucleotide Elements; Lung Neoplasms; Male; Middle Aged | 2009 |
Clinico-pathologic conference: case 6.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell; Carpal Tunnel Syndrome; Clonidine; Dermatomyositis; Diabetes Mellitus, Type 1; Diagnosis, Differential; Edema; Exanthema; Face; Female; Folic Acid; Hematinics; Humans; Hypertension; Hypoglycemic Agents; Hypothyroidism; Insulin; Lupus Erythematosus, Discoid; Middle Aged; Neoplasms, Unknown Primary; Paraneoplastic Syndromes; Radiotherapy, Intensity-Modulated; Skin Neoplasms; Thyroxine | 2009 |
Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study.
Topics: Adult; Aged; Ascorbic Acid; beta Carotene; Carcinoma; Carcinoma, Squamous Cell; Diet; Europe; Female; Folic Acid; Follow-Up Studies; Fruit; Humans; Middle Aged; Neoplasm Invasiveness; Nutrition Surveys; Prospective Studies; Risk Factors; Uterine Cervical Neoplasms; Vegetables; Vitamin A; Vitamin D; Vitamin E | 2011 |
High intake of folate from food sources is associated with reduced risk of esophageal cancer in an Australian population.
Topics: Adenocarcinoma; Adult; Aged; Alcohol Drinking; Australia; Barrett Esophagus; Betaine; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Dietary Supplements; Esophageal Neoplasms; Esophagus; Female; Folic Acid; Humans; Logistic Models; Male; Methionine; Middle Aged; Risk Factors; Smoking; Vitamin B Complex | 2011 |
Evaluation of the roles of serum vitamin B(12), folate and homocysteine levels in laryngeal squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Case-Control Studies; Demography; Folic Acid; Homocysteine; Humans; Laryngeal Neoplasms; Middle Aged; Vitamin B 12 | 2010 |
Diet folate, DNA methylation and genetic polymorphisms of MTHFR C677T in association with the prognosis of esophageal squamous cell carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Aged; Carcinoma, Squamous Cell; Diet; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Eating; Esophageal Neoplasms; Female; Folic Acid; Genes, p16; Genetic Association Studies; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; MutL Protein Homolog 1; Nuclear Proteins; Polymorphism, Single Nucleotide; Prognosis; Tumor Suppressor Proteins | 2011 |
Association between dietary folate intake and clinical outcome in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cohort Studies; Diet; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Minor Histocompatibility Antigens; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Surveys and Questionnaires; Thymidylate Synthase; Young Adult | 2012 |
Folate receptor mediated targeted delivery of ricin entrapped into sterically stabilized liposomes to human epidermoid carcinoma (KB) cells: effect of monensin intercalated into folate-tagged liposomes.
Topics: Animals; Carcinoma, Squamous Cell; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Folic Acid; Folic Acid Transporters; Humans; Intercalating Agents; Liposomes; Monensin; Phosphatidylethanolamines; Polyethylene Glycols; Ricin | 2011 |
MTHFD1 G1958A, BHMT G742A, TC2 C776G and TC2 A67G polymorphisms and head and neck squamous cell carcinoma risk.
Topics: Betaine-Homocysteine S-Methyltransferase; Brazil; Carcinoma, Squamous Cell; DNA Methylation; Female; Folic Acid; Genomic Instability; Head and Neck Neoplasms; Humans; Logistic Models; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Transcobalamins | 2012 |
[Effect of folic acid and DNA methyltransferase 1 on cervical cancer and its precancerous lesion].
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Folic Acid; Humans; Middle Aged; Precancerous Conditions; Uterine Cervical Neoplasms | 2011 |
Folate, alcohol, and aldehyde dehydrogenase 2 polymorphism and the risk of oral and pharyngeal cancer in Japanese.
Topics: Adult; Aged; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Asian People; Carcinoma; Carcinoma, Squamous Cell; Case-Control Studies; Eating; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms; Polymorphism, Single Nucleotide; Risk Factors; Squamous Cell Carcinoma of Head and Neck; Young Adult | 2012 |
Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk.
Topics: Aged; Alleles; Carcinoma, Squamous Cell; Case-Control Studies; DNA Methylation; Female; Folic Acid; Gene Deletion; Genotype; Head and Neck Neoplasms; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Statistical; Polymorphism, Genetic; Regression Analysis; Risk; Squamous Cell Carcinoma of Head and Neck; Time Factors; Treatment Outcome | 2012 |
MTHFR polymorphisms, folate intake and carcinogen DNA adducts in the lung.
Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Case-Control Studies; DNA Adducts; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Lung; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Staging; Polymorphism, Genetic; Prognosis; Risk Factors; Smoking | 2012 |
Macronutrients, vitamins and minerals intake and risk of esophageal squamous cell carcinoma: a case-control study in Iran.
Topics: Aged; alpha-Tocopherol; beta Carotene; Carcinoma, Squamous Cell; Case-Control Studies; Confidence Intervals; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Energy Intake; Esophageal Neoplasms; Feeding Behavior; Female; Folic Acid; Hospitalization; Humans; Incidence; Interviews as Topic; Iran; Logistic Models; Male; Micronutrients; Middle Aged; Odds Ratio; Pilot Projects; Risk Factors; Selenium; Surveys and Questionnaires; Vitamin E; Vitamins | 2011 |
Folate-associated lipoplexes mediate efficient gene delivery and potent antitumoral activity in vitro and in vivo.
Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Survival; Cholesterol; Connexin 43; DNA; Female; Folate Receptors, GPI-Anchored; Folic Acid; Genes, Reporter; Genes, Transgenic, Suicide; Genetic Therapy; Mice; Mice, Inbred C3H; Mouth Neoplasms; Phosphatidylcholines; Thymidine Kinase; Time Factors; Transfection; Viral Proteins | 2012 |
Folate supplementation induces differential dose-dependent modulation of proliferative phenotypes among cancerous and noncancerous oral cell lines in vitro.
Topics: Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Dose-Response Relationship, Drug; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mouth Neoplasms; Phenotype; Polymorphism, Genetic; RNA, Messenger; Tumor Suppressor Protein p53; Vitamin B Complex | 2010 |
Folate intake, methylenetetrahydrofolate reductase polymorphisms in association with the prognosis of esophageal squamous cell carcinoma.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Squamous Cell; China; Cohort Studies; Esophageal Neoplasms; Female; Folic Acid; Follow-Up Studies; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prognosis | 2012 |
Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Folate Receptor 1; Folic Acid; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Tissue Array Analysis | 2013 |
Aberrant DNA methylation of P16, MGMT, and hMLH1 genes in combination with MTHFR C677T genetic polymorphism and folate intake in esophageal squamous cell carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Carcinoma, Squamous Cell; Case-Control Studies; Cyclin-Dependent Kinase Inhibitor p16; DNA; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Esophageal Neoplasms; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; MutL Protein Homolog 1; Neoplasm Proteins; Neoplasm Staging; Nuclear Proteins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prognosis; Risk Factors; Tumor Suppressor Proteins | 2012 |
[Interaction of folate deficiency and aberrant profile of DNA methyltransferase 1 in the progression of cervix carcinogenesis].
Topics: Adult; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Folic Acid; Folic Acid Deficiency; Humans; Middle Aged; RNA, Messenger; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2012 |
Serum folate and homocysteine levels in head and neck squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Disease Progression; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Hyperhomocysteinemia; Neopterin; Prognosis; Risk Factors | 2002 |
Antitumor activity of folate receptor-targeted liposomal doxorubicin in a KB oral carcinoma murine xenograft model.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Carrier Proteins; Doxorubicin; Fluorometry; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Injections, Intraperitoneal; KB Cells; Liposomes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Neoplasm Transplantation; Receptors, Cell Surface; Survival Analysis; Time Factors; Xenograft Model Antitumor Assays | 2003 |
Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the alpha-isoform of the folate receptor.
Topics: Antineoplastic Agents; Biological Transport; Carcinoma, Squamous Cell; Carrier Proteins; Cell Division; Cyclopentanes; Enzyme Inhibitors; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Kinetics; Quinazolines; Receptors, Cell Surface; Recombinant Proteins; Thymidylate Synthase; Transfection; Tumor Cells, Cultured; Vulvar Neoplasms | 2003 |
Studies on the folic acid vitamins. VII. The effects of large doses of amethopterin in patients with cancer.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Folic Acid; Folic Acid Antagonists; Methotrexate; Neomycin; Neoplasms; Vitamins | 1962 |
DETERMINATIONS OF THE LEVELS OF SERUM FOLATE IN PATIENTS WITH CARCINOMA OF THE HEAD AND NECK TREATED WITH METHOTREXATE.
Topics: Blood Chemical Analysis; Carcinoma, Squamous Cell; Folic Acid; Humans; Methotrexate; Nasopharyngeal Neoplasms; Neoplasms; Nose Neoplasms; Osteosarcoma; Pathology; Pharmacology; Pharyngeal Neoplasms; Sarcoma; Tongue Neoplasms | 1964 |
MALABSORPTION SYNDROME ASSOCIATED WITH CARCINOMA OF THE BRONCHUS.
Topics: Anemia; Anemia, Macrocytic; Blood Chemical Analysis; Bronchi; Bronchial Neoplasms; Carcinoma, Squamous Cell; Celiac Disease; Feces; Fluids and Secretions; Folic Acid; Folic Acid Deficiency; Humans; Hypokalemia; Hypoproteinemia; Jejunum; Lipid Metabolism; Malabsorption Syndromes; Pathology; Urine; Vitamin B 12 | 1965 |
Serum levels of folate, homocysteine, and vitamin B12 in head and neck squamous cell carcinoma and in laryngeal leukoplakia.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Laryngeal Neoplasms; Leukoplakia; Male; Middle Aged; Prognosis; Reference Values; Risk Assessment; Sensitivity and Specificity; Vitamin B 12 | 2005 |
Folate intake and squamous-cell carcinoma of the oesophagus in Italian and Swiss men.
Topics: Alcohol Drinking; Carcinoma, Squamous Cell; Case-Control Studies; Esophageal Neoplasms; Folic Acid; Humans; Italy; Male; Methionine; Middle Aged; Switzerland; Vitamin B 6 | 2006 |
Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Diet; DNA Methylation; Female; Folic Acid; Genotype; Head and Neck Neoplasms; Humans; Male; Methylation; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors | 2006 |
Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case control study.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoma, Large Cell; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Japan; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Random Allocation; Risk Factors | 2007 |
One-carbon metabolism-related gene polymorphisms and risk of head and neck squamous cell carcinoma: case-control study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alcohol Drinking; Carbon; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Random Allocation; Risk Factors; Thymidylate Synthase | 2007 |
Dietary intakes of selected nutrients and food groups and risk of cervical cancer.
Topics: Ascorbic Acid; Carcinoma, Squamous Cell; Carotenoids; Case-Control Studies; Confidence Intervals; Diet; Dietary Fiber; Female; Folic Acid; Fruit; Humans; Logistic Models; Menopause; Middle Aged; Odds Ratio; Risk Factors; Surveys and Questionnaires; Uterine Cervical Neoplasms; Vegetables; Vitamin A; Vitamin E | 2008 |
Similarity of folate receptor expression in UMSCC 38 cells to squamous cell carcinoma differentiation markers.
Topics: Antigens, Differentiation; Blotting, Northern; Carcinoma, Squamous Cell; Carrier Proteins; Electrophoresis, Polyacrylamide Gel; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Receptors, Cell Surface; Tretinoin; Tumor Cells, Cultured | 1995 |
Identification of a point mutation in the folate receptor gene that confers a dominant negative phenotype.
Topics: Animals; Carcinoma, Squamous Cell; Carrier Proteins; CHO Cells; Cricetinae; DNA, Complementary; Folate Receptors, GPI-Anchored; Folic Acid; Genes, Dominant; Glycosylphosphatidylinositols; Haplorhini; Humans; Phenotype; Point Mutation; Receptors, Cell Surface; Tetrahydrofolates; Transfection; Tritium | 1995 |
UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor.
Topics: Base Sequence; Biological Transport; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 11; DNA, Complementary; Folate Receptors, GPI-Anchored; Folic Acid; Gene Amplification; Humans; Molecular Sequence Data; Mutation; Receptors, Cell Surface; Tetrahydrofolates; Tumor Cells, Cultured | 1994 |
Methotrexate content in squamous cell carcinoma of the head and neck after low-dose methotrexate.
Topics: Administration, Oral; Adult; Carcinoma, Squamous Cell; Female; Folic Acid; Head and Neck Neoplasms; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Mucous Membrane | 1994 |
Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5,4,6][1,4]thiazin -6-yl)-(S)-ethyl]-2,5-thienoylamino-L-glutamic acid (AG
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Drug Resistance, Multiple; Drug Synergism; Folic Acid; Folic Acid Antagonists; Glutamates; Head and Neck Neoplasms; Humans; Hydroxymethyl and Formyl Transferases; Kinetics; Lung Neoplasms; Phosphoribosylglycinamide Formyltransferase; Pyrimidines; Trimetrexate; Tumor Cells, Cultured | 1999 |
Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Colonic Neoplasms; Fluorouracil; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leucovorin; Lung Neoplasms; Membrane Proteins; Membrane Transport Proteins; Mice; Multienzyme Complexes; Neoplasms; Peptide Synthases; Reduced Folate Carrier Protein; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured | 2000 |
Localized folate and vitamin B-12 deficiency in squamous cell lung cancer is associated with global DNA hypomethylation.
Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; DNA Methylation; Folic Acid; Folic Acid Deficiency; Humans; Lung Neoplasms; Middle Aged; Smoking; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Low serum and red blood cell folate are moderately, but nonsignificantly associated with increased risk of invasive cervical cancer in U.S. women.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Viral; Bacteriological Techniques; Carcinoma, Squamous Cell; Case-Control Studies; Erythrocytes; Female; Folic Acid; Humans; Interviews as Topic; Middle Aged; Neoplasm Invasiveness; Odds Ratio; Papillomaviridae; Papillomavirus Infections; Regression Analysis; Risk Factors; Tumor Virus Infections; United States; Uterine Cervical Neoplasms | 2001 |
Serum folate and homocysteine levels in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Progression; Female; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Smoking | 2002 |
[Blood and urinary methotrexate determinations in patients with squamous cell carcinoma of the head and neck area].
Topics: Carcinoma, Squamous Cell; Clinical Enzyme Tests; Drug Therapy, Combination; Folic Acid; Head and Neck Neoplasms; Humans; Methotrexate; Radioimmunoassay | 1979 |
In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
Topics: Aminopterin; Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tumor Cells, Cultured | 1992 |
A case-control study of nutrient status and invasive cervical cancer. I. Dietary indicators.
Topics: Ascorbic Acid; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Female; Folic Acid; Humans; Latin America; Neoplasm Invasiveness; Nutritional Status; Risk Factors; Uterine Cervical Neoplasms; Vitamin A | 1991 |
A case-control study of serum folate levels and invasive cervical cancer.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Case-Control Studies; Contraceptives, Oral; Female; Folic Acid; Humans; Middle Aged; Parity; Pregnancy; Risk Factors; South America; Uterine Cervical Neoplasms | 1991 |
Effect of intracellular folate concentration on the modulation of 5-fluorouracil cytotoxicity by the elevation of phosphoribosylpyrophosphate in cultured human KB cells.
Topics: Adenosine; Carcinoma, Squamous Cell; Cell Survival; Fluorouracil; Folic Acid; Glucose; Humans; KB Cells; Leucovorin; Leukemia, Myeloid, Acute; Methotrexate; Nasopharyngeal Neoplasms; Pentosephosphates; Phosphoribosyl Pyrophosphate; Thymidine | 1987 |
A comparison of dihydrofolate reductase activity in intact leukemia cells and squamous cell carcinoma.
Topics: Animals; Biological Transport; Carcinoma, Squamous Cell; Cell Count; DNA, Neoplasm; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Leukemia L1210; Methotrexate; Oxidation-Reduction; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured | 1989 |
Influence on immunoreactive folate-binding proteins of extracellular folate concentration in cultured human cells.
Topics: Animals; Breast Neoplasms; Carcinoma, Squamous Cell; Carrier Proteins; Cell Line; Cells, Cultured; Culture Media; Fibroblasts; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lymphocytes; Mammary Neoplasms, Experimental; Nasopharyngeal Neoplasms; Radioimmunoassay; Receptors, Cell Surface; Tumor Cells, Cultured | 1988 |
Accelerated split-course radiotherapy and simultaneous cis-dichlorodiammine-platinum and 5-fluorouracil chemotherapy with folinic acid enhancement for unresectable carcinoma of the head and neck.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Gamma Rays; Head and Neck Neoplasms; Humans; Male; Middle Aged; Radiotherapy Planning, Computer-Assisted | 1987 |
The influence of extracellular folate concentration on methotrexate uptake by human KB cells. Partial characterization of a membrane-associated methotrexate binding protein.
Topics: Animals; Carcinoma, Squamous Cell; Carrier Proteins; Cell Division; Chickens; Chromatography, Gel; Chromatography, High Pressure Liquid; Cross Reactions; Culture Media; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Methotrexate; Molecular Weight; Octoxynol; Polyethylene Glycols; Receptors, Cell Surface; Solubility; Subcellular Fractions; Tetrahydrofolate Dehydrogenase; Tissue Distribution | 1986 |
Studies of the role of a particulate folate-binding protein in the uptake of 5-methyltetrahydrofolate by cultured human KB cells.
Topics: Carcinoma, Squamous Cell; Carrier Proteins; Cell Line; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Molecular Weight; Receptors, Cell Surface; Temperature; Tetrahydrofolates; Time Factors; Trypsin | 1985 |
[Bronchial epidermoid cancer with normochromic megaloblastic anemia caused by folic acid deficiency].
Topics: Administration, Oral; Aged; Anemia, Macrocytic; Bronchial Neoplasms; Carcinoma, Squamous Cell; Folic Acid; Folic Acid Deficiency; Humans; Injections, Intramuscular; Male; Vitamin B 12 | 1969 |
Sequential chemotherapy and radiation therapy of buccal mucosa carcinoma in South India. Methods and preliminary results.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cheek; Cobalt Isotopes; Deoxyuridine; Female; Fluorouracil; Folic Acid; Humans; India; Leukocyte Count; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage | 1968 |