folic acid has been researched along with Cancer of Lung in 209 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (9.57) | 18.7374 |
| 1990's | 8 (3.83) | 18.2507 |
| 2000's | 44 (21.05) | 29.6817 |
| 2010's | 92 (44.02) | 24.3611 |
| 2020's | 45 (21.53) | 2.80 |
| Authors | Studies |
|---|---|
| Morioka, S; Motoyama, K; Onodera, R; Tahara, K; Takeuchi, H; Unida, S | 1 |
| Ji, J; Kong, X; Liu, D; Qiu, N; Xi, Y; Yang, X; Ye, L; Zhai, G; Zhang, J; Zhang, Y | 1 |
| Dai, J; Jiang, G; Jin, K; Li, Z; Xu, K; Xu, L; Yang, Y; Zhu, Y | 1 |
| Augustin, E; Bujak, P; Kasprzak, A; Kowalczyk, A; Kowalik, P; Nowicka, AM; Paluszkiewicz, E; Pilch, J | 1 |
| El-Kemary, M; Elashkar, AA; Essa, ML; Hanafy, NAN; Saied, EM | 1 |
| Arote, RB; Cheon, JH; Cho, KS; Cho, MH; Chun, HB; Kim, S; Lee, AY | 1 |
| Chen, D; Hu, Y; Low, PS; Napoleon, JV; Savran, CA; Singhal, S; Srinivasarao, M | 1 |
| Chen, J; Huang, L; Li, X; Lin, J; Tu, Y; Zheng, R | 1 |
| Azari, FS; Bernstein, E; Chang, A; Desphande, C; Din, A; Keating, J; Kennedy, GT; Kucharczuk, JC; Marfatia, I; Nadeem, B; Newton, A; Okusanya, O; Predina, J; Segil, A; Singhal, S | 1 |
| Azari, F; Chang, A; Delikatny, EJ; Desphande, C; Din, A; Kennedy, G; Kucharczuk, J; Marfatia, I; Nadeem, B; Singhal, S; Sullivan, N | 1 |
| Ahlawat, P; Bal, A; Phutela, K; Sharma, S; Singh, N | 1 |
| Baudouin, A; Beaurain, M; Couraud, S; Herledan, C; Ranchon, F; Rioufol, C; Souquet, PJ; Teixeira, A; Vantard, N | 1 |
| Annema, JT; Bonta, PI; Kramer, T | 1 |
| Behera, C; Kumari, P; Mahto, SK; Mehata, AK; Muthu, MS; Suseela, MNL | 1 |
| Hou, L; Hu, J; Jiang, G; Li, D; Li, S; Sun, L; Yan, Y; Yu, H; Zhang, L; Zhang, P | 1 |
| Chen, P; Duan, Y; Guo, H; He, Q; Liu, L; Mao, G; Qin, X; Shi, H; Song, Y; Tang, G; Wang, B; Wang, Z; Wei, Y; Xu, B; Yuan, H; Zhang, H; Zhang, Q; Zhang, X; Zhou, Z | 1 |
| Girase, ML; Ige, PP; Jain, PD; Nangare, SN; Sugandhi, VV | 1 |
| El-Brolsy, HMEM; El-Kemary, MA; Hanafy, NAN | 1 |
| Chen, JS; Chen, TE; Chen, YC; Cheng, ML; Huang, RS; Lin, YS; Lynn, KS; Shah, P | 1 |
| Aragaki, M; Bernards, N; Gregor, A; Hiraishi, Y; Ishiwata, T; Sata, Y; Yasufuku, K | 1 |
| Azari, F; Bou-Samra, P; Chang, A; Delikatny, E; Din, A; Doraid, J; Galandarova, A; Ibrahimli, A; Karimov, Z; Kennedy, G; Kucharczuk, J; Nadeem, B; Pechet, T; Singhal, S; Zhang, K | 1 |
| Li, Q; Lin, Y; Lin, Z; Xu, Y | 1 |
| Chen, WJ; Chen, YW; Huang, RS; Huang, SY; Liu, YF | 1 |
| Jia, ML; Liu, SY; Liu, W; Yang, H; Zeng, XF; Zhang, W; Zhu, WT | 1 |
| Buddolla, V; Kim, YJ; Lakshmi, BA; Varaganti, P | 1 |
| Chen, L; Du, B; Jiang, S; Ma, B; Wang, B; Wang, H; Xu, X; Yang, Y; Zhang, Z; Zhou, B; Zhu, J; Zhu, Y | 1 |
| Amirishoar, M; Ganji, S; Jafari, SM; Jahedi, R; Kharazmi, MS; Narmani, A | 1 |
| Hashimoto, M; Hirano, S; Katsuya, Y; Kobayashi, K; Naka, G; Suzuki, M; Takeda, Y; Uemura, Y | 1 |
| Chen, F; Hao, Y; Ni, Y; Qiang, G; Tian, Z; Zhang, J | 1 |
| Ahmed, RA; Amreddy, N; Munshi, A; Ramesh, R | 1 |
| Buque, A; Casares, N; Galluzzi, L | 1 |
| Chen, F; Liu, F; Lv, Q; Wen, T | 1 |
| Bhosle, J; Gunapala, R; Hodgkiss, A; Kumar, R; Mak, D; Minchom, A; O'Brien, MER; Popat, S; Walder, D; Yousaf, N | 1 |
| Ai, Y; Du, X; Song, Y; Wang, Y; Xia, Z; Zhang, J; Zhao, G; Zhou, B | 1 |
| Banerjee, S; Banerji, U; Cojocaru, E; Scaranti, M | 1 |
| Hennink, WE; Kok, RJ; Liu, Y; Lou, B; Shi, H; van Steenbergen, MJ | 1 |
| He, Z; Li, H; Liu, L; Liu, Y; Luo, M; Shao, B; Tie, Y; Wei, X; Wu, M; Yang, J; Yuan, X; Zhang, X; Zheng, H | 1 |
| Badanthadka, M; Chokshi, N; Khatri, H; Patel, BM; Patel, MM; Rawal, S | 1 |
| Bae, JM | 1 |
| Cui, H; Ma, Q; Shi, W; Xue, G; Zhang, J; Zhang, L | 1 |
| Aydin, C; Esendagli, G; Karpuz, M; Ozer, AY; Ozturk, SC; Silindir-Gunay, M; Tuncel, M; Yanik, H | 1 |
| Alfar, RA; Broman, MM; Cresswell, GM; Crist, SA; Dimitrov, DS; Elzey, BD; Eruslanov, EB; Kischuk, EM; Kularatne, SA; Low, PS; Ratliff, TL; Singhal, S; Sundaram, CP; Vickman, RE; Wang, B | 1 |
| Álvarez, MA; Álvarez-González, B; Fernández-Perales, M; Rozalen, M; Sánchez-Polo, M | 1 |
| Dank, M; Forika, G; Kiss, E; Krenacs, T; Mohacsi, R; Nemeth, Z | 1 |
| Luo, T; Qian, F; Que, Z; Tian, J; Yao, J; Yao, W; Yu, P; Zhang, Z; Zheng, D | 1 |
| Chang, YC; Chou, YT; Ho, CT; Hsiao, SH; Liu, JJ; Shen, PW | 1 |
| Christoph, DC; Flom, E; Kollmeier, J; Mairinger, FD; Mairinger, T; Popper, HH; Schmid, KW; Vollbrecht, C; Walter, RFH | 1 |
| Baszuk, P; Durda, K; Gupta, S; Jakubowska, A; Jaworska-Bieniek, K; Kaczmarek, K; Kąklewski, K; Lubiński, J; Narod, S; Sukiennicki, G; Szydłowski, M; Waloszczyk, P | 1 |
| Bharti, S; Koch, B; Muthu, MS; Pandey, BL; Sharma, G; Singh, RP; Singh, S | 1 |
| Aksoy-Sagirli, P; Erdenay, A; Kaytan-Saglam, E; Kizir, A | 1 |
| Kasinski, AL; Low, PS; Lyle, LT; Orellana, EA; Rangasamy, L; Tenneti, S | 1 |
| Akbari, H; Davaran, S; Eskandani, M; Johari-Ahar, M; Nemati, A; Omidi, Y; Ranjbar-Navazi, Z | 1 |
| Albanes, D; Arslan, AA; Blot, WJ; Bolton, JH; Brennan, P; Buring, JE; Butler, LM; Cai, Q; Caporaso, NE; Ericson, U; Fanidi, A; Freedman, ND; Gao, YT; Gaziano, JM; Giles, GG; Giovannucci, E; Grankvist, K; Haiman, CA; Han, J; Hodge, AM; Johansson, M; Koh, WP; Krokstad, S; Lan, Q; Langhammer, A; Le Marchand, L; Lee, IM; Li, H; Manjer, J; McCullough, ML; Midttun, Ø; Muller, DC; Næss, M; Pettinger, M; Prentice, R; Purdue, M; Relton, C; Sesso, HD; Severi, G; Shu, XO; Smith-Warner, SA; Stampfer, MJ; Stevens, VL; Thomsen, CA; Ueland, PM; Ulvik, A; Visvanathan, K; Wang, R; Weinstein, SJ; Wilkens, LR; Wu, J; Xiang, YB; Yuan, JM; Zeleniuch-Jacquotte, A; Zhang, X; Zheng, W; Ziegler, RG | 1 |
| Du, J; Li, C; Liu, Y; Wang, L; Wang, Y; Zhao, J; Zhou, Y | 1 |
| Buys, SS; Gren, LH; Hashibe, M; Kawakita, D; La Vecchia, C; Lee, YA | 1 |
| Chen, WJ; Huang, RS | 1 |
| Amighi, K; Gelbcke, M; Hecq, J; Mathieu, V; Mathivet, T; Rosière, R; Van Antwerpen, P; Van Woensel, M; Vermeersch, M; Wauthoz, N | 1 |
| Alam, IS; Gambhir, SS; Joosten, SCM; Rogalla, S; Vermesh, O | 1 |
| Angelopoulou, A; Avgoustakis, K; Liaskoni, A; Popescu, MT; Tsitsilianis, C; Voulgari, E | 1 |
| Tan, S; Wang, G | 1 |
| Mansfield, AS; Peikert, T; Symanowski, JT; Vogelzang, NJ | 1 |
| Chen, Q; Liu, J | 1 |
| Chan, L; Chen, T; Gao, P; He, L; Luo, L; Mei, C; Shi, C; Xiao, Z; Zhang, D | 1 |
| Chen, X; Gotoh, N; Horike, SI; Igarashi, K; Kato, K; Kita, K; Kohno, S; Meguro-Horike, M; Mukaida, N; Murayama, T; Nakata, A; Nishi, K; Nishimura, T; Saitoh, K; Sasaki, S; Soga, T; Takahashi, C; Tojo, A; Yano, S | 1 |
| Arya, M; Kaithwas, G; Kanoujia, J; Parashar, P; Saraf, SA; Singh, M; Tripathi, CB; Yadav, A | 1 |
| Chen, X; Kong, Y; Li, N; Liu, Q; Lu, X; Lu, Y; Xing, H; Xu, J; Yang, Y; Zhao, D; Zhu, X | 1 |
| Agrawal, AK; Aqil, F; Gupta, RC; Jeyabalan, J; Kyakulaga, AH; Munagala, R; Wilcher, SA | 1 |
| Blot, WJ; Buchowski, MS; Cai, Q; Hargreaves, MK; Munro, HM; Shu, XO; Steinwandel, MD; Takata, Y; Wen, W | 1 |
| Bezdetnaya, L; Lequeux, N; Mangeolle, T; Marchal, F; Pons, T; Yakavets, I | 1 |
| Borzyszkowska, J; Dziadziuszko, R; Janowicz, A; Jassem, J; Krzemiński, M; Limon, J; Rzyman, W; Stanisławska-Sachadyn, A | 1 |
| Ravi Shankaran, D; Shruthi, S; Thambiraj, S; Vijayalakshmi, R | 1 |
| Agudo, A; Allen, NE; Baltar, VT; Barricarte, A; Boeing, H; Boshuizen, H; Boutron-Ruault, MC; Brennan, P; Bueno-de-Mesquita, B; Castaño, JM; Chuang, SC; Clavel-Chapelon, F; Crowe, F; Fagherazzi, G; Ferrari, P; Gallo, V; Hallmans, G; Jenab, M; Johansson, M; Kaaks, R; Khaw, KT; Krogh, V; Lagiou, P; Larrañaga, N; Masala, G; Midttun, Ø; Navarro, C; Norat, T; Onland-Moret, NC; Panico, S; Rasmuson, T; Relton, C; Riboli, E; Rodríguez, L; Rohrmann, S; Roswall, N; Sacerdote, C; Slimani, N; Tjønneland, A; Trichopoulos, D; Trichopoulou, A; Tumino, R; Ueland, PM; van Gils, CH; Vineis, P; Wareham, N; Weikert, C; Xun, WW | 1 |
| Hee Oh, Y; Jeong, YS; Jo, SM; Kim, HS; Kim, Y; Park, K | 1 |
| Abdeen, S; Alexander, P; Bhagat, M; Chavali, M; Praseetha, PK; Rose, PA | 1 |
| Hu, C; Lei, B; Liu, Y; Nie, G; Qin, J; Rong, J; Xiao, Y; Zheng, M | 1 |
| Chen, L; Chu, XY; Dai, WM; Wang, YQ; Yang, B; Zhang, GQ; Zhao, M | 1 |
| Allen, TC | 1 |
| Azevedo, E; Kameo, SY; Martins-Filho, PR; Mascarenhas-Oliveira, AC; Vieira, NF | 1 |
| Chang, GC; Chiu, LY; Hsu, SL; Huang, YR; Sheu, GT; Yang, TY | 1 |
| Belinsky, SA; Bruse, SE; Flores, KG; Gauderman, WJ; Gilliland, FD; Leng, S; Liu, Y; Picchi, MA; Stidley, CA; Thomas, CL; Van Den Berg, D; Zhang, X | 1 |
| Caddick, S; Cal, PM; Chudasama, V; Cordeiro, C; Frade, RF; Gois, PM | 1 |
| Gao, HF; Hou, AJ; Zhang, HW; Zhang, YF; Zhou, L; Zhou, YH | 1 |
| Jing, X; Liu, S; Sun, Y; Tong, T; Wang, R; Wu, W; Zhang, F; Zhang, H; Zhang, Y | 1 |
| Helke, KL; Kistner-Griffin, E; Krupenko, NI; Krupenko, SA; Oleinik, NV | 1 |
| Aggarwal, AN; Behera, D; Kaur, J; Singh, N | 1 |
| Hosomi, Y; Iguchi, M; Nagamata, M; Nakahara, Y; Okamoto, H; Okamura, T; Okuma, Y; Shibuya, M; Shimokawa, T; Sunami, K; Takagi, Y; Yomota, M | 1 |
| Rai, V | 1 |
| Aggarwal, C; Albelda, S; Barbosa, EM; DeJesus, E; Deshpande, C; Jiang, J; Judy, R; Low, PS; Nie, S; Okusanya, OT; Simone, CB; Singhal, S | 1 |
| Horai, T; Horiike, A; Kudo, K; Nishio, M; Ohyanagi, F; Saito, R; Sakatani, T; Tanaka, H; Yanagitani, N | 1 |
| Chohnabayashi, N; Gotoh, K; Jinta, T; Kitamura, A; Koyama, K; Nishimura, N; Ohde, S; Okafuji, K; Takayama, S; Tomishima, Y; Tsuda, Y; Yagi, N | 1 |
| Duan, X; Kong, F; Wang, W; Wang, Y; Xi, M | 1 |
| Behera, D; Maturu, VN; Singh, N | 1 |
| Hosomi, Y; Okamoto, H; Shibuya, M; Takagi, Y | 1 |
| Berezowska, S; Dorn, P; Froment, L; Hall, SR; Kocher, G; Liang, SQ; Marti, TM; Peng, RW; Schmid, RA | 1 |
| Amighi, K; Gelbcke, M; Mathieu, V; Rosière, R; Van Antwerpen, P; Wauthoz, N | 1 |
| Albelda, SM; Deshpande, C; Drebin, JA; Heitjan, DF; Keating, JJ; Kennedy, GT; Litzky, LA; Low, PS; Nie, S; Okusanya, OT; Singhal, S | 1 |
| Bozbey, HU; Erturk, K; Kiziltan, H; Olmuscelik, O; Tas, F; Tastekin, D; Tuna, S | 1 |
| Gu, D; Hu, L; Hu, Q; Kong, D; Pang, S; Su, J; Xiong, X | 1 |
| He, Z; Huang, C; Huang, J; Sun, W; Teng, Y; Wu, Y; Xu, Y; Zhang, H; Zhang, X | 1 |
| Aqil, F; Gupta, RC; Jeyabalan, J; Munagala, R | 1 |
| Hu, Y; Shi, X; Wang, Z; Xu, Y; Yang, J; Zhang, C; Zhang, G; Zhang, Z | 1 |
| Chen, W; He, Z; Huang, J; Ma, J; Shi, Z; Sun, W; Xia, J; Zhang, X | 1 |
| Luther, E; Pan, J; Sarisozen, C; Sriraman, SK; Torchilin, V | 1 |
| Hosomi, Y; Nagamata, M; Nakahara, Y; Okamura, T; Okuma, Y; Shimokawa, T; Sunami, K; Takagi, Y; Takahashi, S; Watanabe, K; Yomota, M | 1 |
| Amighi, K; Langer, I; Mathieu, V; Mathivet, T; Rosière, R; Van Woensel, M; Vermeersch, M; Wauthoz, N | 1 |
| Chang, CW; Kuan, CH; Lin, CJ; Wang, LW; Wang, TW; Wu, HC; Wu, YF | 1 |
| Liu, S; Ouyang, M; Peng, Y; Qin, Y; Yang, H; Zeng, X; Zhou, C | 1 |
| Christoph, DC; Hager, T; Mairinger, FD; Schmid, KW; Vollbrecht, C; Walter, RF; Werner, R; Wohlschlaeger, J | 1 |
| Amreddy, N; Babu, A; Basalingappa, K; Chen, A; Kompella, UB; Mehta, M; Munshi, A; Muralidharan, R; Ramesh, R; Zhao, YD | 1 |
| Cho, MH; Cui, PF; Jang, Y; Jiang, HL; Kim, HJ; Lee, AY; Luo, CQ; Qiao, JB; Xing, L | 1 |
| Ekgasit, S; Komenek, S; Luesakul, U; Muangsin, N; Praphairaksit, N; Puthong, S; Vilaivan, T | 1 |
| Aggarwal, C; Alley, EW; Bagley, SJ; Blair, IA; Cohen, RB; Evans, TL; Langer, CJ; Vachani, A; Vitale, S; Whitehead, AS; Zhang, S | 1 |
| Cao, Y; Ma, Q; Wang, F; Wang, Y; Yu, B | 1 |
| Hu, LL; Li, ZP; Liu, J; Wang, AW; Wang, ZD; Zhao, QS | 1 |
| Baldi, M; Behera, D; Kapoor, R; Kaur, J; Singh, N | 1 |
| Banerjee, T; Heckert, B; Kallu, J; Naz, S; Santra, S; Shelby, T; Sulthana, S; Vuppala, SR; Yambem, O | 1 |
| Adachi, S; Fujimoto, T; Fukuoka, M; Ichinose, Y; Kubota, K; Nakagawa, K; Nambu, Y; Nishiwaki, Y; Ohe, Y; Saijo, N; Tamura, T; Yamamoto, N | 1 |
| Bearz, A; Pampaloni, G; Russo, F | 1 |
| Bromund, JL; Chen, R; Neubauer, M; Obasaju, C; Raju, RN; Reynolds, CH; Richards, DA; Ruxer, RL; Savin, M; Smith, DA; Socinski, MA; Zhan, F | 1 |
| Albanes, D | 1 |
| Lu, W; Luo, QY; Pang, DW; Shi, YB; Song, EQ; Zhang, ZL | 1 |
| Guo, Y; Holley, AC; Huang, F; McCormick, CL; York, AW; Zhang, Y | 1 |
| Arpin, D; Biron, E; Cadranel, J; Duruisseaux, M; Guérin, JC; Pérol, M | 1 |
| Cerny, T; D'Addario, G; Früh, M; Gillessen, S; Omlin, A; von Hessling, A | 1 |
| Brown, K; Gescher, AJ; Scott, EN; Steward, WP | 1 |
| Arote, R; Cho, CS; Cho, MH; Jere, D; Jiang, HL; Kim, YK; Lim, HT; Xu, CX | 1 |
| Fukui, Y; Jin, M; Kawakami, K; Minamoto, T; Oda, M; Oka, T; Takechi, T; Tsukioka, S; Watanabe, G | 1 |
| Bosch-Barrera, J; Ceballos, J; Ferrer, M; García-Foncillas, J; Gaztañaga, M; Gil-Bazo, I; Idoate, MA; López-Picazo, JM; Pérez-Gracia, JL; Pretel, M; Sanz, ML | 1 |
| Christensen, J; Dragsted, LO; Olsen, A; Overvad, K; Roswall, N; Tjønneland, A | 1 |
| Hernán, MA; Hernández-Díaz, S; VanderWeele, TJ | 1 |
| Roswall, N | 1 |
| Barata, F; Barlesi, F; Bearz, A; Bepler, G; Chiappori, A; Chouaki, N; Iscoe, N; Liepa, AM; Park, K; Reck, M; Scagliotti, G; Soria, JC; von Pawel, J; Wagle, A; Zhao, YD | 1 |
| Arote, RB; Cho, CS; Jere, D; Jiang, HL; Kim, TH; Kim, YK; Park, IK; Yoon, MK | 1 |
| Colditz, GA; Wei, EK; Wolin, KY | 1 |
| Barz, M; Canal, F; Koynov, K; Vicent, MJ; Zentel, R | 1 |
| Cortes, A; El-Zein, RA; Etzel, CJ; Greisinger, AJ; Lopez, MS; Monroy, C; Piskac-Collier, AL; Spitz, MR | 1 |
| Azzoli, CG; Dunne, M; Ginsberg, M; Huntington, M; James, L; Kris, MG; Krug, LM; May, J; Miller, V; Patel, JD; Saunders, M; Sirotnak, FM; Subzwari, S; Tyson, L | 1 |
| Asomaning, K; Christiani, DC; Lee, MS; Mark, EJ; Su, L; Wain, JC | 1 |
| Edelman, MJ; Pribble, P | 1 |
| Cho, CS; Cho, MH; Choi, YJ; Jiang, HL; Kim, YK; Lee, SJ; Lim, HT; Park, IK; Yoo, MK | 1 |
| Blassnigg, SM; Bulmer, AC; Doberer, D; Knasmüller, S; Marculescu, R; Marisch, K; Mölzer, C; Müllner, E; Nersesyan, A; Pappenheim, MT; Wagner, KH; Wallner, M | 1 |
| Desmoulin, SK; Gangjee, A; Hou, Z; Matherly, LH | 1 |
| Boccia, RV; Bonomi, P; Conley, BA; Edelman, MJ; Garon, EB; Harb, WA; Kraut, MJ; Messmann, RA; Pal, SE; Rogers, JS | 1 |
| Cagle, PT; Low, PS; Murphy, L; Zhai, QJ | 1 |
| Peng, C; Shen, M; Shi, X; Wang, H; Zhang, G; Zheng, L | 1 |
| Igawa, S; Katono, K; Maki, S; Masuda, N; Otani, S; Ryuge, S; Sasaki, J; Sato, Y; Takakura, A; Wada, M | 1 |
| Hassan, R; Maltzman, J; Thomas, A | 1 |
| Cai, H; Gao, J; Gao, YT; Li, H; Shu, XO; Takata, Y; Xiang, YB; Yang, G; Zheng, W | 1 |
| Forman, MR; Hernandez, LM; Lupo, PJ; Peterson, CB; Shete, S; Spitz, MR; Swartz, MD; Vannucci, M; Wu, X | 1 |
| Hirata, T; Honda, H; Kato, H; Saito, M; Tsuchida, T | 1 |
| Ando, M; Ito, Y; Kondo, T; Nishino, Y; Ohno, Y; Ozasa, K; Seki, N; Suzuki, K; Tamakoshi, A; Wakai, K; Watanabe, Y | 2 |
| KARLIN, R | 1 |
| COSTAKEL, O | 1 |
| Amos, CI; Hong, WK; Pillow, PC; Shen, H; Spitz, MR; Wei, Q | 1 |
| Adjei, AA | 1 |
| Fossella, FV; Herbst, RS; Zinner, RG | 1 |
| Chen, IW; Choi, H; Choi, SR; Kung, HF; Zhou, R | 1 |
| Andel, M; Hyánek, J; Janosíková, B; Kozich, V; Pavlíková, M; Veselá, K; Zvárová, J | 1 |
| Budde, LS; Hanna, NH | 1 |
| Berndt, SI; Caporaso, N; Chanock, S; He, X; Lan, Q; Rothman, N; Shen, M; Welch, R; Yeager, M | 1 |
| Scagliotti, GV | 1 |
| Bavetsias, V; Forster, MD; Gibbs, DD; Green, M; Henderson, E; Jackman, AL; Mitchell, F; Raynaud, F; Theti, DS; Valenti, M; Wood, N | 1 |
| Bushell, TM; Johanning, GL; Piyathilake, CJ; Whiteside, MA | 1 |
| Hida, T; Hiraki, A; Matsuo, K; Mitsudomi, T; Saito, T; Sato, S; Suzuki, T; Tajima, K; Ueda, R; Yatabe, Y | 1 |
| Bridle, H; Eisen, T; El Galta, R; Houlston, RS; Matakidou, A; Rudd, MF; Webb, EL | 1 |
| Leamon, CP; Nicoson, JS; Parker, N; Reddy, JA; Vetzel, M; Vlahov, IR; Westrick, E | 1 |
| Jiang, QJ; Liu, SY; Xiao, XS; Yuan, Z; Zhong, GR | 1 |
| Chattopadhyay, S; Goldman, ID; Min, SH; Tamari, R; Tsai, E; Zhao, R | 1 |
| Clarke, SJ; Li, KM; Rivory, LP | 1 |
| Au, DH; Littman, AJ; Satia, JA; Slatore, CG; White, E | 1 |
| Clamon, GH; DeWys, WD; Evans, WK; Feld, R; Gardner, LB; Hoffman, FA; Kramer, BS; Lininger, LL; Weiner, RS; Wolfe, EC | 1 |
| Chabner, BA; Clendeninn, NJ; Cowan, KH; Curt, GA; Jolivet, J | 1 |
| da Costa, M; Fisher, C | 1 |
| Bhide, SV; Maru, GB | 1 |
| Bhide, SV; Maru, GB; Sawai, MM | 1 |
| Bunn, PA; Christensen, K; Edwards, D; Franklin, WA; Kolhouse, JF; Prendegrast, P; Waintrub, M; Woods, J | 1 |
| Iigo, M; Moriyama, M; Suzuki, I; Tsuda, H | 1 |
| Gürdal-Yüksel, E; Karadağ, M; Kunt-Uzaslan, AE; Ozyardimci, N; Yarkin, T | 1 |
| Daly, BD; Jatoi, A; Kramer, G; Mason, JB | 2 |
| Faessel, HM; Greco, WR; Rustum, YM; Slocum, HK | 1 |
| Kim, YI | 1 |
| Brants, HA; Goldbohm, RA; Hermus, RJ; Sturmans, F; van den Brandt, PA; van Poppel, GA; Voorrips, LE | 1 |
| Backus, HH; Jansen, G; Molders, N; Padrón, JM; Peters, GJ; Pinedo, HM; van Der Wilt, CL; van Groeningen, CJ; Wouters, D | 1 |
| Grizzle, WE; Heimburger, DC; Johanning, GL; Macaluso, M; Oelschlager, DK; Piyathilake, CJ; Whiteside, M | 1 |
| Heber, D | 1 |
| Borisov, VV; Karelin, AA; Korotkina, RN; Kunitsyn, AG; Matskevich, GN; Polikarpova, LV; Vishnevskii, AA | 1 |
| Albanes, D; Barrett, MJ; Hartman, TJ; Selhub, J; Stolzenberg-Solomon, R; Virtamo, J; Woodson, K | 1 |
| Hong, WK; Shen, H; Spitz, MR; Wang, LE; Wei, Q | 1 |
| Krupenko, SA; Oleinik, NV | 1 |
| Fairfield, KM; Fletcher, RH | 1 |
| Bunn, PA | 1 |
| Archer, MC; Paglialunga, S; Tannenbaum, SR; Wogan, GN | 1 |
| Janka, G | 1 |
| Bratseva, VL | 1 |
| Straus, MJ | 1 |
| Aherne, GW; Curtin, NJ; Harris, AL | 1 |
| Friedman, GD; Selby, JV | 1 |
| Goodman, MT; Hankin, JH; Kolonel, LN; Le Marchand, L; Yoshizawa, CN | 1 |
| Fireman, BH; Friedman, GD; Selby, JV | 1 |
| Aherne, GW; Curtin, NJ; Harris, AL; Marks, V; Piall, EM | 1 |
| Curtin, NJ; Harris, AL | 1 |
| Ambaye, RY; Ganu, UK; Gokhale, SV | 1 |
| Bukhman, VM; Novikova, LA; Pavlotskii, AI; Svet-Moldavskii, GIa; Toloknov, BO | 1 |
| McGREGOR McGregor, RF; Nelson, RS; Somayaji, BN | 1 |
| Karlin, R; Viallier, J | 1 |
| Ishihara, S | 1 |
21 review(s) available for folic acid and Cancer of Lung
| Article | Year |
|---|---|
Recent advances in using folate receptor 1 (FOLR1) for cancer diagnosis and treatment, with an emphasis on cancers that affect women.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms; Ovarian Neoplasms | 2023 |
The value of folate receptor-positive circulating tumour cells as a diagnostic biomarker for lung cancer: a systematic review and meta-analysis.
Topics: Area Under Curve; Biomarkers, Tumor; Folic Acid; Humans; Lung Neoplasms; Neoplastic Cells, Circulating | 2023 |
Associations between Folate Metabolism Enzyme Polymorphisms and Lung Cancer: A Meta-Analysis.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alleles; Asian People; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Association Studies; Homocystinuria; Humans; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Psychotic Disorders; Risk Factors; Smoking | 2020 |
Exploiting the folate receptor α in oncology.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Endometrial Neoplasms; Female; Fluorescent Dyes; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; Humans; Immunoconjugates; Immunologic Factors; Immunotherapy, Adoptive; Lung Neoplasms; Maytansine; Mesothelioma; Molecular Imaging; Molecular Targeted Therapy; Neoplasms; Optical Imaging; Ovarian Neoplasms; Radionuclide Imaging; Theranostic Nanomedicine; Tubulin Modulators | 2020 |
Serum Folate Levels and Lung Cancer Risk: A Meta- Epidemiological Study of Population-based Case-Control Studies.
Topics: Biomarkers, Tumor; Case-Control Studies; Epidemiologic Studies; Folic Acid; Humans; Lung Neoplasms; Prognosis; Risk Factors | 2020 |
Association between folate intake, serum folate levels and the risk of lung cancer: a systematic review and meta-analysis.
Topics: Folic Acid; Humans; Lung Neoplasms; Risk Factors | 2013 |
Association between folate intake and the risk of lung cancer: a dose-response meta-analysis of prospective studies.
Topics: Anticarcinogenic Agents; Cohort Studies; Female; Folic Acid; Humans; Incidence; Lung; Lung Neoplasms; Male; Prospective Studies; Risk Factors; Sex Factors; Vitamin B Complex | 2014 |
Folate pathway gene MTHFR C677T polymorphism and risk of lung cancer in Asian populations.
Topics: Asian People; Case-Control Studies; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Lung Neoplasms; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Risk Factors; Signal Transduction | 2014 |
Development of dietary phytochemical chemopreventive agents: biomarkers and choice of dose for early clinical trials.
Topics: Animals; Anticarcinogenic Agents; beta Carotene; Biomarkers; Cell Line, Tumor; Clinical Trials as Topic; Colorectal Neoplasms; Diet; DNA Adducts; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; Folic Acid; Genistein; Humans; Lung Neoplasms; Male; Plant Extracts; Plants, Edible; Rats | 2009 |
Time course of risk factors in cancer etiology and progression.
Topics: Alcohol Drinking; Breast Neoplasms; Colorectal Neoplasms; Diet; Disease Progression; Female; Folic Acid; Humans; Lung Neoplasms; Male; Neoplasms; Prognosis; Prostatic Neoplasms; Risk Factors; Smoking | 2010 |
EC145: a novel targeted agent for adenocarcinoma of the lung.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lung Neoplasms; Vinca Alkaloids | 2012 |
The human proton-coupled folate transporter: Biology and therapeutic applications to cancer.
Topics: Biological Transport; Carcinoma, Non-Small-Cell Lung; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Lung Neoplasms; Mesothelioma; Molecular Targeted Therapy; Neoplasms; Pemetrexed; Proton-Coupled Folate Transporter | 2012 |
Farletuzumab in lung cancer.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms | 2013 |
[Chemoprevention of lung cancer].
Topics: beta Carotene; Bronchi; Drug Administration Schedule; Drug Therapy, Combination; Folic Acid; Humans; Lung Neoplasms; Metaplasia; Smoking Cessation; Vitamin B 12 | 2003 |
Pemetrexed (ALIMTA), a novel multitargeted antineoplastic agent.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Neoplasms; Pemetrexed; Platinum Compounds; Thymidylate Synthase; Vitamin B 12 | 2004 |
Pemetrexed in advanced NSCLC: a review of the clinical data.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dietary Supplements; Folic Acid; Glutamates; Guanine; Hematinics; Humans; Lung Neoplasms; Mesothelioma; Pemetrexed; Thymidylate Synthase; Vitamin B 12 | 2004 |
Antimetabolites in the management of non-small cell lung cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Pemetrexed; Survival; Treatment Outcome | 2005 |
The pharmacology and clinical use of methotrexate.
Topics: Administration, Oral; Animals; Biological Transport; Central Nervous System; Drug Resistance; Folic Acid; Folic Acid Antagonists; Gene Amplification; Head and Neck Neoplasms; Humans; Kinetics; Leucovorin; Leukemia, Lymphoid; Lung Neoplasms; Methotrexate; Neoplasms; Osteoma, Osteoid; Thymidylate Synthase; Tissue Distribution | 1983 |
Folate and cancer prevention: a new medical application of folate beyond hyperhomocysteinemia and neural tube defects.
Topics: Adolescent; Adult; Alcohol Drinking; Animals; beta Carotene; Breast Neoplasms; Case-Control Studies; Female; Folic Acid; Follow-Up Studies; Hematinics; Humans; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Middle Aged; Neoplasms; Odds Ratio; Pancreatic Neoplasms; Postmenopause; Premenopause; Prospective Studies; Randomized Controlled Trials as Topic; Rats; Risk; Risk Factors; Smoking; Time Factors; Vitamins | 1999 |
Vitamins for chronic disease prevention in adults: scientific review.
Topics: Ascorbic Acid; Avitaminosis; Blood Coagulation; Breast Neoplasms; Carotenoids; Chronic Disease; Colorectal Neoplasms; Coronary Disease; Dietary Supplements; Female; Folic Acid; Fractures, Bone; Humans; Lung Neoplasms; Male; Neoplasms; Neural Tube Defects; Prostatic Neoplasms; Risk Factors; Vitamin A; Vitamin B 12; Vitamin B 6; Vitamin D; Vitamin E; Vitamin K; Vitamins | 2002 |
Incorporation of pemetrexed (Alimta) into the treatment of non-small cell lung cancer (thoracic tumors).
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials as Topic; Deoxycytidine; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Folic Acid; Gemcitabine; Glutamates; Guanine; Humans; Lung Neoplasms; Mesothelioma; Pemetrexed; Pleural Neoplasms; Thymidylate Synthase; Vitamin B 12 | 2002 |
15 trial(s) available for folic acid and Cancer of Lung
| Article | Year |
|---|---|
Effects of Reduction in Tumor Burden on Survival in Epithelioid Malignant Pleural Mesothelioma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Folic Acid; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Middle Aged; Pemetrexed; Progression-Free Survival; Proportional Hazards Models; Tumor Burden; United States; Vitamin B 12; Vitamin B Complex | 2018 |
A prospective study of shortened vitamin supplementation prior to cisplatin-pemetrexed therapy for non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Pemetrexed; Prospective Studies; Treatment Outcome; Vitamin B 12 | 2014 |
The Optical Biopsy: A Novel Technique for Rapid Intraoperative Diagnosis of Primary Pulmonary Adenocarcinomas.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Biopsy; Female; Fluorescein-5-isothiocyanate; Folic Acid; Frozen Sections; Humans; Intraoperative Period; Lung; Lung Neoplasms; Male; Middle Aged; Optical Imaging; Pilot Projects; Predictive Value of Tests; Prospective Studies; Tomography, X-Ray Computed | 2015 |
Phase II study of oral vitamin B12 supplementation as an alternative to intramuscular injection for patients with non-small cell lung cancer undergoing pemetrexed therapy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Folic Acid; Homocysteine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 2016 |
[Clinical efficacy of vitamin support in lung adenocarcinoma patients treated with pemetrexed second-line chemotherapy].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Disease-Free Survival; Folic Acid; Humans; Lung Neoplasms; Pemetrexed; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2015 |
Pretreatment Red Blood Cell Total Folate Concentration Is Associated With Response to Pemetrexed in Stage IV Nonsquamous Non-Small-cell Lung Cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pemetrexed; Prognosis; Prospective Studies; Survival Rate; Vitamin B Complex | 2017 |
Rationale and Design of PEMVITASTART-An Open-label Randomized Trial Comparing Simultaneous Versus Standard Initiation of Vitamin B
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Dietary Supplements; Female; Folic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Patient Selection; Pemetrexed; Prospective Studies; Research Design; Treatment Outcome; Vitamin B 12; Young Adult | 2017 |
Efficacy and safety of two doses of pemetrexed supplemented with folic acid and vitamin B12 in previously treated patients with non-small cell lung cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Female; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Regression Analysis; Safety; Treatment Outcome; Vitamin B 12 | 2008 |
Pemetrexed in relapsed small-cell lung cancer and the impact of shortened vitamin supplementation lead-in time: results of a phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cohort Studies; Dietary Supplements; Female; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pemetrexed; Prognosis; Salvage Therapy; Small Cell Lung Carcinoma; Survival Rate; Thymidylate Synthase; Vitamin B Complex | 2008 |
Phase II, double-blinded, randomized study of enzastaurin plus pemetrexed as second-line therapy in patients with advanced non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Double-Blind Method; Female; Folic Acid; Glutamates; Guanine; Humans; Indoles; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Pemetrexed; Prognosis; Salvage Therapy; Survival Rate; Vitamin B 12 | 2010 |
Pralatrexate with vitamin supplementation in patients with previously treated, advanced non-small cell lung cancer: safety and efficacy in a phase 1 trial.
Topics: Adenocarcinoma; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Tissue Distribution; Vitamin B 12; Vitamin B Complex | 2011 |
Genetic determinants of folate status in Central Bohemia.
Topics: Aryl Hydrocarbon Hydroxylases; Czech Republic; Dietary Supplements; DNA Mutational Analysis; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Testing; Humans; Lung Neoplasms; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Middle Aged; Polymorphism, Genetic; Risk Assessment; Risk Factors | 2005 |
Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Deoxyuridine; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Glutamates; Guanine; Homocysteine; Humans; Lung Neoplasms; Male; Methylmalonic Acid; Middle Aged; Pemetrexed; Thymidine; Thymidylate Synthase; Vinblastine; Vinorelbine; Vitamin B 12 | 2007 |
Serum folate and vitamin B12 levels in patients with small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma, Small Cell; Energy Intake; Folic Acid; Humans; Lung Neoplasms; Parenteral Nutrition, Total; Random Allocation; Vitamin B 12 | 1984 |
Association of the B-vitamins pyridoxal 5'-phosphate (B(6)), B(12), and folate with lung cancer risk in older men.
Topics: Age Distribution; Aged; Case-Control Studies; Cohort Studies; Confidence Intervals; Finland; Folic Acid; Homocysteine; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Pyridoxine; Reference Values; Risk Factors; Sampling Studies; Sensitivity and Specificity; Vitamin B 12 | 2001 |
173 other study(ies) available for folic acid and Cancer of Lung
| Article | Year |
|---|---|
Design and evaluation of folate-modified liposomes for pulmonary administration in lung cancer therapy.
Topics: Animals; Antineoplastic Agents; Folic Acid; Liposomes; Lung; Lung Neoplasms; Mice | 2022 |
A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases.
Topics: Animals; Biocompatible Materials; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Doxorubicin; Female; Folic Acid; Humans; Hyperthermia, Induced; Infrared Rays; Lung Neoplasms; Mice; Mice, Inbred BALB C; Molybdenum; Nanostructures; Oxides; Polyethylene Glycols; Serum Albumin, Bovine; Thioctic Acid; Tissue Distribution | 2021 |
Predictive Value of Folate Receptor-Positive Circulating Tumor Cells for the Preoperative Diagnosis of Lymph Node Metastasis in Patients with Lung Adenocarcinoma.
Topics: Adenocarcinoma of Lung; Folic Acid; Humans; Lung Neoplasms; Lymphatic Metastasis; Neoplastic Cells, Circulating | 2021 |
Foliate-Targeting Quantum Dots-
Topics: Acridines; Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Lung; Lung Neoplasms; Male; Nanoconjugates; Nanostructures; Prostate; Prostatic Neoplasms; Quantum Dots | 2022 |
Dual targeting nanoparticles based on hyaluronic and folic acids as a promising delivery system of the encapsulated 4-Methylumbelliferone (4-MU) against invasiveness of lung cancer in vivo and in vitro.
Topics: Antineoplastic Agents; Cell Line, Tumor; Folic Acid; Humans; Hyaluronic Acid; Hymecromone; Lung Neoplasms; Nanocapsules; Nanoparticles; Polyethylene Glycols | 2022 |
Efficient gene transfection to lung cancer cells via Folate-PEI-Sorbitol gene transporter.
Topics: Cell Line, Tumor; Folic Acid; Humans; Lung Neoplasms; Polyethyleneimine; RNA, Small Interfering; Sorbitol; Transfection | 2022 |
Efficient capture of circulating tumor cells with low molecular weight folate receptor-specific ligands.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Count; Cell Line, Tumor; Cell Separation; Folic Acid; Humans; Ligands; Lung Neoplasms; Mice; Molecular Weight; Neoplastic Cells, Circulating | 2022 |
Folic acid-mediated MSNs@Ag@Geb multifunctional nanocomposite heterogeneous platform for combined therapy of non-small cell lung cancer.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Doxorubicin; Folic Acid; Gefitinib; Humans; Lung Neoplasms; Manganese Compounds; Metal Nanoparticles; Nanocomposites; Nanoparticles; Oxides; Silicon Dioxide; Silver | 2022 |
Comparative Experience of Short-wavelength Versus Long-wavelength Fluorophores for Intraoperative Molecular Imaging of Lung Cancer.
Topics: Fluoresceins; Fluorescent Dyes; Folic Acid; Humans; Intraoperative Care; Lung Neoplasms; Molecular Imaging | 2022 |
Presence of non-Newtonian fluid in invasive pulmonary mucinous adenocarcinomas impacts fluorescence during intraoperative molecular imaging of lung cancer.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adenocarcinoma, Mucinous; Contrast Media; Female; Fluorescent Dyes; Folic Acid; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Molecular Imaging; Mucins; Retrospective Studies; Sepharose; Tumor Microenvironment | 2022 |
Therapeutic potential of human serum albumin nanoparticles encapsulated actinonin in murine model of lung adenocarcinoma.
Topics: Adenocarcinoma of Lung; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Folic Acid; Humans; Hydroxamic Acids; Lung Neoplasms; Mice; Nanoparticles; Serum Albumin, Human | 2022 |
Intravenous route for folate supplementation in a patient with celiac disease treated by pemetrexed-based chemotherapy for non-small-cell lung cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Celiac Disease; Dietary Supplements; Folic Acid; Humans; Injections, Intravenous; Levoleucovorin; Lung Neoplasms; Pemetrexed | 2023 |
Shining new light on lung cancer diagnosis using a pafolacianine molecular tracer.
Topics: Folic Acid; Humans; Lung Neoplasms; Thorax | 2022 |
Chitosan-alginate nanoparticles of cabazitaxel: Design, dual-receptor targeting and efficacy in lung cancer model.
Topics: Alginates; Animals; Cell Line, Tumor; Chitosan; Folic Acid; Lung Neoplasms; Mice; Nanoparticles; Rats; Rats, Wistar | 2022 |
Comparative profiling of single-cell transcriptome reveals heterogeneity of tumor microenvironment between solid and acinar lung adenocarcinoma.
Topics: Adenocarcinoma of Lung; Biomarkers, Tumor; Carbon; Carcinoma, Acinar Cell; Folic Acid; Gene Expression Profiling; Humans; Lung Neoplasms; Prognosis; Proteomics; Transcriptome; Tumor Microenvironment | 2022 |
Serum total folate, 5-methyltetrahydrofolate and vitamin B12 concentrations on incident risk of lung cancer.
Topics: Adult; Case-Control Studies; Folic Acid; Humans; Lung Neoplasms; Prospective Studies; Risk Factors; Vitamin B 12; Vitamins | 2023 |
Design of surface tailored carboxymethyl dextran-protein based nanoconjugates for paclitaxel: Spectroscopical characterizations and cytotoxicity assay.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dextrans; Drug Carriers; Folic Acid; Humans; Lung Neoplasms; Membrane Proteins; Nanoconjugates; Nanoparticles; Paclitaxel; Polymers; Serum Albumin, Bovine | 2022 |
Fighting Non-Small Lung Cancer Cells Using Optimal Functionalization of Targeted Carbon Quantum Dots Derived from Natural Sources Might Provide Potential Therapeutic and Cancer Bio Image Strategies.
Topics: Carbon; Carcinoma, Non-Small-Cell Lung; Folic Acid; Humans; Lung Neoplasms; Microscopy, Fluorescence; Quantum Dots | 2022 |
Probing Folate-Responsive and Stage-Sensitive Metabolomics and Transcriptional Co-Expression Network Markers to Predict Prognosis of Non-Small Cell Lung Cancer Patients.
Topics: Amino Acid Transport System ASC; Carcinoma, Non-Small-Cell Lung; Folic Acid; Glutamine; Humans; Lung Neoplasms; Metabolomics; Minor Histocompatibility Antigens; Prognosis; Tandem Mass Spectrometry | 2022 |
Transbronchial real-time lung tumor localization with folate receptor-targeted near-infrared molecular imaging: A proof of concept study in animal models.
Topics: Animals; Disease Models, Animal; Folic Acid; Humans; Lung Neoplasms; Mice; Molecular Imaging; Optical Imaging; Proof of Concept Study | 2023 |
Prospective validation of tumor folate receptor expression density with the association of pafolacianine fluorescence during intraoperative molecular imaging-guided lung cancer resections.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Folic Acid; Humans; Lung Neoplasms; Molecular Imaging; Prospective Studies | 2023 |
The value of folate receptor-positive circulating tumor cells in the diagnosis of lung cancer and its correlation with clinical characteristics.
Topics: Biomarkers, Tumor; Folic Acid; Humans; Lung Neoplasms; Multiple Pulmonary Nodules; Neoplasm Staging; Neoplastic Cells, Circulating | 2023 |
Dietary Folate Deficiency Promotes Lactate Metabolic Disorders to Sensitize Lung Cancer Metastasis through MTOR-Signaling-Mediated Druggable Oncotargets.
Topics: Animals; Diet; Folic Acid; Folic Acid Deficiency; L-Lactate Dehydrogenase; Lactic Acid; Lung Neoplasms; Malnutrition; Mechanistic Target of Rapamycin Complex 1; Metabolic Diseases; Mice; Monocarboxylic Acid Transporters; TOR Serine-Threonine Kinases | 2023 |
Resveratrol Loaded by Folate-Modified Liposomes Inhibits Osteosarcoma Growth and Lung Metastasis via Regulating JAK2/STAT3 Pathway.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Folic Acid; Humans; Janus Kinase 2; Lipopolysaccharides; Liposomes; Lung Neoplasms; Mice; Osteosarcoma; Resveratrol; STAT3 Transcription Factor | 2023 |
Identify the Clinicopathological Characteristics of Lung Carcinoma Patients Being False Negative in Folate Receptor Based Circulating Tumor Cell Detection.
Topics: Adenocarcinoma of Lung; ErbB Receptors; Folic Acid; Humans; Lung; Lung Neoplasms; Lymphatic Metastasis; Neoplastic Cells, Circulating | 2023 |
Smart chitosan-PLGA nanocarriers functionalized with surface folic acid ligands against lung cancer cells.
Topics: Chitosan; Drug Carriers; Folic Acid; Glycols; Humans; Ligands; Lung Neoplasms; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer | 2023 |
Correlation of toxicities and efficacies of pemetrexed with clinical factors and single-nucleotide polymorphisms: a prospective observational study.
Topics: Carcinoma, Non-Small-Cell Lung; Folic Acid; Humans; Lung Neoplasms; Mesothelioma, Malignant; Pemetrexed; Polymorphism, Single Nucleotide | 2023 |
Tumor-Targeted Dendrimer Nanoparticles for Combinatorial Delivery of siRNA and Chemotherapy for Cancer Treatment.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Combined Modality Therapy; Dendrimers; Drug Delivery Systems; ELAV-Like Protein 1; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lung Neoplasms; Microscopy, Electron, Transmission; Nanoparticles; RNA, Small Interfering; Workflow | 2020 |
Today's Special on the Anticancer Menu: Immunomodulation by Antifolates.
Topics: Folic Acid; Folic Acid Antagonists; Humans; Immunomodulation; Immunotherapy; Lung Neoplasms; Mesothelioma; Pemetrexed | 2019 |
A prospective observational study of on-treatment plasma homocysteine levels as a biomarker of toxicity, depression and vitamin supplementation lead-in time pre pemetrexed, in patients with non-small cell lung cancer and malignant mesothelioma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carcinoma, Non-Small-Cell Lung; Depression; Dietary Supplements; Female; Folic Acid; Homocysteine; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Middle Aged; Pemetrexed; Prospective Studies; Treatment Outcome; Vitamin B 12; Vitamins | 2019 |
Folic acid (FA)-conjugated mesoporous silica nanoparticles combined with MRP-1 siRNA improves the suppressive effects of myricetin on non-small cell lung cancer (NSCLC).
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Drug Liberation; Drug Synergism; Female; Flavonoids; Folic Acid; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Multidrug Resistance-Associated Proteins; Nanoparticles; Poly (ADP-Ribose) Polymerase-1; Rats; RNA, Small Interfering | 2020 |
Folate decorated polymeric micelles for targeted delivery of the kinase inhibitor dactolisib to cancer cells.
Topics: A549 Cells; Acrylic Resins; Antineoplastic Agents; Cell Survival; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Folic Acid; Folic Acid Transporters; Humans; Imidazoles; Lung Neoplasms; Micelles; Phosphoinositide-3 Kinase Inhibitors; Polyethylene Glycols; Quinolines; Signal Transduction; TOR Serine-Threonine Kinases | 2020 |
Targeting folate receptor β positive tumor-associated macrophages in lung cancer with a folate-modified liposomal complex.
Topics: A549 Cells; Animals; Apoptosis; Cell Proliferation; Folate Receptor 2; Folic Acid; Humans; Liposomes; Lung Neoplasms; Mice; Tumor Microenvironment; Tumor-Associated Macrophages | 2020 |
Fabrication and in vivo evaluation of ligand appended paclitaxel and artemether loaded lipid nanoparticulate systems for the treatment of NSCLC: A nanoparticle assisted combination oncotherapy.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Artemether; Biological Availability; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Folic Acid; Humans; Lipids; Lung Neoplasms; Male; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Polyethylene Glycols; Rats, Sprague-Dawley; Tumor Burden; Xenograft Model Antitumor Assays | 2020 |
Improved Therapeutic Efficacy of Topotecan Against A549 Lung Cancer Cells with Folate-targeted Topotecan Liposomes.
Topics: A549 Cells; Administration, Intravenous; Animals; Cell Survival; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Liposomes; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Polyethylene Glycols; Rats, Sprague-Dawley; Topoisomerase I Inhibitors; Topotecan | 2020 |
Diagnostic and therapeutic evaluation of folate-targeted paclitaxel and vinorelbine encapsulating theranostic liposomes for non-small cell lung cancer.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Folic Acid; Liposomes; Lung Neoplasms; Mice; Mice, Inbred C57BL; Paclitaxel; Precision Medicine; Tissue Distribution; Vinorelbine | 2021 |
Folate Receptor Beta Designates Immunosuppressive Tumor-Associated Myeloid Cells That Can Be Reprogrammed with Folate-Targeted Drugs.
Topics: Adenocarcinoma; Animals; Biomarkers, Tumor; Breast Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Polarity; Cellular Reprogramming Techniques; Cytokines; Folate Receptor 2; Folic Acid; Humans; Immunomodulation; Lung Neoplasms; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myeloid Cells; Myeloid-Derived Suppressor Cells; Tumor Microenvironment; Tumor-Associated Macrophages; Up-Regulation | 2021 |
Methotrexate Gold Nanocarriers: Loading and Release Study: Its Activity in Colon and Lung Cancer Cells.
Topics: A549 Cells; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Colon; Colonic Neoplasms; Drug Delivery Systems; Drug Liberation; Folic Acid; Gold; HCT116 Cells; Humans; Hydrogen-Ion Concentration; Lung; Lung Neoplasms; Metal Nanoparticles; Methotrexate; Tumor Microenvironment | 2020 |
Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines.
Topics: Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choline; Folic Acid; Humans; Lung; Lung Neoplasms; MAP Kinase Signaling System; Methionine; Methylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vitamin B 12 | 2021 |
Paclitaxel-loaded and folic acid-modified PLGA nanomedicine with glutathione response for the treatment of lung cancer.
Topics: Animals; Carcinoma, Lewis Lung; Delayed-Action Preparations; Folic Acid; Glutathione; Lung Neoplasms; Mice; Nanomedicine; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer | 2021 |
Disruption of Cytosolic Folate Integrity Aggravates Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Modulates Metastatic Properties in Non-Small-Cell Lung Cancer Cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Cytoplasm; Drug Resistance, Neoplasm; ErbB Receptors; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mutation; Protein Kinase Inhibitors; Tumor Cells, Cultured | 2021 |
Folic acid phenotype (FAP) is a superior biomarker predicting response to pemetrexed-based chemotherapy in malignant pleural mesothelioma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Middle Aged; Pemetrexed; Peptide Synthases; Phenotype; Pleural Neoplasms; Prognosis; Reduced Folate Carrier Protein; Thymidylate Synthase; Treatment Outcome | 2017 |
Serum folate concentration and the incidence of lung cancer.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Humans; Incidence; Logistic Models; Lung Neoplasms; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors | 2017 |
Chitosan-folate decorated carbon nanotubes for site specific lung cancer delivery.
Topics: Chitosan; Folic Acid; Humans; Lung; Lung Neoplasms; Nanotubes, Carbon | 2017 |
Association of Three Single Nucleotide Polymorphisms in MTR and MTRR Genes with Lung Cancer in a Turkish Population.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alleles; Case-Control Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Lung Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Turkey | 2017 |
FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer.
Topics: A549 Cells; Animals; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Female; Folic Acid; Gene Targeting; Gene Transfer Techniques; Humans; Immunocompetence; Ligands; Lung Neoplasms; Mice; MicroRNAs; Proto-Oncogene Proteins p21(ras); Xenograft Model Antitumor Assays | 2017 |
Doxorubicin-conjugated D-glucosamine- and folate- bi-functionalised InP/ZnS quantum dots for cancer cells imaging and therapy.
Topics: A549 Cells; Cell Line, Tumor; Doxorubicin; Female; Flow Cytometry; Folic Acid; Glucosamine; Humans; Indium; Lung Neoplasms; Ovarian Neoplasms; Phosphines; Quantum Dots; Sulfides; Zinc Compounds | 2018 |
Circulating Folate, Vitamin B6, and Methionine in Relation to Lung Cancer Risk in the Lung Cancer Cohort Consortium (LC3).
Topics: Adult; Aged; Aged, 80 and over; Asia; Australia; Case-Control Studies; Cotinine; Europe; Female; Folic Acid; Humans; Incidence; Lung Neoplasms; Male; Methionine; Middle Aged; Prospective Studies; Protective Factors; Risk Factors; Sex Factors; Smoking; United States; Vitamin B 6 | 2018 |
In vitro and in vivo evaluation of targeting tumor with folate-based amphiphilic multifunctional stabilizer for resveratrol nanosuspensions.
Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Drug Delivery Systems; Drug Stability; Folic Acid; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron; Nanoparticles; Phosphatidylethanolamines; Polyethylene Glycols; Resveratrol; Stilbenes; Suspensions; Xenograft Model Antitumor Assays | 2017 |
The impact of folate intake on the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohort.
Topics: Aged; Cohort Studies; Colorectal Neoplasms; Diet; Early Detection of Cancer; Female; Folic Acid; Food, Fortified; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Ovarian Neoplasms; Prospective Studies; Prostatic Neoplasms; United States | 2018 |
Low-folate stress reprograms cancer stem cell-like potentials and bioenergetics metabolism through activation of mTOR signaling pathway to promote in vitro invasion and in vivo tumorigenicity of lung cancers.
Topics: Animals; Cell Line, Tumor; Cell Movement; Energy Metabolism; Fibroblasts; Folic Acid; Humans; Lung; Lung Neoplasms; Male; Mice, Inbred C57BL; Neoplastic Stem Cells; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2018 |
New Folate-Grafted Chitosan Derivative To Improve Delivery of Paclitaxel-Loaded Solid Lipid Nanoparticles for Lung Tumor Therapy by Inhalation.
Topics: Administration, Inhalation; Albumins; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Compounding; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lipids; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Polyethylene Glycols; Surface Properties; Tissue Distribution; Xenograft Model Antitumor Assays | 2018 |
Intraoperative Molecular Imaging in Lung Cancer: The State of the Art and the Future.
Topics: Adenocarcinoma of Lung; Contrast Media; Folic Acid; Humans; Lung Neoplasms; Molecular Imaging | 2018 |
Paclitaxel controlled delivery using a pH-responsive functional-AuNP/block-copolymer vesicular nanocarrier composite system.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Apoptosis; Caprylates; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Folic Acid; Gold; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Metal Nanoparticles; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polyvinyls; Solubility; Technology, Pharmaceutical; Time Factors | 2018 |
Lung cancer targeted therapy: Folate and transferrin dual targeted, glutathione responsive nanocarriers for the delivery of cisplatin.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Drug Delivery Systems; Drug Liberation; Folic Acid; Glutathione; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Nanoparticles; Prodrugs; Tissue Distribution; Transferrin; Xenograft Model Antitumor Assays | 2018 |
Transferrin and folic acid co-modified bufalin-loaded nanoliposomes: preparation, characterization, and application in anticancer activity.
Topics: A549 Cells; Animals; Antineoplastic Agents; Bufanolides; Cell Death; Diagnostic Imaging; Drug Liberation; Female; Folic Acid; Humans; Inhibitory Concentration 50; Liposomes; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Optical Imaging; Transferrin; Xenograft Model Antitumor Assays | 2018 |
Designing multifunctional cancer-targeted nanosystem for magnetic resonance molecular imaging-guided theranostics of lung cancer.
Topics: A549 Cells; Animals; Antibiotics, Antineoplastic; Cell Survival; Cell-Penetrating Peptides; Doxorubicin; Drug Carriers; Drug Liberation; Folic Acid; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice, Inbred BALB C; Molecular Imaging; Polylactic Acid-Polyglycolic Acid Copolymer; Reactive Oxygen Species; Theranostic Nanomedicine; Xenograft Model Antitumor Assays | 2018 |
Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
Topics: Aminohydrolases; Aminoimidazole Carboxamide; beta Catenin; Carcinogenesis; Cell Line; Cell Line, Tumor; Drug Resistance, Neoplasm; Folic Acid; Gefitinib; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Lung Neoplasms; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multifunctional Enzymes; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Purines; Ribonucleotides | 2019 |
A synergistic approach for management of lung carcinoma through folic acid functionalized co-therapy of capsaicin and gefitinib nanoparticles: Enhanced apoptosis and metalloproteinase-9 down-regulation.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Capsaicin; Cell Survival; Down-Regulation; Drug Delivery Systems; Drug Liberation; Female; Folic Acid; Gefitinib; Humans; Lung Neoplasms; Male; Matrix Metalloproteinase 9; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Rats, Wistar; Urethane | 2019 |
Inhalable dry powder prepared from folic acid-conjugated docetaxel liposomes alters pharmacodynamic and pharmacokinetic properties relevant to lung cancer chemotherapy.
Topics: Administration, Inhalation; Animals; Antineoplastic Agents; Docetaxel; Drug Delivery Systems; Dry Powder Inhalers; Folic Acid; Liposomes; Lung Neoplasms; Male; Particle Size; Powders; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2019 |
Milk exosomes - Natural nanoparticles for siRNA delivery.
Topics: A549 Cells; Animals; Cell Proliferation; Dose-Response Relationship, Drug; ErbB Receptors; Exosomes; Female; Folic Acid; Humans; Lung Neoplasms; Mice; Milk; Proto-Oncogene Proteins p21(ras); RNA, Small Interfering; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2019 |
Food intake of folate, folic acid and other B vitamins with lung cancer risk in a low-income population in the Southeastern United States.
Topics: Adult; Aged; Cohort Studies; Diet; Female; Folic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Poverty; Prospective Studies; Southeastern United States; Vitamin B Complex | 2020 |
The targeting ability of fluorescent quantum dots to the folate receptor rich tumors.
Topics: A549 Cells; Cell Line, Tumor; Folic Acid; Humans; In Vitro Techniques; KB Cells; Lung Neoplasms; Microscopy, Fluorescence; Mouth Neoplasms; Photochemotherapy; Photosensitizing Agents; Quantum Dots | 2019 |
Folate/homocysteine metabolism and lung cancer risk among smokers.
Topics: Age Factors; Aged; Female; Folic Acid; Genotype; Homocysteine; Humans; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Poland; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Reproducibility of Results; Risk Factors; Sex Factors; Smoking | 2019 |
Evaluation of cytotoxic activity of docetaxel loaded gold nanoparticles for lung cancer drug delivery.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Folic Acid; Gold; Humans; Lung Neoplasms; Metal Nanoparticles | 2019 |
A structural equation modelling approach to explore the role of B vitamins and immune markers in lung cancer risk.
Topics: Biomarkers; Folic Acid; Humans; Lung Neoplasms; Male; Methionine; Models, Statistical; Population Surveillance; Prospective Studies; Risk Factors; Vitamin B Complex | 2013 |
Rapid detection of exon 2-deleted AIMP2 mutation as a potential biomarker for lung cancer by molecular beacons.
Topics: Base Sequence; Carrier Proteins; Cell Line, Tumor; Exons; Folic Acid; Humans; Liposomes; Lung; Lung Neoplasms; Nuclear Proteins; Optical Imaging; Real-Time Polymerase Chain Reaction; Sequence Deletion | 2013 |
Drug embedded PVP coated magnetic nanoparticles for targeted killing of breast cancer cells.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Coated Materials, Biocompatible; Drug Delivery Systems; Epirubicin; Female; Folic Acid; Humans; Leukemia; Lung Neoplasms; Magnetite Nanoparticles; Male; Pharmaceutic Aids; Povidone; Prostatic Neoplasms; Spectroscopy, Fourier Transform Infrared | 2013 |
Fabrication of reduced graphene oxide and sliver nanoparticle hybrids for Raman detection of absorbed folic acid: a potential cancer diagnostic probe.
Topics: Adenocarcinoma; Biosensing Techniques; Coated Materials, Biocompatible; Female; Folic Acid; Graphite; HeLa Cells; Humans; Lung Neoplasms; Metal Nanoparticles; Microscopy, Electron, Transmission; Oxides; Silver; Spectrum Analysis, Raman; Uterine Cervical Neoplasms; Vitamin B Complex | 2013 |
Targeted molecular therapy for lung cancer: exuberance reestablished.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation, Preclinical; Female; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms; Male; Neoplasms | 2013 |
Pemetrexed-induced eyelid edema in lung cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Dexamethasone; Diuretics; Edema; Eyelid Diseases; Female; Folic Acid; Furosemide; Glucocorticoids; Glutamates; Guanine; Humans; Lung Neoplasms; Middle Aged; Pemetrexed; Vitamin B 12 | 2013 |
Effect of folic acid and vitamin B12 on pemetrexed antifolate chemotherapy in nutrient lung cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dietary Supplements; Drug Screening Assays, Antitumor; Fluorouracil; Folic Acid; Folic Acid Antagonists; G1 Phase; Glutamates; Guanine; Humans; Lung Neoplasms; Neoplasm Proteins; Pemetrexed; Protein Stability; Serum; Treatment Outcome; Vitamin B 12 | 2013 |
Native American ancestry affects the risk for gene methylation in the lungs of Hispanic smokers from New Mexico.
Topics: Aged; American Indian or Alaska Native; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Diet; DNA Methylation; Female; Folic Acid; Hispanic or Latino; Humans; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; New Mexico; Promoter Regions, Genetic; Risk Factors; Smoking; Sputum | 2013 |
Targeting cancer cells with folic acid-iminoboronate fluorescent conjugates.
Topics: Benzene Derivatives; Boronic Acids; Carcinoma, Non-Small-Cell Lung; Endocytosis; Fluorescent Dyes; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms; Molecular Structure; Muramidase; Tumor Cells, Cultured | 2014 |
Folate-targeted paclitaxel-conjugated polymeric micelles inhibits pulmonary metastatic hepatoma in experimental murine H22 metastasis models.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Emulsions; Female; Folic Acid; Lung Neoplasms; Mice; Mice, Inbred BALB C; Micelles; Molecular Targeted Therapy; Paclitaxel; Polymers; Treatment Outcome | 2014 |
Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation.
Topics: Adenocarcinoma; Administration, Oral; Animals; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Survival; Cofilin 1; Dietary Supplements; Endoplasmic Reticulum; Epithelial-Mesenchymal Transition; Folic Acid; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methylation; Mice, SCID; Neoplasm Transplantation; p21-Activated Kinases; Phosphorylation; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Transport; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Signal Transduction | 2014 |
Association of Graded Folic Acid Supplementation and Total Plasma Homocysteine Levels With Hematological Toxicity During First-line Treatment of Nonsquamous NSCLC Patients With Pemetrexed-based Chemotherapy.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Drug Therapy, Combination; Female; Folic Acid; Hematinics; Homocysteine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Retrospective Studies | 2017 |
Molecular imaging to identify tumor recurrence following chemoradiation in a hostile surgical environment.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Contrast Media; Fluorescein; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms; Mediastinum; Middle Aged; Molecular Imaging; Monitoring, Intraoperative; Neoplasm Recurrence, Local | 2014 |
Plasma homocysteine levels and hematological toxicity in NSCLC patients after the first cycle of pemetrexed under folate supplementation.
Topics: Adult; Aged; Antineoplastic Agents; Blood Platelets; Carcinoma, Non-Small-Cell Lung; Female; Folic Acid; Glutamates; Guanine; Homocysteine; Humans; Leukocytes; Lung Neoplasms; Male; Middle Aged; Pemetrexed | 2015 |
[Safety of pemetrexed according to the duration of vitamin B12 and folic acid supplementation prior to the first dose of pemetrexed].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Diarrhea; Dietary Supplements; Drug Combinations; Exanthema; Female; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Pemetrexed; Retrospective Studies; Vitamin B 12 | 2015 |
Delivery of baicalein and paclitaxel using self-assembled nanoparticles: synergistic antitumor effect in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Neoplasm; Flavanones; Folic Acid; Humans; Hyaluronic Acid; Lung Neoplasms; Mice; Nanomedicine; Nanoparticles; Paclitaxel; Prodrugs; Transfection | 2015 |
Total Plasma Homocysteine Level Assessment and Timing of Folate/B12 Supplementation Prior to Initiation of Pemetrexed-Based Chemotherapy for Nonsquamous Non-Small Cell Lung Cancer Patients: An Irrelevant Investigation, an Unnecessary Delay, or Both?
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Folic Acid; Humans; Lung Neoplasms; Male; Vitamin B 12 | 2015 |
In Reply.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Female; Folic Acid; Humans; Lung Neoplasms; Male; Vitamin B 12 | 2015 |
Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Signal Transduction | 2015 |
New dry powders for inhalation containing temozolomide-based nanomicelles for improved lung cancer therapy.
Topics: Administration, Inhalation; Animals; Antineoplastic Agents; Cell Proliferation; Chemistry, Pharmaceutical; Dacarbazine; Dry Powder Inhalers; Folic Acid; Humans; Lung Neoplasms; Mice; Nanoparticles; Particle Size; Temozolomide | 2015 |
Plasma homocysteine, folate and vitamin B12 levels in patients with lung cancer.
Topics: Adult; Aged; Case-Control Studies; Cell Transformation, Neoplastic; Folic Acid; Homocysteine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Vitamin B 12 | 2015 |
Enhanced antitumor efficacy of folate targeted nanoparticles co-loaded with docetaxel and curcumin.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Curcumin; Docetaxel; Drug Carriers; Folic Acid; HeLa Cells; Humans; Lung Neoplasms; Mice, Inbred C57BL; Nanomedicine; Nanoparticles; Polyesters; Polyethylene Glycols; Sarcoma 180; Solubility; Taxoids; Time Factors; Tumor Burden | 2015 |
Co-delivery of cisplatin and paclitaxel by folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles for the treatment of non-small lung cancer.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Delivery Systems; Folic Acid; Humans; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Nanoparticles; Paclitaxel; Polyesters; Polyethylene Glycols; Tissue Distribution; Treatment Outcome; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Bovine milk-derived exosomes for drug delivery.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Cattle; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Drug Carriers; Exosomes; Female; Folic Acid; Humans; Immune Tolerance; Lung Neoplasms; Male; Mice, Nude; Milk; Nanoparticles; Solubility; Tissue Distribution; Xenograft Model Antitumor Assays | 2016 |
Facile Synthesis of Folic Acid-Modified Iron Oxide Nanoparticles for Targeted MR Imaging in Pulmonary Tumor Xenografts.
Topics: Cell Death; Cell Line, Tumor; Endocytosis; Ferric Compounds; Folic Acid; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Nanoparticles; Particle Size; Tissue Distribution; Xenograft Model Antitumor Assays | 2016 |
Hemocompatibility of folic-acid-conjugated amphiphilic PEG-PLGA copolymer nanoparticles for co-delivery of cisplatin and paclitaxel: treatment effects for non-small-cell lung cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blood; Blood Coagulation; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line; Cisplatin; Complement Activation; Drug Carriers; Drug Compounding; Folic Acid; Hemolysis; Humans; Leukocyte Count; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Polyesters; Polyethylene Glycols; Rabbits; Xenograft Model Antitumor Assays | 2016 |
Enhanced Cytotoxicity of Folic Acid-Targeted Liposomes Co-Loaded with C6 Ceramide and Doxorubicin: In Vitro Evaluation on HeLa, A2780-ADR, and H69-AR Cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Cell Cycle; Ceramides; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; In Vitro Techniques; Liposomes; Lung Neoplasms; Ovarian Neoplasms; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2016 |
Development and evaluation of well-tolerated and tumor-penetrating polymeric micelle-based dry powders for inhaled anti-cancer chemotherapy.
Topics: Administration, Inhalation; Animals; Antineoplastic Agents, Phytogenic; Bronchoalveolar Lavage Fluid; Cell Count; Cell Line, Tumor; Cell Survival; Cytokines; Dextrans; Drug Liberation; Female; Folic Acid; Humans; Leucine; Lung Neoplasms; Mannitol; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Polyethylene Glycols; Powders | 2016 |
Multi-functionalized carbon dots as theranostic nanoagent for gene delivery in lung cancer therapy.
Topics: Animals; Biocompatible Materials; Carbon; Cell Line, Tumor; Disease Models, Animal; Folic Acid; Gene Expression; Gene Silencing; Gene Transfer Techniques; Genes, Reporter; Humans; Imines; Lung Neoplasms; Male; Materials Testing; Mice; Molecular Imaging; Nanoparticles; Oxidation-Reduction; Particle Size; Polyethylenes; RNA, Small Interfering; Theranostic Nanomedicine; Transgenes | 2016 |
Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Large Cell; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Folate Receptor 1; Folic Acid; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neuroendocrine Tumors; Prognosis; Small Cell Lung Carcinoma; Survival Rate; Young Adult | 2016 |
Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Cholesterol; Drug Delivery Systems; ELAV-Like Protein 1; Folate Receptor 1; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Nanoparticles; RNA, Small Interfering; RNAi Therapeutics | 2016 |
Aerosol delivery of folate-decorated hyperbranched polyspermine complexes to suppress lung tumorigenesis via Akt signaling pathway.
Topics: Aerosols; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; DNA; Folic Acid; Folic Acid Transporters; Gene Transfer Techniques; Green Fluorescent Proteins; Humans; Lung Neoplasms; Male; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; Spermine | 2016 |
Nanogold-Gallate Chitosan-Targeted Pulmonary Delivery for Treatment of Lung Cancer.
Topics: Antineoplastic Agents; Biocompatible Materials; Chitosan; Cisplatin; Drug Delivery Systems; Excipients; Folic Acid; Gallic Acid; Gold; Humans; Lung Neoplasms; Metal Nanoparticles | 2017 |
Development and characterization of folic acid-conjugated chitosan nanoparticles for targeted and controlled delivery of gemcitabinein lung cancer therapeutics.
Topics: A549 Cells; Animals; Biological Transport; Chitosan; Delayed-Action Preparations; Deoxycytidine; Drug Carriers; Drug Liberation; Folic Acid; Gemcitabine; Humans; Lung Neoplasms; Mice; Nanoparticles; Particle Size; Polyethylene Glycols; Tissue Distribution | 2017 |
Resveratrol-loaded folic acid-grafted dextran stearate submicron particles exhibits enhanced antitumor efficacy in non-small cell lung cancers.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Caspase 3; Dextrans; Drug Liberation; Folic Acid; Humans; Lung Neoplasms; Mitochondria; Particle Size; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2017 |
Combination Therapy of NSCLC Using Hsp90 Inhibitor and Doxorubicin Carrying Functional Nanoceria.
Topics: A549 Cells; Acrylic Resins; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cerium; Combined Modality Therapy; Doxorubicin; Drug Carriers; Folic Acid; HSP90 Heat-Shock Proteins; Humans; Lung Neoplasms; Nanoparticles; Rats; Reactive Oxygen Species; Triazoles | 2017 |
Pemetrexed single agent chemotherapy in previously treated patients with locally advanced or metastatic non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dexamethasone; Female; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pemetrexed; Vitamin B 12 | 2008 |
[Lung neoplasms--higher risk through vitamin E supplements in combination with smoking].
Topics: Aged; Ascorbic Acid; Chemoprevention; Diet; Dietary Supplements; Female; Folic Acid; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Risk Assessment; Risk Factors; Smoking; Vitamin E; Vitamins | 2008 |
Vitamin supplements and cancer prevention: where do randomized controlled trials stand?
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Colorectal Neoplasms; Confounding Factors, Epidemiologic; Dietary Supplements; Female; Folic Acid; Humans; Incidence; Lung Neoplasms; Male; Neoplasms; Primary Prevention; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Assessment; Selenium; United States; Vitamin B 12; Vitamin B 6; Vitamin E | 2009 |
Tumor cell targeting using folate-conjugated fluorescent quantum dots and receptor-mediated endocytosis.
Topics: Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Endocytosis; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Lung Neoplasms; Microscopy, Atomic Force; Microscopy, Confocal; Microscopy, Electron, Transmission; Polyethylene Glycols; Quantum Dots; Receptors, Cell Surface; Small Cell Lung Carcinoma | 2009 |
Facile synthesis of multivalent folate-block copolymer conjugates via aqueous RAFT polymerization: targeted delivery of siRNA and subsequent gene suppression.
Topics: Acrylamides; Adenocarcinoma; Carrier Proteins; Cations; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Lung Neoplasms; Polymers; Receptors, Cell Surface; RNA, Small Interfering; Tumor Cells, Cultured | 2009 |
Major and prolonged response to pemetrexed in two cases of lung adenocarcinoma with bronchioloalveolar carcinoma features.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Aged; Antimetabolites, Antineoplastic; Bone Neoplasms; Cough; Disease Progression; Dyspnea; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Neoplasm Staging; Neutropenia; Pemetrexed; Remission Induction; Renal Insufficiency; Smoking; Tomography, X-Ray Computed; Vitamin B 12 | 2009 |
Activity of pemetrexed against brain metastases in a patient with adenocarcinoma of the lung.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Brain Neoplasms; Chest Pain; Disease Progression; Dyspnea; Female; Folic Acid; Glutamates; Guanine; Headache; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasm Staging; Pemetrexed; Radiotherapy; Remission Induction; Smoking; Thoracic Surgery; Vitamin B 12 | 2009 |
The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway.
Topics: Administration, Inhalation; Aerosols; Animals; Chitosan; Drug Carriers; Folic Acid; Gene Silencing; Gene Targeting; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Polyethyleneimine; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Treatment Outcome | 2009 |
Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Cadherins; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Core Binding Factor Alpha 3 Subunit; DNA Methylation; Female; Folic Acid; Humans; Immunohistochemistry; Long Interspersed Nucleotide Elements; Lung Neoplasms; Male; Middle Aged | 2009 |
Toxic epidermal necrolysis related to pemetrexed and carboplatin with vitamin B12 and folic acid supplementation for advanced non-small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Pemetrexed; Stevens-Johnson Syndrome; Vitamin B 12 | 2009 |
Source-specific effects of micronutrients in lung cancer prevention.
Topics: Aged; Anticarcinogenic Agents; Ascorbic Acid; beta Carotene; Cohort Studies; Denmark; Diet; Dietary Supplements; Female; Folic Acid; Humans; Lung Neoplasms; Male; Micronutrients; Middle Aged; Proportional Hazards Models; Vitamin E | 2010 |
Case-only gene-environment interaction studies: when does association imply mechanistic interaction?
Topics: Algorithms; Asthma; Data Interpretation, Statistical; Environment; Female; Folic Acid; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Lung Neoplasms; Male; Models, Genetic; Models, Statistical; Polymorphism, Genetic; Research Design; Risk; Smoking | 2010 |
Folate and lung cancer risk.
Topics: Denmark; Diet; Female; Folic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Risk; Vitamin B Complex | 2010 |
Folate conjugated poly(ester amine) for lung cancer therapy.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Folic Acid; Humans; Lung Neoplasms; Macromolecular Substances; Materials Testing; Molecular Conformation; Nanocapsules; Nanomedicine; Polyesters; Surface Properties | 2010 |
Synthesis and in vitro evaluation of defined HPMA folate conjugates: influence of aggregation on folate receptor (FR) mediated cellular uptake.
Topics: Cell Line, Tumor; Cell Survival; Folate Receptor 1; Folic Acid; Humans; In Vitro Techniques; Lung Neoplasms; Magnetic Resonance Spectroscopy; Methacrylates; Nasopharyngeal Neoplasms; Polymerization; Polymers | 2010 |
Variants in folate pathway genes as modulators of genetic instability and lung cancer risk.
Topics: Aged; Case-Control Studies; Female; Ferredoxin-NADP Reductase; Folic Acid; Gene Regulatory Networks; Genetic Predisposition to Disease; Genomic Instability; Glycine Hydroxymethyltransferase; Humans; Linkage Disequilibrium; Lung Neoplasms; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Micronucleus Tests; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Regression Analysis; Tumor Cells, Cultured | 2011 |
MTHFR polymorphisms, folate intake and carcinogen DNA adducts in the lung.
Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Case-Control Studies; DNA Adducts; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Lung; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Staging; Polymorphism, Genetic; Prognosis; Risk Factors; Smoking | 2012 |
Folate-PEG-superparamagnetic iron oxide nanoparticles for lung cancer imaging.
Topics: Animals; Biological Assay; Cell Death; Dextrans; Diagnostic Imaging; Flow Cytometry; Folic Acid; Lung Neoplasms; Magnetic Resonance Spectroscopy; Magnetite Nanoparticles; Male; Mice; Microscopy, Confocal; Nanoparticles; Particle Size; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared; Staining and Labeling | 2012 |
Effects of unconjugated bilirubin on chromosomal damage in individuals with Gilbert's syndrome measured with the micronucleus cytome assay.
Topics: Adult; Aged; Aged, 80 and over; Bilirubin; Chromosome Aberrations; Colorectal Neoplasms; Comet Assay; Cytokinesis; DNA Damage; Endpoint Determination; Female; Folic Acid; Gilbert Disease; Homocysteine; Humans; Lung Neoplasms; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Vitamin B 12; Young Adult | 2012 |
Multicenter trial of EC145 in advanced, folate-receptor positive adenocarcinoma of the lung.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Drug Resistance, Neoplasm; Female; Folate Receptor 1; Folic Acid; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Oligopeptides; Prognosis; Survival Rate; Vinca Alkaloids | 2012 |
Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Folate Receptor 1; Folic Acid; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Tissue Array Analysis | 2013 |
Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Survival; Dendrimers; Folic Acid; Gold; Humans; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Tomography, X-Ray Computed | 2013 |
Pemetrexed for previously treated patients with non-small cell lung cancer and differences in efficacy according to thymidylate synthase expression.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Folic Acid; Glutamates; Guanine; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nausea; Neutropenia; Pemetrexed; Salvage Therapy; Thrombocytopenia; Thymidylate Synthase; Treatment Outcome | 2012 |
Intakes of fruits, vegetables, and related vitamins and lung cancer risk: results from the Shanghai Men's Health Study (2002-2009).
Topics: Adult; Aged; Ascorbic Acid; Carotenoids; China; Cohort Studies; Eating; Folic Acid; Follow-Up Studies; Fruit; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Risk Factors; Vegetables; Vitamin A; Vitamins | 2013 |
Investigating multiple candidate genes and nutrients in the folate metabolism pathway to detect genetic and nutritional risk factors for lung cancer.
Topics: Aged; Alcohol Drinking; Bayes Theorem; Betaine; Case-Control Studies; Choline; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Vitamin B Complex | 2013 |
Serum carotenoids and mortality from lung cancer: a case-control study nested in the Japan Collaborative Cohort (JACC) study.
Topics: Adult; Aged; Alcohol Drinking; Anticarcinogenic Agents; Antioxidants; beta Carotene; Body Mass Index; Canthaxanthin; Carotenoids; Case-Control Studies; Cholesterol; Cohort Studies; Cryptoxanthins; Feeding Behavior; Female; Folic Acid; Follow-Up Studies; Humans; Japan; Life Style; Lung Neoplasms; Lutein; Lycopene; Male; Middle Aged; Odds Ratio; Smoking; Tocopherols; Vitamin A; Xanthophylls | 2003 |
[On the value of the urinary folic acid excretion test for diagnosis of malignant disease].
Topics: Body Fluids; Folic Acid; Humans; Lung Neoplasms; Neoplasms | 1963 |
THE CHEMOTHERAPY OF CANCER WITH MASSIVE DOSES UNDER THE PROTECTION OF PERFUSION OF AUTOGENOUS HEMATOPOIETIC TISSUE.
Topics: Adenine; Bone Marrow Transplantation; Breast Neoplasms; DNA; Female; Folic Acid; Humans; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Melphalan; Neoplasms; Ovarian Neoplasms; Perfusion; Sarcoma; Thiotepa; Triethylenemelamine | 1964 |
Dietary folate intake and lung cancer risk in former smokers: a case-control analysis.
Topics: Aged; Case-Control Studies; Diet; Female; Folic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Regression Analysis; Risk Factors; Smoking; Smoking Cessation | 2003 |
Iron oxide nanoparticles as magnetic resonance contrast agent for tumor imaging via folate receptor-targeted delivery.
Topics: Animals; Carrier Proteins; Coated Materials, Biocompatible; Contrast Media; Dextrans; Disease Models, Animal; Endocytosis; Ferric Compounds; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Lung Neoplasms; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Nanostructures; Nasopharyngeal Neoplasms; Plasma Substitutes; Radiographic Image Enhancement; Receptors, Cell Surface; Sensitivity and Specificity; Tissue Distribution; Tumor Cells, Cultured | 2004 |
Polymorphisms in folate metabolic genes and lung cancer risk in Xuan Wei, China.
Topics: Adult; Aged; Alleles; China; Cystathionine beta-Synthase; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genetic Variation; Haplotypes; Homozygote; Humans; Lung Neoplasms; Male; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk; Smoking | 2005 |
Lung cancer mortality and serum levels of carotenoids, retinol, tocopherols, and folic acid in men and women: a case-control study nested in the JACC Study.
Topics: Adult; Aged; Antioxidants; Carotenoids; Case-Control Studies; Cohort Studies; Female; Folic Acid; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Nutritional Status; Sex Factors; Surveys and Questionnaires; Tocopherols; Vitamin A | 2005 |
Pemetrexed: a new cytotoxic agent in the development for first-line non-small-cell lung cancer.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase III as Topic; Dietary Supplements; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Lung Neoplasms; Pemetrexed; Vitamin B 12 | 2005 |
BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.
Topics: Animals; Apoptosis; Biological Transport; Carrier Proteins; Cell Proliferation; Choriocarcinoma; Enzyme Inhibitors; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Idoxuridine; Iodine Radioisotopes; Leukemia L1210; Lung Neoplasms; Membrane Transport Proteins; Mice; Mice, Nude; Ovarian Neoplasms; Quinazolines; Receptors, Cell Surface; Reduced Folate Carrier Protein; Thymidylate Synthase; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured | 2005 |
Intrinsic cisplatin resistance in lung and ovarian cancer cells propagating in medium acutely depleted of folate.
Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Cisplatin; Culture Media; DNA Methylation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Profiling; Humans; Inhibitory Concentration 50; Lung Neoplasms; Microarray Analysis; Ovarian Neoplasms | 2006 |
Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case control study.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoma, Large Cell; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Japan; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Random Allocation; Risk Factors | 2007 |
Prognostic significance of folate metabolism polymorphisms for lung cancer.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Enzymes; Female; Folic Acid; Genotype; Humans; Lung Neoplasms; Metabolic Networks and Pathways; Polymorphism, Single Nucleotide; Prognosis | 2007 |
Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.
Topics: Adenocarcinoma; Animals; Binding, Competitive; Blood Proteins; Carrier Proteins; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Protein Binding; Pterins; Receptors, Cell Surface; Time Factors; Tumor Burden; Vinca Alkaloids; Xenograft Model Antitumor Assays | 2007 |
[Folate-poly-L-lysine-Gd-DTPA as MR contrast agent for tumor imaging via folate receptor-targeted delivery].
Topics: Animals; Carrier Proteins; Contrast Media; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Gadolinium DTPA; Humans; Lung Neoplasms; Lysine; Magnetic Resonance Imaging; Mice; Mice, Nude; Neoplasms, Experimental; Receptors, Cell Surface; Reproducibility of Results; Sensitivity and Specificity; Transplantation, Heterologous | 2007 |
Commentary: a case for minimizing folate supplementation in clinical regimens with pemetrexed based on the marked sensitivity of the drug to folate availability.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Colorectal Neoplasms; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; In Vitro Techniques; Lung Neoplasms; Mesothelioma; Pemetrexed; Tetrahydrofolates | 2007 |
Long-term use of supplemental multivitamins, vitamin C, vitamin E, and folate does not reduce the risk of lung cancer.
Topics: Aged; Ascorbic Acid; Chemoprevention; Diet; Dietary Supplements; Female; Folic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Vitamin E; Vitamins | 2008 |
Immunologic heterogeneity of the folate-binding proteins from chronic myelogenous leukemia cells and myelofibrosis spleen.
Topics: Antigen-Antibody Complex; Binding, Competitive; Carrier Proteins; Colon; Folate Receptors, GPI-Anchored; Folic Acid; Hepatitis; Humans; Immune Sera; Kinetics; Leukemia, Myeloid; Lung; Lung Neoplasms; Primary Myelofibrosis; Radioimmunoassay; Receptors, Cell Surface; Spleen; Uremia | 1981 |
Effect of antioxidants and antitoxicants of isoniazid on the formation of lung tumours in mice by isoniazid and hydrazine sulphate.
Topics: Animals; Antioxidants; Arginine; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Folic Acid; Hydrazines; Isoniazid; Lung Neoplasms; Mice; Neoplasms, Experimental; Pyridoxine; Sodium Glutamate | 1982 |
Prevention of isoniazid tumorigenicity by antitoxicants of isoniazid in Swiss mice.
Topics: Adenocarcinoma; Ammonia; Animals; Arginine; Folic Acid; Isoniazid; Kidney; Liver; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Protein Biosynthesis; Pyridoxine; Sodium Glutamate | 1980 |
New anti-lung-cancer antibody cluster 12 reacts with human folate receptors present on adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Blotting, Western; Breast Neoplasms; Bronchi; Carcinoma, Small Cell; Carrier Proteins; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Hybridomas; Immunoglobulin G; Immunohistochemistry; Lung Neoplasms; Mice; Mice, Inbred BALB C; Organ Specificity; Receptors, Cell Surface | 1994 |
Markedly induced asialoGM1+CD8+ T cell production and enhancement of antimetastatic activity by interferon beta with folic or folinic acid.
Topics: Animals; Antineoplastic Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Drug Combinations; Folic Acid; G(M1) Ganglioside; Interferon-beta; Leucovorin; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Peritoneal Cavity | 1997 |
Cigarette smoking, serum lipids, folate, and vitamin B12 in lung cancer.
Topics: Adolescent; Adult; Aged; Cholesterol; Female; Folic Acid; Humans; Lipids; Lipoproteins, HDL; Lung Neoplasms; Male; Middle Aged; Nicotiana; Plants, Toxic; Smoking; Time Factors; Triglycerides; Turkey; Vitamin B 12 | 1996 |
A cross-sectional study of vitamin intake in postoperative non-small cell lung cancer patients.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Cross-Sectional Studies; Dietary Supplements; Disease-Free Survival; Erythrocytes; Female; Folic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Pneumonectomy; Postoperative Care; Vitamin A | 1998 |
Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5,4,6][1,4]thiazin -6-yl)-(S)-ethyl]-2,5-thienoylamino-L-glutamic acid (AG
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Drug Resistance, Multiple; Drug Synergism; Folic Acid; Folic Acid Antagonists; Glutamates; Head and Neck Neoplasms; Humans; Hydroxymethyl and Formyl Transferases; Kinetics; Lung Neoplasms; Phosphoribosylglycinamide Formyltransferase; Pyrimidines; Trimetrexate; Tumor Cells, Cultured | 1999 |
A prospective cohort study on antioxidant and folate intake and male lung cancer risk.
Topics: Aged; Antioxidants; Case-Control Studies; Cohort Studies; Diet; Folic Acid; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Risk Assessment; Smoking | 2000 |
Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Colonic Neoplasms; Fluorouracil; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leucovorin; Lung Neoplasms; Membrane Proteins; Membrane Transport Proteins; Mice; Multienzyme Complexes; Neoplasms; Peptide Synthases; Reduced Folate Carrier Protein; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured | 2000 |
Localized folate and vitamin B-12 deficiency in squamous cell lung cancer is associated with global DNA hypomethylation.
Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; DNA Methylation; Folic Acid; Folic Acid Deficiency; Humans; Lung Neoplasms; Middle Aged; Smoking; Statistics as Topic; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Colorful cancer prevention: alpha-carotene, lycopene, and lung cancer.
Topics: Carotenoids; Edible Grain; Feeding Behavior; Folic Acid; Fruit; Humans; Lung Neoplasms; Lutein; Lycopene; Nutrition Policy; Smoking; Vegetables | 2000 |
In vitro effects of folic acid on gamma-glutamyltransferase and glutathione reductase activities in malignant lung and thymus tumors.
Topics: Dose-Response Relationship, Drug; Folic Acid; gamma-Glutamyltransferase; Glutathione Reductase; Hamartoma; Humans; In Vitro Techniques; Lung Neoplasms; Reference Values; Thymoma; Thymus Neoplasms; Tuberculoma | 2000 |
Polymorphisms of methylene-tetrahydrofolate reductase and risk of lung cancer: a case-control study.
Topics: Aged; Case-Control Studies; Diet; Female; Folic Acid; Humans; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors | 2001 |
Folate status among patients with non-small cell lung cancer: a case-control study.
Topics: Aged; Alcohol Drinking; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Diet; Female; Folic Acid; Homocystine; Humans; Lung Neoplasms; Male; Postoperative Period; Risk Factors; Smoking | 2001 |
10-formyltetrahydrofolate dehydrogenase, one of the major folate enzymes, is down-regulated in tumor tissues and possesses suppressor effects on cancer cells.
Topics: Adenocarcinoma; Cell Division; Cell Line, Transformed; Down-Regulation; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Liver Regeneration; Lung Neoplasms; Male; Oxidoreductases Acting on CH-NH Group Donors; Prostatic Neoplasms; RNA, Messenger; Tumor Cells, Cultured | 2002 |
Carcinogenicity of nitrosation products of ephedrine, sarcosine, folic acid, and creatinine.
Topics: Adenoma, Bile Duct; Animals; Carcinogens; Carcinoma; Creatinine; Ephedrine; Folic Acid; Hyperplasia; Lethal Dose 50; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Neurofibroma; Nitro Compounds; Nitroso Compounds; Precancerous Conditions; Sarcosine | 1975 |
[Malignant juvenile bone tumors].
Topics: Adolescent; Adult; Aged; Amputation, Surgical; Bone Neoplasms; Child; Diagnosis, Differential; Doxorubicin; Drug Therapy, Combination; Eosinophilic Granuloma; Female; Folic Acid; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Osteomyelitis; Osteosarcoma; Sarcoma, Ewing | 1978 |
[Prophylaxis of complications caused by cytostatic drugs used in oncological patients].
Topics: Adolescent; Adult; Antineoplastic Agents; Breast Neoplasms; Child; Chlorides; Diazepam; Female; Folic Acid; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Pyridoxine | 1979 |
Cytokinetic chemotherapy design for the treatment of advanced lung cancer.
Topics: Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Folic Acid; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis | 1979 |
Mechanism of cell death following thymidylate synthase inhibition: 2'-deoxyuridine-5'-triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole.
Topics: Cell Division; Cell Survival; Deoxyuracil Nucleotides; Dipyridamole; DNA Damage; Drug Synergism; Folic Acid; Humans; Lung Neoplasms; Quinazolines; Thymidine; Thymidylate Synthase; Time Factors; Tumor Cells, Cultured | 1991 |
Epidemiological screening for potentially carcinogenic drugs.
Topics: Barbiturates; Breast Neoplasms; Carcinogens; Diazepam; Dose-Response Relationship, Drug; Erythromycin; Folic Acid; Humans; Information Systems; Lung Neoplasms; Multiple Myeloma; Neoplasms; Product Surveillance, Postmarketing; Vitamin E | 1990 |
Vegetable consumption and lung cancer risk: a population-based case-control study in Hawaii.
Topics: Ascorbic Acid; beta Carotene; Carotenoids; Dietary Fiber; Epidemiologic Methods; Female; Folic Acid; Hawaii; Humans; Lung Neoplasms; Male; Risk; Smoking; Vegetables; Vitamin A | 1989 |
Screening prescription drugs for possible carcinogenicity: eleven to fifteen years of follow-up.
Topics: Anti-Bacterial Agents; Atropa belladonna; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Erythromycin; Esophageal Neoplasms; Folic Acid; Follow-Up Studies; Gastrointestinal Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neomycin; Neoplasms; Phenylbutazone; Piperidones; Plants, Medicinal; Plants, Toxic; Polymyxin B; Propantheline; Secobarbital; Sulfathiazoles; Vitamins | 1989 |
The quantitation by radioimmunoassay of 2'-deoxyuridine 5'-triphosphate in extracts of thymidylate synthase-inhibited cells.
Topics: Antineoplastic Agents; Cell Line; Cross Reactions; Deoxyuracil Nucleotides; Folic Acid; Humans; Immune Sera; Lung Neoplasms; Quinazolines; Radioimmunoassay; Thymidylate Synthase; Tumor Cells, Cultured | 1989 |
Potentiation of quinazoline antifolate (CB3717) toxicity by dipyridamole in human lung carcinoma, A549, cells.
Topics: Carcinoma; Cell Survival; Dipyridamole; DNA; Drug Synergism; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Quinazolines; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured | 1988 |
Effects of anticancer drugs on folate disposition and excretion.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Folic Acid; Liver; Lung Neoplasms; Male; Methotrexate; Mice | 1985 |
[Method of selective protection of the gastrointestinal tract in the methotrexate treatment of trophoblastic tumors].
Topics: Administration, Oral; Adult; Charcoal; Choriocarcinoma; Digestive System; Drug Combinations; Female; Folic Acid; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms; Vaginal Neoplasms | 1973 |
Small intestinal function in malignant neoplasia.
Topics: Adult; Aged; Biopsy; Celiac Disease; Feces; Female; Folic Acid; Gastrointestinal Neoplasms; Humans; Immunoglobulin A; Intestine, Small; Jejunum; Lung Neoplasms; Lymphatic Metastasis; Malabsorption Syndromes; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Schilling Test; Sulfobromophthalein; Tritium; Xylose | 1972 |
[On the value of the use of the urinary folic acid elimination test in the differential diagnosis of cancerous pulmonary diseases].
Topics: Folic Acid; Humans; Lung Neoplasms; Urine | 1965 |
Clinical and experimental evaluation of urinary histidine derivatives as an index of folic acid metabolism. II. The observation in neoplastic diseases with or without methotrexate administration.
Topics: Adult; Aged; Animals; Blood Cell Count; Blood Platelets; Dogs; Female; FIGLU Test; Folic Acid; Histidine; Humans; Leukocyte Count; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasms | 1969 |