folic acid has been researched along with Cancer of Head in 38 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (15.79) | 18.7374 |
1990's | 4 (10.53) | 18.2507 |
2000's | 10 (26.32) | 29.6817 |
2010's | 16 (42.11) | 24.3611 |
2020's | 2 (5.26) | 2.80 |
Authors | Studies |
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Batista Arantes, LMR; De Castro, TB; Galbiatti-Dias, ALS; Maniglia, JV; Maria Goloni Bertollo, E; Oliveira-Cucolo, JG; Pavarino, EC; Raposo, LS; Rodrigues-Fleming, GH; Silva, FP; Silva, JNGD | 1 |
Bharadwaj, R; Medhi, S | 1 |
Xu, L; Yang, H; Yeudall, WA | 1 |
Dong, S; Ju, Z; Yang, J | 1 |
Cheng, Z; Ding, X; Fan, C; Su, J; Yu, S; Zhang, S | 1 |
Buys, SS; Gren, LH; Hashibe, M; Kawakita, D; La Vecchia, C; Lee, YA | 1 |
Xu, L; Yang, H | 1 |
Arantes, LM; da Silva, JN; de Castro, TB; Galbiatti, AL; Goloni-Bertollo, EM; Maniglia, JV; Pavarino, EC; Raposo, LS; Succi, M | 1 |
Apollo, A; Cox, L; Fury, MG; Haque, S; Ho, AL; Lipson, BL; Lyo, JK; Pfister, DG; Sales, R; Seetharamu, N; Sherman, EJ; Sima, CS; Xiao, H | 1 |
Bazi, A; Garme, Y; Khosravi, A; Miri-Moghaddam, E; Motazedian, J; Saravani, S | 1 |
Kittrell, S; Xu, L; Yang, H; Yeudall, WA | 1 |
Bossi, P; Licitra, L; Locati, LD; Tagliabue, E | 1 |
Chen, Z; Cho, K; Müller, S; Nie, S; Saba, NF; Shin, DM; Tighiouart, M; Wang, X | 1 |
Chen, ZG; Cho, KJ; Giannakakou, P; Gjyrezi, A; Kim, G; Koenig, L; Li, J; Nie, S; Shin, DM; Shin, HJ; Tighiouart, M; Wang, X; Wang, Y | 1 |
Hanai, N; Hasegawa, Y; Hosono, S; Ito, H; Kawakita, D; Matsuo, K; Murakami, S; Oze, I; Sato, F; Tajima, K; Tanaka, H; Watanabe, M; Yatabe, Y | 1 |
da Silva, LM; Galbiatti, AL; Goloni-Bertollo, EM; Maniglia, JV; Pavarino, EC; Raposo, LS; Ruiz, MT | 1 |
Hasegawa, Y; Hosono, S; Ito, H; La Vecchia, C; Matsuo, K; Negri, E; Oze, I; Rossi, M; Tajima, K; Tanaka, H; Watanabe, M; Yatabe, Y | 1 |
Chen, RC; Copp, JA; Cox, AD; Cummings, ND; Karve, S; Li, C; Napier, ME; Sukumar, R; Wang, AZ; Werner, ME | 1 |
da Silva, LM; Galbiatti, AL; Goloni-Bertollo, EM; Maníglia, JV; Pavarino, EC; Raposo, LS; Ruiz-Cintra, MT | 1 |
Galbiatti, AL; Goloni-Bertollo, EM; Maniglia, JV; Pavarino-Bertelli, EC; Raposo, LS; Ruiz, MT | 1 |
Chasman, DI; Ridker, PM; Rose, L; Zee, RY | 1 |
Frick, B; Fuchs, D; Schröcksnadel, K | 1 |
DALY, JF; SULLIVAN, RD | 1 |
SULLIVAN, RD | 1 |
Almadori, G; Bussu, F; Cadoni, G; Galli, J; Giardina, B; Maurizi, M; Minucci, A; Persichilli, S; Zappacosta, B | 1 |
Kane, MA | 1 |
Hsiung, D; Kelsey, KT; Kraunz, KS; Liu, M; McClean, MD; Nelson, HH; Osanyingbemi, J | 1 |
Hasegawa, Y; Hiraki, A; Hirose, K; Matsuo, K; Saito, T; Sato, S; Suzuki, T; Tajima, K; Ueda, R; Wakai, K | 1 |
Chabner, BA; Clendeninn, NJ; Cowan, KH; Curt, GA; Jolivet, J | 1 |
Capizzi, RL; George, T; Kamen, BA; McGuirt, F; Schifeling, DJ | 1 |
Chéradame, S; Dassonville, O; Demard, F; Etienne, MC; Formento, P; Milano, G; Schneider, M | 1 |
Faessel, HM; Greco, WR; Rustum, YM; Slocum, HK | 1 |
Backus, HH; Jansen, G; Molders, N; Padrón, JM; Peters, GJ; Pinedo, HM; van Der Wilt, CL; van Groeningen, CJ; Wouters, D | 1 |
Almadori, G; Bussu, F; Cadoni, G; Galli, J; Giardina, B; Minucci, A; Persichilli, S; Zappacosta, B | 1 |
Snow, GB; van der Vijgh, WJ; Versluis, RJ | 1 |
Hordijk, GJ; Jansen, G; Kathmann, GA; Schornagel, JH; van der Laan, BF; Westerhof, GR | 1 |
Hartenstein, RC; Rohloff, R; Trott, KR; Wendt, TG; Wustrow, TP | 1 |
Advani, SH; Agarwal, RK; Damle, SR; Gokhale, SV; Pai, VR; Redkar, SL; Roy, RK; Shetty, PA | 1 |
4 review(s) available for folic acid and Cancer of Head
Article | Year |
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Association between folate intake and risk of head and neck squamous cell carcinoma: An overall and dose-response PRISMA meta-analysis.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Diet; Dose-Response Relationship, Drug; Eating; Female; Folic Acid; Folic Acid Deficiency; Head and Neck Neoplasms; Humans; Male; Middle Aged; Observational Studies as Topic; Odds Ratio; Risk Factors; Squamous Cell Carcinoma of Head and Neck | 2017 |
Head and neck cancer: genetic polymorphisms and folate metabolism.
Topics: DNA Methylation; Folic Acid; Genotype; Head and Neck Neoplasms; Humans; Polymorphism, Genetic | 2012 |
The role of folates in squamous cell carcinoma of the head and neck.
Topics: Alcohol Drinking; Carcinoma, Squamous Cell; Chemoprevention; Folic Acid; Folic Acid Deficiency; Head and Neck Neoplasms; Humans; Risk Factors; Smoking | 2005 |
The pharmacology and clinical use of methotrexate.
Topics: Administration, Oral; Animals; Biological Transport; Central Nervous System; Drug Resistance; Folic Acid; Folic Acid Antagonists; Gene Amplification; Head and Neck Neoplasms; Humans; Kinetics; Leucovorin; Leukemia, Lymphoid; Lung Neoplasms; Methotrexate; Neoplasms; Osteoma, Osteoid; Thymidylate Synthase; Tissue Distribution | 1983 |
1 trial(s) available for folic acid and Cancer of Head
Article | Year |
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A phase II study of pralatrexate with vitamin B12 and folic acid supplementation for previously treated recurrent and/or metastatic head and neck squamous cell cancer.
Topics: Adult; Aged; Aminopterin; Carcinoma, Squamous Cell; Disease Progression; Female; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck; Vitamin B 12; Vitamin B Complex; Young Adult | 2014 |
33 other study(ies) available for folic acid and Cancer of Head
Article | Year |
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Gene Polymorphisms Involved in Folate Metabolism and DNA Methylation with the Risk of Head and Neck Cancer.
Topics: Biomarkers, Tumor; Brazil; Case-Control Studies; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Female; Folic Acid; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Promoter Regions, Genetic; Risk Factors; Survival Rate; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 2020 |
Effectual nanotherapy against oral squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Carriers; Folic Acid; Head and Neck Neoplasms; Mouth Neoplasms; Nanoparticles; Paclitaxel; Squamous Cell Carcinoma of Head and Neck; Tissue Distribution | 2021 |
Folic acid-decorated polyamidoamine dendrimer exhibits high tumor uptake and sustained highly localized retention in solid tumors: Its utility for local siRNA delivery.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Dendrimers; Female; Folic Acid; Gene Transfer Techniques; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Proteins; Neovascularization, Pathologic; Polyamines; RNA, Small Interfering; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2017 |
Cisplatin and paclitaxel co-delivered by folate-decorated lipid carriers for the treatment of head and neck cancer.
Topics: Animals; Cell Line, Tumor; Cisplatin; Drug Carriers; Folic Acid; Head and Neck Neoplasms; Lipids; Mice; Paclitaxel | 2016 |
The impact of folate intake on the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian cancer screening trial (PLCO) cohort.
Topics: Aged; Cohort Studies; Colorectal Neoplasms; Diet; Early Detection of Cancer; Female; Folic Acid; Food, Fortified; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Ovarian Neoplasms; Prospective Studies; Prostatic Neoplasms; United States | 2018 |
Folate-Decorated Polyamidoamine Dendrimer Nanoparticles for Head and Neck Cancer Gene Therapy.
Topics: Animals; Cell Line, Tumor; Dendrimers; Folic Acid; Gene Transfer Techniques; Genetic Therapy; Head and Neck Neoplasms; Heterografts; Humans; Mice; Nanoparticles; Polyamines; RNA, Small Interfering | 2019 |
DNMT3B C46359T and SHMT1 C1420T polymorphisms in the folate pathway in carcinogenesis of head and neck.
Topics: Adult; Aged; Alcohol Drinking; Brazil; Carcinogenesis; Case-Control Studies; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Female; Folic Acid; Genetic Association Studies; Genotype; Glycine Hydroxymethyltransferase; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Risk Factors; Smoking | 2014 |
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms in oral squamous cell carcinoma in south-east Iran.
Topics: Adult; Aged; Alleles; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; Head and Neck Neoplasms; Humans; Iran; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mouth Neoplasms; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Factors; Squamous Cell Carcinoma of Head and Neck | 2016 |
Folic acid-decorated polyamidoamine dendrimer mediates selective uptake and high expression of genes in head and neck cancer cells.
Topics: Cell Line, Tumor; Cell Survival; Dendrimers; Folate Receptor 1; Folic Acid; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Plasmids; Polyamines; Transfection | 2016 |
Folate in head and neck squamous cell cancer chemoprevention: purposely left out?
Topics: Carcinoma, Squamous Cell; Chemoprevention; Folic Acid; Folic Acid Deficiency; Head and Neck Neoplasms; Humans; Risk Assessment; Sensitivity and Specificity | 2008 |
Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lymphatic Metastasis; Male; Middle Aged; Nanomedicine; Nanotechnology; Paclitaxel; Receptors, Cell Surface; Young Adult | 2009 |
HFT-T, a targeting nanoparticle, enhances specific delivery of paclitaxel to folate receptor-positive tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Carrier Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Carriers; Female; Folate Receptors, GPI-Anchored; Folic Acid; Head and Neck Neoplasms; Heparin; Humans; Mice; Microtubules; Nanomedicine; Nanoparticles; Paclitaxel; Particle Size; Receptors, Cell Surface; Tissue Distribution | 2009 |
Association between dietary folate intake and clinical outcome in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cohort Studies; Diet; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Middle Aged; Minor Histocompatibility Antigens; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Surveys and Questionnaires; Thymidylate Synthase; Young Adult | 2012 |
MTHFD1 G1958A, BHMT G742A, TC2 C776G and TC2 A67G polymorphisms and head and neck squamous cell carcinoma risk.
Topics: Betaine-Homocysteine S-Methyltransferase; Brazil; Carcinoma, Squamous Cell; DNA Methylation; Female; Folic Acid; Genomic Instability; Head and Neck Neoplasms; Humans; Logistic Models; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Transcobalamins | 2012 |
Folate, alcohol, and aldehyde dehydrogenase 2 polymorphism and the risk of oral and pharyngeal cancer in Japanese.
Topics: Adult; Aged; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Asian People; Carcinoma; Carcinoma, Squamous Cell; Case-Control Studies; Eating; Female; Folic Acid; Gene-Environment Interaction; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mouth Neoplasms; Pharyngeal Neoplasms; Polymorphism, Single Nucleotide; Risk Factors; Squamous Cell Carcinoma of Head and Neck; Young Adult | 2012 |
Folate-targeted polymeric nanoparticle formulation of docetaxel is an effective molecularly targeted radiosensitizer with efficacy dependent on the timing of radiotherapy.
Topics: Animals; Biological Transport; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Docetaxel; Folic Acid; Folic Acid Transporters; Head and Neck Neoplasms; Humans; KB Cells; Mice; Molecular Targeted Therapy; Nanoparticles; Polymers; Radiation-Sensitizing Agents; Taxoids; Time Factors; Xenograft Model Antitumor Assays | 2011 |
Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk.
Topics: Aged; Alleles; Carcinoma, Squamous Cell; Case-Control Studies; DNA Methylation; Female; Folic Acid; Gene Deletion; Genotype; Head and Neck Neoplasms; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Statistical; Polymorphism, Genetic; Regression Analysis; Risk; Squamous Cell Carcinoma of Head and Neck; Time Factors; Treatment Outcome | 2012 |
Genetic variation of fifteen folate metabolic pathway associated gene loci and the risk of incident head and neck carcinoma: the Women's Genome Health Study.
Topics: Female; Folic Acid; Genetic Loci; Genetic Variation; Genome, Human; Haplotypes; Head and Neck Neoplasms; Health Surveys; Humans; Metabolic Networks and Pathways; Middle Aged; Polymorphism, Single Nucleotide; Regression Analysis; Risk Factors | 2013 |
Serum folate and homocysteine levels in head and neck squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Disease Progression; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Hyperhomocysteinemia; Neopterin; Prognosis; Risk Factors | 2002 |
The treatment of head and neck cancer with the continuous arterial infusion of methotrexate and the intermittent intramuscular administration of citrovorum factor.
Topics: Arteries; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Injections, Intramuscular; Leucovorin; Methotrexate | 1961 |
Continuous arterial infusion of methotrexate with intermittent, intramuscular citrovorum factor therapy in head and neck cancer.
Topics: Arteries; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Injections, Intramuscular; Leucovorin; Methotrexate | 1961 |
Serum levels of folate, homocysteine, and vitamin B12 in head and neck squamous cell carcinoma and in laryngeal leukoplakia.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Laryngeal Neoplasms; Leukoplakia; Male; Middle Aged; Prognosis; Reference Values; Risk Assessment; Sensitivity and Specificity; Vitamin B 12 | 2005 |
Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Diet; DNA Methylation; Female; Folic Acid; Genotype; Head and Neck Neoplasms; Humans; Male; Methylation; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors | 2006 |
One-carbon metabolism-related gene polymorphisms and risk of head and neck squamous cell carcinoma: case-control study.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aged; Alcohol Drinking; Carbon; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Random Allocation; Risk Factors; Thymidylate Synthase | 2007 |
Methotrexate content in squamous cell carcinoma of the head and neck after low-dose methotrexate.
Topics: Administration, Oral; Adult; Carcinoma, Squamous Cell; Female; Folic Acid; Head and Neck Neoplasms; Humans; Injections, Intramuscular; Male; Methotrexate; Middle Aged; Mucous Membrane | 1994 |
Tumoral-reduced folates and clinical resistance to fluorouracil-based treatment in head and neck cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Female; Fluorouracil; Folic Acid; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Staging; Remission Induction | 1997 |
Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5,4,6][1,4]thiazin -6-yl)-(S)-ethyl]-2,5-thienoylamino-L-glutamic acid (AG
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Drug Resistance, Multiple; Drug Synergism; Folic Acid; Folic Acid Antagonists; Glutamates; Head and Neck Neoplasms; Humans; Hydroxymethyl and Formyl Transferases; Kinetics; Lung Neoplasms; Phosphoribosylglycinamide Formyltransferase; Pyrimidines; Trimetrexate; Tumor Cells, Cultured | 1999 |
Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Colonic Neoplasms; Fluorouracil; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leucovorin; Lung Neoplasms; Membrane Proteins; Membrane Transport Proteins; Mice; Multienzyme Complexes; Neoplasms; Peptide Synthases; Reduced Folate Carrier Protein; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured | 2000 |
Serum folate and homocysteine levels in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Progression; Female; Folic Acid; Head and Neck Neoplasms; Homocysteine; Humans; Male; Middle Aged; Risk Factors; Smoking | 2002 |
[Blood and urinary methotrexate determinations in patients with squamous cell carcinoma of the head and neck area].
Topics: Carcinoma, Squamous Cell; Clinical Enzyme Tests; Drug Therapy, Combination; Folic Acid; Head and Neck Neoplasms; Humans; Methotrexate; Radioimmunoassay | 1979 |
In vitro activity of novel antifolates against human squamous carcinoma cell lines of the head and neck with inherent resistance to methotrexate.
Topics: Aminopterin; Biological Transport; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tumor Cells, Cultured | 1992 |
Accelerated split-course radiotherapy and simultaneous cis-dichlorodiammine-platinum and 5-fluorouracil chemotherapy with folinic acid enhancement for unresectable carcinoma of the head and neck.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; Female; Fluorouracil; Folic Acid; Follow-Up Studies; Gamma Rays; Head and Neck Neoplasms; Humans; Male; Middle Aged; Radiotherapy Planning, Computer-Assisted | 1987 |
Serum folate level before & after methotrexate administration & its relation to the toxic manifestations.
Topics: Asparaginase; Folic Acid; Head and Neck Neoplasms; Humans; Leucovorin; Methotrexate | 1987 |