Page last updated: 2024-08-17

folic acid and Cancer of Gastrointestinal Tract

folic acid has been researched along with Cancer of Gastrointestinal Tract in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19905 (17.86)18.7374
1990's2 (7.14)18.2507
2000's10 (35.71)29.6817
2010's7 (25.00)24.3611
2020's4 (14.29)2.80

Authors

AuthorsStudies
Arthur, RS; Brasky, TM; Hays, J; Loomans-Kropp, HA; Navarro, SL; Neuhouser, ML; Newton, AM; Ray, RM; Schenk, JM; Snetselaar, LG1
Iimura, Y; Kanemoto, Y; Kuroda, S; Kurokawa, T; Nojima, M; Tsurita, G; Yazawa, K1
Alizadeh, BZ; Dastgiri, S; de Bock, GH; Dolatkhah, R; Moazzen, S1
Arai, T; Chijimatsu, R; Doki, Y; Eguchi, H; Hirotsu, T; Ishii, H; Kitagawa, T; Ofusa, K; Takeda, Y; Vecchione, A; Yabumoto, M1
Angelini, S; Bermejo, JL; Biasco, G; Casali, PG; Consolini, N; Fumagalli, E; Hrelia, P; Musti, M; Nannini, M; Palassini, E; Pantaleo, MA; Ravegnini, G; Venturoli, N1
Imai, K; Tsurita, G; Yasui, H1
Cui, W; Guo, Y; Wen, X; Wu, W; Zhang, D1
Asai, A; Doki, Y; Ishii, H; Kawamoto, K; Konno, M; Mori, M; Nishida, N; Satoh, T1
Stover, PJ1
Jin, XF; Liu, Q; Ran, ZH; Tong, JL; Xiao, SD; Xu, Q; Xu, XT; Yang, CH1
Cai, J; Li, Q; Ling, Y; Ng, KM; Qiu, T; Shan, L; Su, X; Wang, J; Wang, L; Ying, J; Zhao, H1
Ali, S; Haq, S; Mohammad, R; Sarkar, FH1
Höffken, K; Kliche, KO; Kubsch, K; Masri-Zada, R; Raida, M1
Hu, Y; Jin, G; Li, R; Mason, J; Qian, Z; Russell, R; Shi, Y; Sohg, H; Wahg, M; Wu, G; Xia, D; Xiao, S; Xie, Y; Zhang, L; Zhou, Y; Zhu, S1
Fang, JY; Xiao, SD1
Azam, M; Hassan, M; Hazir, T; Krishin, J; Nisar, YB; Rehman, SU1
Omura, K1
Giovannucci, E; Larsson, SC; Wolk, A1
Li, H; Lin, D; Miao, X; Tan, W; Wang, L1
Alvarez-Cabellos, R; Garcia-Carbonero, R; Garcia-Lacalle, C; Gomez, P; Paz-Ares, L; Sanchez, D; Tercero, A1
Deng, L; Knock, E; Lawrance, AK; Rozen, R; Wang, XL; Wu, Q1
Allegra, CJ1
Kim, YI; Mason, JB1
Bratseva, VL1
Ambrosetti, A; Bambara, LM; Corrocher, R; De Sandre, G; Hoffbrand, AV; Pachor, ML1
Fireman, BH; Friedman, GD; Selby, JV1
Bessot, M; Duprez, A; Fays, J; Mauuary, G1
McGREGOR McGregor, RF; Nelson, RS; Somayaji, BN1

Reviews

10 review(s) available for folic acid and Cancer of Gastrointestinal Tract

ArticleYear
Impact of One-Carbon Metabolism-Driving Epitranscriptome as a Therapeutic Target for Gastrointestinal Cancer.
    International journal of molecular sciences, 2021, Jul-06, Volume: 22, Issue:14

    Topics: Animals; Carbon; Cell Transformation, Neoplastic; Folic Acid; Gastrointestinal Neoplasms; Humans; Methylation; Mitochondria; Reactive Oxygen Species; RNA

2021
DNA synthesis inhibitors for the treatment of gastrointestinal cancer.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:16

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Coordination Complexes; Cytidine; Drug Delivery Systems; Folic Acid; Gastrointestinal Neoplasms; Humans; Nanostructures; Nucleic Acid Synthesis Inhibitors; Organoplatinum Compounds; Platinum Compounds; Pyrimidines; Thymidine

2014
Elevated homocysteine level and folate deficiency associated with increased overall risk of carcinogenesis: meta-analysis of 83 case-control studies involving 35,758 individuals.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Adult; Carcinoma; Case-Control Studies; Female; Folic Acid; Folic Acid Deficiency; Gastrointestinal Neoplasms; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Urologic Neoplasms

2015
The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review).
    International journal of oncology, 2017, Volume: 50, Issue:4

    Topics: Aminohydrolases; Antineoplastic Agents; Fluorouracil; Folic Acid; Folic Acid Antagonists; Gastrointestinal Neoplasms; Glycine Hydroxymethyltransferase; Humans; Metabolic Networks and Pathways; Metabolome; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); MicroRNAs; Mitochondria; Molecular Targeted Therapy; Multienzyme Complexes; Nucleosides; Nucleotides; Oxidoreductases Acting on CH-NH Group Donors; Purines; Reactive Oxygen Species; Serine

2017
The complexities of epidemiology and prevention of gastrointestinal cancers.
    International journal of molecular sciences, 2012, Oct-01, Volume: 13, Issue:10

    Topics: Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Diabetes Complications; Folic Acid; Gastrointestinal Neoplasms; Humans; Hypoglycemic Agents; Inflammatory Bowel Diseases; Metformin; Obesity; Pancreatic Neoplasms; Smoking

2012
Folic acid, polymorphism of methyl-group metabolism genes, and DNA methylation in relation to GI carcinogenesis.
    Journal of gastroenterology, 2003, Volume: 38, Issue:9

    Topics: DNA Methylation; Folic Acid; Gastrointestinal Neoplasms; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic

2003
[Specialized nutrition support for the patients with advanced or recurrent carcinoma of the gastrointestinal tract].
    Nihon Geka Gakkai zasshi, 2004, Volume: 105, Issue:2

    Topics: Enteral Nutrition; Folic Acid; Folic Acid Deficiency; Gastrointestinal Neoplasms; Humans; Neoplasm Recurrence, Local; Nutrition Assessment; Nutrition Disorders; Nutritional Support; Vitamin B 12; Vitamin B 12 Deficiency

2004
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
    Gastroenterology, 2006, Volume: 131, Issue:4

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Case-Control Studies; Esophageal Neoplasms; Folic Acid; Gastrointestinal Neoplasms; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Pancreatic Neoplasms; Polymorphism, Genetic; Risk Factors; Stomach Neoplasms

2006
Genetic polymorphisms in folate- metabolizing enzymes and risk of gastroesophageal cancers: a potential nutrient-gene interaction in cancer development.
    Forum of nutrition, 2007, Volume: 60

    Topics: Carbon-Nitrogen Ligases; China; Esophageal Neoplasms; Folic Acid; Folic Acid Deficiency; Gastrointestinal Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Polymorphism, Genetic; Risk Factors; Thymidylate Synthase

2007
Nutrition chemoprevention of gastrointestinal cancers: a critical review.
    Nutrition reviews, 1996, Volume: 54, Issue:9

    Topics: American Cancer Society; Antioxidants; Calcium; Chemoprevention; Dietary Fiber; Fatty Acids, Omega-3; Folic Acid; Gastrointestinal Neoplasms; Guidelines as Topic; Humans; National Institutes of Health (U.S.); Nutritional Physiological Phenomena; Selenium; United States; Vitamin D

1996

Trials

3 trial(s) available for folic acid and Cancer of Gastrointestinal Tract

ArticleYear
Chronomodulated chemotherapy in metastatic gastrointestinal cancer combining 5-FU and sodium folinate with oxaliplatin, irinotecan or gemcitabine: the Jena experience in 79 patients.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Camptothecin; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Folic Acid; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Stomach Neoplasms

2002
The effect of folic acid on the development of stomach and other gastrointestinal cancers.
    Chinese medical journal, 2003, Volume: 116, Issue:1

    Topics: Adult; Aged; Anticarcinogenic Agents; beta Carotene; Double-Blind Method; Female; Folic Acid; Gastric Mucosa; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Patient Compliance; Stomach Neoplasms

2003
Fluorouracil-based chemotherapy in patients with gastrointestinal malignancies: influence of nutritional folate status on toxicity.
    Journal of chemotherapy (Florence, Italy), 2007, Volume: 19, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Folic Acid; Gastrointestinal Neoplasms; Homocysteine; Humans; Male; Middle Aged; Vitamin B 12

2007

Other Studies

15 other study(ies) available for folic acid and Cancer of Gastrointestinal Tract

ArticleYear
Supplemental B-Vitamins and Risk of Upper Gastrointestinal Cancers in the Women's Health Initiative.
    Nutrition and cancer, 2023, Volume: 75, Issue:4

    Topics: Aged; Female; Folic Acid; Gastrointestinal Neoplasms; Humans; Middle Aged; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Women's Health

2023
Potential thiamine deficiency and neurological symptoms in patients receiving chemotherapy for gastrointestinal cancer.
    International journal of clinical pharmacology and therapeutics, 2020, Volume: 58, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; Fluorouracil; Folic Acid; Gastrointestinal Neoplasms; Humans; Male; Middle Aged; Nervous System Diseases; Retrospective Studies; Risk Factors; Sodium; Thiamine; Thiamine Deficiency; Vitamin B 12; Young Adult

2020
Staple Food Fortification with Folic Acid and Iron and Gastrointestinal Cancers: Critical Appraisal of Long-Term National Fortification.
    Nutrition and cancer, 2021, Volume: 73, Issue:8

    Topics: Aged; Esophageal Neoplasms; Flour; Folic Acid; Food, Fortified; Gastrointestinal Neoplasms; Humans; Iron; Middle Aged; Stomach Neoplasms; Triticum

2021
Folate-related polymorphisms in gastrointestinal stromal tumours: susceptibility and correlation with tumour characteristics and clinical outcome.
    European journal of human genetics : EJHG, 2015, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Folic Acid; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Polymorphism, Genetic

2015
One-carbon metabolism-genome interactions in folate-associated pathologies.
    The Journal of nutrition, 2009, Volume: 139, Issue:12

    Topics: Animals; Carbon; Child; Developmental Disabilities; Disease Models, Animal; Environment; Folic Acid; Gastrointestinal Neoplasms; Genetic Phenomena; Genome, Human; Homocysteine; Humans; Methionine; Mice; Neural Tube Defects; Purines; Risk Factors; Thymidine Monophosphate

2009
Chemopreventive effect of epigallocatechin-3-gallate (EGCG) and folic acid on the N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastrointestinal cancer in rat model.
    Journal of digestive diseases, 2011, Volume: 12, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Folic Acid; Gastrointestinal Neoplasms; Hematinics; Male; Methylnitronitrosoguanidine; Rats; Rats, Wistar; Sarcoma; Treatment Outcome

2011
Frequent epigenetic silencing of the folate-metabolising gene cystathionine-beta-synthase in gastrointestinal cancer.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Cell Line, Tumor; Colorectal Neoplasms; Cystathionine beta-Synthase; DNA Methylation; Down-Regulation; Folic Acid; Gastrointestinal Neoplasms; Gene Silencing; Humans; Mutation; Neoplasm Metastasis; Neoplasm Staging; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Stomach Neoplasms

2012
Blue rubber bleb nevus syndrome: associated with severe GI bleeding requiring one hundred blood transfusions.
    JPMA. The Journal of the Pakistan Medical Association, 2003, Volume: 53, Issue:11

    Topics: Anemia, Iron-Deficiency; Blood Transfusion; Child; Diagnosis, Differential; Female; Folic Acid; Gastrointestinal Hemorrhage; Gastrointestinal Neoplasms; Hemangioma; Humans; Iron; Nevus, Blue; Skin Neoplasms; Syndrome

2003
Strain differences in mice highlight the role of DNA damage in neoplasia induced by low dietary folate.
    The Journal of nutrition, 2008, Volume: 138, Issue:4

    Topics: Animals; Betaine; Diet; DNA Damage; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Genotype; Homocysteine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; RNA, Messenger; Thymine Nucleotides; Uridine Triphosphate

2008
New therapeutic strategies for patients with gastrointestinal malignancies using biochemical modulation of fluorouracil.
    JAMA, 1995, Jan-18, Volume: 273, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Colonic Neoplasms; Fatal Outcome; Fluorouracil; Folic Acid; Folic Acid Antagonists; Gastrointestinal Neoplasms; Gene Expression Regulation, Enzymologic; Humans; Interferon-alpha; Leucovorin; Liver Neoplasms; Male; Middle Aged; Prognosis; Quinazolines; RNA, Messenger; RNA, Neoplasm; Thymidylate Synthase

1995
[Prophylaxis of complications caused by cytostatic drugs used in oncological patients].
    Vrachebnoe delo, 1979, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents; Breast Neoplasms; Child; Chlorides; Diazepam; Female; Folic Acid; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Pyridoxine

1979
Specific and non-specific folate binding protein in normal and malignant human tissues.
    Journal of clinical pathology, 1978, Volume: 31, Issue:7

    Topics: Adolescent; Adult; Aged; Carrier Proteins; Female; Folic Acid; Gastrointestinal Neoplasms; Humans; Intestinal Mucosa; Leukemia; Leukocytes; Male; Middle Aged

1978
Screening prescription drugs for possible carcinogenicity: eleven to fifteen years of follow-up.
    Cancer research, 1989, Oct-15, Volume: 49, Issue:20

    Topics: Anti-Bacterial Agents; Atropa belladonna; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Erythromycin; Esophageal Neoplasms; Folic Acid; Follow-Up Studies; Gastrointestinal Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neomycin; Neoplasms; Phenylbutazone; Piperidones; Plants, Medicinal; Plants, Toxic; Polymyxin B; Propantheline; Secobarbital; Sulfathiazoles; Vitamins

1989
[Regional and sequential chemotherapy of digestive cancer].
    Acta chirurgica Belgica, 1971, Volume: 70, Issue:4

    Topics: Angiography; Antineoplastic Agents; Folic Acid; Follow-Up Studies; Gastrointestinal Neoplasms; Humans; Injections, Intra-Arterial; Methotrexate; Mitomycins; Rectal Neoplasms; Stomach Neoplasms; Thiotepa; Vinblastine

1971
Small intestinal function in malignant neoplasia.
    Cancer, 1972, Volume: 29, Issue:5

    Topics: Adult; Aged; Biopsy; Celiac Disease; Feces; Female; Folic Acid; Gastrointestinal Neoplasms; Humans; Immunoglobulin A; Intestine, Small; Jejunum; Lung Neoplasms; Lymphatic Metastasis; Malabsorption Syndromes; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Schilling Test; Sulfobromophthalein; Tritium; Xylose

1972