folic acid has been researched along with Bipolar Disorder in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (13.33) | 18.7374 |
| 1990's | 7 (15.56) | 18.2507 |
| 2000's | 10 (22.22) | 29.6817 |
| 2010's | 20 (44.44) | 24.3611 |
| 2020's | 2 (4.44) | 2.80 |
| Authors | Studies |
|---|---|
| Doery, JC; Galletly, C; Griffin, RC; Lam, NSK; Li, X; Lim, F; Long, XX; Saad, M | 1 |
| Chou, LS; Hsieh, YC; Li, DJ; Lin, CH; Tseng, PT; Wu, HC | 1 |
| Huang, X; Li, W; Lu, XB; Ning, YP; Qi, H; Sim, K; Ungvari, GS; Xiang, YT; Xiao, L; Zheng, W | 1 |
| Attenburrow, MJ; Gardiner, A; Geddes, JR; Goodwin, GM; Harrison, PJ; Hinds, C; Rendell, JM; Tunbridge, EM | 1 |
| Baldessarini, RJ; Patel, N; Viguera, AC | 1 |
| Agartz, I; Andreassen, OA; Berg, AO; Gurholt, TP; Jørgensen, KN; Lonning, V; Melle, I; Nerhus, M; Osnes, K | 1 |
| Gardiner, A; Geddes, JR; Goodwin, GM; Mayer, S; Rendell, J; Simon, J | 1 |
| Razzouk, D | 1 |
| Cohen, M; Cruz, L; Miguel, S; Silva Lima, AFBD | 1 |
| Akbaş, H; Cinemre, B; Doğanavşargil Baysal, GÖ; Gökmen, Z; Karaman, T; Metin, Ö | 1 |
| Bartkowska-Sniatkowska, A; Chlopocka-Wozniak, M; Dorszewska, J; Permoda-Osip, A; Rybakowski, JK | 1 |
| Baek, JH; Bernstein, EE; Nierenberg, AA | 1 |
| Chlopocka-Wozniak, M; Dorszewska, J; Permoda-Osip, A; Rybakowski, JK; Skibinska, M | 1 |
| Brutsche, NE; Ionescu, DF; Luckenbaugh, DA; Lundin, NB; Machado-Vieira, R; Niciu, MJ; Richards, EM; Vande Voort, JL; Zarate, CA | 1 |
| Cowen, PJ; Geddes, JR; Hockney, R; McPeake, L; Sharpley, AL | 1 |
| Attenburrow, MJ; Gardiner, A; Geddes, JR; Goodwin, GM; Hainsworth, J; Harrison, PJ; Hinds, C; Rendell, J; Simon, J; Tunbridge, E; Voysey, M; Yu, LM | 1 |
| Fava, M; Freeman, MP; Mischoulon, D; Zajecka, J | 1 |
| Aydin, M; Kara, I; Kilic, G; Kucukali, CI; Orhan, N; Ozbek, Z; Ozkok, E; Sazci, A | 1 |
| Andreazza, AC; Brissos, S; Cardoso, C; Dias, VV; Kapczinski, F | 1 |
| Almeida, J; Corrêa, BB; da Silva, JA; dos Santos, A; Gago, J; Xavier, M | 1 |
| Demirhan, O; Sertdemir, Y; Tastemir, D | 1 |
| Asadi, S; Behzadi, AH; Chalian, M; Ghadiri, M; Omrani, Z | 1 |
| Brocardo, PS; Budni, J; Dafre, AL; Franco, JL; Pavesi, E; Rodrigues, AL; Terenzi, MG; Trevisan, R; Uliano-Silva, M | 1 |
| Bouslama, A; Douki, W; Ezzaher, A; Gaha, L; Mechri, A; Mouhamed, DH; Najjar, MF; Neffati, F; Omezzine, A | 1 |
| Davis, JM; Torrey, EF | 1 |
| Bly, MJ; Brook, RD; Dalack, G; Ellingrod, VL; Grove, TB; Pop-Busui, R; Taylor, SF; Zöllner, SK | 1 |
| Deckersbach, T; Nierenberg, AA; Peters, AT; Sylvia, LG | 1 |
| Kafantaris, V; Saito, E; Tsivkin, R | 1 |
| Belmaker, RH; Bersudsky, Y; Osher, Y; Sela, BA; Silver, H | 1 |
| Morris, DW; Rush, AJ; Trivedi, MH | 1 |
| Abou-Saleh, MT; Coppen, A | 1 |
| Agrawal, SS; Kushwaha, MR; Prakash, R; Sethi, BB; Sethi, N | 1 |
| McLaughlin, B; McMahon, A | 1 |
| Fröscher, W; Laage, M; Maier, V; Straub, R; Wolfersdorf, M | 1 |
| Hasanah, CI; Khan, UA; Musalmah, M; Razali, SM | 1 |
| Reid, SD | 1 |
| Brooks, SC; Disney, N; Linn, JJ | 1 |
| Chen, CN; Chow, CC; Lee, S; Shek, CC; Wing, YK | 1 |
| McKeon, P; O'Broin, J; O'Regan, S; Shelley, R | 1 |
| Bottiglieri, T; Carney, MW; Chanarin, I; Chary, TK; Laundy, M; Reynolds, EH; Toone, B | 1 |
| Bell, IR; Cole, JO; Dreier, T; Edman, JS; Liptzin, B; Marby, DW; Satlin, A | 1 |
| Alarcon, RD; Kemp, B; Monti, JA; Morere, DA; Smythies, JR; Tolbert, LC; Walter-Ryan, WG | 1 |
| Brandt, JT; Hurley, RS; Smeltzer, DJ; Stagno, SJ; Stern, MG; Stern, SL | 1 |
| Kanamura, H; Kurihare, M; Machiyama, Y; Nakamura, T; Otsuka, T; Takahashi, R; Utena, H | 1 |
7 review(s) available for folic acid and Bipolar Disorder
| Article | Year |
|---|---|
The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review.
Topics: Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Bipolar Disorder; Depressive Disorder, Major; Female; Folic Acid; Humans | 2022 |
Serum folate levels in bipolar disorder: a systematic review and meta-analysis.
Topics: Bipolar Disorder; Female; Folic Acid; Humans; Male; Nutritional Status | 2019 |
Adjunctive folate for major mental disorders: A systematic review.
Topics: Antipsychotic Agents; Bipolar Disorder; Depressive Disorder, Major; Folic Acid; Humans; Schizophrenia | 2020 |
One-carbon metabolism and bipolar disorder.
Topics: Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Brain; Folic Acid; Humans; Lamotrigine; Methylenetetrahydrofolate Reductase (NADPH2); Triazines; Valproic Acid | 2013 |
Adjunct treatments for schizophrenia and bipolar disorder: what to try when you are out of ideas.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aspirin; Benzothiazoles; Bipolar Disorder; Celecoxib; Chemotherapy, Adjuvant; Cyclooxygenase 2 Inhibitors; Dopamine Agonists; Estrogens; Fatty Acids, Omega-3; Folic Acid; Humans; Mianserin; Minocycline; Mirtazapine; Pramipexole; Pregnenolone; Pyrazoles; Randomized Controlled Trials as Topic; Schizophrenia; Sulfonamides; Treatment Outcome; Vitamin B Complex | 2012 |
Nutrient-based therapies for bipolar disorder: a systematic review.
Topics: Antidepressive Agents, Second-Generation; Bipolar Disorder; Choline; Chromium; Dietary Supplements; Fatty Acids, Omega-3; Folic Acid; Humans; Inositol; Lipotropic Agents; Magnesium; Trace Elements; Tryptophan; Vitamin B Complex | 2013 |
Folate and unipolar depression.
Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder, Major; Drug Therapy, Combination; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Treatment Outcome | 2008 |
6 trial(s) available for folic acid and Bipolar Disorder
| Article | Year |
|---|---|
Biochemical and genetic predictors and correlates of response to lamotrigine and folic acid in bipolar depression: Analysis of the CEQUEL clinical trial.
Topics: Adult; Bipolar Disorder; Brief Psychiatric Rating Scale; Catechol O-Methyltransferase; Double-Blind Method; Drug Combinations; Female; Folic Acid; Humans; Lamotrigine; Male; Pharmacogenomic Testing; Psychotropic Drugs; Quetiapine Fumarate; Treatment Outcome; Triazines | 2017 |
Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy (and folic acid vs placebo) in patients with bipolar depression (CEQUEL).
Topics: Antipsychotic Agents; Bipolar Disorder; Cost-Benefit Analysis; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Humans; Lamotrigine; Male; Placebos; Quality of Life; Quality-Adjusted Life Years; Quetiapine Fumarate; Treatment Outcome | 2018 |
Vitamin B12 level may be related to the efficacy of single ketamine infusion in bipolar depression.
Topics: Adult; Aged; Bipolar Disorder; Excitatory Amino Acid Antagonists; Female; Folic Acid; Homocysteine; Humans; Infusions, Intravenous; Ketamine; Male; Middle Aged; Vitamin B 12 | 2013 |
Folic acid supplementation for prevention of mood disorders in young people at familial risk: a randomised, double blind, placebo controlled trial.
Topics: Bipolar Disorder; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Incidence; Male; Risk | 2014 |
Comparative evaluation of quetiapine plus lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in bipolar depression (CEQUEL): a 2 × 2 factorial randomised trial.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Humans; Lamotrigine; Male; Middle Aged; Quetiapine Fumarate; Treatment Outcome; Triazines | 2016 |
Folic acid efficacy as an alternative drug added to sodium valproate in the treatment of acute phase of mania in bipolar disorder: a double-blind randomized controlled trial.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Adult; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Drug Administration Schedule; Folic Acid; Humans; Placebos; Severity of Illness Index; Treatment Outcome; Valproic Acid | 2009 |
32 other study(ies) available for folic acid and Bipolar Disorder
| Article | Year |
|---|---|
Mood-Stabilizing Anticonvulsants, Spina Bifida, and Folate Supplementation: Commentary.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Dietary Supplements; Female; Folic Acid; Humans; Lamotrigine; Neural Tube Defects; Pregnancy; Pregnancy Complications; Spinal Dysraphism; Triazines; Valproic Acid | 2018 |
Vitamin D, Folate and the Intracranial Volume in Schizophrenia and Bipolar Disorder and Healthy Controls.
Topics: Adult; Bipolar Disorder; Brain; Case-Control Studies; Female; Folic Acid; Humans; Linear Models; Magnetic Resonance Imaging; Male; Schizophrenia; Vitamin D; Young Adult | 2018 |
Commentary on Simon et al. 2018: "Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy (and folic acid vs placebo) in patients with bipolar depression (CEQUEL)".
Topics: Antipsychotic Agents; Bipolar Disorder; Cost-Benefit Analysis; Folic Acid; Humans; Lamotrigine; Quetiapine Fumarate | 2019 |
Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy(and folic acid vs placebo) in patients with bipolar depression (CEQUEL).
Topics: Antipsychotic Agents; Bipolar Disorder; Cost-Benefit Analysis; Folic Acid; Humans; Lamotrigine; Quetiapine Fumarate | 2019 |
[Association of serum homocysteine and methionine levels with cognition and functioning in bipolar disorder].
Topics: Bipolar Disorder; Case-Control Studies; Cognition; Folic Acid; Homocysteine; Humans; Methionine; Psychiatric Status Rating Scales; Severity of Illness Index; Vitamin B 12 | 2013 |
Hyperhomocysteinemia in bipolar depression: clinical and biochemical correlates.
Topics: Adult; Aged; Biomarkers; Bipolar Disorder; E-Selectin; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Intercellular Adhesion Molecule-1; Male; Middle Aged; Vitamin B 12; Young Adult | 2013 |
Baseline vitamin B12 and folate levels do not predict improvement in depression after a single infusion of ketamine.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Bipolar Disorder; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Female; Folic Acid; Humans; Ketamine; Male; Middle Aged; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Treatment Outcome; Vitamin B 12 | 2014 |
Does folic acid interfere with lamotrigine?
Topics: Antipsychotic Agents; Bipolar Disorder; Folic Acid; Humans; Lamotrigine; Quetiapine Fumarate; Triazines | 2016 |
Effect of the methylenetetrahydrofolate reductase gene polymorphisms on homocysteine, folate and vitamin B12 in patients with bipolar disorder and relatives.
Topics: Adult; Analysis of Variance; Bipolar Disorder; Family; Female; Fluorescence Polarization Immunoassay; Folic Acid; Gene Frequency; Genotype; Homocystine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Vitamin B 12 | 2008 |
Serum homocysteine levels and cognitive functioning in euthymic bipolar patients.
Topics: Adult; Age Factors; Bipolar Disorder; Cognition Disorders; Demography; Diagnostic and Statistical Manual of Mental Disorders; Dysthymic Disorder; Female; Folic Acid; Homocysteine; Humans; Male; Neuropsychological Tests; Severity of Illness Index; Sex Factors; Vitamin B 12 | 2009 |
Bipolar disorder, homocysteine and white matter hyperintensities.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Brain; Female; Folic Acid; Haloperidol; Homocystine; Humans; Lithium Carbonate; Magnetic Resonance Imaging; Middle Aged; Neuropsychological Tests; Vitamin B 12 | 2008 |
The expression of folate sensitive fragile sites in patients with bipolar disorder.
Topics: Adolescent; Adult; Bipolar Disorder; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Cytogenetics; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Young Adult | 2009 |
Folic acid administration prevents ouabain-induced hyperlocomotion and alterations in oxidative stress markers in the rat brain.
Topics: Animals; Antimanic Agents; Biomarkers; Bipolar Disorder; Disease Models, Animal; Folic Acid; Hippocampus; Injections, Intraventricular; Lithium Chloride; Male; Motor Activity; Ouabain; Oxidative Stress; Rats; Rats, Wistar | 2010 |
Hyperhomocysteinemia in Tunisian bipolar I patients.
Topics: Adult; Bipolar Disorder; Case-Control Studies; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Dehydrogenase (NAD+); Middle Aged; Odds Ratio; Polymorphism, Genetic; Tunisia; Vitamin B 12 | 2011 |
Risk factors associated with metabolic syndrome in bipolar and schizophrenia subjects treated with antipsychotics: the role of folate pharmacogenetics.
Topics: Adult; Age Factors; Antipsychotic Agents; Bipolar Disorder; Catechol O-Methyltransferase; Cross-Sectional Studies; Female; Folic Acid; Genetic Variation; Homocysteine; Humans; Life Style; Male; Metabolic Syndrome; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Pharmacogenetics; Risk Factors; Schizophrenia; Smoking | 2012 |
Some antipsychotics' effect on suicide; duloxetine's promise for elderly.
Topics: Aged; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Duloxetine Hydrochloride; Folic Acid; Humans; Suicide Prevention; Thiophenes; United States | 2004 |
Macrocytosis associated with divalproex treatment.
Topics: Anemia, Macrocytic; Anticonvulsants; Bipolar Disorder; Child; Dose-Response Relationship, Drug; Erythrocyte Indices; Female; Folic Acid; Follow-Up Studies; Humans; Platelet Count; Thrombocytopenia; Valproic Acid; Vitamin B 12 | 2005 |
Neuropsychological correlates of homocysteine levels in euthymic bipolar patients.
Topics: Adolescent; Adult; Bipolar Disorder; Cognition; Cognition Disorders; Dysthymic Disorder; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neuropsychological Tests; Severity of Illness Index; Vitamin B 12 | 2008 |
Plasma folate and affective morbidity during long-term lithium therapy.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Female; Folic Acid; Humans; Lithium; Male; Middle Aged; Time Factors | 1982 |
A case report of megaloblastic anemia secondary to lithium.
Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Sideroblastic; Bipolar Disorder; Folic Acid; Humans; Lithium; Male | 1981 |
Folate and depression.
Topics: Bipolar Disorder; Depressive Disorder; Diagnostic Tests, Routine; Erythrocytes; Folic Acid; Folic Acid Deficiency; Humans | 1993 |
[Folic acid deficiency in patients hospitalized with depression? A pilot study of clinical relevance].
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Erythrocytes; Feeding Behavior; Female; Folic Acid; Folic Acid Deficiency; Hospitalization; Humans; Male; Middle Aged; Pilot Projects; Reference Values | 1993 |
Reduced red-cell folate in mania.
Topics: Adult; Bipolar Disorder; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Hospitalization; Humans; Male; Psychiatric Status Rating Scales; Socioeconomic Factors | 1997 |
Pseudodementia in a twenty-one-year-old with bipolar disorder and vitamin B12 and folate deficiency.
Topics: Adult; Bipolar Disorder; Dementia; Female; Folic Acid; Folic Acid Deficiency; Humans; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Serotonin, folic acid, and uric acid metabolism in the diagnosis of neuropsychiatric disorders.
Topics: Adolescent; Adult; Bipolar Disorder; Brain; Carbolines; Female; Folic Acid; Hallucinations; Humans; Male; Mental Disorders; Middle Aged; Neurotic Disorders; Personality Disorders; Schizophrenia; Schizophrenia, Catatonic; Schizophrenia, Childhood; Serotonin; Suicide; Uric Acid | 1978 |
Folate concentration in Chinese psychiatric outpatients on long-term lithium treatment.
Topics: Ambulatory Care; Bipolar Disorder; China; Feeding Behavior; Female; Folic Acid; Folic Acid Deficiency; Hong Kong; Humans; Lithium; Long-Term Care; Male; Mental Disorders; Mental Health Services | 1992 |
Serum and red cell folate and affective morbidity in lithium prophylaxis.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depressive Disorder; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Recurrence | 1991 |
Red cell folate concentrations in psychiatric patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcoholism; Bipolar Disorder; Depressive Disorder; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Mental Disorders; Middle Aged; Schizophrenia; Vitamin B 12 | 1990 |
Vitamin B12 and folate status in acute geropsychiatric inpatients: affective and cognitive characteristics of a vitamin nondeficient population.
Topics: Affective Disorders, Psychotic; Aged; Aged, 80 and over; Bipolar Disorder; Cognition Disorders; Depressive Disorder; Female; Folic Acid; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Neurocognitive Disorders; Retrospective Studies; Vitamin B 12 | 1990 |
One-carbon metabolism disturbances in affective disorders. A preliminary report.
Topics: Bipolar Disorder; Depressive Disorder; Erythrocytes; Folic Acid; Humans; Kinetics; Methionine Adenosyltransferase; Phosphatidylcholines; S-Adenosylmethionine; Schizophrenia; Transferases | 1985 |
Serum and red cell folate concentrations in outpatients receiving lithium carbonate.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Erythrocytes; Female; Folic Acid; Humans; Lithium; Lithium Carbonate; Male; Middle Aged; Recurrence | 1988 |
Tyrosine metabolism in manic depressive illness.
Topics: Adult; Aged; Ascorbic Acid; Bipolar Disorder; Diet; Female; Folic Acid; Humans; Male; Middle Aged; Pyridoxine; Tyrosine | 1968 |