folic acid has been researched along with Benign Neoplasms in 1035 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 156 (15.07) | 18.7374 |
| 1990's | 56 (5.41) | 18.2507 |
| 2000's | 185 (17.87) | 29.6817 |
| 2010's | 472 (45.60) | 24.3611 |
| 2020's | 166 (16.04) | 2.80 |
| Authors | Studies |
|---|---|
| Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L | 1 |
| de Vries, RH; Geersing, A; Jansen, G; Roelfes, G; Rots, MG | 1 |
| Deng, R; Dong, L; Du, Y; Feng, J; Li, K; Wang, D; Wen, D; Zhang, H | 1 |
| Dao, TP; Doan, P; Doan, VD; Nguyen, BT; Nguyen, DT; Nguyen, VT; Plavskii, V; Tran, NQ | 1 |
| Araya, E; Cordero, ML; Hassan, N; Juárez, J; Kogan, MJ; Orellana, N; Palma, S; Ruso, JM; Topete, A; Torres, E; Vasquez-Contreras, R; Vio, V | 1 |
| Ao, J; Liu, AA; Lv, C; Pang, DW; Tang, M; Wang, J | 1 |
| Abdalla, MS; Abdelhamed, RE; Abdelwahab, TS; Ali, EN; Mansour, NA | 1 |
| Al-Nemrawi, NK; Altawabeyeh, RM; Darweesh, RS | 1 |
| Asare-Addo, K; Ebrahimnejad, P; Nokhodchi, A; Sodagar Taleghani, A | 1 |
| Ghergurovich, JM; Rabinowitz, JD; Ryseck, RP; Wang, JZ; Wang, L; Xu, X; Yang, L | 1 |
| Ali, A; Darnell, AM; Joesch-Cohen, L; Kunchok, T; Lewis, CA; Rees, MG; Reilly, MF; Rosenberg, D; Roth, JA; Sullivan, MR; Vander Heiden, MG | 1 |
| Bonabi, E; Mousazadeh, H; Zarghami, N | 1 |
| Aghajanzadeh, M; Danafar, H; Rostamizadeh, K; Sharafi, A; Zamani, M | 1 |
| Chen, J; Gao, X; Hong, Z; Liang, X; Lin, Y; Liu, X; Mi, X; Miao, J; Nie, W; Qian, Z; Ran, M; Wang, B; Yang, T; Yu, T | 1 |
| Aboushoushah, SF; Elbialy, NS; Mohamed, N | 1 |
| Avitabile, C; Conte, C; Dal Poggetto, G; Esposito, D; Laurienzo, P; Moret, F; Quaglia, F; Reddi, E; Romanelli, A; Tiso, N; Ungaro, F | 1 |
| Hou, X; Hu, P; Jiang, X; Li, Y; Wei, X; Yang, D; Yu, X | 1 |
| Chen, X; Li, J; Li, M; Luo, J; Wang, Y; Xin, Q; Xu, X; Yu, P; Zhang, Y | 1 |
| Singh, R; Singh, SK | 1 |
| Gangjee, A; Hou, Z; Matherly, LH | 1 |
| Kipreos, ET; Nawaz, FZ | 1 |
| Korimerla, N; Wahl, DR | 1 |
| Abbasi, M; Asgari, H; Asghari-Jafarabadi, M; Karimi, M; Koruji, M; Miri, SR; Mohammadi, A; Najafi, M; Razavi, SM; Shabani, R; Shams, A | 1 |
| Kaldis, P; Zhao, LN | 1 |
| Chen, H; De Geest, BG; Ge, X; Hao, Y; Li, H; Li, X; Li, Z; Liu, Y; Sun, X; Wang, G; Wang, X; Wu, H; Yang, A; Zhang, J; Zhang, Q; Zhang, X; Zhang, Z; Zhao, H; Zou, J | 1 |
| Jeong, YI; Kim, BH; Kook, MS; Yang, SW | 1 |
| Lei, QY; Li, J; Liu, S; Su, Y; Wang, D; Yin, M; Zhang, F | 1 |
| Li, Q; Lv, X; Tang, C; Yin, C | 1 |
| Azarmi, Y; Babaei, H; Baradaran, B; Ghorbani, M; Hamishehkar, H; Pourradi, NMA; Shanehbandi, D; Shokouhi-Gogani, B | 1 |
| Bi, J; Chen, P; Liu, H; Ning, X; Qu, Y; Shi, F; Tang, L; Xu, Y; Zhang, X | 1 |
| Guo, Z; Jiang, H; Liu, W; Semcheddine, F; Wang, X | 1 |
| Fu, T; Li, Y; Liu, Y; Long, W; Stang, PJ; Tan, W; Yan, Y; Zhang, P; Zhao, Z; Zhou, Z | 1 |
| Dodda, JM; Remiš, T; Rotimi, S; Yeh, YC | 1 |
| Chen, X; Jia, R; Li, G; Li, Z; Wang, Y | 1 |
| Agarwala, S; Bakhshi, S; Bansal, PG; Dhawan, D; Dwivedi, S; Ganguly, S; Gonmei, Z; Srivastava, R; Toteja, GS | 1 |
| Burgucu, N; Huysal, M; Isık, S; Sagir, T; Senel, M; Tabakoglu, O; Zaim, M | 1 |
| Shi, J; Wang, S; Yu, S; Yuan, J; Zhao, S; Zhou, Q | 1 |
| Alhajamee, M; Homayouni Tabrizi, M; Khademi, D; Sadeghzadeh, F; Torshizi, GH; Ziaratnia, AS | 1 |
| Dong, X; Jiang, H; Liu, X; Lu, H; Wang, X; Wang, Y; Xiong, H; Ye, J | 1 |
| Jayasree, RS; Joseph, M; Nair, LV; Pathiripparambath, MSR; Tharayil, H | 1 |
| Bs, U; K, RP; M Joseph, M; R, S; Sen, A; Tt, S | 1 |
| Ding, T; Jiang, Z; Lin, S; Lu, Y; Wang, H; Wang, S; Wei, X; Yang, F; Zhan, C | 1 |
| Fei, X; Li, B; Li, G; Li, J; Liu, H; Liu, M; Liu, W; Yang, G; Yang, Y; Zhang, T; Zhang, X | 1 |
| Ainscow, E; Ang, JE; Banerjee, S; Banerji, U; Basu, B; Biondo, A; Chua, S; Cook, N; de Bono, J; Funingana, IG; Gurel, B; Hall, E; Ingles Garces, A; Jenkins, B; Jones, R; Little, M; Lopez, J; McIntosh, S; Michalarea, V; Minchom, A; Parmar, M; Porter, JC; Prout, T; Raynaud, F; Riisnaes, R; Ruddle, R; Tunariu, N; Turner, A; Zachariou, A | 1 |
| Firouzabadi, K; Karimi, E; Tabrizi, MH | 1 |
| Anvari, B; Lee, CH; Mac, JT; Vankayala, R | 1 |
| Alvestad, S; Bjørk, MH; Christensen, J; Dreier, JW; Gilhus, NE; Gissler, M; Igland, J; Leinonen, MK; Sun, Y; Tomson, T; Vegrim, HM; Zoega, H | 2 |
| Chen, Z; Liu, S; Su, J; Wang, Z; Wu, Y; Xia, H; Yao, Z | 1 |
| Chang, J; Chen, Q; Fang, M; Li, L; Pang, G; Wang, H; Wang, Y; Xing, Y; Xue, X; Zhang, X; Zhang, Y; Zhao, P | 1 |
| Duan, YC; Guan, YY; Xu, YT; Yu, T; Zhang, YZ; Zhao, F; Zhao, Y; Zhou, XL | 1 |
| Gangjee, A; Hou, Z; Matherly, LH; Schneider, M | 1 |
| Afrouz, M; Ahmadian, Z; Alebrahim, MT; Amani, A; Coudret, C; Eftekhari, A; Elias, SG | 1 |
| Adams, GP; Bradbury, MS; Chen, F; Chen, PM; Gardinier, TC; Germano, G; Khor, T; Ma, K; Patel, V; Turker, MZ; Venkatesan, AM; Wiesner, UB; Wu, F | 1 |
| Obeid, R | 1 |
| Blair, SL; Dong, T; Huang, CH; Kummel, AC; Larson, C; Oronsky, B; Phung, AT; Reid, T; Sanchez, AB; Shah, JR; Trogler, WC | 1 |
| Aldhubiab, B; Anwer, MK; Asdaq, SMB; Fattepur, S; Gharsan, MA; Goudanavar, PS; Gowthami, B; Habeebuddin, M; Haroun, M; Islam, MM; Mahalakshmi, SVVNS; Meravanige, G; Naveen, NR; Prasanthi, S; Sreeharsha, N; Telsang, M | 1 |
| Bao, W; Cheng, TD; Fowke, JH; Johnson, KC; Liang, X; Liu, B; Mozhui, K; Saquib, N; Sen, S; Shadyab, AH; Snetselaar, LG; Sun, Y; Wallace, RB | 1 |
| Fogle, HM; Krupenko, NI; Krupenko, SA; McCormac, JP; Molina, S; Rushing, BR; Sharma, J; Sumner, S; You, M | 1 |
| Li, Z; Liang, N; Sun, S; Yan, P; Zhao, W | 1 |
| Chelvam, V; Krishnan, MA; Yadav, K | 1 |
| Abrahamyan, L; Avagyan, M; Demirchyan, A | 1 |
| Assaraf, YG; Levin, M; Stark, M; Ulitsky, I | 1 |
| Barsbay, M; Ghaffarlou, M; Güven, O; İnci, ÖG; Karacaoğlu, E; Karahisar Turan, S; Sütekin, SD | 1 |
| Guo, M; He, X; He, Z; Song, X | 1 |
| Park, HY; Song, BM; Song, S | 1 |
| Mahdieh, A; Nyström, B; Sande, SA; Yeganeh, H | 1 |
| Chang, Q; Lu, F; Peng, Z; Xing, M | 1 |
| Bao, Y; Jin, Y; Li, G; Tang, S; Wang, Z; Wu, X; Yan, R; Zhang, H | 1 |
| Chakraborty, S; Chaudhari, P; Das, S; Kumar, D; Mathur, A; Mirapurkar, S; Mohanty, B; Sakhare, N; Sheela, M | 1 |
| Kellerman, IM; Kruger, M; Ladas, EJ; Lombard, CJ; Rogers, PC; Schoeman, J; Uys, R | 1 |
| Bernardin, F; Bonagas, N; Borhade, S; Chalkiadaki, C; Cookson, V; Eiden, K; Frödin, M; Ghahe, EK; Green, AC; Helleday, T; Henriksson, M; Hodek, O; Homan, E; Jemth, AS; Jiménez-Alonso, JJ; Johansson, AI; Kiweler, N; Lesur, A; Letellier, E; Long, M; Loseva, O; Marttila, P; Meiser, J; Meyers, M; Mortusewicz, O; Moussay, E; Paggetti, J; Ramos, L; Sandberg, L; Slipicevic, A; Sørensen, CS; Vallin, KSA; Viry, E; Wiita, E | 1 |
| Ding, Z; Li, H; Wang, Q; Zhou, Q | 1 |
| Barati Naeeni, N; Ghafaripour, H; Homayouni Tabrizi, M; Karimi, E | 1 |
| Cao, S; Chen, W; Liang, R; Liu, W; Shi, D; Wang, B; Ye, Z; Yu, L | 1 |
| Auvin, S; Devlin, A; Helmstaedter, C; Lagae, L; Marson, A; Meador, KJ; O'Brien, TJ; Park, J; Surges, R; Trinka, E; von Wrede, R; Wiebe, S; Witt, JA | 1 |
| Marnani, MB; Oftadeh, M; Sohrabi, N | 1 |
| Haque, S; Hussain, A; Jain, A; Kumar, A; Saini, AK; Saini, RV; Sak, K; Sethi, G; Sharma, U; Tuli, HS; Uttam, V | 1 |
| Franken, MD; Kampman, E; Kok, DE; Lubberman, FJE; McKay, JA; Tissing, WJE; Zwart, NRK | 1 |
| Chen, L; Chen, Y; Duan, S; Li, Y; Liu, R; Sun, J; Zhang, L | 1 |
| Li, J; Liu, J; Qian, L; Shan, L; Tang, J; Wang, W; Wang, Y | 1 |
| Iqbal, H; Iqbal, Y; Saleem, A; Shabbir, H; Tahir, S; Tehseen Hussain, M | 1 |
| Barsbay, M; Charmi, J; Danafar, H; Ertas, YN; Ghaffarlou, M; Javani, S; Kalantari, Y; Mohammadi, A; Mousazadeh, N; Nosrati, H; Rezaeejam, H; Salehiabar, M | 1 |
| Biocca, S; Camboni, T; Cifola, I; Consolandi, C; Desideri, A; Mangano, E; Severgnini, M; Unida, V | 1 |
| Gaber, M; Ghareeb, D; Hamed, A; Hamed, M; Mohamed, TM; Nofal, MS | 1 |
| Fu, Y; Guo, H; Guo, L; Guo, R; Liu, Y; Luo, Z; Ren, Q; Shi, X; Su, T; Tan, Z; Wang, L; Xing, R; Zhang, C; Zhang, H; Zhang, Y | 1 |
| Alfar, R; Finnell, R; Johnson, A; Low, PS; Napoleon, JV; Shahriar, I; Walchle, C | 1 |
| Abdul Rahman, R; Atil, A; Nawi, AM; Rahman, NAA; Wan Ismail, WR | 1 |
| Chen, X; Mo, R; Shen, S; Xu, X; Zhang, Y; Zhu, Q | 1 |
| Guo, B; Guo, P; Li, Z; Xu, C; Zheng, Z | 1 |
| Krushkal, J; Min, DJ; Vural, S | 1 |
| Öztürk, AA; Şenel, B | 1 |
| Dong, Y; Fan, D; Fu, R; Liang, L; Ma, P; Mi, Y; Yang, J | 1 |
| Fan, F; Guo, Q; Huang, C; Kong, D; Leng, X; Ou-Yang, W; Pan, X; Qin, Y; Sun, H; Wang, H; Zhang, L; Zhang, Z; Zhou, S; Zhu, D | 1 |
| Dai, Z; Gao, X; Locasale, JW; Sanderson, SM | 1 |
| Dong, J; Luo, D; Meng, G; Wei, J; Wu, J; Xia, M; Zheng, M | 1 |
| Bai, YJ; Gong, YK; Li, N; Li, T; Ma, Y; Xing, CM | 1 |
| Malekzadeh, AM; Niknejad, H; Ramazani, A; Rezaei, SJT | 1 |
| Dong, J; He, C; Liu, L; Ma, D; Shao, Y; Wu, H; Xu, F; Yang, R; Yin, J; Zhang, Y | 1 |
| Chen, D; Hu, H; Ji, H; Li, J; Zhao, M | 1 |
| Acharya, S; Chang, JH; Choi, HG; Choi, JY; Jeong, JH; Kim, JH; Kim, JO; Ku, SK; Nguyen, HT; Pham, TT; Phung, CD; Timilshina, M; Yong, CS | 1 |
| Du, Q; Qian, J; Shi, K; Xu, N; Yin, X; Zhao, Z; Zhou, X | 1 |
| Jun, SW; Kang, YH; Kim, CS; Kwon, J; Lee, J; Ly, CD; Manivasagan, P; Mondal, S; Nguyen, VT; Oh, J | 1 |
| Dokukin, M; Feng, H; Laroche, FJF; Palantavida, S; Peerzade, SAMA; Peng, B; Qin, X; Sokolov, I | 1 |
| Fu, S; Yang, J; Yang, T; Zhang, S; Zhi, D | 1 |
| Farran, B; Han, YK; Huh, YS; Kamal, MA; Kasa, P; Montenegro, RC; Nagaraju, GP; Pavitra, E; Rama Raju, GS | 1 |
| Heske, CM; Issaq, SH | 1 |
| Cui, M; Fan, B; Fan, Q; Hu, L; Ma, H; Wang, X; Wei, Q | 1 |
| Cheng, L; Li, J; Liu, C; Liu, Y; Lu, H; Wang, D; Wei, J; Xu, B; Yin, S | 1 |
| Alam, NR; Gholibegloo, E; Haghgoo, S; Khoobi, M; Mesbahi, A; Mortezazadeh, T | 1 |
| Hassan, PA; Pandey, BN; Pandrekar, S; Priyadarsini, KI; Shetake, NG; Verma, G | 1 |
| Boni, FI; Callan, JF; Chorilli, M; de Freitas, LM; de Oliveira, KT; Fontana, CR; McHale, A; Nicholas, D; Oshiro-Junior, JA; Santos, KLM; Sato, MR | 1 |
| Chen, ZX; Cheng, H; Guo, DK; Liu, MD; Wang, SB; Zhang, XZ; Zhong, Z; Zou, MZ | 1 |
| Du, X; Li, L; Li, Y; Wang, S; Wei, S | 1 |
| Daniyal, M; Fan, J; Jian, Y; Liu, B; Peng, C; Sheng, W; Wang, W; Wang, Z; Xiao, C; Xiao, F; Yuhui, Q | 1 |
| Akbari, A; Mohammadzadeh, R; Shahim, P | 1 |
| Khakbaz, F; Mahani, M; Saljoughi, H | 1 |
| Kenar, G; Köksoy, EB; Ürün, Y; Utkan, G | 1 |
| Banerjee, S; Banerji, U; Cojocaru, E; Scaranti, M | 1 |
| Du, R; Qu, Y; Yang, Y; Zhao, M | 1 |
| Cho, HJ; Dimitrova, I; Israilov, S | 1 |
| Kanarek, N; Petrova, B; Sabatini, DM | 1 |
| He, J; Li, L; Liu, J; Ni, P; Song, Y; Zhang, M | 1 |
| Gao, F; Guo, DK; Li, CX; Liu, MD; Wang, SB; Xie, BR; Yu, Y; Zhang, C; Zhang, XZ; Zhong, Z | 1 |
| Du, J; Fan, Y; Fang, S; Feng, W; Shi, C; Tang, Q; Wang, S; Ya, H | 1 |
| Krupenko, SA; Sharma, J | 1 |
| Guéant, JL; Hsu, SB; Namour, F; Oussalah, A; Siblini, Y; Zgheib, R | 1 |
| Chang, CA; Lin, SL | 1 |
| Chang, Y; Guo, Y; Li, S; Liu, P; Liu, T; Ma, X; Meng, L; Yang, L | 1 |
| Chen, Y; Huang, S; Lee, I; Xuan, G; Zhang, M | 1 |
| Jayasree, RS; Jibin, K; Maiti, KK; Prasad, JS; Saranya, G; Shenoy, SJ | 1 |
| Chesori, R; Gniazdowska, E; Halik, PK; Koźmiński, P | 1 |
| Jaune-Pons, E; Vasseur, S | 1 |
| Gupta, MK; Kharkar, PS; Rathod, V; Shetty, S; Soni, G; Yadav, KS | 1 |
| Ge, Z; Han, M; Ji, X; Li, J; Luo, B; Sun, X; Wang, Q; Zhang, W; Zhou, K | 1 |
| Hansen, SI; Holm, J | 1 |
| Klementyeva, O; Larenkov, A; Lunyova, K; Machulkin, A; Maruk, A; Rakhimov, M | 1 |
| Aihara, T; Arima, H; Fukumitsu, N; Hattori, K; Higashi, T; Ishikawa, H; Kumada, H; Matsumoto, Y; Motoyama, K; Nakai, K; Sakurai, H | 1 |
| DeBlasio, M; Iwasaki, A; Jain, PC; Kim, DJ; Klein, J; Lee, S; Medzhitov, R; Tu, SS; Venkataraman, A; Wiesler, EP | 1 |
| Kawashima, H; Morita, T; Nakagawa, F; Nakamura, H | 1 |
| Chen, W; Li, J; Wang, D; Wang, X; Xia, M; Xing, Y; Zhang, H | 1 |
| Das, N; Kadian, S; Manik, G; Roy, P | 1 |
| Jang, JY; Kim, DH; Kim, DW; Kim, HJ; Ko, YJ; Lee, N; Lee, SM; Na, K; Son, SU | 1 |
| Díaz-Rodríguez, E; Pandiella-Alonso, A; Sanz, E | 1 |
| Li, D; Li, Z; Pang, S; Wang, L; Wu, M; Yang, B; Yang, X; Yang, Y; Zhang, J | 1 |
| Chen, S; Chen, Y; Wang, Y; Zhan, J | 1 |
| Darvishi, MH; Hashemzadeh, H; Khaledian, M; Nourbakhsh, MS; Saber, R | 1 |
| Kanarek, N; Petrova, B | 1 |
| Chen, F; Chen, J; Hossain, AMS; Sun, B; Sun, K; Wang, S; Wu, H; Yin, Y; Zhang, Y | 1 |
| Daniels, A; Pillay, NS; Singh, M | 1 |
| Cajaraville, MP; Katsumiti, A; López-Arbeloa, I; Martínez-Martínez, V; Prieto-Montero, R | 1 |
| Liu, C; Ma, X; Qian, J; Sha, D; Yuan, Y; Zhang, S | 1 |
| Emami, J; Hasanzadeh, F; Kazemi, M; Lavasanifar, A; Minaiyan, M; Mirian, M; Mokhtari, M | 1 |
| Dotsenko, O; Shtofel, D | 1 |
| Bernhardt, P; Cohrs, S; Fang, HY; Guzik, P; Müller, C; Schibli, R; Siwowska, K | 1 |
| Bao, J; Cheng, J; Fan, D; Li, J; Shi, Y; Wang, X; Xia, Q; Zu, X | 1 |
| Hu, X; Li, C; Liang, C; Ling, X; Wu, R; Yan, Y; Zou, J | 1 |
| Cai, H; He, Y; Li, F; Liu, Y; Wang, M; Xu, H; Zhao, Y | 1 |
| Agili, F; El-Kalyoubi, S | 1 |
| Chen, Z; He, D; Huang, Z; Li, Y; Liu, H; Qin, L; Wang, P; Wang, W; Wei, C; Zhong, P; Zhou, Y; Zhu, W | 1 |
| Liao, M; Ouyang, L; Wang, Y; Yang, C; Yang, Y; Yuan, Y; Zhang, J | 1 |
| Aizenshtein, E; Besser, E; Lagziel, S; Lee, WD; Mukha, D; Nevo-Dinur, K; Pirona, AC; Raz, S; Sarvin, B; Sarvin, N; Shlomi, T; Stern, A | 1 |
| Kim, I; Kim, J; Song, W; Tran, CH; Varyambath, A; Wang, M; Yu, DG; Zhang, Y | 1 |
| Benedicto, A; Márquez, J; Sanz, E | 1 |
| Hussain, MS; Ilyas, M; Ilyas, S; Iqbal, M; Mathur, S; Schlößer, HA; Ullah, NK; Wennhold, K | 1 |
| Fu, S; Ma, Y; Tan, Y; Zhang, A | 1 |
| Chen, Z; He, D; Huang, Z; Li, Y; Liu, H; Qin, L; Shen, J; Wang, P; Wang, W; Wei, C; Zhu, W | 1 |
| Björklund, M; Caldez, MJ; Kaldis, P; Zhao, LN; Zheng, J | 1 |
| Frühauf, J; Gangjee, A; Hou, Z; Matherly, LH; Ning, C; O'Connor, C; Tong, N; Wallace-Povirk, A | 1 |
| Classen, HG; Eckert, GP; Egert, S; Frank, J; Golombek, J; Kisters, K; Lorkowski, S; Obeid, R; Pettersen, JA; Podszun, MC; Stirban, OA; Venturelli, S; Wallert, M | 1 |
| Gasser, G; Karges, J; Tharaud, M | 1 |
| Cai, M; Li, J; Wang, S; Xu, N; Zhang, H; Zhang, Y; Zhao, Q; Zhou, T | 1 |
| Hu, L; Li, Z; Tian, J; Wang, C; Wei, J; Xiong, C | 1 |
| Amer Ridha, A; Hemati Azandaryani, A; Kashanian, S; Mahdavian, E; Rafipour, R; Zhaleh, H | 1 |
| Chen, H; Jin, J; Kaniskan, HÜ; Liu, J; Liu, Y; Meng, F; Shen, Y; Wei, W | 1 |
| Fei, X; Li, B; Li, G; Li, J; Wang, Z; Zhang, T; Zheng, Y | 1 |
| Chen, J; Du, Q; Huang, J; Lv, F; Tang, X; Zhao, Z | 1 |
| Hai, J; Li, T; Li, X; Lu, S; Mu, X; Sun, S; Wang, B; Zhao, Y | 1 |
| Agarrabeitia, AR; Cajaraville, MP; Katsumiti, A; Martínez-Martínez, V; Ortiz, MJ; Prieto-Castañeda, A; Prieto-Montero, R | 1 |
| Bueverova, E; Dlamini, JC; Ivashkin, V; Kardasheva, S; Kopylov, A; Kurbatova, A; Malsagova, K; Nechaev, V; Sedova, A; Shulpekova, Y | 1 |
| Gao, Y; Guo, F; Hong, W; Ji, X; Li, A; Lou, B; Wang, G; Wang, H; Wu, J; Yang, G; Ying, S; Yu, N | 1 |
| Ding, C; Gong, Y; Guo, X; Yuan, W; Zhang, P; Zhang, Q | 1 |
| Deng, X; Hu, H; Liang, Z; Liu, W; Shao, Z; Song, Q; Wang, B; Wang, S; Xing, X; Yang, W; Zhang, Y; Zhong, B; Zhou, Z; Zhu, J | 1 |
| Do, TTA; Garcia-Celma, MJ; Grijalvo, S; Imae, T; Rodríguez-Abreu, C | 1 |
| Flanders, WD; Hartman, TJ; Hodge, RA; Li, C; McCullough, ML; Mitchell, DC; Patel, AV; Sampson, L; Troeschel, AN; Wang, Y | 1 |
| Aji Alex, MR; Koul, V; Kumar, A; Nehate, C | 1 |
| Chen, H; Fang, Y; Gao, Y; Jiang, M; Li, Z; Lv, T; Yu, T; Zhang, H; Zhang, S; Zhang, Y | 1 |
| Cao, Y; Huang, H; Liu, M; Liu, W; Wang, X; Yang, DP; Zhang, WJ; Zhang, Z; Zhou, G | 1 |
| Chen, X; Chua, MX; Li, Z; Liu, X; Wu, YL | 1 |
| Ge, S; Han, B; Hu, Y; Jiang, J; Li, K; Liu, Y; Wang, Y; Xu, Y; Yin, F; Zhang, L; Zhang, S | 1 |
| Cheng, W; Huang, L; Liang, C; Liu, G; Mei, L; Nie, J; Peng, Y; Wang, T; Xu, L; Zeng, X | 1 |
| Bhattacharjee, P; Giri, AK; Paul, S | 1 |
| Li, JC; Liang, L; Sun, L; Tian, Y; Zhang, HM; Zhu, JX; Zhu, N | 1 |
| Chen, L; Han, G; Huang, L; Kelmar, S; Li, Z; Pendharkar, AI; Wu, W; Yang, J; Yang, Y; Zhang, Y; Zhao, J; Zhao, Y | 1 |
| Li, JL; Li, PH; Shi, JP; Wang, CC; Yu, ZF; Zhang, HW | 1 |
| Cheng, L; Fan, Q; Hao, T; Li, D; Lv, H; Ma, H; Peng, J; Shao, M; Zhao, C; Zong, X | 1 |
| Chen, H; Gao, Y; Li, Z; Lv, T; Xie, X; Zhang, H; Zhang, Y | 1 |
| Akbarzadeh, A; Azadmanesh, K; Chiani, M; Mehrabi, MR; Najmafshar, A; Norouzian, D; Shokrgozar, MA | 1 |
| Joseph, MM; Karunakaran, V; Maiti, KK; Maniganda, S; Ramya, AN; T T, S | 1 |
| Chay, WY; Chia, JWK; Choo, SP; Dent, RA; Koh, KX; Koo, WH; Kwok, LL; Lo, SK; Loh, M; Mok, ZY; Ng, RCH; Soong, RCT; Syn, N; Tan, S; Tham, CK; Toh, HC; Wong, NS; Yap, YS | 1 |
| Alexander, C; Balasso, A; Brazzale, C; Caliceti, P; Jones, AT; Malfanti, A; Mantovani, G; Mastrotto, F; Moody, P; Salmaso, S; Watson, PD | 1 |
| Attaran, N; Beik, J; Ghadiri, H; Ghaznavi, H; Khademi, S; Sarkar, S; Shakeri-Zadeh, A | 1 |
| Hou, R; Li, J; Liu, X; Wang, P; Zhang, J; Zhang, N; Zhang, Z | 1 |
| Behmanesh, M; Charbgoo, F; Nikkhah, M | 1 |
| Chen, F; Di, Y; Gai, X; Jia, L; Li, T; Liu, W; Pan, W; Wang, Y; Yang, X; Zhu, Z | 1 |
| Ding, M; Fu, Q; He, X; Li, J; Li, Y; Shuai, X; Tan, H; Wang, R; Wei, J | 1 |
| Liu, S; Luo, P; Wei, W; Wei, Y; Wei, Z | 1 |
| Han, G; Liu, B; Liu, R; Liu, Z; Yang, L; Zhang, C; Zhang, R; Zhang, Z; Zhao, J; Zhao, T | 1 |
| Dong, W; Gong, J; Guo, C; Hou, J; Liu, E; Liu, S; Shi, Y; Yu, B | 1 |
| Chen, E; Chen, HY; Shen, Y; Sun, Y; Wang, H; Xu, JJ; Yan, R; Ye, D | 1 |
| Ding, G; Du, B; Gu, X; Han, X; Li, D; Wang, E; Wang, J; Wang, Y | 1 |
| Meng, L; Ren, Y; Shao, Y; Wang, D; Yu, D | 1 |
| Ghaznavi, H; Hosseini-Nami, S; Irajirad, R; Kamrava, SK; Maleki, S; Montazerabadi, A; Shakeri-Zadeh, A | 1 |
| Absalom, AR; de Bock, GH; Gernaat, SAM; Huisman, MG; Izaks, GJ; van der Wal-Huisman, H; van Leeuwen, BL; Weerink, LBM | 1 |
| Kim, JD; Park, CW; Park, S; Yang, HM | 1 |
| An, J; Cheng, K; Hou, XL; Li, C; Song, XL; Wang, ZY; Xuan, Y; Yang, XQ; Zhang, RY; Zhao, YD | 1 |
| Donner, J; Fu, C; Herrmann, J; Koehnke, J; Müller, R; Reck, M; Sikandar, A; Wagner-Döbler, I; Zaburannyi, N | 1 |
| Field, MS; Stover, PJ | 1 |
| Chernolovskaya, EL; Gladkikh, DV; Kabilova, TO; Markov, OV; Maslov, MA; Morozova, NG; Shmendel, EV; Zenkova, MA | 1 |
| Aranda-Lara, L; Chairez, I; Ramírez-Nava, GJ; Santos-Cuevas, CL | 1 |
| Furugen, A; Iseki, K; Kobayashi, M; Kurosawa, Y; Narumi, K; Nishimura, A | 1 |
| Chen, L; Huang, L; Li, J; Wang, X; Wang, Y; Xiao, X; Yu, T; Zhang, C; Zhang, Y | 1 |
| Beik, J; Ghadimi-Daresajini, A; Ghaznavi, H; Jafariyan, M; Mahmoudabadi, A; Montazerabadi, A; Shakeri-Zadeh, A; Tarighi, P | 1 |
| Amini, M; Angali, KA; Dorkoosh, FA; Handali, S; Kouchak, M; Moghimipour, E; Ramezani, Z; Rezaei, M | 1 |
| Agrawal, S; Kumar, A; Moulik, NR | 1 |
| Abreu, AS; Cavaco-Paulo, A; Loureiro, A; Nogueira, E; Noro, J; Silva, C; Soares da Costa, D | 1 |
| Chen, XL; Li, YY; Lin, HC; Liu, B; Liu, MC; Lu, JZ; Sun, XY; Yan, SQ; Zhang, LY; Zhao, P | 1 |
| Du, J; Fan, J; Kang, Y; Peng, X; Sun, W; Wang, S | 1 |
| Carron, PM; Crowley, A; Devereux, M; Howe, O; Hunt, M; McCann, M; O'Shea, D | 1 |
| Leblanc, RM; Pardo, J; Peng, Z | 1 |
| Fu, S; Han, L; Lin, J; Liu, C; Lu, X; Yang, C; Zhao, C | 1 |
| Fedorenko, O; Kotova, N; Maichuk, V | 1 |
| Arellano, DL; Chauhan, K; Fournier, PGJ; Hirata, GA; Jain, A; Juárez, P; Sengar, P; Verdugo-Meza, A | 1 |
| Hui, Y; Liu, Y; Middelberg, APJ; Ran, R; Seth, A; Wang, HF; Wibowo, D; Zhao, CX | 1 |
| Kim, YI | 7 |
| Antony, AC; Kusumanchi, P; Stabler, SP; Tang, YS; Xiao, S; Zhang, Y | 1 |
| Cui, R; Gao, X; Ji, G; Liu, Z | 1 |
| Bradley, SJ; Goreham, RV; Holmes, A; Nann, T; Schroeder, KL | 1 |
| AlQhatani, AD; Bashraheel, SS; Dömling, A; Goda, SK; Groves, MR; Rashidi, FB; Shaabani, S | 1 |
| Chen, CY; Chien, YY; Liao, PW; Wang, TY; Wu, WC | 1 |
| Attaran, N; Ay, MR; Ghadiri, H; Khademi, S; Kharrazi, S; Sarkar, S; Shakeri-Zadeh, A | 1 |
| Azevedo, RB; Báo, SN; Coelho, JM; Ganassin, R; Gu, J; Jiang, CS; Longo, JPF; Morais, PC; Mosiniewicz-Szablewska, E; Muehlmann, LA; Py-Daniel, KR; Rodrigues, MC; Souza, LR; Suchocki, P | 1 |
| Bai, Y; Chen, J; Chen, X; Jin, R; Liu, T; Liu, Z; Zhou, Y | 1 |
| Dai, Z; Ma, H; Song, B; Tan, M; Tian, L; Yuan, J; Zheng, X | 1 |
| Bloomfield, A; Dircksen, C; Dorton, R; Kleindl, P; Leamon, CP; Nelson, M; Reddy, JA; Santhapuram, H; Vetzel, M; Vlahov, IR | 1 |
| Meng, F; Ping, Q; Wang, J; Yeo, Y | 1 |
| Liu, H; Shi, L; Tong, G; Wang, D; Wu, J; Xu, L; Yan, D; Yu, C; Zhu, X | 1 |
| Cui, C; Li, J; Sun, Q; Wang, X; Wang, Y | 1 |
| Chen, K; Li, Z; Liu, X; Loh, XJ; Wu, YL | 1 |
| Bai, S; Gao, YE; Hou, M; Kang, Y; Li, B; Ma, X; Shi, X; Xiao, B; Xu, Z; Xue, P | 1 |
| Berry, RJ; Chao, A; Cong, S; Fan, J; Fang, L; Hao, L; Kitahara, CM; Li, Z; Liang, X; Linet, MS; Liu, F; Lu, X; Lv, F; Meng, F; Mu, C; Potischman, N; Sampson, J; Sun, X; Tang, Y; Wan, W; Wang, B; Wang, H; Wang, L; Wang, N; Wang, Y; Yang, R; Yin, P; Zhang, L | 1 |
| Cho, JW; Kim, JH; Kim, JS; Kim, WJ; Nam, YS; Park, K; Seah, GL; Yang, MY; Yu, JH | 1 |
| Jia, C; Ren, T; Sun, H; Tan, X; Yang, Z; Zhang, Y | 1 |
| Day, S; Lammersfeld, C; Paver, S; Pieroth, R | 1 |
| Molitch, ME; Wallia, A | 1 |
| Gao, Z; Sun, B; Wang, M; Wu, H; You, C; Zhang, X | 1 |
| Cao, Y; Chen, Y; Gong, Y; Guo, Y; Li, P; Li, Y; Liu, F; Ran, H; Wang, Z | 1 |
| Bennett, C; Guo, P; Li, Z; Wang, H; Yin, H; Zhang, HG | 1 |
| Gagare, P; Kularatne, SA; Liu, X; Low, PS; Mahalingam, SM; Myers, CH; Norshi, M; Singhal, S | 1 |
| de Groot, LCPGM; Kiefte-de Jong, JC; Lemmens, V; Oliai Araghi, S; Stricker, BH; Swart, KMA; Uitterlinden, AG; van der Velde, N; van Dijk, SC; van Laarhoven, HW; van Schoor, NM | 1 |
| Choi, E; Han, J; Kim, CS; Min, HK; Nguyen, VD; Park, JO | 1 |
| Derakhshanfar, S; Dong, S; He, W; Huang, Q; Liao, W; Liu, Y; Luo, GX; Rao, J; Shi, M; Xing, M; Zhang, S; Zhong, W | 1 |
| Hu, Y; Shi, X; Song, T; Sun, R; Wang, R; Yan, Y; Yin, S | 1 |
| Ge, XJ; Gong, YC; Li, YP; Li, ZL; Xiong, XY | 1 |
| Chen, J; Chen, X; Chen, Y; Tan, X; Wang, J; Yang, Z | 1 |
| Ahn, GO; Bok, S; Jeong, S; Jung, Y; Kim, M; Kim, S; Kim, SY; Kim, YE; Lee, S; Ryu, YM; Song, J | 1 |
| Akhtar, N; Farook, AS; Girigoswami, A; Girigoswami, K; Haribabu, V; Sharmiladevi, P | 1 |
| Jungert, A; Neuhäuser-Berthold, M | 1 |
| Gregersen, H; Luo, L; Maruf, A; Nurhidayah, D; Wang, GX; Wang, Y; Wu, W; Zhong, Y | 1 |
| Dai, Y; Gai, S; He, F; Li, W; Liu, S; Suh, YD; Yang, G; Yang, P; Zhong, C | 1 |
| Feng, S; Gao, XD; Nakanishi, H; Xu, S; Zhang, H; Zhi, C | 1 |
| Bi, Y; Hao, F; Lee, RJ; Meng, F; Sun, Y; Teng, L; Teng, S; Yao, Y; Zhang, H; Zhao, X; Zhao, Y; Zheng, X | 1 |
| Chen, L; Chen, Z; Liu, J; Song, H; Wang, W; Yan, C; Yang, N; Zhao, J; Zhao, Y | 1 |
| Chen, Q; Hong, Z; Li, G; Li, S; Liu, Q; Wang, J | 1 |
| Chen, M; Guo, Y; Lei, B; Ma, PX; Niu, W; Wang, M; Xue, Y | 1 |
| Bansal, S; Barnwal, RP; Chatterjee, M; Kaur, IP; Kumar, R; Kumari, U; Singh, G; Singh, J; Singh, S | 1 |
| Aresh, W; Chen, CW; Lai, PS; Nieh, MP; Tahmasbi Rad, A; Xia, Y | 1 |
| Krupenko, NI; Krupenko, SA | 1 |
| Arora, R; Bansal, AK; Bhattacharya, R; Hasan, T; Sharma, GS; Singh, LR | 1 |
| Dai, Y; Fan, Q; Li, M; Ma, W; Shen, Q; Su, J; Sun, P; Wang, B; Wang, Q; Wu, K | 1 |
| Bizzoni, C; Figini, M; Frigerio, B; Jansen, G; Leamon, CP; Low, PS; Matherly, LH; Peters, GJ | 1 |
| Cai, Y; Chen, J; Ding, H; Lu, T; Nie, G; Wang, X; Wen, W | 1 |
| Amanlou, M; Bigdeli, B; Dehghani, S; Goliaei, B; Hosseini, M; Khoobi, M; Lotfabadi, A; Naeimi, H; Nejadshafiee, V; Nezamtaheri, MS; Sadighi, A; Sharifzadeh, M | 1 |
| Dou, YK; He, XW; Li, WY; Li, YH; Shang, Y; Zhang, YK | 1 |
| Barone, G; Collina, S; La Franca, M; Raimondi, MV; Randazzo, O; Rossi, D; Vignoni, E | 1 |
| Cheng, D; Lin, Y; Qian, X; Shi, H; Tang, Y; Xu, Y; Zhang, J; Zhu, W | 1 |
| Chen, HY; Hu, SW; Li, XL; Wang, J; Xu, JJ; Zhang, TT | 1 |
| Byeon, JH; Hwang, J; Kim, JO; Ku, SK; Poudel, BK | 1 |
| Bolze, F; Heitz, V; Jenni, S; Sour, A; Ventura, B | 1 |
| Lee, DJ; Wagner, E | 1 |
| Abdi Goushbolagh, N; Amini, B; Darkhor, P; Farhood, B; Mohammadnejad, J; Narmani, A; Refahi, S; Rezvani, M | 1 |
| Chu, H; Leamon, CP; Lee, YG; Low, PS; Lu, Y; Putt, KS; Srinivasarao, M | 1 |
| Berindan-Neagoe, I; Braicu, C; Ciocan, C; Cojocneanu, R; Coza, O; Gulei, D; Irimie, AI; Magdo, L; Olariu, A; Pasca, S | 1 |
| Mazzaglia, A; Monsù Scolaro, L; Piperno, A; Rapozzi, V; Scala, A; Trapani, M; Triolo, C; Xodo, LE; Zagami, R | 1 |
| Hong, T; Song, X; Wang, Z; Yue, Z; Zhang, S | 1 |
| Choi, JY; Chung, H; Im, HJ; Jeong, JM; Kang, KW; Kim, EE; Kim, JY; Kim, KW; Kim, WH; Kim, YJ; Lee, DS; Lee, YS; Lodhi, NA; Oh, C; Park, JY; Seok, SH; Song, MG | 1 |
| Guo, L; Liu, C; Liu, J; Ma, H; Song, B; Yuan, J; Zhang, R; Zhang, W | 1 |
| Fang, Z; Jiang, B; Li, X; Mei, T; Sun, N; Wang, D; Wong, KY; Yao, G; Zhou, X | 1 |
| Chu, H; Felten, AE; Leamon, CP; Lu, YJ; Nelson, M; Parker, N; Reddy, JA; Shillingford, JM; Vaughn, JF; Vlahov, IR; Wang, EZ; Westrick, E; Xu, LC | 1 |
| García de Quinto, H; Hernando-Requejo, O; Rubio Rodríguez, MªC | 1 |
| Gao, W; Liu, F; Meng, TT; Qi, XR; Xiang, B | 1 |
| Jain, NK; Jain, V; Mehra, NK; Singh, R | 1 |
| Chen, Q; Liu, H; Shen, M; Shi, X; Wen, S; Xu, Y; Zhang, G; Zhao, J; Zheng, L | 1 |
| Akhavan-Niaki, H; Samadani, AA | 1 |
| Dong, DW; Gao, W; Li, JQ; Qi, XR; Xiang, B; Yang, ZZ | 1 |
| Lee, KY; Lim, YC; Seow, E; Zhang, Y | 1 |
| Choi, JW; Kang, E; Kim, SW; Kwon, OJ; Yun, CO | 1 |
| Che, X; Liu, P; Liu, Y; Lu, L; Wu, J; Xie, X; Xu, X; Yu, H; Yu, J | 1 |
| Cai, H; Chen, Q; Li, K; Liu, H; Peng, C; Shen, M; Shi, X; Wen, S; Zhang, G | 1 |
| Li, H; Liu, J; Liu, Y; Miao, Y; Wang, E; Wang, J; Wang, T; Xu, S | 1 |
| Chen, H; Huo, X; Li, T; Liu, J; Wang, B; Wang, R; Yang, Z; Zhang, H; Zhang, W | 1 |
| Lu, Q; Meng, L; Niu, L | 1 |
| Bag, N; Chauhan, RP; Kaul, A; Kumar, H; Mathur, R; Mishra, AK; Patra, M; Singh, G; Singh, S | 1 |
| Chelvam, V; Kelderhouse, LE; Kularatne, SA; Low, PS; Mahalingam, S; Poh, S; Wayua, C | 1 |
| Li, W; Qu, X; Ren, J; Wang, J; Wu, L | 1 |
| Allen, TC | 1 |
| Ametamey, SM; Fischer, CR; Groehn, V; Müller, C; Reber, J; Schibli, R | 1 |
| Ahmed, E; Hammond, PT; Morton, SW; Swager, TM | 1 |
| Chang, YJ; Chiu, CC; Ho, JA; Hsu, SL; Lu, HY; Teng, IT; Wang, LS; Wu, LC; Yang, CH; Yang, CM | 1 |
| Carazo, A; Delgado, AV; Gómez-Sotomayor, R; Munoz-Gamez, JA; Rudzka, K; Ruiz-Extremera, A; Salmerón, J; Viota, JL | 1 |
| Banaszak Holl, MM; Choi, SK; Huang, B; Kotlyar, A; Orr, BG; Silpe, JE; Sumit, M; Thomas, TP; van Dongen, MA | 1 |
| Han, JH; He, Y; Hong, KS; Jeon, HM; Kang, C; Kim, JS; Lee, H; Lee, JH; Park, N; Yang, Z | 1 |
| Liu, ZJ; Song, XX; Tang, Q | 1 |
| Chaudhary, D; Guo, J; Li, D; Wang, CC; Yu, M; Zhang, YT | 1 |
| Deng, J; Mao, L; Mu, X; Qi, L; Qiao, J | 1 |
| Kelderhouse, LE; Low, PS; Sturgis, JE; Vlashi, E | 1 |
| Carron, JD; Hakenjos, J; Henne, KL; Henne, WA; Kularatne, SA | 1 |
| Ganaie, BA; Nazki, FH; Sameer, AS | 1 |
| Bertino, JR; Boros, LG; Chan, LL; DiPaola, RS; Dolfi, SC; Dvorzhinski, D; Gounder, M; Hirshfield, KM; Lin, H; Markert, EK; Oltvai, ZN; Qiu, J; Tedeschi, PM; Vazquez, A | 1 |
| Abbonante, V; Achilli, C; Balduini, A; Balduini, C; Canobbio, I; Cansolino, L; Ciana, A; Fagnoni, M; Grandi, S; Guidetti, GF; Malara, A; Merli, D; Minetti, G; Mustarelli, P; Tomasi, C | 1 |
| Chen, H; Dai, S; Gu, Y; Jin, J; Li, B; Li, J; Ma, Y; Qiu, J | 1 |
| Li, J; Yin, H; Zhao, F | 1 |
| Patil, SP | 1 |
| Chen, Z; Cui, W; Liu, L; Song, H; Su, C; Zhao, L; Zhu, B | 1 |
| Hou, Z; Matherly, LH; Wilson, MR | 1 |
| Abbate, V; Al-Jamal, KT; Al-Jamal, WT; Awad, GA; Bals, S; Bourgognon, M; El-Gogary, RI; Kafa, H; Kamel, AO; Klippstein, R; Leroux, F; Mortada, ND; Naeem, M; Rubio, N; Van Tendeloo, G; Wang, JT | 1 |
| Bloomfield, A; Dorton, R; Guan, J; Leamon, CP; Nelson, M; Reddy, JA; Vetzel, M | 1 |
| Asplund, A; Huang, J; Jain, M; Kampf, C; Madhusudhan, N; Mootha, VK; Nilsson, R; Sheppard, NG; Strittmatter, L | 1 |
| Chen, J; Cui, L; Jin, CS; Wang, F; Zheng, G | 1 |
| Briguglio, I; Carta, A; Corona, P; Costi, MP; Ferrari, S; Luciani, R; Paglietti, G; Piras, S | 1 |
| Balasubramanian, S; Girija, AR; Iwai, S; Kizhikkilot, V; Maekawa, T; Nagaoka, Y; Nair, SD; Suzuki, M; Yoshida, Y | 1 |
| Axup, J; Biroc, SL; Deshmukh, V; Ensari, S; Gymnopoulos, M; Javahishvili, T; Kim, C; Knudsen, N; Kularatne, SA; Manibusan, A; Pinkstaff, J; Schultz, PG; Shimazu, M; Smider, V; Srinagesh, S; Sun, Y; Xia, J; Zou, N | 1 |
| Cho, HJ; Dong, S; Lee, YW; Roman, M | 1 |
| Elsinga, P; Fanti, S; Maurer, AH; Nguyen, B; Oyen, WJ; Weber, WA | 1 |
| Du, C; Li, H; Liang, B; Shuai, X; Sun, Q; Yang, Q; Zhang, Z; Zhong, J | 1 |
| Gao, J; Liu, R; Liu, Y; Ma, R; Shi, J; Wang, L; Zhang, J; Zhang, Z | 1 |
| Bizzarri, R; Caltagirone, C; Falchi, AM; Lampis, S; Lippolis, V; Meli, V; Monduzzi, M; Murgia, S; Prodi, L; Schmidt, J; Sgarzi, M; Talmon, Y | 1 |
| Bugno, J; Burdette, JE; Hong, S; Lantvit, D; Sunoqrot, S | 1 |
| Chen, Z; Feng, Y; Hong, Z; Huang, W; Kong, X; Li, M; Li, Y; Tian, R; Wang, J; Wu, W; Yu, M | 1 |
| Kwag, DS; Lee, ES; Oh, KT | 1 |
| Ikoma, T; Tagaya, M; Tanaka, J; Xu, Z | 1 |
| Shen, M; Shi, X; Tang, Y; Wen, S; Zhang, G; Zheng, L; Zhu, J | 1 |
| Gu, Z; Hu, Z; Ruan, L; Yang, Y; Yin, W; Zhang, X; Zhao, Y; Zheng, X; Zhou, L | 1 |
| An, L; Cao, Q; Deng, Y; Liang, G; Yuan, Y; Zhang, J | 1 |
| Cao, M; Chen, H; Guo, J; Liu, J; Shi, L; Sun, L; Wei, Z; Wen, T | 1 |
| Chen, H; Pang, X; Xi, Y; Yang, C; Zhai, G; Zhao, J | 1 |
| Guo, X; Qu, Q; Shi, C; Tang, Z; Wang, Y; Zhou, S | 1 |
| Ding, J; Li, X; Wang, J; Wang, X; Wei, K; Weng, J | 1 |
| Asande, M; Candeloro, P; Cojoc, G; Coluccio, ML; De Vitis, S; Di Fabrizio, E; Limongi, T; Malara, N; Mollace, V; Perozziello, G; Prati, U; Raimondo, R; Raso, C; Renne, M; Roveda, L; Trunzo, V | 1 |
| de la Garza, AL; Haslberger, AG; Lovrecic, L; Martinez, AJ; Migliore, L; Milagro, FI; Peterlin, B; Remely, M | 1 |
| Choi, Y; Kim, J; Tung, CH | 1 |
| Ao, L; Gao, D; Huang, L; Liu, P; Su, W; Wang, B; Wu, C; Yue, C | 1 |
| Gilreath, JA; Rodgers, GM | 1 |
| Mirza, AZ | 1 |
| Correia, IJ; Costa, EC; Gaspar, VM; Pichon, C; Queiroz, JA; Sousa, F | 1 |
| He, D; Huang, F; Jiang, H; Li, M; Liu, Q; Lu, Z; Ma, L; Na, N; Niu, C; Ouyang, J; Xu, S | 1 |
| Dai, C; Wang, Y; Yan, XP | 1 |
| Priami, C; Thanh, VH; Zunino, R | 1 |
| Duan, X; Evans, DG; Li, C; Liang, R; Liu, W; Ma, L; Wei, M; Yan, D; Zhang, L | 1 |
| Ahlers, CM; Alland, L; Clemens, PL; Cohen, LJ; de Jonge, M; Goss, GD; Hartmann, LC; Jonker, DJ; Konner, J; Marshall, J; Martin, L; Peethambaram, PP; Plummer, ER; Teslenko, V | 1 |
| Gupta, ED; Liew, SC | 1 |
| Li, J; Man, H; Shen, J; Shi, J; Sun, X; Yu, Y; Zhang, H | 1 |
| Ding, C; Tian, Y | 1 |
| Cao, W; Chen, Y; Hsing, IM; Huang, L; Pidhatika, B; Shu, Y; Tian, Q; Wen, W; Wu, H; Xiong, B; Zhou, J | 1 |
| Choi, SK; Wong, PT | 1 |
| Chu, PK; Li, H; Li, P; Liao, R; Liu, F; Shang, Y; Shrestha, L; Xu, H; Xu, Z; Yan, K | 1 |
| Gong, A; Liang, H; Lu, G; Luo, S; Ma, X; Pan, Y; Ren, W; Wu, A; Zeng, L; Zhang, L | 1 |
| Athanassiou, A; Ciofani, G; de Sousa, EM; Ferreira, TH; Liakos, I; Marino, A; Mattoli, V; Mazzolai, B; Nitti, S; Rocca, A | 1 |
| Consoli, GM; Fragassi, G; Geraci, C; Granata, G; Grossi, M; Sallese, M | 1 |
| Qiu, L; Yan, L | 1 |
| Bin, J; Chen, Y; Deng, YL; Jiang, G; Le, DE; Li, M; Liao, Y; Lin, ZT; Liu, Y; Wang, H; Xiao, Y | 1 |
| Lan, M; Tao, L; Yuan, H; Zhang, D; Zhao, H | 1 |
| Huang, L; Liu, D; Liu, G; Liu, Y; Mei, L; Tao, W; Yu, Q; Zeng, X; Zhang, J; Zhu, X | 1 |
| Kouchakzadeh, H; Safavi, MS; Shojaosadati, SA | 1 |
| Kim, J; Kim, KS; Na, K; Park, SJ | 1 |
| Atkinson, C; Bhattacharya, S; Campbell, D; Davey Smith, G; Leary, S; Ness, A; Penfold, C; Taylor, CM | 1 |
| Farhadyar, N; Karamipour, Sh; Sadjadi, MS | 1 |
| Chen, RC; Chen, WT; Kang, ST; Lin, JL; Wang, CH; Yeh, CK | 1 |
| Cal, PM; Cordeiro, C; Frade, RF; Gois, PM | 1 |
| Jang, C; Lee, JH; Sahu, A; Tae, G | 1 |
| Cai, L; He, D; He, X; Li, L; Qing, Z; Wang, K; Wen, L; Xiong, J; Yang, X; Zou, Z | 1 |
| Li, W; Yiu, TT | 1 |
| Burdge, GC; Lillycrop, KA; Price, RJ | 1 |
| Choi, SJ; Kim, HW; Lee, SY; Seo, SJ | 1 |
| Chelvam, V; Low, PS; Poh, S | 1 |
| Jain, NK; Mehra, NK | 1 |
| Prieto, L; Sonnay, M; Zelder, F | 1 |
| Bu, X; Chen, Y; Han, Y; Jiang, Y; Li, S; Li, Z; Lin, Q; Su, C; Xu, H; Yang, X | 1 |
| Chen, F; Liu, W; Peng, Y; Tang, H; Wang, B; Wang, Z; Zhang, H; Zuo, W | 1 |
| Bahrami, B; Bakhshaei, P; Ghalamfarsa, G; Hojjat-Farsangi, M; Jadidi-Niaragh, F; Mohammadnia-Afrouzi, M; Sadreddini, S; Yazdani, Y; Yousefi, M | 1 |
| Ding, H; Ma, YY; Xiong, HM | 1 |
| Bernhardt, P; Brandt, S; Groehn, V; Haller, S; Müller, C; Reber, J; Schibli, R | 1 |
| Huang, H; Li, Y; Nan, S; Sun, Y; Wang, J; Zhang, L | 1 |
| Baros, F; Frochot, C; Jetpisbayeva, G; Myrzakhmetov, B; Stallivieri, A | 1 |
| Lai, WF; Lin, MC | 1 |
| Hicks, BM; Jednorski, AH; Kerezsi, CR; Patil, SP | 1 |
| Li, Z; Ma, X; Shen, Z; Tan, M; Wu, A; Wu, H; Yang, S | 1 |
| Guo, F; Li, N; Tan, F; Wang, J; Yu, M | 1 |
| Boukherroub, R; He, L; Li, M; Mandler, D; Szunerits, S; Wang, Q | 1 |
| Dana, H; Douna, V; Kosmidis, H; Kossiva, L; Maritsi, DN; Vartzelis, G | 1 |
| Cao, W; Gao, G; Gu, Y; Li, S; Liu, M; Shan, L; Wu, C; Xu, L; Zhao, L | 1 |
| Lan, M; Tao, L; Yu, R; Yuan, H; Zhao, H | 1 |
| Finglas, P; Huybrechts, I; Knaze, V; Nicolas, G; Roe, M; Slimani, N; Vignat, J; Witthöft, CM | 1 |
| Liu, Z; Tang, R; Wang, S; Wang, Y; Zhao, R | 1 |
| Bjørge, T; Fomina, T; Melbye, M; Mortensen, JH; Tretli, S; Vollset, SE; Øyen, N | 2 |
| Hu, Y; Qin, F; Shou, D; Xu, B; Xu, J; Xu, Y | 1 |
| Chiang, EP; Ko, HA; Lin, YJ; Tang, FY; Wang, YC; Wu, MT | 1 |
| Liao, H; Lv, Y; Ma, X; Song, X; Tan, M; Wang, H; Wu, H | 1 |
| Chang, J; Hao, Y; Hu, Y; Niu, M; Wang, L; Zhang, B; Zhang, H; Zhang, Y; Zhang, Z; Zhao, H; Zheng, C | 1 |
| Bahadur, D; Bhargava, P; Gupta, J; Mohapatra, J | 1 |
| Iyer, K; Jain, RR; Lohade, AA; Menon, MD; Pawar, Y; Rajan, MG; Roy, SK; Shimpi, HH | 1 |
| Assaraf, YG; Costi, MP; D'Arca, D; Ferrari, S; Marraccini, C; Marverti, G; Ponterini, G; Severi, L; Taddia, L | 1 |
| Firuzi, O; Hamidi, M; Miri, R; Mohammadi-Samani, S; Rostamizadeh, K; Sadighian, S; Zarrin, A | 1 |
| Afriyie-Gyawu, E; Ampofo-Yeboah, A; Ifebi, E; Kyte, B; Shrestha, S; Zhang, J | 1 |
| Amitay, Y; Gabizon, A; Ohana, P; Patil, Y; Shmeeda, H | 1 |
| Guo, J; Li, Y; Sun, L; Wan, J; Wang, C; Zhang, Z | 1 |
| Peng, C; Shen, M; Shi, X; Tang, Y; Yang, J; Zhang, G; Zhou, B; Zhu, J; Zhu, X | 1 |
| Klein, PJ; Leamon, CP; Nelson, M; Pugh, M; Rao, SI; Reddy, JA | 1 |
| Wen, L; Xing, D; Yang, S; Zhong, J | 1 |
| Liu, W; Pan, J; Wan, D; Wang, H; Wang, L | 1 |
| Hu, J; Juan, W; Sahyoun, NR | 1 |
| Butchar, JP; Byrd, JC; Caligiuri, MA; Carson, WE; Davis, M; Elavazhagan, S; Jaime-Ramirez, AC; Jarjoura, D; Jones, NB; Karpa, V; Kondadasula, S; La Perle, KM; Lee, RJ; Li, H; Li, J; Lu, Y; Luedke, E; Mani, A; Mao, H; McMichael, E; Mundy-Bosse, BL; Pan, X; Phelps, M; Poi, M; Roda, J; Schmitt, AC; Skinner, CC; Tridandapani, S; Zhang, X | 1 |
| Cheng, D; Fan, C; Huang, Q; Jiang, D; Li, J; Li, Q; Lv, M; Shi, J; Sun, Y; Tian, T; Wang, L; Xia, J; Zhang, L; Zhu, B | 1 |
| Feng, Y; Huang, L; Ju, H; Luo, Y; Tian, J; Yu, BY | 1 |
| Chen, HP; Chen, MH; Liu, TY; Tung, FI | 1 |
| Cai, L; Gong, P; Liu, P; Ma, Y; Sheng, N; Yi, H | 1 |
| Guo, F; Lei, M; Li, N; Ma, M; Pang, X; Tan, F; Tan, X; Wang, J; Yu, M | 1 |
| Ghosh, S; Joseph, MM; Maiti, KK; Mohapatra, S; Nair, JB; Safeera, M; Sreelekha, TT | 1 |
| Shao, C; Tang, R; Wang, B; Wang, X; Xiao, Y; Yang, X; Zhao, R | 1 |
| Gu, J; Hou, FF; Huo, Y; Jiang, H; Jiang, X; Lei, Y; Li, Y; Qin, X; Shen, L; Wang, B; Wang, X; Zhang, R | 1 |
| Eggers, PK; Lim, LY; Mo, J; Raston, CL; Yuan, ZX | 1 |
| Jia, X; Liu, L; Liu, P; Tian, K; Zeng, J; Zhao, X; Zhou, T | 1 |
| Chen, Q; González Trotter, D; Haley, H; Lin, SA; Low, PS; McQuade, P; Meng, X; Miller, P; Rubins, D; Zeng, Z | 1 |
| Li, W; Liu, L; Liu, Q; Zhang, P | 1 |
| Chu, Y; Li, J; Li, X; Mu, H; Shi, Y; Sun, K; Wang, A; Wang, M; Wu, Z; Zhang, X | 1 |
| Hsiao, M; Huang, TH; Huang, WC; Huang, YJ; Huynh, TT; Lin, CM; Liu, TZ; Su, YH; Sue, YK; Wu, AT | 1 |
| Ghaznavi, H; Hosseini-Nami, S; Kamrava, SK; Samadian, H; Shakeri-Zadeh, A | 1 |
| Boyles, AL; Coates, PM; Thayer, KA; Yetley, EA | 1 |
| Cun, X; Gao, H; He, Q; Hu, C; Hu, G; Kuang, Q; Ruan, S; Shi, K; Wang, Y; Xiao, W | 1 |
| Dong, B; Peng, Y; Wang, Z | 1 |
| Ding, L; Hu, Y; Li, J; Luo, Y; Shen, M; Shi, X; Wang, R; Wang, S; Wang, X | 1 |
| Du, J; Gao, M; Guo, Z; Liu, T; Shi, C; Song, M; Su, X; Xu, D; You, L; Zhang, P; Zhang, X; Zhuang, R | 1 |
| Chen, B; Cheng, Y; Li, H; Liu, Y | 1 |
| Carter, T; Chester, K; Mulholland, P | 1 |
| Guo, L; Lin, Z; Ni, J; Qiu, B; Wang, Q; Yang, HH; Yang, W; Zhang, Y; Zhao, M | 1 |
| Afzal, M; AlAjmi, MF; Bano, S; Mazhar, K; Munir, S; Nazir, S | 1 |
| Assaraf, YG; Raz, S; Stark, M | 1 |
| Danenberg, PV; Gustavsson, B; Johnston, P; Lindberg, P; Moser, R; Odin, E; Peters, GJ; Petrelli, N | 1 |
| Middelberg, APJ; Ran, R; Zhao, CX | 1 |
| Gao, D; Li, Y; Liu, Q; Luo, D; Wang, M; Yang, J; Zhang, Z | 1 |
| Afzal, M; Alamgir, K; Bano, S; Nazir, S; Waraich, MM | 1 |
| Baek, SW; Choi, SW; Lee, GJ; Rhee, CK; Ryu, TK | 1 |
| Chu, CC; He, M; Liu, J; Ro, L | 1 |
| Aboagye, EO; Adams, JE; Aerts, HJ; Barrington, SF; Beer, AJ; Boellaard, R; Bohndiek, SE; Brady, M; Brindle, KM; Brown, G; Buckley, DL; Chenevert, TL; Clarke, LP; Collette, S; Cook, GJ; deSouza, NM; Dickson, JC; Dive, C; Evelhoch, JL; Faivre-Finn, C; Gallagher, FA; Gilbert, FJ; Gillies, RJ; Goh, V; Griffiths, JR; Groves, AM; Halligan, S; Harris, AL; Hawkes, DJ; Hoekstra, OS; Huang, EP; Hutton, BF; Jackson, A; Jackson, EF; Jayson, GC; Jones, A; Koh, DM; Lacombe, D; Lambin, P; Lassau, N; Leach, MO; Lee, TY; Leen, EL; Lewis, JS; Liu, Y; Lythgoe, MF; Manoharan, P; Maxwell, RJ; McShane, LM; Miles, KA; Morgan, B; Morris, S; Ng, T; O'Connor, JP; Padhani, AR; Parker, GJ; Partridge, M; Pathak, AP; Peet, AC; Punwani, S; Reynolds, AR; Robinson, SP; Shankar, LK; Sharma, RA; Soloviev, D; Stroobants, S; Sullivan, DC; Taylor, SA; Tofts, PS; Tozer, GM; van Herk, M; Walker-Samuel, S; Wason, J; Waterton, JC; Williams, KJ; Workman, P; Yankeelov, TE | 1 |
| Caudill, MA; Costa, M; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Malysheva, O; Parvez, F; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Acherar, S; Arnoux, P; Colombeau, L; Frochot, C; Jetpisbayeva, G; Moussaron, A; Myrzakhmetov, B; Stallivieri, A; Vanderesse, R | 1 |
| Huang, Y; Mao, K; Zhang, B; Zhao, Y | 1 |
| Chen, J; He, Z; Huang, J; Huang, X; Jiang, H; Ma, J; Wu, J; Wu, Y; Xia, J; Zhang, X | 1 |
| Yan, XP; Yang, CX; Zhao, HX | 1 |
| Chen, X; Loh, XJ; Owh, C; Qiu, YK; Wu, YL | 1 |
| Cipolleschi, MG; Dello Sbarba, P; Marzi, I; Olivotto, M; Rovida, E | 1 |
| Mashhadi Malekzadeh, A; Niknejad, H; Ramazani, A; Tabatabaei Rezaei, SJ | 1 |
| Adamo, G; Al-Sheikhly, M; Bondì, ML; Bulone, D; Campora, S; Dispenza, C; Ghersi, G; Grimaldi, N; Sabatino, MA | 1 |
| Garg, S; He, W; Li, Z; Liu, J; Luan, Y; Ma, N; Song, Y | 1 |
| Bandara, NA; Bates, CD; Hoylman, EK; Low, PS; Lu, Y | 1 |
| Chen, G; Pang, DW; Ren, JG; Sa, GL; Wu, M; Xia, HF; Yu, ZL; Zhang, W; Zhao, YF; Zhu, JY | 1 |
| Bu, LL; Cai, B; Guo, SS; Huang, Q; Li, A; Liu, W; Meng, QF; Rao, L; Sun, ZJ; Wang, TH; Zhang, WF; Zhao, XZ | 1 |
| Gao, YE; Hou, M; Kang, Y; Liu, S; Shi, X; Xu, Z; Xue, P | 1 |
| Gao, G; Jia, F; Lin, Q; Piao, M; Shen, X; Su, C; Wang, Y; Yang, J; Yang, X; Zhang, L | 1 |
| Gupta, A; Kaur, CD; Saraf, S | 1 |
| Dervisevic, M; Isik, S; Sagir, T; Şenel, M | 1 |
| Guo, Y; Li, S; Wang, Y; Zhang, S | 1 |
| Bai, Q; Xu, L; Yang, H; Zhang, X | 1 |
| Licata, NA; Tkachenko, AV | 1 |
| Kile, ML; Ronnenberg, AG | 1 |
| Low, PS; Sega, EI | 1 |
| Barberi-Heyob, M; Bastogne, T; Didelon, J; Frochot, C; Gravier, J; Guillemin, F; Schmitt, F; Schneider, R | 1 |
| Boynton, A; Gregory, JF; James, SJ; Liu, AY; Neuhouser, M; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM | 1 |
| Chen, S; Cheng, SX; Gu, ZW; Zhang, XZ; Zhuo, RX | 1 |
| Davis, CD; Ross, SA | 1 |
| Nijhout, HF; Reed, MC; Ulrich, CM | 1 |
| Hattori, Y; Hayama, A; Kawano, K; Maitani, Y; Yamamoto, T; Yokoyama, M | 1 |
| Ulrich, CM | 2 |
| Bloomfield, A; Dorton, R; Emsweller, K; Leamon, CP; Parker, N; Reddy, JA; Westrick, E | 1 |
| Assaraf, YG; Ifergan, I | 1 |
| Chen, Y; Ko, S; Liu, H; Mao, C | 1 |
| Halsted, CH | 1 |
| Aghajanian, CA; Fury, M; Gerst, S; Goss, TL; Hensley, ML; Konner, J; Larkin, J; Orlando, M; Sabbatini, P; Tai, DF | 1 |
| BROCKMAN, GF; SIMPSON, GL | 1 |
| ROCCHIETTA, S | 1 |
| BASS, AD; FREEMAN, ML | 1 |
| Hamid, A; Kaur, J; Wani, NA | 2 |
| Asthana, A; Gupta, U; Jain, NK; Singh, P | 1 |
| Hattori, Y; Kawano, K; Maitani, Y; Ohguchi, Y | 1 |
| Albert, CM; Buring, JE; Cook, NR; Gaziano, JM; Manson, JE; Zhang, SM | 1 |
| Leamon, CP | 1 |
| Choi, SW; Mason, JB; Sauer, J | 1 |
| Feng, SS; Pan, J | 1 |
| Jain, NK; Kumar, PV; Tekade, RK | 1 |
| Albanes, D | 1 |
| Feng, L; Gu, B; Han, X; Liu, J; Liu, M; Liu, Y; Lu, W; Xie, C; Zhan, C | 1 |
| de Jong, M; Mindt, TL; Müller, C; Schibli, R | 1 |
| Albala, C; Barrera, G; Bunout, D; de la Maza, MP; Hirsch, S; Leiva, L; Sanchez, H | 1 |
| Eriksson, JE; Lindén, M; Meinander, A; Niemi, R; Peuhu, E; Rosenholm, JM; Sahlgren, C | 1 |
| Beliën, JA; Calhau, C; Giovannetti, E; Jansen, G; Kathmann, I; Lemos, C; Peters, GJ; Scheffer, GL | 1 |
| Lee, LJ; Lee, RJ; Yu, B; Zhao, X | 1 |
| Vastag, B | 2 |
| Eschbach, K; Goodwin, JS; Inniss, A; Ju, H; Kuo, YF; Reyes-Ortiz, CA | 1 |
| Grimm, J; Kaittanis, C; Perez, JM; Santra, S | 1 |
| Cao, SL; Zhao, B; Zhao, J; Zheng, XL | 1 |
| Kularatne, SA; Low, PS | 2 |
| Bostick, RM; Flanders, WD; Friedman, JM; Yang, Q | 1 |
| Dyson, PJ; Fei, Z; Lu, Q; Meng, L; Zhang, X | 1 |
| Gong, S; Grailer, JJ; Pilla, S; Prabaharan, M; Steeber, DA | 1 |
| Chen, X; Jing, X; Lu, T; Sun, J; Zhang, P | 1 |
| Choi, SW; Friso, S; Kim, KC | 1 |
| Amitay, Y; Gabizon, A; Gorin, J; Mak, L; Shmeeda, H; Tzemach, D; Zalipsky, S | 1 |
| Hansen, MJ; Kleindl, P; Kularatne, SA; Leamon, CP; Low, PS; Qi, L; Thomas, M | 1 |
| Klein, PJ; Leamon, CP; Li, J; LoRusso, P; Messmann, RA; Morgenstern, D; Sausville, EA | 1 |
| Harada, H; Hiraoka, M; Inoue, S; Kuramochi, Y; Matsuoka, H; Miki, K; Nayak, RR; Ohe, K; Oride, K | 1 |
| McGauran, A | 1 |
| An, L; Chen, X; Deng, D; Gu, Y; Liu, F; Qian, Z; Zhang, J | 1 |
| Arnesen, E; Bønaa, KH; Ebbing, M; Meyer, K; Nilsen, DW; Njølstad, I; Nordrehaug, JE; Nygård, O; Rasmussen, K; Refsum, H; Tverdal, A; Ueland, PM; Vollset, SE | 1 |
| Colditz, GA; Drake, BF | 1 |
| Cheng, Z; Thorek, DL; Tsourkas, A | 1 |
| Carey, JR; Chen, CY; Chen, JS; Ke, JH; Lin, JJ; Wang, LF | 1 |
| Arote, RB; Cho, CS; Cho, MH; Hwang, SK; Jere, D; Jiang, HL; Kim, TH; Kim, YK; Lim, HT | 1 |
| Ashokan, A; Koyakutty, M; Menon, D; Nair, S | 1 |
| Chang, CH; Chang, WH; Hsiue, GH; Lo, CL; Ou, TW; Tsai, CH; Tsai, HC; Yen, TC | 1 |
| Huang, L; Qi, Y; Shen, YM; Sun, Y; Xu, X; Zhang, X; Zhang, Y; Zhu, H | 1 |
| Ashworth, A; Barber, LJ; Burgess, DJ; Lord, CJ; Martin, SA; McCarthy, A; Parry, S | 1 |
| Huang, F; McCormick, CL; York, AW | 1 |
| Chang, J; Gong, X; Liang, X; Niu, R; Song, T; Wang, H; Zhao, P | 1 |
| Leonov, AP; Wei, A; Wei, Q | 1 |
| GREENE, RR; PECKHAM, BM | 1 |
| KRACKE, RR; RISER, WH | 1 |
| Achilefu, S; Chen, X; Deng, D; Gu, Y; Liu, F; Qian, Z | 1 |
| McEwan, J; McTavish, K; Russell-Jones, G | 1 |
| Busto, U; Greenberg, ML; Grupp, SG; Koren, G; Lanctôt, KL; Nulman, I; Ray, JG | 1 |
| Chen, Y; Li, K; Li, S; Lu, X; Mello, CM; Nguyen, HG; Niu, Z; Wang, Q; You, S | 1 |
| Duthie, SJ | 2 |
| Hauner, H | 1 |
| Byers, T | 1 |
| Hayashi, K; Moriya, M; Ono, K; Sakamoto, W; Sawada, M; Suzuki, H; Yogo, T | 1 |
| Binulal, NS; Manzoor, K; Menon, D; Mony, U; Nair, S; Narayanan, S | 1 |
| Hattori, Y | 1 |
| Jia, J; Lai, Y; Ma, Y; Sun, L; Weng, J; Zhang, Z | 1 |
| Canal, F; Pasut, G; Schiavon, O; Vicent, MJ | 1 |
| Chang, Y; Fang, X; Jiang, W; Li, Y; Liu, S; Pan, S; Wang, J; Wang, YA; Zhao, Y | 1 |
| Hwang, T; Kang, E; Kim, JH; Kwon, OJ; Lee, JM; Park, H; Park, Y; Yun, CO | 1 |
| Colditz, GA; Wei, EK; Wolin, KY | 1 |
| Acosta, G; Aune, D; Boffetta, P; De Stefani, E; Deneo-Pellegrini, H; Mendilaharsu, M; Ronco, AL | 1 |
| Low, PS; Xia, W | 1 |
| Marks, R | 1 |
| Lee, RJ; Li, H; Wu, J; Xiong, S; Yu, B | 1 |
| Gong, S; Grailer, JJ; Hurley, SA; Javadi, A; Rowland, IJ; Steeber, DA; Yang, X | 1 |
| Juzeniene, A; Moan, J | 1 |
| Gulati, N; Jayasundar, R; Kotnala, RK; Koul, V; Rastogi, R; Sharma, U | 1 |
| Benito, M; Blanco, MD; Guerrero, S; Katime, I; Muñíz, E; Olmo, R; Teijón, C; Teijón, JM | 1 |
| Asselain, B; Laplaige, P; Ray-Coquard, I; Urbieta, M; Vey, N | 1 |
| Armitage, J; Bennett, D; Bønaa, KH; Clarke, R; Collins, R; Gaziano, JM; Guarino, P; Halsey, J; Jamison, R; Lewington, S; Lonn, E; Manson, JE; Mir, F; Nygård, O; Peto, R; Spence, JD | 1 |
| Tice, JA | 1 |
| Fei, X; Gu, Y; Meng, Q; Wang, Y; Zhang, B | 1 |
| Ametamey, SM; Groehn, V; Honer, M; Müller, C; Ross, TL; Schibli, R | 1 |
| Balan, L; Geszke, M; Korczynski, J; Lulek, J; Medjahdi, G; Moritz, M; Murias, M; Schneider, R | 1 |
| Baron, JA; Mason, JB | 1 |
| de Lima, MC; Duarte, S; Faneca, H | 1 |
| Guo, M; Liu, K; Liu, X; Que, C; Wang, C; Yan, H | 1 |
| Bennett, D; Clarke, R; Halsey, J; Lewington, S | 1 |
| Gajbhiye, V; Jain, K; Jain, NK; Kesharwani, P; Tekade, RK | 1 |
| Cao, W; Wang, Y; Zhou, J; Zhu, L | 1 |
| Chen, Z; Deng, F; Fan, C; Fan, H; Gao, W; Li, M | 1 |
| Jiang, Q; Li, C; Shi, P; Tang, G; Wang, Q; Xu, F; Yang, W | 1 |
| Müller, C; Schibli, R | 1 |
| Cattel, L; Dosio, F; Milla, P | 1 |
| Bigall, NC; Di Corato, R; Dorfs, D; Genovese, A; Manna, L; Marotta, R; Pellegrino, T; Ragusa, A | 1 |
| Fadeel, B; Garcia-Bennett, A; Nees, M | 1 |
| Cao, X; Guo, R; Shen, M; Shi, X; Wang, Y | 1 |
| Kamei, DT; Liu, CT; Nafisi, PM; Quinlan, DS; Yoon, DJ | 1 |
| Chen, Y; Feng, L; Qu, X; Ren, J; Song, Y | 1 |
| Hazari, PP; Kumar, N; Mishra, AK; Mishra, G | 1 |
| Apeland, T; Bates, CJ; Drabløs, PA; Hervig, T; Mansoor, MA; Stakkestad, JA; Wentzel-Larsen, T | 1 |
| Gui, S; Huang, J; Tang, X; Xue, Y; Yu, J; Zhang, X; Zhang, Y | 1 |
| Barberi-Heyob, M; Bastogne, T; François, A; Frochot, C; Guillemin, F; Morosini, V; Schneider, R | 1 |
| Kang, E; Kim, JH; Kwon, OJ; Park, HK; Park, Y; Yun, CO | 1 |
| Bugaj, AM | 1 |
| Carrasco, MP; Enyedy, EA; Krupenko, NI; Krupenko, SA; Martinelli, A; Nuti, E; Rossello, A; Santamaria, S; Santos, MA; Tuccinardi, T | 1 |
| Hu, X; Li, X; Liu, S; Liu, T; Qian, Y; You, Y; Zhang, G | 1 |
| Belfield, KD; Bondar, MV; Komatsu, M; Morales, AR; Urakami, T; Wang, X; Zhang, L | 1 |
| Khambati, H; Kolhatkar, R; Lote, A | 1 |
| Andò, S; Brunelli, E; Casula, MF; Maris, P; Morelli, C; Nagy, JB; Panno, ML; Pasqua, L; Perrotta, E; Perrotta, I; Sisci, D; Tagarelli, A; Testa, F; Versace, C | 1 |
| Chen, ZG; Giannakakou, P; Gjyrezi, A; Koenig, L; Li, J; Nie, S; Shin, DM; Shin, EH; Tighiouart, M; Wang, X; Wang, Y | 1 |
| Gregory, JF; James, SJ; Liu, A; Neuhouser, ML; Nijhout, HF; Reed, MC; Shane, B; Ulrich, CM | 1 |
| Andersen, R; Antoine, JM; Chiodini, A; Finglas, P; Hoekstra, J; Kardinaal, A; Nordmann, H; Pekcan, G; Pentieva, K; Sanders, TA; van den Berg, H; van Kranen, H; Verhagen, H | 1 |
| Al-Kattan, A; Bernad, J; Bordère, J; Charvillat, C; Dexpert-Ghys, J; Drouet, C; Dufour, P; Girod-Fullana, S; Pipy, B; Santran, V; Ternet-Fontebasso, H | 1 |
| Lambrecht, FY; Onursal, M; Ozgur, A | 1 |
| Ding, RM; He, H; Li, J | 1 |
| Cheng, Z; Elias, DR; Hammer, DA; Johnston, ED; Kamat, NP; Poloukhtine, A; Popik, V; Tsourkas, A | 1 |
| Kaittanis, C; Perez, JM; Santiesteban, OJ; Santra, S | 1 |
| Bai, F; Bai, G; Cao, MR; Hou, J; Kong, DL; Li, X; Shi, Q; Tang, Y; Yang, CH; Zhang, Q | 1 |
| Meegan, MJ; O'Boyle, NM | 1 |
| Perez, JM; Santra, S | 1 |
| Denny, W; Garg, S; Kendall, J; Talekar, M | 1 |
| Baggott, JE; Oster, RA; Tamura, T | 1 |
| Chang, WH; Chen, YC; Hsieh, WY; Wang, SJ | 1 |
| Harada, H; Hiraoka, M; Kimura, A; Kuramochi, Y; Matsuoka, H; Miki, K; Ohe, K; Oride, K | 1 |
| Amiano, P; Biessy, C; Boutron-Ruault, MC; Chajès, V; Chuang, SC; Clavel-Chapelon, F; Crowe, F; Dahm, CC; Engeset, D; Ericson, U; Feller, S; Freisling, H; Halkjær, J; Khaw, KT; María Huerta, J; Mattiello, A; Nicolas, G; Orfanos, P; Palli, D; Park, JY; Peeters, PH; Romieu, I; Ros, MM; Scalbert, A; Skeie, G; Slimani, N; Teucher, B; Trichopoulou, A; Vineis, P; Wallström, P | 1 |
| Bazou, D; Gérard, VA; Gun'ko, YK; Maguire, CM | 1 |
| Butcher, NJ; Minchin, RF | 1 |
| Guan, W; Hu, Z; Huang, Y; Sun, S; Yao, Y; Zhang, C | 1 |
| Low, P; Vlashi, E; Yang, J | 1 |
| Aneja, R; Joshi, HC; Lopus, M; Naik, PK; Vangapandu, SN | 1 |
| Benoit, R; Chiper, M; Chourpa, I; Dubois, P; Hervé-Aubert, K; Kaaki, K; Paillard, A; Saboungi, ML; Shkilnyy, A; Soucé, M | 1 |
| Muller, C | 1 |
| Andreeva, VA; Galan, P; Hercberg, S; Julia, C; Kesse-Guyot, E; Touvier, M | 1 |
| Bailey, LB; Berry, RJ; Crider, KS; Yang, TP | 1 |
| Cavuoto, P; Fenech, MF | 1 |
| Dumitrescu, RG | 1 |
| Eun, JS; Lee, MK; Seo, SY; Yue, Y | 1 |
| Martin-Du Pan, RC; Mercan, D | 1 |
| Huang, C; Jin, Y; Li, D; Tang, Z; Yang, Y; Zhou, S; Zhou, X; Zhou, Y | 1 |
| Cheng, T; Guan, XM; Lan, JF; Liu, XY; Shen, JM; Zhang, HX | 1 |
| Chang, YC; Hsieh, WY; Hsu, CY; Hsu, YH; Lai, PS; Rajan, YC; Syu, WJ; Wang, CH; Yu, HP | 1 |
| Goldman, ID; Visentin, M; Zhao, R | 1 |
| Cartmel, B; Ferrucci, LM; Mayne, ST | 1 |
| Arora, S; Budhiraja, A; Chaudhari, KR; Kumar, R; Malhi, SS; Murthy, RS; Nepali, K; Sohi, H | 1 |
| Baron, JA; Byers, T; Jacobs, ET; Marshall, JR; Martínez, ME | 1 |
| Chen, D; Gao, F; Hao, N; Huang, X; Li, H; Li, L; Liu, H; Liu, T; Peng, B; Tan, L; Tang, F; Wu, X; Yan, C; Yang, L | 1 |
| Kissel, T; Liu, L; Renette, T; Zheng, M | 1 |
| Carrilho, E; Coltro, WK; Gobbi, AL; Lima, RS; Nascente, PA; Piazzetta, MH; Rodrigues-Filho, UP | 1 |
| Bae, BC; Ling, D; Na, K; Park, W | 1 |
| Cai, Z; Chen, Y; Sun, B; Sun, Y; Yu, F; Zhang, H | 1 |
| Fang, X; Han, L; Huang, Y; Qin, J; Shen, M; Wang, J; Yang, VC | 1 |
| Li, L; Liu, A; Liu, R; Liu, W; Nie, N; Ren, L; Tu, Q; Wang, J; Wang, JC; Wang, L; Wang, X; Zhang, Y | 1 |
| Johnson, KJ; Linabery, AM; Ross, JA | 1 |
| Chen, Q; Wei, Y; Wu, B; Xing, D; Zhou, A | 1 |
| Leamon, CP; Vlahov, IR | 1 |
| An, F; Diao, X; Hao, X; Li, W; Liu, Z; Wang, C; Yang, Y; Zhang, X | 1 |
| Jägerstad, M | 1 |
| Byun, Y; Deng, D; Gu, Y; Yang, VC; Zhang, J; Zhu, H | 1 |
| Baker, JR; Choi, SK; Desai, AM; Gam, J; Huang, B; Joice, M; Kotlyar, A; Silpe, JE; Thomas, TP; Zong, H | 1 |
| Ashwanikumar, N; Deepa, G; Kumar, GS; Pillai, JJ | 1 |
| Hong, Y; Liu, Y; Luo, D; Sha, Y; Wang, L; Yang, Y; Zhou, M | 1 |
| Dal Maso, L; Franceschi, S; La Vecchia, C; Levi, F; Malerba, S; Montella, M; Pelucchi, C; Serraino, D; Tavani, A; Zambon, A; Zucchetto, A | 1 |
| Assaraf, YG; Gonen, N | 1 |
| Lagercrantz, H | 1 |
| Achilefu, S; Chen, H; Cui, S; Gu, Y; Li, B; Li, S; Mahounga, DM; Ren, X | 1 |
| Bichelberger, MA; Colin, DY; Masson, JF; Pelletier, JN; Robitaille, R; Zhao, SS | 1 |
| Desmoulin, SK; Gangjee, A; Hou, Z; Matherly, LH | 1 |
| Bruhn, L; Jung, K | 1 |
| Behan, NA; Brooks, SP; Caldwell, D; Green, J; MacFarlane, AJ; Matias, FM | 1 |
| Bever, SL; Edelman, MJ; Forman, KM; Heath, EI; Klein, PJ; Leamon, CP; Li, J; Lorusso, PM; Malburg, LM; Messmann, RA; Pilat, M; Quinn, MF; Sausville, EA | 1 |
| Dhakad, RS; Jain, NK; Tekade, RK | 1 |
| Chen, C; Hou, L; Li, L; Li, Z; Shi, J; Wang, H; Wang, L; Wang, Z; Zhang, C; Zhang, H; Zhang, Z | 1 |
| Bertino, JR; Tedeschi, PM; Vazquez, A | 1 |
| Ai, J; Li, D; Liu, Z; Wang, E; Xu, Y | 1 |
| Fan, J; Liang, X; Liu, L; Ma, X; Sun, Y; Zeng, W; Zhao, Y | 1 |
| Krupenko, NI; Krupenko, SA; Strickland, KC | 1 |
| Fajardo, V; Varela-Moreiras, G | 1 |
| Ametamey, SM; Betzel, T; Fischer, CR; Groehn, V; Krämer, SD; Müller, A; Müller, C; Reber, J; Schibli, R | 1 |
| Kim, JS; Nam, YS; Oh, MH; Park, JY; Park, TG | 1 |
| Choi, SW; Corrocher, R; Friso, S; Girelli, D; Guarini, P; Martinelli, N; Moruzzi, S; Olivieri, O; Pattini, P; Pellegrini, C; Pizzolo, F; Udali, S | 1 |
| Li, Z; Luan, Y; Pang, J; Zhang, L; Zhao, L | 1 |
| Bunout, D; de la Maza, MP; Hirsch, S; Miranda, D; Montoya, M; Muñoz, E; Ronco, AM | 1 |
| Mironava, T; Rafailovich, MH; Rigas, B; Simon, M | 1 |
| Li, J; Yin, H; Zhang, Z; Zhao, F | 1 |
| Cui, Y; Huo, Y; Li, J; Qin, X; Shen, L; Sun, N; Wang, B; Wang, X; Xu, X; Zhang, Y | 1 |
| Miller, JW; Ulrich, CM | 1 |
| Armitage, J; Baron, JA; Bennett, D; Bønaa, KH; Clarke, R; Collins, R; den Heijer, M; Ebbing, M; Galan, P; Gaziano, JM; Giovannucci, EL; Guarino, P; Halsey, J; Hankey, GJ; Jamison, R; Lewington, S; Logan, RF; Lonn, E; Manson, JE; Peto, R; Spence, JD; Ueland, PM; Vollset, SE | 1 |
| Guo, ZY; Liu, ZM; Qin, XC; Wan, MM; Yang, BW; Zhang, W | 1 |
| Hao, H; He, F; Huang, C; Ma, Q; Yao, P | 1 |
| Delvenne, P; Humbert, P; Lesuisse, M; Pierard, GE; Pierard-Franchimont, C | 1 |
| Achilefu, S; Cao, J; Deng, D; Du, C; Gu, Y; Shan, L; Tian, J; Wan, S | 1 |
| Alam, S; Chauhan, VS; Kaul, A; Kumar, S; Kundu, GC; Mishra, AK; Panda, JJ | 1 |
| Cao, J; Cui, S; Gu, Y; Qian, Z; Zhu, H | 1 |
| Low, PS; Lu, Y | 2 |
| Ames, BN; Wakimoto, P | 1 |
| Oliveira, L; Pereira Miguel, JM; Pereirinha, A; Reis, MF | 1 |
| Deng, L; Hiou-Tim, F; James, SJ; Li, E; Melnyk, S; Oakes, C; Pogribny, I; Rozen, R; Sibani, S; Trasler, J | 1 |
| Bailey, LB; Kauwell, GP; Rampersaud, GC | 2 |
| Kornek, GV; Locker, GJ; Mader, RM; Pluschnig, U; Scheithauer, W; Steger, GG; Wenzel, C | 1 |
| Allen, R; Bunn, PA; Calvert, AH; Hanauske, AR; Niyikiza, C; Paoletti, P; Rusthoven, JJ | 1 |
| Boer, JM; Cornelisse, CJ; Feskens, EJ; Heijmans, BT; Kromhout, D; Slagboom, PE; Suchiman, HE; Westendorp, RG | 1 |
| Lökk, J | 1 |
| Blakemore, J; Dancik, C; Kaleko, M; Mulgrew, K; Nyanguile, O; Stevenson, SC | 1 |
| Bae, YH; Lee, ES; Na, K | 1 |
| Lin, DX; Miao, XP | 1 |
| PAOLINO, W | 1 |
| BROQUIST, HP | 1 |
| DIETRICH, LS; KREAM, J; SHAPIRO, DM | 1 |
| HUANT, E | 1 |
| GIRDWOOD, RH | 1 |
| HAEHNER, E; LUDES, H | 1 |
| KOCZOCIK-PRZEDPELSKA, J | 1 |
| FABIAN, G; LINKE, H | 1 |
| FRIEDMAN, F; HARNLY, MH; KOPAC, MJ | 2 |
| LUDES, H; STELLER, J | 1 |
| FUGMANN, RA; SHAPIRO, DM | 1 |
| OFFNER, E | 1 |
| GALARDESCHI, O; SPIGLIATI, P | 1 |
| BACHI, C; COSCIA, GC; ROSSI, M | 1 |
| de CLERCQ, M; TRUHAUT, R | 1 |
| CHAMPY-HATEM, S | 1 |
| CONDIT, PT; OWENS, AH; SHNIDER, BI | 1 |
| BRENNHOVD, I; ENGSETH, A; STOVNER, J | 1 |
| KARLIN, R | 2 |
| BESSIERE, G; PERUS, JP | 1 |
| EINHORN, J; LAGERLOF, B; REIZENSTEIN, P | 1 |
| BERTINO, JR | 2 |
| VOISIN, A | 1 |
| BONNET, PA; DESPIERRES, G; PHELIP, H | 1 |
| JAENICKE, L; WILMANNS, W | 1 |
| BERTINO, JR; HELLMAN, S; IANNOTTI, AT | 1 |
| MISRA, DK | 1 |
| ANDERSON, EP; BROCKMAN, RW | 1 |
| GIRDWOOD, RH; KERSHAW, PW | 1 |
| COSTAKEL, O | 1 |
| BROCKMAN, RW | 1 |
| BIGNOTTI, G; TOGNELLA, S | 1 |
| SCHINDLER, R | 1 |
| BRENA, GP; CAREY, RW; KRANT, MJ | 1 |
| RYDER, RJ | 1 |
| EAKINS, D; FULTON, T; HADDEN, DR | 1 |
| AMIEL, JL; CATTAN, A; MATHE, G; SCHLUMBERGER, JR; SCHNEIDER, M; SCHWARZENBERG, L | 1 |
| EINHORN, J; LAGERLOEF, B; RAO, PB; REIZENSTEIN, PG | 1 |
| CHAUVERGNE, J; HUGUES, A; LACHAPELE, AP; LAGARDE, C | 1 |
| CAVANAGH, D; FERGUSON, JH; MARTIN, DS | 1 |
| DESPIERRES, G | 1 |
| KIM, YS; LOKEN, MK; MARVIN, JF; MOSSER, DG | 1 |
| NICHOL, CA; ROSEN, F | 1 |
| Green, MA; Laforest, R; Lewis, JS; Lewis, MR; Low, PS; Mathias, CJ; Reichert, DE; Sharp, TL; Snyder, PW; Waters, DJ; Welch, MJ; Yang, ZF | 1 |
| Albanes, D; Glynn, SA | 1 |
| Giovannucci, EL; Hu, FB; Jiang, R; Rimm, EB; Rosner, BA; Spiegelman, D; Stampfer, MJ; Willett, WC | 1 |
| Ben-Amotz, D; Jallad, KN; Kennedy, MD; Low, PS; Thompson, DH | 1 |
| Goldman, ID; Zhao, R | 1 |
| Bailey, LB | 1 |
| Czeizel, E; Kalina, A | 1 |
| Green, MA; Ke, CY; Mathias, CJ | 1 |
| Gao, F; Goldman, ID; Hanscom, M; Zhao, R | 1 |
| GOLDBERG, B; GOLDIN, A; GREENSPAN, EM; SCHOENBACH, EB | 1 |
| GOLDIN, A; GREENSPAN, EM; SCHOENBACH, EB | 3 |
| COPELAND, DH; HALE, OM; SALMON, WD; SCHAEFER, AE | 1 |
| VIGNOLO-LUTATI, U | 1 |
| CARMICHAEL, N; TAYLOR, A | 1 |
| LEWIS, FJ; TONGEN, LA; WANGENSTEEN, OH | 1 |
| BASERGA, A | 1 |
| Jackman, AL; Theti, DS | 1 |
| Coakley, T; Jay, M; Mumper, RJ; Oyewumi, MO; Yokel, RA | 1 |
| Antony, AC; Low, PS | 1 |
| Elnakat, H; Ratnam, M | 2 |
| Leamon, CP; Reddy, JA | 1 |
| Gawlick, U; Kranz, DM; Orr, BA; Roy, EJ | 1 |
| Heimburger, DC; Johanning, GL; Whiteside, MA | 1 |
| Adjei, AA | 1 |
| Brozek, A; Kunachowicz, H; Nadolna, I; Stoś, K; Szponar, L | 1 |
| Achilefu, S | 1 |
| Stover, PJ | 1 |
| Antony, AC; Guo, L; Jayaram, HN; Roeske, RW; Zhang, Y | 1 |
| Danenberg, PV | 1 |
| Lee, SB; Lee, YM; Park, EK | 1 |
| HARDY, SM; HOWARD, RW; JOYNER, AL | 1 |
| BOUTWELL, RK; BRUSH, MK; RUSCH, HP | 1 |
| DE ROPP, RS | 1 |
| GILMORE, JR | 1 |
| FARBER, S | 2 |
| CRUMRINE, JL; HASS, GM; SLAUGHTER, DP; TAYLOR, SG | 1 |
| GUTENSOHN, MT; KLINE, AP; ROHWEDER, CA | 1 |
| BIESELE, JJ; BURCHENAL, JH; KARNOFSKY, DA; MOORE, AE; STOCK, CC; SUGIURA, K | 1 |
| McEwan, J; McTavish, K; Nowotnik, D; Rice, J; Russell-Jones, G | 1 |
| Brzozowska, A; Roszkowski, W; Sicińska, E | 1 |
| Davis, CD; Uthus, EO | 1 |
| Chattopadhyay, S; Goldman, ID; Wang, Y; Zhao, R | 1 |
| Brink, M; de Bruïne, AP; de Goeij, AF; Goldbohm, RA; Lentjes, MH; Roemen, GM; van den Brandt, PA; van Engeland, M; Weijenberg, MP | 1 |
| Holven, K; Løken, EB; Smeland, S; Staff, AC; Sygnestveit, K; Vollset, SE | 1 |
| Johnson, IT | 1 |
| Baker, JR; Choi, Y | 1 |
| Labhasetwar, V; Vasir, JK | 1 |
| Choi, SW; Mason, JB | 1 |
| Batich, CD; Chatel, D; Dutta, D; Liesenfeld, B; Mericle, RA; Moudgil, BM; Santra, S; Tan, W | 1 |
| Cieplik, J | 1 |
| Hilgenbrink, AR; Low, PS | 1 |
| Choi, SW; Friso, S | 1 |
| Boynton, A; Robien, K; Ulrich, CM | 1 |
| Robien, K | 1 |
| Kim, SY; Lee, SB; Lee, YM; Park, EK | 1 |
| Choi, SW; Jang, H; Mason, JB | 1 |
| Bartholomew, H; Beilby, JP; Divitini, ML; Hung, J; Knuiman, MW; Rossi, E | 1 |
| de Vries, NA; Hooijberg, JH; Jansen, G; Kaspers, GJ; Peters, GJ; Pieters, R | 1 |
| Rahman, A; White, RM | 1 |
| Baker, SD; Chaudhary, AK; Chaudhuri, T; Goetz, A; Hammond, LA; Johnson, RD; Latz, JE; Mita, AC; Molpus, K; Patnaik, A; Rowinsky, EK; Sandler, A; Simms, L; Sweeney, CJ; Takimoto, CH; Tolcher, AW; Villalona-Calero, M | 1 |
| Kelemen, LE | 1 |
| Jammaz, IA; Okarvi, SM | 1 |
| Potter, JD; Ulrich, CM | 2 |
| Jackson, RC; Loparo, KA; Radivoyevitch, T; Sedwick, WD | 1 |
| Müller, C; Schibli, R; Schubiger, PA | 2 |
| Thompson, J | 1 |
| Ametamey, SM; Bettio, A; Brühlmeier, M; Groehn, V; Honer, M; Müller, C; Müller, U; Schibli, R; Schubiger, AP | 1 |
| de Jong, N; Kampman, E; Kloosterman, J; Ocké, MC; Rompelberg, CJ; van Kranen, HJ | 1 |
| Katan, MB; Verhoef, P | 1 |
| Adachi, S; Fukuoka, M; Kudoh, S; Latz, JE; Matsui, K; Nakagawa, K; Negoro, S; Yamamoto, N | 1 |
| Chan, P; Chung, JE; Kurisawa, M; Yang, YY | 1 |
| Lucock, MD | 1 |
| Cornel, MC | 1 |
| Smith, AD | 1 |
| Barale, R; Buda, G; Galimberti, S; Maggini, V; Petrini, M; Rossi, AM | 1 |
| Denz, HA; Fiegl, M; Frick, B; Fuchs, D; Schroecksnadel, K; Winkler, C | 1 |
| Chattopadhyay, S; Goldman, ID; Moran, RG | 1 |
| Anello, G; Benamghar, L; Bosco, P; Calabrese, S; Fontaine, T; Guéant, JL; Guéant-Rodriguez, RM; Romano, A; Spada, RS; Stella, G | 1 |
| D'Incalci, M; Gescher, AJ; Steward, WP | 1 |
| Assaraf, YG | 1 |
| Deng, Y; Hou, Z; Matherly, LH | 1 |
| Bencko, V; Boffetta, P; Brennan, P; Canzian, F; Chabrier, A; Fabianova, E; Foretova, L; Gaborieau, V; Hall, J; Hashibe, M; Hung, RJ; Janout, V; Lissowska, J; Mates, I; McKay, J; Moullan, N; Rudnai, P; Szeszenia-Dabrowska, N; Zaridze, D | 1 |
| Beeram, M; Clark, R; de Bono, J; Forero, L; Forouzesh, B; Hammond-Thelin, LA; Latz, JE; Monroe, P; Patnaik, A; Rowinsky, EK; Schneck, KB; Takimoto, CH; Tolcher, AW; Wood, L | 1 |
| Ahnen, DJ; Allen, JI; Baron, JA; Barry, EL; Beck, GJ; Bond, JH; Bresalier, RS; Burke, CA; Byers, T; Church, TR; Cole, BF; Greenberg, ER; Haile, RW; Mandel, JS; Marcon, N; McKeown-Eyssen, G; Mott, LA; Pearson, LH; Rees, JR; Robertson, DJ; Rothstein, RI; Saibil, F; Sandler, RS; Snover, DC; Summers, RW; Ueland, PM | 1 |
| Houlston, RD; Hubner, RA; Muir, KR | 1 |
| Oakley, GP; Wald, NJ | 1 |
| Doorneweerd, DD; Henne, WA; Low, PS | 1 |
| Reynolds, E | 1 |
| de Jong, M; Forrer, F; Krenning, EP; Müller, C; Schibli, R | 1 |
| Fu, de L; Long, J; Ni, QX; Yang, F | 1 |
| Banin, U; Gabizon, A; Schroeder, JE; Shmeeda, H; Shweky, I | 1 |
| SCOTT, GM | 1 |
| MOORE, AE; STOCK, CC | 1 |
| PHILIPS, FS; THIERSCH, JB | 1 |
| SLAUGHTER, D; TAYLOR, SG | 1 |
| LITTLE, PA; OLESON, JJ | 1 |
| STOCK, CC; THIERSCH, JB | 1 |
| Kim, YI; Refsum, H; Smith, AD | 1 |
| Lopez-Berestein, G; Sanguino, A; Sood, AK | 1 |
| Arpicco, S; Canal, F; Dalla Via, L; Pasut, G; Schiavon, O; Veronese, FM | 1 |
| Bahner, U; Brink, A; Heidland, A; Perna, A; Schmid, U; Schupp, N; Stopper, H; Treutlein, AT | 1 |
| Lawrance, AK; Rozen, R; Stankova, J | 1 |
| Amato, RJ; Edell, SL; Fisher, RE; Messmann, RA; Morgenstern, DE; Oyesiku, NM; Siegel, BA | 1 |
| Brower, V | 1 |
| Magnus, EM | 1 |
| Soreng, AL; Yunis, JJ | 1 |
| Chabner, BA; Clendeninn, NJ; Cowan, KH; Curt, GA; Jolivet, J | 1 |
| Sauberlich, HE | 1 |
| Sauer, H | 1 |
| Ahmed, T; DeGraw, JI; Moccio, DM; Piper, JR; Samuels, LL; Sirotnak, FM; Yagoda, A | 1 |
| Holcenberg, JS | 1 |
| Durán, N; Innocentini, LH | 1 |
| Peck, GL | 1 |
| Allan, RN; Blair, JA; Pheasant, AE; Saleh, AM; Walters, J | 1 |
| McCormack, JJ | 1 |
| Henderson, GB; Huennekens, FM; Suresh, MR; Vitols, KS | 1 |
| Sirtori, C | 1 |
| Hoppner, K; Lampi, B | 1 |
| Chiba, S; Kikuchi, S; Matsumoto, H; Wada, T | 1 |
| Allan, RN; Blair, JA; Pheasant, AE; Saleh, AM | 1 |
| Chaudhuri, PK; Ratnam, M; Ross, JF | 1 |
| Cristiano, RJ; Gottschalk, S; Smith, LC; Woo, SL | 1 |
| Clifford, C; Greenwald, P; Heimendinger, J; Kelloff, G; Pilch, S | 1 |
| Healy, JB | 1 |
| Kushi, LH; Lenart, EB; Willett, WC | 1 |
| Bustamante, A; Henderson, GB; Patel, R; Rideout, DC | 1 |
| Brennan, J; Hageboutros, A; Hudes, GR; LaCreta, FP; McAleer, C; Newman, EM; O'Dwyer, PJ; Ozols, RF; Rogatko, A | 1 |
| Maxwell, RJ | 1 |
| Barrows, LR; Devraj, R; Gangjee, A; Kisliuk, RL; McGuire, JJ; Queener, SF | 1 |
| Jackman, A; Judson, I | 1 |
| Block, G | 1 |
| McNulty, H | 1 |
| Jennings, E | 1 |
| Carlsson, G; Gustavsson, BG; Jaresko, G; Muggia, FM; Spears, CP | 1 |
| Christensen, B | 1 |
| Spigset, O | 1 |
| Fjeldstrup, A | 1 |
| Doroshow, JH; Groshen, S; Jeffers, S; Johnson, K; Leichman, LP; Muggia, FM; Newman, EM; Synold, TW | 1 |
| Gates, SB; Grindey, GB; Habeck, LL; Mendelsohn, LG; Shackelford, KA; Shih, C; Worzalla, J | 1 |
| Hum, MC; Kamen, BA | 1 |
| Henning, SM; Swendseid, ME | 1 |
| Maclennan, R; Nixon, P; Seitz, HK; Watson, RR | 1 |
| Tinkle, M | 1 |
| van den Berg, H; van Poppel, G | 1 |
| Jackman, AL; Takemura, Y | 1 |
| Cheng, CC; Connolly, T; Cowan, KH; Moscow, JA; Myers, TG; Paull, K | 1 |
| Chazal, M; Chéradame, S; Etienne, MC; Fischel, JL; Formento, P; Guillot, T; Milano, G | 1 |
| Brienza, S; Cvitkovic, E; Raymond, E; Soulié, P | 1 |
| Brönstrup, A; Pietrzik, K | 1 |
| Hall, JG; Solehdin, F | 1 |
| Byers, TE; Ford, ES; Giles, WH | 1 |
| Boddy, A; Calvert, AH; Laohavinij, S; Newell, DR; Taylor, GA; Wedge, SR | 1 |
| Low, PS; Reddy, JA | 1 |
| Ubbink, JB | 1 |
| Glade, MJ | 1 |
| Dreosti, IE | 1 |
| Ames, BN | 1 |
| Bertino, JR; Trippett, TM | 1 |
| Bailey, LB; Gregory, JF | 1 |
| Alth, G; Dobrowsky, W; Jindra, RH; Kolbabek, H; Kubin, A | 1 |
| Kennedy, MD; Low, PS; Lowe, DA; Lu, JY | 1 |
| Grant, S; Kyle, B; Moran, R; Poplin, EA; Roberts, JD; Spicer, DV; Synold, T; Tombes, MB | 1 |
| Jeanteur, P | 1 |
| Jacob, RA | 2 |
| Little, J | 1 |
| Green, T; O'Connor, DL; Picciano, MF | 1 |
| Schöffski, O | 1 |
| Choi, SW; Mason, JB; Selhub, J; Stern, LL | 1 |
| Backus, HH; Jansen, G; Molders, N; Padrón, JM; Peters, GJ; Pinedo, HM; van Der Wilt, CL; van Groeningen, CJ; Wouters, D | 1 |
| Frenkel, EP; Yardley, DA | 1 |
| Benz, CC; Drummond, DC; Hong, K; Kirpotin, DB; Park, JW | 1 |
| Mathers, JC | 1 |
| Ward, CM | 1 |
| Thurmon, TF | 1 |
| Balińska, M; Brzezińska, A; Wińska, P | 1 |
| Clifford, CK; Greenwald, P; Milner, JA | 1 |
| Archer, MC; Clarkson, TW; Strain, JJ | 1 |
| Herbig, AK; Stover, PJ; Suh, JR | 1 |
| Ambrosch, A; Boeing, H; Dierkes, J; Jeckel, A; Luley, C; Westphal, S | 1 |
| Delongchamp, RR; Poirier, LA; Sinha, R; Wise, CK | 1 |
| Burris, H; Goetz, A; Hohneker, JA; Johnson, TR; Lampkin, T; Rowinsky, EK; Sailstad, J; Schwartz, G; Smetzer, L; Von Hoff, DD | 1 |
| Gescher, AJ; O'Byrne, KJ; Sharma, RA; Steward, WP | 1 |
| Krishnaswamy, K; Madhavan Nair, K | 1 |
| Alink, G; Andersen, R; Braesco, V; Crews, H; Holst, B; Maiani, G; Ovesen, L; Scotter, M; Solfrizzo, M; van den Berg, R; Verhagen, H; Williamson, G | 1 |
| Gaté, L; Machover, D; Tapiero, H; Tew, KD | 1 |
| Conwill, D; Penman, A | 1 |
| Bunn, PA; Calvert, H | 1 |
| Bessodes, M; Hofland, HE; Iginla, S; Leamon, CP; Masson, C; Osetinsky, I; Reddy, JA; Scherman, D; Wils, P | 1 |
| Duan, W; Kruman, II; Mattson, MP | 1 |
| Hayek, M; Kim, YI; Mason, JB; Meydani, SN | 1 |
| Fairfield, KM; Fletcher, RH | 1 |
| Anderson, DE; Greenwald, P; McDonald, SS; Milner, JA | 1 |
| Levi, RN; Waxman, S | 1 |
| Ashe, H; Clark, B; Conklin, K; Dunlap, A; Halpern, BC; Halpern, JA; Halpern, R; Hardy, D; Smith, RA; Sperling, L; Stea, B | 1 |
| Cocconi, G; Mori, P; Salvadori, C; Tedeschi, R | 1 |
| Goldin, A | 1 |
| McQueen, EG | 1 |
| Henderson, GB; Huennekens, FM; Vitols, KS | 1 |
| Cheng, YC; Grindey, GB | 1 |
| Chiba, S; Kikuchi, S; Matsumoto, H | 1 |
| Grzelakowska-Sztabert, B | 1 |
| Dickson, VL; Eichner, ER; McDonald, CR | 1 |
| Hanley, SA; McBride, JA; Thong, KL | 1 |
| Carter, SK; Kershner, LM | 1 |
| Aceto, L; Gaspari, AL; Masi, G; Natoli, C; Rapani, C; Sica, G; Tinari, N; Trulli, R; Visini, R; Zakaria, M | 1 |
| Seitz, DE | 1 |
| Bertrand, Y; Etienne, MC; Milano, G; Robert, A; Rubie, H; Thyss, A; Touraine, R | 1 |
| Melera, PW | 1 |
| Berman, EM; Werbel, LM | 1 |
| Meyskens, FL | 1 |
| Kampmann, T; Pasarge, E; Rüdiger, HW; Schmidt, A; Tan, TL | 1 |
| Friedman, GD; Selby, JV | 1 |
| Newberne, PM; Rogers, AE | 1 |
| Jolivet, J | 1 |
| Calvert, AH; Jackman, AL; Jones, TR; Newell, DR; Sikora, E; Simmonds, AJ | 1 |
| Fireman, BH; Friedman, GD; Selby, JV | 1 |
| Davis, RE | 1 |
| Bork, E; Hansen, HH; Vest, S | 1 |
| Cavalli, F; D'Incalci, M; Ginier, M; Sessa, C; Willems, Y; Zucchetti, M | 1 |
| Cohen, P; Dix, D | 1 |
| Love, RR; Olsen, SJ | 1 |
| Clerici, M; De Benedictis, R; Labianca, R; Pancera, G; Pastorino, U; Vergani, C | 1 |
| Andondonskaja-Renz, B; Zeitler, HJ | 1 |
| Herbert, V | 1 |
| Eto, I; Krumdieck, CL | 1 |
| Christova-Georgieva, NI; Raikov, ZD; Raikova, ET | 1 |
| Alison, DL; Calvert, AH; Harland, SJ; Jackman, AL; Jones, TR; McElwain, TJ; Newell, DR; Robinson, BA; Siddik, ZH; Wiltshaw, E | 1 |
| Fujimoto, T; Matuoka, H; Murakami, T; Sasaki, K; Taguchi, H; Tanaka, J | 1 |
| Sirotnak, FM | 1 |
| Guo, ZC; Jiang, BD; Sun, TL | 1 |
| Moccio, DM; Samuels, LL; Sirotnak, FM | 1 |
| Reizenstein, P | 1 |
| Gheorghescu, B; Reizenstein, P | 1 |
| Israëls, MC; Noeypatimanond, S; Watson-Williams, EJ | 1 |
| Hansen, HH; Holland, JF; McCall, CB; Selawry, OS | 1 |
| Bertino, JR; Cashmore, AR; Hillcoat, BL | 1 |
| Jansen, SE; Joubert, M; Retief, FP | 1 |
| Gupta, OP | 1 |
| Friedkin, M | 1 |
| Weir, DG | 1 |
| Dayton, PG; Kinkade, JM; Vogler, WR | 1 |
| Bagshawe, KD | 1 |
| Hitchings, GH | 1 |
| Crawford, EJ; Friedkin, M; Plante, LT | 1 |
| McGREGOR McGregor, RF; Nelson, RS; Somayaji, BN | 1 |
| Sims, L | 1 |
| Gizis, F; Rothenberg, SP | 1 |
| Baker, BR; Ho, BT; Lourens, GJ | 1 |
| Klipstein, FA; Smarth, G | 1 |
| Ishihara, S | 1 |
| Buchkremer, G; Martin, H; Nowicki, L | 1 |
| Griffiths, HJ; Nicholson, WJ; O'Gorman, P | 1 |
| Carey, RW; Gailani, SD; Holland, JF; O'Malley, JA | 1 |
| Evans, VJ; Otani, TT; Price, FM; Rotherham, J | 1 |
| Scott, CW | 1 |
| Benso, L; Bonenti, G; Nigro, N | 1 |
| Schmidt, CG | 1 |
| Begemann, H | 1 |
| Bruni, D; Sorrentino, R | 1 |
| Einhorn, J; Reizenstein, P | 1 |
231 review(s) available for folic acid and Benign Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction | 2015 |
An updated review of folate-functionalized nanocarriers: A promising ligand in cancer.
Topics: Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Ligands; Nanoparticles; Neoplasms | 2022 |
The evolving biology of the proton-coupled folate transporter: New insights into regulation, structure, and mechanism.
Topics: Animals; Folic Acid; Folic Acid Antagonists; Humans; Neoplasms; Proton-Coupled Folate Transporter; Transcription Factors; Transcription, Genetic | 2022 |
Emerging roles for folate receptor FOLR1 in signaling and cancer.
Topics: Carbon; Folate Receptor 1; Folate Receptor 2; Folic Acid; Humans; Neoplasms | 2022 |
Interactions between Radiation and One-Carbon Metabolism.
Topics: Carbon; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Methionine; Neoplasms | 2022 |
Pairing structural reconstruction with catalytic competence to evaluate the mechanisms of key enzymes in the folate-mediated one-carbon pathway.
Topics: Animals; Antineoplastic Agents; Carbon; Folic Acid; Humans; Mammals; Methylenetetrahydrofolate Dehydrogenase (NADP); Neoplasms | 2023 |
Progress in the drug encapsulation of poly(lactic-
Topics: Drug Carriers; Folic Acid; Humans; Male; Nanoparticles; Neoplasms; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; United States | 2022 |
A comprehensive review of BET-targeting PROTACs for cancer therapy.
Topics: Folic Acid; Humans; Neoplasms; Proteolysis; Ubiquitin-Protein Ligases | 2022 |
High Plasma Vitamin B12 and Cancer in Human Studies: A Scoping Review to Judge Causality and Alternative Explanations.
Topics: Dietary Supplements; Folic Acid; Humans; Neoplasms; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2022 |
Application of curcumin nanoformulations to target folic acid receptor in cancer: Recent trends and advances.
Topics: Curcumin; Folic Acid; Humans; Neoplasms; Solubility | 2023 |
Folate, folic acid, and chemotherapy-induced toxicities: A systematic literature review.
Topics: Adult; Antineoplastic Agents; Child; Dietary Supplements; Folic Acid; Humans; Neoplasms; Nutritional Status; Vitamin B Complex | 2023 |
The Protective Effect of Maternal Folic Acid Supplementation on Childhood Cancer: A Systematic Review and Meta-analysis of Case-control Studies.
Topics: Dietary Supplements; Folic Acid; Humans; Maternal Health Services; Neoplasms; Protective Agents; Vitamin B Complex | 2019 |
Methionine metabolism in health and cancer: a nexus of diet and precision medicine.
Topics: Animals; Carbon; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Deletion; Histones; Humans; Methionine; Neoplasms; Nutritional Sciences; Oxidation-Reduction; Polyamines; Precision Medicine; RNA | 2019 |
Targeting strategies for superparamagnetic iron oxide nanoparticles in cancer therapy.
Topics: Animals; Antineoplastic Agents; Drug Carriers; Folic Acid; Humans; Hyaluronic Acid; Magnetic Iron Oxide Nanoparticles; Neoplasms; Peptides | 2020 |
Folate-conjugated nanovehicles: Strategies for cancer therapy.
Topics: Animals; Antineoplastic Agents; Dendrimers; Drug Delivery Systems; Folate Receptor 1; Folic Acid; Humans; Liposomes; Molecular Targeted Therapy; Nanostructures; Neoplasms; Tumor Microenvironment | 2020 |
Targeting metabolic dependencies in pediatric cancer.
Topics: Amino Acids; Antineoplastic Agents; Child; Folic Acid; Glycolysis; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; NAD; Neoplasms; Oxidative Phosphorylation; Polyamines | 2020 |
Exploiting the folate receptor α in oncology.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Endometrial Neoplasms; Female; Fluorescent Dyes; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; Humans; Immunoconjugates; Immunologic Factors; Immunotherapy, Adoptive; Lung Neoplasms; Maytansine; Mesothelioma; Molecular Imaging; Molecular Targeted Therapy; Neoplasms; Optical Imaging; Ovarian Neoplasms; Radionuclide Imaging; Theranostic Nanomedicine; Tubulin Modulators | 2020 |
Dietary modifications for enhanced cancer therapy.
Topics: Amino Acids; Animals; Diet; Dietary Supplements; Fasting; Fatty Acids; Folic Acid; Fructose; Glucose; Humans; Neoplasms; Nutritional Status | 2020 |
Folate pathways mediating the effects of ethanol in tumorigenesis.
Topics: Animals; Carcinogenesis; Diet; Ethanol; Folic Acid; Folic Acid Deficiency; Humans; MicroRNAs; Neoplasms; Oxidative Stress; Risk Factors | 2020 |
Genetic, epigenetic and genomic mechanisms of methionine dependency of cancer and tumor-initiating cells: What could we learn from folate and methionine cycles.
Topics: Cell Line, Tumor; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Methionine; Neoplasms; Neoplastic Stem Cells; Vitamin B 12 | 2020 |
Overview of Dual-Acting Drug Methotrexate in Different Neurological Diseases, Autoimmune Pathologies and Cancers.
Topics: Autoimmune Diseases; Folic Acid; Humans; Methotrexate; Neoplasms; Nervous System Diseases; Pharmaceutical Preparations | 2020 |
Role of amino acids in regulation of ROS balance in cancer.
Topics: Amino Acids; Animals; Ferroptosis; Folic Acid; Humans; Metabolic Networks and Pathways; Neoplasms; Oxidative Stress; Reactive Oxygen Species | 2020 |
An outlook on procedures of conjugating folate to (co)polymers and drugs for effective cancer targeting.
Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Polymers | 2020 |
Characterization of soluble folate receptors (folate binding proteins) in humans. Biological roles and clinical potentials in infection and malignancy.
Topics: Animals; Biomarkers; Body Fluids; Disease Susceptibility; Folate Receptor 1; Folate Receptor 2; Folic Acid; Granulocytes; Host-Pathogen Interactions; Humans; Immunity, Innate; Infections; Milk; Neoplasms; Protein Binding | 2020 |
Antitumoral Properties of the Nutritional Supplement Ocoxin Oral Solution: A Comprehensive Review.
Topics: Amino Acids; Animals; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cinnamomum zeylanicum; Dietary Supplements; Disease Models, Animal; Drug Evaluation, Preclinical; Folic Acid; Glucosamine; Glycyrrhiza; Humans; Neoplasms; Pantothenic Acid; Plant Extracts; Sucrose; Tea; Vitamin B 12; Vitamin B 6; Zinc Sulfate | 2020 |
Association between Dietary Intake of Folate and the Risks of Multiple Cancers in Chinese Population: A Dose-Response Meta-Analysis of Observational Studies.
Topics: China; Eating; Female; Folic Acid; Humans; Neoplasms; Prospective Studies; Risk Factors | 2021 |
Potential Benefits and Pitfalls of Histidine Supplementation for Cancer Therapy Enhancement.
Topics: Animals; Dietary Supplements; Folic Acid; Formiminoglutamic Acid; Histidine; Humans; Leukemia; Methotrexate; Neoplasms | 2020 |
Folate-mediated one-carbon metabolism: a targeting strategy in cancer therapy.
Topics: Aminohydrolases; Animals; Carbon; Cell Survival; DNA Methylation; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Molecular Targeted Therapy; Multifunctional Enzymes; Neoplasms | 2021 |
Ocoxin as a complement to first line treatments in cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Chemoradiotherapy; Clinical Trials as Topic; Drug Resistance, Neoplasm; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Neoplasms; Pantothenic Acid; Plant Extracts; Radiation Injuries; Radiation Tolerance; Treatment Outcome; Vitamin B 12; Vitamin B 6; Zinc Sulfate | 2021 |
Therapeutic targeting of the mitochondrial one-carbon pathway: perspectives, pitfalls, and potential.
Topics: Carbon; Folic Acid; Humans; Lymphoma, T-Cell; Metabolic Networks and Pathways; Mitochondria; Neoplasms | 2021 |
The role of biofactors in the prevention and treatment of age-related diseases.
Topics: Aged; Cardiovascular Diseases; Dementia; Diabetes Mellitus; Dietary Fiber; Dietary Supplements; Epigenesis, Genetic; Fatty Acids, Omega-3; Folic Acid; Humans; Neoplasms; Non-alcoholic Fatty Liver Disease; Thiamine; Thioctic Acid; Vitamin D; Vitamin E | 2021 |
The Concept of Folic Acid in Health and Disease.
Topics: Animals; Brain; Embryonic Development; Folic Acid; Folic Acid Deficiency; Humans; Neoplasms; Precancerous Conditions | 2021 |
Arsenic toxicity and epimutagenecity: the new LINEage.
Topics: Arsenic; Arsenic Poisoning; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Environmental Exposure; Epigenesis, Genetic; Folic Acid; Genome, Human; Humans; Long Interspersed Nucleotide Elements; Neoplasms; Promoter Regions, Genetic; S-Adenosylmethionine | 2017 |
A Nanotechnology-based Strategy to Increase the Efficiency of Cancer Diagnosis and Therapy: Folate-conjugated Gold Nanoparticles.
Topics: Animals; Folic Acid; Gold; Humans; Metal Nanoparticles; Nanomedicine; Neoplasms; Organogold Compounds | 2017 |
Safety of folic acid.
Topics: Animals; Cognitive Dysfunction; Diabetes Mellitus; Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Hypersensitivity; Infant, Newborn; Male; Maximum Tolerated Dose; Neoplasms; Neural Tube Defects; No-Observed-Adverse-Effect Level; Pregnancy; Risk Factors; Safety; Thyroid Diseases; United States; United States Food and Drug Administration | 2018 |
Folic acid, one-carbon metabolism & childhood cancer.
Topics: Antineoplastic Agents; Carbon; Child; Dietary Supplements; Folic Acid; Humans; Mutation; Neoplasms | 2017 |
Targeting the Folate Receptor: Improving Efficacy in Inorganic Medicinal Chemistry.
Topics: Antineoplastic Agents; Chemistry, Pharmaceutical; Cisplatin; Contrast Media; Coordination Complexes; Drug Carriers; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms | 2018 |
Cancer Targeting and Drug Delivery Using Carbon-Based Quantum Dots and Nanotubes.
Topics: Antineoplastic Agents; Deoxycytidine; Doxorubicin; Drug Carriers; Drug Liberation; Fluorescent Dyes; Folic Acid; Gemcitabine; Humans; Hyaluronic Acid; Molecular Targeted Therapy; Nanotubes, Carbon; Neoplasms; Quantum Dots; Surface Properties; Transferrin | 2018 |
Folate and Its Impact on Cancer Risk.
Topics: Folic Acid; Folic Acid Deficiency; Humans; Meta-Analysis as Topic; Neoplasms; Risk Factors | 2018 |
Loss of ALDH1L1 folate enzyme confers a selective metabolic advantage for tumor progression.
Topics: Aldehyde Dehydrogenase; Apoptosis; Disease Progression; DNA Methylation; Folic Acid; Humans; Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; RNA Interference; Signal Transduction; Tumor Suppressor Protein p53 | 2019 |
Disturbed homocysteine metabolism is associated with cancer.
Topics: Alleles; Animals; Cystathionine beta-Synthase; Disease Susceptibility; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Metabolic Networks and Pathways; Neoplasms; Polymorphism, Genetic; Risk Factors; Sulfur; Thromboembolism | 2019 |
DHFR Inhibitors: Reading the Past for Discovering Novel Anticancer Agents.
Topics: Animals; Antineoplastic Agents; Drug Discovery; Drug Evaluation, Preclinical; Folic Acid; Folic Acid Antagonists; Humans; Neoplasms; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2019 |
Folic acid functionalized nanoparticles as pharmaceutical carriers in drug delivery systems.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Evaluation, Preclinical; Folic Acid; Humans; Nanoparticles; Neoplasms | 2019 |
Role of Key Micronutrients from Nutrigenetic and Nutrigenomic Perspectives in Cancer Prevention.
Topics: Ascorbic Acid; Fatty Acids, Unsaturated; Folic Acid; Humans; Micronutrients; Neoplasms; Nutrigenomics; Prebiotics; Probiotics; Risk Assessment; Selenium; Vitamin A; Vitamin D | 2019 |
[Nutrition as an epigenetic factor in develops of cancer].
Topics: Diet; Epigenesis, Genetic; Folic Acid; Humans; Incidence; Isothiocyanates; Neoplasms; Polyphenols; Prevalence; Selenium; Spain; Vitamin D; Vitamins | 2019 |
DNA methylation and cancer development: molecular mechanism.
Topics: Animals; Carcinogenesis; DNA Methylation; Folic Acid; Histones; Humans; Mutation; Neoplasms | 2013 |
Folate: metabolism, genes, polymorphisms and the associated diseases.
Topics: Biological Transport; Depression; Down Syndrome; Folic Acid; Humans; Neoplasms; Polymorphism, Genetic; Vascular Diseases | 2014 |
The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.
Topics: Aminopterin; Animals; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Proton-Coupled Folate Transporter; Reduced Folate Carrier Protein | 2014 |
Imaging the folate receptor on cancer cells with 99mTc-etarfolatide: properties, clinical use, and future potential of folate receptor imaging.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Clinical Trials as Topic; Contrast Media; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Neoplasm Staging; Neoplasms; Organotechnetium Compounds; Positron-Emission Tomography; Technetium; Tomography, Emission-Computed, Single-Photon; Vinca Alkaloids; Whole Body Imaging | 2014 |
Therapeutic perspectives of epigenetically active nutrients.
Topics: Antineoplastic Agents; Coffee; Curcumin; Diet; Epigenesis, Genetic; Folic Acid; Food; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Metabolic Syndrome; Neoplasms; Neurodegenerative Diseases; Phytoestrogens; Polyphenols; S-Adenosylmethionine; Selenium; Trace Elements; Vitamin B 12; Vitamin B Complex; Vitamins | 2015 |
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: epidemiology, metabolism and the associated diseases.
Topics: Diabetes Mellitus; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Infertility; Mental Disorders; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Nervous System Diseases; Polymorphism, Genetic; Psoriasis; Vascular Diseases; Vitamin B 12 | 2015 |
Mechanisms and implications of dual-acting methotrexate in folate-targeted nanotherapeutic delivery.
Topics: Animals; Antimetabolites, Antineoplastic; Dendrimers; Drug Carriers; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Methotrexate; Models, Molecular; Nanoparticles; Neoplasms | 2015 |
Efficient delivery of therapeutic agents by using targeted albumin nanoparticles.
Topics: Albumin-Bound Paclitaxel; Albumins; Antibodies, Monoclonal; Antineoplastic Agents; Clinical Trials as Topic; Drug Delivery Systems; Extracellular Matrix; Folic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Paclitaxel; Transferrin | 2015 |
Pediatric cancer epigenome and the influence of folate.
Topics: Adolescent; Age Factors; Child; Child, Preschool; DNA Methylation; Environment; Epigenesis, Genetic; Epigenomics; Folic Acid; Gene Expression Regulation, Neoplastic; Gene-Environment Interaction; Histones; Humans; Infant; Infant, Newborn; Neoplasms | 2015 |
Antivitamins for Medicinal Applications.
Topics: 4-Hydroxycoumarins; Animals; Anti-Bacterial Agents; Anticoagulants; Antineoplastic Agents; Bacteria; Bacterial Infections; Drug Discovery; Folic Acid; Folic Acid Antagonists; Humans; Indenes; Models, Molecular; Neoplasms; Vitamin B 12; Vitamin K; Vitamins | 2015 |
Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy.
Topics: Drug Carriers; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Micelles; Molecular Targeted Therapy; Nanoparticles; Neoplasms | 2015 |
The Interest of Folic Acid in Targeted Photodynamic Therapy.
Topics: Folic Acid; Humans; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Receptors, Cell Surface | 2015 |
Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Drug Resistance, Neoplasm; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Metabolic Networks and Pathways; Neoplasm Proteins; Neoplasms; Precision Medicine; Signal Transduction; Thymidylate Synthase | 2015 |
Folate-conjugated gold nanoparticle as a new nanoplatform for targeted cancer therapy.
Topics: Animals; Folic Acid; Gold; Humans; Hyperthermia, Induced; Metal Nanoparticles; Molecular Targeted Therapy; Nanomedicine; Neoplasms | 2016 |
Safe use of high intakes of folic acid: research challenges and paths forward.
Topics: Cognition; Diabetes Complications; Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Neoplasms; Neural Tube Defects; Research; Thyroid Diseases; Vitamin B 12 Deficiency | 2016 |
Antibody-targeted nanoparticles for cancer treatment.
Topics: Animals; Antibodies; Aptamers, Nucleotide; Drug Delivery Systems; Folic Acid; Humans; Hyperthermia, Induced; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Single-Chain Antibodies; Theranostic Nanomedicine | 2016 |
Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Homeostasis; Humans; Methylation; Mice; Neoplasms; Peptide Synthases; Polyglutamic Acid; S-Adenosylmethionine; Signal Transduction | 2016 |
Folates as adjuvants to anticancer agents: Chemical rationale and mechanism of action.
Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Folic Acid; Humans; Neoplasms | 2016 |
Imaging biomarker roadmap for cancer studies.
Topics: Biomarkers, Tumor; Clinical Decision-Making; Cost-Benefit Analysis; Fluorodeoxyglucose F18; Folic Acid; Humans; Neoplasms; Organotechnetium Compounds; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Research Design; Selection Bias | 2017 |
Targeting of herbal bioactives through folate receptors: a novel concept to enhance intracellular drug delivery in cancer therapy.
Topics: Antineoplastic Agents; Drug Delivery Systems; Folate Receptor 1; Folic Acid; Humans; Ligands; Molecular Targeted Therapy; Neoplasms; Plants, Medicinal; Receptors, Cell Surface | 2017 |
Folate-mediated chemotherapy and diagnostics: An updated review and outlook.
Topics: Animals; Antineoplastic Agents; Drug Delivery Systems; Drug Liberation; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Molecular Probes; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Theranostic Nanomedicine | 2017 |
Can folate intake reduce arsenic toxicity?
Topics: Arsenic; Arsenic Poisoning; Environmental Exposure; Folic Acid; Humans; Methylation; Neoplasms; Risk Factors; Vitamin B Complex | 2008 |
Tumor detection using folate receptor-targeted imaging agents.
Topics: Animals; Carrier Proteins; Diagnostic Imaging; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Radiopharmaceuticals; Receptors, Cell Surface | 2008 |
Evidence for dietary regulation of microRNA expression in cancer cells.
Topics: Curcumin; Diet; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasms; Tretinoin | 2008 |
Modeling folate, one-carbon metabolism, and DNA methylation.
Topics: Diet; DNA Damage; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Silencing; Humans; Neoplasms; Nutritional Status; Promoter Regions, Genetic | 2008 |
Folic acid supplementation and cancer risk: point.
Topics: Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Folic Acid; Humans; Neoplasm Recurrence, Local; Neoplasms; Primary Prevention | 2008 |
Folate and cancer prevention--where to next? Counterpoint.
Topics: Cell Transformation, Neoplastic; Colorectal Neoplasms; Folic Acid; Genetic Variation; Humans; Neoplasms; Prognosis | 2008 |
Perspectives on obesity and sweeteners, folic acid fortification and vitamin D requirements.
Topics: Dementia; Folic Acid; Folic Acid Deficiency; Fructose; Humans; Neoplasms; Neural Tube Defects; Nutrition Policy; Obesity; Sweetening Agents; Vitamin D; Vitamin D Deficiency | 2008 |
Folate status in various pathophysiological conditions.
Topics: Animals; Cardiovascular Diseases; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Humans; Malabsorption Syndromes; Neoplasms; Nervous System Diseases; Neural Tube Defects | 2008 |
Folate-targeted drug strategies for the treatment of cancer.
Topics: Animals; Carrier Proteins; Clinical Trials as Topic; Drugs, Investigational; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Models, Biological; Molecular Structure; Neoplasms; Receptors, Cell Surface | 2008 |
Too much folate: a risk factor for cancer and cardiovascular disease?
Topics: Adenoma; Cardiovascular Diseases; Chronic Disease; Colorectal Neoplasms; Dietary Supplements; Dose-Response Relationship, Drug; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Neoplasms; Risk Factors | 2009 |
Dendrimers in oncology: an expanding horizon.
Topics: Antineoplastic Agents; Boron Neutron Capture Therapy; Dendrimers; Drug Carriers; Folic Acid; Gene Transfer Techniques; Liposomes; Nanoparticles; Neoplasms; Photochemotherapy; Polyethylene Glycols | 2009 |
New perspectives on folate transport in relation to alcoholism-induced folate malabsorption--association with epigenome stability and cancer development.
Topics: Alcoholism; Biological Transport; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Humans; Models, Biological; Neoplasms | 2009 |
Targeted delivery systems for oligonucleotide therapeutics.
Topics: Animals; Antibodies, Monoclonal; Carrier Proteins; Drug Carriers; Drug Delivery Systems; Drug Stability; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Vectors; Humans; Immunoconjugates; Ligands; Lipoproteins; Liposomes; Mice; Neoplasms; Oligonucleotides; Oligonucleotides, Antisense; Peptides; Receptors, Cell Surface; RNA, Small Interfering; Tissue Distribution; Transferrin | 2009 |
[Folate receptor-mediated antitumor drugs].
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Receptors, Cell Surface | 2009 |
Folate-targeted therapeutic and imaging agents for cancer.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Diagnostic Imaging; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Receptors, Cell Surface | 2009 |
Role of the MTHFR polymorphisms in cancer risk modification and treatment.
Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Fluorouracil; Folic Acid; Genetic Predisposition to Disease; Humans; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Polymorphism, Single Nucleotide; Risk Factors | 2009 |
DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging.
Topics: Aging; Animals; DNA Methylation; Embryonic Development; Epigenesis, Genetic; Female; Folic Acid; Genomic Imprinting; Humans; Longevity; Mice; Neoplasms; Pregnancy | 2009 |
Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis.
Topics: Animals; Carcinoma; Colonic Neoplasms; DNA Damage; DNA Methylation; DNA Repair; Epistasis, Genetic; Folic Acid; Folic Acid Deficiency; Humans; Models, Biological; Neoplasms | 2011 |
[Nutritional medicine 2010].
Topics: Diabetes Mellitus, Type 2; Diabetes, Gestational; Evidence-Based Medicine; Feeding Behavior; Female; Folic Acid; Fruit; Humans; Infant, Newborn; Life Style; Neoplasms; Nutrition Disorders; Pregnancy; Vegetables | 2010 |
Development of non-viral vector for cancer gene therapy.
Topics: Carrier Proteins; Cations; Cholesterol; DNA; Folate Receptors, GPI-Anchored; Folic Acid; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Liposomes; Nanoparticles; Neoplasms; Plasmids; Polysorbates; Receptors, Cell Surface; RNA, Small Interfering; Transfection | 2010 |
Time course of risk factors in cancer etiology and progression.
Topics: Alcohol Drinking; Breast Neoplasms; Colorectal Neoplasms; Diet; Disease Progression; Female; Folic Acid; Humans; Lung Neoplasms; Male; Neoplasms; Prognosis; Prostatic Neoplasms; Risk Factors; Smoking | 2010 |
Folate-targeted therapies for cancer.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Drug Carriers; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Therapy; Humans; Immunotherapy; Ligands; Nanoparticles; Neoplasms; Oligoribonucleotides, Antisense; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Cell Surface; RNA, Small Interfering; Up-Regulation | 2010 |
Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals.
Topics: Biomarkers; Cardiovascular Diseases; Cause of Death; Confidence Intervals; Dietary Supplements; Folic Acid; Homocysteine; Humans; Incidence; Neoplasms; Randomized Controlled Trials as Topic; Stroke; Treatment Failure; Vitamin B Complex | 2010 |
Epigenetic modifications and human pathologies: cancer and CVD.
Topics: Cardiovascular Diseases; Diet; DNA Methylation; Epigenesis, Genetic; Epigenomics; Flavonoids; Folic Acid; Humans; Neoplasms; Phenols; Phytotherapy; Polyphenols; Proto-Oncogenes; Vitamin B Complex | 2011 |
Homocysteine and vascular disease: review of published results of the homocysteine-lowering trials.
Topics: Cause of Death; Clinical Trials as Topic; Dietary Supplements; Down-Regulation; Folic Acid; Homocysteine; Humans; Neoplasms; Vascular Diseases; Vitamin B Complex | 2011 |
EC-145, a folate-targeted Vinca alkaloid conjugate for the potential treatment of folate receptor-expressing cancers.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Approval; Drug Evaluation, Preclinical; Female; Folic Acid; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Structure-Activity Relationship; Vinca Alkaloids | 2010 |
Intracellular trafficking considerations in the development of natural ligand-drug molecular conjugates for cancer.
Topics: Antineoplastic Agents; Biological Transport, Active; Biomedical Engineering; Diphtheria Toxin; Doxorubicin; Drug Carriers; Epidermal Growth Factor; ErbB Receptors; Exotoxins; Folic Acid; Folic Acid Transporters; Humans; Interleukin-13; Ligands; Models, Biological; Neoplasms; Receptors, Interleukin-13; Receptors, Transferrin; Ricin; Signal Transduction; Transferrin; Transforming Growth Factor alpha | 2011 |
Targeted photodynamic therapy--a promising strategy of tumor treatment.
Topics: Aptamers, Nucleotide; Drug Carriers; Folic Acid; Humans; Nanoparticles; Neoplasms; Peptides; Photochemotherapy; Photosensitizing Agents | 2011 |
Active tumor targeting of nanomaterials using folic acid, transferrin and integrin receptors.
Topics: Acrylamides; Animals; Antineoplastic Agents; Dendrimers; Drug Delivery Systems; Folic Acid; Humans; Integrin alphaVbeta3; Liposomes; Nanoparticles; Neoplasms; Transferrin | 2011 |
[Research progress of polyamidoamine dendrimer in targeting drug delivery system].
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Biotin; Dendrimers; Drug Carriers; Drug Delivery Systems; Folic Acid; Gene Transfer Techniques; Humans; Ligands; Neoplasms; Polyamines; Polyethylene Glycols; Transferrin | 2011 |
Designed multiple ligands for cancer therapy.
Topics: Antineoplastic Agents; Aromatase Inhibitors; Biochemical Phenomena; Drug Design; Folic Acid; Humans; Ligands; Neoplasms; Protein Kinase Inhibitors; Signal Transduction; Topoisomerase Inhibitors | 2011 |
Targeting of nanoparticles in cancer: drug delivery and diagnostics.
Topics: Albumins; Animals; Antineoplastic Agents; Aptamers, Nucleotide; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Ligands; Nanoparticles; Nanotechnology; Neoplasms; Transferrin | 2011 |
Meta-analysis of cancer risk in folic acid supplementation trials.
Topics: Dietary Supplements; Female; Folic Acid; Humans; Incidence; Male; Neoplasms; Risk Factors | 2012 |
Arylamine N-acetyltransferase 1: a novel drug target in cancer development.
Topics: Animals; Antineoplastic Agents; Arylamine N-Acetyltransferase; Down-Regulation; Drug Discovery; Epigenesis, Genetic; Folic Acid; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Molecular Structure; Neoplasms; Protein Conformation; Small Molecule Libraries; Substrate Specificity | 2012 |
Folate-linked drugs for the treatment of cancer and inflammatory diseases.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Drug Delivery Systems; Folic Acid; Folic Acid Transporters; Humans; Immunoconjugates; Immunotherapy; Inflammation; Neoplasms | 2012 |
Folate based radiopharmaceuticals for imaging and therapy of cancer and inflammation.
Topics: Animals; Drug Delivery Systems; Drug Design; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Inflammation; Macrophages; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2012 |
Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role.
Topics: Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Folic Acid; Folic Acid Deficiency; Humans; Neoplasms | 2012 |
A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension.
Topics: Animals; Carbon-Sulfur Lyases; Diet; Folic Acid; Humans; Life Expectancy; Methionine; Neoplasms; Phenotype; Purine-Nucleoside Phosphorylase | 2012 |
Epigenetic markers of early tumor development.
Topics: Biomarkers, Tumor; DNA Methylation; Early Detection of Cancer; Epigenesis, Genetic; Estradiol Congeners; Folic Acid; Humans; Neoplasms | 2012 |
The antifolates.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Molecular Targeted Therapy; Neoplasms | 2012 |
Lessons learned from randomized clinical trials of micronutrient supplementation for cancer prevention.
Topics: Animals; Antioxidants; Dietary Supplements; Evidence-Based Medicine; Folic Acid; Humans; Micronutrients; Neoplasms; Randomized Controlled Trials as Topic; Vitamin D | 2012 |
Active drug targeting of disease by nanoparticles functionalized with ligand to folate receptor.
Topics: Animals; Drug Delivery Systems; Folic Acid; Folic Acid Transporters; Humans; Ligands; Nanoparticles; Neoplasms | 2012 |
Engineering folate-drug conjugates to target cancer: from chemistry to clinic.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Models, Biological; Neoplasms; Protein Engineering | 2012 |
Polymer nanoparticles--a novel strategy for administration of Paclitaxel in cancer chemotherapy.
Topics: Antibodies; Antineoplastic Agents, Phytogenic; Aptamers, Nucleotide; Drug Carriers; Folic Acid; Humans; Hydrogen-Ion Concentration; Nanoparticles; Neoplasms; Paclitaxel; Peptides; Polymers; Receptors, Vascular Endothelial Growth Factor | 2012 |
Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance.
Topics: Animals; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Neoplasms; Structure-Activity Relationship | 2012 |
The human proton-coupled folate transporter: Biology and therapeutic applications to cancer.
Topics: Biological Transport; Carcinoma, Non-Small-Cell Lung; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Lung Neoplasms; Mesothelioma; Molecular Targeted Therapy; Neoplasms; Pemetrexed; Proton-Coupled Folate Transporter | 2012 |
Molecular mechanisms underlying the potentially adverse effects of folate.
Topics: Cell Transformation, Neoplastic; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Humans; Male; Neoplasm Metastasis; Neoplasms; Neural Tube Defects; Prostatic Neoplasms; Tetrahydrofolate Dehydrogenase | 2013 |
Folic acid supplementation and cancer risk: a meta-analysis of randomized controlled trials.
Topics: Dietary Supplements; Folic Acid; Humans; Incidence; Neoplasms; Randomized Controlled Trials as Topic; Risk | 2013 |
Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50,000 individuals.
Topics: Carcinogens; Dietary Supplements; Female; Folic Acid; Humans; Incidence; Male; Middle Aged; Neoplasms; Randomized Controlled Trials as Topic | 2013 |
Toxic epidermal necrolysis and antifolate drugs in cancer chemotherapy.
Topics: Folic Acid; Folic Acid Antagonists; Humans; Neoplasms; Skin; Stevens-Johnson Syndrome | 2012 |
Folate-mediated delivery of macromolecular anticancer therapeutic agents.
Topics: Antineoplastic Agents; Carrier Proteins; Drug Carriers; Endocytosis; Enzymes; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Vectors; Humans; Immunotherapy; Macromolecular Substances; Neoplasms; Oligonucleotides; Receptors, Cell Surface; Toxins, Biological | 2002 |
Are vitamin and mineral deficiencies a major cancer risk?
Topics: Animals; Avitaminosis; DNA Damage; Folic Acid; Humans; Neoplasms; Nutritional Physiological Phenomena; Risk Factors; Trace Elements; Vitamin B 12; Vitamin B 6 | 2002 |
Folate: a key to optimizing health and reducing disease risk in the elderly.
Topics: Aged; Biological Availability; Cardiovascular Diseases; Cognition Disorders; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Male; Neoplasms; Nutrition Policy; Risk Factors; United States; Vegetables; Vitamin B 12; Vitamin B 12 Deficiency | 2003 |
Pemetrexed safety and dosing strategy.
Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Homocysteine; Humans; Methylmalonic Acid; Neoplasms; Pemetrexed; Thymidylate Synthase; Vitamin B 12 | 2002 |
News and views on folate and elderly persons.
Topics: Aged; Cardiovascular Diseases; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Mental Disorders; Methylation; Neoplasms; Risk Factors; Vitamin B 12 Deficiency | 2003 |
Folic acid supplements and fortification affect the risk for neural tube defects, vascular disease and cancer: evolving science.
Topics: Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Neoplasms; Neural Tube Defects; Vascular Diseases | 2003 |
[Folate and cancer].
Topics: Animals; DNA Damage; DNA Methylation; DNA Repair; Folic Acid; Folic Acid Deficiency; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Polymorphism, Single Nucleotide | 2003 |
THE MECHANISM OF ACTION OF THE FOLATE ANTAGONISTS IN MAN.
Topics: Enzyme Inhibitors; Folic Acid; Folic Acid Antagonists; Methotrexate; Neoplasms; Oxidoreductases; Pharmacology | 1963 |
[FOLIC ACID METABOLISM AND ONE-CARBON UNITS].
Topics: Avitaminosis; Biochemical Phenomena; Carbon; Coenzymes; Escherichia coli; Folic Acid; Folic Acid Antagonists; Hematology; Humans; Leukemia; Metabolism; Neoplasms | 1963 |
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS).
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Floxuridine; Fluorouracil; Folic Acid; Glutamine; Leukemia L1210; Mercaptopurine; Methotrexate; Mitomycin; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Puromycin; Pyrimidines; Research; RNA; RNA, Neoplasm; Thioguanine; Thiouracil | 1963 |
MECHANISMS OF RESISTANCE TO ANTICANCER AGENTS.
Topics: Alkylating Agents; Antineoplastic Agents; Azaserine; Dactinomycin; DNA; Drug Resistance; Drug Resistance, Microbial; Drug Tolerance; Folic Acid; Humans; Leucine; Metabolism; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Pyrimidines; RNA; Steroids; Tissue Culture Techniques | 1963 |
Folate and cancer: a review of the literature.
Topics: Animals; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Neoplasms; Risk Factors | 1994 |
Resistance to antifolates.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Drug Resistance, Neoplasm; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Neoplasm Proteins; Neoplasms; Receptors, Cell Surface | 2003 |
Folate, methyl-related nutrients, alcohol, and the MTHFR 677C-->T polymorphism affect cancer risk: intake recommendations.
Topics: Adenoma; Alcohol Drinking; Colonic Neoplasms; Folic Acid; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Neoplasms; Nutrition Policy; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12 | 2003 |
[Public health control of hyperhomocysteinemia and its consequences].
Topics: Alzheimer Disease; Canada; Cardiovascular Diseases; Flour; Folic Acid; Food, Fortified; Hematinics; Homocysteine; Humans; Hungary; Hyperhomocysteinemia; Neoplasms; Neural Tube Defects; Primary Prevention; Public Health; Randomized Controlled Trials as Topic; United Kingdom; United States; Vitamin B Complex; Vitamin B Deficiency | 2003 |
The folate receptor as a molecular target for tumor-selective radionuclide delivery.
Topics: Animals; Biomarkers, Tumor; Carrier Proteins; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Pentetic Acid; Radioisotopes; Radiopharmaceuticals; Receptors, Cell Surface; Tomography, Emission-Computed | 2003 |
Folate receptor-targeted drugs for cancer and inflammatory diseases.
Topics: Animals; Carrier Proteins; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Inflammation; Neoplasms; Receptors, Cell Surface | 2004 |
Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy.
Topics: Animals; Carrier Proteins; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Protein Isoforms; Receptors, Cell Surface | 2004 |
Folate-targeted chemotherapy.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Receptors, Cell Surface | 2004 |
Folate-mediated targeting of T cells to tumors.
Topics: Adoptive Transfer; Animals; Carrier Proteins; Cell Line, Tumor; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Receptors, Cell Surface; T-Lymphocytes | 2004 |
Micronutrients and cancer therapy.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Combined Modality Therapy; Drug Synergism; Folic Acid; Humans; Micronutrients; Neoplasms; Treatment Outcome | 2004 |
Pemetrexed (ALIMTA), a novel multitargeted antineoplastic agent.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Neoplasms; Pemetrexed; Platinum Compounds; Thymidylate Synthase; Vitamin B 12 | 2004 |
[Folic acid fortified food and their importance in health promotion].
Topics: Coronary Disease; Dietary Supplements; Folic Acid; Food, Fortified; Humans; Neoplasms; Neural Tube Defects | 2004 |
Lighting up tumors with receptor-specific optical molecular probes.
Topics: Animals; Bombesin; Carbocyanines; Carrier Proteins; Cell Membrane; Coloring Agents; Contrast Media; Diagnostic Imaging; Disease Models, Animal; Epidermal Growth Factor; Fluorescent Dyes; Folic Acid; Humans; Light; Models, Chemical; Models, Molecular; Molecular Probes; Neoplasms; Neurotensin; Peptides; Photosensitizing Agents; Somatostatin; Xanthenes | 2004 |
Physiology of folate and vitamin B12 in health and disease.
Topics: Folic Acid; Food, Fortified; Humans; Neoplasms; Neural Tube Defects; Vitamin B 12 | 2004 |
Pharmacogenomics of thymidylate synthase in cancer treatment.
Topics: Animals; Antineoplastic Agents; Fluorouracil; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Loss of Heterozygosity; Neoplasms; Pharmacogenetics; Polymerase Chain Reaction; Polymorphism, Genetic; Promoter Regions, Genetic; Thymidylate Synthase; Treatment Outcome | 2004 |
[Role of folates in the nutrition of the elderly].
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cognition Disorders; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Food, Fortified; Health Education; Humans; Hyperhomocysteinemia; Male; Neoplasms; Nutrition Policy; Nutritional Status; Poland; Primary Prevention; Risk Factors | 2004 |
DNA methylation, cancer susceptibility, and nutrient interactions.
Topics: Animals; Choline Deficiency; Deficiency Diseases; Diet; Disease Susceptibility; DNA Methylation; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Neoplasms; Selenium | 2004 |
Will mandatory folic acid fortification prevent or promote cancer?
Topics: Animals; DNA Methylation; Folic Acid; Food, Fortified; Humans; Infant, Newborn; Neoplasms; Neural Tube Defects | 2004 |
[Does folic acid have effects on other health problems than neural tube defects?].
Topics: Cardiovascular Diseases; Female; Folic Acid; Food, Fortified; Humans; Neoplasms; Neural Tube Defects; Pregnancy | 2005 |
Micronutrients and cancer.
Topics: Antioxidants; DNA Damage; Folic Acid; Fruit; Humans; Micronutrients; Neoplasms; Oxidation-Reduction; Risk Factors; Selenium; Vegetables | 2004 |
Targeted drug delivery in cancer therapy.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carrier Proteins; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Endothelium, Vascular; Folate Receptors, GPI-Anchored; Folic Acid; Gene Transfer Techniques; Humans; Immunotherapy; Immunotoxins; Ligands; Magnetics; Mice; Nanostructures; Neoplasms; Neovascularization, Pathologic; Oleic Acid; Receptors, Cell Surface; Receptors, LDL; Recombinant Fusion Proteins; Time Factors; Trastuzumab | 2005 |
Effects of alcohol on folate metabolism: implications for carcinogenesis.
Topics: Animals; Betaine; Biological Availability; Central Nervous System Depressants; Choline; Ethanol; Folic Acid; Humans; Neoplasms | 2005 |
Pyrimidines as the cytostatic drugs.
Topics: Animals; Antineoplastic Agents; Cytosine; Drug Design; Folic Acid; Humans; Neoplasms; Pyrimidines | 1992 |
Folate receptor-mediated drug targeting: from therapeutics to diagnostics.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Carrier Proteins; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Immunotherapy; Liposomes; Nanostructures; Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Cell Surface; Toxins, Biological | 2005 |
Role of folate receptor genes in reproduction and related cancers.
Topics: Biomarkers, Tumor; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Genetic Markers; Glycosylphosphatidylinositols; Humans; Ligands; Membrane Transport Proteins; Neoplasms; Ovarian Neoplasms; Ovary; Placenta; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Glucocorticoid; Reproduction; RNA Processing, Post-Transcriptional; Transcription, Genetic | 2006 |
Interactions between folate and aging for carcinogenesis.
Topics: Aging; Animals; Carbon; DNA Methylation; Folic Acid; Humans; Neoplasms | 2005 |
Pharmacogenetics of folate-related drug targets in cancer treatment.
Topics: Animals; Antineoplastic Agents; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Models, Biological; Neoplasms; Pharmacogenetics; Polymorphism, Genetic; Thymidylate Synthase | 2005 |
Folate during antifolate chemotherapy: what we know... and do not know.
Topics: Antimetabolites, Antineoplastic; Dietary Supplements; Folic Acid; Folic Acid Antagonists; Humans; Neoplasms; Vitamin B Complex | 2005 |
Genetic and epigenetic interactions between folate and aging in carcinogenesis.
Topics: Aging; Animals; DNA Methylation; Epigenesis, Genetic; Folic Acid; Neoplasms; Rats | 2005 |
Multidrug resistance proteins and folate supplementation: therapeutic implications for antifolates and other classes of drugs in cancer treatment.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Folic Acid; Folic Acid Antagonists; Humans; Neoplasm Proteins; Neoplasms | 2006 |
5,10-Methylenetetrahydrofolate reductase polymorphisms and pharmacogenetics: a new role of single nucleotide polymorphisms in the folate metabolic pathway in human health and disease.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Arthritis, Rheumatoid; Folic Acid; Humans; Neoplasms; Pharmacogenetics; Polymorphism, Genetic; Polymorphism, Single Nucleotide | 2005 |
Cytotoxic anticancer agents and renal impairment study: the challenge remains.
Topics: Antimetabolites, Antineoplastic; Drug Administration Schedule; Folic Acid; Glomerular Filtration Rate; Glutamates; Guanine; Humans; Kidney Failure, Chronic; Neoplasms; Pemetrexed; Vitamin B 12 | 2006 |
The role of folate receptor alpha in cancer development, progression and treatment: cause, consequence or innocent bystander?
Topics: Animals; Canada; Carrier Proteins; Cytosol; Dietary Supplements; Disease Progression; DNA, Neoplasm; Folate Receptor 1; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Homocysteine; Humans; Mutation; Neoplasms; Prognosis; Receptors, Cell Surface; Transcription Factors; Tumor Cells, Cultured; United States | 2006 |
Vitamins and minerals 4: overview of folate and the B vitamins.
Topics: Alzheimer Disease; Cardiovascular Diseases; Chemoprevention; Dementia, Vascular; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Neoplasms; Primary Prevention; Risk Factors; Risk Reduction Behavior; Vitamin B 12; Vitamin B 6 | 2006 |
[Folic acid fortification: prevention as well as promotion of cancer].
Topics: Animals; Cardiovascular Diseases; Cognition Disorders; Evidence-Based Medicine; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Neoplasms; Pregnancy; Prenatal Nutritional Physiological Phenomena; Vitamin B 12 Deficiency | 2006 |
Synergy of genes and nutrients: the case of homocysteine.
Topics: Folic Acid; Food, Fortified; Homocysteine; Humans; Hyperhomocysteinemia; Mood Disorders; Neoplasms; Public Health; Selection, Genetic; Vitamin B 12 Deficiency; Vitamin B Complex | 2006 |
Pemetrexed: biochemical and cellular pharmacology, mechanisms, and clinical applications.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Clinical Trials as Topic; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Neoplasms; Pemetrexed | 2007 |
Modulation of response to cancer chemotherapeutic agents by diet constituents: is the available evidence sufficiently robust for rational advice for patients?
Topics: Animals; Anthracyclines; Antineoplastic Agents; Antioxidants; Cisplatin; Clinical Trials as Topic; Counseling; Diet; Dietary Supplements; Drug Interactions; Folic Acid; Humans; Mice; Neoplasms; Rats; Vitamin E | 2007 |
Molecular basis of antifolate resistance.
Topics: Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Antagonists; Humans; Neoplasms | 2007 |
Human reduced folate carrier: translation of basic biology to cancer etiology and therapy.
Topics: Amino Acid Sequence; Biological Transport; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Humans; Membrane Transport Proteins; Molecular Sequence Data; Neoplasms; Reduced Folate Carrier Protein | 2007 |
Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Autoimmune Diseases; Carrier Proteins; Drug Design; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Receptors, Cell Surface | 2008 |
Strategies for in vivo siRNA delivery in cancer.
Topics: Animals; Drug Delivery Systems; Folic Acid; Humans; Liposomes; Neoplasms; Polymers; RNA, Small Interfering | 2008 |
Methylenetetrahydrofolate reductase (MTHFR): a novel target for cancer therapy.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Delivery Systems; Folic Acid; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oligonucleotides, Antisense | 2008 |
The pharmacology and clinical use of methotrexate.
Topics: Administration, Oral; Animals; Biological Transport; Central Nervous System; Drug Resistance; Folic Acid; Folic Acid Antagonists; Gene Amplification; Head and Neck Neoplasms; Humans; Kinetics; Leucovorin; Leukemia, Lymphoid; Lung Neoplasms; Methotrexate; Neoplasms; Osteoma, Osteoid; Thymidylate Synthase; Tissue Distribution | 1983 |
Implications of nutritional status on human biochemistry, physiology, and health.
Topics: Alcoholism; Anemia, Hypochromic; Animals; Ascorbic Acid; Avitaminosis; Climate; Dietary Fats; Female; Folic Acid; Food Additives; Health; Humans; Immunocompetence; Lactation; Male; Neoplasms; Nutritional Physiological Phenomena; Nutritional Requirements; Obesity; Physical Exertion; Pregnancy; Protein-Energy Malnutrition; Pyridoxine; Riboflavin; Smoking; Stress, Physiological; Thiamine; Trace Elements; Vitamin A; Vitamins; Zinc | 1984 |
Dihydrofolate reductase inhibitors as potential drugs.
Topics: Aminopterin; Animals; Antimalarials; Bacterial Infections; Biological Transport; Drug Interactions; Folic Acid; Folic Acid Antagonists; Helminthiasis; Humans; Immunosuppressive Agents; Leukemia, Experimental; Liver; Methotrexate; Mice; Mycoses; Neoplasms; Protozoan Infections; Psoriasis; Quinazolines; Rats; Receptors, Drug; Trypanosoma cruzi | 1981 |
New directions in dietary studies in cancer: the National Cancer Institute.
Topics: Animals; Antioxidants; Clinical Trials as Topic; Diet; Dietary Fats; Dietary Fiber; Estrogens, Non-Steroidal; Female; Folic Acid; Health Education; Humans; Isoflavones; Male; National Institutes of Health (U.S.); Neoplasms; Phytoestrogens; Plant Preparations; Research Design; Risk Factors; United States | 1995 |
Health implications of Mediterranean diets in light of contemporary knowledge. 1. Plant foods and dairy products.
Topics: Bone and Bones; Calcium, Dietary; Coronary Disease; Dairy Products; Diet; Europe; Folic Acid; Fractures, Bone; Humans; Neoplasms; Neural Tube Defects; Plants, Edible; Risk Factors | 1995 |
New techniques in the pharmacokinetic analysis of cancer drugs. III. Nuclear magnetic resonance.
Topics: Antineoplastic Agents; Fluorouracil; Folic Acid; Humans; Magnetic Resonance Spectroscopy; Misonidazole; Neoplasms | 1993 |
Folate requirements for health in different population groups.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Coronary Disease; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Infant, Newborn; Middle Aged; Neoplasms; Neural Tube Defects; Nutritional Requirements; Nutritional Status; Pregnancy; Prenatal Care | 1995 |
Aspects of one-carbon folate cycling related to fluoropyrimidine and antifolate therapy.
Topics: Animals; Antimetabolites, Antineoplastic; Fluorodeoxyuridylate; Fluorouracil; Folic Acid; Folic Acid Antagonists; Glycine Hydroxymethyltransferase; Humans; Leucovorin; Neoplasms | 1995 |
[Folate deficiency, cancer and congenital abnormalities. Is there a connection?].
Topics: Adult; Congenital Abnormalities; DNA; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Humans; Methylation; Neoplasms; Pregnancy | 1996 |
Folate, antifolates, and folate analogs in pediatric oncology.
Topics: Antimetabolites, Antineoplastic; Child; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms | 1996 |
The role of folate, choline, and methionine in carcinogenesis induced by methyl-deficient diets.
Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Humans; Liver Neoplasms; Methionine; Neoplasms | 1996 |
Alcohol and cancer.
Topics: Animals; Carcinogens; Epidemiologic Factors; Esophageal Neoplasms; Ethanol; Folic Acid; Humans; Methylation; Mice; Murine Acquired Immunodeficiency Syndrome; Neoplasms; Vitamin E | 1994 |
Folic acid and food fortification: implications for the primary care practitioner.
Topics: Coronary Disease; Edible Grain; Female; Folic Acid; Food, Fortified; Humans; Neoplasms; Neural Tube Defects; Nurse Practitioners; Primary Health Care; Public Health; United States; United States Food and Drug Administration | 1997 |
Vitamins and cancer.
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Female; Folic Acid; Humans; Male; Neoplasms; Proto-Oncogene Mas; Selenium; Vitamin A; Vitamin E; Vitamins | 1997 |
Folate-based thymidylate synthase inhibitors in cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Enzyme Inhibitors; Folic Acid; Humans; Neoplasms; Neoplasms, Experimental; Thymidylate Synthase | 1997 |
[Oxaliplatin: the first DACH platinum in clinical practice].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Male; Neoplasms; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Peripheral Nervous System Diseases; Survival Analysis | 1997 |
Folate in preventive medicine: a new role in cardiovascular disease, neural tube defects and cancer.
Topics: Cardiovascular Diseases; Folic Acid; Humans; Neoplasms; Neural Tube Defects | 1997 |
Folate and its various ramifications.
Topics: Cerebrovascular Disorders; Congenital Abnormalities; Coronary Disease; Female; Folic Acid; Folic Acid Deficiency; Heart Defects, Congenital; Humans; Neoplasms; Neural Tube Defects; Pregnancy | 1998 |
Folate-mediated targeting of therapeutic and imaging agents to cancers.
Topics: Animals; Contrast Media; Drug Delivery Systems; Endocytosis; Folic Acid; Humans; Ligands; Neoplasms | 1998 |
Should all elderly people receive folate supplements?
Topics: Aged; Aging; Coronary Disease; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Nutritional Requirements; Nutritional Status | 1998 |
Nutrition, cancer, and aging.
Topics: Aging; Animals; Antioxidants; Calcium, Dietary; Carcinogens; Dietary Fiber; DNA Damage; Energy Intake; Folic Acid; Folic Acid Deficiency; Humans; Neoplasms; Nutritional Physiological Phenomena; Risk Factors | 1998 |
Micronutrients prevent cancer and delay aging.
Topics: Aging; Antioxidants; Diet; Folic Acid; Fruit; Humans; Iron; Neoplasms; Vegetables; Vitamins; Zinc | 1998 |
Therapeutic strategies targeting proteins that regulate folate and reduced folate transport.
Topics: Antimetabolites, Antineoplastic; Carrier Proteins; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Receptors, Cell Surface; Trimetrexate | 1999 |
Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement.
Topics: Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Neural Tube Defects; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors; Vascular Diseases | 1999 |
Folate and cancer prevention: a new medical application of folate beyond hyperhomocysteinemia and neural tube defects.
Topics: Adolescent; Adult; Alcohol Drinking; Animals; beta Carotene; Breast Neoplasms; Case-Control Studies; Female; Folic Acid; Follow-Up Studies; Hematinics; Humans; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Middle Aged; Neoplasms; Odds Ratio; Pancreatic Neoplasms; Postmenopause; Premenopause; Prospective Studies; Randomized Controlled Trials as Topic; Rats; Risk; Risk Factors; Smoking; Time Factors; Vitamins | 1999 |
The role of micronutrients in DNA synthesis and maintenance.
Topics: Animals; Ascorbic Acid; DNA; DNA Damage; DNA Repair; Folic Acid; Folic Acid Deficiency; Humans; Neoplasms; Niacin; Vitamin B 12 Deficiency; Vitamins | 1999 |
Problems and approaches in investigating the role of micronutrients in the aetiology of cancer in humans.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Arylamine N-Acetyltransferase; Colorectal Neoplasms; Folic Acid; Genetic Predisposition to Disease; Hemochromatosis; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Micronutrients; Neoplasms; Oxidoreductases; Polymorphism, Genetic; Protective Agents; Research Design | 1999 |
Maternal folate status and lactation.
Topics: Animals; Animals, Suckling; Arteriosclerosis; Disease Susceptibility; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Infant; Infant, Newborn; Iron Deficiencies; Lactation; Mammals; Milk; Neoplasms; Neural Tube Defects; Neutrophils; Nutritional Requirements; Pregnancy; Pregnancy Complications; Pteroylpolyglutamic Acids; Rats | 1997 |
[Economic evaluation in oncology].
Topics: Antineoplastic Agents; Cost-Benefit Analysis; Folic Acid; Germany; Humans; Medical Oncology; Neoplasms | 2000 |
Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk: a paradigm of gene-nutrient interactions in carcinogenesis.
Topics: DNA Methylation; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Risk Factors | 2000 |
Clinical and laboratory features and sequelae of deficiency of folic acid (folate) and vitamin B12 (cobalamin) in pregnancy and gynecology.
Topics: Anemia, Megaloblastic; Anemia, Pernicious; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Neoplasms; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Vascular Diseases; Vitamin B 12; Vitamin B 12 Deficiency | 2000 |
Liposome targeting to tumors using vitamin and growth factor receptors.
Topics: Antineoplastic Agents; Carrier Proteins; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; In Vitro Techniques; Ligands; Liposomes; Microscopy, Confocal; Neoplasms; Receptors, Cell Surface; Receptors, Growth Factor; Vitamins | 2000 |
Dietary strategies to reduce the burden of cancer and cardiovascular disease in the UK.
Topics: Adult; beta Carotene; Cardiovascular Diseases; Diet; Female; Folic Acid; Food, Fortified; Health Policy; Humans; Male; Middle Aged; Neoplasms; Obesity; Pregnancy; Randomized Controlled Trials as Topic; Socioeconomic Factors; United Kingdom; Vitamins | 2000 |
Folate-targeted non-viral DNA vectors for cancer gene therapy.
Topics: Animals; Carrier Proteins; DNA; Drug Delivery Systems; Endosomes; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Neoplasms; Receptors, Cell Surface; Tumor Cells, Cultured | 2000 |
Cellular aspects of folate and antifolate membrane transport.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Membrane; Drug Resistance; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Membrane Transport Proteins; Neoplasms; Receptors, Cell Surface; Reduced Folate Carrier Protein | 2000 |
Diet and cancer prevention.
Topics: Alcohol Drinking; Clinical Trials as Topic; Diet; Dietary Fats; Dietary Fiber; DNA, Neoplasm; Exercise; Folic Acid; Fruit; Humans; Minerals; Neoplasms; Oncogenes; Randomized Controlled Trials as Topic; RNA, Neoplasm; Vegetables; Vitamins | 2001 |
New perspectives on folate catabolism.
Topics: Animals; Biological Transport; Drug Stability; Embryonic and Fetal Development; Female; Folic Acid; Humans; Infant, Newborn; Neoplasms; Nutritional Status; Pregnancy | 2001 |
Familiar drugs may prevent cancer.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anticarcinogenic Agents; Aspirin; Celecoxib; Cyclooxygenase Inhibitors; Female; Folic Acid; Humans; Male; Neoplasms; Pyrazoles; Raloxifene Hydrochloride; Sulfonamides; Tamoxifen; Vitamin A | 2001 |
Importance of folate in human nutrition.
Topics: Biological Availability; Birth Weight; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; India; Intestinal Absorption; Liver; Male; Meat; Neoplasms; Neural Tube Defects; Nutrition Policy; Nutritional Physiological Phenomena; Pregnancy; Prevalence; Public Health; Vegetables | 2001 |
A critical assessment of some biomarker approaches linked with dietary intake.
Topics: Aflatoxins; Antioxidants; Biomarkers; Brassica; Carotenoids; Developing Countries; Diet; Environmental Exposure; Flavonoids; Folic Acid; Food Additives; Food Analysis; Food Contamination; Free Radicals; Genetic Predisposition to Disease; Humans; Intestinal Absorption; Meat; Neoplasms; Nutritional Status; Polycyclic Aromatic Hydrocarbons; Predictive Value of Tests; Reproducibility of Results; Selenium; Selenium Compounds; Sensitivity and Specificity; Vitamin A; Vitamin B 12; Vitamin B Deficiency | 2001 |
Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and requirements.
Topics: Animals; Diet; DNA; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipid Peroxidation; Neoplasms; Nutritional Status; Oxidative Stress; Tetrahydrofolate Dehydrogenase; Uracil | 2001 |
Future directions in the development of pemetrexed.
Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Dietary Supplements; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Forecasting; Glutamates; Guanine; Humans; Neoplasms; Pemetrexed; Vitamin B 12 | 2002 |
Folic acid and homocysteine in age-related disease.
Topics: Aged; Aging; Cardiovascular Diseases; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Mental Disorders; Neoplasms; Neurodegenerative Diseases; Stroke | 2002 |
Vitamins for chronic disease prevention in adults: scientific review.
Topics: Ascorbic Acid; Avitaminosis; Blood Coagulation; Breast Neoplasms; Carotenoids; Chronic Disease; Colorectal Neoplasms; Coronary Disease; Dietary Supplements; Female; Folic Acid; Fractures, Bone; Humans; Lung Neoplasms; Male; Neoplasms; Neural Tube Defects; Prostatic Neoplasms; Risk Factors; Vitamin A; Vitamin B 12; Vitamin B 6; Vitamin D; Vitamin E; Vitamin K; Vitamins | 2002 |
Molecular targets for nutrients involved with cancer prevention.
Topics: Anticarcinogenic Agents; Calcium; Diet; Folic Acid; Food Technology; Genistein; Humans; Neoplasms; Nutritional Physiological Phenomena; Polymorphism, Genetic; Resveratrol; Selenium; Stilbenes; Vitamin D | 2001 |
Pterin-6-aldehyde production from folic acid by malignant tissues.
Topics: Erythrocytes; Folic Acid; Humans; Neoplasms; Pteridines; Pterins | 1977 |
Studies with high-dose methotrexate--historical background.
Topics: Aminopterin; Animals; Folic Acid; History, 20th Century; Humans; Leucovorin; Leukemia, Experimental; Methotrexate; Mice; Neoplasms; Time Factors | 1978 |
Hormonal steroid contraceptives: a further review of adverse reactions.
Topics: Age Factors; Animals; Blood Coagulation; Cerebrovascular Disorders; Chemical and Drug Induced Liver Injury; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Coronary Disease; Folic Acid; Humans; Hypertension; Metabolism; Myocardial Infarction; Neoplasms; Progestins; Skin; Smoking; Teratogens; Thromboembolism; Time Factors; Vitamin B 12 | 1978 |
Transport of folate compounds in bacterial and mammalian cells.
Topics: Bacteria; Biological Transport, Active; Carrier Proteins; Cells; Eukaryotic Cells; Folic Acid; Kinetics; Neoplasms; Nucleotides, Cyclic; Substrate Specificity | 1978 |
Biochemical and kinetic approaches to inhibition of multiple pathways.
Topics: Animals; Antimetabolites; Biological Transport; Drug Interactions; Enzyme Inhibitors; Enzymes; Folic Acid; Kinetics; Metabolism; Neoplasms | 1979 |
[Totally implantable systems for long-term chemotherapeutic treatment].
Topics: Antineoplastic Combined Chemotherapy Protocols; Evaluation Studies as Topic; Fluorouracil; Folic Acid; Humans; Infusion Pumps, Implantable; Neoplasms; Time Factors | 1992 |
Acquired versus intrinsic resistance to methotrexate: diversity of the drug-resistant phenotype in mammalian cells.
Topics: Animals; Cricetinae; Drug Resistance; Folic Acid; Humans; Methotrexate; Mice; Neoplasms; Tetrahydrofolate Dehydrogenase | 1991 |
The renewed potential for folate antagonists in contemporary cancer chemotherapy.
Topics: Antineoplastic Agents; Folic Acid; Folic Acid Antagonists; Humans; Neoplasms; Quinazolines; Structure-Activity Relationship; Thymidylate Synthase | 1991 |
The place of chemoprevention studies in cancer prevention planning.
Topics: beta Carotene; Biomarkers; Carotenoids; Clinical Trials as Topic; Folic Acid; Health Planning; Humans; Neoplasms; Nutritional Physiological Phenomena; Vitamin A | 1990 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Clinical chemistry of folic acid.
Topics: Absorption; Aged; Alcoholism; Anemia, Sickle Cell; Anticonvulsants; Arthritis, Rheumatoid; Biological Assay; Biological Transport; Bone Marrow; Carrier Proteins; Chemical Phenomena; Chemistry; Contraceptives, Oral; Female; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Food Analysis; Formiminoglutamic Acid; Glutamate Formimidoyltransferase; Humans; Hydroxymethyl and Formyl Transferases; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infections; Kidney Failure, Chronic; Malabsorption Syndromes; Malaria; Methotrexate; Neoplasms; Nervous System Diseases; Nutritional Requirements; Parenteral Nutrition, Total; Pregnancy; Pyrimethamine; Receptors, Cell Surface; Terminology as Topic; Thalassemia; Transferases; Trimethoprim | 1986 |
A new direction in preventive oncology: chemoprevention.
Topics: Adult; Ascorbic Acid; Calcium; Clinical Trials as Topic; Drug Therapy; Education, Nursing, Continuing; Female; Folic Acid; Humans; Male; Neoplasms; Oncology Nursing; Research; Retinoids; Selenium; Tamoxifen; Vitamin A; Vitamin D; Vitamin E | 1986 |
Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: biological significance and implications for improved therapy of human cancer.
Topics: Animals; Biological Transport; Cell Division; Cell Transformation, Neoplastic; Extraembryonic Membranes; Female; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Neoplasms; Oncogenes; Pregnancy | 1985 |
Tumour growth and curability.
Topics: Animals; Antineoplastic Agents; Cell Count; Choriocarcinoma; Female; Folic Acid; Humans; Mitosis; Neoplasms; Pregnancy; Time Factors; Trophoblasts | 1970 |
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.
Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors; Enzyme Precursors; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Leukemia, Myeloid; Liver; Mercaptopurine; Methotrexate; Mice; Molecular Weight; Neoplasms; Nucleic Acids; Proteus; Purines; Research; Species Specificity; Thymine; Transferases; Uric Acid; Xanthine Oxidase | 1969 |
Empirical vs. rational approaches in cancer chemotherapy.
Topics: Animals; Enterococcus faecalis; Escherichia coli; Folic Acid; Folic Acid Antagonists; Leukemia, Experimental; Methyltransferases; Mice; Neoplasms; Thymine Nucleotides; Uracil Nucleotides | 1971 |
23 trial(s) available for folic acid and Benign Neoplasms
| Article | Year |
|---|---|
A Phase I Trial of CT900, a Novel α-Folate Receptor-Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer.
Topics: Enzyme Inhibitors; Female; Folic Acid; Humans; Maximum Tolerated Dose; Neoplasms; Ovarian Neoplasms; Thymidylate Synthase | 2022 |
Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Randomized Clinical Trial.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Asian People; Capecitabine; Chi-Square Distribution; Dihydrouracil Dehydrogenase (NADP); Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Genetic Predisposition to Disease; Genome-Wide Association Study; Hand-Foot Syndrome; Humans; Incidence; Intracellular Signaling Peptides and Proteins; Kaplan-Meier Estimate; Logistic Models; Male; Membrane Proteins; Microfilament Proteins; Middle Aged; Multivariate Analysis; Neoplasms; Odds Ratio; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Predictive Value of Tests; Pyridoxine; Risk Assessment; Risk Factors; Severity of Illness Index; Singapore; Time Factors; Treatment Outcome | 2017 |
Folic Acid and Vitamin B12 Supplementation and the Risk of Cancer: Long-term Follow-up of the B Vitamins for the Prevention of Osteoporotic Fractures (B-PROOF) Trial.
Topics: Aged; Aged, 80 and over; Colorectal Neoplasms; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Male; Neoplasms; Netherlands; Osteoporotic Fractures; Vitamin B 12 | 2019 |
A phase I pharmacokinetic and safety analysis of epothilone folate (BMS-753493), a folate receptor targeted chemotherapeutic agent in humans with advanced solid tumors.
Topics: Adult; Aged; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Epothilones; Female; Folic Acid; Half-Life; Humans; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms | 2015 |
Effect of folic acid supplementation on cancer risk among adults with hypertension in China: A randomized clinical trial.
Topics: Adult; Aged; Antihypertensive Agents; China; Dietary Supplements; Double-Blind Method; Drug Administration Schedule; Enalapril; Female; Folic Acid; Humans; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Treatment Outcome | 2017 |
Sex-Specific Associations between One-Carbon Metabolism Indices and Posttranslational Histone Modifications in Arsenic-Exposed Bangladeshi Adults.
Topics: Adult; Arsenic; Bangladesh; Carbon; Creatine; Dietary Supplements; Environmental Exposure; Female; Folic Acid; Histone Code; Humans; Incidence; Leukocytes, Mononuclear; Male; Middle Aged; Neoplasms; Protein Processing, Post-Translational; Sex Distribution; Sex Factors; Vitamin B Complex; Water Pollutants, Chemical; Young Adult | 2017 |
A phase I trial of pemetrexed plus gemcitabine given biweekly with B-vitamin support in solid tumor malignancies or advanced epithelial ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Deoxycytidine; Dietary Supplements; Drug Administration Schedule; Female; Folic Acid; Gemcitabine; Glutamates; Guanine; Humans; Maximum Tolerated Dose; Neoplasms; Neutropenia; Ovarian Neoplasms; Pemetrexed; Treatment Outcome; Vitamin B Complex | 2008 |
Effect of combined folic acid, vitamin B6, and vitamin B12 on cancer risk in women: a randomized trial.
Topics: Adult; Aged; Antioxidants; Breast Neoplasms; Cardiovascular Diseases; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Middle Aged; Neoplasms; Risk; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2008 |
Clinical pharmacokinetics and exposure-toxicity relationship of a folate-Vinca alkaloid conjugate EC145 in cancer patients.
Topics: Adult; Aged; Body Surface Area; Carrier Proteins; Constipation; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Nonlinear Dynamics; Peripheral Nervous System Diseases; Receptors, Cell Surface; Vinblastine; Vinca Alkaloids | 2009 |
B vitamin and/or ω-3 fatty acid supplementation and cancer: ancillary findings from the supplementation with folate, vitamins B6 and B12, and/or omega-3 fatty acids (SU.FOL.OM3) randomized trial.
Topics: Aged; Aged, 80 and over; Anticarcinogenic Agents; Biomarkers; Chemoprevention; Dietary Supplements; Fatty Acids, Omega-3; Female; Folic Acid; Humans; Incidence; Male; Middle Aged; Neoplasms; Odds Ratio; Proportional Hazards Models; Research Design; Risk Factors; Secondary Prevention; Sex Factors; Treatment Failure; United States; Vitamin B 12; Vitamin B 6 | 2012 |
Phase I study of folate conjugate EC145 (Vintafolide) in patients with refractory solid tumors.
Topics: Adult; Aged; Antineoplastic Agents; Constipation; Drug Administration Schedule; Drug Resistance, Neoplasm; Fatigue; Female; Folic Acid; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neoplasms; Severity of Illness Index; Vinca Alkaloids; Vomiting | 2012 |
Capecitabine treatment results in increased mean corpuscular volume of red blood cells in patients with advanced solid malignancies.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Erythrocyte Indices; Erythrocytes; Female; Fluorouracil; Folic Acid; Hematinics; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Prospective Studies; Retrospective Studies; Thymidylate Synthase; Vitamin B 12 | 2003 |
Phase I and pharmacokinetic study of pemetrexed administered every 3 weeks to advanced cancer patients with normal and impaired renal function.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Drug Administration Schedule; Fatigue; Female; Folic Acid; Glutamates; Guanine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nausea; Neoplasms; Neutropenia; Pemetrexed; Thrombocytopenia; Vitamin B 12 | 2006 |
A phase I study of pemetrexed (LY231514) supplemented with folate and vitamin B12 in Japanese patients with solid tumours.
Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Folic Acid; Glutamates; Guanine; Humans; Infusions, Intravenous; Japan; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Neutropenia; Pemetrexed; Safety; Treatment Outcome; Vitamin B 12 | 2006 |
Phase I and pharmacokinetic study of pemetrexed with high-dose folic acid supplementation or multivitamin supplementation in patients with locally advanced or metastatic cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Dietary Supplements; Female; Folic Acid; Glutamates; Guanine; Humans; Infusions, Parenteral; Male; Neoplasm Metastasis; Neoplasms; Pemetrexed; Vitamin B Complex | 2007 |
Folic acid for the prevention of colorectal adenomas: a randomized clinical trial.
Topics: Adenoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chi-Square Distribution; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Neoplasms; Risk; Treatment Failure | 2007 |
Phase I study of phosphonacetyl-L-aspartate, 5-fluorouracil, and leucovorin in patients with advanced cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Diarrhea; Digestive System; Drug Synergism; Female; Fluorouracil; Folic Acid; Humans; Leucovorin; Male; Middle Aged; Neoplasms; Neutropenia; Phosphonoacetic Acid; Proportional Hazards Models; Pyrimidines; Remission Induction; Risk Factors; Thymidylate Synthase | 1995 |
Failure of pretreatment with intravenous folic acid to alter the cumulative hematologic toxicity of lometrexol.
Topics: Antimetabolites, Antineoplastic; Drug Administration Schedule; Female; Folic Acid; Folic Acid Antagonists; Humans; Infusions, Intravenous; Male; Neoplasms; Pancytopenia; Stomatitis; Tetrahydrofolates; Treatment Failure | 1996 |
Clinical pharmacokinetics of the antipurine antifolate (6R)-5,10- dideaza-5,6,7,8-tetrahydrofolic acid (Lometrexol) administered with an oral folic acid supplement.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Area Under Curve; Blood Proteins; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasms; Tetrahydrofolates | 1995 |
Weekly lometrexol with daily oral folic acid is appropriate for phase II evaluation.
Topics: Administration, Oral; Adult; Aged; Anemia; Drug Administration Schedule; Drug Evaluation; Erythrocyte Count; Female; Folic Acid; Folic Acid Antagonists; Hematinics; Humans; Infusions, Intravenous; Lymphoma; Male; Middle Aged; Neoplasms; Tetrahydrofolates | 2000 |
A phase I and pharmacokinetic study of 1843U89, a noncompetitive inhibitor of thymidylate synthase, in patients with advanced solid malignancies.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exanthema; Female; Folic Acid; Humans; Indoles; Infusions, Intravenous; Isoindoles; Male; Middle Aged; Mouth Mucosa; Neoplasms; Neutropenia; Quinazolines; Stomatitis; Thymidylate Synthase | 2001 |
The place of chemoprevention studies in cancer prevention planning.
Topics: beta Carotene; Biomarkers; Carotenoids; Clinical Trials as Topic; Folic Acid; Health Planning; Humans; Neoplasms; Nutritional Physiological Phenomena; Vitamin A | 1990 |
A new direction in preventive oncology: chemoprevention.
Topics: Adult; Ascorbic Acid; Calcium; Clinical Trials as Topic; Drug Therapy; Education, Nursing, Continuing; Female; Folic Acid; Humans; Male; Neoplasms; Oncology Nursing; Research; Retinoids; Selenium; Tamoxifen; Vitamin A; Vitamin D; Vitamin E | 1986 |
783 other study(ies) available for folic acid and Benign Neoplasms
| Article | Year |
|---|---|
Folic acid conjugates of a bleomycin mimic for selective targeting of folate receptor positive cancer cells.
Topics: Antineoplastic Agents; Bleomycin; Folic Acid; Humans; Neoplasms | 2019 |
Selenium Vacancy Engineering Using Bi
Topics: Animals; Antineoplastic Agents; Bismuth; Cattle; Cell Line, Tumor; Contrast Media; Density Functional Theory; Female; Folic Acid; Infrared Rays; Mice, Inbred BALB C; Models, Chemical; Neoplasms; Photoacoustic Techniques; Photothermal Therapy; Quantum Dots; Selenium Compounds; Serum Albumin, Bovine | 2021 |
Effect of targeting ligand designation of self-assembly chitosan-poloxamer nanogels loaded Paclitacel on inhibiting MCF-7 cancer cell growth.
Topics: Cell Line, Tumor; Chitosan; Drug Carriers; Folic Acid; Humans; Ligands; MCF-7 Cells; Nanogels; Nanoparticles; Neoplasms; Paclitaxel; Poloxamer | 2022 |
Study of the interaction of folic acid-modified gold nanorods and fibrinogen through microfluidics: implications for protein adsorption, incorporation and viability of cancer cells.
Topics: Adsorption; Fibrinogen; Folic Acid; Gold; Metal Nanoparticles; Microfluidics; Nanotubes; Neoplasms; Polyethylene Glycols | 2021 |
Host-cell-assisted construction of a folate-engineered nanocarrier based on viral light particles for targeted cancer therapy.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Folic Acid; Neoplasms; Quantum Dots | 2021 |
Evaluation of Silver Nanoparticles Caffeic Acid Complex Compound as New Potential Therapeutic Agent against Cancer Incidence in Mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Caffeic Acids; Carcinoma, Ehrlich Tumor; Caspase 3; Caspase 8; Female; Folic Acid; Glutathione; Glutathione Peroxidase; Hep G2 Cells; Humans; Liver Neoplasms; MCF-7 Cells; Metal Nanoparticles; Mice; Nanoconjugates; Neoplasms; Silver; Superoxide Dismutase; Tumor Necrosis Factors | 2021 |
Preparation and Characterization of Docetaxel-PLGA Nanoparticles Coated with Folic Acid-chitosan Conjugate for Cancer Treatment.
Topics: Chitosan; Docetaxel; Folic Acid; Humans; Lactic Acid; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2022 |
Methionine synthase supports tumour tetrahydrofolate pools.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Methionine; Methylation; Mutation; Neoplasms; Purines; Tetrahydrofolates; Vitamin B 12 Deficiency | 2021 |
Methionine synthase is essential for cancer cell proliferation in physiological folate environments.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Methotrexate; Neoplasms; Tetrahydrofolates | 2021 |
Stimulus-responsive drug/gene delivery system based on polyethylenimine cyclodextrin nanoparticles for potential cancer therapy.
Topics: Antineoplastic Agents; Apoptosis; beta-Cyclodextrins; Cell Line, Tumor; Cell Survival; Cyclodextrins; Doxorubicin; Drug Delivery Systems; Drug Liberation; Folic Acid; Gene Transfer Techniques; Humans; MCF-7 Cells; Nanoparticles; Neoplasms; Polyethyleneimine; RNA, Small Interfering | 2022 |
Targeted drug delivery
Topics: Animals; Curcumin; Drug Carriers; Drug Delivery Systems; Folic Acid; Mice; Micelles; Neoplasms; Polyethylene Glycols; Polymers | 2022 |
Co-Delivery of Paclitaxel and shMCL-1 by Folic Acid-Modified Nonviral Vector to Overcome Cancer Chemotherapy Resistance.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Drug Carriers; Drug Resistance, Neoplasm; Folic Acid; G2 Phase Cell Cycle Checkpoints; Humans; Mice; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Nanocomposites; Neoplasms; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Signal Transduction; Transfection | 2021 |
Bioinspired synthesis of protein/polysaccharide-decorated folate as a nanocarrier of curcumin to potentiate cancer therapy.
Topics: Alginates; Animals; Chitosan; Curcumin; Folic Acid; Mice; Nanoparticles; Neoplasms | 2022 |
Biodegradable nanoparticles combining cancer cell targeting and anti-angiogenic activity for synergistic chemotherapy in epithelial cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Drug Carriers; Endothelial Cells; Folic Acid; Nanoparticles; Neoplasms; Zebrafish | 2022 |
Folic Acid-Conjugated Gold Nanostars for Computed Tomography Imaging and Photothermal/Radiation Combined Therapy.
Topics: Apoptosis; Folic Acid; Gold; HeLa Cells; Humans; Nanostructures; Neoplasms; Photochemotherapy; Reactive Oxygen Species; Tomography, X-Ray Computed | 2021 |
Zwitterionic choline phosphate conjugated folate-poly (ethylene glycol): a general decoration of erythrocyte membrane-coated nanoparticles for enhanced tumor-targeting drug delivery.
Topics: Erythrocyte Membrane; Folic Acid; Humans; Nanoparticles; Neoplasms; Phosphorylcholine; Polyethylene Glycols | 2022 |
Surface Plasmon Resonance, a Novel Technique for Sensing Cancer Biomarker: Folate Receptor and Nanoparticles Interface.
Topics: Biomarkers, Tumor; Biosensing Techniques; Folate Receptor 1; Folic Acid; Humans; Nanoparticles; Neoplasms; Surface Plasmon Resonance | 2022 |
Topics: Folic Acid; Humans; Lactic Acid; Male; MicroRNAs; Nanoparticles; Neoplasms; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spermatogonia; Stem Cells | 2022 |
An Intelligent Nanovehicle Armed with Multifunctional Navigation for Precise Delivery of Toll-Like Receptor 7/8 Agonist and Immunogenic Cell Death Amplifiers to Eliminate Solid Tumors and Trigger Durable Antitumor Immunity.
Topics: Adjuvants, Immunologic; Cell Line, Tumor; Folic Acid; Humans; Immunogenic Cell Death; Immunotherapy; Mannose; Nanoparticles; Neoplasms; Oxaliplatin; Polymers; Toll-Like Receptor 7; Tumor Microenvironment | 2022 |
Reactive Oxygen Species and Folate Receptor-Targeted Nanophotosensitizers Composed of Folic Acid-Conjugated and Poly(ethylene glycol)-Chlorin e6 Tetramer Having Diselenide Linkages for Targeted Photodynamic Treatment of Cancer Cells.
Topics: Cell Line, Tumor; Chlorophyllides; Folic Acid; Humans; Hydrogen Peroxide; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Porphyrins; Reactive Oxygen Species | 2022 |
Deacetylation of MTHFD2 by SIRT4 senses stress signal to inhibit cancer cell growth by remodeling folate metabolism.
Topics: Aminohydrolases; Cell Transformation, Neoplastic; Folic Acid; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondrial Proteins; Neoplasms; Sirtuins | 2022 |
Co-delivery of doxorubicin and CRISPR/Cas9 or RNAi-expressing plasmid by chitosan-based nanoparticle for cancer therapy.
Topics: Cell Line, Tumor; Chitosan; CRISPR-Cas Systems; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Frontotemporal Dementia; Humans; Nanoparticles; Neoplasms; Plasmids; RNA Interference; Survivin | 2022 |
Targeted delivery of doxorubicin by Thermo/pH-responsive magnetic nanoparticles in a rat model of breast cancer.
Topics: Animals; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Hydrogen-Ion Concentration; Magnetite Nanoparticles; Nanoparticles; Neoplasms; Rats | 2022 |
Hypoxia responsive and tumor-targeted mixed micelles for enhanced cancer therapy and real-time imaging.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Folic Acid; Humans; Hypoxia; Micelles; Neoplasms; Paclitaxel | 2022 |
Glucose-Responsive ZIF-8 Nanocomposites for Targeted Cancer Therapy through Combining Starvation with Stimulus-Responsive Nitric Oxide Synergistic Treatment.
Topics: Folic Acid; Glucose; Humans; Hydrogen Peroxide; Metal-Organic Frameworks; Nanocomposites; Neoplasms; Nitric Oxide; Serum Albumin, Bovine; Zeolites | 2022 |
Self-assembled Pt(II) metallacycles enable precise cancer combination chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Liberation; Drug Synergism; Folic Acid; Humans; Mice; Nanoparticles; Neoplasms; Platinum; Polymers; Stilbenes; Tumor Microenvironment | 2022 |
The potential of folic acid and homocysteine as novel serum markers for venous thromboembolism in cancer patients.
Topics: Biomarkers; Factor VIII; Folic Acid; Homocysteine; Humans; Neoplasms; Tissue Plasminogen Activator; Venous Thromboembolism | 2022 |
Prevalence of micronutrient deficiency and its impact on the outcome of childhood cancer: A prospective cohort study.
Topics: Child; Copper; Folic Acid; Hematologic Neoplasms; Humans; Longitudinal Studies; Malnutrition; Micronutrients; Neoplasms; Prevalence; Prospective Studies; Selenium; Vitamin B 12; Vitamins; Zinc | 2022 |
Folic acid conjugated PAMAM-modified mesoporous silica-coated superparamagnetic iron oxide nanoparticles for potential cancer therapy.
Topics: Drug Delivery Systems; Folic Acid; Humans; Magnetic Iron Oxide Nanoparticles; Nanoparticles; Neoplasms; Polyamines; Silicon Dioxide | 2022 |
Rod-like hybrid nanomaterial with tumor targeting and pH-responsive for cancer chemo/photothermal synergistic therapy.
Topics: Cell Line, Tumor; Cisplatin; Doxorubicin; Folic Acid; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Nanocomposites; Neoplasms; Phototherapy; Photothermal Therapy; Polyethylene Glycols | 2022 |
Nanofabrication of PLGA-PEG-chitosan-folic acid systems for delivery of colchicine to HT-29 cancer cells.
Topics: Antioxidants; Chitosan; Colchicine; Drug Carriers; Folic Acid; Humans; Nanoparticles; Neoplasms; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer | 2023 |
Ultra-Small and Metabolizable Near-Infrared Au/Gd Nanoclusters for Targeted FL/MRI Imaging and Cancer Theranostics.
Topics: Animals; Cell Line, Tumor; Contrast Media; Folic Acid; Gold; Magnetic Resonance Imaging; Metal Nanoparticles; Mice; Neoplasms; Precision Medicine; Reactive Oxygen Species | 2022 |
Copper Nanocluster Enables Simultaneous Photodynamic and Chemo Therapy for Effective Cancer Diagnosis and Treatment in Vitro.
Topics: Antineoplastic Agents; Cell Line, Tumor; Copper; Doxorubicin; Folic Acid; Glutathione; HeLa Cells; Humans; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen | 2022 |
Galactomannan armed superparamagnetic iron oxide nanoparticles as a folate receptor targeted multi-functional theranostic agent in the management of cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Folic Acid; Galactose; Humans; Magnetic Iron Oxide Nanoparticles; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mannans; Methotrexate; Mice; Nanoparticles; Neoplasms; Theranostic Nanomedicine | 2022 |
Folic Acid Enables Targeting Delivery of Lipodiscs by Circumventing IgM-Mediated Opsonization.
Topics: Cell Line, Tumor; Drug Delivery Systems; Folic Acid; Humans; Immunoglobulin M; Liposomes; Nanoparticles; Neoplasms; Opsonization | 2022 |
Chiral FA Conjugated CdTe/CdS Quantum Dots for Selective Cancer Ablation.
Topics: Cadmium Compounds; Folic Acid; Ligands; Neoplasms; Quantum Dots; Tellurium | 2022 |
Fabrication of bovine serum albumin-polyethylene glycol nanoparticle conjugated-folic acid loaded-naringenin as an efficient carrier biomacromolecule for suppression of cancer cells.
Topics: Cell Line, Tumor; Drug Carriers; Folic Acid; Nanoparticles; Neoplasms; Polyethylene Glycols; Serum Albumin, Bovine | 2023 |
Erythrocyte-Derived Nanoparticles with Folate Functionalization for Near Infrared Pulsed Laser-Mediated Photo-Chemotherapy of Tumors.
Topics: Animals; Cell Line, Tumor; Doxorubicin; Erythrocytes; Folic Acid; Hyperthermia, Induced; Indocyanine Green; Lasers; Mice; Nanoparticles; Neoplasms; Phototherapy | 2022 |
Cancer Risk in Children of Mothers With Epilepsy and High-Dose Folic Acid Use During Pregnancy.
Topics: Child; Child, Preschool; Cohort Studies; Epilepsy; Female; Folic Acid; Humans; Male; Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Risk | 2022 |
2D Copper(II) Metalated Metal-Organic Framework Nanocomplexes for Dual-enhanced Photodynamic Therapy and Amplified Antitumor Immunity.
Topics: Catalase; Cell Line, Tumor; Copper; Folic Acid; Humans; Hydrogen Peroxide; Metal Nanoparticles; Metal-Organic Frameworks; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Platinum; Reactive Oxygen Species; Tumor Microenvironment | 2022 |
Upconversion Optogenetic Engineered Bacteria System for Time-Resolved Imaging Diagnosis and Light-Controlled Cancer Therapy.
Topics: Bacteria; Folic Acid; Humans; Ligands; Nanoparticles; Neoplasms; Optogenetics; Tumor Microenvironment | 2022 |
Biology and therapeutic applications of the proton-coupled folate transporter.
Topics: Antineoplastic Agents; Biology; Folic Acid; Folic Acid Antagonists; Humans; Neoplasms; Pemetrexed; Proton-Coupled Folate Transporter | 2022 |
Design and synthesis of multi-targeted nanoparticles for gene delivery to breast cancer tissues.
Topics: Animals; DNA; Female; Folic Acid; Gene Transfer Techniques; Glucose; Heparan Sulfate Proteoglycans; Mice; Nanoparticles; Neoplasms; Polyethylene Glycols; Spermine | 2023 |
Ultrasmall Folate Receptor Alpha Targeted Enzymatically Cleavable Silica Nanoparticle Drug Conjugates Augment Penetration and Therapeutic Efficacy in Models of Cancer.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Folate Receptor 1; Folic Acid; Humans; Mice; Nanoparticle Drug Delivery System; Nanoparticles; Neoplasms; Silicon Dioxide | 2022 |
Full Remission of CAR-Deficient Tumors by DOTAP-Folate Liposome Encapsulation of Adenovirus.
Topics: Adenoviridae; Animals; Folic Acid; Humans; Liposomes; Mice; Neoplasms; Propane | 2022 |
Enhancement of Anti-Tumoral Properties of Paclitaxel Nano-Crystals by Conjugation of Folic Acid to Pluronic F127: Formulation Optimization, In Vitro and In Vivo Study.
Topics: Drug Liberation; Folic Acid; Humans; Neoplasms; Paclitaxel; Poloxamer | 2022 |
Changes in Dietary Intake of Methionine, Folate/Folic Acid and Vitamin B12 and Survival in Postmenopausal Women with Breast Cancer: A Prospective Cohort Study.
Topics: Animals; Eating; Female; Folic Acid; Methionine; Neoplasms; Postmenopause; Prospective Studies; Racemethionine; Risk Factors; Vitamin B 12 | 2022 |
Exploratory Metabolomics Underscores the Folate Enzyme ALDH1L1 as a Regulator of Glycine and Methylation Reactions.
Topics: Aldehyde Dehydrogenase 1 Family; Folic Acid; Glycine; Humans; Metabolomics; Methylation; Neoplasms; Retinal Dehydrogenase; S-Adenosylmethionine | 2022 |
Tumor Targeting and pH-Sensitive Inclusion Complex Based on HP-β-CD as a Potential Carrier for Paclitaxel: Fabrication, Molecular Docking, and Characterization.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Drug Carriers; Excipients; Folic Acid; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Neoplasms; Paclitaxel | 2023 |
In Vitro and In Vivo Evaluation of Targeted Fluorescent Imaging Agents for Diagnosis and Resection of Cancer.
Topics: Animals; Biomarkers, Tumor; Fluorescent Dyes; Folic Acid; Male; Mice; Neoplasms; Tissue Distribution | 2022 |
Risk factors of childhood cancer in Armenia: a case-control study.
Topics: Adolescent; Armenia; Case-Control Studies; Child; Female; Folic Acid; Humans; Neoplasms; Pregnancy; Risk Factors | 2023 |
Folylpolyglutamate synthetase mRNA G-quadruplexes regulate its cell protrusion localization and enhance a cancer cell invasive phenotype upon folate repletion.
Topics: 3' Untranslated Regions; Actins; Folic Acid; G-Quadruplexes; Humans; Neoplasms | 2023 |
Folic acid-modified biocompatible Pullulan/poly(acrylic acid) nanogels for targeted delivery to MCF-7 cancer cells.
Topics: Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Nanogels; Nanoparticles; Neoplasms | 2023 |
Surface Modification of Liposomes Using Folic Acid.
Topics: Cell Line, Tumor; Drug Delivery Systems; Folic Acid; Humans; Liposomes; Neoplasms | 2023 |
Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
Topics: Adult; Cardiovascular Diseases; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Prospective Studies; Republic of Korea; Risk Factors | 2023 |
Design of novel polyurethane-based ionene nanocarriers for cancer therapy: Synthesis, in-vitro, and in-vivo studies.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Fluorouracil; Folic Acid; Mice; Nanoparticles; Neoplasms; Polyurethanes | 2023 |
Active Hydrophilic Graphene Oxide Nanocomposites Delivery Mediated by Adipose-Derived Stem Cell for Elevated Photothermal Therapy of Breast Cancer.
Topics: Adipocytes; Animals; Folic Acid; Graphite; Mice; Nanocomposites; Neoplasms; Photothermal Therapy; Polyethylene Glycols | 2023 |
Organic disulfide-modified folate carbon dots for tumor-targeted synergistic chemodynamic/photodynamic therapy.
Topics: Carbon; Cell Line, Tumor; Disulfides; Folic Acid; Glutathione; Humans; Hydrogen Peroxide; Nanoparticles; Neoplasms; Pentetic Acid; Photochemotherapy; Reactive Oxygen Species; Tumor Microenvironment | 2023 |
Design, characterization and evaluation of a new
Topics: Carrier Proteins; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Radiopharmaceuticals; Technetium | 2023 |
Prevalence of vitamin and iron deficiencies at cancer diagnosis at two pediatric oncology units in South Africa.
Topics: Child; Child, Preschool; Female; Folic Acid; Humans; Iron Deficiencies; Male; Micronutrients; Neoplasms; Nutritional Status; Prevalence; South Africa; Vitamin D; Vitamins | 2023 |
Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.
Topics: Folic Acid; Formates; Methylenetetrahydrofolate Dehydrogenase (NADP); Neoplasms; Purines; Tetrahydrofolates | 2023 |
RTP4, a Biomarker Associated with Diagnosing Pulmonary Tuberculosis and Pan-Cancer Analysis.
Topics: Biomarkers; Folic Acid; Gene Expression Profiling; Gene Regulatory Networks; Humans; Neoplasms; Reproducibility of Results; Tuberculosis, Pulmonary | 2023 |
Lawsone encapsulated polylactic-co-glycolic acid nanoparticles modified with chitosan-folic acid successfully inhibited cell growth and triggered apoptosis in Panc-1 cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Chitosan; Drug Carriers; Folic Acid; Glycols; Lactic Acid; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2023 |
Daily folate consumption is associated with reduced all-cause and cardiovascular disease mortality among US adults with diabetes, prediabetes, or insulin resistance.
Topics: Adult; Cardiovascular Diseases; Diabetes Mellitus; Folic Acid; Humans; Insulin Resistance; Neoplasms; Nutrition Surveys; Prediabetic State; Prospective Studies; Risk Factors | 2023 |
Unjustified allegation on cancer risks in children of mothers with epilepsy taking high-dose folic acid during pregnancy-No proof of a causal relationship.
Topics: Anticonvulsants; Child; Dietary Supplements; Epilepsy; Female; Folic Acid; Humans; Mothers; Neoplasms; Pregnancy; Pregnancy Complications | 2023 |
Adsorption of folic acid molecule on diphenylalanine peptide nanohole as a drug delivery in cancer treatment: a molecular dynamics simulation study.
Topics: Adsorption; Folic Acid; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Neoplasms; Peptides; Phenylalanine; Water | 2023 |
Study on Contrast-Enhanced Ultrasound Imaging and Anti-Tumor Effects of Drug-Loaded Nanodroplets with Tumor Targeting and Ultrasound Sensitivity.
Topics: Cell Line, Tumor; Folic Acid; Humans; Nanoparticles; Neoplasms; Phase Transition; Polyethylene Glycols; Polymers; Ultrasonography | 2023 |
A General Protocol for Synthesizing Thiolated Folate Derivatives.
Topics: Cell Line, Tumor; Drug Delivery Systems; Folic Acid; Humans; Metal Nanoparticles; Nanoparticles; Neoplasms; Silver | 2023 |
High-dose folic acid and cancer risk; unjustified concerns by von Wrede and colleagues regarding our paper.
Topics: Child; Dietary Supplements; Family; Female; Folic Acid; Humans; Neoplasms; Pregnancy; Risk | 2023 |
Analysis of folate and curcumin-conjugated cadmium sulfide cystein quantum dots for targeted cancer therapy.
Topics: Animals; Curcumin; Folic Acid; Mice; Neoplasms; Quantum Dots | 2023 |
Facile preparation of silver based radiosensitizers via biomineralization method for enhanced in vivo breast cancer radiotherapy.
Topics: Animals; Biomineralization; Folic Acid; Mice; Neoplasms; Radiation Oncology; Radiation-Sensitizing Agents; Research Design; Silver | 2023 |
Insights on the molecular mechanisms of cytotoxicity induced by AS1411 linked to folate-functionalized DNA nanocages in cancer cells.
Topics: Antineoplastic Agents; Aptamers, Nucleotide; Cell Line, Tumor; DNA; Folic Acid; HeLa Cells; Humans; Neoplasms; Oligodeoxyribonucleotides | 2023 |
Caffeine-folic acid-loaded-chitosan nanoparticles combined with methotrexate as a novel HepG2 immunotherapy targeting adenosine A2A receptor downstream cascade.
Topics: Adenosine; Caffeine; Chitosan; Folic Acid; Humans; Immunotherapy; Methotrexate; Molecular Docking Simulation; Nanoparticles; Neoplasms; Receptor, Adenosine A2A; Tumor Microenvironment | 2023 |
Discovery of novel tumor-targeted near-infrared probes with 6-substituted pyrrolo[2,3-d]pyrimidines as targeting ligands.
Topics: Animals; Cell Line, Tumor; Fluorescent Dyes; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; Ligands; Mice; Neoplasms; Pyrimidines | 2023 |
Selective reprogramming of regulatory T cells in solid tumors can strongly enhance or inhibit tumor growth.
Topics: Animals; Folic Acid; Humans; Immunosuppressive Agents; Mice; Molecular Docking Simulation; Neoplasms; T-Lymphocytes, Regulatory; Transcription Factors | 2023 |
Sequentially Site-Specific Delivery of Apoptotic Protein and Tumor-Suppressor Gene for Combination Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Cytochromes c; DNA; Female; Fluorescence; Folic Acid; Genes, Tumor Suppressor; Humans; Liposomes; Male; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Nanocapsules; Neoplasms; Optical Imaging; Particle Size; Protamines; Rats, Sprague-Dawley; Static Electricity; Tissue Distribution; Tumor Suppressor Protein p53 | 2019 |
Folate-displaying exosome mediated cytosolic delivery of siRNA avoiding endosome trapping.
Topics: Animals; Cell Line, Tumor; Cytosol; Endosomes; Exosomes; Female; Folic Acid; Gene Transfer Techniques; Humans; Mice, Nude; Neoplasms; RNA, Small Interfering | 2019 |
Association of transcriptional levels of folate-mediated one-carbon metabolism-related genes in cancer cell lines with drug treatment response.
Topics: Antineoplastic Agents; Carbon; Cell Line, Tumor; Folic Acid; Gene Expression Profiling; Humans; Neoplasms; Transcription, Genetic | 2019 |
New approaches to tumor therapy with siRNA-decorated and chitosan-modified PLGA nanoparticles.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cancer Pain; Cell Line, Tumor; Cell Survival; Chitosan; Cyclooxygenase Inhibitors; Drug Carriers; Flurbiprofen; Folic Acid; Humans; Mice; Nanoparticles; Neoplasms; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering; STAT3 Transcription Factor | 2019 |
Folic acid-modified ginsenoside Rg5-loaded bovine serum albumin nanoparticles for targeted cancer therapy in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Survival; Drug Carriers; Drug Liberation; Folic Acid; Ginsenosides; Humans; Hydrodynamics; Inhibitory Concentration 50; MCF-7 Cells; Mice; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Particle Size; Serum Albumin, Bovine; Tissue Distribution | 2019 |
A Dual-Model Imaging Theragnostic System Based on Mesoporous Silica Nanoparticles for Enhanced Cancer Phototherapy.
Topics: Animals; Female; Fluorocarbons; Folic Acid; Humans; Hyperthermia, Induced; Indocyanine Green; Indoles; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Nanoparticles; Neoplasms; Photochemotherapy; Phototherapy; Polyethylene Glycols; Polymers; Reactive Oxygen Species; Silicon Dioxide; Temperature; Theranostic Nanomedicine | 2019 |
Graphene oxide arms oncolytic measles virus for improved effectiveness of cancer therapy.
Topics: A549 Cells; Animals; Folic Acid; Graphite; HeLa Cells; Humans; Male; Measles virus; Mice; Mice, Nude; Nanoparticles; Neoplasms; Oncolytic Virotherapy; Polyethylene Glycols; Xenograft Model Antitumor Assays | 2019 |
A blood cell repelling and tumor cell capturing surface for high-purity enrichment of circulating tumor cells.
Topics: Blood Cells; Cell Adhesion; Cell Separation; Cell Survival; Folic Acid; HeLa Cells; Humans; Liquid Biopsy; MCF-7 Cells; Microfluidic Analytical Techniques; Neoplasms; Neoplastic Cells, Circulating; Oligopeptides; Polyethylene Glycols | 2019 |
pH-Sensitive Magnetite Nanoparticles Modified with Hyperbranched Polymers and Folic Acid for Targeted Imaging and Therapy.
Topics: Antineoplastic Agents; Cell Line, Tumor; Dendrimers; Drug Carriers; Drug Delivery Systems; Drug Liberation; Folic Acid; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; Magnetite Nanoparticles; Neoplasms; Polyethylene Glycols; Quercetin | 2019 |
Nanoassembly and Multiscale Computation of Multifunctional Optical-Magnetic Nanoprobes for Tumor-Targeted Theranostics.
Topics: Animals; Cell Line, Tumor; Folic Acid; Gadolinium; Gold; Humans; Infrared Rays; Magnetic Resonance Imaging; Magnetics; Mice; Mice, Nude; Nanotubes; Neoplasms; Photosensitizing Agents; Phototherapy; Polyethylene Glycols; Porosity; Reactive Oxygen Species; Silicon Dioxide; Theranostic Nanomedicine | 2019 |
A versatile endosome acidity-induced sheddable gene delivery system: increased tumor targeting and enhanced transfection efficiency.
Topics: Animals; Cell Death; Cell Line, Tumor; Chitosan; DNA; Endocytosis; Endosomes; Female; Folic Acid; Genetic Therapy; Green Fluorescent Proteins; Humans; Hydrogen-Ion Concentration; Mice, Inbred BALB C; Neoplasms; Nuclear Localization Signals; Particle Size; Plasmids; Polyethylene Glycols; Polyethyleneimine; Static Electricity; Transfection | 2019 |
Reprogramming the T cell response to cancer by simultaneous, nanoparticle-mediated PD-L1 inhibition and immunogenic cell death.
Topics: Animals; Antibiotics, Antineoplastic; B7-H1 Antigen; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; Immunogenic Cell Death; Mice, Inbred C57BL; MicroRNAs; Nanoparticles; Neoplasms; Polyesters; Polyethylene Glycols; T-Lymphocytes; Tumor Microenvironment | 2019 |
Low density lipoprotein mimic nanoparticles composed of amphipathic hybrid peptides and lipids for tumor-targeted delivery of paclitaxel.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apolipoprotein B-100; Biomimetic Materials; Colloids; Drug Delivery Systems; Drug Liberation; Endocytosis; Folic Acid; HeLa Cells; Humans; Lipids; Lipoproteins, LDL; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Paclitaxel; Particle Size; Peptides; Polyethylene Glycols; Static Electricity | 2019 |
Folic acid-conjugated chitosan-functionalized graphene oxide for highly efficient photoacoustic imaging-guided tumor-targeted photothermal therapy.
Topics: Animals; Cell Line, Tumor; Chitosan; Female; Folic Acid; Graphite; Humans; Mice, Inbred BALB C; Mice, Nude; Nanostructures; Neoplasms; Photoacoustic Techniques; Photothermal Therapy; Theranostic Nanomedicine | 2020 |
Ultrabright fluorescent silica nanoparticles for in vivo targeting of xenografted human tumors and cancer cells in zebrafish.
Topics: Animals; Female; Folic Acid; HeLa Cells; Humans; Nanoparticles; Neoplasms; Optical Imaging; Particle Size; Polyethylene Glycols; Porosity; Silicon Dioxide; Transplantation, Heterologous; Zebrafish | 2019 |
Polydopamine-PEG-Folic Acid Conjugate Film Engineered TiO
Topics: Biomarkers, Tumor; Biosensing Techniques; Folic Acid; Fructose-Bisphosphatase; Humans; Indoles; Nanotubes; Neoplasms; Photochemical Processes; Polyethylene Glycols; Polymers; Titanium | 2020 |
A microfluidic platform culturing two cell lines paralleled under in-vivo like fluidic microenvironment for testing the tumor targeting of nanoparticles.
Topics: A549 Cells; Animals; Apoptosis; Cell Proliferation; Chitosan; Cholesterol; Folic Acid; HeLa Cells; Humans; Mice; Mice, Nude; Microfluidics; Nanoparticles; Neoplasms; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2020 |
Topics: Animals; Cell Line, Tumor; Contrast Media; Cyclodextrins; Doxorubicin; Drug Delivery Systems; Folic Acid; Gadolinium; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Polyesters; Precision Medicine; Theranostic Nanomedicine | 2020 |
Development of surface functionalized hydroxyapatite nanoparticles for enhanced specificity towards tumor cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Drug Delivery Systems; Durapatite; Folic Acid; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; KB Cells; Mice; Nanoparticles; Neoplasms | 2020 |
Phthalocyanine-loaded nanostructured lipid carriers functionalized with folic acid for photodynamic therapy.
Topics: Drug Carriers; Folic Acid; Humans; Indoles; Isoindoles; Lipids; MCF-7 Cells; Nanostructures; Neoplasms; Photochemotherapy; Poloxamer | 2020 |
A MSN-based tumor-targeted nanoplatform to interfere with lactate metabolism to induce tumor cell acidosis for tumor suppression and anti-metastasis.
Topics: Antineoplastic Agents; Cell Line, Tumor; Fluvastatin; Folic Acid; Humans; Lactates; Manganese Compounds; Metformin; Nanoparticles; Neoplasm Metastasis; Neoplasms; Porosity; Silicon; Tumor Microenvironment | 2020 |
A tumor-targeted, intracellular activatable and theranostic nanodiamond drug platform for strongly enhanced in vivo antitumor therapy.
Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Drug Liberation; Endocytosis; Folic Acid; Humans; Hydrogen-Ion Concentration; Male; Mice; Mice, Nude; Microscopy, Confocal; Nanodiamonds; Neoplasms; Polyethylene Glycols; Theranostic Nanomedicine; Xenograft Model Antitumor Assays | 2020 |
Development of a nanodrug-delivery system camouflaged by erythrocyte membranes for the chemo/phototherapy of cancer.
Topics: Animals; Drug Delivery Systems; Erythrocyte Membrane; Folic Acid; Hyperthermia, Induced; Mice; Mice, Nude; Nanoparticles; Neoplasms; Phototherapy | 2020 |
Formulation of a pH-sensitive cancer cell-targeted gene delivery system based on folate-chitosan conjugated nanoparticles.
Topics: Chitosan; DNA; Folic Acid; Gene Transfer Techniques; Humans; Hydrogen-Ion Concentration; Nanoparticles; Neoplasms | 2021 |
Synthesis of folic acid conjugated photoluminescent carbon quantum dots with ultrahigh quantum yield for targeted cancer cell fluorescence imaging.
Topics: Carbon; Folic Acid; Humans; Neoplasms; Optical Imaging; Photochemotherapy; Photosensitizing Agents; Quantum Dots | 2020 |
Prevalence, etiology and risk factors of anemia in patients with newly diagnosed cancer.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Case-Control Studies; Cross-Sectional Studies; Female; Ferritins; Folic Acid; Folic Acid Deficiency; Humans; Iron; Male; Middle Aged; Neoplasms; Prevalence; Risk Factors; Turkey; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2020 |
Peroxidase activities of gold nanowires synthesized by TMV as template and their application in detection of cancer cells.
Topics: Animals; Biosensing Techniques; Cells; Folic Acid; Gold; HEK293 Cells; HeLa Cells; Humans; Kinetics; Mice; Nanowires; Neoplasms; NIH 3T3 Cells; Oxidation-Reduction; Peroxidases; Tobacco Mosaic Virus | 2020 |
In reply to "inpatient folate testing at an academic cancer center: single-year experience".
Topics: Folic Acid; Humans; Inpatients; Neoplasms | 2020 |
Zwitterionic shielded polymeric prodrug with folate-targeting and pH responsiveness for drug delivery.
Topics: Doxorubicin; Drug Delivery Systems; Drug Liberation; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Materials Testing; Methacrylates; Nanoparticles; Neoplasms; Phosphorylcholine; Polyethylene Glycols; Polymers; Prodrugs | 2019 |
Integration of a porous coordination network and black phosphorus nanosheets for improved photodynamic therapy of tumor.
Topics: Animals; Benzoquinones; Cell Line, Tumor; Drug Delivery Systems; Folic Acid; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Metal-Organic Frameworks; Mice; Nanostructures; Neoplasms; Phosphorus; Photochemotherapy; Porosity; Porphyrins; Reactive Oxygen Species; Xenograft Model Antitumor Assays; Zirconium | 2020 |
Study on the optical and biological properties in vitro of IR808-PEG-FA.
Topics: A549 Cells; Cell Survival; Fluorescent Dyes; Folic Acid; Humans; MCF-7 Cells; Neoplasms; Optical Imaging; Photochemotherapy; Polyethylene Glycols | 2020 |
Optimising FRET-efficiency of Nd
Topics: Animals; Cell Line, Tumor; Fluorescence Resonance Energy Transfer; Folic Acid; Humans; Infrared Rays; Luminescence; Metal Nanoparticles; Metals, Rare Earth; Mice; Nanocomposites; Neodymium; Neoplasms; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen | 2020 |
Biomineralized nanosilica-based organelles endow living yeast cells with non-inherent biological functions.
Topics: Animals; Antineoplastic Agents; Artificial Cells; Biomimetics; Biomineralization; Cell Engineering; Doxorubicin; Drug Carriers; Folic Acid; Hep G2 Cells; Humans; Mice, Inbred BALB C; Nanostructures; Neoplasms; Organelles; Saccharomyces cerevisiae; Silicon Dioxide; Xenograft Model Antitumor Assays | 2020 |
Design and Characterization of a Cancer-Targeted Drug Co-Delivery System Composed of Liposomes and Selenium Nanoparticles.
Topics: Chitosan; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Folic Acid; HeLa Cells; Humans; Liposomes; Nanoparticles; Neoplasms; Renal Dialysis; Selenium; Spectroscopy, Fourier Transform Infrared | 2020 |
Optically controlled hybrid metamaterial of plasmonic spiky gold inbuilt graphene sheets for bimodal imaging guided multimodal therapy.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Chitosan; Doxorubicin; Folic Acid; Gold; Graphite; Humans; Mice; Nanostructures; Neoplasms; Photochemotherapy; Photosensitizing Agents; Phototherapy; Protoporphyrins; Spectrum Analysis, Raman | 2020 |
Lipoprotein-Inspired Nanocarrier Composed of Folic Acid-Modified Protein and Lipids: Preparation and Evaluation of Tumor-Targeting Effect.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Drug Carriers; Drug Liberation; Endocytosis; Erythrocytes; Folic Acid; Hemolysis; Humans; Lipoproteins; Mice; Nanoparticles; Neoplasms; Paclitaxel; Particle Size; Rabbits; Serum Albumin, Bovine; Static Electricity | 2020 |
Pharmacokinetic Properties of
Topics: A549 Cells; Acetates; Animals; Folic Acid; Folic Acid Transporters; Gallium Radioisotopes; HCT116 Cells; HeLa Cells; Heterocyclic Compounds, 1-Ring; Humans; KB Cells; Kidney; Mice; Neoplasms; Positron-Emission Tomography; Putrescine; Radiopharmaceuticals; Rats; Rats, Wistar; Tissue Distribution; Xenograft Model Antitumor Assays | 2020 |
Folate-appended cyclodextrin improves the intratumoral accumulation of existing boron compounds.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Cyclodextrins; Folic Acid; Humans; Mice; Mice, Inbred BALB C; Neoplasms | 2020 |
Vitamin B12 and folic acid alleviate symptoms of nutritional deficiency by antagonizing aryl hydrocarbon receptor.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Carbazoles; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Gene Expression; Humans; Male; Malnutrition; Mice; Mice, Inbred C57BL; Neoplasms; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Vitamin B 12; Vitamin B 12 Deficiency | 2020 |
Water-Soluble
Topics: A549 Cells; Boron Compounds; Boron Neutron Capture Therapy; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Nanoconjugates; Neoplasms; Protein Binding | 2020 |
Dual-pH Sensitive Charge-Reversal Drug Delivery System for Highly Precise and Penetrative Chemotherapy.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Carbon; Doxorubicin; Drug Compounding; Female; Folic Acid; Folic Acid Transporters; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Lipids; Liposomes; Mice, Inbred BALB C; Neoplasms; Quantum Dots; Surface Properties; Tumor Burden | 2020 |
Targeted bioimaging and sensing of folate receptor-positive cancer cells using folic acid-conjugated sulfur-doped graphene quantum dots.
Topics: Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; Free Radical Scavengers; Graphite; Humans; MCF-7 Cells; Neoplasms; Quantum Dots; Sulfur | 2020 |
Fe
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Membrane Permeability; Click Chemistry; Combined Modality Therapy; Diagnostic Imaging; Doxorubicin; Drug Carriers; Drug Liberation; Ethylenes; Ferrosoferric Oxide; Folic Acid; Humans; Hyperthermia, Induced; Indicators and Reagents; Magnetite Nanoparticles; Neoplasms; Porosity; Silicon Dioxide; Siloxanes; Sulfhydryl Compounds; Surface Properties | 2020 |
One-pot synthesis of folic acid modified carbonized polymer dots with red emittision for selective imaging of cancer cells.
Topics: Carbon; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Microscopy, Confocal; Neoplasms; Optical Imaging; Polymers; Quantum Dots | 2020 |
Preparation and Evaluation of Doxorubicin-Loaded PLA-PEG-FA Copolymer Containing Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for Cancer Treatment: Combination Therapy with Hyperthermia and Chemotherapy.
Topics: Animals; Apoptosis; Doxorubicin; Drug Liberation; Endocytosis; Folic Acid; HeLa Cells; Humans; Hyperthermia, Induced; Magnetite Nanoparticles; Mice; Neoplasms; Particle Size; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared; Static Electricity | 2020 |
Enhanced antitumor effect via amplified oxidative stress by near-infrared light-responsive and folate-targeted nanoplatform.
Topics: A549 Cells; Antineoplastic Agents; Cisplatin; Drug Delivery Systems; Ferrous Compounds; Folic Acid; Humans; Hydrogen Peroxide; Indocyanine Green; MCF-7 Cells; Metallocenes; Nanoparticles; Neoplasms; Oxidative Stress; Reactive Oxygen Species | 2021 |
Folate-Targeted Transgenic Activity of Dendrimer Functionalized Selenium Nanoparticles In Vitro.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Dendrimers; DNA; Folic Acid; Folic Acid Antagonists; Gene Transfer Techniques; Humans; Metal Nanoparticles; Neoplasms; Selenium | 2020 |
Functionalized Fluorescent Silica Nanoparticles for Bioimaging of Cancer Cells.
Topics: Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Nanoparticles; Neoplasms; Rhodamines; Silicon Dioxide | 2020 |
A novel strategy for tumor therapy: targeted, PAA-functionalized nano-hydroxyapatite nanomedicine.
Topics: Acrylic Resins; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Durapatite; Folic Acid; Humans; Nanomedicine; Nanoparticles; Neoplasms | 2020 |
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Docetaxel; Endosomes; Female; Fibrinolytic Agents; Folate Receptor 1; Folic Acid; Heparin; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Micelles; Nanoparticles; Neoplasms; Patents as Topic | 2020 |
In Silico Prediction of Metabolic Fluxes in Cancer Cells with Altered S-adenosylmethionine Decarboxylase Activity.
Topics: Adenosine Triphosphate; Adenosylmethionine Decarboxylase; Antineoplastic Agents; Computer Simulation; Epigenesis, Genetic; Folic Acid; Glutathione; Humans; Methionine; Models, Biological; Neoplasms; Phenotype; Polyamines; Serine; Taurine; Uric Acid | 2021 |
Promising potential of [
Topics: Animals; Cell Line, Tumor; Folic Acid; Immunotherapy; Lutetium; Mice; Neoplasms; Radioisotopes; Radiopharmaceuticals | 2021 |
Multifunctional Hf/Mn-TCPP Metal-Organic Framework Nanoparticles for Triple-Modality Imaging-Guided PTT/RT Synergistic Cancer Therapy.
Topics: Animals; Contrast Media; Fluorescence; Folic Acid; Hafnium; HeLa Cells; Humans; Hyperthermia, Induced; Magnetic Resonance Imaging; Metal-Organic Frameworks; Metalloporphyrins; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Photoacoustic Techniques; Phototherapy; Radiotherapy, Image-Guided | 2020 |
Detection of membrane receptors on per tumor cell by nonimmobilized cell capillary electrophoresis and a mathematic model.
Topics: Electrophoresis, Capillary; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Models, Theoretical; Neoplasms; Receptors, Cell Surface | 2021 |
Nondestructive capture, release, and detection of circulating tumor cells with cystamine-mediated folic acid decorated magnetic nanospheres.
Topics: Cell Separation; Cystamine; Folic Acid; HEK293 Cells; HeLa Cells; Humans; Magnets; Nanospheres; Neoplasms; Neoplastic Cells, Circulating | 2020 |
Synthesis, In Silico Prediction and In Vitro Evaluation of Antitumor Activities of Novel Pyrido[2,3-
Topics: A549 Cells; Antineoplastic Agents; Binding Sites; Chemistry Techniques, Synthetic; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Folic Acid; Humans; Inhibitory Concentration 50; Janus Kinase 2; MCF-7 Cells; Molecular Docking Simulation; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Pteridines; Pyridines; Pyrimidines; Tetrahydrofolate Dehydrogenase; Tumor Suppressor Protein p53; Xanthine | 2020 |
Folic Acid-Modified Erythrocyte Membrane Loading Dual Drug for Targeted and Chemo-Photothermal Synergistic Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Combined Modality Therapy; Doxorubicin; Drug Delivery Systems; Drug Liberation; Erythrocyte Membrane; Folic Acid; Hep G2 Cells; Humans; Hyperthermia, Induced; Indocyanine Green; Mice; Nanoparticles; Neoplasms; Phototherapy; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2021 |
Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability.
Topics: Animals; Carbon Cycle; Cell Line; CRISPR-Cas Systems; Cytosol; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Male; Mice; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Mitochondria; Neoplasms; Reduced Folate Carrier Protein | 2021 |
Efficient Synthesis of Folate-Conjugated Hollow Polymeric Capsules for Accurate Drug Delivery to Cancer Cells.
Topics: Capsules; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Neoplasms; Polymers | 2021 |
Mediating the Fate of Cancer Cell Uptake: Dual-Targeted Magnetic Nanovectors with Biotin and Folate Surface Ligands.
Topics: Biotin; Folic Acid; Humans; Ligands; Magnetic Phenomena; Magnetics; Neoplasms | 2020 |
Design and synthesis of highly fluorescent and stable fullerene nanoparticles as probes for folic acid detection and targeted cancer cell imaging.
Topics: Animals; Chlorocebus aethiops; COS Cells; Drug Stability; Fluorescent Dyes; Folic Acid; Fullerenes; HeLa Cells; Humans; Microscopy, Fluorescence; Neoplasms; Particle Size | 2021 |
Construction of Surface-Modified Polydopamine Nanoparticles for Sequential Drug Release and Combined Chemo-Photothermal Cancer Therapy.
Topics: Animals; Doxorubicin; Drug Liberation; Folic Acid; Hep G2 Cells; Humans; Hyperthermia, Induced; Indoles; Infrared Rays; Male; Mice; Nanoparticles; Neoplasms; Particle Size; Phototherapy; Photothermal Therapy; Polyethylene Glycols; Polymers; Rats; Rats, Sprague-Dawley | 2021 |
Folate transporter dynamics and therapy with classic and tumor-targeted antifolates.
Topics: Biological Transport; Cell Proliferation; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; HeLa Cells; Humans; Methotrexate; Neoplasms; Ornithine; Pemetrexed; Proton-Coupled Folate Transporter; Pterins; Reduced Folate Carrier Protein | 2021 |
Polymeric Encapsulation of a Ru(II)-Based Photosensitizer for Folate-Targeted Photodynamic Therapy of Drug Resistant Cancers.
Topics: Cell Culture Techniques; Cell Line; Cell Survival; Coordination Complexes; Drug Resistance, Neoplasm; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Light; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polymers; Ruthenium; Singlet Oxygen; Spheroids, Cellular | 2021 |
Au Catalyzing Control Release NO in vivo and Tumor Growth-Inhibiting Effect in Chemo-Photothermal Combination Therapy.
Topics: Catalysis; Cell Death; Cell Proliferation; Doxorubicin; Drug Liberation; Endocytosis; Folic Acid; Gold; Humans; Magnetic Phenomena; MCF-7 Cells; Nanoparticles; Neoplasms; Nitric Oxide; Particle Size; Photothermal Therapy; Porosity; Silicon; X-Ray Diffraction | 2021 |
Defect-engineered porphyrinic metal-organic framework nanoparticles for targeted multimodal cancer phototheranostics.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Folic Acid; Humans; Indoles; Metal-Organic Frameworks; Mice; Nanoparticles; Neoplasms; Neoplasms, Experimental; Optical Imaging; Photochemotherapy; Photosensitizing Agents; Porphyrins; Propionates; Reactive Oxygen Species; Theranostic Nanomedicine | 2021 |
A promising dual-drug targeted delivery system in cancer therapy: nanocomplexes of folate-apoferritin-conjugated cationic solid lipid nanoparticles.
Topics: Antineoplastic Agents; Apoferritins; Cations; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Delivery Systems; Folic Acid; Humans; Liposomes; MCF-7 Cells; Nanoparticles; Neoplasms | 2021 |
Cancer Selective Target Degradation by Folate-Caged PROTACs.
Topics: Antineoplastic Agents; Enzyme Inhibitors; Folic Acid; Humans; Ligands; Molecular Structure; Neoplasms; Proteolysis; Pyrrolidines; Thiazoles; Ubiquitin-Protein Ligases | 2021 |
Identification and elimination of cancer cells by folate-conjugated CdTe/CdS Quantum Dots Chiral Nano-Sensors.
Topics: Apoptosis; Breast Neoplasms; Cadmium Compounds; Cell Line, Tumor; Circular Dichroism; Female; Folic Acid; Humans; Neoplasms; Quantum Dots; Sulfides; Tellurium | 2021 |
A multiple environment-sensitive prodrug nanomicelle strategy based on chitosan graftomer for enhanced tumor therapy of gambogic acid.
Topics: Acrylic Resins; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chitosan; Drug Carriers; Drug Liberation; Folic Acid; Humans; Hydrogen-Ion Concentration; Male; Mice; Micelles; Neoplasms; Prodrugs; Temperature; Xanthones | 2021 |
Red-light-responsive coordination polymers nanorods: New strategy for ultrasensitive photothermal detection of targeted cancer cells.
Topics: Biosensing Techniques; Folic Acid; Nanotubes; Neoplasms; Platinum; Polymers | 2021 |
Functionalization of Photosensitized Silica Nanoparticles for Advanced Photodynamic Therapy of Cancer.
Topics: Drug Screening Assays, Antitumor; Folic Acid; HeLa Cells; Humans; Nanoparticles; Neoplasms; Photochemotherapy; Polyethylene Glycols; Rose Bengal; Silicon Dioxide | 2021 |
A Novel Folic Acid Receptor-Targeted Drug Delivery System Based on Curcumin-Loaded β-Cyclodextrin Nanoparticles for Cancer Treatment.
Topics: Animals; Antineoplastic Agents; beta-Cyclodextrins; Curcumin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Female; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Particle Size; Polyesters; Tissue Distribution; Xenograft Model Antitumor Assays | 2021 |
Fluorescent detection of microRNA-21 in MCF-7 cells based on multifunctional gold nanorods and the integration of chemotherapy and phototherapy.
Topics: Biomarkers, Tumor; Cell Line, Tumor; DNA; Doxorubicin; Drug Carriers; Drug Liberation; Drug Therapy; Fluorescent Dyes; Folic Acid; Gold; Humans; Immobilized Nucleic Acids; Infrared Rays; MicroRNAs; Nanocomposites; Nanotubes; Neoplasms; Photothermal Therapy | 2021 |
Amplification of oxidative stress with lycorine and gold-based nanocomposites for synergistic cascade cancer therapy.
Topics: Amaryllidaceae Alkaloids; Animals; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum Stress; Folic Acid; Gold; Humans; Mice; Microscopy, Fluorescence; Mitochondria; Nanocomposites; Neoplasms; Osteosarcoma; Oxidative Stress; Phenanthridines; Reactive Oxygen Species; Silicon Dioxide | 2021 |
A nanocellulose-based platform towards targeted chemo-photodynamic/photothermal cancer therapy.
Topics: Antineoplastic Agents; Carbon; Cell Survival; Cellulose; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Folic Acid; HeLa Cells; Humans; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Photothermal Therapy; Reactive Oxygen Species | 2021 |
Self-Reported Dietary Supplement Use Is Reproducible and Relatively Valid in the Cancer Prevention Study-3 Diet Assessment Substudy.
Topics: Calcium; Diet; Diet Records; Diet Surveys; Dietary Supplements; Female; Fish Oils; Folic Acid; Humans; Male; Neoplasms; Prospective Studies; Reproducibility of Results; Self Report; Surveys and Questionnaires; Vitamin D | 2022 |
Combinatorial delivery of superparamagnetic iron oxide nanoparticles (γFe
Topics: Animals; Doxorubicin; Drug Carriers; Ferric Compounds; Folic Acid; HeLa Cells; Humans; Hyperthermia, Induced; Mice; Nanoparticles; Neoplasms | 2017 |
Role of generation on folic acid-modified poly(amidoamine) dendrimers for targeted delivery of baicalin to cancer cells.
Topics: A549 Cells; Dendrimers; Drug Delivery Systems; Flavonoids; Folic Acid; HeLa Cells; Humans; Neoplasms; Polyamines | 2017 |
pH-sensitive Au-BSA-DOX-FA nanocomposites for combined CT imaging and targeted drug delivery.
Topics: Animals; Cell Line; Contrast Media; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Folate Receptors, GPI-Anchored; Folic Acid; Gold; Humans; Hydrogen-Ion Concentration; Male; Mice, Inbred BALB C; Nanocomposites; Nanoparticles; Neoplasms; Serum Albumin, Bovine; Tomography, X-Ray Computed; Xenograft Model Antitumor Assays | 2017 |
Targeted delivery of Bcl-2 conversion gene by MPEG-PCL-PEI-FA cationic copolymer to combat therapeutic resistant cancer.
Topics: Drug Resistance, Neoplasm; Folic Acid; Humans; Micelles; Neoplasms; Polyesters; Polyethylene Glycols; Polyethyleneimine; Proto-Oncogene Proteins c-bcl-2 | 2017 |
Folate receptor-targeted ultrasonic PFOB nanoparticles: Synthesis, characterization and application in tumor-targeted imaging.
Topics: Animals; Cell Line, Tumor; Contrast Media; Fluorocarbons; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Hydrocarbons, Brominated; Liposomes; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Optical Imaging; Polyethylene Glycols; Ultrasonography | 2017 |
pH-Sensitive Delivery Vehicle Based on Folic Acid-Conjugated Polydopamine-Modified Mesoporous Silica Nanoparticles for Targeted Cancer Therapy.
Topics: Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Hydrogen-Ion Concentration; Indoles; Nanoparticles; Neoplasms; Polymers; Silicon Dioxide | 2017 |
Folic Acid-Targeted Etoposide Cubosomes for Theranostic Application of Cancer Cell Imaging and Therapy.
Topics: Animals; Calorimetry, Differential Scanning; Cell Death; Cell Survival; Diagnostic Imaging; Drug Delivery Systems; Drug Liberation; Etoposide; Folic Acid; Humans; Inhibitory Concentration 50; Liquid Crystals; MCF-7 Cells; Mice; Neoplasms; Particle Size; Proton Magnetic Resonance Spectroscopy; Static Electricity; Theranostic Nanomedicine | 2017 |
Enhancing Photodynamic Therapy through Resonance Energy Transfer Constructed Near-Infrared Photosensitized Nanoparticles.
Topics: Animals; Boron Compounds; Cell Line, Tumor; Cell Survival; Energy Transfer; Folic Acid; Humans; Infrared Rays; Mice; Micelles; Microscopy, Confocal; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Poloxamer; Polymers; Transplantation, Heterologous | 2017 |
Five-nanometer ZnSn
Topics: Animals; Folic Acid; Human Umbilical Vein Endothelial Cells; Humans; Luminescent Agents; Male; MCF-7 Cells; Metal Nanoparticles; Mice; Muscle, Skeletal; Neoplasms; Swine; Tin; Zinc | 2017 |
Synthesis of folate‑chitosan nanoparticles loaded with ligustrazine to target folate receptor positive cancer cells.
Topics: A549 Cells; Chitosan; Drug Liberation; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Nanoparticles; Neoplasms; Proton Magnetic Resonance Spectroscopy; Pyrazines; Spectrophotometry, Infrared; Time Factors | 2017 |
Folate and Heptamethine Cyanine Modified Chitosan-Based Nanotheranostics for Tumor Targeted Near-Infrared Fluorescence Imaging and Photodynamic Therapy.
Topics: Carbocyanines; Chitosan; Drug Delivery Systems; Fluorescence; Folic Acid; HeLa Cells; Hep G2 Cells; Humans; Infrared Rays; Nanoparticles; Neoplasms; Photochemotherapy; Theranostic Nanomedicine | 2017 |
Folic acid conjugated nanoliposomes as promising carriers for targeted delivery of bleomycin.
Topics: Bleomycin; Folic Acid; HeLa Cells; Humans; Liposomes; MCF-7 Cells; Nanoparticles; Neoplasms | 2018 |
Emergence of Gold-Mesoporous Silica Hybrid Nanotheranostics: Dox-Encoded, Folate Targeted Chemotherapy with Modulation of SERS Fingerprinting for Apoptosis Toward Tumor Eradication.
Topics: 3T3-L1 Cells; A549 Cells; Animals; Apoptosis; Cell Line, Tumor; Cells, Cultured; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Gold; HeLa Cells; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanostructures; Neoplasms; Peptide Mapping; Remission Induction; Silicon Dioxide; Spectrum Analysis, Raman; Theranostic Nanomedicine; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells.
Topics: Drug Carriers; Endocytosis; Folic Acid; Gold; Humans; Hydrogen-Ion Concentration; KB Cells; MCF-7 Cells; Metal Nanoparticles; Neoplasms; Polyethylene Glycols; Proof of Concept Study | 2017 |
Bubble-generating nano-lipid carriers for ultrasound/CT imaging-guided efficient tumor therapy.
Topics: Bicarbonates; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Fever; Folic Acid; Gold; Hot Temperature; Humans; Lipids; Liposomes; MCF-7 Cells; Nanoparticles; Nanotubes; Neoplasms; Tomography, X-Ray Computed; Tumor Microenvironment; Ultrasonography | 2017 |
Size of single-wall carbon nanotube affects the folate receptor-mediated cancer cell targeting.
Topics: Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Flow Cytometry; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Microscopy, Fluorescence; Nanotubes, Carbon; Neoplasms; Particle Size | 2018 |
pH-sensitive and folic acid-targeted MPEG-PHIS/FA-PEG-VE mixed micelles for the delivery of PTX-VE and their antitumor activity.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents, Phytogenic; Drug Carriers; Drug Liberation; Dynamic Light Scattering; Female; Folic Acid; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Mice; Micelles; Microscopy, Electron, Transmission; Neoplasms; Paclitaxel; Particle Size; Polyethylene Glycols; Xenograft Model Antitumor Assays | 2017 |
Clickable and imageable multiblock polymer micelles with magnetically guided and PEG-switched targeting and release property for precise tumor theranosis.
Topics: Animals; Click Chemistry; Drug Delivery Systems; Endocytosis; Female; Folic Acid; HeLa Cells; Humans; Magnetic Resonance Imaging; Mice, Nude; Micelles; Neoplasms; Particle Size; Polyethylene Glycols; Polymers; Polyurethanes; Theranostic Nanomedicine | 2017 |
pH-sensitive metal-phenolic network capsules for targeted photodynamic therapy against cancer cells.
Topics: A549 Cells; Capsules; Folic Acid; HeLa Cells; Hematoporphyrins; Humans; Hydrogen-Ion Concentration; Neoplasms; Phenols; Photochemotherapy; Polyethylene Glycols | 2018 |
Click-Functionalized SERS Nanoprobes with Improved Labeling Efficiency and Capability for Cancer Cell Imaging.
Topics: Folic Acid; Gold; Humans; Metal Nanoparticles; Nanostructures; Neoplasms; Spectrum Analysis, Raman | 2017 |
A novel high drug loading mussel-inspired polydopamine hybrid nanoparticle as a pH-sensitive vehicle for drug delivery.
Topics: Animals; Antibiotics, Antineoplastic; Bivalvia; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Delivery Systems; Drug Liberation; Drug Stability; Female; Folic Acid; Hydrogen-Ion Concentration; Indoles; Mice, Inbred BALB C; Nanoparticles; Nanotubes; Neoplasms; Polymers; Silicon Dioxide; Tumor Burden | 2017 |
Rational engineering of semiconductor QDs enabling remarkable
Topics: Animals; Cell Survival; Female; Folic Acid; HCT116 Cells; HEK293 Cells; Humans; KB Cells; Light; Male; Mice, Inbred BALB C; Neoplasms; Optical Imaging; Particle Size; Photochemotherapy; Photosensitizing Agents; Polymers; Porphyrins; Quantum Dots; Semiconductors; Singlet Oxygen; Theranostic Nanomedicine; Tissue Distribution; Zinc | 2017 |
Lipid-Coated Gold Nanoparticles Functionalized by Folic Acid as Gene Vectors for Targeted Gene Delivery in vitro and in vivo.
Topics: A549 Cells; Animals; Cell Survival; Folic Acid; Genetic Vectors; Gold; Humans; MCF-7 Cells; Metal Nanoparticles; Mice; Microscopy, Confocal; Neoplasms; Phosphatidylethanolamines; Rhodamines; Spectrophotometry, Ultraviolet; Transfection | 2017 |
Facile Preparation of Doxorubicin-Loaded and Folic Acid-Conjugated Carbon Nanotubes@Poly(N-vinyl pyrrole) for Targeted Synergistic Chemo-Photothermal Cancer Treatment.
Topics: Antibiotics, Antineoplastic; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Hyperthermia, Induced; Nanotubes, Carbon; Neoplasms; Phototherapy; Polyvinyls; Pyrroles | 2017 |
Folic acid conjugated PEG coated gold-iron oxide core-shell nanocomplex as a potential agent for targeted photothermal therapy of cancer.
Topics: Ferric Compounds; Folic Acid; Gold; Humans; Hyperthermia, Induced; MCF-7 Cells; Nanoconjugates; Neoplasms; Phototherapy; Polyethylene Glycols | 2018 |
Vitamin Status and the Development of Postoperative Cognitive Decline in Elderly Surgical Oncologic Patients.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cognitive Dysfunction; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Neoplasms; Preoperative Period; Vitamin B 12 | 2018 |
Cross-linked magnetic nanoparticles with a biocompatible amide bond for cancer-targeted dual optical/magnetic resonance imaging.
Topics: A549 Cells; Amides; Animals; Biocompatible Materials; Carbocyanines; Folic Acid; HeLa Cells; Humans; Magnetic Resonance Imaging; Magnetics; Mice; Nanoparticles; Neoplasms; Optical Imaging; Polymers; Tissue Distribution; Transplantation, Heterologous | 2018 |
Folic acid modified Pluronic F127 coating Ag
Topics: A549 Cells; Cell Death; Cell Line, Tumor; Dynamic Light Scattering; Folic Acid; HeLa Cells; Humans; Neoplasms; Oils; Particle Size; Photoacoustic Techniques; Photoelectron Spectroscopy; Poloxamer; Quantum Dots; Silver Compounds; Solubility; Spectrophotometry, Ultraviolet; Static Electricity | 2018 |
The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD.
Topics: Aminohydrolases; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Proteins; Biofilms; Biological Products; Cell Line, Tumor; Crystallography, X-Ray; Enzyme Assays; Folic Acid; Formate-Tetrahydrofolate Ligase; Humans; Inhibitory Concentration 50; Macrolides; Methylenetetrahydrofolate Dehydrogenase (NADP); Microbial Sensitivity Tests; Minor Histocompatibility Antigens; Mitochondria; Multienzyme Complexes; Multifunctional Enzymes; Myxococcales; Neoplasms; Protein Binding | 2017 |
Targeted delivery of nucleic acids into xenograft tumors mediated by novel folate-equipped liposomes.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Down-Regulation; Female; Folic Acid; Folic Acid Transporters; HEK293 Cells; Heterografts; Humans; Kidney; Liposomes; Mice; Mice, SCID; Neoplasms; Nucleic Acids; Particle Size; Phosphatidylethanolamines; Transfection | 2018 |
Multimodal molecular 3D imaging for the tumoral volumetric distribution assessment of folate-based biosensors.
Topics: Administration, Intravenous; Algorithms; Animals; Biosensing Techniques; Calibration; Folic Acid; Imaging, Three-Dimensional; Mice, Nude; Molecular Imaging; Neoplasms; Tissue Distribution; Tumor Burden | 2018 |
Evaluation of the effects of antiepileptic drugs on folic acid uptake by human placental choriocarcinoma cells.
Topics: Adult; Anticonvulsants; Cell Line, Tumor; Cell Survival; Choriocarcinoma; Female; Folate Receptor 1; Folic Acid; Humans; Neoplasms; Placenta Diseases; Pregnancy; Proton-Coupled Folate Transporter; Valproic Acid | 2018 |
Multi-Functional Peptide-MicroRNA Nanocomplex for Targeted MicroRNA Delivery and Function Imaging.
Topics: Animals; Antagomirs; Apoptosis; Caspase 3; Drug Carriers; Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Mice; Mice, Nude; MicroRNAs; Microscopy, Confocal; Nanostructures; Neoplasms; Optical Imaging; Peptides; Transfection; Transplantation, Heterologous; Up-Regulation | 2018 |
The benefits of folic acid-modified gold nanoparticles in CT-based molecular imaging: radiation dose reduction and image contrast enhancement.
Topics: Cell Line, Tumor; Contrast Media; Folic Acid; Gold; Humans; Metal Nanoparticles; Molecular Imaging; Neoplasms; Tomography, X-Ray Computed | 2018 |
Folic acid-modified liposomal drug delivery strategy for tumor targeting of 5-fluorouracil.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Fluorouracil; Folic Acid; Liposomes; Male; Mice; Mice, Inbred BALB C; Neoplasms; Rats; Rats, Wistar | 2018 |
Absence of Albumin Improves in Vitro Cellular Uptake and Disruption of Poloxamer 407-Based Nanoparticles inside Cancer Cells.
Topics: Albumins; Antineoplastic Agents; Drug Carriers; Drug Development; Fibroblasts; Folic Acid; HeLa Cells; Humans; Nanoparticles; Neoplasms; Poloxamer; Polyethylene Glycols | 2018 |
Calcium carbonate end-capped, folate-mediated Fe
Topics: A549 Cells; Antibiotics, Antineoplastic; Calcium Carbonate; Daunorubicin; Delayed-Action Preparations; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Magnetite Nanoparticles; Neoplasms; Silicon Dioxide | 2018 |
Biodegradable Drug-Loaded Hydroxyapatite Nanotherapeutic Agent for Targeted Drug Release in Tumors.
Topics: Animals; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Durapatite; Folic Acid; Mice; Neoplasms | 2018 |
Redox-responsive F127-folate/F127-disulfide bond-d-α-tocopheryl polyethylene glycol 1000 succinate/P123 mixed micelles loaded with paclitaxel for the reversal of multidrug resistance in tumors.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Disulfides; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Folic Acid; Humans; Inhibitory Concentration 50; MCF-7 Cells; Micelles; Mitochondria; Neoplasms; Oxidation-Reduction; Paclitaxel; Poloxalene; Poloxamer; Reactive Oxygen Species; Vitamin E | 2018 |
[THE DIFFERENTIATED APPROACH TO PREVENTION OF NEURAL TUBE DEFECTS IN CHILDREN].
Topics: Adult; Dietary Supplements; Drinking Water; Family Characteristics; Female; Fever; Folic Acid; Gene Expression; Genetic Counseling; Humans; Hyperhomocysteinemia; Infant, Newborn; Methylenetetrahydrofolate Reductase (NADPH2); Myocardial Infarction; Neoplasms; Neural Tube Defects; Polymorphism, Single Nucleotide; Pregnancy; Retrospective Studies; Risk Factors; Stroke; Thrombosis; Tobacco Smoke Pollution; Ukraine; Water Pollution | 2018 |
Development of a functionalized UV-emitting nanocomposite for the treatment of cancer using indirect photodynamic therapy.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Folic Acid; Luminescent Agents; Male; Mice; Nanocomposites; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Prostatic Neoplasms; Protoporphyrins; Reactive Oxygen Species; Silicon Dioxide; Yttrium | 2018 |
Understanding the Effects of Nanocapsular Mechanical Property on Passive and Active Tumor Targeting.
Topics: Animals; Cell Line, Tumor; Drug Delivery Systems; Elastic Modulus; Folic Acid; Humans; MCF-7 Cells; Mice, Inbred BALB C; Nanocapsules; Neoplasms; Peptides; Polyethylene Glycols; Silicon Dioxide; Surface Properties | 2018 |
Folate and cancer: a tale of Dr. Jekyll and Mr. Hyde?
Topics: Folic Acid; Humans; Neoplasms | 2018 |
Folate Deficiency Facilitates Genomic Integration of Human Papillomavirus Type 16 DNA In Vivo in a Novel Mouse Model for Rapid Oncogenic Transformation of Human Keratinocytes.
Topics: Animals; Carcinogenesis; Disease Models, Animal; DNA; Female; Folic Acid; Folic Acid Deficiency; Genome; Human papillomavirus 16; Humans; Keratinocytes; Mice, Nude; Neoplasms; Nutritional Status; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Repressor Proteins; Uterine Cervical Neoplasms; Virus Integration | 2018 |
Size and surface controllable metal-organic frameworks (MOFs) for fluorescence imaging and cancer therapy.
Topics: Antineoplastic Agents; Drug Liberation; Folic Acid; Hep G2 Cells; Humans; Metal-Organic Frameworks; Neoplasms; Particle Size; Tissue Distribution | 2018 |
Demonstration of the lack of cytotoxicity of unmodified and folic acid modified graphene oxide quantum dots, and their application to fluorescence lifetime imaging of HaCaT cells.
Topics: Cell Line, Tumor; Folate Receptors, GPI-Anchored; Folic Acid; Graphite; Humans; Microscopy, Fluorescence, Multiphoton; Neoplasms; Optical Imaging; Quantum Dots | 2018 |
Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment.
Topics: Antibodies; Carbon; Circular Dichroism; Cloning, Molecular; Folic Acid; gamma-Glutamyl Hydrolase; Humans; Hydrolysis; Immune System; Mass Spectrometry; Methotrexate; Neoplasms; Prodrugs; Pseudomonas; Recombinant Proteins; Stenotrophomonas; Zinc | 2018 |
Folate-Conjugated and Dual Stimuli-Responsive Mixed Micelles Loading Indocyanine Green for Photothermal and Photodynamic Therapy.
Topics: Drug Carriers; Folic Acid; HeLa Cells; Humans; Hyperthermia, Induced; Indocyanine Green; Micelles; Neoplasms; Photochemotherapy | 2018 |
Folic acid-cysteamine modified gold nanoparticle as a nanoprobe for targeted computed tomography imaging of cancer cells.
Topics: Biocompatible Materials; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Contrast Media; Cysteamine; Folic Acid; Gold; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Neoplasms; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Tomography, X-Ray Computed | 2018 |
Decoration of a Poly(methyl vinyl ether-co-maleic anhydride)-Shelled Selol Nanocapsule with Folic Acid Increases Its Activity Against Different Cancer Cell Lines
Topics: Animals; Cell Line, Tumor; Folic Acid; HeLa Cells; Humans; Maleates; Mice; Nanocapsules; Neoplasms; Polyethylenes; Selenium Compounds | 2018 |
Redox-Responsive Supramolecular Micelles for Targeted Imaging and Drug Delivery to Tumor.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Micelles; Neoplasms; Oxidation-Reduction | 2018 |
Construction of a multifunctional nanoprobe for tumor-targeted time-gated luminescence and magnetic resonance imaging in vitro and in vivo.
Topics: Animals; Female; Folic Acid; Luminescence; Magnetic Resonance Imaging; Mice; Mice, Nude; Nanoparticles; Neoplasms; Neoplasms, Experimental; RAW 264.7 Cells | 2018 |
Pre-clinical evaluation of EC1456, a folate-tubulysin anti-cancer therapeutic.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Cell Line, Tumor; Cisplatin; Docetaxel; Drug Evaluation, Preclinical; Folic Acid; Humans; Mice, Nude; Neoplasms; Oligopeptides; Paclitaxel; Pipecolic Acids; Topotecan; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Quantitative Assessment of Nanoparticle Biodistribution by Fluorescence Imaging, Revisited.
Topics: Animals; Carbocyanines; Drug Carriers; Female; Fluorescent Dyes; Folic Acid; Mice; Mice, Nude; Nanoparticles; Neoplasms; Optical Imaging; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution; Whole Body Imaging | 2018 |
Nucleoside Analogue-Based Supramolecular Nanodrugs Driven by Molecular Recognition for Synergistic Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Clofarabine; Folic Acid; Folic Acid Antagonists; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Mice, Inbred BALB C; Mice, Nude; Molecular Dynamics Simulation; Nanoparticles; Neoplasms; Quinazolines; Rats; Thiophenes | 2018 |
Doxorubicin and anti-VEGF siRNA co-delivery via nano-graphene oxide for enhanced cancer therapy in vitro and in vivo.
Topics: Animals; Apoptosis; Cell Proliferation; Doxorubicin; Drug Delivery Systems; Drug Liberation; Folic Acid; Gene Silencing; Graphite; HeLa Cells; Humans; Mice, Inbred ICR; Nanoparticles; Neoplasms; Polylysine; Ribonuclease, Pancreatic; RNA, Messenger; RNA, Small Interfering; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Static Electricity; Tumor Burden; Vascular Endothelial Growth Factor A | 2018 |
Targeted and Sustained Corelease of Chemotherapeutics and Gene by Injectable Supramolecular Hydrogel for Drug-Resistant Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Cations; Cell Line, Tumor; Delayed-Action Preparations; Drug Resistance, Neoplasm; Folic Acid; Gene Transfer Techniques; Humans; Hydrogels; Injections; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Polyesters; Polyethylene Glycols; Polyethyleneimine; Surface-Active Agents | 2019 |
Methotrexate-based amphiphilic prodrug nanoaggregates for co-administration of multiple therapeutics and synergistic cancer therapy.
Topics: A549 Cells; Animals; Antineoplastic Agents; Biological Availability; Camptothecin; Disulfides; Doxorubicin; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Liberation; Drug Synergism; Female; Folic Acid; Folic Acid Transporters; HeLa Cells; Humans; Hydrazones; Lysosomes; MCF-7 Cells; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Nanostructures; Neoplasm Transplantation; Neoplasms; Prodrugs | 2018 |
Prospective investigation of folic acid supplements before and during early pregnancy and paediatric and adult cancers in the Chinese children and families cohort: a pilot study in a sample of rural and urban families.
Topics: Adolescent; Adult; Child; China; Cohort Studies; Dietary Supplements; Feasibility Studies; Female; Folic Acid; Humans; Incidence; Male; Neoplasms; Neural Tube Defects; Pilot Projects; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Rural Population; Urban Population; Vitamin B Complex; Young Adult | 2018 |
Low-power and low-drug-dose photodynamic chemotherapy via the breakdown of tumor-targeted micelles by reactive oxygen species.
Topics: Animals; Antineoplastic Agents, Phytogenic; Delayed-Action Preparations; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Paclitaxel; Photochemotherapy; Polyethylene Glycols; Porphyrins; Reactive Oxygen Species | 2018 |
Folate-modified carboxymethyl-chitosan/polyethylenimine/bovine serum albumin based complexes for tumor site-specific drug delivery.
Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Survival; Chitosan; Drug Delivery Systems; Drug Liberation; Folic Acid; Humans; Male; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Polyethyleneimine; Serum Albumin, Bovine; TNF-Related Apoptosis-Inducing Ligand; Tumor Burden; Xanthones | 2018 |
New Onset Diabetes After Transplant: Data from the Folic Acid for Vascular Outcome Reduction in Transplantation Trial.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Folic Acid; Humans; Kidney Transplantation; Neoplasms | 2018 |
Synthesis and biological evaluation of redox/NIR dual stimulus-responsive polymeric nanoparticles for targeted delivery of cisplatin.
Topics: Cisplatin; Drug Delivery Systems; Drug Screening Assays, Antitumor; Folic Acid; Humans; Infrared Rays; MCF-7 Cells; Nanoparticles; Neoplasms; Oxidation-Reduction; Peptides, Cyclic | 2018 |
Folate-receptor-targeted laser-activable poly(lactide-
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Drug Liberation; Endocytosis; Female; Folate Receptors, GPI-Anchored; Folic Acid; Human Umbilical Vein Endothelial Cells; Humans; Hyperthermia, Induced; Indocyanine Green; Lactic Acid; Lasers; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Paclitaxel; Photoacoustic Techniques; Phototherapy; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Theranostic Nanomedicine; Tissue Distribution; Ultrasonography | 2018 |
Arrowtail RNA for Ligand Display on Ginger Exosome-like Nanovesicles to Systemic Deliver siRNA for Cancer Suppression.
Topics: Animals; Cell Line, Tumor; Drug Carriers; Exosomes; Folic Acid; HEK293 Cells; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasms; RNA, Small Interfering; Survivin; Xenograft Model Antitumor Assays; Zingiber officinale | 2018 |
Evaluation of Novel Tumor-Targeted Near-Infrared Probe for Fluorescence-Guided Surgery of Cancer.
Topics: A549 Cells; Animals; Drug Design; Fluorescence; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Infrared Rays; KB Cells; Mice; Molecular Docking Simulation; Neoplasms; Protein Conformation; Surgery, Computer-Assisted | 2018 |
Folate receptor-targeted liposomal nanocomplex for effective synergistic photothermal-chemotherapy of breast cancer in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Combined Modality Therapy; Doxorubicin; Drug Compounding; Drug Liberation; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gold; Hydrogen-Ion Concentration; Infrared Rays; Injections, Subcutaneous; Liposomes; Low-Level Light Therapy; Mammary Glands, Animal; Mice; Molecular Targeted Therapy; Nanotubes; Neoplasms; Protein Binding | 2019 |
Polymer Self-Assembled BMSCs with Cancer Tropism and Programmed Homing.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Survival; Folic Acid; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Nude; Neoplasms; Oleic Acid; Optical Imaging; Polymers; Rats; Rats, Sprague-Dawley; Rhodamines | 2018 |
Stacking of doxorubicin on folic acid-targeted multiwalled carbon nanotubes for in vivo chemotherapy of tumors.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Drug Compounding; Drug Delivery Systems; Folic Acid; Humans; Hydrogen-Ion Concentration; Mice; Nanotubes, Carbon; Neoplasms; Solubility; Tissue Distribution | 2018 |
Effect of the Folate Ligand Density on the Targeting Property of Folated-Conjugated Polymeric Nanoparticles.
Topics: Cell Line, Tumor; Delayed-Action Preparations; Drug Carriers; Folic Acid; Humans; Nanoparticles; Neoplasms; Paclitaxel; Polyesters | 2019 |
Preparation and characterization of folic acid functionalized bioactive glass for targeted delivery and sustained release of methotrexate.
Topics: Antineoplastic Agents; Biocompatible Materials; Cell Survival; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Folic Acid; Glass; HeLa Cells; Humans; Methotrexate; Neoplasms | 2019 |
Multiplexed In Vivo Imaging Using Size-Controlled Quantum Dots in the Second Near-Infrared Window.
Topics: Animals; Cadmium Compounds; Cell Line, Tumor; Cell Survival; Female; Folic Acid; Humans; Lead; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Neoplasms; Polymers; Quantum Dots; Spectroscopy, Near-Infrared; Sulfides; Transplantation, Heterologous | 2018 |
Label Free Ultrasmall Fluoromagnetic Ferrite-clusters for Targeted Cancer Imaging and Drug Delivery.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Ferric Compounds; Fluorescence; Folic Acid; Humans; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Manganese Compounds; Methotrexate; Mice; Nanoparticles; Neoplasms; Serum Albumin, Bovine | 2019 |
Predictors of serum cobalamin and its association with homocysteine in community-dwelling older adults.
Topics: Age Factors; Aged; Body Composition; Cross-Sectional Studies; Diet; Female; Folic Acid; Homocysteine; Humans; Independent Living; Inflammatory Bowel Diseases; Male; Neoplasms; Sex Factors; Vitamin B 12 | 2019 |
Targeted polyethylenimine/(p53 plasmid) nanocomplexes for potential antitumor applications.
Topics: Cell Survival; Drug Carriers; Fluorescein-5-isothiocyanate; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Therapy; Genetic Vectors; HeLa Cells; Hep G2 Cells; Humans; Nanoconjugates; Neoplasms; Particle Size; Plasmids; Polyethyleneimine; Tumor Suppressor Protein p53 | 2019 |
A smart tumor microenvironment responsive nanoplatform based on upconversion nanoparticles for efficient multimodal imaging guided therapy.
Topics: Animals; Biocompatible Materials; Cell Survival; Chitosan; Doxorubicin; Drug Carriers; Female; Folic Acid; HeLa Cells; Hemolysis; Humans; Infrared Rays; Mice; Microscopy, Confocal; Nanoparticles; Neoplasms; Porosity; Silicon Dioxide; Tomography, X-Ray Computed; Tungsten Compounds | 2019 |
Folate-conjugated, mesoporous silica functionalized boron nitride nanospheres for targeted delivery of doxorubicin.
Topics: Boron Compounds; Doxorubicin; Drug Delivery Systems; Female; Folic Acid; HeLa Cells; Humans; MCF-7 Cells; Nanospheres; Neoplasms; Porosity; Silicon Dioxide | 2019 |
Folic acid receptor-targeted human serum albumin nanoparticle formulation of cabazitaxel for tumor therapy.
Topics: A549 Cells; Animals; Cell Death; Cell Line, Tumor; Drug Delivery Systems; Drug Liberation; Endocytosis; Female; Folate Receptor 2; Folic Acid; HeLa Cells; Hemolysis; Humans; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Serum Albumin, Human; Taxoids; Tissue Distribution; Xenograft Model Antitumor Assays | 2019 |
Dual-targeting nanoparticles with core-crosslinked and pH/redox-bioresponsive properties for enhanced intracellular drug delivery.
Topics: Antibiotics, Antineoplastic; Apoptosis; Delayed-Action Preparations; Doxorubicin; Drug Delivery Systems; Drug Liberation; Folic Acid; Galactose; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Nanoparticles; Neoplasms; Oxidation-Reduction; Polymers | 2019 |
Folate-Targeted Polyethylene Glycol-Modified Photosensitizers for Photodynamic Therapy.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chlorophyll; Drug Carriers; Female; Folic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Injections, Intravenous; Mice; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Solubility; Tissue Distribution; Toxicity Tests, Acute; Xenograft Model Antitumor Assays | 2019 |
Engineering multifunctional bioactive citric acid-based nanovectors for intrinsical targeted tumor imaging and specific siRNA gene delivery in vitro/in vivo.
Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Cell Line, Tumor; Citric Acid; Diagnostic Imaging; Fluorescence; Folic Acid; Gene Silencing; Gene Transfer Techniques; Humans; Luminescent Measurements; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Nanotechnology; Neoplasms; Polyethyleneimine; Proton Magnetic Resonance Spectroscopy; Rats; Rhodamines; RNA, Small Interfering | 2019 |
Development of biosurfactant-based graphene quantum dot conjugate as a novel and fluorescent theranostic tool for cancer.
Topics: Cell Survival; Fluorescence; Folic Acid; Graphite; Humans; MCF-7 Cells; Neoplasms; Quantum Dots; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Theranostic Nanomedicine; X-Ray Diffraction | 2019 |
Combinational Effects of Active Targeting, Shape, and Enhanced Permeability and Retention for Cancer Theranostic Nanocarriers.
Topics: Animals; Cell Line, Tumor; Cell Survival; Drug Carriers; Endocytosis; Female; Folic Acid; Humans; Light; Lipids; Mesoporphyrins; Mice; Mice, Nude; Micelles; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Theranostic Nanomedicine; Transplantation, Heterologous | 2019 |
Multifunctional Thermosensitive Liposomes Based on Natural Phase-Change Material: Near-Infrared Light-Triggered Drug Release and Multimodal Imaging-Guided Cancer Combination Therapy.
Topics: Animals; Cell Survival; Doxorubicin; Female; Folic Acid; Gadolinium; HeLa Cells; Humans; Indocyanine Green; Infrared Rays; Liposomes; Magnetic Resonance Imaging; Mice; Mice, Nude; Nanostructures; Neoplasms; Photochemotherapy; Phototherapy; Reactive Oxygen Species; Transplantation, Heterologous | 2019 |
Folate receptors and transporters: biological role and diagnostic/therapeutic targets in cancer and other diseases.
Topics: Folic Acid; Humans; Inflammation; Neoplasms | 2019 |
Cryodesiccation-driven crystallization preparation approach for zinc(II)-phthalocyanine nanodots in cancer photodynamic therapy and photoacoustic imaging.
Topics: Animals; Cell Line, Tumor; Contrast Media; Crystallization; Drug Carriers; Folic Acid; Humans; Indoles; Infrared Rays; Isoindoles; Mice, Inbred BALB C; Neoplasms; Organometallic Compounds; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Poloxamer; Quantum Dots; Singlet Oxygen; Zinc Compounds | 2019 |
Magnetic bio-metal-organic framework nanocomposites decorated with folic acid conjugated chitosan as a promising biocompatible targeted theranostic system for cancer treatment.
Topics: Animals; Biocompatible Materials; Cell Death; Cell Line, Tumor; Cell Survival; Chitosan; Curcumin; Drug Liberation; Erythrocytes; Ferric Compounds; Fluorouracil; Folic Acid; Hemolysis; Humans; Magnetic Resonance Imaging; Magnetics; Metal-Organic Frameworks; Mice; Mice, Inbred BALB C; Nanocomposites; Neoplasms; NIH 3T3 Cells; Phantoms, Imaging; Protein Corona; Theranostic Nanomedicine; X-Ray Diffraction | 2019 |
Preparation of a Ruthenium-Complex-Functionalized Two-Photon-Excited Red Fluorescence Silicon Nanoparticle Composite for Targeted Fluorescence Imaging and Photodynamic Therapy in Vitro.
Topics: Animals; Cell Survival; Coordination Complexes; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Mice; Mice, Nude; Microwaves; Nanoparticles; Neoplasms; Optical Imaging; Photochemotherapy; Ruthenium; Silicon; Singlet Oxygen; Toxicity Tests; Zebrafish | 2019 |
pH-Activatable tumor-targeting gold nanoprobe for near-infrared fluorescence/CT dual-modal imaging in vivo.
Topics: A549 Cells; Animals; Carbocyanines; Cell Death; Folic Acid; Gold; HeLa Cells; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Spectroscopy, Near-Infrared; Thioctic Acid; Tissue Distribution; Tomography, X-Ray Computed | 2019 |
Targeted Transmembrane Delivery of Ca
Topics: Animals; Calcium; Cell Line, Tumor; Cell Proliferation; Cell Survival; Doxorubicin; Drug Carriers; Fluorouracil; Folic Acid; HeLa Cells; Humans; Hydrogels; Hydrogen-Ion Concentration; Ions; Metal Nanoparticles; Mice; Neoplasms; Xenograft Model Antitumor Assays | 2019 |
Plug-and-Play Continuous Gas Flow Assembly of Cysteine-Inserted AuCu Nanobimetals for Folate-Receptor-Targeted Chemo-Phototherapy.
Topics: Cell Line, Tumor; Copper; Cysteine; Doxorubicin; Drug Delivery Systems; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Gases; Gold; Humans; Light; Neoplasms; Nitrogen; Phototherapy; Solutions | 2019 |
Tumour-targeting photosensitisers for one- and two-photon activated photodynamic therapy.
Topics: Biotin; Cell Death; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Neoplasms; Photochemotherapy; Photons; Photosensitizing Agents; Porphyrins | 2019 |
Combinatorial siRNA Polyplexes for Receptor Targeting.
Topics: Cell Line, Tumor; Drug Delivery Systems; Folate Receptor 1; Folic Acid; Gene Silencing; Humans; Neoplasms; Polyethylene Glycols; Polymers; RNA, Small Interfering | 2019 |
Regulation of CAR T cell-mediated cytokine release syndrome-like toxicity using low molecular weight adapters.
Topics: Animals; Cell Engineering; Cell Line, Tumor; Cytokines; Fluorescein; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Immune System Diseases; Immunotherapy, Adoptive; Lymphocyte Activation; Mice; Neoplasms; Receptors, Chimeric Antigen; Single-Chain Antibodies; Syndrome; T-Lymphocytes; Xenograft Model Antitumor Assays | 2019 |
Folate-Decorated Amphiphilic Cyclodextrins as Cell-Targeted Nanophototherapeutics.
Topics: Cyclodextrins; Drug Delivery Systems; Folic Acid; Humans; MCF-7 Cells; Neoplasms; PC-3 Cells; Photochemotherapy | 2019 |
Sandwich-Structured Upconversion Nanoprobes Coated with a Thin Silica Layer for Mitochondria-Targeted Cooperative Photodynamic Therapy for Solid Malignant Tumors.
Topics: Animals; Cell Proliferation; Folic Acid; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Reactive Oxygen Species; Silicon Dioxide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Versatile and Finely Tuned Albumin Nanoplatform based on Click Chemistry.
Topics: Albumins; Animals; Click Chemistry; Copper Radioisotopes; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Half-Life; Isotope Labeling; Mice; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy; Theranostic Nanomedicine; Tissue Distribution | 2019 |
A folic acid-functionalized dual-emissive nanoprobe for "double-check" luminescence imaging of cancer cells.
Topics: Buffers; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Luminescence; Nanoparticles; Nanotechnology; Neoplasms; Optical Imaging; Photochemistry; Rhodamines; Silicon Dioxide | 2019 |
pH-dependent and cathepsin B activable CaCO
Topics: Animals; Calcium Carbonate; Cathepsin B; Diagnostic Imaging; Fluorescent Dyes; Folic Acid; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Mice; Nanoparticles; Neoplasms; Organ Specificity; Polyethylene Glycols | 2019 |
Detecting Functional and Accessible Folate Receptor Expression in Cancer and Polycystic Kidneys.
Topics: A549 Cells; Animals; Doxycycline; Fluorescein-5-isothiocyanate; Folate Receptor 1; Folic Acid; HeLa Cells; Humans; Lysine; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, Transgenic; Molecular Targeted Therapy; Neoplasms; Oligopeptides; Polycystic Kidney Diseases; Protein Kinase C; Tissue Distribution; Trityl Compounds; Xenograft Model Antitumor Assays | 2019 |
Chemotherapeutic drug delivery to cancer cells using a combination of folate targeting and tumor microenvironment-sensitive polypeptides.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Survival; Cell-Penetrating Peptides; Docetaxel; Drug Carriers; Drug Delivery Systems; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Ligands; Matrix Metalloproteinases; Mice; Mice, Nude; Molecular Sequence Data; Nanostructures; Neoplasms; Phosphatidylethanolamines; Polyethylene Glycols; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spheroids, Cellular; Taxoids; Tumor Microenvironment | 2013 |
Gemcitabine-loaded smart carbon nanotubes for effective targeting to cancer cells.
Topics: Cell Line, Tumor; Chemistry, Pharmaceutical; Deoxycytidine; Drug Carriers; Drug Delivery Systems; Folic Acid; Gemcitabine; Humans; MCF-7 Cells; Nanotubes, Carbon; Neoplasms; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2013 |
Targeted tumor computed tomography imaging using low-generation dendrimer-stabilized gold nanoparticles.
Topics: Contrast Media; Dendrimers; Folic Acid; Gold; Humans; KB Cells; Metal Nanoparticles; Neoplasms; Tomography, X-Ray Computed; X-Rays | 2013 |
pH-responsive complexes using prefunctionalized polymers for synchronous delivery of doxorubicin and siRNA to cancer cells.
Topics: Animals; Doxorubicin; Drug Delivery Systems; Endosomes; Female; Folic Acid; Gene Silencing; Gene Transfer Techniques; HeLa Cells; Humans; Hydrazones; Hydrogen-Ion Concentration; Intracellular Space; Ligands; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Polyethylene Glycols; Polyethyleneimine; RNA, Small Interfering; Tissue Distribution | 2013 |
Targeting CCL21-folic acid-upconversion nanoparticles conjugates to folate receptor-α expressing tumor cells in an endothelial-tumor cell bilayer model.
Topics: Cell Death; Cell Line, Tumor; Cell Movement; Chemokine CCL21; Drug Delivery Systems; Endothelial Cells; Female; Folate Receptor 1; Folic Acid; Human Umbilical Vein Endothelial Cells; Humans; Models, Biological; Nanoparticles; Neoplasms; Porosity; Silicon Dioxide; Spectrometry, Fluorescence | 2013 |
Therapeutic targeting of chitosan-PEG-folate-complexed oncolytic adenovirus for active and systemic cancer gene therapy.
Topics: Adaptive Immunity; Adenoviridae; Animals; Chitosan; Folic Acid; Genetic Therapy; Male; Mice; Mice, Nude; Neoplasms; Oncolytic Virotherapy; Oncolytic Viruses; Polyethylene Glycols | 2013 |
Folic acid conjugated glycol chitosan micelles for targeted delivery of doxorubicin: preparation and preliminary evaluation in vitro.
Topics: Antibiotics, Antineoplastic; Cell Survival; Chitosan; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Micelles; Neoplasms | 2013 |
Targeted CT/MR dual mode imaging of tumors using multifunctional dendrimer-entrapped gold nanoparticles.
Topics: Animals; Cell Death; Cell Line, Tumor; Dendrimers; Disease Models, Animal; Folic Acid; Gold; Humans; Magnetic Resonance Imaging; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Particle Size; Signal-To-Noise Ratio; Spectrophotometry, Ultraviolet; Tissue Distribution; Tomography, X-Ray Computed; X-Rays | 2013 |
A simple and rapid electrochemical strategy for non-invasive, sensitive and specific detection of cancerous cell.
Topics: Biosensing Techniques; Electrochemical Techniques; Ferrous Compounds; Folic Acid; Folic Acid Transporters; Gold; HEK293 Cells; HeLa Cells; Humans; Metal Nanoparticles; Metallocenes; Neoplasms | 2013 |
A multifunctional nanoprobe based on Au-Fe3O4 nanoparticles for multimodal and ultrasensitive detection of cancer cells.
Topics: Animals; Benzidines; Colorimetry; Europium; Fluorescein-5-isothiocyanate; Folic Acid; Folic Acid Transporters; Gold; HeLa Cells; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Neoplasms; NIH 3T3 Cells; Optical Imaging; Picolinic Acids | 2013 |
Folate-conjugated PEG on single walled carbon nanotubes for targeting delivery of Doxorubicin to cancer cells.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Cell Death; Cell Survival; Doxorubicin; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Mice; Nanotubes, Carbon; Neoplasms; Polyethylene Glycols; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Static Electricity | 2013 |
Evaluation of folate conjugated superparamagnetic iron oxide nanoparticles for scintigraphic/magnetic resonance imaging.
Topics: Animals; Cell Death; Cell Line; Cell Survival; Dextrans; Ferric Compounds; Folic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetite Nanoparticles; Magnetometry; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Particle Size; Phantoms, Imaging; Rabbits; Radionuclide Imaging; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Static Electricity; Tissue Distribution; Vibration; X-Ray Diffraction | 2013 |
Development of tumor-targeted near infrared probes for fluorescence guided surgery.
Topics: Animals; Female; Fluorescence; Fluorescent Dyes; Folic Acid; Glutarates; Humans; Infrared Rays; KB Cells; Mammary Neoplasms, Experimental; Mice; Mice, Inbred DBA; Molecular Structure; Neoplasms; Tumor Cells, Cultured; Urea | 2013 |
Highly sensitive electrochemiluminescent cytosensing using carbon nanodot@Ag hybrid material and graphene for dual signal amplification.
Topics: Animals; Biomarkers, Tumor; Biosensing Techniques; Carbon; Electrochemical Techniques; Folic Acid; Folic Acid Transporters; Graphite; HeLa Cells; Humans; MCF-7 Cells; Mice; Nanocomposites; Neoplasms; NIH 3T3 Cells; Silver | 2013 |
Targeted molecular therapy for lung cancer: exuberance reestablished.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation, Preclinical; Female; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms; Male; Neoplasms | 2013 |
Improved PET imaging of tumors in mice using a novel (18) F-folate conjugate with an albumin-binding entity.
Topics: Albumins; Animals; Cell Line, Tumor; Female; Fluorodeoxyglucose F18; Folic Acid; Humans; Mice; Mice, Nude; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution | 2013 |
Fluorescent multiblock π-conjugated polymer nanoparticles for in vivo tumor targeting.
Topics: Animals; Cell Line, Tumor; Fluorescent Dyes; Folic Acid; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasms; Optical Imaging; Polymers; Whole Body Imaging | 2013 |
Phospholipid-functionalized mesoporous silica nanocarriers for selective photodynamic therapy of cancer.
Topics: Animals; Antineoplastic Agents; Cell Survival; Drug Carriers; Endocytosis; Fluorescence; Folic Acid; HeLa Cells; Humans; Immunohistochemistry; Intracellular Space; Male; Melanoma, Experimental; Mice; Mice, Nude; Nanoparticles; Neoplasms; Phospholipids; Photochemotherapy; Porosity; Protoporphyrins; Silicon Dioxide | 2013 |
Functionalized magnetic nanoparticles as vehicles for the delivery of the antitumor drug gemcitabine to tumor cells. Physicochemical in vitro evaluation.
Topics: Acrylic Resins; Adsorption; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Deoxycytidine; Drug Delivery Systems; Electrophoresis; Folic Acid; Gemcitabine; Humans; Hydrogen-Ion Concentration; Magnetite Nanoparticles; Microscopy, Confocal; Neoplasms; Optical Imaging; Particle Size | 2013 |
Avidity modulation of folate-targeted multivalent dendrimers for evaluating biophysical models of cancer targeting nanoparticles.
Topics: Dendrimers; Drug Carriers; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Nanoparticles; Neoplasms; Polyamines | 2013 |
Folate-based near-infrared fluorescent theranostic gemcitabine delivery.
Topics: Animals; Antimetabolites, Antineoplastic; Carbocyanines; Deoxycytidine; Drug Carriers; Drug Delivery Systems; Fluorescent Dyes; Folic Acid; Gemcitabine; Humans; KB Cells; Mice; Neoplasms; Optical Imaging; Sulfhydryl Compounds | 2013 |
Folate grafted Prussian Blue entrapped with gadolinium(III) as a new contrast agent for tumor-targeted magnetic resonant imaging.
Topics: Animals; Cell Line; Colloids; Contrast Media; Dose-Response Relationship, Drug; Female; Ferrocyanides; Folic Acid; Gadolinium; Ions; Kidney; Ligands; Magnetic Resonance Imaging; Magnetics; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasm Transplantation; Neoplasms | 2013 |
Cancer therapy and fluorescence imaging using the active release of doxorubicin from MSPs/Ni-LDH folate targeting nanoparticles.
Topics: Antineoplastic Agents; Cell Survival; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Folic Acid; HEK293 Cells; HeLa Cells; Humans; Hydroxides; Nanospheres; Neoplasms; Optical Imaging | 2013 |
Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging.
Topics: Drug Delivery Systems; Fluorescent Dyes; Folic Acid; Gold; HeLa Cells; Humans; Metal Nanoparticles; Microscopy, Fluorescence; Molecular Imaging; Molecular Structure; Neoplasms; Polymers; Spectroscopy, Fourier Transform Infrared; Staining and Labeling | 2013 |
Effect of folate-targeted nanoparticle size on their rates of penetration into solid tumors.
Topics: Cell Line, Tumor; Fluorescein; Folic Acid; Humans; Molecular Weight; Nanoparticles; Neoplasms; Particle Size; Polyethylene Glycols | 2013 |
Synthesis and activity of a folate targeted monodisperse PEG camptothecin conjugate.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Neoplasms; Polyethylene Glycols; Prodrugs | 2013 |
Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Carrier Proteins; Cell Line, Tumor; Embryonic Stem Cells; Energy Metabolism; Fatty Acids; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Glycine; Humans; Male; Metabolic Flux Analysis; Metabolic Networks and Pathways; Methotrexate; Mice; Multienzyme Complexes; NADP; Neoplasms; Protein Biosynthesis; Purines; Serine; Transferases | 2013 |
Biocompatibility of functionalized boron phosphate (BPO4) nanoparticles for boron neutron capture therapy (BNCT) application.
Topics: Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Folic Acid; Humans; Nanoparticles; Neoplasms; Phosphates | 2014 |
Thermal responsive micelles for dual tumor-targeting imaging and therapy.
Topics: Acrylates; Cell Line, Tumor; Drug Carriers; Drug Evaluation, Preclinical; Folic Acid; Humans; Micelles; Molecular Imaging; Molecular Targeted Therapy; Neoplasms; Polyethylene Glycols; Polymers; Stearates; Temperature | 2013 |
Supramolecular self-assembly forming a multifunctional synergistic system for targeted co-delivery of gene and drug.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; DNA; Drug Delivery Systems; Endocytosis; Folic Acid; gamma-Cyclodextrins; Genetic Therapy; Humans; Models, Molecular; Neoplasms; Paclitaxel; Transfection; Tumor Suppressor Protein p53 | 2014 |
FOLICation: engineering approved drugs as potential p53-MDM2 interaction inhibitors for cancer therapy.
Topics: Clofazimine; Cyclopentanes; Drug Discovery; Folic Acid; Humans; Imidazoles; Indoles; Models, Molecular; Neoplasms; Piperazines; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-mdm2; Spiro Compounds; Tumor Suppressor Protein p53 | 2013 |
Folic acid-chitosan conjugated nanoparticles for improving tumor-targeted drug delivery.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Delivery Systems; Folic Acid; Folic Acid Transporters; Humans; Nanoparticles; Neoplasm Proteins; Neoplasms; Phagocytosis | 2013 |
Polyethylene glycol conjugated polymeric nanocapsules for targeted delivery of quercetin to folate-expressing cancer cells in vitro and in vivo.
Topics: Animals; Cell Line, Tumor; Folic Acid; Humans; In Vitro Techniques; Mice; Microscopy, Atomic Force; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanocapsules; Neoplasms; Polyethylene Glycols; Polymers; Quercetin | 2014 |
Rational combination therapy of vintafolide (EC145) with commonly used chemotherapeutic drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Proliferation; Cisplatin; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Folic Acid; HeLa Cells; Humans; Irinotecan; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neoplasms; Neoplasms, Experimental; Paclitaxel; Taxoids; Topotecan; Treatment Outcome; Vinca Alkaloids; Xenograft Model Antitumor Assays | 2014 |
Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer.
Topics: Aminohydrolases; Cell Death; Cell Line, Transformed; Cell Proliferation; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multienzyme Complexes; Neoplasms; RNA Interference; RNA, Messenger | 2014 |
Targeting-triggered porphysome nanostructure disruption for activatable photodynamic therapy.
Topics: Animals; Cell Line, Tumor; Cell Survival; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lasers; Mice; Mice, Nude; Nanostructures; Neoplasms; Photochemotherapy; Photosensitizing Agents; Porphyrins; Singlet Oxygen; Survival Rate; Transplantation, Heterologous | 2014 |
2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Halogenation; Humans; Methylation; Molecular Docking Simulation; Neoplasms; Quinoxalines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 2014 |
Curcumin and 5-fluorouracil-loaded, folate- and transferrin-decorated polymeric magnetic nanoformulation: a synergistic cancer therapeutic approach, accelerated by magnetic hyperthermia.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line; Combined Modality Therapy; Curcumin; Drug Carriers; Fluorouracil; Folic Acid; Humans; Hyperthermia, Induced; Lactic Acid; Magnetite Nanoparticles; MCF-7 Cells; Mice; Nanoconjugates; Nanomedicine; Nanotechnology; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Transferrin | 2014 |
Recruiting cytotoxic T cells to folate-receptor-positive cancer cells.
Topics: Animals; CD3 Complex; Cell Line, Tumor; Coculture Techniques; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunoglobulin G; Immunotherapy; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms; Rats; Rats, Sprague-Dawley; T-Lymphocytes, Cytotoxic | 2013 |
Synthesis and cellular uptake of folic acid-conjugated cellulose nanocrystals for cancer targeting.
Topics: Animals; Caveolae; Cellulose; Chlorpromazine; Clathrin; Drug Carriers; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Genistein; Humans; Nanoparticles; Neoplasms; Rats; Tumor Cells, Cultured | 2014 |
Magnetic resonance imaging-visible and pH-sensitive polymeric micelles for tumor targeted drug delivery.
Topics: Cell Line, Tumor; Cell Survival; Dextrans; Drug Delivery Systems; Endocytosis; Flow Cytometry; Folic Acid; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetite Nanoparticles; Micelles; Microscopy, Fluorescence; Neoplasms; Particle Size; Peptides; Polyethylene Glycols; Polymers; Staining and Labeling | 2014 |
A fullerene-based multi-functional nanoplatform for cancer theranostic applications.
Topics: Animals; Drug Delivery Systems; Folic Acid; Fullerenes; Humans; Hypothermia, Induced; Magnetic Resonance Imaging; Magnetite Nanoparticles; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanocomposites; Neoplasms; Photochemotherapy; Polyethylene Glycols | 2014 |
Cancer-cell-targeted theranostic cubosomes.
Topics: Antineoplastic Agents; Cryoelectron Microscopy; Drug Delivery Systems; Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Light; Magnetic Resonance Spectroscopy; Microscopy, Confocal; Nanomedicine; Nanoparticles; Neoplasms; Particle Size; Photochemistry; Poloxamer; Scattering, Small Angle; X-Ray Diffraction | 2014 |
Prolonged blood circulation and enhanced tumor accumulation of folate-targeted dendrimer-polymer hybrid nanoparticles.
Topics: Animals; Cell Line, Tumor; Chemistry, Pharmaceutical; Dendrimers; Drug Carriers; Female; Folic Acid; Folic Acid Transporters; Humans; Lactates; Mice, Inbred BALB C; Mice, Nude; Nanomedicine; Nanoparticles; Neoplasms; Particle Size; Polyethylene Glycols; Technology, Pharmaceutical; Tissue Distribution | 2014 |
An intracellularly activatable, fluorogenic probe for cancer imaging.
Topics: Animals; Cathepsin B; Cell Line, Tumor; Chromatography, High Pressure Liquid; Flow Cytometry; Fluorescent Dyes; Folic Acid; Humans; Intracellular Space; Mice; Microscopy, Confocal; Molecular Imaging; Neoplasms; NIH 3T3 Cells; Plasma; Reproducibility of Results; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature; Time Factors | 2014 |
Facile synthesis of multilayered polysaccharidic vesicles.
Topics: Amylases; Animals; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Drug Carriers; Female; Folic Acid; Folic Acid Transporters; Humans; Hyaluronic Acid; Mice, Nude; Neoplasms; Peptides; Polyethylene Glycols; Polylysine; Serum Albumin, Bovine; Starch | 2014 |
Synthesis of luminescent nanoporous silica spheres functionalized with folic acid for targeting to cancer cells.
Topics: Animals; Folic Acid; HeLa Cells; Humans; Luminescence; Mice; Nanospheres; Neoplasms; NIH 3T3 Cells; Porosity; Silicon Dioxide; X-Ray Diffraction | 2014 |
Targeted cancer theranostics using alpha-tocopheryl succinate-conjugated multifunctional dendrimer-entrapped gold nanoparticles.
Topics: Animals; Cell Line, Tumor; Contrast Media; Dendrimers; Folic Acid; Gold; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Polyethylene Glycols; Tomography, X-Ray Computed; Vitamin E | 2014 |
Mesoporous NaYbF4@NaGdF4 core-shell up-conversion nanoparticles for targeted drug delivery and multimodal imaging.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Contrast Media; Doxorubicin; Drug Delivery Systems; Female; Fluorides; Folic Acid; Gadolinium; Humans; Luminescent Agents; Magnetic Resonance Imaging; Mice; Models, Molecular; Multimodal Imaging; Nanoparticles; Neoplasms; Tomography, X-Ray Computed; Yttrium | 2014 |
Oligomeric nanoparticles functionalized with NIR-emitting CdTe/CdS QDs and folate for tumor-targeted imaging.
Topics: Animals; Cadmium Compounds; Diagnostic Imaging; Fluorescence; Folic Acid; Mice, Nude; Nanoparticles; Neoplasms; Optical Imaging; Organ Specificity; Quantum Dots; Spectroscopy, Near-Infrared; Sulfides; Tellurium | 2014 |
Folic acid-functionalized up-conversion nanoparticles: toxicity studies in vivo and in vitro and targeted imaging applications.
Topics: Animals; Biocompatible Materials; Contrast Media; Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Luminescence; MCF-7 Cells; Mice; Microscopy, Electron, Transmission; Molecular Imaging; Nanoparticles; Nanotechnology; Neoplasms; Tissue Distribution | 2014 |
Development of a folate-modified curcumin loaded micelle delivery system for cancer targeting.
Topics: Animals; Cell Death; Cell Survival; Curcumin; Drug Delivery Systems; Endocytosis; Folic Acid; Hemolysis; Hep G2 Cells; Humans; Irritants; Lactic Acid; Male; MCF-7 Cells; Micelles; Microscopy, Fluorescence; Neoplasms; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Rabbits; Rats; Static Electricity; Surface-Active Agents | 2014 |
Actively targeted delivery of anticancer drug to tumor cells by redox-responsive star-shaped micelles.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Female; Flow Cytometry; Folic Acid; Glutathione; Humans; In Situ Nick-End Labeling; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Oxidation-Reduction; Particle Size; Polyesters; Proton Magnetic Resonance Spectroscopy; Tissue Distribution | 2014 |
One-pot synthesis and functionalisation of Fe2O3@C-NH2 nanoparticles for imaging and therapy.
Topics: Amines; Catalysis; Cell Line, Tumor; Ferric Compounds; Folic Acid; Hot Temperature; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; Metal Nanoparticles; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanomedicine; Nanotubes, Carbon; Neoplasms; Polyethylene Glycols; Solubility; Solvents; Surface Properties; Temperature; Time Factors | 2014 |
Folic acid functionalized surface highlights 5-methylcytosine-genomic content within circulating tumor cells.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Blood Chemical Analysis; Cells, Cultured; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Folic Acid; Genes, Neoplasm; Humans; Microscopy, Confocal; Neoplasms; Neoplastic Cells, Circulating; Surface Properties; Survival Analysis | 2014 |
Smart dual-functional warhead for folate receptor-specific activatable imaging and photodynamic therapy.
Topics: Animals; Cathepsin B; Cell Line, Tumor; Cell Survival; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Light; Mice; Neoplasms; Photochemotherapy; Photosensitizing Agents; Porphyrins; Spectrometry, Fluorescence; Spectrophotometry; Transplantation, Heterologous | 2014 |
A folate-integrated magnetic polymer micelle for MRI and dual targeted drug delivery.
Topics: Antibiotics, Antineoplastic; Cell Survival; Doxorubicin; Drug Carriers; Ferrosoferric Oxide; Folic Acid; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; MCF-7 Cells; Micelles; Microscopy, Confocal; Neoplasms; Polymers | 2014 |
Current quandaries in cancer-associated anemia.
Topics: Anemia; Antineoplastic Agents; Folic Acid; Humans; Iron; Neoplasms; Vitamin B 12 | 2014 |
A novel drug delivery system of gold nanorods with doxorubicin and study of drug release by single molecule spectroscopy.
Topics: Antineoplastic Agents; Doxorubicin; Drug Delivery Systems; Drug Liberation; Folic Acid; Folic Acid Transporters; Gold; Humans; KB Cells; Nanotubes; Neoplasms; Optical Imaging; Spectrum Analysis; Thioctic Acid | 2015 |
Folate-targeted multifunctional amino acid-chitosan nanoparticles for improved cancer therapy.
Topics: Amino Acids; Antineoplastic Agents; Chitosan; Coculture Techniques; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Nanoparticles; Neoplasms | 2015 |
Distinguish cancer cells based on targeting turn-on fluorescence imaging by folate functionalized green emitting carbon dots.
Topics: Carbon; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Microscopy, Fluorescence; Nanocomposites; Neoplasms; Optical Imaging | 2015 |
Fabrication of folate bioconjugated near-infrared fluorescent silver nanoclusters for targeted in vitro and in vivo bioimaging.
Topics: 3T3 Cells; Animals; Cell Line, Tumor; Cell Survival; Diagnostic Imaging; Fluorescence; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Mice; Microscopy, Electron, Transmission; Nanostructures; Neoplasms; Photoelectron Spectroscopy; Polyethyleneimine; Silver; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Sulfhydryl Compounds; Tissue Distribution | 2014 |
Efficient rejection-based simulation of biochemical reactions with stochastic noise and delays.
Topics: Algorithms; Biochemical Phenomena; Computer Simulation; Folic Acid; Humans; MAP Kinase Signaling System; Models, Biological; Models, Chemical; Neoplasms; Stochastic Processes | 2014 |
A monomeric photosensitizer for targeted cancer therapy.
Topics: Animals; Drug Carriers; Folic Acid; Hep G2 Cells; Humans; Indoles; Isoindoles; Male; Mice, Inbred BALB C; Micelles; Neoplasms; Optical Imaging; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Povidone; Singlet Oxygen; Sunlight; Zinc Compounds | 2014 |
Multifunctional near infrared-emitting long-persistence luminescent nanoprobes for drug delivery and targeted tumor imaging.
Topics: Animals; Cell Death; Diagnostic Imaging; Doxorubicin; Drug Delivery Systems; Folic Acid; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Luminescence; Male; Mice; Nanospheres; Neoplasms; Porosity; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared; Surface Properties | 2015 |
Gold nanocluster-based fluorescence biosensor for targeted imaging in cancer cells and ratiometric determination of intracellular pH.
Topics: A549 Cells; Biosensing Techniques; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; Gold; HeLa Cells; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Neoplasms; Optical Imaging; Spectrometry, Fluorescence | 2015 |
Poly(l-lysine)-graft-folic acid-coupled poly(2-methyl-2-oxazoline) (PLL-g-PMOXA-c-FA): a bioactive copolymer for specific targeting to folate receptor-positive cancer cells.
Topics: Biosensing Techniques; Cell Line, Tumor; Folate Receptor 1; Folic Acid; Humans; Kinetics; Neoplasms; Polyamines; Polylysine; Polymers | 2015 |
Folate-bovine serum albumin functionalized polymeric micelles loaded with superparamagnetic iron oxide nanoparticles for tumor targeting and magnetic resonance imaging.
Topics: Animals; Cattle; Cell Death; Cell Line, Tumor; Dextrans; Folic Acid; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Polymers; Proton Magnetic Resonance Spectroscopy; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Static Electricity; Xenograft Model Antitumor Assays | 2015 |
Inorganic photosensitizer coupled Gd-based upconversion luminescent nanocomposites for in vivo magnetic resonance imaging and near-infrared-responsive photodynamic therapy in cancers.
Topics: Animals; Cell Death; Cell Survival; Female; Folic Acid; Gadolinium; HeLa Cells; Humans; Luminescence; Magnetic Resonance Imaging; MCF-7 Cells; Mice; Mice, Nude; Nanocomposites; Neoplasms; Photochemotherapy; Photosensitizing Agents; Scattering, Radiation; Silicon Dioxide; Spectroscopy, Near-Infrared; Static Electricity; Titanium; X-Ray Diffraction | 2015 |
Folate-grafted boron nitride nanotubes: possible exploitation in cancer therapy.
Topics: Boron Compounds; Cell Survival; Drug Carriers; Folic Acid; HeLa Cells; Humans; Microscopy, Confocal; Nanotubes; Neoplasms | 2015 |
Design and synthesis of a multivalent fluorescent folate-calix[4]arene conjugate: cancer cell penetration and intracellular localization.
Topics: Animals; Calixarenes; Cell Line, Tumor; Drug Design; Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Mice; Molecular Structure; Neoplasms; NIH 3T3 Cells; Phenols | 2015 |
Indocyanine green targeted micelles with improved stability for near-infrared image-guided photothermal tumor therapy.
Topics: Animals; Cell Line, Tumor; Coloring Agents; Drug Delivery Systems; Folic Acid; Humans; Hyperthermia, Induced; Indocyanine Green; Mice; Micelles; Neoplasms; Phototherapy; Polyamines; Polyesters | 2015 |
High molecular weight chitosan derivative polymeric micelles encapsulating superparamagnetic iron oxide for tumor-targeted magnetic resonance imaging.
Topics: Animals; Chitosan; Contrast Media; Folic Acid; HeLa Cells; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Micelles; Neoplasms | 2015 |
A functional drug delivery platform for targeting and imaging cancer cells based on Pluronic F127.
Topics: Cell Proliferation; Cells, Cultured; Drug Carriers; Drug Delivery Systems; Drug Evaluation, Preclinical; Fluorescein-5-isothiocyanate; Folic Acid; HeLa Cells; Humans; Micelles; Neoplasms; Optical Imaging; Poloxamer; Solanaceous Alkaloids | 2015 |
Blended nanoparticle system based on miscible structurally similar polymers: a safe, simple, targeted, and surprisingly high efficiency vehicle for cancer therapy.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Delivery Systems; Drug Resistance, Neoplasm; Endocytosis; Female; Folic Acid; HeLa Cells; Humans; MCF-7 Cells; Mice; Mice, SCID; Nanoparticles; Neoplasms; Particle Size; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polymers; Taxoids; Vitamin E | 2015 |
Vitamin Bc -Bearing Hydrophilic Photosensitizer Conjugate for Photodynamic Cancer Theranostics.
Topics: Animals; Cell Line, Tumor; Chlorophyll; Folic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Theranostic Nanomedicine; Thiamine; Xenograft Model Antitumor Assays | 2015 |
Folic acid in pregnancy and mortality from cancer and cardiovascular disease: further follow-up of the Aberdeen folic acid supplementation trial.
Topics: Adult; Breast Neoplasms; Cardiovascular Diseases; Cause of Death; Female; Folic Acid; Follow-Up Studies; Hematinics; Humans; Long Term Adverse Effects; Neoplasms; Neural Tube Defects; Pregnancy; Randomized Controlled Trials as Topic; Registries; Risk Factors; Scotland | 2015 |
Fabrication and spectroscopic studies of folic acid-conjugated Fe3O4@Au core-shell for targeted drug delivery application.
Topics: Antineoplastic Agents; Cysteine; Drug Carriers; Drug Delivery Systems; Folic Acid; Gold; Humans; Magnetite Nanoparticles; Neoplasms; Powder Diffraction; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2015 |
Targeted tumor theranostics using folate-conjugated and camptothecin-loaded acoustic nanodroplets in a mouse xenograft model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Folic Acid; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Nanostructures; Neoplasms; Theranostic Nanomedicine; Xenograft Model Antitumor Assays | 2015 |
Reversible lysine modification on proteins by using functionalized boronic acids.
Topics: Alkynes; Animals; Antineoplastic Agents, Phytogenic; Azides; Boronic Acids; Cell Line; Cell Line, Tumor; Folic Acid; Humans; Imines; Insulin; Lysine; Models, Molecular; Muramidase; Neoplasms; Paclitaxel; Polyethylene Glycols; Proteins | 2015 |
The effect of ligand density on in vivo tumor targeting of nanographene oxide.
Topics: Animals; Folic Acid; Folic Acid Transporters; Graphite; Humans; KB Cells; Laser Therapy; Ligands; Male; MCF-7 Cells; Mice; Mice, Nude; Nanostructures; Neoplasms; NIH 3T3 Cells; Oxides; Phototherapy; Poloxamer; Tumor Burden | 2015 |
Programmed packaging of mesoporous silica nanocarriers for matrix metalloprotease 2-triggered tumor targeting and release.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Culture Media, Conditioned; Doxorubicin; Drug Carriers; Endocytosis; Folic Acid; Gelatin; HT29 Cells; Humans; Ligands; Liver; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Nanoparticles; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Silicon Dioxide | 2015 |
Folic acid supplementation in vitro induces cell type-specific changes in BRCA1 and BRCA 2 mRNA expression, but does not alter DNA methylation of their promoters or DNA repair.
Topics: BRCA1 Protein; BRCA2 Protein; Cell Line, Tumor; CpG Islands; Dietary Supplements; DNA Methylation; DNA Repair; Epigenesis, Genetic; Folic Acid; Humans; Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Vitamin B Complex | 2015 |
Tumor-Targeting Co-Delivery of Drug and Gene from Temperature-Triggered Micelles.
Topics: Antineoplastic Agents; Combined Modality Therapy; Drug Carriers; Folic Acid; Gene Transfer Techniques; HeLa Cells; Humans; Micelles; Neoplasms; Poloxamer; Polyethyleneimine; Temperature; Transgenes | 2015 |
Comparison of nanoparticle penetration into solid tumors and sites of inflammation: studies using targeted and nontargeted liposomes.
Topics: Animals; Colitis, Ulcerative; Drug Delivery Systems; Folic Acid; Liposomes; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Nanoparticles; Neoplasms; Tissue Distribution | 2015 |
Cancer targeting propensity of folate conjugated surface engineered multi-walled carbon nanotubes.
Topics: Animals; Cell Line, Tumor; Folic Acid; Humans; Mice; Mice, Inbred BALB C; Microscopy, Atomic Force; Microscopy, Electron; Nanotubes, Carbon; Neoplasms; Surface Properties; X-Ray Diffraction | 2015 |
Photoluminescent carbon dots synthesized by microwave treatment for selective image of cancer cells.
Topics: Biocompatible Materials; Carbon; Cell Line; Diagnostic Imaging; Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Luminescence; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Microwaves; Nanotechnology; Neoplasms; Photochemistry; Quantum Dots; Solvents; Urea; Water; X-Ray Diffraction | 2015 |
Size- and shape-dependent peroxidase-like catalytic activity of MnFe2O4 Nanoparticles and their applications in highly efficient colorimetric detection of target cancer cells.
Topics: Animals; Benzidines; Catalysis; Cell Survival; Colorimetry; Ferric Compounds; Fluorescein-5-isothiocyanate; Folic Acid; Folic Acid Transporters; HeLa Cells; Humans; Hydrogen Peroxide; Manganese Compounds; Metal Nanoparticles; Mice; Neoplasms; NIH 3T3 Cells; Peroxidase | 2015 |
Folic acid functionalized ZnO quantum dots for targeted cancer cell imaging.
Topics: Cell Survival; Folic Acid; HEK293 Cells; Humans; Luminescent Measurements; MCF-7 Cells; Microscopy, Confocal; Neoplasms; Quantum Dots; Zinc Oxide | 2015 |
Folate receptor-targeted radionuclide therapy: preclinical investigation of anti-tumor effects and potential radionephropathy.
Topics: Animals; Biological Transport; Body Weight; Cell Survival; Coordination Complexes; Female; Folic Acid; Folic Acid Transporters; Humans; KB Cells; Kidney; Kidney Diseases; Leukocytes; Mice; Mice, Nude; Neoplasms; Radiation Injuries; Radiometry; Radiopharmaceuticals; Survival Analysis; Technetium Tc 99m Dimercaptosuccinic Acid | 2015 |
Synthesis and characterization of pH-sensitive poly(itaconic acid)-poly(ethylene glycol)-folate-poly(l-histidine) micelles for enhancing tumor therapy and tunable drug release.
Topics: Antineoplastic Agents; Cell Survival; Drug Delivery Systems; Drug Liberation; Folic Acid; HeLa Cells; Histidine; Humans; Hydrogen-Ion Concentration; Micelles; Neoplasms; Polyethylene Glycols; Succinates | 2015 |
Folate-conjugated chitosan-poly(ethylenimine) copolymer as an efficient and safe vector for gene delivery in cancer cells.
Topics: Animals; Aziridines; Cell Line, Tumor; Chitosan; Folate Receptors, GPI-Anchored; Folic Acid; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Melanoma, Experimental; Mice; Neoplasms; Polymers; Transfection | 2015 |
Molecular Modeling Investigation of Folic Acid Conjugation to MDM2 Inhibitors for Enhanced Cellular Uptake and Target Binding.
Topics: Animals; Drug Design; Folic Acid; Folic Acid Transporters; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Docking Simulation; Neoplasms; Protein Binding; Proto-Oncogene Proteins c-mdm2 | 2015 |
A novel Trojan-horse targeting strategy to reduce the non-specific uptake of nanocarriers by non-cancerous cells.
Topics: Acrylic Resins; Animals; Contrast Media; Drug Carriers; Endocytosis; Fatty Acids; Female; Ferric Compounds; Folic Acid; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; MCF-7 Cells; Methacrylates; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Polymerization; Temperature; Time Factors | 2015 |
Smart IR780 Theranostic Nanocarrier for Tumor-Specific Therapy: Hyperthermia-Mediated Bubble-Generating and Folate-Targeted Liposomes.
Topics: Animals; Binding, Competitive; Cell Death; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; Hyperthermia, Induced; Indoles; Liposomes; Mice, Inbred BALB C; Mice, Nude; Microbubbles; Nanoparticles; Neoplasms; Particle Size; Phototherapy; Surface Properties; Temperature; Theranostic Nanomedicine; Tissue Distribution; Titanium; Treatment Outcome | 2015 |
Detection of folic acid protein in human serum using reduced graphene oxide electrodes modified by folic-acid.
Topics: Biomarkers, Tumor; Biosensing Techniques; Electrodes; Folic Acid; Folic Acid Transporters; Gold; Graphite; Humans; Limit of Detection; Neoplasms; Oxides | 2016 |
Plasma Folate, Vitamin B12 and Homocysteine Levels in Children with Solid Tumors at Diagnosis; Results from a Pediatric Referral Centre.
Topics: Carcinogenesis; Case-Control Studies; Child, Preschool; Female; Folic Acid; Folic Acid Deficiency; Greece; Homocysteine; Humans; Male; Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 2016 |
Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Arginine; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Drug Carriers; Female; Fluorescein-5-isothiocyanate; Folic Acid; Glutamic Acid; HEK293 Cells; Humans; Lethal Dose 50; Male; Mice; Mice, Nude; Molecular Weight; Neoplasms; Paclitaxel; Prodrugs; Solubility; Toxicity Tests, Acute; Xenograft Model Antitumor Assays | 2015 |
Doxorubicin-Loaded Micelles Based on Folic Acid Conjugated pH-Dependent Thermo-Sensitive Copolymer: In Vitro and In Vivo Evaluation.
Topics: Animals; Antibiotics, Antineoplastic; Cell Survival; Delayed-Action Preparations; Diffusion; Doxorubicin; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Male; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanocapsules; Nanoconjugates; Neoplasms; Particle Size; Temperature; Treatment Outcome | 2015 |
Compilation of a standardised international folate database for EPIC.
Topics: Databases, Factual; Diet; Europe; Folic Acid; Food; Humans; Neoplasms; Nutrition Assessment; Nutritional Physiological Phenomena; Prospective Studies; Reference Standards | 2016 |
In vivo dual-targeted chemotherapy of drug resistant cancer by rationally designed nanocarrier.
Topics: Animals; Antineoplastic Agents; Doxorubicin; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Egg Yolk; Ferric Compounds; Flow Cytometry; Folic Acid; Hep G2 Cells; Humans; Intracellular Space; Magnesium Silicates; Magnetic Phenomena; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Polyethylene Glycols; Porosity; Temperature; X-Ray Diffraction | 2016 |
Supplemental folic acid in pregnancy and maternal cancer risk.
Topics: Adult; Cohort Studies; Dietary Supplements; Female; Folic Acid; Humans; Neoplasms; Norway; Pregnancy; Proportional Hazards Models; Registries; Risk | 2015 |
Characterization and evaluation of a folic acid receptor-targeted cyclodextrin complex as an anticancer drug delivery system.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cyclodextrins; Docetaxel; Drug Carriers; Female; Folic Acid; Folic Acid Transporters; Humans; Mice, Inbred BALB C; Molecular Targeted Therapy; Neoplasms; Solubility; Taxoids; Tissue Distribution | 2016 |
Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR).
Topics: Animals; Carbon; DNA Damage; DNA Methylation; Folic Acid; Genotype; Glycine N-Methyltransferase; Hep G2 Cells; Homocysteine; Humans; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Neoplasms; Nucleotides; Nutritional Status; Purines; S-Adenosylmethionine; Uracil | 2015 |
Multifunctional Nanostructures for Tumor-Targeted Molecular Imaging and Photodynamic Therapy.
Topics: Folic Acid; Humans; Indocyanine Green; Magnetic Resonance Imaging; Molecular Imaging; Nanostructures; Neoplasms; Photochemotherapy; Polyethylene Glycols; Polyethyleneimine | 2016 |
Multifunctional nanosheets based on folic acid modified manganese oxide for tumor-targeting theranostic application.
Topics: Antineoplastic Agents; Cell Survival; Doxorubicin; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Manganese Compounds; Nanoshells; Neoplasms; Oxides; Particle Size; Theranostic Nanomedicine; Treatment Outcome; Xenograft Model Antitumor Assays | 2016 |
A pH-responsive folate conjugated magnetic nanoparticle for targeted chemo-thermal therapy and MRI diagnosis.
Topics: Antibiotics, Antineoplastic; Apoptosis; Contrast Media; Doxorubicin; Drug Carriers; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Magnetic Resonance Imaging; Magnetite Nanoparticles; Microscopy, Confocal; Neoplasms; Radiography; Spectroscopy, Fourier Transform Infrared; Temperature | 2016 |
A Novel Folate-Targeted Nanoliposomal System of Doxorubicin for Cancer Targeting.
Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Line, Tumor; Cholesterol; Doxorubicin; Drug Delivery Systems; Female; Folic Acid; Humans; Ligands; Liposomes; Mice; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Tissue Distribution | 2016 |
Design, preparation, and in vitro characterization of a trimodally-targeted nanomagnetic onco-theranostic system for cancer diagnosis and therapy.
Topics: Animals; Antibiotics, Antineoplastic; Cell Survival; Chitosan; Doxorubicin; Drug Compounding; Drug Design; Drug Liberation; Folic Acid; Folic Acid Transporters; Humans; Hydrogen-Ion Concentration; Hyperthermia, Induced; Magnetic Phenomena; Magnetite Nanoparticles; MCF-7 Cells; Mice; Neoplasms; NIH 3T3 Cells; Theranostic Nanomedicine | 2016 |
Serum folate levels and fatality among diabetic adults: A 15-y follow-up study of a national cohort.
Topics: Aged; Cardiovascular Diseases; Cotinine; Diabetes Mellitus; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Nutrition Surveys; Proportional Hazards Models; Retrospective Studies; Risk Factors; Socioeconomic Factors; Vitamin B 12 | 2016 |
Supplemental folic acid in pregnancy and childhood cancer risk.
Topics: Adolescent; Adult; Cohort Studies; Dietary Supplements; Female; Folic Acid; Humans; Middle Aged; Neoplasms; Pregnancy; Risk | 2016 |
Targeting of pegylated liposomal mitomycin-C prodrug to the folate receptor of cancer cells: Intracellular activation and enhanced cytotoxicity.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Cholesterol; Female; Folic Acid; Folic Acid Transporters; Humans; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Molecular Targeted Therapy; Neoplasms; Peritoneal Diseases; Phosphatidylethanolamines; Polyethylene Glycols; Prodrugs | 2016 |
Zinc finger-inspired nanohydrogels with glutathione/pH triggered degradation based on coordination substitution for highly efficient delivery of anti-cancer drugs.
Topics: Animals; Antineoplastic Agents; Cell Survival; Doxorubicin; Drug Delivery Systems; Drug Liberation; Female; Folic Acid; Glutathione; HEK293 Cells; HeLa Cells; Humans; Hydrogels; Hydrogen-Ion Concentration; Mice, Inbred BALB C; Nanostructures; Neoplasms; Polyethylene Glycols; Polymethacrylic Acids; Tumor Burden; Zinc; Zinc Fingers | 2016 |
PEGylated polyethylenimine-entrapped gold nanoparticles modified with folic acid for targeted tumor CT imaging.
Topics: Animals; Cell Line, Tumor; Cell Survival; Colloids; Contrast Media; Folate Receptors, GPI-Anchored; Folic Acid; Gold; Humans; Metal Nanoparticles; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Microscopy, Confocal; Microscopy, Electron, Transmission; Neoplasms; Polyethylene Glycols; Polyethyleneimine; Solubility; Tomography, X-Ray Computed; Transplantation, Heterologous | 2016 |
Development and validation of a UPLC-MS/MS method for the novel folate-targeted small molecule drug conjugate EC1456 and its metabolites in tumor homogenates from mice.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Folic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oligopeptides; Pharmaceutical Preparations; Pipecolic Acids; Small Molecule Libraries; Tandem Mass Spectrometry | 2016 |
Imaging-guided photoacoustic drug release and synergistic chemo-photoacoustic therapy with paclitaxel-containing nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Delivery Systems; Female; Fluorocarbons; Folic Acid; Gold; HeLa Cells; Humans; Low-Level Light Therapy; Mice; Mice, Inbred BALB C; Nanoparticles; Nanotubes; Neoplasms; NIH 3T3 Cells; Paclitaxel; Photoacoustic Techniques; Volatilization | 2016 |
Fluoridated hydroxyapatite: Eu(3+) nanorods-loaded folate-conjugated D-α-tocopheryl polyethylene glycol succinate (vitamin E TPGS) micelles for targeted imaging of cancer cells.
Topics: Cell Survival; Diagnostic Imaging; Drug Stability; Folic Acid; Humans; Hydroxyapatites; MCF-7 Cells; Micelles; Nanoconjugates; Nanotubes; Neoplasms; Polyethylene Glycols; Vitamin E | 2016 |
Intake and Biomarkers of Folate and Risk of Cancer Morbidity in Older Adults, NHANES 1999-2002 with Medicare Linkage.
Topics: Aged; Alcohol Drinking; Anthropometry; Biomarkers; Diet; Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Incidence; Life Style; Male; Medicare; Middle Aged; Neoplasms; Nutrition Surveys; Proportional Hazards Models; Risk; Smoking; Socioeconomic Factors; United States | 2016 |
NK Cell-Mediated Antitumor Effects of a Folate-Conjugated Immunoglobulin Are Enhanced by Cytokines.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; Cell Line, Tumor; Cytokines; Cytotoxicity, Immunologic; Disease Models, Animal; Female; Folate Receptor 1; Folic Acid; Gene Expression; Humans; Immunoconjugates; Immunoglobulin G; Immunomodulation; Interleukin-12; Killer Cells, Natural; Lymphocyte Activation; Mice; Monocytes; Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Multiple-Armed Tetrahedral DNA Nanostructures for Tumor-Targeting, Dual-Modality in Vivo Imaging.
Topics: Animals; Cell Line, Tumor; DNA; Fluorescence; Folic Acid; Humans; Mice; Nanostructures; Neoplasms; Spectroscopy, Near-Infrared; Tomography, Emission-Computed, Single-Photon; Xenograft Model Antitumor Assays | 2016 |
Pegylated folate and peptide-decorated graphene oxide nanovehicle for in vivo targeted delivery of anticancer drugs and therapeutic self-monitoring.
Topics: Animals; Antineoplastic Agents; Biosensing Techniques; Cell Line, Tumor; Drug Delivery Systems; Folate Receptor 1; Folic Acid; Graphite; Humans; Mice; Nanoparticles; Neoplasms; Peptides | 2016 |
A magnetic vehicle realized tumor cell-targeted radiotherapy using low-dose radiation.
Topics: Animals; Chitosan; Chlorophyllides; Drug Delivery Systems; Female; Ferric Compounds; Folic Acid; HeLa Cells; Humans; Magnets; Mice, Nude; Micelles; Neoplasms; Porphyrins; Radiation-Sensitizing Agents | 2016 |
In situ crosslinked smart polypeptide nanoparticles for multistage responsive tumor-targeted drug delivery.
Topics: A549 Cells; Anhydrides; Antineoplastic Agents; Cell Line, Tumor; Cross-Linking Reagents; Cyclohexenes; Doxycycline; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Nanoparticles; Nanotechnology; Neoplasms; Oxidation-Reduction; Peptides; Polylysine | 2016 |
An efficient dual-loaded multifunctional nanocarrier for combined photothermal and photodynamic therapy based on copper sulfide and chlorin e6.
Topics: Animals; Cell Survival; Chlorophyllides; Copper; Drug Stability; Female; Folic Acid; HeLa Cells; Humans; Light; Liposomes; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Nanoparticles; Neoplasms; Photochemotherapy; Porphyrins; Reactive Oxygen Species; Solubility | 2016 |
A Dual-Targeting Octaguanidine-Doxorubicin Conjugate Transporter for Inducing Caspase-Mediated Apoptosis on Folate-Expressing Cancer Cells.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Caspases; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Folic Acid; Folic Acid Transporters; Guanidine; Humans; Mice; Mice, Inbred BALB C; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tissue Distribution; Tumor Cells, Cultured | 2016 |
A Drug-Free Tumor Therapy Strategy: Cancer-Cell-Targeting Calcification.
Topics: Animals; Calcification, Physiologic; Calcinosis; Calcium; Cell Death; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; HEK293 Cells; HeLa Cells; Humans; Mice; Neoplasms | 2016 |
Paclitaxel-loaded phosphonated calixarene nanovesicles as a modular drug delivery platform.
Topics: A549 Cells; Antineoplastic Agents; Calixarenes; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Folic Acid; Humans; Hydrogen-Ion Concentration; Nanostructures; Neoplasms; Paclitaxel | 2016 |
Double-Cross-Linked Hyaluronic Acid Nanoparticles with pH/Reduction Dual-Responsive Triggered Release and pH-Modulated Fluorescence for Folate-Receptor-Mediated Targeting Visualized Chemotherapy.
Topics: Antineoplastic Agents; Cell Line, Tumor; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Drug Liberation; Folic Acid; HeLa Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Nanoparticles; Neoplasms; Rhodamines | 2016 |
Synthesis and Preclinical Evaluation of Folate-NOTA-Al(18)F for PET Imaging of Folate-Receptor-Positive Tumors.
Topics: A549 Cells; Animals; Female; Fluorine Radioisotopes; Folate Receptors, GPI-Anchored; Folic Acid; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; KB Cells; Mice; Mice, Nude; Neoplasms; Positron-Emission Tomography; Radiochemistry; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2016 |
Zwitterionic nanogels crosslinked by fluorescent carbon dots for targeted drug delivery and simultaneous bioimaging.
Topics: Animals; Cell Line, Tumor; Dextrans; Drug Delivery Systems; Drug Screening Assays, Antitumor; Folic Acid; Gels; Humans; Mice; Neoplasms; NIH 3T3 Cells; Optical Imaging; Quantum Dots | 2016 |
Magnetically and pH dual responsive dendrosomes for tumor accumulation enhanced folate-targeted hybrid drug delivery.
Topics: A549 Cells; Animals; Cell Survival; Dendrimers; Drug Delivery Systems; Drug Liberation; Female; Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Magnetic Phenomena; Magnetite Nanoparticles; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Rhodamines | 2016 |
Folate deficient tumor microenvironment promotes epithelial-to-mesenchymal transition and cancer stem-like phenotypes.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Epithelial-Mesenchymal Transition; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Humans; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Neoplasms; Neoplastic Stem Cells; Nitrosative Stress; Oxidative Stress; Phenotype; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction; Time Factors; Tumor Microenvironment | 2016 |
Utilizing G2/M retention effect to enhance tumor accumulation of active targeting nanoparticles.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Disease Models, Animal; Docetaxel; Folic Acid; G2 Phase Cell Cycle Checkpoints; Humans; Ligands; Male; Mice; Molecular Imaging; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Polyethylene Glycols; Polymers; Taxoids; Xenograft Model Antitumor Assays | 2016 |
Serum folate concentrations and all-cause, cardiovascular disease and cancer mortality: A cohort study based on 1999-2010 National Health and Nutrition Examination Survey (NHANES).
Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Cohort Studies; Female; Folic Acid; Follow-Up Studies; Humans; Male; Middle Aged; Mortality; Neoplasms; Nutrition Surveys; Prospective Studies | 2016 |
Multifunctional Fe3O4 @ Au core/shell nanostars: a unique platform for multimode imaging and photothermal therapy of tumors.
Topics: Animals; Contrast Media; Ferrosoferric Oxide; Folic Acid; Gold; HeLa Cells; Humans; Laser Therapy; Magnetic Resonance Imaging; Mice; Nanoparticles; Neoplasms; Phototherapy; Theranostic Nanomedicine; Tomography, X-Ray Computed; Xenograft Model Antitumor Assays | 2016 |
Synthesis and Evaluation of (99m)Tc-Labeled Dimeric Folic Acid for FR-Targeting.
Topics: Animals; Cell Line, Tumor; Folate Receptor 1; Folic Acid; Humans; Mice; Neoplasms; Octreotide; Organophosphorus Compounds; Organotechnetium Compounds; Radiopharmaceuticals; Sulfonic Acids; Technetium; Tissue Distribution | 2016 |
Fabrication of folic acid-sensitive gold nanoclusters for turn-on fluorescent imaging of overexpression of folate receptor in tumor cells.
Topics: Biosensing Techniques; Fluorescent Dyes; Folate Receptor 2; Folic Acid; Gold; HeLa Cells; Humans; Metal Nanoparticles; Nanocomposites; Neoplasms; Serum Albumin, Bovine; Spectrometry, Fluorescence | 2016 |
Immobilization free electrochemical biosensor for folate receptor in cancer cells based on terminal protection.
Topics: Biosensing Techniques; DNA, Single-Stranded; Electrochemical Techniques; Electrodes; Exodeoxyribonucleases; Ferrous Compounds; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Limit of Detection; Metallocenes; Neoplasms; Reproducibility of Results; Tin Compounds | 2016 |
"Smart" nickel oxide based core-shell nanoparticles for combined chemo and photodynamic cancer therapy.
Topics: Antineoplastic Agents; Cell Death; Cell Survival; Doxorubicin; Drug Delivery Systems; Drug Liberation; Folic Acid; HeLa Cells; Humans; Microscopy, Fluorescence; Nanoparticles; Nanospheres; Neoplasms; Nickel; Photochemotherapy; Reactive Oxygen Species; Serum Albumin, Bovine | 2016 |
Microfluidic synthesis of multifunctional liposomes for tumour targeting.
Topics: Animals; Cell Line; Cell Line, Tumor; Drug Delivery Systems; Endocytosis; Flow Cytometry; Folic Acid; Humans; Liposomes; Macrophages; MCF-7 Cells; Mice; Microfluidics; Microscopy, Confocal; Microscopy, Electron, Transmission; Neoplasms; Phosphatidylethanolamines; Polyethylene Glycols; Spheroids, Cellular; Surface Properties | 2016 |
Targeted Raman Imaging of Cells Using Graphene Oxide-Based Hybrids.
Topics: Cell Line, Tumor; Folate Receptors, GPI-Anchored; Folic Acid; Gold; Graphite; Humans; Metal Nanoparticles; Neoplasms; Oxides; Spectrum Analysis, Raman; Thioglycolates | 2016 |
Paclitaxel loaded magnetic nanocomposites with folate modified chitosan/carboxymethyl surface; a vehicle for imaging and targeted drug delivery.
Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Chitosan; Drug Delivery Systems; Drug Liberation; Erythrocytes; Ferric Compounds; Folic Acid; Hemolysis; Humans; Magnetic Phenomena; MCF-7 Cells; Nanocomposites; Neoplasms; Nickel; Paclitaxel; Serum Albumin, Bovine | 2016 |
Targeted Tumor Therapy Based on Nanodiamonds Decorated with Doxorubicin and Folic Acid.
Topics: Animals; Cell Line, Tumor; Cell Survival; Doxorubicin; Endocytosis; Folic Acid; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Molecular Targeted Therapy; Nanodiamonds; Neoplasms; Particle Size; Static Electricity | 2017 |
Folate-decorated arginine-based poly(ester urea urethane) nanoparticles as carriers for gambogic acid and effect on cancer cells.
Topics: A549 Cells; Drug Carriers; Folic Acid; HeLa Cells; Humans; Nanoparticles; Neoplasms; Polyesters; Xanthones | 2017 |
Folic acid conjugates with photosensitizers for cancer targeting in photodynamic therapy: Synthesis and photophysical properties.
Topics: Chemistry Techniques, Synthetic; Chlorophyllides; Diethylamines; Folic Acid; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents; Porphyrins | 2017 |
Superparamagnetic iron oxide nanoparticles conjugated with folic acid for dual target-specific drug delivery and MRI in cancer theranostics.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Proliferation; Cell Survival; Dextrans; Doxorubicin; Drug Delivery Systems; Female; Folic Acid; Humans; Hydrodynamics; Hydrogen-Ion Concentration; Magnetic Resonance Imaging; Magnetite Nanoparticles; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Particle Size; Surface Properties; Theranostic Nanomedicine; Tissue Distribution | 2017 |
Immune activity and biodistribution of polypeptide K237 and folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles radiolabeled with 99mTc.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Folic Acid; Humans; Isotope Labeling; Male; Mice; Nanoparticles; Neoplasms; Oligopeptides; Organotechnetium Compounds; Polyethylene Glycols; Polyglactin 910; Tissue Distribution; Xenograft Model Antitumor Assays | 2016 |
Fabrication and bioconjugation of B
Topics: Animals; Folic Acid; HEK293 Cells; Humans; Hyaluronic Acid; Luminescence; MCF-7 Cells; Metal Nanoparticles; Mice, Inbred BALB C; Mice, Nude; Nanoconjugates; Neoplasms | 2016 |
Supramolecular cyclodextrin nanocarriers for chemo- and gene therapy towards the effective treatment of drug resistant cancers.
Topics: Animals; Cyclodextrins; Drug Delivery Systems; Drug Resistance, Neoplasm; Folic Acid; Genetic Therapy; HeLa Cells; Hep G2 Cells; Humans; Mice; Molecular Structure; Nanoparticles; Neoplasms; Nuclear Receptor Subfamily 4, Group A, Member 1; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Transfection; Xenograft Model Antitumor Assays | 2016 |
Low-dose methotrexate enhances cycling of highly anaplastic cancer cells.
Topics: Amino Acids; Animals; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; Folic Acid; Male; Metabolic Networks and Pathways; Methotrexate; Neoplasms; Rats, Wistar | 2017 |
Design and construction of multifunctional hyperbranched polymers coated magnetite nanoparticles for both targeting magnetic resonance imaging and cancer therapy.
Topics: Antioxidants; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Neoplasms; Polyethylene Glycols; Polymerization; Quercetin | 2017 |
Multi-Functional Nanogels for Tumor Targeting and Redox-Sensitive Drug and siRNA Delivery.
Topics: Animals; Antioxidants; Cell Line, Tumor; Doxorubicin; Folic Acid; Folic Acid Transporters; HeLa Cells; Humans; Mice; Nanogels; Nanoparticles; Neoplasms; NIH 3T3 Cells; Oxidation-Reduction; Particle Size; Polyethylene Glycols; Polyethyleneimine; Povidone; RNA, Small Interfering | 2016 |
Folic acid-grafted bovine serum albumin decorated graphene oxide: An efficient drug carrier for targeted cancer therapy.
Topics: Animals; Antibiotics, Antineoplastic; Cattle; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Graphite; Hemolysis; Humans; Neoplasms; Oxides; Rabbits; Serum Albumin, Bovine | 2017 |
Folate-Hapten-Mediated Immunotherapy Synergizes with Vascular Endothelial Growth Factor Receptor Inhibitors in Treating Murine Models of Cancer.
Topics: Animals; Antineoplastic Agents; Axitinib; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Female; Folic Acid; Haptens; Humans; Imidazoles; Immunotherapy; Indazoles; Mice; Neoplasms; Neovascularization, Pathologic; Protein Kinase Inhibitors; Receptors, Vascular Endothelial Growth Factor; T-Lymphocyte Subsets; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Magnetic and Folate Functionalization Enables Rapid Isolation and Enhanced Tumor-Targeting of Cell-Derived Microvesicles.
Topics: Antibiotics, Antineoplastic; Cell Proliferation; Cell-Derived Microparticles; Doxorubicin; Folic Acid; HeLa Cells; Humans; Magnetic Fields; Magnetite Nanoparticles; Neoplasms; Streptavidin | 2017 |
Erythrocyte Membrane-Coated Upconversion Nanoparticles with Minimal Protein Adsorption for Enhanced Tumor Imaging.
Topics: Adsorption; Erythrocyte Membrane; Folic Acid; Humans; Nanoparticles; Neoplasms | 2017 |
Rapidly cell-penetrating and reductive milieu-responsive nanoaggregates assembled from an amphiphilic folate-camptothecin prodrug for enhanced drug delivery and controlled release.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Delayed-Action Preparations; Drug Delivery Systems; Folic Acid; Glutathione; Humans; Neoplasms; Prodrugs | 2017 |
One-step synthesis of photoluminescent carbon dots with excitation-independent emission for selective bioimaging and gene delivery.
Topics: Carbon; Cell Survival; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Therapy; HEK293 Cells; HeLa Cells; Humans; Neoplasms; Optical Imaging; Particle Size; Polyethyleneimine; Quantum Dots; Surface Properties; Transfection | 2017 |
Boronic Acid vs. Folic Acid: A Comparison of the bio-recognition performances by Impedimetric Cytosensors based on Ferrocene cored dendrimer.
Topics: Biosensing Techniques; Cell Line, Tumor; Dendrimers; Dielectric Spectroscopy; Electrodes; Equipment Design; Ferrous Compounds; Folic Acid; Gold; HEK293 Cells; Humans; Metallocenes; Neoplasms; Reproducibility of Results | 2017 |
Diagnosis-Therapy Integrative Systems Based on Magnetic RNA Nanoflowers for Co-drug Delivery and Targeted Therapy.
Topics: Animals; Antineoplastic Agents; Cell Survival; Doxorubicin; Drug Carriers; Flow Cytometry; Folic Acid; HeLa Cells; Humans; Light; Magnetics; Mice; Nanoparticles; Neoplasms; Optical Imaging; Photosensitizing Agents; Porphyrins; RNA | 2017 |
Kinetic limitations of cooperativity-based drug delivery systems.
Topics: Adsorption; Antineoplastic Agents; Carrier Proteins; Dendrimers; DNA, Single-Stranded; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Models, Biological; Models, Chemical; Nanostructures; Neoplasm Proteins; Neoplasms; Polyamines; Receptors, Cell Surface; Thermodynamics | 2008 |
Improvement of meta-tetra(hydroxyphenyl)chlorin-like photosensitizer selectivity with folate-based targeted delivery. synthesis and in vivo delivery studies.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Drug Delivery Systems; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation; Humans; Mesoporphyrins; Mice; Mice, Nude; Molecular Structure; Neoplasms; Photochemistry; Photosensitizing Agents; Receptors, Cell Surface; Spectrophotometry; Xenograft Model Antitumor Assays | 2008 |
Mathematical modeling of folate metabolism: predicted effects of genetic polymorphisms on mechanisms and biomarkers relevant to carcinogenesis.
Topics: Biomarkers, Tumor; DNA Methylation; DNA, Neoplasm; Folic Acid; Genotype; Humans; Models, Theoretical; Neoplasms; Polymorphism, Genetic; Reproducibility of Results | 2008 |
Functionalized amphiphilic hyperbranched polymers for targeted drug delivery.
Topics: Antineoplastic Agents; Chromatography; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Nanoparticles; Neoplasms; Polyethylene Glycols; Polymers; Scattering, Radiation | 2008 |
Polymeric micelles modified by folate-PEG-lipid for targeted drug delivery to cancer cells in vitro.
Topics: Cell Line; Flow Cytometry; Folic Acid; Humans; In Vitro Techniques; Lipids; Micelles; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasms; Polyethylene Glycols; Polymers | 2008 |
Impact of high and low folate diets on tissue folate receptor levels and antitumor responses toward folate-drug conjugates.
Topics: Animals; Carrier Proteins; Diet; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Mice; Neoplasms; Receptors, Cell Surface; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2008 |
Molecular mechanisms of adaptation to folate deficiency.
Topics: Animals; Antineoplastic Agents; Atherosclerosis; Carrier Proteins; Drug Resistance, Neoplasm; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Heart Defects, Congenital; Humans; Hyperhomocysteinemia; Mice; Neoplasms; Neural Tube Defects | 2008 |
DNA nanotubes as combinatorial vehicles for cellular delivery.
Topics: Cell Line; DNA, Single-Stranded; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Microscopy, Confocal; Nanotubes; Neoplasms | 2008 |
Teropterin, pteroyl-triglutamic acid in human cancers; preliminary report.
Topics: Folic Acid; Humans; Neoplasms; Pteroylpolyglutamic Acids | 1948 |
Folic acid derivatives and their suitability as cancer medicines.
Topics: Antimetabolites; Folic Acid; Humans; Neoplasms | 1948 |
Anticancer action of some folic acid derivatives.
Topics: Folic Acid; Humans; Neoplasms | 1948 |
Effect of folic acid and bis (beta-chloroethyl) sulfide (mustard gas) on transplanted mouse lymphosarcoma.
Topics: Folic Acid; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mustard Gas; Neoplasms; Sarcoma; Sulfides | 1947 |
Folate and folate-PEG-PAMAM dendrimers: synthesis, characterization, and targeted anticancer drug delivery potential in tumor bearing mice.
Topics: Animals; Antineoplastic Agents; Dendrimers; Drug Carriers; Female; Fluorouracil; Folic Acid; Hemolysis; Mice; Mice, Inbred BALB C; Neoplasms; Polyamines; Polyethylene Glycols; Succinimides; Tissue Distribution | 2008 |
Selective delivery of folate-PEG-linked, nanoemulsion-loaded aclacinomycin A to KB nasopharyngeal cells and xenograft: effect of chain length and amount of folate-PEG linker.
Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Folic Acid; Humans; Mice; Mice, Nude; Nanostructures; Nasopharynx; Neoplasms; Polyethylene Glycols; Specific Pathogen-Free Organisms; Transplantation, Heterologous | 2008 |
Targeting and imaging cancer cells by folate-decorated, quantum dots (QDs)- loaded nanoparticles of biodegradable polymers.
Topics: Animals; Biocompatible Materials; Cell Death; Cell Line, Tumor; Cell Survival; Folic Acid; Humans; Mice; Microscopy, Confocal; Microscopy, Electron; Nanoparticles; Neoplasms; NIH 3T3 Cells; Particle Size; Polyethylene Glycols; Quantum Dots; Spectrum Analysis; Static Electricity; Succinates; Surface Properties; Vitamin E | 2009 |
Vitamin supplements and cancer prevention: where do randomized controlled trials stand?
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Colorectal Neoplasms; Confounding Factors, Epidemiologic; Dietary Supplements; Female; Folic Acid; Humans; Incidence; Lung Neoplasms; Male; Neoplasms; Primary Prevention; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Risk Assessment; Selenium; United States; Vitamin B 12; Vitamin B 6; Vitamin E | 2009 |
9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: preparation and evaluation in vitro.
Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Drug Evaluation, Preclinical; Folic Acid; HeLa Cells; Humans; Micelles; Neoplasms; Polymers | 2009 |
Evaluation of a novel radiofolate in tumour-bearing mice: promising prospects for folate-based radionuclide therapy.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Female; Folate Receptors, GPI-Anchored; Folic Acid; Heterocyclic Compounds, 1-Ring; Humans; Mice; Neoplasms; Radiopharmaceuticals; Receptors, Cell Surface; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2009 |
Colon cancer in Chile before and after the start of the flour fortification program with folic acid.
Topics: Aged; Cardiovascular Diseases; Chile; Colonic Neoplasms; Female; Flour; Folic Acid; Food, Fortified; Humans; Middle Aged; Neoplasms; Patient Discharge | 2009 |
Targeting of porous hybrid silica nanoparticles to cancer cells.
Topics: Carrier Proteins; Coculture Techniques; Drug Delivery Systems; Flow Cytometry; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Microscopy, Fluorescence; Nanoparticles; Nanotechnology; Neoplasms; Polyethyleneimine; Polymers; Porosity; Receptors, Cell Surface; Silicon Dioxide | 2009 |
Cellular folate status modulates the expression of BCRP and MRP multidrug transporters in cancer cell lines from different origins.
Topics: Adaptation, Physiological; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Genes, MDR; Humans; Membrane Transport Proteins; Mitoxantrone; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms; Peptide Synthases; Tetrahydrofolate Dehydrogenase; Tissue Distribution | 2009 |
Nutrients for prevention: negative trials send researchers back to drawing board.
Topics: beta Carotene; Calcium; Clinical Trials as Topic; Folic Acid; Food-Drug Interactions; Humans; Micronutrients; Neoplasms; Research Design; Selenium; Trace Elements; Treatment Failure; Vitamin B 12; Vitamin B 6; Vitamin D; Vitamin E; Vitamins | 2009 |
Acculturation and serum nutrients thought to be involved with cancer prevention among Mexican American men in the United States.
Topics: Acculturation; Adolescent; Adult; Aged; Aged, 80 and over; Ascorbic Acid; Carotenoids; Diet; Folic Acid; Food; Humans; Lycopene; Male; Mexican Americans; Micronutrients; Middle Aged; Neoplasms; Risk Factors; Selenium; United States; Vitamin D; Vitamin E | 2009 |
Drug/dye-loaded, multifunctional iron oxide nanoparticles for combined targeted cancer therapy and dual optical/magnetic resonance imaging.
Topics: Antineoplastic Agents; Diffusion; Drug Delivery Systems; Ferric Compounds; Fluorescent Dyes; Folic Acid; Humans; Ligands; Magnetic Resonance Imaging; Magnetics; Metal Nanoparticles; Nanotechnology; Neoplasms; Optics and Photonics; Solvents; Spectrophotometry, Infrared | 2009 |
Serum folate and cancer mortality among U.S. adults: findings from the Third National Health and Nutritional Examination Survey linked mortality file.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Death Certificates; Female; Folic Acid; Humans; Male; Neoplasms; Nutrition Surveys; Proportional Hazards Models; Prospective Studies; Risk Factors; United States | 2009 |
Targeted delivery and controlled release of doxorubicin to cancer cells using modified single wall carbon nanotubes.
Topics: Biocompatible Materials; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Materials Testing; Nanotechnology; Nanotubes, Carbon; Neoplasms; Polysaccharides | 2009 |
Gold nanoparticles with a monolayer of doxorubicin-conjugated amphiphilic block copolymer for tumor-targeted drug delivery.
Topics: Animals; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Endocytosis; Folic Acid; Gold; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Metal Nanoparticles; Mice; Micelles; Nanotechnology; Neoplasms; NIH 3T3 Cells; Polymers | 2009 |
Folate-conjugated micelles and their folate-receptor-mediated endocytosis.
Topics: Animals; Biocompatible Materials; Carrier Proteins; CHO Cells; Cricetinae; Cricetulus; Drug Carriers; Drug Delivery Systems; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Materials Testing; Mice; Micelles; Molecular Structure; Neoplasms; Polymers; Receptors, Cell Surface; Vitamin B Complex | 2009 |
Improved therapeutic activity of folate-targeted liposomal doxorubicin in folate receptor-expressing tumor models.
Topics: Animals; Antibiotics, Antineoplastic; Carrier Proteins; Cell Line, Transformed; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Delivery Systems; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Injections, Intraperitoneal; Injections, Intravenous; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Polyethylene Glycols; Receptors, Cell Surface; Xenograft Model Antitumor Assays | 2010 |
Ligand-targeted delivery of small interfering RNAs to malignant cells and tissues.
Topics: Animals; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Glutarates; HeLa Cells; Humans; Ligands; Male; Mice; Mice, Mutant Strains; Neoplasms; Receptors, Cell Surface; RNA, Small Interfering; Urea; Xenograft Model Antitumor Assays | 2009 |
Ring-opening metathesis polymerization-based synthesis of polymeric nanoparticles for enhanced tumor imaging in vivo: Synergistic effect of folate-receptor targeting and PEGylation.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Contrast Media; Drug Carriers; Folate Receptors, GPI-Anchored; Folic Acid; Image Enhancement; Materials Testing; Mice; Mice, Nude; Microscopy, Fluorescence; Molecular Probe Techniques; Nanoparticles; Neoplasms; Polyethylene Glycols; Polymers; Receptors, Cell Surface | 2010 |
UK food agency reaffirms its advice that addition of folic acid to flour should be compulsory.
Topics: Flour; Folic Acid; Food Additives; Humans; Legislation, Food; Neoplasms; United Kingdom | 2009 |
The targeting behavior of folate-nanohydrogel evaluated by near infrared imaging system in tumor-bearing mouse model.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Hydrogels; Mice; Mice, Nude; Nanotechnology; Neoplasms; Particle Size; Tissue Distribution; Xenograft Model Antitumor Assays | 2010 |
Cancer incidence and mortality after treatment with folic acid and vitamin B12.
Topics: Aged; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Humans; Male; Middle Aged; Mortality; Myocardial Ischemia; Neoplasms; Norway; Proportional Hazards Models; Randomized Controlled Trials as Topic; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2009 |
Assessing cancer prevention studies--a matter of time.
Topics: Dietary Supplements; Folic Acid; Humans; Neoplasms; Risk Assessment; Time Factors; Vitamin B 12; Vitamin B Complex | 2009 |
Gadolinium-conjugated dendrimer nanoclusters as a tumor-targeted T1 magnetic resonance imaging contrast agent.
Topics: Animals; Contrast Media; Cross-Linking Reagents; Dendrimers; Electron Spin Resonance Spectroscopy; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Folic Acid; Gadolinium; Gadolinium DTPA; Humans; KB Cells; Magnetic Resonance Imaging; Mice; Microscopy, Electron, Transmission; Nanoparticles; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental | 2010 |
A specific tumor-targeting magnetofluorescent nanoprobe for dual-modality molecular imaging.
Topics: Acrylic Resins; Cell Death; Cell Line; Cell Survival; Elements; Ferric Compounds; Flow Cytometry; Fluorescent Dyes; Folic Acid; Humans; Magnetic Resonance Spectroscopy; Magnetics; Microscopy, Confocal; Molecular Imaging; Nanostructures; Neoplasms; Organ Specificity; Phantoms, Imaging; Polyethylene Glycols; Rhodamine 123; Temperature | 2010 |
The therapeutic efficiency of FP-PEA/TAM67 gene complexes via folate receptor-mediated endocytosis in a xenograft mice model.
Topics: Animals; Carrier Proteins; Drug Carriers; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Gene Transfer Techniques; Humans; Male; Materials Testing; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Neoplasms; Peptide Fragments; Polyamines; Polyesters; Polyethyleneimine; Proto-Oncogene Proteins c-jun; Receptors, Cell Surface; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2010 |
A molecular receptor targeted, hydroxyapatite nanocrystal based multi-modal contrast agent.
Topics: Animals; Carrier Proteins; Cell Line; Contrast Media; Crystallography, X-Ray; Durapatite; Endothelial Cells; Flow Cytometry; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Infrared Rays; Magnetic Resonance Spectroscopy; Magnetics; Mice; Microscopy, Fluorescence; Molecular Imaging; Nanoparticles; Neoplasms; Particle Size; Polyethyleneimine; Receptors, Cell Surface; Spectrometry, Fluorescence; Umbilical Veins; Vibration | 2010 |
Graft and diblock copolymer multifunctional micelles for cancer chemotherapy and imaging.
Topics: Animals; Antibiotics, Antineoplastic; Biocompatible Materials; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Mice; Micelles; Molecular Structure; Neoplasm Transplantation; Neoplasms; Polymers; Tissue Distribution | 2010 |
Radiosynthesis and micro-SPECT imaging of 99mTc-dendrimer poly(amido)-amine folic acid conjugate.
Topics: Animals; Dendrimers; Folic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Polyamines; Radioisotopes; Technetium; Tomography, Emission-Computed, Single-Photon | 2010 |
Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2.
Topics: Antimetabolites, Antineoplastic; Antioxidants; Base Sequence; Cell Line, Tumor; DNA Damage; DNA Mismatch Repair; Folic Acid; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Methotrexate; Molecular Sequence Data; MutS Homolog 2 Protein; Neoplasms; Oxidation-Reduction; RNA, Antisense | 2009 |
Rational design of targeted cancer therapeutics through the multiconjugation of folate and cleavable siRNA to RAFT-synthesized (HPMA-s-APMA) copolymers.
Topics: Acrylamides; Acrylic Resins; Antineoplastic Agents; Drug Delivery Systems; Drug Design; Folic Acid; Humans; Neoplasms; Organometallic Compounds; RNA, Small Interfering | 2010 |
Folate-PEG coated cationic modified chitosan--cholesterol liposomes for tumor-targeted drug delivery.
Topics: Cations; Cell Line, Tumor; Chitosan; Cholesterol; Drug Delivery Systems; Flow Cytometry; Fluoresceins; Folic Acid; Humans; Hydrogen-Ion Concentration; Kinetics; Liposomes; Magnetic Resonance Spectroscopy; Micelles; Microscopy, Fluorescence; Neoplasms; Particle Size; Permeability; Polyethylene Glycols; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Time Factors | 2010 |
Gold nanorods: multifunctional agents for cancer imaging and therapy.
Topics: Animals; Diagnostic Imaging; Folic Acid; Gold; Mice; Nanomedicine; Nanotubes; Neoplasms; Polyethylene Glycols; Surface Properties | 2010 |
Targeting of nanoparticles: folate receptor.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Diagnostic Imaging; Drug Delivery Systems; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Mice; Mice, Nude; Nanomedicine; Nanoparticles; Neoplasms; Phosphatidylethanolamines; Polyethylene Glycols; Pterins; Receptors, Cell Surface | 2010 |
Vitamin B complex, menorrhagia, and cancer; a critical review.
Topics: Female; Folic Acid; Humans; Menorrhagia; Neoplasms; Vitamin B Complex; Vitamins | 1947 |
Folic acid (pteroylglutamic acid) studies; hematologic remissions in pernicious anemia.
Topics: Anemia; Anemia, Pernicious; Folic Acid; Neoplasms; Tracheophyta; Vitamin B Complex; Vitamins | 1947 |
Folate-polyethylene glycol conjugated near-infrared fluorescence probe with high targeting affinity and sensitivity for in vivo early tumor diagnosis.
Topics: Animals; Drug Delivery Systems; Early Detection of Cancer; Female; Fluorescent Dyes; Folic Acid; HeLa Cells; Hep G2 Cells; Humans; Male; Mice; Mice, Nude; Models, Biological; Molecular Probes; Neoplasms; Polyethylene Glycols; Rats; Sensitivity and Specificity; Spectroscopy, Near-Infrared; Substrate Specificity; Tumor Cells, Cultured | 2010 |
Preliminary studies on the selective accumulation of vitamin-targeted polymers within tumors.
Topics: Acrylamides; Animals; Biotin; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Mice; Microscopy, Fluorescence; Neoplasms; Neoplasms, Experimental; Tissue Distribution; Vitamin B 12; Vitamins | 2011 |
Pediatric cancer rates after universal folic acid flour fortification in Ontario.
Topics: Child; Child, Preschool; Cohort Studies; Folic Acid; Food, Fortified; Humans; Infant; Kidney Neoplasms; Neoplasms; Ontario; Registries; Retrospective Studies; Wilms Tumor | 2011 |
Chemical modification of M13 bacteriophage and its application in cancer cell imaging.
Topics: Bacteriophage M13; Fluorescent Dyes; Folic Acid; HeLa Cells; Humans; Molecular Imaging; Molecular Structure; Neoplasms; Particle Size; Stereoisomerism; Surface Properties; Tumor Cells, Cultured | 2010 |
Anticancer vitamins du Jour--The ABCED's so far.
Topics: Animals; Ascorbic Acid; Folic Acid; Humans; Neoplasms; Randomized Controlled Trials as Topic; Riboflavin; Vitamin A; Vitamin D; Vitamin E; Vitamins | 2010 |
High-frequency, magnetic-field-responsive drug release from magnetic nanoparticle/organic hybrid based on hyperthermic effect.
Topics: Animals; Cell Line; Drug Carriers; Ferric Compounds; Folic Acid; Hematinics; Hot Temperature; Humans; Magnetics; Mice; Microglia; Nanoparticles; Neoplasms | 2010 |
Folate targeted polymeric 'green' nanotherapy for cancer.
Topics: Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Cell Shape; Flow Cytometry; Folate Receptors, GPI-Anchored; Folic Acid; Grape Seed Extract; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Particle Size; Phytotherapy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proanthocyanidins; Receptors, Cell Surface; Spectroscopy, Fourier Transform Infrared | 2010 |
Conjugating folic acid to gold nanoparticles through glutathione for targeting and detecting cancer cells.
Topics: Animals; Carrier Proteins; Cell Line; Folate Receptors, GPI-Anchored; Folic Acid; Glutathione; Gold; HeLa Cells; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Mice; Microscopy, Confocal; Neoplasms; Osmolar Concentration; Receptors, Cell Surface | 2010 |
Relevance of folic acid/polymer ratio in targeted PEG-epirubicin conjugates.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Epirubicin; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Polyethylene Glycols | 2010 |
Synthesis and grafting of folate-PEG-PAMAM conjugates onto quantum dots for selective targeting of folate-receptor-positive tumor cells.
Topics: Antineoplastic Agents; Cell Survival; Dendrimers; Diagnostic Imaging; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Models, Biological; Neoplasms; Polyethylene Glycols; Quantum Dots; Receptors, Cell Surface; Solubility; Water | 2010 |
Ionically crosslinked Ad/chitosan nanocomplexes processed by electrospinning for targeted cancer gene therapy.
Topics: Adenoviridae; Animals; Chitosan; Folic Acid; Gene Transfer Techniques; Genetic Therapy; Humans; Mice; Microscopy, Electron, Transmission; Neoplasms; Polyethylene Glycols | 2010 |
Dietary folate intake and the risk of 11 types of cancer: a case-control study in Uruguay.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasms; Surveys and Questionnaires; Uruguay | 2011 |
New Zealand should have mandatory fortification of bread with folic acid: yes.
Topics: Bread; Folic Acid; Food, Fortified; Humans; Neoplasms; Neural Tube Defects; New Zealand; Nutrition Policy; Risk | 2010 |
Triggering liposomal drug release with a lysosomotropic agent.
Topics: Animals; Antibiotics, Antineoplastic; Arylsulfonates; Cell Line, Tumor; Chloroquine; Daunorubicin; Female; Folic Acid; Humans; Hydrogen-Ion Concentration; Leukemia L1210; Liposomes; Lysosomes; Mice; Mice, Inbred DBA; Microscopy, Confocal; Neoplasms | 2010 |
Multifunctional SPIO/DOX-loaded wormlike polymer vesicles for cancer therapy and MR imaging.
Topics: Cell Death; Dextrans; Doxorubicin; Drug Carriers; Drug Delivery Systems; Flow Cytometry; Folic Acid; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetite Nanoparticles; Microscopy, Confocal; Nanoparticles; Neoplasms; Polymers | 2010 |
Solar radiation and human health.
Topics: Folic Acid; Humans; Neoplasms; Sunlight; Ultraviolet Rays; Vitamin D | 2010 |
Evaluation of folate conjugated pegylated thermosensitive magnetic nanocomposites for tumor imaging and therapy.
Topics: Animals; Cell Line; Cell Survival; Diagnostic Imaging; Doxorubicin; Fibroblasts; Folic Acid; Iron; Magnetics; Mice; Nanocomposites; Nanomedicine; Neoplasms; Particle Size; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared; Temperature; X-Ray Diffraction | 2011 |
Tamoxifen-loaded folate-conjugate poly[(p-nitrophenyl acrylate)-co-(N-isopropylacrylamide)] sub-microgel as antitumoral drug delivery system.
Topics: Acrylic Resins; Animals; Cell Line, Tumor; Drug Delivery Systems; Female; Folic Acid; Freeze Drying; Gels; Humans; Injections, Subcutaneous; Materials Testing; Microscopy, Electron, Scanning; Neoplasms; Rats; Rats, Wistar; Tamoxifen | 2010 |
A prospective, observational study describing the haematological response in patients undergoing chemotherapy treated by tri-weekly darbepoetin alfa for anaemia.
Topics: Aged; Anemia; Antineoplastic Agents; Cohort Studies; Darbepoetin alfa; Dietary Supplements; Erythropoietin; Female; Folic Acid; France; Hematinics; Humans; Iron; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Prospective Studies; Vitamin B 12 | 2010 |
The vital amines: too much of a good thing?: comment on "Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality".
Topics: Cardiovascular Diseases; Cause of Death; Folic Acid; Homocysteine; Humans; Neoplasms; Randomized Controlled Trials as Topic; Stroke; Vitamin B Complex | 2010 |
Targeted thiazole orange derivative with folate: synthesis, fluorescence and in vivo fluorescence imaging.
Topics: Animals; Benzothiazoles; Cell Line, Tumor; Female; Fluorescent Dyes; Folic Acid; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms; Quinolines; Spectrometry, Fluorescence | 2010 |
A new 18F-labeled folic acid derivative with improved properties for the PET imaging of folate receptor-positive tumors.
Topics: Animals; Biological Transport; Fluorine Radioisotopes; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Glutamates; Guanine; Humans; Hydrophobic and Hydrophilic Interactions; KB Cells; Kidney; Ligands; Mice; Neoplasms; Pemetrexed; Positron-Emission Tomography; Radiochemistry; Staining and Labeling; Substrate Specificity | 2010 |
Folic acid-conjugated core/shell ZnS:Mn/ZnS quantum dots as targeted probes for two photon fluorescence imaging of cancer cells.
Topics: Cell Line, Tumor; Fluorescent Dyes; Folic Acid; Humans; Magnesium; Microscopy, Confocal; Microscopy, Electron, Transmission; Neoplasms; Quantum Dots; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sulfides; X-Ray Diffraction; Zinc Compounds | 2011 |
Effects of folic acid plus vitamin B12 vs placebo in myocardial infarction survivors.
Topics: Colorectal Neoplasms; Folic Acid; Follow-Up Studies; Humans; Hyperhomocysteinemia; Myocardial Infarction; Neoplasms; North America; Risk; Vitamin B 12; Vitamin B Complex | 2010 |
ESTROGEN: vitamin B complex; cancer.
Topics: Estrogens; Folic Acid; Humans; Neoplasms; Vitamin B Complex; Vitamins | 1946 |
Non-covalent association of folate to lipoplexes: a promising strategy to improve gene delivery in the presence of serum.
Topics: Animals; Cell Line, Tumor; DNA; Folic Acid; Gene Expression; Genetic Therapy; Green Fluorescent Proteins; Humans; Liposomes; Mice; Neoplasms; Serum; Static Electricity; Transfection | 2011 |
Multifunctional superparamagnetic nanocarriers with folate-mediated and pH-responsive targeting properties for anticancer drug delivery.
Topics: Antineoplastic Agents; Cell Death; Cell Proliferation; Cell Survival; Doxorubicin; Drug Carriers; Drug Delivery Systems; Ferric Compounds; Flow Cytometry; Fluorescence; Folic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Magnetics; Microscopy, Confocal; Nanoparticles; Neoplasms; Polymers; Time Factors | 2011 |
Cancer targeting potential of some ligand-anchored poly(propylene imine) dendrimers: a comparison.
Topics: Biological Assay; Cell Death; Cell Survival; Dendrimers; Dextrans; Flow Cytometry; Folic Acid; Galactose; HeLa Cells; Hemolysis; Humans; Ligands; Neoplasms; Organ Specificity; Paclitaxel; Polypropylenes | 2011 |
Synthesis and in vitro cancer cell targeting of folate-functionalized biodegradable amphiphilic dendrimer-like star polymers.
Topics: Carboxylic Acids; Cell Line, Tumor; Dendrimers; Drug Delivery Systems; Folic Acid; Humans; Lactic Acid; Micelles; Molecular Structure; Nanoparticles; Neoplasms; Polyesters; Polymers; Surface-Active Agents | 2010 |
Tumor selectivity of stealth multi-functionalized superparamagnetic iron oxide nanoparticles.
Topics: Animals; Cell Line, Tumor; Chitosan; Contrast Media; Dextrans; Drug Carriers; Folic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Light; Macrophages; Magnetic Resonance Imaging; Magnetics; Magnetite Nanoparticles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Mononuclear Phagocyte System; Nanotechnology; Neoplasms; Particle Size; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Surface Properties; Technology, Pharmaceutical; X-Ray Diffraction | 2011 |
(Coixan polysaccharide)-graft-polyethylenimine folate for tumor-targeted gene delivery.
Topics: Animals; Cell Death; Cell Line, Tumor; DNA; Electrophoretic Mobility Shift Assay; Folic Acid; Gene Transfer Techniques; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Neoplasms; Photoelectron Spectroscopy; Plasmids; Polyethyleneimine; Polysaccharides; Rats; Spectrophotometry, Ultraviolet; Transfection | 2011 |
Folic acid conjugates for nuclear imaging of folate receptor-positive cancer.
Topics: Folate Receptors, GPI-Anchored; Folic Acid; Humans; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2011 |
Multifunctional nanobeads based on quantum dots and magnetic nanoparticles: synthesis and cancer cell targeting and sorting.
Topics: Biological Transport; Cell Separation; Ethylamines; Fluorescent Dyes; Folic Acid; Humans; KB Cells; Magnetics; Microscopy, Confocal; Neoplasms; Quantum Dots; Spectrometry, Fluorescence; Surface Properties | 2011 |
In search of the Holy Grail: Folate-targeted nanoparticles for cancer therapy.
Topics: Antineoplastic Agents; Drug Carriers; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Nanoparticles; Neoplasms; Protein Binding | 2011 |
Encapsulation of 2-methoxyestradiol within multifunctional poly(amidoamine) dendrimers for targeted cancer therapy.
Topics: 2-Methoxyestradiol; Cell Line, Tumor; Cell Survival; Dendrimers; Estradiol; Fluorescein-5-isothiocyanate; Folic Acid; Humans; Kinetics; Magnetic Resonance Spectroscopy; Microscopy, Confocal; Neoplasms; Organ Specificity; Spectrophotometry, Ultraviolet; Static Electricity | 2011 |
Selective and quantitative cancer cell detection using target-directed functionalized graphene and its synergetic peroxidase-like activity.
Topics: Biocatalysis; Biomimetic Materials; Color; Colorimetry; Folic Acid; Graphite; HeLa Cells; Hemin; Humans; Neoplasms; Peroxidase | 2011 |
In vitro and in vivo evaluation of (99m)Tc-DO3A-EA-Folate for receptor-mediated targeting of folate positive tumors.
Topics: Animals; Cell Line, Tumor; Cell Membrane; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Organotechnetium Compounds; Rabbits; Radiopharmaceuticals; Spectrum Analysis; Tissue Distribution | 2011 |
Serum folate is significantly correlated with plasma cysteine concentrations in healthy industry workers.
Topics: Adult; Aged; Aging; Cardiovascular Diseases; Cysteine; Extraction and Processing Industry; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Norway; Risk Factors; Triglycerides; Young Adult | 2011 |
Anti-tumor efficacy of polymer-platinum(II) complex micelles fabricated from folate conjugated PEG-graft-α,β-poly [(N-amino acidyl)-aspartamide] and cis-dichlorodiammine platinum(II) in tumor-bearing mice.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Carriers; Drug Compounding; Folic Acid; Humans; Male; Mice; Mice, Nude; Micelles; Microscopy, Electron, Transmission; Neoplasms; Particle Size; Peptides; Polyethylene Glycols; Polymers; Xenograft Model Antitumor Assays | 2011 |
Quantum dot-folic acid conjugates as potential photosensitizers in photodynamic therapy of cancer.
Topics: Cadmium Compounds; Cell Line; Folate Receptor 1; Folic Acid; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents; Quantum Dots; Tellurium | 2011 |
Tumor targeted adenovirus nanocomplex ionically crosslinked by chitosan.
Topics: Adenoviridae; Chitosan; Folic Acid; Genetic Therapy; Humans; Nanostructures; Neoplasms; Polyethylene Glycols; Transduction, Genetic | 2010 |
Novel folate-hydroxamate based antimetabolites: synthesis and biological evaluation.
Topics: Antimetabolites; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonists; HeLa Cells; Histone Deacetylases; Humans; Hydroxamic Acids; Male; Methotrexate; Molecular Targeted Therapy; Neoplasms; Repressor Proteins; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2011 |
Amphiphilic multiarm star block copolymer-based multifunctional unimolecular micelles for cancer targeted drug delivery and MR imaging.
Topics: Animals; Cell Death; Cell Survival; Drug Delivery Systems; Folic Acid; Gadolinium; HeLa Cells; Humans; Hydrodynamics; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methacrylates; Micelles; Microscopy, Atomic Force; Neoplasms; Organ Specificity; Paclitaxel; Polyethylene Glycols; Polymers; Rats; Rats, Sprague-Dawley; Surface-Active Agents; Time Factors | 2011 |
Folate receptor-targeted aggregation-enhanced near-IR emitting silica nanoprobe for one-photon in vivo and two-photon ex vivo fluorescence bioimaging.
Topics: Animals; Female; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Mice; Mice, Nude; Microscopy, Fluorescence, Multiphoton; Nanoparticles; Neoplasms; Pyrans; Silicon Dioxide | 2011 |
PEG-templated mesoporous silica nanoparticles exclusively target cancer cells.
Topics: Animals; Antineoplastic Agents; Caveolin 1; Cell Line, Tumor; Cisplatin; Clathrin; Drug Carriers; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Folic Acid; Folic Acid Transporters; HEK293 Cells; HeLa Cells; Humans; Mice; Microscopy, Electron, Transmission; Models, Biological; Nanoparticles; Neoplasms; Particle Size; Polyethylene Glycols; Silicon Dioxide; Surface-Active Agents | 2011 |
A folate receptor-targeting nanoparticle minimizes drug resistance in a human cancer model.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Biological Transport; Cell Proliferation; Cell Survival; Drug Carriers; Drug Resistance, Neoplasm; Female; Folic Acid; Folic Acid Transporters; Heparin; Humans; KB Cells; Mice; Microtubules; Nanoparticles; Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays | 2011 |
Mathematical modeling predicts the effect of folate deficiency and excess on cancer-related biomarkers.
Topics: Biomarkers, Tumor; Folic Acid; Folic Acid Deficiency; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Neoplasms; Polymorphism, Genetic; Thymidylate Synthase | 2011 |
Application of the BRAFO tiered approach for benefit-risk assessment to case studies on dietary interventions.
Topics: Bread; Caloric Restriction; Cardiovascular Diseases; Chlorine; Diet; Dietary Carbohydrates; Dietary Fats; Drinking Water; Energy Intake; Europe; Fatty Acids, Monounsaturated; Female; Folic Acid; Food, Fortified; Health Promotion; Humans; Neoplasms; Pregnancy; Risk Assessment; Sweetening Agents; Weight Loss | 2012 |
Biomimetic nanocrystalline apatites: Emerging perspectives in cancer diagnosis and treatment.
Topics: Apatites; Biological Availability; Biomimetic Materials; Calcium Compounds; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Diagnostic Imaging; Drug Delivery Systems; Endocytosis; Erythrosine; Europium; Folic Acid; Humans; Luminescent Measurements; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Microspheres; Monocytes; Nanoparticles; Neoplasms; Nitrates; Organophosphates; Particle Size; Pectins; Phosphates; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Static Electricity; Water; X-Ray Diffraction | 2012 |
Synthesis and biological evaluation of receptor-based tumor imaging agent: (99m)Tc-folate-glucaric acid.
Topics: Animals; Drug Stability; Female; Folate Receptors, GPI-Anchored; Folic Acid; Isotope Labeling; Neoplasms; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Solubility; Tissue Distribution | 2011 |
Improved tumor targeting of polymer-based nanovesicles using polymer-lipid blends.
Topics: Animals; Butadienes; Cell Line, Tumor; Drug Delivery Systems; Elastomers; Female; Folic Acid; Humans; Mice; Mice, SCID; Nanocapsules; Neoplasms; NIH 3T3 Cells; Phosphatidylcholines; Polyethylene Glycols; Receptor, ErbB-2 | 2011 |
Cell-specific, activatable, and theranostic prodrug for dual-targeted cancer imaging and therapy.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Doxorubicin; Drug Design; Drug Screening Assays, Antitumor; Fluorescence; Folic Acid; Humans; Neoplasms; Prodrugs; Structure-Activity Relationship | 2011 |
Synthesis of novel folate conjugated fluorescent nanoparticles for tumor imaging.
Topics: Animals; Cell Transplantation; Diagnostic Imaging; Folate Receptors, GPI-Anchored; Folic Acid; HeLa Cells; Humans; Materials Testing; Mice; Mice, Nude; Molecular Structure; Nanoparticles; Neoplasms; Particle Size; Styrenes | 2011 |
Selective N-alkylation of β-alanine facilitates the synthesis of a poly(amino acid)-based theranostic nanoagent.
Topics: Alkylation; Antineoplastic Agents, Phytogenic; beta-Alanine; Biopolymers; Cell Line, Tumor; Fluorescent Dyes; Folic Acid; Folic Acid Transporters; Humans; Hydrophobic and Hydrophilic Interactions; Light; Molecular Weight; Nanocapsules; Neoplasms; Paclitaxel; Particle Size; Peptides; Scattering, Radiation | 2011 |
Fluorescent magnetic nanoparticles with specific targeting functions for combinded targeting, optical imaging and magnetic resonance imaging.
Topics: Animals; Cell Line, Tumor; Contrast Media; Ferric Compounds; Fluorescence; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice, Nude; Neoplasm Transplantation; Neoplasms; Optical Imaging; Particle Size; Phantoms, Imaging; Polyethylene Glycols; Silanes | 2012 |
Influence of side chain length on fluorescence intensity of ROMP-based polymeric nanoparticles and their tumor specificity in in-vivo tumor imaging.
Topics: Animals; Diagnostic Imaging; Fluorescence; Fluorescent Dyes; Folic Acid; Glucosamine; Mice; Nanoparticles; Neoplasms; Oligopeptides; Polymerization; Polymers | 2011 |
Comparison of standardised dietary folate intake across ten countries participating in the European Prospective Investigation into Cancer and Nutrition.
Topics: Adult; Aged; Cohort Studies; Cross-Sectional Studies; Diet; Diet Surveys; Europe; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasms; Seasons | 2012 |
Folic acid modified gelatine coated quantum dots as potential reagents for in vitro cancer diagnostics.
Topics: Caco-2 Cells; Cadmium Compounds; Folate Receptors, GPI-Anchored; Folic Acid; Gelatin; Humans; Microscopy, Confocal; Nanocomposites; Neoplasms; Quantum Dots; Tellurium | 2011 |
Photodynamic anticancer activities of water-soluble C(60) derivatives and their biological consequences in a HeLa cell line.
Topics: Antineoplastic Agents; Apoptosis; Arginine; Caspase 3; Catalase; Cell Survival; Folic Acid; Fullerenes; Glutathione Peroxidase; HeLa Cells; Humans; Light; Malondialdehyde; Membrane Potential, Mitochondrial; Neoplasms; Phenylalanine; Photochemotherapy; Reactive Oxygen Species; Superoxide Dismutase; Water | 2012 |
In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin).
Topics: Anticarcinogenic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Folate Receptor 1; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Ligands; Microtubules; Models, Molecular; Neoplasms; Noscapine; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tubulin | 2012 |
Magnetic nanocarriers of doxorubicin coated with poly(ethylene glycol) and folic acid: relation between coating structure, surface properties, colloidal stability, and cancer cell targeting.
Topics: Colloids; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Magnetics; Microscopy, Electron, Transmission; Nanoparticles; Neoplasms; Polyethylene Glycols; Spectrophotometry, Atomic; Spectroscopy, Fourier Transform Infrared; Surface Properties | 2012 |
Synthesis and characterization of G5 PAMAM dendrimer containing daunorubicin for targeting cancer cells.
Topics: Daunorubicin; Dendrimers; Drug Carriers; Folic Acid; Humans; Molecular Structure; Neoplasms | 2012 |
[Effects of folic acid on cerebrovascular and cancer risks].
Topics: Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Neoplasms; Vitamin B Complex | 2012 |
Magnetic micelles as a potential platform for dual targeted drug delivery in cancer therapy.
Topics: Animals; Antibiotics, Antineoplastic; Cell Proliferation; Doxorubicin; Drug Delivery Systems; Ferric Compounds; Folate Receptors, GPI-Anchored; Folic Acid; Hep G2 Cells; Humans; Lactic Acid; Magnetic Fields; Magnetics; Male; Mice; Micelles; Nanoparticles; Neoplasms; NIH 3T3 Cells; Oxazines; Particle Size; Poloxamer; Polyesters; Polymers; Rabbits; Xanthenes | 2012 |
Luminescent/magnetic hybrid nanoparticles with folate-conjugated peptide composites for tumor-targeted drug delivery.
Topics: Antineoplastic Agents, Phytogenic; Cadmium Compounds; Camptothecin; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Folic Acid; Humans; Luminescence; Luminescent Agents; Magnetite Nanoparticles; Micelles; Neoplasms; Oligopeptides; Quantum Dots; Tellurium | 2012 |
Improved photodynamic cancer treatment by folate-conjugated polymeric micelles in a KB xenografted animal model.
Topics: Animals; Cell Line, Tumor; Female; Folic Acid; Humans; Mesoporphyrins; Mice; Micelles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Polymers | 2012 |
Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Cholesterol; Doxorubicin; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Liposomes; Mitochondria; Neoplasms; Oxidation-Reduction; Polyethylene Glycols; Reactive Oxygen Species | 2012 |
Dietary supplements and cancer prevention: balancing potential benefits against proven harms.
Topics: Antioxidants; Calcium Compounds; Chronic Disease; Dietary Supplements; Folic Acid; Humans; Neoplasms; Public Health; Randomized Controlled Trials as Topic; Risk Factors; Safety; Social Marketing; Trace Elements; United States; United States Food and Drug Administration; Vitamin B Complex; Vitamin D; Vitamins | 2012 |
Doxorubicin loaded silica nanorattles actively seek tumors with improved anti-tumor effects.
Topics: Animals; Antineoplastic Agents; Apoptosis; Doxorubicin; Drug Carriers; Female; Folic Acid; HeLa Cells; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasms; Polyethylene Glycols; Silicon Dioxide | 2012 |
Modular synthesis of folate conjugated ternary copolymers: polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate for targeted gene delivery.
Topics: Cell Line, Tumor; Click Chemistry; DNA; Endocytosis; Folic Acid; Humans; Neoplasms; Polyesters; Polyethyleneimine; Transfection | 2012 |
Contactless conductivity biosensor in microchip containing folic acid as bioreceptor.
Topics: Biomarkers, Tumor; Biosensing Techniques; Dimethylpolysiloxanes; Electric Conductivity; Electrodes; Folic Acid; Glass; Humans; Microfluidic Analytical Techniques; Neoplasms; Oxidation-Reduction | 2012 |
Photodynamic efficacy of photosensitizers under an attenuated light dose via lipid nano-carrier-mediated nuclear targeting.
Topics: Cell Death; Cell Nucleus; Cryoelectron Microscopy; Dose-Response Relationship, Radiation; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Light; Lipids; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Particle Size; Photochemotherapy; Photosensitizing Agents; Polysaccharides; Reproducibility of Results; Scattering, Radiation; Treatment Outcome | 2012 |
Folate-conjugated β-cyclodextrin from click chemistry strategy and for tumor-targeted drug delivery.
Topics: Antimetabolites, Antineoplastic; beta-Cyclodextrins; Cell Line, Tumor; Click Chemistry; Drug Carriers; Drug Delivery Systems; Endocytosis; Fluorouracil; Folic Acid; HeLa Cells; Humans; Nanoparticles; Neoplasms; Polyethylene Glycols | 2012 |
Multifunctional drug delivery system for targeting tumor and its acidic microenvironment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Drug Delivery Systems; Folic Acid; Hydrogen-Ion Concentration; Mice; Mice, Nude; Nanoparticles; Neoplasms; Paclitaxel; Polyamines; Polyethylene Glycols; Polymethacrylic Acids; Rats; Rats, Sprague-Dawley | 2012 |
Childhood cancer incidence trends in association with US folic acid fortification (1986-2008).
Topics: Child, Preschool; Female; Folic Acid; Food, Fortified; Humans; Incidence; Infant; Infant, Newborn; Male; Neoplasms; Nutrition Surveys; Registries; United States | 2012 |
High-sensitivity in vivo imaging for tumors using a spectral up-conversion nanoparticle NaYF4: Yb3+, Er3+ in cooperation with a microtubulin inhibitor.
Topics: Animals; Diagnostic Imaging; Erbium; Fluorescent Dyes; Fluorides; Folic Acid; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Nude; Microtubules; Nanoparticles; Neoplasms; Signal-To-Noise Ratio; Stilbenes; Tubulin Modulators; Ytterbium; Yttrium | 2012 |
Carrier-free, functionalized drug nanoparticles for targeted drug delivery.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Maleic Anhydrides; Nanoparticles; Neoplasms; Polyethylene Glycols | 2012 |
Folic acid fortification prevents neural tube defects and may also reduce cancer risks.
Topics: Canada; Dietary Supplements; Dose-Response Relationship, Drug; Europe; Female; Flour; Folic Acid; Food, Fortified; Global Health; Guidelines as Topic; Humans; Mandatory Programs; Neoplasms; Neural Tube Defects; Nutritional Requirements; Pregnancy; Pregnancy Complications; Prevalence; Program Evaluation; Risk Assessment; United States | 2012 |
Folate-conjugated thermo-responsive micelles for tumor targeting.
Topics: Acrylamide; Acrylates; Animals; Cell Line; Delayed-Action Preparations; Drug Delivery Systems; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Male; Mice; Mice, Nude; Micelles; Neoplasms; Temperature | 2012 |
Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic.
Topics: Biological Availability; Cell Line, Tumor; Dendrimers; Esterases; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Methotrexate; Molecular Targeted Therapy; Neoplasms; Tetrahydrofolate Dehydrogenase | 2012 |
Bacteria-mediated in vivo delivery of quantum dots into solid tumor.
Topics: Animals; Bifidobacterium; Carcinoma, Lewis Lung; Cell Membrane; Electroporation; Folic Acid; Male; Mice; Mice, Inbred C57BL; Neoplasms; Quantum Dots; Whole Body Imaging | 2012 |
Dietary folates and cancer risk in a network of case-control studies.
Topics: Case-Control Studies; Diet; Folic Acid; Humans; Neoplasms; Risk Factors; Taiwan | 2012 |
Appeal to the European food safety authority.
Topics: Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Neoplasms; Neural Tube Defects; Pregnancy; Pregnancy Complications | 2012 |
Folate-modified gold nanoclusters as near-infrared fluorescent probes for tumor imaging and therapy.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Cattle; Cell Line, Tumor; Doxorubicin; Fluorescent Dyes; Folate Receptor 1; Folic Acid; Gold; HCT116 Cells; Hep G2 Cells; Humans; Metal Nanoparticles; Mice; Mice, Nude; Neoplasms; Serum Albumin, Bovine; Spectroscopy, Near-Infrared; Tissue Distribution | 2012 |
Monitoring methotrexate in clinical samples from cancer patients during chemotherapy with a LSPR-based competitive sensor.
Topics: Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescence Polarization Immunoassay; Folic Acid; Gold; Humans; Metal Nanoparticles; Methotrexate; Neoplasms; Solid Phase Extraction; Surface Plasmon Resonance; Tandem Mass Spectrometry; Tetrahydrofolate Dehydrogenase | 2012 |
[Fewer tumors in children since folic acid supplementation: value of the B vitamin is possibly greater than expected].
Topics: Brain Neoplasms; Child; Dietary Supplements; Female; Folic Acid; Humans; Infant, Newborn; Kidney Neoplasms; Neoplasms; Pregnancy; Prenatal Care | 2012 |
Dietary folate does not significantly affect the intestinal microbiome, inflammation or tumorigenesis in azoxymethane-dextran sodium sulphate-treated mice.
Topics: Animals; Azoxymethane; Biomarkers; Colitis, Ulcerative; Colon; Colonic Neoplasms; Dextran Sulfate; Dextrans; Diet; Disease Progression; Folic Acid; Inflammation; Male; Mice; Mice, Inbred C57BL; Microbiota; Neoplasms; RNA, Ribosomal, 16S; Sulfates | 2013 |
Cancer targeting potential of folate targeted nanocarrier under comparative influence of tretinoin and dexamethasone.
Topics: Cell Survival; Dendrimers; Dexamethasone; Erythrocytes; Folate Receptors, GPI-Anchored; Folic Acid; Hemolysis; Humans; MCF-7 Cells; Nanoparticles; Neoplasms; Polypropylenes; Tretinoin | 2013 |
PEI-derivatized fullerene drug delivery using folate as a homing device targeting to tumor.
Topics: Administration, Intravenous; Animals; Apoptosis; Body Weight; Cell Line, Tumor; Cell Proliferation; Docetaxel; Drug Delivery Systems; Endocytosis; Female; Folic Acid; Fullerenes; Humans; Male; Mice; Mice, Inbred BALB C; Neoplasms; Particle Size; Polyethyleneimine; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Taxoids; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Overexpression of the mitochondrial folate and glycine-serine pathway: a new determinant of methotrexate selectivity in tumors.
Topics: Biological Transport; Folic Acid; Folic Acid Antagonists; Glycine; Humans; Methotrexate; Mitochondria; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Serine; Transcriptome | 2013 |
Folic acid as delivery vehicles: targeting folate conjugated fluorescent nanoparticles to tumors imaging.
Topics: Cell Line, Tumor; Drug Carriers; Fluorescent Dyes; Folic Acid; Humans; Nanoparticles; Neoplasms; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet | 2012 |
Synthesis and biological evaluation of a folate-targeted rhaponticin conjugate.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Stilbenes | 2013 |
Efficacy of adding folic acid to foods.
Topics: Cardiovascular Diseases; Diet; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Neoplasms; Neural Tube Defects; Vitamin B 12 Deficiency | 2012 |
Radiosynthesis and preclinical evaluation of 3'-Aza-2'-[(18)F]fluorofolic acid: a novel PET radiotracer for folate receptor targeting.
Topics: Animals; Aza Compounds; Cell Line, Tumor; Female; Fluorine Radioisotopes; Folate Receptors, GPI-Anchored; Folic Acid; Halogenation; Humans; Mice; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution | 2013 |
Protein-resistant, reductively dissociable polyplexes for in vivo systemic delivery and tumor-targeting of siRNA.
Topics: Animals; Cell Survival; Dextrans; Disease Models, Animal; Female; Folic Acid; Gene Silencing; Gene Transfer Techniques; HeLa Cells; Humans; KB Cells; Mice; Mice, Nude; Nanoparticles; Neoplasms; Polyethyleneimine; Protein Conformation; RNA, Small Interfering; Transfection | 2013 |
Global DNA hypomethylation in peripheral blood mononuclear cells as a biomarker of cancer risk.
Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Chromatography, Liquid; DNA; DNA Methylation; Female; Folic Acid; Genotype; Humans; Leukocytes, Mononuclear; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Polymorphism, Genetic; Prognosis; Retrospective Studies; Risk Factors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Folate-conjugated hybrid SBA-15 particles for targeted anticancer drug delivery.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Microscopy, Electron, Scanning; Nanoparticles; Neoplasms; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared | 2013 |
Natural killer cell cytotoxicity is not regulated by folic acid in vitro.
Topics: CD56 Antigen; Cytotoxicity, Immunologic; Dietary Supplements; Female; Folic Acid; Humans; Killer Cells, Natural; Leukocytes, Mononuclear; Male; Neoplasms; Receptors, IgG; Receptors, Natural Killer Cell; Tetrahydrofolates; Vitamin B Complex | 2013 |
Platinum folate nanoparticles toxicity: cancer vs. normal cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cells, Cultured; Folic Acid; Humans; Keratinocytes; Metal Nanoparticles; Microscopy, Electron, Transmission; Necrosis; Neoplasms; Platinum | 2013 |
Folic acid modified cationic γ-cyclodextrin-oligoethylenimine star polymer with bioreducible disulfide linker for efficient targeted gene delivery.
Topics: Aziridines; Carcinoma; Cell Line, Tumor; Disulfides; Folate Receptors, GPI-Anchored; Folic Acid; gamma-Cyclodextrins; Gene Transfer Techniques; Genetic Therapy; Humans; Neoplasms; Polymers | 2013 |
Folic acid and cancer--where are we today?
Topics: Carcinogens; Dietary Supplements; Female; Folic Acid; Humans; Male; Neoplasms | 2013 |
Folic acid-conjugated graphene oxide for cancer targeted chemo-photothermal therapy.
Topics: Antineoplastic Agents; Biological Transport; Doxorubicin; Drug Carriers; Folic Acid; Folic Acid Transporters; Graphite; HeLa Cells; Hot Temperature; Humans; Molecular Targeted Therapy; Nanostructures; Neoplasms; Oxides; Povidone | 2013 |
No evidence of cancer risk from folate supplements.
Topics: Dietary Supplements; Folic Acid; Global Health; Humans; Incidence; Neoplasms; Risk Factors | 2013 |
Preparation, characterization, and in vivo evaluation of doxorubicin loaded BSA nanoparticles with folic acid modified dextran surface.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Dextrans; Doxorubicin; Drug Carriers; Folic Acid; Male; Mice; Mice, Inbred ICR; Nanoparticles; Neoplasms; Serum Albumin, Bovine; Tumor Burden | 2013 |
A pH-sensitive doxorubicin prodrug based on folate-conjugated BSA for tumor-targeted drug delivery.
Topics: Animals; Antineoplastic Agents; Doxorubicin; Drug Delivery Systems; Folic Acid; Hydrogen-Ion Concentration; Mice; Microscopy, Electron, Transmission; Neoplasms; Prodrugs; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared | 2013 |
Modified dipeptide-based nanoparticles: vehicles for targeted tumor drug delivery.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Dipeptides; Doxorubicin; Drug Delivery Systems; Female; Folic Acid; Humans; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Phenylalanine | 2013 |
Enhanced tumor targeting and antitumor efficacy via hydroxycamptothecin-encapsulated folate-modified N-succinyl-N'-octyl chitosan micelles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Mice; Mice, Nude; Micelles; Neoplasms; Rats | 2013 |
Fruit and vegetable intake and chronic disease risk in Portugal.
Topics: Antioxidants; Biomarkers; Cardiovascular Diseases; Carotenoids; Female; Folic Acid; Fruit; Homocysteine; Humans; Male; Middle Aged; Morbidity; Neoplasms; Portugal; Risk Factors; Surveys and Questionnaires; Vegetables; Vitamin B 12; Vitamin B 6; Vitamin E | 2002 |
Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice.
Topics: Animals; Cadherins; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Exons; Folic Acid; Folic Acid Deficiency; Mice; Mice, Inbred C57BL; Mutation; Neoplasms; Promoter Regions, Genetic; S-Adenosylmethionine; Tumor Suppressor Protein p53 | 2003 |
A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Chromosomes, Human, Pair 1; Cohort Studies; Diet; Folic Acid; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Longitudinal Studies; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Prospective Studies; Smoking | 2003 |
Synthesis of adenoviral targeting molecules by intein-mediated protein ligation.
Topics: Adenoviridae; Apolipoproteins E; Fibroblast Growth Factor 2; Folic Acid; Genetic Engineering; Genetic Therapy; Genetic Vectors; Humans; Ligands; Neoplasms; Protein Binding; Receptors, Cell Surface; Tumor Cells, Cultured | 2003 |
Polymeric micelle for tumor pH and folate-mediated targeting.
Topics: Antibiotics, Antineoplastic; Carrier Proteins; Chemical Phenomena; Chemistry, Physical; Doxorubicin; Drug Delivery Systems; Endocytosis; Female; Folate Receptors, GPI-Anchored; Folic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Light; Micelles; Microscopy, Confocal; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Receptors, Cell Surface; Scattering, Radiation; Tumor Cells, Cultured | 2003 |
[Folic acid antagonists in therapy of leukemia and tumors; problem of resistance and relations with the citrovorum factor].
Topics: Folic Acid; Folic Acid Antagonists; Humans; Leucovorin; Leukemia; Neoplasms | 1952 |
Role of folic acid and citrovorum factor in metabolic processes and their relation to cancer.
Topics: Antimetabolites; Biochemical Phenomena; Folic Acid; Leucovorin; Leukemia; Neoplasms | 1952 |
Combination chemotherapy of cancer: potentiation of carcinostatic activity of 8-azaguanine by 6-formylpteridine.
Topics: Animals; Antimetabolites; Azaguanine; Drug Therapy, Combination; Folic Acid; Guanine; Neoplasms; Neoplasms, Experimental | 1952 |
[Utility of oxidoreductive vitamins (PP, C and B complex) in cancer therapy].
Topics: Ascorbic Acid; Folic Acid; Humans; Neoplasms; Niacin; Nicotinic Acids; Vitamin A; Vitamin B Complex; Vitamin K; Vitamins | 1953 |
Folic-acid-excretion studies in the investigation of malignant disease.
Topics: Biological Transport; Body Fluids; Folic Acid; Humans; Neoplasms; Research | 1953 |
[The peroral folic acid test and its value for clinical differential diagnosis. I..].
Topics: Anemia; Body Fluids; Diagnosis, Differential; Folic Acid; Hematologic Tests; Humans; Neoplasms | 1954 |
[Effect of vitamin B complex on transplantable Guerin's epithelioma].
Topics: Carcinoma; Folic Acid; Neoplasm Transplantation; Neoplasms; Vitamin B Complex | 1954 |
[Clinical aspects of secondary pellagra].
Topics: Digestive System Neoplasms; Folic Acid; Gastrointestinal Tract; Humans; Liver Cirrhosis; Neoplasms; Pellagra; Vitamin B Complex | 1954 |
The effect of vitamin variations upon the tumor incidence of a tu-e strain of Drosophila melanogaster.
Topics: Animals; Diptera; Drosophila melanogaster; Folic Acid; Incidence; Neoplasms; Neoplasms, Experimental; Vitamin B Complex; Vitamins | 1955 |
The effects of vitamin analogs upon tumor penetrance in a tu-e strain of Drosophila melanogaster.
Topics: Animals; Diptera; Drosophila melanogaster; Folic Acid; Neoplasms; Neoplasms, Experimental; Penetrance; Vitamin B Complex; Vitamins | 1955 |
[Observations on peroral folic acid shock test in malignant tumors of the upper respiratory tract and of the ear].
Topics: Eustachian Tube; Folic Acid; Humans; Larynx; Neoplasms; Nose; Respiratory Tract Neoplasms | 1956 |
Combination chemotherapy: synergism between a possible folic acid antagonist and ethionine on a solid tumor.
Topics: Antineoplastic Agents; Drug Therapy, Combination; Ethionine; Folic Acid; Folic Acid Antagonists; Humans; Neoplasms | 1957 |
[The value of a peroral folic acid excretion test for the diagnosis of carcinoma].
Topics: Biological Transport; Body Fluids; Carcinoma; Folic Acid; Hematologic Tests; Humans; Neoplasms | 1957 |
[Recurrence of acute phase in leukemia; functional recuperation of normal granulopoiesis with therapeutic use of citrovorum factor].
Topics: Folic Acid; Leucovorin; Leukemia; Neoplasms; Recurrence | 1955 |
FOLACIN and riboflavin.
Topics: Enterococcus faecalis; Folic Acid; Humans; Maxillary Sinus; Maxillary Sinus Neoplasms; Neoplasms; Riboflavin | 1959 |
[Study on the metabolism of folic acid in Hodgkin's disease and in malignant neoplasms].
Topics: Folic Acid; Hodgkin Disease; Humans; Neoplasms | 1959 |
[First results in the study of new structural analogues of folic acid].
Topics: Folic Acid; Folic Acid Antagonists; Humans; Inorganic Chemicals; Neoplasms; Organic Chemicals | 1959 |
[Silver cancer and tissue respiration. Reactivity of the element on imidazole. Extensive research with folic acid].
Topics: Folic Acid; Imidazoles; Metabolism; Neoplasms; Research; Silver; Silver Compounds | 1962 |
Studies on the folic acid vitamins. VII. The effects of large doses of amethopterin in patients with cancer.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Folic Acid; Folic Acid Antagonists; Methotrexate; Neomycin; Neoplasms; Vitamins | 1962 |
Cancer therapy by intra-arterial methotrexate infusion. Protection of mucous membranes by topically applied citrovorum factor with hyaluronidase.
Topics: Folic Acid; Folic Acid Antagonists; Hyaluronoglucosaminidase; Infusions, Intra-Arterial; Leucovorin; Methotrexate; Mouth; Mucous Membrane; Neoplasms; Pharynx | 1962 |
[On the value of the urinary folic acid excretion test for diagnosis of malignant disease].
Topics: Body Fluids; Folic Acid; Humans; Lung Neoplasms; Neoplasms | 1963 |
[Study of an enzymatic autolysate, "M-23-1-C (Magnantyl)", in patients with neoplasms].
Topics: Amino Acids; Folic Acid; Humans; Neoplasms; Trace Elements; Vitamin B Complex | 1963 |
Low serum-folic-acid in malignancy.
Topics: Folic Acid; Humans; Neoplasms | 1963 |
[WHY 200 YEARS OF SCIENTIFIC RESEARCH ON CANCER HAVE BEEN A DISILLUSIONMENT].
Topics: Allergy and Immunology; Copper; Epidemiology; Fertilizers; Folic Acid; History; Magnesium; Metabolism; Neoplasms; Nutritional Physiological Phenomena; Nutritional Sciences; Nutritional Status; Phospholipids; Potassium; Research; Triticum; Vitamin B Complex | 1963 |
[THE TEST OF THE URINARY ELIMINATION OF FOLIC ACID. ITS VALUE IN THE DIAGNOSIS OF CANCER].
Topics: Body Fluids; Folic Acid; Humans; Neoplasms; Urine | 1963 |
DETERMINATIONS OF THE LEVELS OF SERUM FOLATE IN PATIENTS WITH CARCINOMA OF THE HEAD AND NECK TREATED WITH METHOTREXATE.
Topics: Blood Chemical Analysis; Carcinoma, Squamous Cell; Folic Acid; Humans; Methotrexate; Nasopharyngeal Neoplasms; Neoplasms; Nose Neoplasms; Osteosarcoma; Pathology; Pharmacology; Pharyngeal Neoplasms; Sarcoma; Tongue Neoplasms | 1964 |
A DIRECT ASSAY FOR DIHYDROFOLATE REDUCTASE IN HUMAN LEUKOCYTES.
Topics: Animals; Chemistry Techniques, Analytical; Folic Acid; Folic Acid Antagonists; Humans; Leukemia; Leukemia L1210; Leukemia, Myeloid; Leukocytes; Methotrexate; Mice; Microchemistry; NADP; Neoplasms; Oxidoreductases; Research; Spectrophotometry; Tetrahydrofolate Dehydrogenase | 1964 |
SOME INVESTIGATIONS OF FOLIC-ACID DEFICIENCY.
Topics: Anemia; Anemia, Hemolytic; Anemia, Macrocytic; Anticonvulsants; Biomedical Research; Blood Chemical Analysis; Female; Folic Acid; Folic Acid Deficiency; Geriatrics; Glutamates; Histidine; Leukemia; Liver Diseases; Metabolism; Neoplasms; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Urine; Vitamin B 12 Deficiency | 1964 |
THE CHEMOTHERAPY OF CANCER WITH MASSIVE DOSES UNDER THE PROTECTION OF PERFUSION OF AUTOGENOUS HEMATOPOIETIC TISSUE.
Topics: Adenine; Bone Marrow Transplantation; Breast Neoplasms; DNA; Female; Folic Acid; Humans; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Melphalan; Neoplasms; Ovarian Neoplasms; Perfusion; Sarcoma; Thiotepa; Triethylenemelamine | 1964 |
[LABORATORY TESTS FOR VERIFYING STATES OF FOLIC ACID DEFICIENCY IN THE ORGANISM].
Topics: Aminopterin; Anemia; Anemia, Macrocytic; Anticonvulsants; Biological Assay; Blood; Clinical Laboratory Techniques; Folic Acid; Folic Acid Deficiency; Histidine; Humans; Lactobacillus; Leuconostoc; Liver Diseases; Methotrexate; Neoplasms; Nutrition Disorders; Pregnancy; Staphylococcus; Urine; Vitamin B Deficiency | 1964 |
QUANTITATIVE COLONIAL GROWTH OF MAMMALIAN CELLS IN FIBRIN CELLS.
Topics: Asparagine; Fibrin; Folic Acid; Immune Sera; Mast Cells; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Serine; Thrombin; Tissue Culture Techniques | 1964 |
URINARY FORMIMINOGLUTAMIC ACID EXCRETION IN PATIENTS WITH NEOPLASTIC DISEASE.
Topics: Anemia; Anemia, Macrocytic; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formiminoglutamic Acid; Histidine; Humans; Metabolism; Neoplasms; Urine; Vitamin B Deficiency | 1964 |
AN EVALUATION OF THE MEASUREMENT OF URINARY FORMIMINOGLUTAMIC ACID EXCRETION AS AN INDICATION OF DISTURBED FOLIC ACID METABOLISM.
Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Celiac Disease; Female; FIGLU Test; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Formiminoglutamic Acid; Histidine; Humans; Intestinal Diseases; Intestine, Small; Intestines; Liver Diseases; Metabolic Diseases; Neoplasms; Postoperative Complications; Pregnancy; Sprue, Tropical; Vitamin B 12 | 1964 |
RETICULUM CELL SARCOMA OF THE SMALL BOWEL AND STEATORRHOEA.
Topics: Ascorbic Acid; Blood Transfusion; Body Weight; Bone Marrow Examination; Celiac Disease; Diet; Diet Therapy; Fats; Feces; Folic Acid; Humans; Intestinal Neoplasms; Intestinal Perforation; Intestine, Small; Iron; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Nandrolone; Neomycin; Neoplasms; Pathology; Prednisone; Sarcoma; Steatorrhea; Surgical Procedures, Operative; Vitamin A; Vitamin B 12; Vitamin B Complex; Vitamins; Water-Electrolyte Balance | 1964 |
[TRIAL TREATMENT OF VARIOUS "PROTEUS" INFECTIONS WITH 2,4-DIAMINO-5-(3,4,5-TRIMETHOXYBENZYL) PYRIMIDINE, OR (TRIM'ETHOPRIME)].
Topics: Drug Synergism; Drug Therapy; Folic Acid; Hematologic Diseases; Humans; Metabolism; Neoplasms; Polymethacrylic Acids; Proteus; Proteus Infections; Pyrimidines; Respiratory Tract Infections; Sepsis; Skin Diseases; Sulfonamides; Urinary Tract Infections | 1965 |
FOLIC ACID ACTIVITY IN LEUKEMIA AND CANCER.
Topics: Animals; Avian Leukosis Virus; Biological Assay; Blood; Blood Cell Count; Blood Sedimentation; Folic Acid; Geriatrics; Hemoglobins; Hodgkin Disease; Humans; Lactobacillus; Leukemia; Neoplasm Metastasis; Neoplasms; Plasma; Poultry | 1965 |
[ANTI-CANCER CHEMOTHERAPY BY PROLONGED INTRA-ARTERIAL INFUSIONS].
Topics: Adrenal Cortex Hormones; Aminocaproates; Aminocaproic Acid; Anti-Bacterial Agents; Chemotherapy, Cancer, Regional Perfusion; Coagulase; Drug Therapy; Fluorouracil; Folic Acid; Humans; Hydrolases; Infusions, Intra-Arterial; Methotrexate; Neoplasms; Thiotepa; Vitamin B Complex | 1965 |
CLOSED PELVIC PERFUSION IN ADVANCED GYNECOLOGIC CANCER.
Topics: Catheterization; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Folic Acid; Genital Neoplasms, Female; Geriatrics; Humans; Lymphography; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Pelvis; Postoperative Care; Prognosis; Toxicology; Uracil; Uracil Mustard; Urography; Uterine Cervical Neoplasms; Vulvar Neoplasms | 1965 |
[THE FOLIC ACID TEST. ATTEMPT AT EARLY DETECTION OF CANCER].
Topics: Body Fluids; Early Detection of Cancer; Early Diagnosis; Folic Acid; Hematologic Tests; Humans; Neoplasms; Urine | 1965 |
The effect of combined irradiation and chemotherapy on cancer growth with special reference to studies with folic acid analogues.
Topics: Animals; Folic Acid; Folic Acid Antagonists; Neoplasms; Neoplasms, Experimental; Radiotherapy | 1959 |
Inhibition of the growth of an ame-thopterin-refractory tumor by dietary restriction of folic acid.
Topics: Carcinosarcoma; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Humans; Neoplasms | 1962 |
Preparation of 66Ga- and 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals.
Topics: Animals; Autoradiography; Carrier Proteins; Deferoxamine; Feasibility Studies; Fluorodeoxyglucose F18; Folate Receptors, GPI-Anchored; Folic Acid; Gallium Radioisotopes; Humans; Isotope Labeling; KB Cells; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Radiopharmaceuticals; Receptors, Cell Surface; Tomography, Emission-Computed | 2003 |
Joint association of alcohol and folate intake with risk of major chronic disease in women.
Topics: Adult; Cardiovascular Diseases; Chronic Disease; Confidence Intervals; Drug Interactions; Ethanol; Female; Folic Acid; Follow-Up Studies; Humans; Life Style; Middle Aged; Neoplasms; Prospective Studies; Risk Factors; Smoking; Surveys and Questionnaires; United States | 2003 |
Optical imaging of metastatic tumors using a folate-targeted fluorescent probe.
Topics: Animals; Biomarkers, Tumor; Carrier Proteins; Cell Line, Tumor; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasms; Neoplasms, Unknown Primary; Peritoneal Neoplasms; Receptors, Cell Surface; Skin Neoplasms | 2003 |
A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the reduced folate carrier.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Blotting, Northern; Blotting, Southern; Cell Division; Cell Line, Tumor; DNA, Complementary; Dose-Response Relationship, Drug; Folic Acid; Gene Deletion; HeLa Cells; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Leucovorin; Membrane Transport Proteins; Methotrexate; Neoplasms; Reduced Folate Carrier Protein; Time Factors; Transfection | 2004 |
Studies on the mechanism of action of chemotherapeutic agents in cancer. I. A sex difference in toxicity to the folic acid analogue, 4-amino-pteroylglutamic acid.
Topics: Antineoplastic Agents; Folic Acid; Folic Acid Antagonists; Neoplasms; Sex Characteristics | 1950 |
Studies on the mechanism of action of chemotherapeutic agents in cancer. II. Requirements for the prevention of aminopterin toxicity by folic acid in mice.
Topics: Aminopterin; Animals; Antineoplastic Agents; Biomedical Research; Folic Acid; Folic Acid Antagonists; Mice; Neoplasms | 1950 |
Studies on the mechanism of action of chemotherapeutic agents in cancer. III. Relationship of genital growth response in mice to the folic acid analogue, 4-amino-pteroylglutamic acid.
Topics: Animals; Antineoplastic Agents; Folic Acid; Folic Acid Antagonists; Mice; Neoplasms; Urogenital System | 1950 |
The influence of riboflavin, pyridoxine, inositol, and protein depletion- repletion upon the induction of neoplasms by choline deficiency.
Topics: Choline Deficiency; Folic Acid; Humans; Inositol; Neoplasms; Pyridoxine; Riboflavin; Vitamin B Complex | 1950 |
[Lymphosarcoma in an infant treated with N-4 (2 amino-4 hydroxy-pteridyl-6 methylamino) benzoylglutamic acid].
Topics: Folic Acid; Humans; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma | 1950 |
Studies on the mechanism of action of chemotherapeutic agents in cancer. V. Influence of the citrovorum factor and folic acid on the toxic manifestations of aminopterin in mice.
Topics: Aminopterin; Animals; Antineoplastic Agents; Cobalt; Folic Acid; Folic Acid Antagonists; Leadership; Leucovorin; Mice; Neoplasms | 1951 |
Folic acid analogs and the growth of embryo and tumor tissue.
Topics: Folic Acid; Folic Acid Antagonists; Humans; Neoplasms | 1951 |
The "second-look" in cancer surgery; a patient with colic cancer and involved lymph nodes negative on the "sixth-look".
Topics: Colic; Folic Acid; Humans; Lymph Nodes; Neoplasms; Second-Look Surgery | 1951 |
[Investigation of folic acid antagonist therapy in cancer of hemopoietic organs and leukemia].
Topics: Folic Acid; Folic Acid Antagonists; Hematopoietic System; Leukemia; Neoplasms | 1951 |
The role of alpha-folate receptor-mediated transport in the antitumor activity of antifolate drugs.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Inhibitory Concentration 50; Models, Chemical; Neoplasms; Pemetrexed; Quinazolines; Receptors, Cell Surface; Thiophenes; Time Factors | 2004 |
Comparison of cell uptake, biodistribution and tumor retention of folate-coated and PEG-coated gadolinium nanoparticles in tumor-bearing mice.
Topics: Animals; Coated Materials, Biocompatible; Disease Models, Animal; Endocytosis; Female; Folic Acid; Gadolinium; Humans; KB Cells; Mice; Mice, Nude; Nanotechnology; Neoplasms; Particle Size; Polyethylene Glycols; Technology, Pharmaceutical; Tissue Distribution | 2004 |
A full plate for future investigation in the diet-cancer connection.
Topics: Alcohol Drinking; Animals; Calcium Compounds; Dietary Fiber; Feeding Behavior; Folic Acid; Humans; Neoplasms; Risk Factors; Selenium Compounds; Vitamins | 2004 |
Pteroyl-gamma-glutamate-cysteine synthesis and its application in folate receptor-mediated cancer cell targeting using folate-tethered liposomes.
Topics: Caco-2 Cells; Carrier Proteins; Chromatography, High Pressure Liquid; Cysteine; Doxorubicin; Fluoresceins; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Liposomes; Neoplasms; Phosphatidylethanolamines; Polyethylene Glycols; Receptors, Cell Surface | 2004 |
Preparation and characterization of methoxy poly(ethylene glycol)/poly(epsilon-caprolactone) amphiphilic block copolymeric nanospheres for tumor-specific folate-mediated targeting of anticancer drugs.
Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Cells, Cultured; Coated Materials, Biocompatible; Drug Delivery Systems; Ethylene Glycols; Fibroblasts; Folic Acid; Humans; Materials Testing; Molecular Weight; Nanotubes; Neoplasms; Paclitaxel; Particle Size; Polyesters | 2005 |
A report on the use of sodium pteroyl triglutamate in 413 cases.
Topics: Folic Acid; Humans; Ions; Neoplasms; Sodium; Sodium, Dietary | 1949 |
The influence of vitamins of the B complex on the induction of epithelial tumors in mice.
Topics: Animals; Folic Acid; Mice; Neoplasms; Vitamin B Complex; Vitamins | 1949 |
Inhibiting action of some analogues of folic acid on the growth of plant tumours.
Topics: Folic Acid; Neoplasms; Physiological Phenomena; Plant Tumors | 1949 |
Report of the use of pteroyltriglutamic and pteroyldiglutamic acid at the Grace Hospital Tumor Clinic.
Topics: Folic Acid; Humans; Neoplasms | 1950 |
Chemotherapeutic studies of tumors, including leukemia, in children.
Topics: Folic Acid; Humans; Leukemia; Neoplasms | 1950 |
Toxic reactions of 4-amino-pteroylglutamic acid (aminopterin) in patients with far-advanced neoplastic disease.
Topics: Aminopterin; Folic Acid; Humans; Neoplasms; Postoperative Complications | 1950 |
Therapeutic uses of the vitamins B; malignancy.
Topics: Folic Acid; Humans; Neoplasms; Vitamin B Complex; Vitamins | 1950 |
Folic acid analogs and experimental tumors.
Topics: Folic Acid; Humans; Neoplasms | 1950 |
Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Folic Acid; Methacrylates; Mice; Neoplasm Transplantation; Neoplasms; Polymers; Rhodamines; Vitamin B 12 | 2004 |
Lack of impact of the loss of constitutive folate receptor alpha expression, achieved by RNA Interference, on the activity of the new generation antifolate pemetrexed in HeLa cells.
Topics: Apoptosis; Base Sequence; Blotting, Northern; Carrier Proteins; Fluorescent Antibody Technique; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Formyltetrahydrofolates; Glutamates; Guanine; HeLa Cells; Humans; Molecular Sequence Data; Neoplasms; Pemetrexed; Receptors, Cell Surface; RNA Interference; Thymidylate Synthase; Tumor Cells, Cultured | 2004 |
Dietary folate intake and k-ras mutations in sporadic colon and rectal cancer in The Netherlands Cohort Study.
Topics: Aged; Cohort Studies; Colonic Neoplasms; Diet; DNA Mutational Analysis; Female; Folic Acid; Genes, ras; Humans; Male; Middle Aged; Mutation; Neoplasms; Netherlands; Rectal Neoplasms; Risk; Sex Factors | 2005 |
Targeting cancer cells with DNA-assembled dendrimers: a mix and match strategy for cancer.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Dendrimers; DNA, Complementary; Drug Carriers; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Nanotechnology; Neoplasms; Oligonucleotides; Protein Binding; Receptors, Cell Surface | 2005 |
Folate conjugated fluorescent silica nanoparticles for labeling neoplastic cells.
Topics: Biomarkers, Tumor; Carrier Proteins; Cell Line; Coated Materials, Biocompatible; Fibroblasts; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Materials Testing; Microscopy, Fluorescence; Nanotubes; Neoplasms; Particle Size; Receptors, Cell Surface; Silicon Dioxide; Staining and Labeling | 2005 |
Folate-conjugated methoxy poly(ethylene glycol)/poly(epsilon-caprolactone) amphiphilic block copolymeric micelles for tumor-targeted drug delivery.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Delivery Systems; Female; Fluorescent Dyes; Folic Acid; Humans; Kinetics; Micelles; Microscopy, Confocal; Neoplasms; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols | 2005 |
Folate levels and cancer morbidity and mortality: prospective cohort study from Busselton, Western Australia.
Topics: Adult; Aged; Aged, 80 and over; Australia; Breast Neoplasms; Cohort Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Morbidity; Mortality; Neoplasms; Prospective Studies; Prostatic Neoplasms | 2006 |
Patient information. Folic acid: for pregnancy and more.
Topics: Alzheimer Disease; Depression; Dietary Supplements; Female; Folic Acid; Heart Diseases; Humans; Male; Neoplasms; Neural Tube Defects; Nutrition Policy; Nutritional Requirements; Pregnancy | 2006 |
Preparation and in vitro and in vivo evaluation of technetium-99m-labeled folate and methotrexate conjugates as tumor imaging agents.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Folic Acid; Humans; Isotope Labeling; Methotrexate; Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Technetium; Tissue Distribution | 2006 |
Folate supplementation: too much of a good thing?
Topics: Carcinogens; Cardiovascular Diseases; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Neoplasms; Neural Tube Defects; Preconception Care; Vitamin B Complex | 2006 |
On systems and control approaches to therapeutic gain.
Topics: Antineoplastic Agents; Core Binding Factor Alpha 2 Subunit; DNA Repair; DNA, Neoplasm; Drug Resistance, Neoplasm; Folic Acid; Fusion Proteins, bcr-abl; Humans; Idoxuridine; Models, Biological; Neoplasms; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiation-Sensitizing Agents; Systems Biology; Systems Theory | 2006 |
In vitro and in vivo targeting of different folate receptor-positive cancer cell lines with a novel 99mTc-radiofolate tracer.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Metabolic Clearance Rate; Mice; Molecular Probe Techniques; Neoplasms; Organ Specificity; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Cell Surface; Technetium; Tissue Distribution | 2006 |
Synthesis and preclinical evaluation of a folic acid derivative labeled with 18F for PET imaging of folate receptor-positive tumors.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Chromatography, High Pressure Liquid; Fluorodeoxyglucose F18; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Mice; Mice, Nude; Models, Chemical; Neoplasms; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Receptors, Cell Surface | 2006 |
[Uncertain effects of folic acid on disorders other than neural-tube defects].
Topics: Animals; Cardiovascular Diseases; Cognition Disorders; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Neoplasms; Prenatal Care; Vitamin B 12 Deficiency | 2006 |
Synthesis and characterization of chitosan-g-poly(ethylene glycol)-folate as a non-viral carrier for tumor-targeted gene delivery.
Topics: Carrier Proteins; Chitosan; DNA; Drug Carriers; Folate Receptors, GPI-Anchored; Folic Acid; Gene Transfer Techniques; Genetic Vectors; Humans; Hydrogen-Ion Concentration; Models, Chemical; Neoplasms; Plasmids; Polyethylene Glycols; Receptors, Cell Surface; Solubility; Water | 2007 |
[Uncertain effects of folic acid on disorders other than neural-tube defects].
Topics: Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms | 2006 |
Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12.
Topics: Cognition Disorders; Dose-Response Relationship, Drug; Folic Acid; Food, Fortified; Homocysteine; Humans; Immune System; Neoplasms; Nutrition Policy; Vitamin B 12; Vitamin B Complex | 2007 |
Folate levels in cancer: a vitamin for a new challenge.
Topics: Biosynthetic Pathways; Cell Cycle Proteins; Folic Acid; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Polo-Like Kinase 1; Polymorphism, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins | 2007 |
Hyperhomocysteinaemia and immune activation in patients with cancer.
Topics: Aged; Biomarkers; Case-Control Studies; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immune System; Male; Neoplasms; Neopterin; Vitamin B 12 | 2007 |
Association of vitamin B12, folate and homocysteine with functional and pathological characteristics of the elderly in a mountainous village in Sicily.
Topics: Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Diabetes Mellitus; Folic Acid; Homocysteine; Humans; Middle Aged; Neoplasms; Peripheral Vascular Diseases; Sicily; Stroke; Vitamin B 12 | 2007 |
Folate-related genes and the risk of tobacco-related cancers in Central Europe.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Case-Control Studies; Europe; Folic Acid; Genetic Predisposition to Disease; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Nicotiana; Polymorphism, Single Nucleotide; Risk Factors | 2007 |
Folate and cancer--timing is everything.
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Folic Acid; Humans; Neoplasms; Risk; Treatment Failure | 2007 |
Should folic acid fortification be mandatory? No.
Topics: Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Legislation, Food; Neoplasms; Pregnancy; Pregnancy Complications | 2007 |
Should folic acid fortification be mandatory? Yes.
Topics: Dietary Supplements; Female; Folic Acid; Food, Fortified; Humans; Legislation, Food; Neoplasms; Preconception Care; Pregnancy; Pregnancy Complications | 2007 |
Folic acid fortification: Clarify the neurological risks.
Topics: Dietary Supplements; Folic Acid; Humans; Neoplasms; Nervous System Diseases; Risk Factors; Vitamin B 12 Deficiency | 2007 |
Folate and cancer prevention: a closer look at a complex picture.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Dietary Supplements; Folic Acid; Humans; Neoplasms | 2007 |
Isostructural folate conjugates radiolabeled with the matched pair 99mTc/188Re: a potential strategy for diagnosis and therapy of folate receptor-positive tumors.
Topics: Animals; Antineoplastic Agents; Buffers; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Isotope Labeling; KB Cells; Kidney; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Pemetrexed; Phosphates; Radioisotopes; Radiopharmaceuticals; Receptors, Cell Surface; Rhenium; Technetium; Tissue Distribution | 2007 |
Dose-dependent effects of (anti)folate preinjection on 99mTc-radiofolate uptake in tumors and kidneys.
Topics: Animals; Dose-Response Relationship, Drug; Female; Folic Acid; Folic Acid Antagonists; Humans; KB Cells; Kidney; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organotechnetium Compounds; Radiopharmaceuticals; Tetrahydrofolates; Tissue Distribution | 2007 |
Research update: the benefits of folate.
Topics: Cognition Disorders; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Humans; Middle Aged; Myocardial Infarction; Neoplasms; Stroke; Vitamin B Complex | 2007 |
Magnetic lymphatic targeting drug delivery system using carbon nanotubes.
Topics: Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Lymph Nodes; Lymphatic System; Magnetics; Medical Oncology; Models, Theoretical; Nanotechnology; Nanotubes, Carbon; Neoplasms | 2008 |
Folate-mediated tumor cell uptake of quantum dots entrapped in lipid nanoparticles.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lipids; Mice; Microscopy, Electron, Transmission; Nanoparticles; Neoplasm Transplantation; Neoplasms; Particle Size; Quantum Dots; Receptors, Cell Surface; Spectrophotometry, Ultraviolet | 2007 |
Resistance to tumour growth in rats fed on vitamin-B complex.
Topics: Animals; Folic Acid; Neoplasms; Rats; Vitamin B Complex; Vitamins | 1949 |
Some observations on the effect of folic acid antagonists on acute leukemia and other forms of incurable cancer.
Topics: Acute Disease; Folic Acid; Folic Acid Antagonists; Humans; Leukemia; Neoplasms; Vitamin B Complex; Vitamins | 1949 |
Inhibition of development of sarcoma 180 by 4-amino-N10-methyl pteroylglutamic acid.
Topics: Amino Acids; Animals; Folic Acid; Myosarcoma; Neoplasms; Sarcoma; Sarcoma 180 | 1949 |
Folic acid and antagonists in neoplastic disease.
Topics: Folic Acid; Humans; Neoplasms; Vitamin B Complex; Vitamins | 1949 |
Effect of antifolic acid derivatives on patients with far-advanced carcinomatosis.
Topics: Carcinoma; Folic Acid; Folic Acid Antagonists; Neoplasms | 1948 |
Effect of pteroylglutamic acid and vitamin B12 on growth of Rous tumor implants.
Topics: Corrinoids; Folic Acid; Hematinics; Humans; Neoplasms; Vitamin B 12; Vitamin B Complex | 1949 |
Bone marrow of mice bearing sarcoma 180 treated with 4-amino-pteroylglutamic acid and with 4-amino-N10-methyl-pteroylglutaminic acid.
Topics: Aminopterin; Animals; Bone and Bones; Bone Marrow; Bone Neoplasms; Folic Acid; Mice; Neoplasms; Sarcoma 180; Sarcoma, Experimental | 1949 |
Is folic acid good for everyone?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cognition; Epigenesis, Genetic; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Neural Tube Defects; Nutrition Policy; Nutritional Requirements; Public Health; Vitamin B 12 Deficiency | 2008 |
Antitumoral activity of PEG-gemcitabine prodrugs targeted by folic acid.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Cytidine Deaminase; Deoxycytidine; Drug Carriers; Drug Stability; Female; Folic Acid; Gemcitabine; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Polyethylene Glycols; Prodrugs | 2008 |
Reduction of the genomic damage level in haemodialysis patients by folic acid and vitamin B12 supplementation.
Topics: Aged; Aged, 80 and over; Case-Control Studies; DNA Damage; Female; Folic Acid; Genome, Human; Homocysteine; Humans; Kidney Failure, Chronic; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Neoplasms; Prospective Studies; Renal Dialysis; Vitamin B 12 | 2008 |
Exploratory study of 99mTc-EC20 imaging for identifying patients with folate receptor-positive solid tumors.
Topics: Adult; Aged; Aged, 80 and over; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Male; Middle Aged; Neoplasms; Oligopeptides; Pilot Projects; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Cell Surface; Reproducibility of Results; Sensitivity and Specificity; Technetium | 2008 |
An apple a day may be safer than vitamins.
Topics: Adenoma; Animals; Antioxidants; Colonic Neoplasms; Colonic Polyps; Dietary Supplements; Drug Synergism; Feeding Behavior; Folic Acid; Fruit; Humans; Malus; Neoplasms; Safety; Vegetables; Vitamins | 2008 |
Folate activity in serum and red cells of patients with cancer.
Topics: Adolescent; Adult; Aged; Bile Duct Neoplasms; Erythrocytes; Female; Folic Acid; Gallbladder Neoplasms; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Nutrition Disorders | 1967 |
Constitutive fragile sites and cancer.
Topics: Adolescent; Adult; Animals; Caffeine; Cells, Cultured; Child; Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; Female; Floxuridine; Folic Acid; Gorilla gorilla; Humans; Male; Middle Aged; Neoplasms; Pan troglodytes; Thymidine | 1984 |
[Vitamin B12 as a regulator and methotrexate as an antagonist of folic acid metabolism. Pathophysiologic and clinical aspects].
Topics: DNA; Folic Acid; Folic Acid Deficiency; Humans; Leucovorin; Methotrexate; Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 1983 |
Similar specificity of membrane transport for folate analogues and their metabolites by murine and human tumor cells: a clinically directed laboratory study.
Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line; Cell Membrane; Female; Folic Acid; Humans; Kinetics; Leukemia; Leukemia L1210; Neoplasms; Sarcoma 180; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 1984 |
Enzyme therapy: problems and solutions.
Topics: Animals; Arginine; Blood Coagulation Disorders; Enzyme Therapy; Enzymes; Enzymes, Immobilized; Erwinia; Escherichia coli; Fabry Disease; Folic Acid; gamma-Glutamyl Hydrolase; Gaucher Disease; Humans; Hydrogen-Ion Concentration; Kinetics; Lysosomes; Metabolic Clearance Rate; Neoplasms; Poisoning; Ribonucleases; Urokinase-Type Plasminogen Activator | 1982 |
Human red blood cell membrane oxidase and horseradish peroxidase cleavage of folic acid: evidence for formation of singlet oxygen.
Topics: Animals; Chemical Phenomena; Chemistry; Erythrocyte Membrane; Erythrocytes; Female; Folic Acid; Horseradish Peroxidase; Humans; Neoplasms; Oxygen Consumption; Peroxidases; Rats; Xanthine Oxidase | 1982 |
Chemoprevention of Cancer with Retinoids.
Topics: Animals; Etretinate; Female; Folic Acid; Humans; Isomerism; Isotretinoin; Neoplasms; Neoplasms, Experimental; Skin Neoplasms; Tretinoin; Uterine Cervical Neoplasms; Vitamin A; Vitamin E | 1981 |
Folate metabolism in man: the effect of malignant disease.
Topics: 4-Aminobenzoic Acid; Adolescent; Aged; Feces; Female; Folic Acid; Glutamates; Humans; Male; Middle Aged; Neoplasms; para-Aminobenzoates; Tetrahydrofolates | 1982 |
Transport of folate compounds, pterins and adenine in L1210 mouse leukemia cells.
Topics: Adenine; Animals; Biological Transport; Energy Metabolism; Folic Acid; Leukemia L1210; Membranes; Methotrexate; Mice; Neoplasms; Pterins; Tetrahydrofolate Dehydrogenase | 1982 |
[Importance of active and passive prevention of cancer, arteriosclerosis and senility].
Topics: Adolescent; Adult; Aged; Amniocentesis; Amniotic Fluid; Arteriosclerosis; Ascorbic Acid; Child; Child, Preschool; Chromosome Aberrations; Dementia; Female; Folic Acid; Glutathione; Humans; Infant; Middle Aged; Mutagens; Neoplasms; Pregnancy; Tretinoin | 1982 |
Folate levels in human liver from autopsies in Canada.
Topics: Accidents; Adolescent; Adult; Age Factors; Aged; Canada; Cardiovascular Diseases; Child; Child, Preschool; Female; Fetal Death; Folic Acid; Humans; Infant; Infant, Newborn; Liver; Male; Middle Aged; Neoplasms; Pregnancy; Respiratory Tract Diseases; Sex Factors | 1980 |
[Various modes of folic acid deficiencies in neoplasms].
Topics: Animals; Folic Acid; Folic Acid Deficiency; Humans; Liver; Liver Neoplasms; Neoplasms; Neoplasms, Experimental; Rats | 1980 |
The effect of malignant disease on the metabolism of pteroylglutamic acid in man.
Topics: Carbon Radioisotopes; Folic Acid; Humans; Neoplasms; Tritium | 1980 |
Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications.
Topics: Adult; Antineoplastic Agents; Carcinoma; Carrier Proteins; Cell Line; Chorion; Fetus; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Kidney; Liver; Lung; Neoplasms; Poly A; Polymerase Chain Reaction; Receptors, Cell Surface; RNA; RNA, Messenger; Tumor Cells, Cultured | 1994 |
Folate receptor mediated DNA delivery into tumor cells: potosomal disruption results in enhanced gene expression.
Topics: Adenoviridae; Biological Transport, Active; Carrier Proteins; DNA, Recombinant; Drug Delivery Systems; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Therapy; Humans; Neoplasms; Receptors, Cell Surface; Serum Albumin, Bovine; Tumor Cells, Cultured | 1994 |
Re: Enigma of fluorouracil and levamisole.
Topics: Antimetabolites, Antineoplastic; Fluorouracil; Folic Acid; Humans; Leucovorin; Levamisole; Neoplasms | 1995 |
Suramin sodium: pronounced effects on methotrexate transport and anti-folate activity in cultured tumor cells.
Topics: Antineoplastic Agents; Biological Transport; Carrier Proteins; Cell Division; Drug Synergism; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Pyrimethamine; Receptors, Cell Surface; Suramin; Tumor Cells, Cultured | 1995 |
Classical and nonclassical furo[2,3-d]pyrimidines as novel antifolates: synthesis and biological activities.
Topics: AIDS-Related Opportunistic Infections; Animals; Folic Acid; Folic Acid Antagonists; Humans; Liver; Methotrexate; Molecular Structure; Neoplasms; Pneumocystis; Rats; Recombinant Proteins; Structure-Activity Relationship; Thymidylate Synthase; Toxoplasma; Tumor Cells, Cultured | 1994 |
Re: "Oncology drug discovery and clinical trial testing: who's listening?".
Topics: Animals; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Folic Acid; Humans; Kidney; Mice; Neoplasms; Quinazolines; Thymidylate Synthase | 1994 |
Micronutrients and cancer: time for action?
Topics: Antioxidants; Dietary Fats; Dietary Fiber; Folic Acid; Humans; Neoplasms; Vitamins | 1993 |
Folic acid as a cancer-preventing agent.
Topics: Animals; Anticarcinogenic Agents; Case-Control Studies; Chromosome Fragility; Cocarcinogenesis; Diet; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Global Health; Humans; Mice; Neoplasms; Neoplasms, Experimental; Prospective Studies; Rats; Vegetables | 1995 |
[Folic acid deficiency, cancer and congenital abnormalities].
Topics: Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Humans; Neoplasms; Pregnancy | 1996 |
[Folic acid deficiency, cancer and congenital abnormalities].
Topics: Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Humans; Neoplasms; Pregnancy | 1996 |
The role of dietary folate in modulation of folate receptor expression, folylpolyglutamate synthetase activity and the efficacy and toxicity of lometrexol.
Topics: Acyltransferases; Animals; Carrier Proteins; Diet; Enzyme Inhibitors; Folate Receptors, GPI-Anchored; Folic Acid; Hydroxymethyl and Formyl Transferases; Kidney; Liver; Mice; Neoplasms; Peptide Synthases; Phosphoribosylglycinamide Formyltransferase; Polyglutamic Acid; Protein Binding; Receptors, Cell Surface; Tetrahydrofolates; Tumor Cells, Cultured | 1996 |
Reduced folate carrier gene (RFC1) expression and anti-folate resistance in transfected and non-selected cell lines.
Topics: Antineoplastic Agents; Carrier Proteins; Drug Resistance, Neoplasm; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Neoplasms; Reduced Folate Carrier Protein; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1997 |
Relevance of tumoral folylpolyglutamate synthetase and reduced folates for optimal 5-fluorouracil efficacy: experimental data.
Topics: Antidotes; Antimetabolites, Antineoplastic; Biopsy; Drug Screening Assays, Antitumor; Drug Synergism; Female; Fluorouracil; Folic Acid; Humans; Leucovorin; Neoplasms; Peptide Synthases; Tumor Cells, Cultured | 1997 |
Serum folate and chronic disease risk: findings from a cohort of United States adults.
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Chronic Disease; Cohort Studies; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasms; Risk Factors; United States | 1998 |
Workshop on Folate, B12, and Choline. Sponsored by the Panel on Folate and other B vitamins of the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine, Washington, D.C., March 3-4,
Topics: Biological Availability; Biomarkers; Cardiovascular Diseases; Choline; Congenital Abnormalities; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Male; Neoplasms; Neural Tube Defects; Nutrition Policy; Nutritional Status; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Ambulant photodynamic therapy of superficial malignomas with 5-ALA in combination with folic acid and use of noncoherent light.
Topics: Administration, Topical; Ambulatory Care; Aminolevulinic Acid; Folic Acid; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents | 1999 |
Folate-targeted enzyme prodrug cancer therapy utilizing penicillin-V amidase and a doxorubicin prodrug.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antineoplastic Agents; Doxorubicin; Drug Carriers; Drug Screening Assays, Antitumor; Folic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Neoplasms; Penicillin Amidase; Prodrugs; Tumor Cells, Cultured | 1999 |
[Nutrition, genetic polymorphism, and cancer].
Topics: Colorectal Neoplasms; DNA; DNA Repair; Folic Acid; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Nutritional Physiological Phenomena; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Tetrahydrofolates; Thymidine; Uridine | 2000 |
Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene.
Topics: Adult; Aged; DNA Methylation; Female; Folic Acid; Homozygote; Humans; Leukocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic | 2000 |
Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Colonic Neoplasms; Fluorouracil; Folic Acid; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leucovorin; Lung Neoplasms; Membrane Proteins; Membrane Transport Proteins; Mice; Multienzyme Complexes; Neoplasms; Peptide Synthases; Reduced Folate Carrier Protein; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured | 2000 |
Folate, DNA methylation, and gene expression: factors of nature and nurture.
Topics: Congenital Abnormalities; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Humans; Neoplasms | 2000 |
Folate gains momentum as a vehicle for drug delivery.
Topics: Animals; Antineoplastic Agents; Contrast Media; Folic Acid; Genetic Therapy; Humans; Neoplasms; Pharmaceutical Vehicles; Radionuclide Imaging | 2000 |
Folic acid: miscarriages, anomalies, thromboses, cancers.
Topics: Adolescent; Adult; Alcoholism; Child; Child, Preschool; Congenital Abnormalities; Diet; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Pregnancy; Risk Factors; Thrombosis | 2001 |
Genetic aspects of nutrition and toxicology: report of a workshop.
Topics: Aging; Animals; Diet; Dietary Fats, Unsaturated; Disease Models, Animal; Folic Acid; Gene Expression Regulation; Humans; Neoplasms; Nutritional Physiological Phenomena; Toxicology; Zinc | 2001 |
Factors explaining the difference of total homocysteine between men and women in the European Investigation Into Cancer and Nutrition Potsdam study.
Topics: Adult; Age Factors; Aged; Analysis of Variance; Body Mass Index; Cohort Studies; Female; Folic Acid; Germany; Gonadal Steroid Hormones; Homocysteine; Humans; Linear Models; Male; Middle Aged; Neoplasms; Nutritional Physiological Phenomena; Sex Factors; Vitamin B 12 | 2001 |
Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with diet.
Topics: Body Mass Index; Diet; Dietary Fats; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Neoplasms; Pyridoxine; Reference Values; Risk Factors; S-Adenosylhomocysteine; S-Adenosylmethionine | 2001 |
Food labeling: health claims and labeling statements; dietary fiber and cancer; antioxidant vitamins and cancer; omega-3 fatty acids and coronary heart disease; folate and neural tube defects; revocation. Food and Drug Administration, HHS. Final rule.
Topics: Antioxidants; Dietary Fiber; Dietary Supplements; Fatty Acids, Omega-3; Folic Acid; Food Labeling; Heart Diseases; Humans; Neoplasms; Neural Tube Defects; United States; United States Food and Drug Administration | 2000 |
What 2nd year medical students at the University of Mississippi Medical Center know about disease prevention.
Topics: Academic Medical Centers; Adult; Aged; Body Mass Index; Data Collection; Diabetes Mellitus; Education, Medical; Exercise; Female; Folic Acid; Humans; Male; Middle Aged; Mississippi; Neoplasms; Neural Tube Defects; Pregnancy; Preventive Medicine; Risk Factors; Smoking; Students, Medical | 2002 |
Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors.
Topics: Animals; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescein; Folic Acid; Haptens; Immunoglobulin G; Immunotherapy; Interferon-alpha; Interferon-gamma; Interleukin-2; Kinetics; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Models, Chemical; Neoplasms; Time Factors; Tumor Cells, Cultured | 2002 |
Folate-targeted gene transfer in vivo.
Topics: Animals; Folic Acid; Gene Targeting; Gene Transfer Techniques; Genetic Vectors; In Vitro Techniques; Liposomes; Lung; Mice; Neoplasms; Polyethylene Glycols | 2002 |
Severe folate deficiency impairs natural killer cell-mediated cytotoxicity in rats.
Topics: Adjuvants, Immunologic; Animals; Cytotoxicity, Immunologic; Folic Acid; Folic Acid Deficiency; Homocysteine; Killer Cells, Natural; Liver; Lymphocyte Subsets; Male; Neoplasms; Rats; Rats, Sprague-Dawley | 2002 |
Schizophrenia, epilepsy, cancer, methionine, and folate metabolism. Pathogenesis of schizophrenia.
Topics: Anticonvulsants; Epilepsy; Folic Acid; Folic Acid Antagonists; Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; Schizophrenia | 1975 |
Pterin-6-aldehyde, a cancer cell catabolite: identification and application in diagnosis and treatment of human cancer.
Topics: Adolescent; Adult; Aged; Cell Line; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasms; Pterins; Spectrometry, Fluorescence | 1977 |
Toward improved selectivity in cancer chemotherapy: the Richard and Hinda Rosenthal Foundation Award Lecture.
Topics: Animals; Antineoplastic Agents; Carboxypeptidases; Drug Resistance; Drug Therapy, Combination; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Leucovorin; Methotrexate; Neoplasms; Uracil Nucleotides | 1979 |
[Method for determination of methotrexate in biological materials].
Topics: Body Fluids; Folic Acid; Humans; Leucovorin; Methods; Methotrexate; Neoplasms; Tetrahydrofolate Dehydrogenase | 1979 |
[The fundamental evaluation and clinical application of 3H-folic acid assay kit (author's transl)].
Topics: Adult; Aged; Binding, Competitive; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasms; Radioligand Assay; Reagent Kits, Diagnostic | 1979 |
[Metabolism of aminoanalogues of folate (author's transl)].
Topics: Acetylation; Amino Acids; Animals; Deamination; Folic Acid; Folic Acid Antagonists; Glutamates; Hydroxylation; Methotrexate; Mice; Neoplasms | 1977 |
Elevated serum levels of unsaturated folate binding protein: clinical correlates in a general hospital population.
Topics: Adult; Aged; Carrier Proteins; Folic Acid; Humans; Liver Diseases; Middle Aged; Neoplasm Metastasis; Neoplasms | 1978 |
Clinical significance of a high mean corpuscular volume in nonanemic patients.
Topics: Adolescent; Adult; Aged; Alcoholism; Anemia; Erythrocyte Volume; Erythrocytes; Female; Folic Acid; Hemoglobins; Humans; Liver Diseases; Lung Diseases, Obstructive; Male; Middle Aged; Neoplasms; Vitamin B 12 | 1977 |
Cancer chemotherapy: What drugs are available.
Topics: Antibiotics, Antineoplastic; Doxorubicin; Folic Acid; History, 19th Century; Hodgkin Disease; Humans; Leukemia; Neoplasms; Nitrogen Mustard Compounds; Vinca Alkaloids | 1976 |
Oncology drug discovery and clinical trial testing: who's listening?
Topics: Antineoplastic Agents; Clinical Trials as Topic; Drug Evaluation; Fluorouracil; Folic Acid; Humans; Neoplasms; Quinazolines; Thymidylate Synthase | 1992 |
l-folinic acid versus d,l-folinic acid in rescue of high-dose methotrexate therapy in children.
Topics: Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Female; Folic Acid; Humans; Infant; Leucovorin; Male; Methotrexate; Neoplasms; Stereoisomerism | 1992 |
No difference in expression of chromosomal fragile sites in patients with solid malignant tumours and normal controls.
Topics: Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; Folic Acid; Genetic Predisposition to Disease; Humans; Lymphocytes; Neoplasms; Single-Blind Method | 1990 |
Epidemiological screening for potentially carcinogenic drugs.
Topics: Barbiturates; Breast Neoplasms; Carcinogens; Diazepam; Dose-Response Relationship, Drug; Erythromycin; Folic Acid; Humans; Information Systems; Lung Neoplasms; Multiple Myeloma; Neoplasms; Product Surveillance, Postmarketing; Vitamin E | 1990 |
Modulation of fluoropyrimidines by folates. Workshop on new frontiers in medical oncology. Erice, Italy, March 20-23, 1989. Proceedings.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Folic Acid; Humans; Neoplasms | 1990 |
Biochemical and pharmacologic rationale for high-dose methotrexate.
Topics: Biological Transport; Biotransformation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Folic Acid; Humans; Leucovorin; Methotrexate; Neoplasms; Polyglutamic Acid; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 1987 |
Development of an assay for the estimation of N10-propargyl-5,8-dideazafolic acid polyglutamates in tumor cells.
Topics: Animals; Chromatography, High Pressure Liquid; Folic Acid; Leukemia L1210; Mice; Neoplasms; Peptides; Polyglutamic Acid; Quinazolines; Thymidylate Synthase | 1988 |
Screening prescription drugs for possible carcinogenicity: eleven to fifteen years of follow-up.
Topics: Anti-Bacterial Agents; Atropa belladonna; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Erythromycin; Esophageal Neoplasms; Folic Acid; Follow-Up Studies; Gastrointestinal Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neomycin; Neoplasms; Phenylbutazone; Piperidones; Plants, Medicinal; Plants, Toxic; Polymyxin B; Propantheline; Secobarbital; Sulfathiazoles; Vitamins | 1989 |
A phase I evaluation of N10-propargyl-5,8-dideazafolic acid.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Evaluation; Folic Acid; Humans; Middle Aged; Neoplasms; Quinazolines | 1988 |
Phase I study of the antifolate N10-propargyl-5,8-dideazafolic acid, CB 3717.
Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Creatinine; Drug Evaluation; Fatigue; Female; Folic Acid; Folic Acid Antagonists; Humans; Male; Middle Aged; Neoplasms; Quinazolines; Thymidylate Synthase | 1988 |
On the role of folate deficiency in cancer therapy.
Topics: Folic Acid; Folic Acid Deficiency; Humans; Methotrexate; Neoplasms | 1988 |
Development of folates and folic acid antagonists in cancer chemotherapy.
Topics: Folic Acid; Folic Acid Antagonists; Humans; Neoplasms | 1987 |
[Current status of the use of vitamins (A, E, C, D), folates and selenium in the chemoprevention and treatment of malignant tumors].
Topics: Ascorbic Acid; Folic Acid; Humans; Neoplasms; Retinoids; Selenium; Skin Diseases; Vitamin A; Vitamin D; Vitamin E; Vitamins | 1987 |
Evaluation of pteridines in patients with different tumors.
Topics: Adult; Aged; Erythrocytes; Folic Acid; Humans; Leukocytes; Middle Aged; Neoplasms; Pteridines | 1987 |
The role of vitamin B12 and folate in carcinogenesis.
Topics: Carcinogens; DNA Replication; Folic Acid; Folic Acid Deficiency; Humans; Neoplasms; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Role of vitamin B12 and folate deficiencies in carcinogenesis.
Topics: Animals; Carcinogens; Diet; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Neoplasms; Neoplasms, Experimental; Vitamin B 12 Deficiency | 1986 |
Nucleophilic targets in carcinogenesis, mutagenesis and chemotherapy of cancer.
Topics: Alkylating Agents; Antineoplastic Agents; Carcinogens; Folic Acid; Kinetics; Neoplasms; Nitrosourea Compounds; Quantum Theory; Spectrophotometry, Ultraviolet; Tetrahydrofolates | 1987 |
A phase I evaluation of the quinazoline antifolate thymidylate synthase inhibitor, N10-propargyl-5,8-dideazafolic acid, CB3717.
Topics: Acetylglucosaminidase; Acid Phosphatase; Alanine Transaminase; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Folic Acid; Folic Acid Antagonists; Glomerular Filtration Rate; Hematologic Diseases; Hyperbilirubinemia; Kidney Diseases; Leucyl Aminopeptidase; Neoplasms; Quinazolines; Skin Diseases; Thymidylate Synthase | 1986 |
Reduced citrovorum factor rescue for high-dose methotrexate therapy in childhood malignancies.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Bone Marrow; Child; Child, Preschool; Drug Therapy, Combination; Female; Folic Acid; Humans; Infusions, Parenteral; Leucovorin; Leukocyte Count; Male; Methotrexate; Neoplasms; Time Factors | 1985 |
Analysis of urinary fluorescent compounds for cancer detection.
Topics: Chromatography, High Pressure Liquid; Fluorescence; Folic Acid; Humans; Neoplasms | 1985 |
Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
Topics: Aminopterin; Animals; Cells, Cultured; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Mice; Neoplasms; Pteroylpolyglutamic Acids; Tumor Stem Cell Assay | 1985 |
Folate and iron metabolism in patients with tumors and inflammations.
Topics: Anorexia; Body Composition; Folic Acid; Humans; Inflammation; Iron; Macrophage Activation; Macrophages; Models, Biological; Neoplasms | 1985 |
Secondary anemia (XV) and reticuloendothelial uptake in cancer.
Topics: Adult; Aged; Alpha-Globulins; Anemia; Beta-Globulins; Blood Sedimentation; Folic Acid; Gold Colloid, Radioactive; Humans; Iodine Radioisotopes; Iron Radioisotopes; Middle Aged; Mononuclear Phagocyte System; Neoplasms; Rose Bengal | 1974 |
Excretion of formiminoglutamic acid in reticulosis and carcinoma.
Topics: Anemia, Macrocytic; Blood Chemical Analysis; FIGLU Test; Folic Acid; Humans; Leukemia; Lymphatic Diseases; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasms; Urine; Vitamin B 12 | 1966 |
The variability of individual tolerance to methotrexate in cancer patients.
Topics: Adult; Age Factors; Aged; Alopecia; Blood Urea Nitrogen; Body Weight; Chemical and Drug Induced Liver Injury; Conjunctivitis; Creatinine; Diarrhea; Drug Eruptions; Folic Acid; Humans; Injections, Intravenous; Leukopenia; Methotrexate; Middle Aged; Nausea; Neoplasms; Serum Albumin; Stomatitis; Thrombocytopenia; Time Factors; Vomiting | 1971 |
"Induction" of dihydrofolate reductase: purification and properties of the "induced" human erythrocyte and leukocyte enzyme and normal bone marrow enzyme.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromatography; Enzyme Activation; Enzyme Induction; Erythrocytes; Folic Acid; Humans; Hydrogen-Ion Concentration; Immune Sera; Leukemia L1210; Leukocytes; Methotrexate; Molecular Weight; NAD; NADP; Neoplasms; Protein Denaturation; Tetrahydrofolate Dehydrogenase | 1970 |
[Folate status and urinary folate excretion in malignant disease].
Topics: Aged; Breast Neoplasms; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasms; Prostatic Neoplasms | 1974 |
Serum folate levels in malignant disorders.
Topics: Adolescent; Adult; Anemia; Child; Female; Folic Acid; Hemoglobins; Humans; Leukemia; Male; Middle Aged; Neoplasms | 1974 |
The biochemist's outlook on cancer research.
Topics: Aerobiosis; Animals; Antineoplastic Agents; Biochemistry; Carbon Radioisotopes; Cell Transformation, Neoplastic; DNA Replication; England; Folic Acid; Folic Acid Antagonists; Glycolysis; History, 20th Century; Humans; Isotope Labeling; Lactates; Leukemia; Mice; Neoplasms; Research; Tetrahydrofolates; Thymidine; Thymidylate Synthase; Thymine; United States | 1973 |
The pathogenesis of folic acid deficiency in man.
Topics: Adolescent; Adult; Aged; Alcoholism; Anemia, Macrocytic; Animals; Anticonvulsants; Celiac Disease; Child; Diet; Female; Folic Acid; Folic Acid Deficiency; Hematologic Diseases; Humans; Inflammation; Liver; Male; Metabolic Diseases; Methotrexate; Neoplasms; Pregnancy | 1974 |
Plasma levels of methotrexate in cancer patients as studied by an improved spectrophotofluorometric method.
Topics: Adult; Aged; Chromatography, Ion Exchange; Creatinine; Cytarabine; Diatrizoate; Female; Folic Acid; Heparin; Humans; Hydrogen-Ion Concentration; Male; Methods; Methotrexate; Middle Aged; Neoplasms; Oxidation-Reduction; Potassium Permanganate; Spectrometry, Fluorescence; Time Factors; Triamterene; Tritium; Tryptophan; Tungsten | 1974 |
Small intestinal function in malignant neoplasia.
Topics: Adult; Aged; Biopsy; Celiac Disease; Feces; Female; Folic Acid; Gastrointestinal Neoplasms; Humans; Immunoglobulin A; Intestine, Small; Jejunum; Lung Neoplasms; Lymphatic Metastasis; Malabsorption Syndromes; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Schilling Test; Sulfobromophthalein; Tritium; Xylose | 1972 |
Drugs used in radiotherapy.
Topics: Adenine; Alkylating Agents; Analgesics; Anemia; Anti-Bacterial Agents; Antiemetics; Antimetabolites; Antineoplastic Agents; Drug Therapy; Expectorants; Folic Acid; Humans; Mercaptopurine; Methotrexate; Neoplasms; Pharmaceutical Preparations; Radiotherapy; Steroids; Tranquilizing Agents; Vitamins | 1972 |
Quantitative aspects of the binding of folic acid by folate antiserum.
Topics: Animals; Antibodies; Cell Division; Coenzymes; Extracellular Space; Folic Acid; Folic Acid Antagonists; Guinea Pigs; Haptens; Immune Sera; Immunization; Neoplasms; Protein Binding; Rabbits; Serum Albumin, Bovine | 1971 |
Irreversible enzyme inhibitors. LXXXVI. Hydrophobic bonding to dihydrofolic reductase. 8. Substituted-1-aryl-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazines.
Topics: Aminopterin; Chemistry, Organic; Enzymes; Folic Acid; Neoplasms; Organic Chemistry Phenomena; Tetrahydrofolate Dehydrogenase; Triazines | 1967 |
Intestinal structure and function in neoplastic disease.
Topics: Adult; Aged; Biopsy; Body Weight; Folic Acid; Hemoglobins; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Jejunum; Middle Aged; Neoplasms; Serum Albumin; Vitamin B 12; Xylose | 1969 |
Clinical and experimental evaluation of urinary histidine derivatives as an index of folic acid metabolism. II. The observation in neoplastic diseases with or without methotrexate administration.
Topics: Adult; Aged; Animals; Blood Cell Count; Blood Platelets; Dogs; Female; FIGLU Test; Folic Acid; Histidine; Humans; Leukocyte Count; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasms | 1969 |
[Investigations of formiminoglutamic acid excreted in urine following treatment with trimethoprim alone and with trimethoprim and a sulfonamide].
Topics: Adolescent; Adult; Aged; Anemia; Anti-Infective Agents; Female; FIGLU Test; Folic Acid; Folic Acid Antagonists; Glutamates; Histidine; Humans; Male; Middle Aged; Neoplasms; Pyrimidines; Sulfamethoxazole | 1969 |
A haematological study of 500 elderly females.
Topics: Age Factors; Aged; Anemia; Anemia, Hypochromic; Arthritis, Rheumatoid; Blood Chemical Analysis; Blood Proteins; Blood Sedimentation; Bronchitis; England; Feces; Female; Folic Acid; Folic Acid Deficiency; Health Surveys; Hematologic Diseases; Hemoglobins; Hospitalization; Humans; Iron; Middle Aged; Neoplasms; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
Studies of folate deficiency in patients with neoplastic diseases.
Topics: Adult; Aged; Female; Folic Acid; Folic Acid Deficiency; Humans; Leukocytes; Liver; Male; Middle Aged; Neoplasms; Time Factors | 1970 |
Some aspects of the role of vitamin B 12 and folic acid in DNA-thymidine sy nthesis in a neoplastic C3H mouse cell strain.
Topics: Adenine; Animals; Carbon Isotopes; Cell Line; Chromatography, Paper; Culture Media; Culture Techniques; Deoxyuridine; DNA, Neoplasm; Folic Acid; Formates; Hydroxocobalamin; Mice; Neoplasms; Stimulation, Chemical; Thymidine; Vitamin B 12 | 1971 |
Some considerations of folic acid antagonists.
Topics: Chemical Phenomena; Chemistry; Folic Acid; Folic Acid Antagonists; Methotrexate; Neoplasms | 1971 |
[FIGLU (formimino-glutamic acid): urinary excretion in malignant neoplasms in childhood].
Topics: Adolescent; Anemia; Antineoplastic Agents; Child; Child, Preschool; Female; FIGLU Test; Folic Acid; Humans; Infant; Leukemia; Liver Diseases; Male; Neoplasms; Nutrition Disorders | 1967 |
[On the determination of folic acid activity of human blood in controls and in different pathological states].
Topics: Adolescent; Adult; Anemia, Hypochromic; Anemia, Pernicious; Bone Marrow Diseases; Diabetes Mellitus; Erythrocytes; Female; Folic Acid; Hematologic Diseases; Humans; Leukemia; Liver Cirrhosis; Lymphatic Diseases; Male; Methods; Middle Aged; Neoplasms; Polycythemia Vera; Vitamin B 12 Deficiency | 1969 |
[Low folic acid diet in malignant tumors].
Topics: Choriocarcinoma; Diet Therapy; Female; Folic Acid; Humans; Leukemia; Neoplasm Metastasis; Neoplasms; Pregnancy | 1969 |
[Does folic acid encourage tumor growth?].
Topics: Folic Acid; Folic Acid Antagonists; Humans; Leukemia; Neoplasms | 1969 |
[The folic acid test for the early diagnosis of malignant neoplasms].
Topics: Folic Acid; Humans; In Vitro Techniques; Neoplasms; Urine | 1965 |
Metabolic studies on folic acid in malignancy.
Topics: Blood; Folic Acid; Humans; Middle Aged; Neoplasms; Urine | 1966 |