Page last updated: 2024-08-17

folic acid and BH4 Deficiency

folic acid has been researched along with BH4 Deficiency in 32 studies

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (40.63)	18.7374
1990's	2 (6.25)	18.2507
2000's	5 (15.63)	29.6817
2010's	7 (21.88)	24.3611
2020's	5 (15.63)	2.80

Authors

Authors	Studies
Kasyanov, ED; Kostina, OV; Mazo, GE; Piatoikina, AS; Rukavishnikov, GV; Semennov, IV; Verbitskaya, EV; Zhilyaeva, TV	1
Alvarez, JA; Cui, X; Ramakrishnan, U; Schoen, MS; Singh, RH; Ziegler, TR	1
Ahmadzadeh, M; Alaei, M; Eini-Zinab, H; Mohammadpour-Ahranjani, B; Namkhah, Z; Rastgoo, S; Sohrab, G	1
Belsten, J; Heales, S; Jones, H; Pope, S; Werring, DJ	1
Akış, M; Arslan, N; Işık, İ; İşlekel, H; Kant, M; Kısa, PT; Köse, E	1
Aldámiz-Echevarría, L; Andrade, F; Couce, ML; Llarena, M; López-Suárez, O	1
Baumgartner, MR; Bollhalder, S; Gerber, P; Hochuli, M; Refardt, J; Thierer, C	1
Li, J; Wang, C	1
Heales, SJ; Kurian, MA; Ng, J	1
Chakrapani, A; Daly, A; Evans, S; MacDonald, A; MacDonald, J; Preece, MA; Santra, S; Vijay, S	1
Benáková, H; Haňková, Z; Jarkovský, J; Konečná, P; Mikušková, A; Procházková, D; Vinohradská, H	1
Gładysz, D; Hozyasz, KK; Korycińska-Chaaban, D; Nowacka, M; Przybylska-Kruszewska, A; Zielińska, M; Żółkowska, J	1
Green, A; Hall, K; Leeming, R; Lucock, M; MacDonald, A; Rylance, G; Yates, Z	1
Karikas, GA; Papakonstantinou, E; Schulpis, KH	1
Artuch, R; Brandi, N; Campistol, J; Colomé, C; Lambruschini, N; Sierra, C; Vilaseca, MA	1
KNAPP, A; MULLER, R	1
McGEER, EG; TISCHLER, B	1
Hvas, AM; Nexo, E; Nielsen, JB	1
Dhondt, JL	1
Luke, B	1
Concolino, D; Moricca, MT; Parlato, G; Rivalta, L; Strisciuglio, P	1
Cleary, MA; Lam, WK; Robinson, M; Walter, JH; White, FJ; Wraith, E	1
Woolf, LI	1
Cooper, BA	1
Erbe, RW	1
Butler, IJ; Irons, M; Kaufman, S; Langlais, PJ; Levy, HL; Milstien, S; O'Flynn, ME; Stack, CV	1
Bracco, G; Cotton, RG; Ferraris, S; Guardamagna, O; Niederwieser, A; Ponzone, A	1
Howells, DW; Hyland, K; Smith, I	1
Hyland, K; Kendall, B; Smith, I	1
Hages, M; Pietrzik, K	1
Milne, MD	1
Carver, MJ; Copenhaver, JH; Schain, RJ	1

Reviews

7 review(s) available for folic acid and BH4 Deficiency

Article	Year
Clinical features and pharmacotherapy of childhood monoamine neurotransmitter disorders. Paediatric drugs, 2014, Volume: 16, Issue:4 Topics: Catecholamines; Child; Dopamine; Folic Acid; Humans; Nervous System Diseases; Neurotransmitter Agents; Phenylketonurias; Serotonin	2014
Tetrahydrobiopterin deficiencies: preliminary analysis from an international survey. The Journal of pediatrics, 1984, Volume: 104, Issue:4 Topics: Adjuvants, Pharmaceutic; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Biopterins; Female; Folic Acid; GTP Cyclohydrolase; Humans; Infant; Infant, Newborn; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Pteridines	1984
Maternal-fetal nutrition. Clinical obstetrics and gynecology, 1994, Volume: 37, Issue:1 Topics: Adult; Birth Weight; Body Height; Body Weight; Diet; Energy Intake; Female; Fetus; Folic Acid; Humans; Middle Aged; Neural Tube Defects; Nutritional Physiological Phenomena; Nutritional Requirements; Phenylketonurias; Pregnancy; Prenatal Care; Smoking; Weight Gain	1994
The dietary treatment of inborn errors of metabolism. The Proceedings of the Nutrition Society, 1976, Volume: 35, Issue:1 Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Anemia, Megaloblastic; Child; Female; Folic Acid; Galactosemias; Glutamate Decarboxylase; Homocystinuria; Humans; Infant; Infant, Newborn; Lactose Intolerance; Maple Syrup Urine Disease; Metabolism, Inborn Errors; Methylmalonic Acid; Phenylketonurias; Pregnancy; Vitamin B 12	1976
Megaloblastic anaemia and disorders affecting utilisation of vitamin B12 and folate in childhood. Clinics in haematology, 1976, Volume: 5, Issue:3 Topics: Adolescent; Adult; Anemia, Hemolytic; Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Pernicious; Biological Transport; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Female; Folic Acid; Folic Acid Deficiency; Homocystinuria; Humans; Infant; Intrinsic Factor; Malabsorption Syndromes; Male; Metabolism, Inborn Errors; Methionine; Methionine Adenosyltransferase; Orotic Acid; Phenylketonurias; Tetrahydrofolate Dehydrogenase; Transcobalamins; Vitamin B 12	1976
Inborn errors of folate metabolism (second of two parts). The New England journal of medicine, 1975, Oct-16, Volume: 293, Issue:16 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Child; Female; Folic Acid; Formates; Glutamates; Glycine; Humans; Hydrolases; Imines; Infant; Malabsorption Syndromes; Male; Metabolism, Inborn Errors; Methionine Adenosyltransferase; Methylenetetrahydrofolate Dehydrogenase (NADP); Phenylketonurias; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Transferases; Vitamin B 12	1975
Pteridines and mono-amines: relevance to neurological damage. Postgraduate medical journal, 1986, Volume: 62, Issue:724 Topics: Amines; Biopterins; Folic Acid; Humans; Nervous System; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pteridines	1986

Other Studies

25 other study(ies) available for folic acid and BH4 Deficiency

Article	Year
Tetrahydrobiopterin deficiency in schizophrenia: Biochemical and clinical aspects. Journal of psychiatric research, 2022, Volume: 153 Topics: C-Reactive Protein; Case-Control Studies; Folic Acid; Homocysteine; Humans; Phenylketonurias; Schizophrenia; Vitamin B 12	2022
Characterization of Choline Nutriture among Adults and Children with Phenylketonuria. Nutrients, 2022, Sep-29, Volume: 14, Issue:19 Topics: Adult; Child; Choline; Female; Folic Acid; Humans; Methionine; Nutrition Surveys; Phenylalanine; Phenylketonurias; Pregnancy; Vitamin B 12; Vitamins	2022
Growth and Nutritional Status of Phenylketonuric Children and Adolescents. BMC pediatrics, 2022, 11-17, Volume: 22, Issue:1 Topics: Adolescent; Child; Child, Preschool; Cholecalciferol; Cross-Sectional Studies; Female; Folic Acid; Humans; Iron; Nutritional Status; Obesity; Overweight; Phenylalanine; Phenylketonurias; Vitamin B 12; Vitamin D Deficiency	2022
Cerebrospinal fluid folate, ascorbate, and tetrahydrobiopterin deficiency in superficial siderosis: A new potential mechanism of neurological dysfunction? Journal of the neurological sciences, 2020, 07-15, Volume: 414 Topics: Ascorbic Acid; Folic Acid; Humans; Magnetic Resonance Imaging; Phenylketonurias; Siderosis	2020
Functional vitamin B12 deficiency in phenylketonuria patients and healthy controls: An evaluation with combined indicator of vitamin B12 status as a biochemical index. Annals of clinical biochemistry, 2020, Volume: 57, Issue:4 Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Acid; Phenylketonurias; Vitamin B 12; Vitamin B 12 Deficiency	2020
Influence of phenylketonuria's diet on dimethylated arginines and methylation cycle. Medicine, 2017, Volume: 96, Issue:27 Topics: Arginine; Biomarkers; Child; Chromatography, High Pressure Liquid; Creatinine; Cross-Sectional Studies; Female; Folic Acid; Homocysteine; Humans; Male; Mass Spectrometry; Methylation; Patient Compliance; Phenylketonurias; Severity of Illness Index; Vitamin B 12	2017
Effects of Inadequate Amino Acid Mixture Intake on Nutrient Supply of Adult Patients with Phenylketonuria. Annals of nutrition & metabolism, 2017, Volume: 71, Issue:3-4 Topics: Adolescent; Adult; Amino Acids; Cross-Sectional Studies; Diet; Dietary Fats; Dietary Proteins; Female; Folic Acid; Humans; Male; Middle Aged; Nutrients; Nutritional Status; Phenylketonurias; Prospective Studies; Selenium; Vitamin B 12; Young Adult	2017
Subacute onset leukodystrophy and visual-spatial disorders revealing phenylketonuria combined with homocysteinmia in adulthood: A case report. Medicine, 2018, Volume: 97, Issue:8 Topics: Folic Acid; Humans; Hyperhomocysteinemia; Leukoencephalopathies; Male; Mutation; Phenylketonurias; Vision Disorders; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Young Adult	2018
The micronutrient status of patients with phenylketonuria on dietary treatment: an ongoing challenge. Annals of nutrition & metabolism, 2014, Volume: 65, Issue:1 Topics: Adolescent; Amino Acids; Biomarkers; Child; Child, Preschool; Copper; Diet; Dietary Supplements; Female; Folic Acid; Humans; Infant; Longitudinal Studies; Male; Micronutrients; Nutritional Status; Phenylalanine; Phenylketonurias; Retrospective Studies; Selenium; Zinc	2014
Long-term treatment for hyperphenylalaninemia and phenylketonuria: a risk for nutritional vitamin B12 deficiency? Journal of pediatric endocrinology & metabolism : JPEM, 2015, Nov-01, Volume: 28, Issue:11-12 Topics: Adolescent; Adult; Child; Child, Preschool; Female; Folic Acid; Homocysteine; Humans; Incidence; Male; Middle Aged; Phenylketonurias; Prospective Studies; Risk; Risk Assessment; Transcobalamins; Vitamin B 12 Deficiency; Young Adult	2015
[High plasma folate in patients with phenylketonuria]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2016, Volume: 40, Issue:238 Topics: Child; Child, Preschool; Female; Folic Acid; Humans; Male; Phenylketonurias; Poland; Retrospective Studies	2016
The impact of phenylketonuria on folate metabolism. Molecular genetics and metabolism, 2002, Volume: 76, Issue:4 Topics: Biopterins; Chromatography, High Pressure Liquid; Coenzymes; Folic Acid; Homocysteine; Humans; Immunoassay; Phenylalanine; Phenylketonurias	2002
Homocysteine and other vascular risk factors in patients with phenylketonuria on a diet. Acta paediatrica (Oslo, Norway : 1992), 2002, Volume: 91, Issue:8 Topics: Child; Child, Preschool; Coronary Artery Disease; Diet, Protein-Restricted; Endothelin-1; Folic Acid; Homocysteine; Humans; Lipids; Nutrition Assessment; Phenylalanine; Phenylketonurias; Risk Factors; Vitamin B 12; Vitamin B 6	2002
Plasma thiols and their determinants in phenylketonuria. European journal of clinical nutrition, 2003, Volume: 57, Issue:8 Topics: Adolescent; Cross-Sectional Studies; Cysteine; Female; Folic Acid; Glutathione; Homocysteine; Humans; Male; Methionine; Phenylalanine; Phenylketonurias; Sulfhydryl Compounds; Vitamin B 12	2003
[On the induction of phenylketonuria in rats and its influencing by folic acid and other pteridine derivatives]. Ernahrungsforschung. Berichte und Mitteilungen, 1963, Volume: 8 Topics: Animals; Folic Acid; Phenylketonurias; Pteridines; Pterins; Rats	1963
Effects of folic acid on the phenylalanine tolerance test in phenylketonuria. Canadian Medical Association journal, 1962, Dec-22, Volume: 87 Topics: Antimetabolites; Child; Drug Tolerance; Folic Acid; Humans; Immune Tolerance; Phenylalanine; Phenylketonurias; Tyrosine	1962
Vitamin B12 and vitamin B6 supplementation is needed among adults with phenylketonuria (PKU). Journal of inherited metabolic disease, 2006, Volume: 29, Issue:1 Topics: Adolescent; Adult; Diet, Protein-Restricted; Female; Folic Acid; Homocysteine; Humans; Male; Phenylketonurias; Transcobalamins; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6; Vitamin B 6 Deficiency	2006
Normal serum levels of vitamin B12 and folic acid in children with phenylketonuria. European journal of pediatrics, 1995, Volume: 154, Issue:10 Topics: Child; Child, Preschool; Female; Folic Acid; Humans; Infant; Male; Phenylketonurias; Reference Values; Vitamin B 12	1995
Increased risk of vitamin B12 deficiency in patients with phenylketonuria on an unrestricted or relaxed diet. The Journal of pediatrics, 2000, Volume: 136, Issue:4 Topics: Adolescent; Adult; Child; Folic Acid; Follow-Up Studies; Humans; Neurologic Examination; Phenylketonurias; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency	2000
Folinic acid therapy in treatment of dihydropteridine reductase deficiency. The Journal of pediatrics, 1987, Volume: 110, Issue:1 Topics: 5-Hydroxytryptophan; Brain; Carbidopa; Drug Therapy, Combination; Female; Folic Acid; Humans; Infant; Infant, Newborn; Leucovorin; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias	1987
Two mutations of dihydropteridine reductase deficiency. Archives of disease in childhood, 1988, Volume: 63, Issue:2 Topics: Dihydropteridine Reductase; Female; Folic Acid; Humans; Infant; Male; Mutation; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Pterins; Tyrosine	1988
Clinical role of pteridine therapy in tetrahydrobiopterin deficiency. Journal of inherited metabolic disease, 1985, Volume: 8 Suppl 1 Topics: Amino Acid Metabolism, Inborn Errors; Biogenic Amines; Biopterins; Brain; Folic Acid; Folic Acid Deficiency; Humans; Infant; Phenylalanine; Phenylketonurias; Pteridines	1985
[Assessment of the folate supply in children with regard to cobalamin and iron maintenance. 3: Modification of the supply status by various diseases]. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1985, Volume: 55, Issue:3 Topics: Adolescent; Anticonvulsants; Celiac Disease; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Erythrocytes; Female; Folic Acid; Humans; Infant; Infections; Iron; Malabsorption Syndromes; Male; Phenylketonurias; Vitamin B 12	1985
Hereditary disorders of intestinal transport. Biomembranes, 1974, Volume: 4B, Issue:0 Topics: Abetalipoproteinemia; Acrodermatitis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Amylases; Amyloidosis; Carbohydrate Metabolism, Inborn Errors; Copper; Cystic Fibrosis; Cystinuria; Diarrhea; Fanconi Syndrome; Fats; Folic Acid; Fructose Intolerance; Glucosidases; Hartnup Disease; Humans; Intestinal Absorption; Lactose Intolerance; Magnesium; Malabsorption Syndromes; Monosaccharides; Pancreatitis; Phenylketonurias; Rickets; Vitamin B 12	1974
Effects of folic and folinic acids on the metabolism of phenylalanine in phenylketonuria. Metabolism: clinical and experimental, 1965, Volume: 14, Issue:12 Topics: Adolescent; Child; Female; Folic Acid; Humans; Lactates; Leucovorin; Male; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Urine	1965