folic acid has been researched along with Alloxan Diabetes in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.63) | 18.7374 |
| 1990's | 1 (2.63) | 18.2507 |
| 2000's | 9 (23.68) | 29.6817 |
| 2010's | 20 (52.63) | 24.3611 |
| 2020's | 7 (18.42) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, H; Liu, X | 1 |
| Cui, S; Fan, X; Gou, D; Pei, X; Peng, X; Song, C; Zhang, F; Zheng, X; Zhou, Y | 1 |
| Kuang, X; Li, D; Li, H; Li, K; Shao, X; Song, X; Wang, Y; Zhu, S | 1 |
| Ding, R; He, J; Li, Y; Shi, Y; Sun, K; Tao, Y; Wang, A; Yuan, R; Zhang, H; Zhao, Z | 1 |
| Advani, A; Advani, SL; Batchu, SN; Geldenhuys, L; Kabir, MDG; Kaur, H; Liu, Y; Poyah, P; Sedrak, P; Siddiqi, FS; Tennankore, KK; Tran, DT; Yerra, VG | 1 |
| Moradi Sarabi, M; Tabebordbar, M; Vakili, S; Zal, F; Zare, R | 1 |
| Chen, DG; Gong, YC; Li, YP; Li, ZL; Xiong, XY; Zhao, CW | 1 |
| Gao, Y; Huang, G; Li, M; Liu, H; Zheng, M; Zou, C | 1 |
| Gao, L; Li, J; Liu, J; Ma, L; Yu, A | 1 |
| Ameer, GA; Farha, OK; Huddleston, S; Li, P; Xiao, B; Xiao, J; Zhu, Y | 1 |
| Chen, YH; Hu, Y; Yu, H; Yuan, L; Yuan, MM; Zhang, XQ; Zhao, M; Zhou, J | 1 |
| Hou, J; Li, R; Liu, B; Luo, E; Qiao, Y; Tang, C; Wang, D; Yan, G; Zhu, B | 1 |
| Gong, YC; Li, YP; Li, ZL; Luo, YY; Xie, S; Xiong, XY | 1 |
| Al-Omar, MA; Al-Wasidi, AS; AlKahtani, HM; Bhat, MA; Naglah, AM; Refat, MS | 1 |
| Djuric, D; Gopcevic, K; Jakovljevic Uzelac, J; Labudovic Borovic, M; Mutavdzin, S; Stankovic, S | 2 |
| Fan, Y; Xiang, J; Xu, R; Zhan, M | 1 |
| Agrawal, AK; Harde, H; Jain, S; Thanki, K | 1 |
| Aktug, H; Erbas, O; Oltulu, F; Yilmaz, M | 1 |
| Kern, TS; Lee, CA; Liu, H; Tang, J | 1 |
| Mahdian, Z; Mostafavi-Pour, Z; Soghra, B; Zal, F; Zare, R | 1 |
| Angelini, GD; Hotston, M; Jeremy, JY; Persad, R; Shukla, N | 1 |
| Hayasaka, S; Murase, T; Murata, Y; Oiso, Y; Oyama, K; Sugimura, Y; Uchida, A | 1 |
| Angelini, GD; Bloor, J; Jeremy, JY; Shukla, N; Smith, FC | 1 |
| Givvimani, S; Metreveli, N; Mishra, PK; Tyagi, SC | 1 |
| Higa, R; Jawerbaum, A; Kurtz, M; Mazzucco, MB; Musikant, D; White, V | 1 |
| Cao, HF; Chi, BJ; Gui, SL; Guo, YG; Ma, HB; Qin, WB; Teng, F; Wang, SQ | 1 |
| Das, M; Godugu, C; Jain, AK; Jain, S; Rathi, VV | 1 |
| Fu, J; Hao, A; Ling, EA; Liu, Q; Liu, S; Wang, F; Yuan, Q; Zhang, Y; Zhao, S | 1 |
| Eriksson, UJ; Gäreskog, M; Wentzel, P | 1 |
| Eriksson, UJ; Wentzel, P | 1 |
| Garrow, TA; Hartz, CS; Nieman, KM; Schalinske, KL; Sparks, JD; Szegedi, SS | 1 |
| Eriksson, UJ; Wentzel, P; Zabihi, S | 1 |
| Batista-González, CM; Gallegos-Arreola, MP; Gómez-Meda, BC; Muñoz-Magallanes, T; Ramos-Ibarra, ML; Ramos-Valdés, C; Zamora-Perez, AL; Zúñiga-González, GM | 1 |
| Li, WH; Lin, ZQ; Wang, LX; Wu, TG | 1 |
| Angelini, GD; Jeremy, JY; Shukla, N | 1 |
| Kesavan, V; Noronha, JM; Pote, MS | 1 |
| Machii, B | 1 |
38 other study(ies) available for folic acid and Alloxan Diabetes
| Article | Year |
|---|---|
The palliative effects of folic acid on retinal microvessels in diabetic retinopathy via regulating the metabolism of DNA methylation and hydroxymethylation.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Endothelial Cells; Folic Acid; Humans; Male; Microvessels; Neovascularization, Pathologic; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Retina; Transcriptome; Zinc Fingers | 2021 |
Dual crosslinking of folic acid-modified pectin nanoparticles for enhanced oral insulin delivery.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Drug Carriers; Folic Acid; Insulin; Insulin, Regular, Human; Nanoparticles; Pectins; Rats | 2022 |
Synergistic Effects of Folic Acid and
Topics: Animals; Diabetes Mellitus, Experimental; Fatty Acids, Omega-3; Female; Folic Acid; Mice; Neural Tube Defects; Pregnancy | 2022 |
Folic acid-modified reverse micelle-lipid nanocapsules overcome intestinal barriers and improve the oral delivery of peptides.
Topics: Animals; Caco-2 Cells; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Exenatide; Folic Acid; Humans; Intestines; Lipids; Mice; Micelles; Nanocapsules; Nanoparticle Drug Delivery System; Peptides; Rats | 2023 |
Single cell G-protein coupled receptor profiling of activated kidney fibroblasts expressing transcription factor 21.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Diabetes Mellitus, Experimental; Doxorubicin; Fibroblasts; Fibrosis; Folic Acid; Humans; Kidney; Kidney Diseases; Mice; Mice, Inbred C57BL; Receptors, G-Protein-Coupled; Renal Insufficiency, Chronic; Transcription Factors; Ureteral Obstruction | 2023 |
Effect of folic acid and vitamin E on promoter DNA methylation and expression of TGF-β1, ESR-1 and CDH-1 in the uterus of STZ-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; DNA Methylation; Female; Folic Acid; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Uterus; Vitamin E | 2022 |
Study on the Influencing Factors of Hypoglycemic Effect of Folate Targeted Polymersomes Encapsulating Insulin.
Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Diabetes Mellitus, Experimental; Drug Carriers; Folic Acid; Humans; Hypoglycemic Agents; Insulin; Polyethylene Glycols; Rats | 2021 |
Folic Acid Reduces Tau Phosphorylation by Regulating PP2A Methylation in Streptozotocin-Induced Diabetic Mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; DNA (Cytosine-5-)-Methyltransferases; Folic Acid; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Male; Methylation; Mice; Phosphorylation; Protein Phosphatase 2; tau Proteins | 2017 |
eNOS Uncoupling: A Therapeutic Target For Ischemic Foot of Diabetic Rat.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Foot; Folic Acid; Ischemia; Male; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Tetrahydrofolate Dehydrogenase; Transfection; Vitamin B Complex | 2019 |
Copper Metal-Organic Framework Nanoparticles Stabilized with Folic Acid Improve Wound Healing in Diabetes.
Topics: Animals; Cell Line; Copper; Diabetes Mellitus, Experimental; Folic Acid; Humans; Metal-Organic Frameworks; Mice; Mice, Inbred C57BL; Nanoparticles; Wound Healing | 2018 |
Folic Acid Promotes Wound Healing in Diabetic Mice by Suppression of Oxidative Stress.
Topics: Animals; Diabetes Mellitus, Experimental; Folic Acid; Glutathione; Hydroxyproline; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Skin; Wound Healing | 2018 |
The Protective Effects of Enalapril Maleate and Folic Acid Tablets against Contrast-Induced Nephropathy in Diabetic Rats.
Topics: Animals; Apoptosis; Blood Urea Nitrogen; Contrast Media; Creatinine; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Combinations; Enalapril; Endothelial Cells; Folic Acid; Humans; Kidney; Kidney Diseases; Nitric Oxide; Oxidative Stress; Rats | 2018 |
Targeted folate-conjugated pluronic P85/poly(lactide-co-glycolide) polymersome for the oral delivery of insulin.
Topics: Administration, Oral; Animals; Caco-2 Cells; Cell Proliferation; Diabetes Mellitus, Experimental; Fluorescein-5-isothiocyanate; Folic Acid; Humans; Insulin; Lactic Acid; Polyglactin 910; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats | 2018 |
Synthesis of a vanadyl (IV) folate complex for the treatment of diabetes: spectroscopic, structural, and biological characterization.
Topics: Animals; Diabetes Mellitus, Experimental; Electron Spin Resonance Spectroscopy; Folic Acid; Hypoglycemic Agents; Male; Molecular Structure; Organometallic Compounds; Particle Size; Rats; Spectrophotometry, Infrared; Streptozocin; Surface Properties; Thermodynamics; Vanadates | 2019 |
The effect of folic acid administration on cardiac tissue matrix metalloproteinase activity and hepatorenal biomarkers in diabetic rats
Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Folic Acid; Kidney; Liver; Male; Matrix Metalloproteinases; Myocardium; Rats; Rats, Wistar | 2019 |
The Effects of Folic Acid Administration on Cardiac Oxidative Stress and Cardiovascular Biomarkers in Diabetic Rats.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Folic Acid; Lipid Peroxidation; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 2019 |
[Effect of the folic acid and vitamin B2 on the diabetes mellitus rats with diabetic nephropathy].
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Folic Acid; Glutathione Peroxidase; Male; Rats; Rats, Sprague-Dawley; Riboflavin | 2012 |
Improved stability and antidiabetic potential of insulin containing folic acid functionalized polymer stabilized multilayered liposomes following oral administration.
Topics: Administration, Oral; Animals; Caco-2 Cells; Diabetes Mellitus, Experimental; Drug Delivery Systems; Drug Stability; Folic Acid; Humans; Insulin; Liposomes; Male; Polymers; Rats; Rats, Sprague-Dawley | 2014 |
Neuroprotective effects of folic acid on experimental diabetic peripheral neuropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Female; Folic Acid; Lipid Peroxidation; Malondialdehyde; Nerve Growth Factors; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2016 |
Metanx and early stages of diabetic retinopathy.
Topics: Animals; Contrast Sensitivity; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Folic Acid; I-kappa B Proteins; Intercellular Adhesion Molecule-1; Leukostasis; Male; Mice; Mice, Inbred C57BL; Pyridoxal Phosphate; Retinal Vessels; Superoxides; Vitamin B 12; Vitamin B Complex | 2015 |
Combination of vitamin E and folic acid ameliorate oxidative stress and apoptosis in diabetic rat uterus.
Topics: Animals; Apoptosis; Caspase 3; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Female; Folic Acid; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Uterus; Vitamin E | 2014 |
The administration of folic acid improves erectile function and reduces intracavernosal oxidative stress in the diabetic rabbit.
Topics: Animals; Antioxidants; Blotting, Western; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Erectile Dysfunction; Folic Acid; Male; Oxidative Stress; Penile Erection; Rabbits; Treatment Outcome; Vasodilator Agents | 2009 |
Folic acid prevents congenital malformations in the offspring of diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Congenital Abnormalities; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Embryo, Mammalian; Female; Fetal Weight; Folic Acid; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome; Streptozocin | 2009 |
Folic acid administration reduces neointimal thickening, augments neo-vasa vasorum formation and reduces oxidative stress in saphenous vein grafts from pigs used as a model of diabetes.
Topics: Analysis of Variance; Animals; Blood Glucose; Carotid Arteries; Diabetes Mellitus, Experimental; Endothelium, Vascular; Folic Acid; Oxidative Stress; Saphenous Vein; Statistics, Nonparametric; Swine; Tunica Intima; Vasa Vasorum; Vascular Patency | 2010 |
Attenuation of beta2-adrenergic receptors and homocysteine metabolic enzymes cause diabetic cardiomyopathy.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Cardiomyopathies; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Diabetes Mellitus, Experimental; Folic Acid; Glucose; Glucose Transporter Type 4; Heart Failure; Homocysteine; Hyperglycemia; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardial Contraction; Myocytes, Cardiac; Receptors, Adrenergic, beta-2; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2010 |
Folic acid and safflower oil supplementation interacts and protects embryos from maternal diabetes-induced damage.
Topics: Animals; Congenital Abnormalities; Diabetes Mellitus, Experimental; Dietary Supplements; Embryo, Mammalian; Embryonic Development; Female; Fetal Resorption; Folic Acid; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nitric Oxide; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Safflower Oil | 2012 |
[Correlation of homocysteine in plasma with NOS and endogenous CO in the penile corpus cavernosum of type 2 diabetic rats].
Topics: Animals; Carbon Monoxide; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Folic Acid; Homocysteine; Insulin; Male; Nitric Oxide Synthase; Penis; Rats; Rats, Wistar; Vitamin B 12 | 2012 |
Folate-decorated PLGA nanoparticles as a rationally designed vehicle for the oral delivery of insulin.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Carriers; Folic Acid; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley | 2012 |
Folic acid supplementation changes the fate of neural progenitors in mouse embryos of hyperglycemic and diabetic pregnancy.
Topics: Animals; Apoptosis; Blotting, Western; Cell Differentiation; Cell Proliferation; Diabetes Mellitus, Experimental; Dietary Supplements; Doublecortin Domain Proteins; Embryo, Mammalian; Female; Folic Acid; Hyperglycemia; In Situ Nick-End Labeling; Mice; Microtubule-Associated Proteins; Neural Stem Cells; Neuropeptides; Pregnancy | 2013 |
Folic acid supplementation diminishes diabetes- and glucose-induced dysmorphogenesis in rat embryos in vivo and in vitro.
Topics: Animals; Congenital Abnormalities; Diabetes Mellitus, Experimental; Dietary Supplements; Female; Folic Acid; Glucose; Neural Tube Defects; Pregnancy; Pregnancy in Diabetics; Rats; RNA; Tail | 2005 |
A diabetes-like environment increases malformation rate and diminishes prostaglandin E(2) in rat embryos: reversal by administration of vitamin E and folic acid.
Topics: Animals; Congenital Abnormalities; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dinoprostone; Embryo Culture Techniques; Embryo, Mammalian; F2-Isoprostanes; Female; Folic Acid; Male; Pregnancy; Pregnancy in Diabetics; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Vitamin E | 2005 |
Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine-Homocysteine S-Methyltransferase; Blood Glucose; Diabetes Mellitus, Experimental; Diet; Folic Acid; Glycine N-Methyltransferase; Homocysteine; Liver; Male; Nutritional Status; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Weight Gain | 2006 |
Folic acid supplementation affects ROS scavenging enzymes, enhances Vegf-A, and diminishes apoptotic state in yolk sacs of embryos of diabetic rats.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Catalase; Diabetes Mellitus, Experimental; Female; Folic Acid; Gene Expression Regulation, Developmental; Gestational Age; Glutathione Peroxidase; Glycine N-Methyltransferase; Oxidoreductases; Pregnancy; Pregnancy in Diabetics; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Vascular Endothelial Growth Factor A; Yolk Sac | 2007 |
Micronuclei in diabetes: folate supplementation diminishes micronuclei in diabetic patients but not in an animal model.
Topics: Adult; Animals; Animals, Newborn; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dietary Supplements; Female; Folic Acid; Humans; Male; Micronucleus Tests; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Wistar | 2007 |
Effects of folic acid on cardiac myocyte apoptosis in rats with streptozotocin-induced diabetes mellitus.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Relationship, Drug; fas Receptor; Folic Acid; Insulin; Male; Malondialdehyde; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Superoxide Dismutase | 2008 |
The administration of folic acid reduces intravascular oxidative stress in diabetic rabbits.
Topics: Alloxan; Animals; Aorta; Body Weight; Diabetes Mellitus, Experimental; Dinoprost; Epoprostenol; Folic Acid; Homocysteine; Male; NADPH Oxidases; Oxidative Stress; Rabbits; Superoxides | 2008 |
Deranged folic acid metabolism in diabetes-induced rats.
Topics: Animals; Diabetes Mellitus, Experimental; Folic Acid; Male; Rats; Rats, Wistar | 1994 |
[Experimental studies on the effects of various vitamins on blood sugar in rats and the mechanism of action].
Topics: Animals; Ascorbic Acid; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Female; Flavonoids; Folic Acid; Hydroxocobalamin; Islets of Langerhans; Male; Niacinamide; Organ Size; ortho-Aminobenzoates; Pyridoxine; Rats; Thiamine; Vitamin B 12 | 1966 |