Page last updated: 2024-08-17

folic acid and Adverse Drug Event

folic acid has been researched along with Adverse Drug Event in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19909 (24.32)18.7374
1990's1 (2.70)18.2507
2000's7 (18.92)29.6817
2010's14 (37.84)24.3611
2020's6 (16.22)2.80

Authors

AuthorsStudies
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
He, H; Hou, A; Luo, M; Ran, S; Song, D; Tang, J; Tang, Y; Wang, H; Wang, T; Yan, X; Yang, R; Yu, B; Zhang, S1
Baumrin, E; Berna, R; Margolis, DJ; Mitra, N; Rosenbach, M1
Arabshahi, HJ; Cait, A; Gasser, O; O'Sullivan, D; Tang, JS; White, RM1
Ashforth, G; Ouellette, S; Razi, S; Shah, R; Wassef, C1
Awad, L; Hashim, R; Jain, M; Labadie, JG; Raheel, S1
Mitsuboshi, S1
Benedicto, A; Márquez, J; Sanz, E1
Bakker, SJL; de Borst, MH; Eggersdorfer, M; Janse, A; Navis, G; Péter, S; van Orten-Luiten, ACB; von Schacky, C; Weber, P; Witkamp, RF; Zhernakova, A1
Fardet, L; Mazaud, C1
Afework, M; Diro, E; Fantaye, W; Taye, M; Worku, A1
Barclay, M; Chapman, PT; Drake, J; Frampton, C; OʼDonnell, JL; Stamp, LK; Zhang, M1
Baye, K1
Cherrington, NJ; Coen, M; Goedken, MJ; Hardwick, RN; Holmes, E; Jin, Z; Kyriakides, M1
Bernardes, M; Canhão, H; Fonseca, JE; Lima, A; Romão, VC1
Chen, Y; Shen, Z1
Kujovich, JL1
Jazbec, J; Karas-Kuzelicki, N; Mlinaric-Rascan, I; Smid, A1
Spence, JD1
Jindal, G; Parmar, VR1
Frankenburg, FR1
Isaacs, A; Obermann-Borst, SA; Steegers, EA; Steegers-Theunissen, RP; van der Heiden, IP; van Duyn, CM; van Schaik, RH; Younes, Z1
Cabrera, RM; Etheredge, AJ; Finnell, RH; Hill, DS1
Casanueva, E; Loría, A; Mares-Galindo, M; Meza-Camacho, C; Schnaas, L; Valdés-Ramos, R; Viteri, FE1
Roe, DA2
Freedman, ML1
Berg, MJ; Lewis, DP; Stumbo, PJ; Van Dyke, DC1
Allen, RH; Lindenbaum, J; Ogundipe, A; Savage, DG; Stabler, SP1
Brundage, SC1
Fricke, NL; Springer, NS1
Fireman, BH; Friedman, GD; Selby, JV1
Basu, TK1
Hoffbrand, AV; Lavoie, A1
Herbert, V; Scott, J; Stebbins, R1
Mayer, J1

Reviews

15 review(s) available for folic acid and Adverse Drug Event

ArticleYear
Methotrexate Cutaneous Ulceration: A Systematic Review of Cases.
    American journal of clinical dermatology, 2022, Volume: 23, Issue:4

    Topics: Drug Eruptions; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Kidney Diseases; Male; Methotrexate; Middle Aged; Pancytopenia; Skin Neoplasms; Skin Ulcer

2022
Fatal low-dose methotrexate toxicity: A case report and literature review.
    Dermatologic therapy, 2022, Volume: 35, Issue:12

    Topics: Aged; Arthritis, Psoriatic; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Male; Methotrexate; Psoriasis; Risk Factors

2022
A 2018 Approach to Combating Methotrexate Toxicity Folic Acid and Beyond.
    Bulletin of the Hospital for Joint Disease (2013), 2018, Volume: 76, Issue:3

    Topics: Antirheumatic Agents; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Methotrexate; Rheumatic Fever; Vitamin B Complex

2018
Ocoxin as a complement to first line treatments in cancer.
    International journal of medical sciences, 2021, Volume: 18, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Chemoradiotherapy; Clinical Trials as Topic; Drug Resistance, Neoplasm; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Neoplasms; Pantothenic Acid; Plant Extracts; Radiation Injuries; Radiation Tolerance; Treatment Outcome; Vitamin B 12; Vitamin B 6; Zinc Sulfate

2021
Maximising benefits and minimising adverse effects of micronutrient interventions in low- and middle-income countries.
    The Proceedings of the Nutrition Society, 2019, Volume: 78, Issue:4

    Topics: Deficiency Diseases; Developing Countries; Dietary Supplements; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Food, Fortified; Humans; Iodine; Iron; Micronutrients; Poverty; Sodium, Dietary

2019
Three decades of low-dose methotrexate in rheumatoid arthritis: can we predict toxicity?
    Immunologic research, 2014, Volume: 60, Issue:2-3

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Carrier Proteins; Dietary Supplements; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Methotrexate; Pharmacogenetics; Prognosis; Signal Transduction

2014
Gene polymorphisms in the folate metabolism and their association with MTX-related adverse events in the treatment of ALL.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:7

    Topics: Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Liver-Specific Organic Anion Transporter 1; Metabolic Networks and Pathways; Methotrexate; Organic Anion Transporters; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase

2015
Evaluation of Anemia.
    Obstetrics and gynecology clinics of North America, 2016, Volume: 43, Issue:2

    Topics: Alcohol Drinking; Anemia, Iron-Deficiency; Anemia, Macrocytic; Blood Cell Count; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Liver Diseases; Myeloproliferative Disorders; Predictive Value of Tests; Primary Health Care; United States; Vitamin B 12; Vitamin B 12 Deficiency; Women's Health

2016
Polypill: for Pollyanna.
    International journal of stroke : official journal of the International Stroke Society, 2008, Volume: 3, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Sodium Chloride Symporter Inhibitors; Stroke

2008
Investigations into the etiology of neural tube defects.
    Birth defects research. Part C, Embryo today : reviews, 2004, Volume: 72, Issue:4

    Topics: Central Nervous System; Diabetes Complications; Drug-Related Side Effects and Adverse Reactions; Female; Fever; Folic Acid; Fumonisins; Humans; Neural Tube Defects; Obesity; Pregnancy; Risk Factors; Teratogens; Vitamin B 12

2004
Drug and environmental factors associated with adverse pregnancy outcomes. Part II: Improvement with folic acid.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:9

    Topics: Animals; Dietary Supplements; Drug-Related Side Effects and Adverse Reactions; Environmental Pollutants; Female; Folic Acid; Humans; MEDLINE; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Randomized Controlled Trials as Topic

1998
Nutrition and drug therapy for persons with developmental disabilities.
    American journal of mental deficiency, 1975, Volume: 80, Issue:3

    Topics: Anticonvulsants; Antidepressive Agents; Appetite; Dextroamphetamine; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Growth; Humans; Hyperkinesis; Intellectual Disability; Metabolism, Inborn Errors; Methylphenidate; Nutritional Physiological Phenomena; Pyridoxine; Tranquilizing Agents; Vitamin B 12; Vitamin D; Vitamins

1975
Drug-vitamin interaction.
    International journal for vitamin and nutrition research. Supplement = Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Supplement, 1985, Volume: 27

    Topics: Anticonvulsants; Ascorbic Acid; Ascorbic Acid Deficiency; Aspirin; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Folic Acid Deficiency; Humans; Nutritional Requirements; Risk; Vitamins

1985
Drug-induced megaloblastic anemias.
    Seminars in hematology, 1973, Volume: 10, Issue:3

    Topics: Anemia, Macrocytic; Anticonvulsants; Contraceptives, Oral; DNA; Drug-Related Side Effects and Adverse Reactions; Erythrocytes; Ethanol; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Humans; Nucleotidyltransferases; Purines; Pyrimidines; Vitamin B 12; Vitamin B 12 Deficiency

1973
Effects of drugs on nutrition.
    Life sciences, 1974, Oct-01, Volume: 15, Issue:7

    Topics: Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Intestinal Absorption; Nutrition Disorders; Nutritional Physiological Phenomena; Nutritional Requirements; Vitamin D

1974

Trials

3 trial(s) available for folic acid and Adverse Drug Event

ArticleYear
Effects of individualized administration of folic acid on prothrombotic state and vascular endothelial function with H-type hypertension: A double-blinded, randomized clinical cohort study.
    Medicine, 2022, Jan-21, Volume: 101, Issue:3

    Topics: Amlodipine; Cohort Studies; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Precision Medicine; Vascular Endothelial Growth Factor A

2022
A Pilot Randomized Controlled Double-Blind Trial of High- Versus Low-Dose Weekly Folic Acid in People With Rheumatoid Arthritis Receiving Methotrexate.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2019, Volume: 25, Issue:7

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Humans; Male; Methotrexate; Middle Aged; Patient Acuity; Pilot Projects; Treatment Outcome; Vitamin B Complex

2019
Weekly iron as a safe alternative to daily supplementation for nonanemic pregnant women.
    Archives of medical research, 2006, Volume: 37, Issue:5

    Topics: Adult; Anemia; Dietary Supplements; Drug-Related Side Effects and Adverse Reactions; Female; Ferritins; Folic Acid; Gestational Age; Hematinics; Hemoglobins; Humans; Infant, Low Birth Weight; Infant, Newborn; Iron; Pregnancy; Pregnancy Complications, Hematologic; Premature Birth; Risk Factors; Vitamin B 12; Vitamin B Complex

2006

Other Studies

19 other study(ies) available for folic acid and Adverse Drug Event

ArticleYear
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
MR1-dependence of unmetabolized folic acid side-effects.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Drug-Related Side Effects and Adverse Reactions; Flour; Folic Acid; Food, Fortified; Histocompatibility Antigens Class I; Humans; Minor Histocompatibility Antigens; Neural Tube Defects

2022
Risk of haematological events and preventive effect of folic acid in methotrexate users with chronic kidney disease and rheumatoid arthritis: Analysis of the Japanese Adverse Drug Event Report database.
    British journal of clinical pharmacology, 2021, Volume: 87, Issue:5

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Japan; Methotrexate; Renal Insufficiency, Chronic

2021
Public health relevance of drug-nutrition interactions.
    European journal of nutrition, 2017, Volume: 56, Issue:Suppl 2

    Topics: Contraceptives, Oral; Drug-Related Side Effects and Adverse Reactions; Fatty Acids, Omega-3; Female; Folic Acid; Food-Drug Interactions; Gastrointestinal Microbiome; Humans; Male; Meta-Analysis as Topic; Micronutrients; Netherlands; Nutritional Status; Public Health; Vitamin D; Vitamin K

2017
Folate Supplementation During Methotrexate Therapy: A Population-based Retrospective Cohort Study.
    Acta dermato-venereologica, 2018, Apr-27, Volume: 98, Issue:5

    Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Child; Child, Preschool; Databases, Factual; Dermatologic Agents; Dietary Supplements; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Guideline Adherence; Humans; Infant; Infant, Newborn; Male; Methotrexate; Middle Aged; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; Risk Factors; Treatment Outcome; Vitamin B Complex; Young Adult

2018
Factors associated with congenital anomalies in Addis Ababa and the Amhara Region, Ethiopia: a case-control study.
    BMC pediatrics, 2018, 04-25, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Alcohol Drinking; Case-Control Studies; Congenital Abnormalities; Contraception Behavior; Dietary Supplements; Drug-Related Side Effects and Adverse Reactions; Environmental Exposure; Ethiopia; Female; Folic Acid; Humans; Infant; Infant, Newborn; Male; Middle Aged; Prenatal Care; Reproductive History; Risk Factors; Socioeconomic Factors; Young Adult

2018
Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 142, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Energy Metabolism; Folic Acid; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methotrexate; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats, Sprague-Dawley; Tissue Distribution

2014
PACSIN2 polymorphism is associated with thiopurine-induced hematological toxicity in children with acute lymphoblastic leukaemia undergoing maintenance therapy.
    Scientific reports, 2016, 07-25, Volume: 6

    Topics: Adaptor Proteins, Signal Transducing; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Mercaptopurine; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrophosphatases

2016
Is it safe to dispense loose iron folic acid tablets?
    Indian journal of pediatrics, 2009, Volume: 76, Issue:4

    Topics: Anemia, Iron-Deficiency; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Humans; Infant; Iron; Tablets

2009
Folate supplementation: is it safe and effective?
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:5

    Topics: Adolescent; Child; Cross-Sectional Studies; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Humans; Interviews as Topic; Prevalence; Stress Disorders, Post-Traumatic; Surveys and Questionnaires

2009
General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect.
    American journal of obstetrics and gynecology, 2011, Volume: 204, Issue:3

    Topics: Adult; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Genetic Predisposition to Disease; Heart Defects, Congenital; Humans; Infant; Maternal Exposure; Polymorphism, Genetic; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Surveys and Questionnaires; Vitamin B Complex

2011
Intergroup and intragroup variables affecting interpretation of studies of drug effects on nutritional status.
    Progress in clinical and biological research, 1981, Volume: 77

    Topics: Absorption; Animals; Contraceptives, Oral; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Energy Intake; Erythrocytes; Female; Folic Acid; Food; Humans; Milk; Nutritional Physiological Phenomena; Nutritional Requirements; Riboflavin

1981
Anemias in the elderly: physiologic or pathologic?
    Hospital practice (Hospital ed.), 1982, Volume: 17, Issue:5

    Topics: Aged; Aging; Alcoholism; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Pernicious; Animals; Blood Cell Count; Drug-Related Side Effects and Adverse Reactions; Female; Ferrous Compounds; Folic Acid; Folic Acid Deficiency; Gastrointestinal Hemorrhage; Humans; Male; Mice; Reference Values; Vitamin B 12

1982
Etiology and diagnostic evaluation of macrocytosis.
    The American journal of the medical sciences, 2000, Volume: 319, Issue:6

    Topics: Adult; Aged; Alcohol Drinking; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; L-Lactate Dehydrogenase; Leukocyte Count; Liver Diseases; Liver Diseases, Alcoholic; Male; Methylmalonic Acid; Middle Aged; Platelet Count; Predictive Value of Tests; Prospective Studies; Reticulocyte Count; Sensitivity and Specificity; Vitamin B 12; Vitamin B 12 Deficiency

2000
Preconception health care.
    American family physician, 2002, Jun-15, Volume: 65, Issue:12

    Topics: Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Environmental Exposure; Female; Folic Acid; Health Behavior; Humans; Neural Tube Defects; Preconception Care; Pregnancy; Pregnancy Complications; Prenatal Care

2002
Screening prescription drugs for possible carcinogenicity: eleven to fifteen years of follow-up.
    Cancer research, 1989, Oct-15, Volume: 49, Issue:20

    Topics: Anti-Bacterial Agents; Atropa belladonna; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Erythromycin; Esophageal Neoplasms; Folic Acid; Follow-Up Studies; Gastrointestinal Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neomycin; Neoplasms; Phenylbutazone; Piperidones; Plants, Medicinal; Plants, Toxic; Polymyxin B; Propantheline; Secobarbital; Sulfathiazoles; Vitamins

1989
Blood and neoplastic diseases: megaloblastic anaemia.
    British medical journal, 1974, Jun-08, Volume: 2, Issue:5918

    Topics: Anemia, Macrocytic; Anemia, Pernicious; Blood Cell Count; Diet, Vegetarian; Drug-Related Side Effects and Adverse Reactions; Folic Acid; Folic Acid Deficiency; Humans; Hydroxocobalamin; Intestinal Diseases; Potassium; Vitamin B 12; Vitamin B 12 Deficiency

1974
Iatrogenic malnutrition.
    Postgraduate medicine, 1971, Volume: 49, Issue:3

    Topics: Adolescent; Anemia, Macrocytic; Anticonvulsants; Antitubercular Agents; Calcium; Celiac Disease; Child; Contraceptives, Oral; Drug-Related Side Effects and Adverse Reactions; Female; Folic Acid; Folic Acid Deficiency; Humans; Iatrogenic Disease; Male; Middle Aged; Neomycin; Nutrition Disorders; Osteomalacia; Pyridoxine; Rickets; Vitamin B 12

1971