Page last updated: 2024-08-17

folic acid and Adenoma

folic acid has been researched along with Adenoma in 110 studies

Research

Studies (110)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (1.82)	18.7374
1990's	12 (10.91)	18.2507
2000's	70 (63.64)	29.6817
2010's	25 (22.73)	24.3611
2020's	1 (0.91)	2.80

Authors

Authors	Studies
Barták, BK; Felletár, I; Galamb, O; Igaz, P; Kalmár, A; Márkus, E; Micsik, T; Molnár, B; Nagy, ZB; Papp, M; Szigeti, KA; Takács, I; Tulassay, Z; V Patai, Á; Valcz, G; Zsigrai, S	1
Agarwal, N	1
Baron, JA; Barry, EL; Bresalier, RS; Gangar, P; Karagas, MR; McKeown-Eyssen, G; Passarelli, MN; Rees, JR; Zhang, D	1
Coppedè, F; Lazzarotti, A; Migliore, L; Spisni, R; Stoccoro, A	1
Chen, HM; Chen, XY; Chen, YX; Fang, DC; Fang, JY; Gao, QY; Ge, ZZ; Sheng, JQ; Tang, JT; Wang, YC; Wang, ZH; Yu, CG; Zheng, P	1
Ahnen, DJ; Baron, JA; Barry, EL; Bradshaw, PT; Bresalier, RS; Fedirko, V; Figueiredo, JC; Milne, GL; Sandler, RS	1
Pot, GK; van Dijk, M	1
Barcella, W; Bonetti, M; Cole, BF; Gelber, RD; Lazar, A; Wang, XV; Yip, WK	1
Chen, HM; Ding, H; Fang, JY; Gao, QY	1
Giardina, C; Hanley, MP; Kadaveru, K; Perret, C; Rosenberg, DW	1
Axelrod, BN; Jaszewski, R; Kucuk, O; Levi, E; Majumdar, AP; Misra, S; Naumoff, JA; Patel, BB; Tobi, M; Ullah, N	1
Barrett, JH; Bishop, T; Carey, FA; Forman, D; Key, TJ; Lightfoot, TJ; Northwood, EL; Smith, G; Steele, RJ; Wilkie, MJ; Wolf, R	1
Ahnen, DJ; Ali, I; Baron, JA; Barry, EL; Figueiredo, JC; Grau, MV; Haile, RW; Levine, AJ; Midttun, O; Munroe, D; Sandler, RS; Tsang, S; Ueland, PM	1
Ahnen, D; Ali, IU; Baron, JA; Barry, EL; Cole, BF; Haile, RW; Levine, AJ; Munroe, DJ; Saibil, F; Tsang, S; Ueland, P; Wallace, K	1
Evans, CO; Laborde, D; Oyesiku, NM; Yao, C	1
Ahnen, DJ; Baron, JA; Barry, EL; Bond, J; Bresalier, RS; Byers, T; Figueiredo, JC; Grau, MV; Haile, RW; Levine, AJ; McKeown-Eyssen, GE; Sandler, RS; Summers, RW; Ueland, PM	1
Choi, SW; Mason, JB; Sauer, J	1
Iwasaki, M; Sakamoto, H; Sasazuki, S; Tsugane, S; Yamaji, T; Yoshida, T	1
Deng, L; Lawrance, AK; Rozen, R	1
Al-Ghnaniem, R; Ally, MS; Pufulete, M	1
Baron, JA; Bresalier, RS; Burke, CA; Figueiredo, JC; Grau, MV; Haile, RW; McKeown-Eyssen, GE; Sandler, RS; Summers, RW	1
Giovannucci, E; Lee, IM; Lee, JE; Li, H; Ma, J; Selhub, J; Stampfer, M	1
Baron, JA; Bresalier, RS; Chen, X; Figueiredo, JC; Grau, MV; Haile, RW; Hamdan, R; Issa, JP; Levine, AJ; McKeown-Eyssen, G; Shen, L; Wallace, K	1
Evans, CO; Owens, TR; Oyesiku, NM; Stevens, VL; Yao, C	1
Ahnen, DJ; Ali, IU; Baron, JA; Barry, EL; Bresalier, RS; Burke, C; Grau, MV; Gui, J; McKeown-Eyssen, GE; Munroe, DJ; Saibil, F; Sandler, RS; Sansbury, LB; Tsang, S	1
Ahnen, DJ; Baron, JA; Barry, EL; Bresalier, RS; Cushman, M; Ho, GY; McKeown-Eyssen, G; Rohan, TE; Saibil, F; Sandler, RS; Xue, X	1
Fife, J; Frizelle, FA; Hider, PN; Raniga, S	1
Fuchs, CS; Giovannucci, E; Hunter, DJ; Platz, EA; Rosner, BA; Selhub, J; Willett, WC; Wu, K	1
Baron, JA; Chao, WH; Hazra, A; Hunter, DJ; Selhub, J; Ueland, PM	1
Booth, A; Carroll, C; Cooper, K; Hind, D; Papaioannou, D; Pilgrim, H; Tappenden, P	1
Baron, JA; Grau, MV; Levine, AJ; Mott, LA; Ueland, PM	1
Ahnen, D; Baron, JA; Barry, EL; Chen, X; Grau, MV; Gui, J; Haile, RW; Hamdan, R; Issa, JP; Levine, AJ; McKeown-Eyssen, G; Shen, L; Wallace, K	1
Baron, JA; Cole, B; Figueiredo, JC; Giovannucci, E; Grainge, MJ; Logan, RF; Mott, LA; Wu, K	1
Fuchs, CS; Giovannucci, E; Lee, JE; Ma, J; Smith-Warner, SA; Willett, WC; Wu, K	1
Conti, DV; Davis, BD; Edlund, CK; Figueiredo, JC; Haile, RW; Heber, D; Henning, SM; Lee, W; Levine, AJ; Stern, MC; Vandenberg, DJ	1
Fujimori, S; Gudis, K; Kotoyori, M; Ohaki, Y; Sakamoto, C; Takahashi, Y; Tatsuguchi, A	1
Arulkumaran, S; Talaulikar, VS	1
Berndt, SI; Burdette, LA; Han, SS; Rosenberg, PS; Selhub, J; Sue, LY; Ziegler, RG	1
Ziegler, RG	1
Cook, NR; Giovannucci, E; Lee, IM; Manson, JE; Paul, L; Selhub, J; Song, Y; Zhang, SM	1
Blom, HJ; Botma, A; Jung, AY; Kampman, E; Kvalheim, G; Lute, C; Midttun, Ø; Nagengast, F; Steegenga, W; Ueland, PM	1
Bogazzi, F; Lombardi, M; Marciano, E; Martino, E; Pellegrini, G; Ruocco, L; Sardella, C; Scattina, I; Signori, S; Urbani, C	1
Al-Ghnaniem Abbadi, R; Emery, P; Pufulete, M	1
Eguchi, H; Kiyohara, C; Kono, S; Marugame, T; Oda, T; Shinchi, K; Tsuji, E	1
Al-Ghnaniem, R; Appleby, P; Emery, PW; Gout, S; Leather, AJ; Pufulete, M; Sanders, TA; Terry, C	1
Choi, M; Hwang, SW; Kim, YI; Kotsopoulos, J; Martin, R; McKerlie, C; Medline, A; Renlund, R; Sohn, KJ	1
Dhar, R; Ehrinpreis, M; Finkenauer, R; Jaszewski, R; Kucuk, O; Majumdar, AP; Moragoda, L; Nagothu, KK; Naumoff, JA; Rishi, AK; Tobi, M	1
Emery, PW; Pufulete, M; Sanders, TA	1
Bailey, LB	1
Bigler, J; Goode, EL; Potter, JD; Ulrich, CM	1
Benamouzig, R; Chaussade, S	1
Axelrod, BN; Finkenauer, R; Hatfield, JS; Jaszewski, R; Kucuk, O; Majumdar, AP; Millar, B; Naumoff, JA; Nogothu, K; Rishi, AK	1
Alberts, DS; Henning, SM; Martínez, ME	1
Brandenburg, S; Cruz-Correa, M; Cui, H; Feinberg, AP; Giardiello, FM; He, X; Hutcheon, DF; Hylind, L; Kafonek, DR; Powe, NR; Robinson, A; Wu, Y	1
Fuchs, C; Giovannucci, E; Hankinson, SE; Hunter, DJ; Ma, J; Tranah, GJ	1
Bostick, RM; Boyapati, SM; Coker, A; Fina, MF; Geisinger, KR; Hebert, JR; McGlynn, KA; Roufail, WM; Wargovich, M	1
Braam, H; Diergaarde, B; Kampman, E; Kok, FJ; Nagengast, FM; Tiemersma, EW; van Muijen, GN	1
Kroesen, A; Pox, C; Schmiegel, W	1
Gill, S; Sinicrope, FA	1
Al-Ghnaniem, R; Appleby, P; Emery, PW; Gout, S; Harris, N; Khushal, A; Pufulete, M; Sanders, TA	1
Hahn, A; Ströhle, A; Wolters, M	1
Buijsse, B; Harryvan, JL; Kampman, E; Kok, FJ; Nagengast, FM; Ocké, MC; van den Berg, SW; van den Donk, M	1
Chen, K; Kono, S	1
Bruce, WR; Cirocco, M; Giacca, A; Kim, YI; Marcon, N; Minkin, S	1
Bigler, J; Caan, B; Curtin, K; Potter, JD; Slattery, ML; Ulrich, CM	1
Alberts, DS; Giovannucci, E; Henning, SM; Jacobs, ET; Jiang, R; Martínez, ME; Smith-Warner, SA; Thompson, P	1
Brody, LC; Deng, L; Finnell, RH; Lawrance, AK; Rozen, R; Shane, B	1
Armitage, N; Chau, I; Grainge, M; Houlston, RS; Hubner, RA; Liu, JF; Logan, RF; Muir, KR; Sellick, GS	1
Ahnen, DJ; Baron, JA; Barry, EL; Bhat, S; Burke, CA; Grau, MV; Haile, RW; O'Brien, TG; Sandler, RS	1
Alberts, DS; Giovannucci, E; Jacobs, ET; Jiang, R; Klimecki, W; Martínez, ME; Thompson, P	1
Harryvan, JL; Kampman, E; Kok, FJ; van den Donk, M; Visker, MH	1
Kampman, E; Keijer, J; Kok, FJ; Pellis, L; van den Donk, M; van Engeland, M; Witteman, BJ	1
Akhgar, A; Ashktorab, H; Begum, R; Daremipouran, M; Elbedawi, M; Giardiello, FM; Momen, B; Smoot, DT; Zhao, A	1
Fuchs, CS; Giovannucci, EL; Hazra, A; Hunter, DJ; Kraft, P; Wu, K	1
Ahnen, DJ; Allen, JI; Baron, JA; Barry, EL; Beck, GJ; Bond, JH; Bresalier, RS; Burke, CA; Byers, T; Church, TR; Cole, BF; Greenberg, ER; Haile, RW; Mandel, JS; Marcon, N; McKeown-Eyssen, G; Mott, LA; Pearson, LH; Rees, JR; Robertson, DJ; Rothstein, RI; Saibil, F; Sandler, RS; Snover, DC; Summers, RW; Ueland, PM	1
Potter, JD; Ulrich, CM	1
Antal, M; Arató, G; Bereczky, M; Lugasi, A; Pallai, Z; Regöly-Mérei, A; Telek, G	1
Peek, R; Reddy, KR	1
Chae, YK; Yun, JH	1
Al-Ghnaniem, R; Foresti, R; Heaton, N; Peters, J; Pufulete, M	1
Houlston, RS; Hubner, RA; Liu, JF; Logan, RF; Muir, KR; Sellick, GS	1
Armitage, NC; Grainge, MJ; Logan, RF; Muir, KR; Shepherd, VC	1
Bayston, R; Hoffbrand, AV; Russell, A; Wald, NJ	1
Albert, PS; Cross, AJ; Kalidindi, A; Laiyemo, A; Lanza, E; Lehman, T; Modali, R; Murphy, G; Sansbury, LB; Schatzkin, A; Stolzenberg-Solomon, R; Wang, Z	1
Lundberg, GD	1
Grainge, MJ; Houlston, RS; Hubner, RA; Liu, JF; Logan, RF; Muir, KR	1
Brower, V	1
Ascherio, A; Colditz, GA; Giovannucci, E; Rimm, EB; Stampfer, MJ; Willett, WC	1
Kalafatis, E; Karamanolis, DG; Koutsioumpa, P; Oros, L; Paspatis, GA; Xourgias, V	1
Chaves, P; Cravo, M; Fidalgo, P; Gouveia-Oliveira, A; Leitao, CN; Mason, JB; Mira, FC; Pereira, AD; Selhub, J	1
Colditz, GA; Giovannucci, E; Rimm, EB; Rosner, BA; Speizer, FE; Stampfer, MJ; Trichopoulos, D; Willett, WC	1
Belghiti, C; Boutron-Ruault, MC; Couillault, C; Faivre, J; Senesse, P	1
Kupper, LL; Murray, SC; Sandler, RS; Tseng, M	1
Baron, JA; Greenberg, ER; Haile, RW; Mandel, JS; Mott, LA; Sandler, RS	1
Arora, S; Fawaz, K; Kim, YI; Knox, T; Lee, YM; Mason, JB; Norton, R; Paiva, L	1
Chen, J; Giovannucci, E; Hankinson, SE; Hunter, DJ; Kelsey, KT; Ma, J; Spiegelman, D; Willett, WC	1
Chen, J; Giovannucci, EL; Hunter, DJ	1
Ahnen, DJ; Alberts, DS; Einspahr, J; Hamilton, SR; Maltzman, T; Marshall, JR; Martínez, ME; Reid, ME; Sampliner, R	1
Brown, SE; Gelroth, JA; Glaser, BK; Ranhotra, GS; Schoening, P	1
Ash, C; Gallinger, S; Kim, YI; Medline, A; Sohn, KJ; Song, J	1
Gallinger, S; Kim, YI; Mason, JB; Medline, A; Song, J	1
Le Leu, RK; McIntosh, GH; Young, GP	1
Fawaz, K; Kim, YI; Knox, T; Lee, YM; Libby, E; Mason, JB; Norton, R	1
Freedman, AN; Ishibe, N	1
Ryan, BM; Weir, DG	1
Fan, K; Kopelovich, L; Lipkin, M; Liu, Y; Newmark, HL; Shinozaki, H; Yang, K	1
Hawk, ET; Umar, A; Viner, JL	1
Bigler, J; Bostick, R; Fosdick, L; Potter, JD; Ulrich, CM	1
Panizon, F; Ventura, A	1
Hyde, RD; McBrien, MP	1

Reviews

15 review(s) available for folic acid and Adenoma

Article	Year
The effects of nutritional interventions on recurrence in survivors of colorectal adenomas and cancer: a systematic review of randomised controlled trials. European journal of clinical nutrition, 2016, Volume: 70, Issue:5 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Antioxidants; Cancer Survivors; Colorectal Neoplasms; Dietary Supplements; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nutrition Therapy; Randomized Controlled Trials as Topic; Time; Treatment Outcome	2016
Too much folate: a risk factor for cancer and cardiovascular disease? Current opinion in clinical nutrition and metabolic care, 2009, Volume: 12, Issue:1 Topics: Adenoma; Cardiovascular Diseases; Chronic Disease; Colorectal Neoplasms; Dietary Supplements; Dose-Response Relationship, Drug; Epigenesis, Genetic; Folic Acid; Homocysteine; Humans; Neoplasms; Risk Factors	2009
Folic acid supplementation and colorectal cancer risk: a meta-analysis. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2011, Volume: 13, Issue:2 Topics: Adenoma; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Time Factors	2011
Meta-analysis: folic acid in the chemoprevention of colorectal adenomas and colorectal cancer. Alimentary pharmacology & therapeutics, 2010, Volume: 31, Issue:7 Topics: Adenoma; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Folic Acid; Humans; Randomized Controlled Trials as Topic	2010
Folic acid in obstetric practice: a review. Obstetrical & gynecological survey, 2011, Volume: 66, Issue:4 Topics: Adenoma; Animals; Colorectal Neoplasms; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Humans; Neural Tube Defects; Pregnancy; Prenatal Care	2011
Folate, DNA methylation and colo-rectal cancer. The Proceedings of the Nutrition Society, 2003, Volume: 62, Issue:2 Topics: Adenoma; Animals; Anticarcinogenic Agents; Colorectal Neoplasms; DNA Methylation; Dose-Response Relationship, Drug; Folic Acid; Humans; Polymorphism, Genetic; Risk Factors	2003
Folate, methyl-related nutrients, alcohol, and the MTHFR 677C-->T polymorphism affect cancer risk: intake recommendations. The Journal of nutrition, 2003, Volume: 133, Issue:11 Suppl 1 Topics: Adenoma; Alcohol Drinking; Colonic Neoplasms; Folic Acid; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutation, Missense; Neoplasms; Nutrition Policy; Polymorphism, Single Nucleotide; Risk Factors; Vitamin B 12	2003
Colorectal cancer prevention: is an ounce of prevention worth a pound of cure? Seminars in oncology, 2005, Volume: 32, Issue:1 Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Calcium; Clinical Trials as Topic; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Eflornithine; Folic Acid; Humans; Intestinal Mucosa; Selenium; Ursodeoxycholic Acid	2005
Folic acid and colorectal cancer prevention: molecular mechanisms and epidemiological evidence (Review). International journal of oncology, 2005, Volume: 26, Issue:6 Topics: Adenoma; Colorectal Neoplasms; DNA Methylation; ErbB Receptors; Folic Acid; Humans	2005
Genetic polymorphisms of methylenetetrahydrofolate reductase and colorectal cancer and adenoma. Cancer science, 2005, Volume: 96, Issue:9 Topics: Adenoma; Colorectal Neoplasms; Epidemiologic Studies; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; Polymorphism, Genetic	2005
MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis. The Journal of nutrition, 1999, Volume: 129, Issue:2S Suppl Topics: Adenoma; Carcinoma; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors	1999
Understanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis. Cancer investigation, 2001, Volume: 19, Issue:5 Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p27; Dietary Fiber; Environmental Exposure; Enzyme Inhibitors; Folic Acid; Genes, APC; Genes, bcl-2; Genes, DCC; Genes, p53; Genes, ras; Genes, Tumor Suppressor; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Microtubule-Associated Proteins; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Smoking; Tumor Suppressor Proteins	2001
Relevance of folate metabolism in the pathogenesis of colorectal cancer. The Journal of laboratory and clinical medicine, 2001, Volume: 138, Issue:3 Topics: Adenoma; Animals; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; DNA, Neoplasm; Folic Acid; Folic Acid Deficiency; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Vitamin B 12	2001
The future of colon cancer prevention. Annals of the New York Academy of Sciences, 2001, Volume: 952 Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Biomarkers; Calcium; Clinical Trials as Topic; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diagnostic Imaging; Disease Progression; Drug Design; Drug Synergism; Eflornithine; Enzyme Inhibitors; ErbB Receptors; Folic Acid; Forecasting; Genes, APC; Humans; Isoenzymes; Membrane Proteins; Mice; Models, Biological; Oligonucleotide Array Sequence Analysis; Ornithine Decarboxylase Inhibitors; Prostaglandin-Endoperoxide Synthases; Proteome; Risk	2001
[Juvenile endocrine hypoglycemia]. Minerva medica, 1979, Jun-16, Volume: 70, Issue:28 Topics: Adenoma; Child, Preschool; Diazoxide; Folic Acid; Fructose-1,6-Diphosphatase Deficiency; Gluconeogenesis; Growth Hormone; Humans; Hyperinsulinism; Hyperplasia; Hypoglycemia; Islets of Langerhans; Ketosis; Pancreatic Neoplasms; Prognosis	1979

Trials

24 trial(s) available for folic acid and Adenoma

Article	Year
Risk of basal cell carcinoma in a randomized clinical trial of aspirin and folic acid for the prevention of colorectal adenomas. The British journal of dermatology, 2018, Volume: 179, Issue:2 Topics: Adenoma; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carcinoma, Basal Cell; Colorectal Neoplasms; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Risk Assessment; Skin; Skin Neoplasms; Treatment Outcome	2018
Folic acid prevents the initial occurrence of sporadic colorectal adenoma in Chinese older than 50 years of age: a randomized clinical trial. Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:7 Topics: Adenoma; Case-Control Studies; Colonoscopy; Colorectal Neoplasms; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Prospective Studies; Risk Factors; Vitamin B Complex	2013
Urinary metabolites of prostanoids and risk of recurrent colorectal adenomas in the Aspirin/Folate Polyp Prevention Study (AFPPS). Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:11 Topics: Adenoma; Administration, Oral; Aged; Aspirin; Chromatography, Gas; Chromatography, Liquid; Colonoscopy; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Humans; Male; Mass Spectrometry; Middle Aged; Neoplasm Recurrence, Local; Poisson Distribution; Prostaglandins	2015
Folic acid supplementation inhibits recurrence of colorectal adenomas: a randomized chemoprevention trial. World journal of gastroenterology, 2008, Jul-28, Volume: 14, Issue:28 Topics: Adenoma; Aged; Colonoscopy; Colorectal Neoplasms; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Longitudinal Studies; Male; Middle Aged; Neoplasm Recurrence, Local; Risk Factors; Treatment Outcome	2008
Vitamins B2, B6, and B12 and risk of new colorectal adenomas in a randomized trial of aspirin use and folic acid supplementation. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:8 Topics: Adenoma; Alcohol Drinking; Aspirin; Chemoprevention; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Genotype; Humans; Incidence; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Poisson Distribution; Polymorphism, Genetic; Riboflavin; Risk; Surveys and Questionnaires; Vitamin B 12; Vitamin B 6	2008
MTHFR genotype and colorectal adenoma recurrence: data from a double-blind placebo-controlled clinical trial. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:9 Topics: Adenoma; Alleles; Aspirin; Chi-Square Distribution; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Genotype; Humans; Linear Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Placebos; Polymorphism, Genetic	2008
Colorectal adenomas in a randomized folate trial: the role of baseline dietary and circulating folate levels. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:10 Topics: Adenoma; Aspirin; Colonoscopy; Colorectal Neoplasms; Confidence Intervals; Diet; Female; Folic Acid; Humans; Incidence; Linear Models; Male; Middle Aged; Placebos; Poisson Distribution; Risk Factors; Surveys and Questionnaires	2008
Folic acid and risk of prostate cancer: results from a randomized clinical trial. Journal of the National Cancer Institute, 2009, Mar-18, Volume: 101, Issue:6 Topics: Adenoma; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Dietary Supplements; Double-Blind Method; Folic Acid; Follow-Up Studies; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Prostatic Neoplasms; Research Design; Surveys and Questionnaires; United States; Vitamin B Complex	2009
Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:4 Topics: Adenoma; Alcohol Drinking; Aspirin; Colon; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; CpG Islands; Diet; Dietary Supplements; DNA Methylation; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Life Style; Long Interspersed Nucleotide Elements; Male; Middle Aged; Phenotype; Prospective Studies; Risk Factors; Smoking; Vitamin B 6	2009
Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trial. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:10 Topics: Adenoma; Aged; Aspirin; Cohort Studies; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Folic Acid; Gene Frequency; Genetic Variation; Genotype; Haplotypes; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk Assessment	2009
A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma. The American journal of clinical nutrition, 2009, Volume: 90, Issue:6 Topics: Adenoma; Aged; Colorectal Neoplasms; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies	2009
Baseline plasma total homocysteine and adenoma recurrence: results from a double blind randomized clinical trial of aspirin and folate supplementation. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:10 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aspirin; Colorectal Neoplasms; Double-Blind Method; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Surveys and Questionnaires; Young Adult	2010
Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:12 Topics: Adenoma; Biomarkers, Tumor; Colon; Colonic Polyps; Colorectal Neoplasms; CpG Islands; DNA Methylation; Double-Blind Method; Estrogen Receptor alpha; Female; Folic Acid; Follow-Up Studies; Humans; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Male; Membrane Proteins; Middle Aged; Placebos; Prognosis; Rectum	2010
Associations between genes in the one-carbon metabolism pathway and advanced colorectal adenoma risk in individuals with low folate intake. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012, Volume: 21, Issue:3 Topics: Adenoma; Aged; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Gene Expression Profiling; Genotype; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; One-Carbon Group Transferases; Polymorphism, Single Nucleotide; Prognosis; Risk Factors	2012
Effect of combined folic acid, vitamin B(6), and vitamin B(12) on colorectal adenoma. Journal of the National Cancer Institute, 2012, Oct-17, Volume: 104, Issue:20 Topics: Adenoma; Adult; Aged; Anticarcinogenic Agents; Cardiovascular Diseases; Colorectal Neoplasms; Double-Blind Method; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Linear Models; Male; Middle Aged; Poisson Distribution; Risk Assessment; Risk Factors; Vitamin B 12; Vitamin B 6	2012
Short-term folate supplementation in physiological doses has no effect on ESR1 and MLH1 methylation in colonic mucosa of individuals with adenoma. Journal of nutrigenetics and nutrigenomics, 2012, Volume: 5, Issue:6 Topics: Adaptor Proteins, Signal Transducing; Adenoma; Aged; Colon; Colorectal Neoplasms; DNA Methylation; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Estrogen Receptor alpha; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Male; Middle Aged; MutL Protein Homolog 1; Nuclear Proteins; Placebos; Time Factors	2012
Folic acid mediated attenuation of loss of heterozygosity of DCC tumor suppressor gene in the colonic mucosa of patients with colorectal adenomas. Cancer detection and prevention, 2003, Volume: 27, Issue:4 Topics: Adenoma; Adenomatous Polyposis Coli Protein; Administration, Oral; Aged; Cell Adhesion Molecules; Cell Division; Colorectal Neoplasms; DCC Receptor; DNA, Neoplasm; Double-Blind Method; Female; Folic Acid; Genes, p53; Hematinics; Humans; Intestinal Mucosa; Loss of Heterozygosity; Male; Middle Aged; Placebos; Receptors, Cell Surface; Tumor Suppressor Proteins	2003
Folic acid reduces nuclear translocation of beta-catenin in rectal mucosal crypts of patients with colorectal adenomas. Cancer letters, 2004, Mar-31, Volume: 206, Issue:1 Topics: Adenoma; Adolescent; Adult; beta Catenin; Cell Nucleus; Colorectal Neoplasms; Cytoskeletal Proteins; Dietary Supplements; ErbB Receptors; Female; Folic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Intestinal Mucosa; Male; Middle Aged; Phosphorylation; Pilot Projects; Placebos; Trans-Activators	2004
Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma. Gut, 2005, Volume: 54, Issue:5 Topics: Adenoma; Aged; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; DNA, Neoplasm; Double-Blind Method; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Leukocytes; Male; Middle Aged; Rectum	2005
A pilot randomised controlled trial to reduce colorectal cancer risk markers associated with B-vitamin deficiency, insulin resistance and colonic inflammation. British journal of cancer, 2005, Sep-19, Volume: 93, Issue:6 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; C-Reactive Protein; Calcium Carbonate; Colitis; Colorectal Neoplasms; Dietary Supplements; Female; Fish Oils; Folic Acid; Humans; Insulin Resistance; Male; Middle Aged; Pilot Projects; Risk Factors; Thiamine; Treatment Outcome; Vitamin B 12 Deficiency; Vitamin B Deficiency	2005
Folate fortification, plasma folate, homocysteine and colorectal adenoma recurrence. International journal of cancer, 2006, Sep-15, Volume: 119, Issue:6 Topics: Adenoma; Aged; Colorectal Neoplasms; Diet; Dietary Fiber; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Food, Fortified; Homocysteine; Humans; Male; Neoplasm Recurrence, Local; Risk Factors; Ursodeoxycholic Acid; Vitamin B Complex	2006
Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA, 2007, Jun-06, Volume: 297, Issue:21 Topics: Adenoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chi-Square Distribution; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Neoplasms; Risk; Treatment Failure	2007
Aspirin and folic acid for the prevention of recurrent colorectal adenomas. Gastroenterology, 2008, Volume: 134, Issue:1 Topics: Adenoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemotherapy, Adjuvant; Colonoscopy; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Hematinics; Humans; Male; Middle Aged; Neoplasm Recurrence, Local	2008
DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1994, Volume: 3, Issue:6 Topics: Adenoma; Adult; Aged; Biomarkers, Tumor; Carcinoma; Colorectal Neoplasms; DNA; Female; Folic Acid; Humans; In Vitro Techniques; Intestinal Mucosa; Male; Methylation; Middle Aged; Prospective Studies	1994

Other Studies

71 other study(ies) available for folic acid and Adenoma

Article	Year
Global DNA hypomethylation of colorectal tumours detected in tissue and liquid biopsies may be related to decreased methyl-donor content. BMC cancer, 2022, Jun-02, Volume: 22, Issue:1 Topics: Adenoma; Colorectal Neoplasms; DNA; DNA Methylation; Folate Receptor 2; Folic Acid; Humans; Inflammatory Bowel Diseases; Liquid Biopsy; RNA, Messenger; S-Adenosylmethionine	2022
Letter to the Editor. Utility of folate receptor-targeted fluorescent dye for resection of pituitary adenomas. Journal of neurosurgery, 2018, Volume: 129, Issue:2 Topics: Adenoma; Endoscopy; Fluorescent Dyes; Folic Acid; Humans; Pituitary Neoplasms	2018
Investigation of GHSR and GHRL methylation in colorectal cancer. Epigenomics, 2018, Volume: 10, Issue:12 Topics: Adenoma; Aged; Aged, 80 and over; Biomarkers, Tumor; Colorectal Neoplasms; DNA Methylation; Epigenomics; Female; Folic Acid; Ghrelin; Humans; Male; Middle Aged; MutL Protein Homolog 1; Neoplasm Staging; Polymorphism, Genetic; Receptors, Ghrelin; ROC Curve	2018
Subpopulation Treatment Effect Pattern Plot (STEPP) analysis for continuous, binary, and count outcomes. Clinical trials (London, England), 2016, Volume: 13, Issue:4 Topics: Adenoma; Aspirin; Biomarkers, Tumor; Colorectal Neoplasms; Data Interpretation, Statistical; Folic Acid; Humans; Models, Statistical; Randomized Controlled Trials as Topic; Risk; Survival Analysis; Treatment Outcome	2016
People with low serum folate levels have higher risk of colorectal adenoma/advanced colorectal adenoma occurrence and recurrence in China. The Journal of international medical research, 2016, Volume: 44, Issue:4 Topics: Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; China; Colorectal Neoplasms; Female; Folic Acid; Humans; Logistic Models; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Risk Factors; Young Adult	2016
Dietary Methyl Donor Depletion Suppresses Intestinal Adenoma Development. Cancer prevention research (Philadelphia, Pa.), 2016, Volume: 9, Issue:10 Topics: Adenoma; Animals; Choline; Diet; Folic Acid; Intestinal Neoplasms; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Random Allocation; Vitamin B 12	2016
Methylene tetrahydrofolate reductase genotype modifies the chemopreventive effect of folate in colorectal adenoma, but not colorectal cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:9 Topics: Adenoma; Aged; Aged, 80 and over; Alcohol Drinking; Case-Control Studies; Chi-Square Distribution; Colorectal Neoplasms; England; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Risk Factors; Scotland; Surveys and Questionnaires	2008
Folate receptor expression in pituitary adenomas cellular and molecular analysis. Vitamins and hormones, 2008, Volume: 79 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Animals; Cell Line; Cell Proliferation; Female; Folate Receptor 1; Folic Acid; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Middle Aged; Mutation; Pituitary Neoplasms; Protein Binding; Receptor, Notch3; Receptors, Cell Surface; Receptors, Notch; RNA, Messenger	2008
Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenoma; Adult; Aged; Alcohol Drinking; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genotype; Humans; Logistic Models; Male; Middle Aged; Polymorphism, Genetic; Risk; Surveys and Questionnaires	2009
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice. Gut, 2009, Volume: 58, Issue:6 Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Colorectal Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Pregnancy; Prenatal Nutritional Physiological Phenomena; Random Allocation; Thymine Nucleotides; Uridine Triphosphate; Weaning	2009
The relationship between gene-specific DNA methylation in leukocytes and normal colorectal mucosa in subjects with and without colorectal tumors. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:3 Topics: Adenoma; Aged; Analysis of Variance; Biomarkers; Case-Control Studies; Chi-Square Distribution; Colonic Polyps; Colorectal Neoplasms; CpG Islands; DNA Methylation; Estrogen Receptor alpha; Female; Folic Acid; Humans; Intestinal Mucosa; Leukocytes; Male; Middle Aged; Polymerase Chain Reaction; Statistics, Nonparametric	2009
Prospective study of plasma vitamin B6 and risk of colorectal cancer in men. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:4 Topics: Adenoma; Adult; Aged; Aged, 80 and over; C-Reactive Protein; Case-Control Studies; Colorectal Neoplasms; Folic Acid; Humans; Incidence; Interleukin-6; Male; Middle Aged; Physicians; Prospective Studies; Pyridoxal Phosphate; Randomized Controlled Trials as Topic; Tumor Necrosis Factor-alpha; Vitamin B 12; Vitamin B 6	2009
Folate receptor alpha regulates cell proliferation in mouse gonadotroph alphaT3-1 cells. Experimental cell research, 2009, Nov-01, Volume: 315, Issue:18 Topics: Adenoma; Animals; Carrier Proteins; Cell Line; Cell Proliferation; Disease Models, Animal; Folate Receptors, GPI-Anchored; Folic Acid; Gonadotrophs; Humans; Mice; Pituitary Neoplasms; Proliferating Cell Nuclear Antigen; Receptor, Notch3; Receptors, Cell Surface; Receptors, Notch; Transfection; Up-Regulation	2009
Antagonistic effects of aspirin and folic acid on inflammation markers and subsequent risk of recurrent colorectal adenomas. Journal of the National Cancer Institute, 2009, Dec-02, Volume: 101, Issue:23 Topics: Adenoma; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; C-Reactive Protein; Colorectal Neoplasms; Drug Administration Schedule; Drug Antagonism; Female; Folic Acid; Humans; Inflammation; Interleukin-6; Male; Middle Aged; Risk Assessment; Risk Factors; Tumor Necrosis Factor-alpha	2009
Uracil misincorporation into DNA and folic acid supplementation. The American journal of clinical nutrition, 2010, Volume: 91, Issue:1 Topics: Adenoma; Aged; Alcohol Drinking; Aspirin; Colonoscopy; Colorectal Neoplasms; Dietary Supplements; DNA; Female; Folic Acid; Humans; Intestinal Mucosa; Male; Middle Aged; Neoplasm Recurrence, Local; Placebos; Randomized Controlled Trials as Topic; Risk Factors; Uracil	2010
Folic acid and prevention of colorectal adenomas: a combined analysis of randomized clinical trials. International journal of cancer, 2011, Jul-01, Volume: 129, Issue:1 Topics: Adenoma; Aged; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic	2011
Folate intake and risk of colorectal cancer and adenoma: modification by time. The American journal of clinical nutrition, 2011, Volume: 93, Issue:4 Topics: Adenoma; Adult; Aged; Colorectal Neoplasms; Diet Surveys; Female; Folic Acid; Humans; Male; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; Time; Vitamin B Complex	2011
Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study. Cancer causes & control : CCC, 2011, Volume: 22, Issue:4 Topics: Adenoma; Aged; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Models, Biological; Polymorphism, Single Nucleotide; Reduced Folate Carrier Protein; Risk Factors; Sigmoidoscopy	2011
Determination of the minimal essential serum folate concentration for reduced risk of colorectal adenoma. Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:5 Topics: Adenoma; Adult; Aged; Colorectal Neoplasms; Cross-Sectional Studies; Female; Folic Acid; Folic Acid Deficiency; Hospitals, Teaching; Humans; Japan; Male; Mass Screening; Middle Aged; Prevalence; Prospective Studies; Risk; Sex Factors; Vitamin B 12; Vitamin B 12 Deficiency	2011
Following up folate and its function in colorectal carcinogenesis. Journal of the National Cancer Institute, 2012, Oct-17, Volume: 104, Issue:20 Topics: Adenoma; Anticarcinogenic Agents; Cardiovascular Diseases; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Vitamin B 12; Vitamin B 6	2012
Plasma B vitamins and LINE-1 DNA methylation in leukocytes of patients with a history of colorectal adenomas. Molecular nutrition & food research, 2013, Volume: 57, Issue:4 Topics: Adenoma; Adolescent; Adult; Aged; Colorectal Neoplasms; Cross-Sectional Studies; DNA Methylation; Female; Folic Acid; Follow-Up Studies; Genotype; Humans; Leukocytes; Life Style; Linear Models; Long Interspersed Nucleotide Elements; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multivariate Analysis; Risk Factors; Surveys and Questionnaires; Vitamin B Complex; Young Adult	2013
Serum factors associated with precancerous colonic lesions in acromegaly. Journal of endocrinological investigation, 2013, Volume: 36, Issue:8 Topics: Acromegaly; Adenoma; Adult; Aged; Calcifediol; Cohort Studies; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Fasting; Female; Folic Acid; Homocysteine; Humans; Insulin; Male; Middle Aged; Precancerous Conditions; Somatostatin	2013
Relation of plasma folate and methylenetetrahydrofolate reductase C677T polymorphism to colorectal adenomas. International journal of epidemiology, 2003, Volume: 32, Issue:1 Topics: Adenoma; Case-Control Studies; Colorectal Neoplasms; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk	2003
Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study. Gastroenterology, 2003, Volume: 124, Issue:5 Topics: Adenoma; Aged; Case-Control Studies; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Risk Factors	2003
Dietary folate deficiency suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats. Carcinogenesis, 2003, Volume: 24, Issue:5 Topics: Adenocarcinoma; Adenoma; Alkylating Agents; Animals; Body Weight; Diet; DNA Methylation; DNA, Neoplasm; Female; Folic Acid; Folic Acid Deficiency; Incidence; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley	2003
Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenoma; Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Genotype; Humans; Logistic Models; Male; Middle Aged; Minnesota; Polymorphism, Genetic; Risk Factors; Sex Distribution	2004
[Chemopreventive agents in colorectal cancer]. La Revue du praticien, 2003, Dec-31, Volume: 53, Issue:20 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Colorectal Neoplasms; Controlled Clinical Trials as Topic; Cyclooxygenase Inhibitors; Female; Folic Acid; Follow-Up Studies; Hematinics; Humans; Middle Aged; Multicenter Studies as Topic; Placebos; Prospective Studies; Risk; Risk Factors; Time Factors	2003
Folate and colorectal neoplasia: relation between plasma and dietary markers of folate and adenoma recurrence. The American journal of clinical nutrition, 2004, Volume: 79, Issue:4 Topics: Adenoma; Adult; Aged; Colorectal Neoplasms; Diet; Female; Folic Acid; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Neoplasm Recurrence, Local; Risk Factors; Surveys and Questionnaires	2004
Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. Gastroenterology, 2004, Volume: 126, Issue:4 Topics: Adenoma; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Calcium; Colonic Neoplasms; Cross-Sectional Studies; Dietary Fats; Dietary Fiber; Environmental Exposure; Female; Folic Acid; Genomic Imprinting; Humans; Insulin-Like Growth Factor II; Male; Middle Aged; Multivariate Analysis; Risk Factors; Selenium; Smoking	2004
XRCC2 and XRCC3 polymorphisms are not associated with risk of colorectal adenoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:6 Topics: Adenoma; Alcohol Drinking; Case-Control Studies; Colorectal Neoplasms; DNA-Binding Proteins; Folic Acid; Genotype; Humans; Logistic Models; Nurses; Polymorphism, Genetic; Risk Factors; Smoking	2004
Folate intake, MTHFR C677T polymorphism, alcohol consumption, and risk for sporadic colorectal adenoma (United States). Cancer causes & control : CCC, 2004, Volume: 15, Issue:5 Topics: Adenoma; Adult; Aged; Alcohol Drinking; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Humans; Incidence; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors	2004
Dietary factors and truncating APC mutations in sporadic colorectal adenomas. International journal of cancer, 2005, Jan-01, Volume: 113, Issue:1 Topics: Adenoma; Adult; Aged; Alcohol Drinking; Animals; Ascorbic Acid; beta Carotene; Calcium, Dietary; Case-Control Studies; Colorectal Neoplasms; Dairy Products; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; DNA, Neoplasm; Edible Grain; Energy Intake; Feeding Behavior; Female; Fishes; Folic Acid; Fruit; Genes, APC; Humans; Male; Meat; Middle Aged; Mutation; Netherlands; Poultry; Sequence Analysis, DNA; Vegetables	2005
[Ulcerative colitis. Cancer prevention]. Zeitschrift fur Gastroenterologie, 2004, Volume: 42, Issue:9 Topics: Adenoma; Adenomatous Polyposis Coli; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Case-Control Studies; Child; Cholagogues and Choleretics; Cholangitis, Sclerosing; Colectomy; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Cross-Sectional Studies; Female; Folic Acid; Follow-Up Studies; Humans; Male; Meta-Analysis as Topic; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Ursodeoxycholic Acid	2004
Dietary intake of folate and riboflavin, MTHFR C677T genotype, and colorectal adenoma risk: a Dutch case-control study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:6 Topics: Adenoma; Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Netherlands; Polymorphism, Genetic; Riboflavin	2005
Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:11 Pt 1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenoma; Adult; Aged; Case-Control Studies; Colonic Neoplasms; Diet; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Male; Membrane Transport Proteins; Middle Aged; Odds Ratio; Polymorphism, Genetic; Reduced Folate Carrier Protein; Thymidylate Synthase	2005
Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. The Journal of nutritional biochemistry, 2007, Volume: 18, Issue:5 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenoma; Adenomatous Polyposis Coli Protein; Animals; Apoptosis; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Intestinal Neoplasms; Male; Membrane Transport Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; Reduced Folate Carrier Protein	2007
Folate metabolism polymorphisms influence risk of colorectal adenoma recurrence. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:9 Topics: Adenoma; Adult; Aged; Colorectal Neoplasms; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Polymorphism, Genetic; Risk	2006
Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention. Journal of the National Cancer Institute, 2006, Oct-18, Volume: 98, Issue:20 Topics: Adenoma; Adenomatous Polyposis Coli; Aged; Alanine; Anticarcinogenic Agents; Aspirin; Colorectal Neoplasms; Female; Folic Acid; Gastrointestinal Agents; Gene Frequency; Genotype; Glycine; Humans; Male; Middle Aged; Ornithine Decarboxylase; Polymorphism, Single Nucleotide; Racial Groups; Randomized Controlled Trials as Topic; Risk Assessment	2006
Dietary factors and biomarkers involved in the methylenetetrahydrofolate reductase genotype-colorectal adenoma pathway. Gastroenterology, 2006, Volume: 131, Issue:6 Topics: Adenoma; Aged; Biomarkers, Tumor; Carbon; Colorectal Neoplasms; Dietary Supplements; DNA Methylation; Female; Folic Acid; Genotype; Homeostasis; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Polymorphism, Genetic; Prospective Studies; Risk Factors; Vitamins	2006
Dietary intake of B-vitamins, polymorphisms in thymidylate synthase and serine hydroxymethyltransferase 1, and colorectal adenoma risk: a Dutch case-control study. Cancer letters, 2007, May-18, Volume: 250, Issue:1 Topics: Adenoma; Aged; Case-Control Studies; Colorectal Neoplasms; Diet; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Middle Aged; Netherlands; Polymorphism, Genetic; Riboflavin; Risk Factors; Thymidylate Synthase; Vitamin B 12; Vitamin B 6; Vitamin B Complex	2007
Dietary folate intake in combination with MTHFR C677T genotype and promoter methylation of tumor suppressor and DNA repair genes in sporadic colorectal adenomas. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:2 Topics: Adenoma; Adolescent; Adult; Aged; Case-Control Studies; Colorectal Neoplasms; DNA Methylation; DNA Repair; Female; Folic Acid; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Genotype; Humans; Logistic Models; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Netherlands; Polymerase Chain Reaction; Promoter Regions, Genetic; Surveys and Questionnaires	2007
Folate status and risk of colorectal polyps in African Americans. Digestive diseases and sciences, 2007, Volume: 52, Issue:6 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Black or African American; Case-Control Studies; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Genes, APC; Homocysteine; Humans; Male; Middle Aged; Promoter Regions, Genetic; Smoking; Tetrahydrofolates; Vitamin B 12; Vitamins	2007
Twenty-four non-synonymous polymorphisms in the one-carbon metabolic pathway and risk of colorectal adenoma in the Nurses' Health Study. Carcinogenesis, 2007, Volume: 28, Issue:7 Topics: Adenoma; Adult; Alcohol Drinking; Betaine-Homocysteine S-Methyltransferase; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Ferredoxin-NADP Reductase; Folic Acid; Genetics, Population; Humans; Methionine; Middle Aged; One-Carbon Group Transferases; Polymorphism, Single Nucleotide; Prospective Studies; Risk; Transcobalamins; Vitamin B 12	2007
Folate and cancer--timing is everything. JAMA, 2007, Jun-06, Volume: 297, Issue:21 Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Folic Acid; Humans; Neoplasms; Risk; Treatment Failure	2007
[Nutritional and antioxidant status of colorectal cancer patients]. Orvosi hetilap, 2007, Aug-12, Volume: 148, Issue:32 Topics: Adenoma; Aged; Antioxidants; Biomarkers; Carcinoma; Case-Control Studies; Colorectal Neoplasms; Dietary Fiber; Female; Folic Acid; Free Radical Scavengers; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Middle Aged; Nutritional Status; Obesity; Overweight; Prealbumin; Vitamin A	2007
Folic Acid supplements do not appear to reduce risk of colorectal tumors. Gastroenterology, 2007, Volume: 133, Issue:2 Topics: Adenoma; Anticarcinogenic Agents; Colorectal Neoplasms; Dietary Supplements; Folic Acid; Humans; Risk Assessment; Risk Factors; Vitamin B Complex	2007
Folic acid and prevention of colorectal adenomas. JAMA, 2007, Sep-26, Volume: 298, Issue:12 Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Folic Acid; Humans; Risk; Vitamin B Complex	2007
Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia. The American journal of clinical nutrition, 2007, Volume: 86, Issue:4 Topics: Adaptor Proteins, Signal Transducing; Adenoma; Aged; Base Sequence; Biomarkers; Case-Control Studies; Colon; Colonic Polyps; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Estrogen Receptor alpha; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; MutL Protein Homolog 1; Nuclear Proteins; Nutritional Status; Vitamin B 12	2007
Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenoma. British journal of cancer, 2007, Nov-19, Volume: 97, Issue:10 Topics: Adenoma; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Folic Acid; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Surveys and Questionnaires; Thymidylate Synthase; Vitamin B Complex	2007
Folic acid fortification and cancer risk. Lancet (London, England), 2007, Dec-15, Volume: 370, Issue:9604 Topics: Adenoma; Canada; Colorectal Neoplasms; Folic Acid; Food, Fortified; Humans; Incidence; Neural Tube Defects; Risk Factors; United States	2007
Folate and MTHFR: risk of adenoma recurrence in the Polyp Prevention Trial. Cancer causes & control : CCC, 2008, Volume: 19, Issue:7 Topics: Adenoma; Aged; Alleles; Colorectal Neoplasms; Female; Folic Acid; Follow-Up Studies; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Recurrence, Local; Odds Ratio; Surveys and Questionnaires; Vitamin B Complex	2008
Aspirin helps prevent recurring colorectal adenomas--folic acid does not. Medscape journal of medicine, 2008, Mar-20, Volume: 10, Issue:3 Topics: Adenoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemotherapy, Adjuvant; Colonoscopy; Colorectal Neoplasms; Double-Blind Method; Female; Folic Acid; Hematinics; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Randomized Controlled Trials as Topic	2008
Dairy products, polymorphisms in the vitamin D receptor gene and colorectal adenoma recurrence. International journal of cancer, 2008, Aug-01, Volume: 123, Issue:3 Topics: Adenoma; Adult; Aged; Animals; Aspirin; Calcium Compounds; Colorectal Neoplasms; Dairy Products; Female; Folic Acid; Humans; Male; Middle Aged; Milk; Neoplasm Recurrence, Local; Polymorphism, Genetic; Randomized Controlled Trials as Topic; Receptors, Calcitriol; Risk Assessment; Risk Factors; Surveys and Questionnaires; Transcription Factors; United Kingdom; Vitamin D	2008
An apple a day may be safer than vitamins. Journal of the National Cancer Institute, 2008, Jun-04, Volume: 100, Issue:11 Topics: Adenoma; Animals; Antioxidants; Colonic Neoplasms; Colonic Polyps; Dietary Supplements; Drug Synergism; Feeding Behavior; Folic Acid; Fruit; Humans; Malus; Neoplasms; Safety; Vegetables; Vitamins	2008
Alcohol, low-methionine--low-folate diets, and risk of colon cancer in men. Journal of the National Cancer Institute, 1995, Feb-15, Volume: 87, Issue:4 Topics: Adenoma; Adult; Aged; Alcohol Drinking; Carcinoma; Colonic Neoplasms; Diet; Folic Acid; Humans; Male; Methionine; Middle Aged; Risk Factors; Surveys and Questionnaires	1995
Folate status and adenomatous colonic polyps. A colonoscopically controlled study. Diseases of the colon and rectum, 1995, Volume: 38, Issue:1 Topics: Adenoma; Aged; Colonic Polyps; Colonoscopy; Female; Folic Acid; Hematocrit; Humans; Male; Middle Aged	1995
Folate, methionine, and alcohol intake and risk of colorectal adenoma. Journal of the National Cancer Institute, 1993, Jun-02, Volume: 85, Issue:11 Topics: Adenoma; Adult; Aged; Alcohol Drinking; Colorectal Neoplasms; Feeding Behavior; Female; Folic Acid; Humans; Male; Methionine; Methylation; Middle Aged; Prevalence; Prospective Studies; Proto-Oncogene Mas; Risk; Surveys and Questionnaires	1993
Folate and alcohol intakes: related or independent roles in the adenoma-carcinoma sequence? Nutrition and cancer, 1996, Volume: 26, Issue:3 Topics: Adenoma; Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Drug Interactions; Ethanol; Female; Folic Acid; Humans; Male; Middle Aged; Odds Ratio; Risk Factors	1996
Micronutrients and the risk of colorectal adenomas. American journal of epidemiology, 1996, Dec-01, Volume: 144, Issue:11 Topics: Adenoma; Calcium, Dietary; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Iron; Male; Micronutrients; Middle Aged; Odds Ratio; Risk; Vitamins	1996
Folate intake, alcohol consumption, cigarette smoking, and risk of colorectal adenomas. Journal of the National Cancer Institute, 1998, Jan-07, Volume: 90, Issue:1 Topics: Adenoma; Aged; Alcohol Drinking; Anticarcinogenic Agents; Clinical Trials as Topic; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Multicenter Studies as Topic; Risk; Risk Factors; Smoking	1998
Colonic mucosal concentrations of folate correlate well with blood measurements of folate status in persons with colorectal polyps. The American journal of clinical nutrition, 1998, Volume: 68, Issue:4 Topics: Adenoma; Biopsy; Colon; Colonic Polyps; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Hyperplasia; Intestinal Mucosa; Male; Middle Aged; Nutritional Status	1998
A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma. Carcinogenesis, 1998, Volume: 19, Issue:12 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenoma; Adult; Colorectal Neoplasms; Ethanol; Female; Folic Acid; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Prospective Studies; Risk Factors	1998
Risk factors for Ki-ras protooncogene mutation in sporadic colorectal adenomas. Cancer research, 1999, Oct-15, Volume: 59, Issue:20 Topics: Adenoma; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Genes, ras; Humans; Male; Middle Aged; Mutation; Risk Factors	1999
Cellulose and calcium lower the incidence of chemically-induced colon tumors in rats. Plant foods for human nutrition (Dordrecht, Netherlands), 1999, Volume: 54, Issue:4 Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Calcium, Dietary; Carcinogens; Cellulose; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Disease Models, Animal; Folic Acid; Male; Random Allocation; Rats; Rats, Inbred F344	1999
Chemopreventive effects of dietary folate on intestinal polyps in Apc+/-Msh2-/- mice. Cancer research, 2000, Jun-15, Volume: 60, Issue:12 Topics: Adenoma; Adenomatous Polyposis Coli Protein; Age Factors; Animals; Body Weight; Colon; Colorectal Neoplasms; CpG Islands; Cytoskeletal Proteins; Diet; DNA-Binding Proteins; Folic Acid; Intestinal Polyps; Intestine, Small; Methylation; Mice; Mice, Inbred C57BL; Microsatellite Repeats; MutS Homolog 2 Protein; Precancerous Conditions; Proto-Oncogene Proteins	2000
Effects of dietary folate on intestinal tumorigenesis in the apcMin mouse. Cancer research, 2000, Oct-01, Volume: 60, Issue:19 Topics: Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Colonic Neoplasms; Diet; Female; Folic Acid; Genes, APC; Genetic Predisposition to Disease; Intestinal Neoplasms; Intestinal Polyps; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions	2000
Folate deficiency reduces the development of colorectal cancer in rats. Carcinogenesis, 2000, Volume: 21, Issue:12 Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Folic Acid; Folic Acid Deficiency; Intestinal Neoplasms; Male; Rats; Rats, Sprague-Dawley	2000
Colonic mucosal concentrations of folate are accurately predicted by blood measurements of folate status among individuals ingesting physiologic quantities of folate. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:6 Topics: Adenoma; Adult; Colonic Neoplasms; Diet; Dietary Supplements; Female; Folic Acid; Hematinics; Homocysteine; Humans; Intestinal Mucosa; Male; Reproducibility of Results; Sensitivity and Specificity	2001
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice. Carcinogenesis, 2001, Volume: 22, Issue:11 Topics: Adenoma; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Choline; Colonic Neoplasms; Diet; Dietary Fats; Epithelium; Female; Folic Acid; Immunoenzyme Techniques; Intestine, Large; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Vitamin B 12	2001
Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas. Cancer research, 2002, Jun-15, Volume: 62, Issue:12 Topics: Adenoma; Adenomatous Polyps; Adult; Aged; Case-Control Studies; Colonoscopy; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Factors; Thymidylate Synthase	2002
Massive renal adenoma associated with intestinal malabsorption. The British journal of surgery, 1970, Volume: 57, Issue:7 Topics: Adenoma; Adult; Anemia, Macrocytic; Female; Folic Acid; Humans; Kidney Neoplasms; Malabsorption Syndromes; Nephrectomy	1970