folic acid has been researched along with Adenocarcinoma in 123 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (8.94) | 18.7374 |
| 1990's | 23 (18.70) | 18.2507 |
| 2000's | 32 (26.02) | 29.6817 |
| 2010's | 47 (38.21) | 24.3611 |
| 2020's | 10 (8.13) | 2.80 |
| Authors | Studies |
|---|---|
| Abirami, P; Alharthi, SS; Govindarasu, M; Rajakumar, G; Thiruvengadam, M; Vaiyapuri, M | 1 |
| Kim, YJ; Lee, YJ; Park, Y | 1 |
| Azari, F; Chang, A; Delikatny, EJ; Desphande, C; Din, A; Kennedy, G; Kucharczuk, J; Marfatia, I; Nadeem, B; Singhal, S; Sullivan, N | 1 |
| Baudouin, A; Beaurain, M; Couraud, S; Herledan, C; Ranchon, F; Rioufol, C; Souquet, PJ; Teixeira, A; Vantard, N | 1 |
| Azari, F; Bou-Samra, P; Chang, A; Delikatny, E; Din, A; Doraid, J; Galandarova, A; Ibrahimli, A; Karimov, Z; Kennedy, G; Kucharczuk, J; Nadeem, B; Pechet, T; Singhal, S; Zhang, K | 1 |
| Debnath, MC; Ganguly, S; Kazi, J; Mukhopadhyay, R; Paul, B; Sen, R | 1 |
| Imtiyaz, K; Moshahid A Rizvi, M; Nenavathu, BP; Singh, G | 1 |
| Cambria, MT; Condorelli, GG; Federico, C; Laudani, S; Pulvirenti, L; Saccone, S; Sinatra, F; Villaggio, G | 1 |
| Alfar, RA; Broman, MM; Cresswell, GM; Crist, SA; Dimitrov, DS; Elzey, BD; Eruslanov, EB; Kischuk, EM; Kularatne, SA; Low, PS; Ratliff, TL; Singhal, S; Sundaram, CP; Vickman, RE; Wang, B | 1 |
| Yin, Z; Zhang, C; Zhao, Z | 1 |
| Chen, Y; Fan, Z; Hou, Z; Li, Y; Lin, J; Ma, J; Su, G; Xie, L; Zhang, H; Zhang, Y; Zhu, X | 1 |
| Arteta, B; Benedicto, A; Hernandez-Unzueta, I; Herrero, A; Márquez, J; Olaso, E; Romayor, I; Sanz, E | 1 |
| Aguiar Junior, S; Carraro, DM; Ferrari, A; Torrezan, GT | 1 |
| Hu, C; Lei, B; Liu, Y; Nie, G; Qin, J; Rong, J; Xiao, Y; Zheng, M | 1 |
| Allen, TC | 1 |
| Azevedo, E; Kameo, SY; Martins-Filho, PR; Mascarenhas-Oliveira, AC; Vieira, NF | 1 |
| Cho, RC; Cole, PD; Croxford, R; Ishiguro, L; Kamen, BA; Kim, SE; Kim, YI; Ly, A; Sohn, KJ | 1 |
| Carroll, PR; Chan, JM; Davies, BJ; O'Keefe, DS; Richman, EL; Sadetsky, N; Tomaszewski, JJ | 1 |
| Anderson, LA; Cantwell, MM; Carsin, AE; Murray, LJ; Sharp, L | 1 |
| Chandra, S; Kundu, SC; Subia, B; Talukdar, S | 1 |
| Chen, L; Gao, W; Kong, LX; Li, P; Wang, Y; Zeng, F | 1 |
| Croxford, R; Deghan Manshadi, S; Ishiguro, L; Kim, YI; Medline, A; Renlund, R; Sohn, KJ | 1 |
| Helke, KL; Kistner-Griffin, E; Krupenko, NI; Krupenko, SA; Oleinik, NV | 1 |
| Ang, Y; Hau, C; Keld, R; Kumar, N; Sajid, J; Thian, M | 1 |
| Aggarwal, C; Albelda, S; Barbosa, EM; DeJesus, E; Deshpande, C; Jiang, J; Judy, R; Low, PS; Nie, S; Okusanya, OT; Simone, CB; Singhal, S | 1 |
| Hwang, SG; Jang, HG; Jeon, YJ; Kim, JO; Kim, JW; Kim, NK; Kwon, SW; Oh, D; Oh, J; Park, HM | 1 |
| Cho, SH; Jeon, YJ; Kim, JO; Kim, JW; Kim, NK; Ko, JJ; Oh, D; Oh, J; Yoo, JK | 1 |
| Albelda, SM; Deshpande, C; Drebin, JA; Heitjan, DF; Keating, JJ; Kennedy, GT; Litzky, LA; Low, PS; Nie, S; Okusanya, OT; Singhal, S | 1 |
| Liao, W; Liu, Y; Ma, H; Shao, X; Shi, M; Xing, MM; Zhong, W | 1 |
| Amin, MC; Amjad, MW; Butt, AM; Iyer, AK; Katas, H; Kesharwani, P | 1 |
| Abnous, K; Alibolandi, M; Hadizadeh, F; Hosseinkhani, H; Ramezani, M; Sadeghi, F | 1 |
| Björkqvist, HG; Carlsson, GU; Gustavsson, BG; Kurlberg, GK; Odin, EA; Stoffregen, CC; Tångefjord, MT | 1 |
| Liu, S; Ouyang, M; Peng, Y; Qin, Y; Yang, H; Zeng, X; Zhou, C | 1 |
| Costache, M; Galateanu, B; Ginghina, O; Hayes, AW; Hudita, A; Ion, RM; Negrei, C; Nikitovic, D; Spandidos, DA; Stan, M; Tsatsakis, AM | 1 |
| Abnet, CC; Dawsey, SM; Fan, J; Murphy, G; Qiao, Y; Ren, J; Selhub, J; Taylor, PR | 1 |
| Aggarwal, C; Alley, EW; Bagley, SJ; Blair, IA; Cohen, RB; Evans, TL; Langer, CJ; Vachani, A; Vitale, S; Whitehead, AS; Zhang, S | 1 |
| Colvin, H; Doki, Y; Hata, T; Ishii, H; Kawamoto, K; Konno, M; Koseki, J; Miyo, M; Mizushima, T; Mori, M; Nishida, N; Nishimura, J; Takemasa, I; Tsunekuni, K | 1 |
| Cantoral, A; Chen, J; Galván-Portillo, MV; Hernandez-Ramirez, RU; Herrera-Goepfert, R; López-Carrillo, L; Oñate-Ocaña, LF; Palma-Coca, O; Torres-Sanchez, L | 1 |
| Guo, Y; Holley, AC; Huang, F; McCormick, CL; York, AW; Zhang, Y | 1 |
| Arpin, D; Biron, E; Cadranel, J; Duruisseaux, M; Guérin, JC; Pérol, M | 1 |
| Cerny, T; D'Addario, G; Früh, M; Gillessen, S; Omlin, A; von Hessling, A | 1 |
| Ibrahim, EM; Zekri, JM | 1 |
| Fukui, Y; Jin, M; Kawakami, K; Minamoto, T; Oda, M; Oka, T; Takechi, T; Tsukioka, S; Watanabe, G | 1 |
| Church, TR; Dodd, KW; Jiao, L; Meinhold, CL; Oaks, BM; Stolzenberg-Solomon, RZ | 1 |
| Baker, JR; Battista, J; Cao, P; Dunham, T; Kukowska-Latallo, J; Myc, A; Swanson, B | 1 |
| Balbuena, L; Casson, AG | 1 |
| Chaudhary, A; Kanthamneni, N; Prabhu, S; Wang, J | 1 |
| Chen, J; Croxford, R; Kim, YI; Lee, H; Ly, A; Medline, A; Renlund, R; Sie, KK; Sohn, KJ; Thompson, LU | 1 |
| Green, AC; Hayward, N; Hughes, MC; Ibiebele, TI; Montgomery, G; Pandeya, N; Webb, PM; Whiteman, DC; Zhao, Z | 1 |
| de Mejia, EG; Johnson, J | 1 |
| Brand, RE; Greer, JB | 1 |
| Ayrizono, Mde L; Coy, CS; Guimarães, JL; Lima, CS | 1 |
| Jin, XF; Liu, Q; Ran, ZH; Tong, JL; Xiao, SD; Xu, Q; Xu, XT; Yang, CH | 1 |
| Azzoli, CG; Dunne, M; Ginsberg, M; Huntington, M; James, L; Kris, MG; Krug, LM; May, J; Miller, V; Patel, JD; Saunders, M; Sirotnak, FM; Subzwari, S; Tyson, L | 1 |
| Aktas, B; Alkış, N; Coban, S; Ekiz, F; Karabulut, HG; Ormeci, N; Tukun, A; Tuncali, T; Yüksel, O | 1 |
| Asomaning, K; Christiani, DC; Lee, MS; Mark, EJ; Su, L; Wain, JC | 1 |
| Chen, HM; Fang, JY; Hong, J; Lin, YW; Lu, R; Ren, LL; Wang, JL; Zhang, YJ | 1 |
| Khare, S; Verma, M | 1 |
| Edelman, MJ; Pribble, P | 1 |
| Boccia, RV; Bonomi, P; Conley, BA; Edelman, MJ; Garon, EB; Harb, WA; Kraut, MJ; Messmann, RA; Pal, SE; Rogers, JS | 1 |
| Cagle, PT; Low, PS; Murphy, L; Zhai, QJ | 1 |
| Peng, C; Shen, M; Shi, X; Wang, H; Zhang, G; Zheng, L | 1 |
| Bollschweiler, E; Hölscher, AH; Mönig, SP; Nowroth, T; Rosendahl, U; Wolfgarten, E | 1 |
| Choi, M; Hwang, SW; Kim, YI; Kotsopoulos, J; Martin, R; McKerlie, C; Medline, A; Renlund, R; Sohn, KJ | 1 |
| Faessel, HM; Greco, WR; Rustum, YM; Slocum, HK | 2 |
| CONDIT, PT; OWENS, AH; SHNIDER, BI | 1 |
| Bajetta, E; Becerra, C; Buzzoni, R; Celio, L; Ferrari, L; Ilardi, C; John, W; Longarini, R; Marchianò, A; Martinetti, A | 1 |
| Anklesaria, P; Bruckheimer, E; Dutzar, B; Furstoss, K; Harvie, P; Mebel, E; Orthel, J; Paul, R | 1 |
| Ajani, JA; Cohen, DS; Feig, B; Gunderson, LL; Janjan, N; Lynch, PM; Mansfield, PF; Morris, J; Myerson, R; Nivers, R; Pisters, PW | 1 |
| Catane, R; Elkayam, R; Koller, M; Kundel, Y; Pfeffer, MR; Symon, Z; Zehavi, M; Zmora, O | 1 |
| Archer, MC; Hwang, SW; Kim, YI; Kotsopoulos, J; Lu, S; Martin, R; Medline, A; Renlund, R; Sohn, KJ | 1 |
| Abbruzzese, JL; Ahmed, M; Bondy, ML; Chou, TH; Evans, DB; Hassan, MM; Jiao, L; Lenzi, R; Li, D; Li, Y; Pisters, PW; Wolff, RA | 1 |
| Chen, XY; Fei, SJ; Peng, YS; Shi, Y; Xiao, SD | 1 |
| Iani, V; Juzeniene, A; Ma, L; Moan, J; Steindal, AE | 1 |
| Giovannucci, E; Larsson, SC; Wolk, A | 1 |
| Büchler, MW; Hoffmann, K; Jäger, D; Märten, A; Schmidt, J | 1 |
| Bae, KH; Lee, Y; Park, TG | 1 |
| Alonso-Aperte, E; González, MP; Póo-Prieto, R; Varela-Moreiras, G | 1 |
| Hida, T; Hiraki, A; Matsuo, K; Mitsudomi, T; Saito, T; Sato, S; Suzuki, T; Tajima, K; Ueda, R; Yatabe, Y | 1 |
| Caca, K; Feisthammel, J; Mössner, J; Schoppmeyer, K; Schulze, M; Wiedmann, M | 1 |
| Leamon, CP; Nicoson, JS; Parker, N; Reddy, JA; Vetzel, M; Vlahov, IR; Westrick, E | 1 |
| Chayama, K; Hiyama, T; Tanaka, S; Yoshihara, M | 1 |
| Alberts, SR; Ames, M; Goetz, MP; Goldberg, RM; Gornet, MK; Kim, GP; Mahoney, MR; Nicol, SJ; Rubin, J; Weinshilboum, RM | 1 |
| Houghton, JA; Houghton, PJ; Schmidt, C | 1 |
| Bhide, SV; Maru, GB; Sawai, MM | 1 |
| Okabe, H; Takeda, S; Toko, T; Unemi, N; Yuasa, C | 1 |
| Allegra, CJ | 1 |
| Ellis, JA; Jackman, MR; Luzio, JP; Shurety, W | 1 |
| Duch, DS; Dykstra, M; Jansen, M; Knick, VC; Lee, JI; Mullin, RJ; Smith, GK; Stables, J; Topley, P | 1 |
| Bunn, PA; Christensen, K; Edwards, D; Franklin, WA; Kolhouse, JF; Prendegrast, P; Waintrub, M; Woods, J | 1 |
| Dohden, K; Ohmura, K; Watanabe, Y | 1 |
| Alati, T; Bewley, JR; Grindey, GB; Lewis, S; Moran, RG; Shih, C; Worzalla, JF | 1 |
| Fang, JY; Jiang, SJ; Qiu, DK; Xiao, SD; Yuan, JM; Zhu, SS | 1 |
| Meenan, J; O'Hallinan, E; Scott, J; Weir, DG | 1 |
| Patterson, RE; Shannon, JS; White, E | 1 |
| Hansen, SI; Helkjaer, PE; Holm, J; Høier-Madsen, M | 1 |
| Adamek, HE; Riemann, JF | 1 |
| Csiba, A; Hullán, L; Szarvas, T; Szende, B; Trézl, L | 1 |
| Brown, SE; Gelroth, JA; Glaser, BK; Ranhotra, GS; Schoening, P | 1 |
| Little, J | 1 |
| Le Leu, RK; McIntosh, GH; Young, GP | 1 |
| Benson, A; Mulcahy, M | 1 |
| Bisogni, CA; Brinton, LA; Colman, N; Frongillo, EA; Hamman, RF; Levine, RS; Mallin, K; Sauberlich, HE; Stolley, PD; Weinstein, SJ; Ziegler, RG | 1 |
| Duthie, SJ | 1 |
| Hawk, ET; Umar, A; Viner, JL | 1 |
| Krupenko, SA; Oleinik, NV | 1 |
| Dagg, JH; Ferguson, MM; Hutcheon, AW; Mason, DK; Wray, D | 1 |
| Ferone, R; Hynes, JB; Mullin, RJ; Singer, SC; Singh, SK; Waters, KA | 1 |
| Fuhry, MA; Janson, CA; Jordan, SR; Matthews, DA; Nguyen, D; Pino, MJ; Reich, SH; Smith, WW; Webber, S; Welsh, KM | 1 |
| Allegra, CJ; Boarman, D; Chu, E; Zinn, S | 1 |
| Dolnick, BJ; Houghton, JA; Houghton, PJ; Rahman, A; Will, CL | 1 |
| Adkins, DA; Houghton, JA; Houghton, PJ; Rahman, A | 1 |
| Brenes, MM; Brinton, LA; de Britton, RC; Gaitan, E; Herrero, R; Laiming, VA; Potischman, N; Reeves, WC; Tenorio, F | 1 |
| Czajkowski, CA; Matherly, LH; Muench, SP; Psiakis, JT | 1 |
| Carenza, L; Giovagnoli, MR; Prosperi Porta, R; Rulli, G | 1 |
| Houghton, JA; Houghton, PJ | 1 |
| Houghton, JA; Houghton, PJ; Radparvar, S | 2 |
| Cantwell, BM; Harris, AL | 1 |
| Duch, DS; Keith, BR; Mullin, RJ | 1 |
| deGraaf, SS; Houghton, JA; Houghton, PJ; Radparvar, S; Rodman, JR; Wainer, IW; Williams, LG | 1 |
| Hreshchyshyn, MM | 1 |
12 review(s) available for folic acid and Adenocarcinoma
| Article | Year |
|---|---|
Lifestyle interventions can reduce the risk of Barrett's esophagus: a systematic review and meta-analysis of 62 studies involving 250,157 participants.
Topics: Adenocarcinoma; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Aspirin; Barrett Esophagus; Body Mass Index; Confidence Intervals; Diet; Dietary Fiber; Esophageal Neoplasms; Exercise; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Style; Proton Pump Inhibitors; Publication Bias; Risk; Sleep; Smoking | 2021 |
Folic acid supplementation for the prevention of recurrence of colorectal adenomas: metaanalysis of interventional trials.
Topics: Adenocarcinoma; Adenomatous Polyps; Colonic Polyps; Colorectal Neoplasms; Dose-Response Relationship, Drug; Folic Acid; Humans; Intestinal Polyps; Randomized Controlled Trials as Topic; Recurrence; Research Design; Treatment Failure | 2010 |
Dietary factors and pancreatic cancer: the role of food bioactive compounds.
Topics: Adenocarcinoma; Citrus; Curcumin; Diet; Feeding Behavior; Flavonoids; Folic Acid; Food; Humans; Pancreatic Neoplasms; Risk Factors; United States; Vitamin D | 2011 |
New developments in pancreatic cancer.
Topics: Adenocarcinoma; Adiposity; Alcohol Drinking; Blood Group Antigens; Body Mass Index; CA-19-9 Antigen; Diet; Fanconi Anemia Complementation Group N Protein; Folic Acid; Heredity; Humans; Mutation; Nuclear Proteins; Pancreatic Neoplasms; Prognosis; Risk Factors; Smoking; Tumor Suppressor Proteins; Vitamin D | 2011 |
Epigenetics of colon cancer.
Topics: Adenocarcinoma; Colonic Neoplasms; CpG Islands; DNA Methylation; Epigenesis, Genetic; Folic Acid; Histones; Humans; MicroRNAs; Risk Factors | 2012 |
EC145: a novel targeted agent for adenocarcinoma of the lung.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lung Neoplasms; Vinca Alkaloids | 2012 |
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Case-Control Studies; Esophageal Neoplasms; Folic Acid; Gastrointestinal Neoplasms; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Pancreatic Neoplasms; Polymorphism, Genetic; Risk Factors; Stomach Neoplasms | 2006 |
Genetic polymorphisms and esophageal cancer risk.
Topics: Adenocarcinoma; Alcohol Oxidoreductases; Carcinoma, Squamous Cell; Cytochrome P-450 Enzyme System; DNA Repair; Esophageal Neoplasms; Folic Acid; Genes, cdc; Genetic Predisposition to Disease; Humans; Meta-Analysis as Topic; Odds Ratio; Oncogenes; Polymorphism, Genetic; Risk Factors | 2007 |
Chemoprevention of colon cancer.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Biomarkers, Tumor; Calcium; Colonic Neoplasms; Dietary Fats; Dietary Fiber; Female; Folic Acid; Hematinics; Hormones; Humans; Incidence; Male; Models, Theoretical; Vitamin D | 2001 |
The future of colon cancer prevention.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Biomarkers; Calcium; Clinical Trials as Topic; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diagnostic Imaging; Disease Progression; Drug Design; Drug Synergism; Eflornithine; Enzyme Inhibitors; ErbB Receptors; Folic Acid; Forecasting; Genes, APC; Humans; Isoenzymes; Membrane Proteins; Mice; Models, Biological; Oligonucleotide Array Sequence Analysis; Ornithine Decarboxylase Inhibitors; Prostaglandin-Endoperoxide Synthases; Proteome; Risk | 2001 |
Reduced folates and fluoropyrimidine antitumor efficacy.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Folic Acid; Humans; Pyrimidines; Tumor Cells, Cultured | 1989 |
Basic considerations in chemotherapy of gynecologic cancer.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Female; Folic Acid; Genital Neoplasms, Female; Hormones; Humans; Leukopenia; Palliative Care; Purines; Pyrimidines; Radiography; Thrombocytopenia; Uterine Neoplasms | 1968 |
13 trial(s) available for folic acid and Adenocarcinoma
| Article | Year |
|---|---|
The Optical Biopsy: A Novel Technique for Rapid Intraoperative Diagnosis of Primary Pulmonary Adenocarcinomas.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Biopsy; Female; Fluorescein-5-isothiocyanate; Folic Acid; Frozen Sections; Humans; Intraoperative Period; Lung; Lung Neoplasms; Male; Middle Aged; Optical Imaging; Pilot Projects; Predictive Value of Tests; Prospective Studies; Tomography, X-Ray Computed | 2015 |
Reduced folate and serum vitamin metabolites in patients with rectal carcinoma: an open-label feasibility study of pemetrexed with folic acid and vitamin B12 supplementation.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cystathionine; Feasibility Studies; Female; Folic Acid; Folic Acid Antagonists; Homocysteine; Humans; Intestinal Mucosa; Male; Methylmalonic Acid; Middle Aged; Neoadjuvant Therapy; Pemetrexed; Rectal Neoplasms; Rectum; Vitamin B 12 | 2016 |
[Clinical efficacy of vitamin support in lung adenocarcinoma patients treated with pemetrexed second-line chemotherapy].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Disease-Free Survival; Folic Acid; Humans; Lung Neoplasms; Pemetrexed; Treatment Outcome; Vitamin B 12; Vitamin B Complex | 2015 |
Pretreatment Red Blood Cell Total Folate Concentration Is Associated With Response to Pemetrexed in Stage IV Nonsquamous Non-Small-cell Lung Cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pemetrexed; Prognosis; Prospective Studies; Survival Rate; Vitamin B Complex | 2017 |
Folate intake, post-folic acid grain fortification, and pancreatic cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
Topics: Adenocarcinoma; Aged; Cohort Studies; Eating; Female; Folic Acid; Food, Fortified; Humans; Male; Middle Aged; Pancreatic Neoplasms; Proportional Hazards Models; Sex Factors; Surveys and Questionnaires | 2010 |
Pralatrexate with vitamin supplementation in patients with previously treated, advanced non-small cell lung cancer: safety and efficacy in a phase 1 trial.
Topics: Adenocarcinoma; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Tissue Distribution; Vitamin B 12; Vitamin B Complex | 2011 |
Vitamin intake and risk of subtypes of esophageal cancer in Germany.
Topics: Adenocarcinoma; Adult; Alcohol Drinking; Ascorbic Acid; Body Mass Index; Carcinoma, Squamous Cell; Case-Control Studies; Dietary Supplements; Esophageal Neoplasms; Folic Acid; Germany; Humans; Incidence; Male; Pilot Projects; Risk Factors; Smoking; Surveys and Questionnaires; Vitamin A; Vitamin E | 2002 |
Phase II study of pemetrexed disodium (Alimta) administered with oral folic acid in patients with advanced gastric cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Female; Folic Acid; Glutamates; Guanine; Hematinics; Humans; Infusions, Intravenous; Male; Middle Aged; Neutropenia; Pemetrexed; Stomach Neoplasms; Treatment Outcome | 2003 |
Multi-institutional trial of preoperative chemoradiotherapy in patients with potentially resectable gastric carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Folic Acid; Gastrectomy; Humans; Leucovorin; Male; Middle Aged; Neoplasm Staging; Radiotherapy; Stomach Neoplasms; Survival Analysis; Treatment Outcome | 2004 |
A phase I study of oral UFT given concomitantly with standard preoperative radiotherapy for rectal cancer.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Combined Modality Therapy; Female; Folic Acid; Humans; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiotherapy; Rectal Neoplasms; Tegafur; Treatment Outcome; Ultrasonography; Uracil | 2004 |
Impact of interferon-alpha in combined chemoradioimmunotherapy for pancreatic adenocarcinoma (CapRI): first data from the immunomonitoring.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cytokines; Fluorouracil; Folic Acid; Granzymes; Humans; Immunophenotyping; Interferon-alpha; Killer Cells, Natural; Leukocytes; Pancreatic Neoplasms; Prospective Studies | 2007 |
Irinotecan with 5-FU/FA in advanced biliary tract adenocarcinomas: a multicenter phase II trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Biliary Tract Neoplasms; Camptothecin; Female; Fluorouracil; Folic Acid; Humans; Irinotecan; Male; Middle Aged; Survival Analysis; Vitamin B Complex | 2007 |
Pemetrexed and oxaliplatin for metastatic colorectal cancer: results of a phase I Mayo Cancer Center Research Consortium trial, MC0248.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Pemetrexed; Survival Rate; Treatment Outcome; Vitamin B 12 | 2007 |
98 other study(ies) available for folic acid and Adenocarcinoma
| Article | Year |
|---|---|
Synthesis, physicochemical characterization, and in vitro evaluation of biodegradable PLGA nanoparticles entrapped to folic acid for targeted delivery of kaempferitrin.
Topics: Adenocarcinoma; Colonic Neoplasms; Drug Carriers; Folic Acid; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2022 |
Folic Acid and Chitosan-Functionalized Gold Nanorods and Triangular Silver Nanoplates for the Delivery of Anticancer Agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chitosan; Docetaxel; Folic Acid; G2 Phase Cell Cycle Checkpoints; Gold; HeLa Cells; Humans; Metal Nanoparticles; Nanotubes; Paclitaxel; Silver | 2022 |
Presence of non-Newtonian fluid in invasive pulmonary mucinous adenocarcinomas impacts fluorescence during intraoperative molecular imaging of lung cancer.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adenocarcinoma, Mucinous; Contrast Media; Female; Fluorescent Dyes; Folic Acid; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Molecular Imaging; Mucins; Retrospective Studies; Sepharose; Tumor Microenvironment | 2022 |
Intravenous route for folate supplementation in a patient with celiac disease treated by pemetrexed-based chemotherapy for non-small-cell lung cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Celiac Disease; Dietary Supplements; Folic Acid; Humans; Injections, Intravenous; Levoleucovorin; Lung Neoplasms; Pemetrexed | 2023 |
Prospective validation of tumor folate receptor expression density with the association of pafolacianine fluorescence during intraoperative molecular imaging-guided lung cancer resections.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Folic Acid; Humans; Lung Neoplasms; Molecular Imaging; Prospective Studies | 2023 |
Gemcitabine Co-Encapsulated with Curcumin in Folate Decorated PLGA Nanoparticles; a Novel Approach to Treat Breast Adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Curcumin; Deoxycytidine; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Gemcitabine; Humans; Mice, Nude; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer | 2020 |
Fabrication of chlorambucil loaded graphene- oxide nanocarrier and its application for improved antitumor activity.
Topics: Adenocarcinoma; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Chlorambucil; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Liberation; Female; Folic Acid; Gelatin; Graphite; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Kinetics; Nanoparticles; Uterine Cervical Neoplasms | 2020 |
The Interplay between Fe
Topics: Adenocarcinoma; Antineoplastic Agents; Butyric Acid; Cell Line; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Delivery Systems; Ferric Compounds; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Magnetics; Magnetite Nanoparticles; Polyethylene Glycols | 2020 |
Folate Receptor Beta Designates Immunosuppressive Tumor-Associated Myeloid Cells That Can Be Reprogrammed with Folate-Targeted Drugs.
Topics: Adenocarcinoma; Animals; Biomarkers, Tumor; Breast Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Polarity; Cellular Reprogramming Techniques; Cytokines; Folate Receptor 2; Folic Acid; Humans; Immunomodulation; Lung Neoplasms; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myeloid Cells; Myeloid-Derived Suppressor Cells; Tumor Microenvironment; Tumor-Associated Macrophages; Up-Regulation | 2021 |
Integration of phospholipid-hyaluronic acid-methotrexate nanocarrier assembly and amphiphilic drug-drug conjugate for synergistic targeted delivery and combinational tumor therapy.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Drug Carriers; Drug Compounding; Drug Synergism; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Hyaluronic Acid; MCF-7 Cells; Methotrexate; Mice; Mice, Nude; Nanoparticles; Phosphatidylethanolamines; Survival Analysis; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Ocoxin Oral Solution Exerts an Antitumoral Effect in Pancreatic Cancer and Reduces the Stromal-Mediated Chemoresistance.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Ascorbic Acid; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Resistance, Neoplasm; Folic Acid; Gemcitabine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Inbred C57BL; Neoplasms, Experimental; Paclitaxel; Pancreatic Neoplasms; Pantothenic Acid; Plant Extracts; Solutions; Vitamin B 12; Vitamin B 6; Zinc Sulfate | 2019 |
Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer.
Topics: Adenocarcinoma; Carbon Cycle; Colorectal Neoplasms; Diet; Diet Surveys; DNA Methylation; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Staging; Polymorphism, Single Nucleotide; Vitamin B Complex | 2019 |
Fabrication of reduced graphene oxide and sliver nanoparticle hybrids for Raman detection of absorbed folic acid: a potential cancer diagnostic probe.
Topics: Adenocarcinoma; Biosensing Techniques; Coated Materials, Biocompatible; Female; Folic Acid; Graphite; HeLa Cells; Humans; Lung Neoplasms; Metal Nanoparticles; Microscopy, Electron, Transmission; Oxides; Silver; Spectrum Analysis, Raman; Uterine Cervical Neoplasms; Vitamin B Complex | 2013 |
Targeted molecular therapy for lung cancer: exuberance reestablished.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation, Preclinical; Female; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms; Male; Neoplasms | 2013 |
Pemetrexed-induced eyelid edema in lung cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Dexamethasone; Diuretics; Edema; Eyelid Diseases; Female; Folic Acid; Furosemide; Glucocorticoids; Glutamates; Guanine; Humans; Lung Neoplasms; Middle Aged; Pemetrexed; Vitamin B 12 | 2013 |
γ-Glutamyl hydrolase modulation and folate influence chemosensitivity of cancer cells to 5-fluorouracil and methotrexate.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Fluorouracil; Folic Acid; gamma-Glutamyl Hydrolase; HCT116 Cells; Humans; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; RNA, Small Interfering; Transfection; Xenograft Model Antitumor Assays | 2013 |
Impact of folate intake on prostate cancer recurrence following definitive therapy: data from CaPSURE™.
Topics: Adenocarcinoma; Aged; Folic Acid; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Prostatic Neoplasms | 2014 |
Intakes of dietary folate and other B vitamins are associated with risks of esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Topics: Adenocarcinoma; Aged; Barrett Esophagus; Case-Control Studies; Diet; Esophageal Neoplasms; Esophagitis, Peptic; Female; Folic Acid; Humans; Male; Middle Aged; Risk Factors; Vitamin B Complex | 2013 |
Folate conjugated silk fibroin nanocarriers for targeted drug delivery.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Delivery Systems; Endocytosis; Female; Fibroins; Folic Acid; Humans; Microscopy, Electron, Transmission; Nanoparticles; Spectroscopy, Fourier Transform Infrared; Surface Properties | 2014 |
Targeted delivery of 5-fluorouracil to HT-29 cells using high efficient folic acid-conjugated nanoparticles.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Biological Transport; Cell Survival; Colonic Neoplasms; Cross-Linking Reagents; Diamines; Drug Carriers; Drug Compounding; Drug Delivery Systems; Fluorouracil; Folic Acid; HT29 Cells; Humans; Inhibitory Concentration 50; Kinetics; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2015 |
Folic acid supplementation promotes mammary tumor progression in a rat model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; bcl-2-Associated X Protein; Dietary Supplements; Disease Progression; Female; Folic Acid; Gene Expression; Humans; Mammary Neoplasms, Experimental; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Tumor Burden | 2014 |
Rho GTPases RhoA and Rac1 mediate effects of dietary folate on metastatic potential of A549 cancer cells through the control of cofilin phosphorylation.
Topics: Adenocarcinoma; Administration, Oral; Animals; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Survival; Cofilin 1; Dietary Supplements; Endoplasmic Reticulum; Epithelial-Mesenchymal Transition; Folic Acid; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methylation; Mice, SCID; Neoplasm Transplantation; p21-Activated Kinases; Phosphorylation; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Transport; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Signal Transduction | 2014 |
Polymorphisms of MTHFR and susceptibility to oesophageal adenocarcinoma in a Caucasian United Kingdom population.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Cell Differentiation; Chi-Square Distribution; Esophageal Neoplasms; Female; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Staging; Phenotype; Polymorphism, Genetic; Proportional Hazards Models; Risk Assessment; Risk Factors; Time Factors; United Kingdom; White People | 2014 |
Molecular imaging to identify tumor recurrence following chemoradiation in a hostile surgical environment.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Contrast Media; Fluorescein; Folate Receptor 1; Folic Acid; Humans; Lung Neoplasms; Mediastinum; Middle Aged; Molecular Imaging; Monitoring, Intraoperative; Neoplasm Recurrence, Local | 2014 |
Genetic variants in 3'-UTRs of methylenetetrahydrofolate reductase (MTHFR) predict colorectal cancer susceptibility in Koreans.
Topics: 3' Untranslated Regions; Adenocarcinoma; Aged; Colorectal Neoplasms; Female; Folic Acid; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Republic of Korea | 2015 |
3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.
Topics: 3' Untranslated Regions; Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; DEAD-box RNA Helicases; Female; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Karyopherins; Male; MicroRNAs; Middle Aged; Polymorphism, Single Nucleotide; ran GTP-Binding Protein; Republic of Korea; Ribonuclease III; Risk; RNA, Neoplasm; Tumor Burden | 2015 |
Theranostic, pH-Responsive, Doxorubicin-Loaded Nanoparticles Inducing Active Targeting and Apoptosis for Advanced Gastric Cancer.
Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Line, Tumor; Disease Progression; Doxorubicin; Drug Carriers; Drug Liberation; Ferric Compounds; Folic Acid; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Imaging; Magnetite Nanoparticles; Magnets; Male; Mice; Mice, Nude; Oleic Acid; Stomach Neoplasms; Theranostic Nanomedicine; Xenograft Model Antitumor Assays | 2015 |
In Vivo Antitumor Activity of Folate-Conjugated Cholic Acid-Polyethylenimine Micelles for the Codelivery of Doxorubicin and siRNA to Colorectal Adenocarcinomas.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Cholic Acid; Colorectal Neoplasms; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Folic Acid; Humans; Mice; Mice, Nude; Micelles; Nanoconjugates; Particle Size; Polyethylene Glycols; Polyethyleneimine; RNA, Small Interfering; Vascular Endothelial Growth Factor A | 2015 |
Folate receptor-targeted multimodal polymersomes for delivery of quantum dots and doxorubicin to breast adenocarcinoma: In vitro and in vivo evaluation.
Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cadmium Compounds; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Delivery Systems; Drug Liberation; Folic Acid; Folic Acid Transporters; Humans; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; NIH 3T3 Cells; Polyesters; Polyethylene Glycols; Quantum Dots; Tellurium; Tumor Burden | 2016 |
Impact of multicellular tumor spheroids as an in vivo‑like tumor model on anticancer drug response.
Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Fluorouracil; Folic Acid; HT29 Cells; Humans; Liposomes; Organoplatinum Compounds; Oxaliplatin; Spectrophotometry; Spheroids, Cellular | 2016 |
Prospective study of serum B vitamins levels and oesophageal and gastric cancers in China.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Cardia; China; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Flavin Mononucleotide; Folic Acid; Humans; Male; Middle Aged; Niacin; Proportional Hazards Models; Prospective Studies; Pyridoxal Phosphate; Riboflavin; Stomach Neoplasms; Vitamin B 12; Vitamin B Complex | 2016 |
The importance of mitochondrial folate enzymes in human colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinogenesis; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Humans; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mitochondria; Prognosis; Survival Analysis | 2017 |
Gastric cancer in relation to the intake of nutrients involved in one-carbon metabolism among MTHFR 677 TT carriers.
Topics: Adenocarcinoma; Case-Control Studies; Choline; Diet; DNA Methylation; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mexico; Middle Aged; Polymorphism, Restriction Fragment Length; Risk Factors; Stomach Neoplasms; Vitamin B 6 | 2009 |
Facile synthesis of multivalent folate-block copolymer conjugates via aqueous RAFT polymerization: targeted delivery of siRNA and subsequent gene suppression.
Topics: Acrylamides; Adenocarcinoma; Carrier Proteins; Cations; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Lung Neoplasms; Polymers; Receptors, Cell Surface; RNA, Small Interfering; Tumor Cells, Cultured | 2009 |
Major and prolonged response to pemetrexed in two cases of lung adenocarcinoma with bronchioloalveolar carcinoma features.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Aged; Antimetabolites, Antineoplastic; Bone Neoplasms; Cough; Disease Progression; Dyspnea; Folic Acid; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Neoplasm Staging; Neutropenia; Pemetrexed; Remission Induction; Renal Insufficiency; Smoking; Tomography, X-Ray Computed; Vitamin B 12 | 2009 |
Activity of pemetrexed against brain metastases in a patient with adenocarcinoma of the lung.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Brain Neoplasms; Chest Pain; Disease Progression; Dyspnea; Female; Folic Acid; Glutamates; Guanine; Headache; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasm Staging; Pemetrexed; Radiotherapy; Remission Induction; Smoking; Thoracic Surgery; Vitamin B 12 | 2009 |
Different histological types of non-small cell lung cancer have distinct folate and DNA methylation levels.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Cadherins; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Core Binding Factor Alpha 3 Subunit; DNA Methylation; Female; Folic Acid; Humans; Immunohistochemistry; Long Interspersed Nucleotide Elements; Lung Neoplasms; Male; Middle Aged | 2009 |
Targeting the efficacy of a dendrimer-based nanotherapeutic in heterogeneous xenograft tumors in vivo.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Proliferation; Dendrimers; Drug Carriers; Drug Delivery Systems; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Folic Acid; Humans; KB Cells; Methotrexate; Mice; Mice, Inbred NOD; Mice, SCID; Nanostructures; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Xenograft Model Antitumor Assays | 2010 |
Dietary folate and vitamin B6 are not associated with p53 mutations in esophageal adenocarcinoma.
Topics: Adenocarcinoma; Barrett Esophagus; Case-Control Studies; CpG Islands; Diet; Esophageal Neoplasms; Folic Acid; Gastroesophageal Reflux; Humans; Immunoenzyme Techniques; Mutation; Promoter Regions, Genetic; Surveys and Questionnaires; Tumor Suppressor Protein p53; Vitamin B 6 | 2010 |
Nanoparticulate delivery of novel drug combination regimens for the chemoprevention of colon cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Calcium; Cell Line, Tumor; Cell Survival; Chemoprevention; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Compounding; Drug Delivery Systems; Drug Synergism; Folic Acid; HT29 Cells; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2010 |
Effect of maternal and postweaning folic acid supplementation on mammary tumor risk in the offspring.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Carcinogens; Dietary Supplements; DNA Methylation; DNA Modification Methylases; Female; Folic Acid; Male; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley | 2011 |
High intake of folate from food sources is associated with reduced risk of esophageal cancer in an Australian population.
Topics: Adenocarcinoma; Adult; Aged; Alcohol Drinking; Australia; Barrett Esophagus; Betaine; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Dietary Supplements; Esophageal Neoplasms; Esophagus; Female; Folic Acid; Humans; Logistic Models; Male; Methionine; Middle Aged; Risk Factors; Smoking; Vitamin B Complex | 2011 |
Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenocarcinoma; Brazil; Colorectal Neoplasms; Female; Ferredoxin-NADP Reductase; Folic Acid; Genotype; Heterozygote; Humans; Male; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases; Pilot Projects; Polymorphism, Single Nucleotide; Risk; Thymidylate Synthase | 2011 |
Chemopreventive effect of epigallocatechin-3-gallate (EGCG) and folic acid on the N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastrointestinal cancer in rat model.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Folic Acid; Gastrointestinal Neoplasms; Hematinics; Male; Methylnitronitrosoguanidine; Rats; Rats, Wistar; Sarcoma; Treatment Outcome | 2011 |
Association of methylenetetrahydrofolate reductase C677T-A1298C polymorphisms with risk for esophageal adenocarcinoma, Barrett's esophagus, and reflux esophagitis.
Topics: Adenocarcinoma; Adult; Aged; Barrett Esophagus; Case-Control Studies; Esophageal Neoplasms; Esophagitis, Peptic; Female; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic | 2012 |
MTHFR polymorphisms, folate intake and carcinogen DNA adducts in the lung.
Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Case-Control Studies; DNA Adducts; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Humans; Lung; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Staging; Polymorphism, Genetic; Prognosis; Risk Factors; Smoking | 2012 |
Folic acid supplementary reduce the incidence of adenocarcinoma in a mouse model of colorectal cancer: microarray gene expression profile.
Topics: Adenocarcinoma; Animals; Colorectal Neoplasms; Disease Models, Animal; Female; Folic Acid; Mice; Mice, Inbred ICR; Random Allocation; Risk Factors; Transcriptome | 2011 |
Multicenter trial of EC145 in advanced, folate-receptor positive adenocarcinoma of the lung.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Drug Resistance, Neoplasm; Female; Folate Receptor 1; Folic Acid; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Oligopeptides; Prognosis; Survival Rate; Vinca Alkaloids | 2012 |
Folate receptor in adenocarcinoma and squamous cell carcinoma of the lung: potential target for folate-linked therapeutic agents.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Folate Receptor 1; Folic Acid; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Molecular Targeted Therapy; Tissue Array Analysis | 2013 |
Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Survival; Dendrimers; Folic Acid; Gold; Humans; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Tomography, X-Ray Computed | 2013 |
Dietary folate deficiency suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats.
Topics: Adenocarcinoma; Adenoma; Alkylating Agents; Animals; Body Weight; Diet; DNA Methylation; DNA, Neoplasm; Female; Folic Acid; Folic Acid Deficiency; Incidence; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 2003 |
Thymidine and hypoxanthine protection patterns of the folic acid-enhanced synergies for combinations of trimetrexate plus a polyglutamylatable inhibitor of purine or thymidylate synthesis against human ileocecal HCT-8 cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cecal Neoplasms; Cell Division; Drug Resistance, Multiple; Drug Synergism; Enzyme Inhibitors; Folic Acid; Glutamates; Hematinics; Humans; Hydroxymethyl and Formyl Transferases; Hypoxanthine; Ileal Neoplasms; Peptide Synthases; Phosphoribosylglycinamide Formyltransferase; Pyrimidines; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Trimetrexate; Tumor Cells, Cultured | 2003 |
Studies on the folic acid vitamins. VII. The effects of large doses of amethopterin in patients with cancer.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Folic Acid; Folic Acid Antagonists; Methotrexate; Neomycin; Neoplasms; Vitamins | 1962 |
In vivo efficacy of folate-targeted lipid-protamine-DNA (LPD-PEG-Folate) complexes in an immunocompetent syngeneic model for breast adenocarcinoma.
Topics: Adenocarcinoma; Animals; Carrier Proteins; DNA; Female; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Therapy; Humans; Immunocompetence; Lipid Metabolism; Liposomes; Mammary Neoplasms, Experimental; Mice; Polyethylene Glycols; Protamines; Receptors, Cell Surface; Thymidine Kinase | 2004 |
Effects of dietary folate on the development and progression of mammary tumors in rats.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Diet; Female; Folic Acid; Folic Acid Deficiency; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 2005 |
5,10-Methylenetetrahydrofolate reductase polymorphisms and the risk of pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Alcohol Drinking; Case-Control Studies; Female; Folic Acid; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Pancreatic Neoplasms; Polymorphism, Genetic; Risk Factors; Smoking | 2005 |
Chemopreventive effects of rofecoxib and folic acid on gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Cell Proliferation; Folic Acid; Gastric Mucosa; Lactones; Male; Methylnitronitrosoguanidine; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Stomach Neoplasms; Sulfones | 2006 |
The effect of folic acid on porphyrin synthesis in tumors and normal skin of mice treated with 5-aminolevulinic acid or methyl 5-aminolevulinate.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Colonic Neoplasms; Female; Folic Acid; Humans; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Nude; Photochemotherapy; Porphyrins; Sensitivity and Specificity; Skin; Spectrometry, Fluorescence; Time Factors; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2006 |
Oil-encapsulating PEO-PPO-PEO/PEG shell cross-linked nanocapsules for target-specific delivery of paclitaxel.
Topics: Adenocarcinoma; Apoptosis; Carrier Proteins; Cell Line, Tumor; Cross-Linking Reagents; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Iodized Oil; Nanocapsules; Oils; Paclitaxel; Polyethylene Glycols; Propylene Glycols; Receptors, Cell Surface; Solubility | 2007 |
Folate status and S-adenosylmethionine/S-adenosylhomocysteine ratio in colorectal adenocarcinoma in humans.
Topics: Adenocarcinoma; Aged; Colon; Colorectal Neoplasms; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Intestinal Mucosa; Male; Nutritional Status; S-Adenosylhomocysteine; S-Adenosylmethionine | 2008 |
Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case control study.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoma, Large Cell; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Case-Control Studies; Female; Folic Acid; Genetic Predisposition to Disease; Humans; Japan; Lung Neoplasms; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Random Allocation; Risk Factors | 2007 |
Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.
Topics: Adenocarcinoma; Animals; Binding, Competitive; Blood Proteins; Carrier Proteins; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Protein Binding; Pterins; Receptors, Cell Surface; Time Factors; Tumor Burden; Vinca Alkaloids; Xenograft Model Antitumor Assays | 2007 |
The effect of derivatives of folic acid on the fluorodeoxyuridylate-thymidylate synthetase covalent complex in human colon xenografts.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Deoxyuracil Nucleotides; Female; Fluorodeoxyuridylate; Folic Acid; Homocysteine; Humans; Methyltransferases; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Rectal Neoplasms; Tetrahydrofolates; Thymidylate Synthase; Transplantation, Heterologous; Vitamin B 12 | 1982 |
Prevention of isoniazid tumorigenicity by antitoxicants of isoniazid in Swiss mice.
Topics: Adenocarcinoma; Ammonia; Animals; Arginine; Folic Acid; Isoniazid; Kidney; Liver; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Protein Biosynthesis; Pyridoxine; Sodium Glutamate | 1980 |
[Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--l-leucovorin factors enhancing cytotoxic activity of 5-fluorouracil].
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Folic Acid; Humans; Leucovorin; Tegafur; Tumor Cells, Cultured; Uracil | 1995 |
New therapeutic strategies for patients with gastrointestinal malignancies using biochemical modulation of fluorouracil.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Colonic Neoplasms; Fatal Outcome; Fluorouracil; Folic Acid; Folic Acid Antagonists; Gastrointestinal Neoplasms; Gene Expression Regulation, Enzymologic; Humans; Interferon-alpha; Leucovorin; Liver Neoplasms; Male; Middle Aged; Prognosis; Quinazolines; RNA, Messenger; RNA, Neoplasm; Thymidylate Synthase | 1995 |
Inhibition of apical but not basolateral endocytosis of ricin and folate in Caco-2 cells by cytochalasin D.
Topics: Actin Cytoskeleton; Adenocarcinoma; Animals; Cell Line; Cell Polarity; Colonic Neoplasms; Cytochalasin D; Depression, Chemical; Dogs; Endocytosis; Folic Acid; Humans; Kidney; Microvilli; Neoplasm Proteins; Ricin; Tumor Cells, Cultured | 1994 |
Effect of purine synthesis inhibition on WiDr spheroids in vitro or on WiDr or colon 38 tumors in vivo. Complete growth inhibition but not regression.
Topics: Acyltransferases; Adenocarcinoma; Animals; Cell Division; Colonic Neoplasms; Folic Acid; Humans; Hydroxymethyl and Formyl Transferases; Mice; Mice, Inbred C57BL; Phosphoribosylglycinamide Formyltransferase; Purines; Tetrahydrofolates; Tumor Cells, Cultured | 1994 |
New anti-lung-cancer antibody cluster 12 reacts with human folate receptors present on adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Blotting, Western; Breast Neoplasms; Bronchi; Carcinoma, Small Cell; Carrier Proteins; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Hybridomas; Immunoglobulin G; Immunohistochemistry; Lung Neoplasms; Mice; Mice, Inbred BALB C; Organ Specificity; Receptors, Cell Surface | 1994 |
Ternary complex formation and reduced folate in surgical specimens of human adenocarcinoma tissues.
Topics: Adenocarcinoma; Colorectal Neoplasms; Culture Techniques; Fluorouracil; Folic Acid; Humans; Leucovorin; Lymph Nodes; Phosphorylation; Stomach Neoplasms; Tetrahydrofolates; Thymidine Kinase; Thymidylate Synthase | 1993 |
Augmentation of the therapeutic activity of lometrexol -(6-R)5,10-dideazatetrahydrofolate- by oral folic acid.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antimetabolites, Antineoplastic; Dogs; Drug Screening Assays, Antitumor; Drug Synergism; Female; Folic Acid; Folic Acid Antagonists; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Tetrahydrofolates | 1996 |
Relationship of plasma folic acid and status of DNA methylation in human gastric cancer.
Topics: Adenocarcinoma; Blotting, Southern; Carcinoma, Signet Ring Cell; DNA Methylation; DNA, Neoplasm; Female; Folic Acid; Genes, myc; Genes, ras; Humans; Male; Middle Aged; Stomach Neoplasms | 1997 |
Epithelial cell folate depletion occurs in neoplastic but not adjacent normal colon mucosa.
Topics: Adenocarcinoma; Adenomatous Polyps; Colon; Colonic Neoplasms; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Mucosa; Reference Values | 1997 |
Relationship between vitamin and calcium supplement use and colon cancer.
Topics: Adenocarcinoma; Adult; Calcium; Case-Control Studies; Colonic Neoplasms; Data Collection; Dietary Supplements; Female; Folic Acid; Humans; Logistic Models; Male; Middle Aged; Risk; Vitamins | 1997 |
A folate binding protein in ascitic fluid, serum and ovarian tissue of patients with ovarian adenocarcinoma immunoreacts with antibodies against human milk folate binding protein.
Topics: Adenocarcinoma; Animals; Antibodies; Ascitic Fluid; Carrier Proteins; Chromatography, Gel; Enzyme-Linked Immunosorbent Assay; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Immunoblotting; Immunohistochemistry; Milk Proteins; Milk, Human; Molecular Weight; Ovarian Neoplasms; Ovary; Rabbits; Receptors, Cell Surface | 1998 |
Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5,4,6][1,4]thiazin -6-yl)-(S)-ethyl]-2,5-thienoylamino-L-glutamic acid (AG
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Drug Resistance, Multiple; Drug Synergism; Folic Acid; Folic Acid Antagonists; Glutamates; Head and Neck Neoplasms; Humans; Hydroxymethyl and Formyl Transferases; Kinetics; Lung Neoplasms; Phosphoribosylglycinamide Formyltransferase; Pyrimidines; Trimetrexate; Tumor Cells, Cultured | 1999 |
[Value of multivitamin preparations and folic acid in primary prevention of colonic cancer in women].
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Diet; Dietary Fiber; Female; Folic Acid; Follow-Up Studies; Humans; Middle Aged; Primary Prevention; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Sex Factors; Time Factors; Vitamins | 1999 |
Determination of endogenous formaldehyde in plants (fruits) bound to L-arginine and its relation to the folate cycle, photosynthesis and apoptosis.
Topics: Adenocarcinoma; Apoptosis; Arginine; Chromatography, High Pressure Liquid; Colonic Neoplasms; Folic Acid; Formaldehyde; Humans; Photosynthesis; Plants; Tumor Cells, Cultured | 1998 |
Cellulose and calcium lower the incidence of chemically-induced colon tumors in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Calcium, Dietary; Carcinogens; Cellulose; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Disease Models, Animal; Folic Acid; Male; Random Allocation; Rats; Rats, Inbred F344 | 1999 |
Multivitamins, folate, and colon cancer.
Topics: Adenocarcinoma; Adult; Colonic Neoplasms; Dietary Supplements; Female; Folic Acid; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Risk; Vitamins | 2001 |
Folate deficiency reduces the development of colorectal cancer in rats.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Colorectal Neoplasms; Folic Acid; Folic Acid Deficiency; Intestinal Neoplasms; Male; Rats; Rats, Sprague-Dawley | 2000 |
Low serum and red blood cell folate are moderately, but nonsignificantly associated with increased risk of invasive cervical cancer in U.S. women.
Topics: Adenocarcinoma; Adult; Aged; Antibodies, Viral; Bacteriological Techniques; Carcinoma, Squamous Cell; Case-Control Studies; Erythrocytes; Female; Folic Acid; Humans; Interviews as Topic; Middle Aged; Neoplasm Invasiveness; Odds Ratio; Papillomaviridae; Papillomavirus Infections; Regression Analysis; Risk Factors; Tumor Virus Infections; United States; Uterine Cervical Neoplasms | 2001 |
Folic-acid-mediated inhibition of human colon-cancer cell growth.
Topics: Adenocarcinoma; Animals; Caco-2 Cells; Cell Division; Cell Transformation, Neoplastic; Colonic Neoplasms; Disease Models, Animal; DNA Methylation; Folic Acid; Humans; Tetrahydrofolates | 2001 |
10-formyltetrahydrofolate dehydrogenase, one of the major folate enzymes, is down-regulated in tumor tissues and possesses suppressor effects on cancer cells.
Topics: Adenocarcinoma; Cell Division; Cell Line, Transformed; Down-Regulation; Folic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Liver Regeneration; Lung Neoplasms; Male; Oxidoreductases Acting on CH-NH Group Donors; Prostatic Neoplasms; RNA, Messenger; Tumor Cells, Cultured | 2002 |
Recurrent aphthae: treatment with vitamin B12, folic acid, and iron.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Anemia, Pernicious; Cecal Neoplasms; Child; Colitis; Crohn Disease; Diverticulum, Colon; Female; Folic Acid; Folic Acid Deficiency; Humans; Iron; Iron Deficiencies; Malabsorption Syndromes; Male; Middle Aged; Proctitis; Recurrence; Stomatitis, Aphthous; Vitamin B 12; Vitamin B 12 Deficiency | 1975 |
Synthesis and biological evaluation of N alpha-(5-deaza-5,6,7,8-tetrahydropteroyl)-L-ornithine.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Survival; Folic Acid; Folic Acid Antagonists; Humans; Liver; Peptide Synthases; Polyglutamic Acid; Swine; Tumor Cells, Cultured | 1992 |
Design and synthesis of novel 6,7-imidazotetrahydroquinoline inhibitors of thymidylate synthase using iterative protein crystal structure analysis.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Binding Sites; Cell Division; Crystallization; Drug Design; Escherichia coli; Folic Acid; Humans; Imidazoles; Leukemia; Leukemia L1210; Mice; Molecular Structure; Quinolines; Thymidylate Synthase; Tumor Cells, Cultured | 1992 |
Interaction of gamma interferon and 5-fluorouracil in the H630 human colon carcinoma cell line.
Topics: Adenocarcinoma; Cell Division; Colonic Neoplasms; DNA; Drug Interactions; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Folic Acid; Humans; Interferon-gamma; RNA; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tumor Cells, Cultured | 1990 |
Mutation(s) of the thymidylate synthase gene of human adenocarcinoma cells causes a thymidylate synthase-negative phenotype that can be attenuated by exogenous folates.
Topics: Adenocarcinoma; Animals; Base Sequence; Cell Division; Cell Line; Colonic Neoplasms; Folic Acid; Humans; Kinetics; Leucovorin; Mice; Mice, Nude; Mitotic Index; Molecular Sequence Data; Mutation; Neoplasm Transplantation; Oligodeoxyribonucleotides; Phenotype; Polymerase Chain Reaction; Thymidylate Synthase; Transplantation, Heterologous; Tumor Stem Cell Assay | 1992 |
Interaction between 5-fluorouracil, [6RS]leucovorin, and recombinant human interferon-alpha 2a in cultured colon adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Survival; Colonic Neoplasms; Drug Synergism; Fluorouracil; Folic Acid; Interferon Type I; Leucovorin; Quinazolines; Recombinant Proteins; Thymidylate Synthase; Tumor Cells, Cultured | 1991 |
A case-control study of serum folate levels and invasive cervical cancer.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Case-Control Studies; Contraceptives, Oral; Female; Folic Acid; Humans; Middle Aged; Parity; Pregnancy; Risk Factors; South America; Uterine Cervical Neoplasms | 1991 |
Role for cytosolic folate-binding proteins in the compartmentation of endogenous tetrahydrofolates and the 5-formyl tetrahydrofolate-mediated enhancement of 5-fluoro-2'-deoxyuridine antitumor activity in vitro.
Topics: Adenocarcinoma; Animals; Carrier Proteins; Cell Division; Chromatography, Gel; Colonic Neoplasms; Floxuridine; Folic Acid; Humans; Leucovorin; Leukemia L1210; Tetrahydrofolates | 1990 |
Chemosensitivity and DNA content as prognostic factors in ovarian cancer: preliminary results.
Topics: Adenocarcinoma; Aged; Colony-Forming Units Assay; Doxorubicin; Female; Fluorouracil; Folic Acid; Humans; In Vitro Techniques; Middle Aged; Ovarian Neoplasms; Ploidies; Prognosis; Tumor Stem Cell Assay | 1990 |
Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft.
Topics: Adenocarcinoma; Colonic Neoplasms; Deoxyuracil Nucleotides; Fluorodeoxyuridylate; Folic Acid; Humans; In Vitro Techniques; Kinetics; Pteroylpolyglutamic Acids; Structure-Activity Relationship; Tetrahydrofolates; Thymidylate Synthase | 1989 |
The efficacy of 5-fluorouracil in human colorectal cancer is not enhanced by thymidylate synthetase inhibition with CB3717 (N10-propargyl-5,8 dideazafolic acid).
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Folic Acid; Humans; Middle Aged; Quinazolines; Rectal Neoplasms; Thymidylate Synthase | 1988 |
Distribution and metabolism of calcium leucovorin in normal and tumor tissue.
Topics: Adenocarcinoma; Animals; Carbon-Nitrogen Ligases; Colonic Neoplasms; Folic Acid; Leucovorin; Ligases; Liver; Mice; Mice, Inbred C57BL; Reference Values | 1988 |
Selectivity of CF and 5-fluorouracil: critical role of polyglutamylation.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Fluorouracil; Folic Acid; Humans; Leucovorin; Mice; Neoplasm Transplantation; Pteroylpolyglutamic Acids; Thymidylate Synthase; Transplantation, Heterologous | 1988 |
Characteristics of thymidylate synthase purified from a human colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Deoxyuracil Nucleotides; Folic Acid; Humans; Kinetics; Mice; Stereoisomerism; Thymidylate Synthase; Transplantation, Heterologous | 1988 |