Page last updated: 2024-08-17

folic acid and Acute Kidney Injury

folic acid has been researched along with Acute Kidney Injury in 107 studies

Research

Studies (107)

TimeframeStudies, this research(%)All Research%
pre-199023 (21.50)18.7374
1990's1 (0.93)18.2507
2000's16 (14.95)29.6817
2010's45 (42.06)24.3611
2020's22 (20.56)2.80

Authors

AuthorsStudies
Chen, M; Gao, Y; Liang, H; Liu, B; Nie, J; Wen, X; Zhong, C1
Abu-Elsaad, NM; Elsayed, MS; Nader, MA1
Yan, LJ1
Cannata-Ortiz, P; Carrasco, S; Fontecha-Barriuso, M; Guerrero-Mauvecin, J; Lopez-Diaz, AM; Martin-Sanchez, D; Mendez-Barbero, N; Ortiz, A; Ruiz-Ortega, M; Saiz, ML; Sanchez-Niño, MD; Sanz, AB1
Abdelrahman, RS; Abdelsalam, RA; Zaghloul, MS1
Bai, Y; Cheng, G; Du, B; Jiao, Q; Wang, Y; Yu, L; Zhao, M1
Gao, L; Hu, XR; Huang, YB; Jiang, L; Liu, XQ; Wang, X; Wu, YG; Zeng, HX; Zhu, W1
Gan, W; Lei, J; Sheng, J; Song, J; Yang, Y1
Bartos, K; Moor, MB1
Al-Suraimi, A; Beamish, JA; Chowdhury, M; Dressler, GR; Ference-Salo, JT; McElliott, MC; Soofi, A; Telang, AC1
Cui, B; Hou, X; Liu, N; Qiu, A; Zhuang, S1
Chen, D; Chen, Z; Dong, S; Fan, Y; Liang, D; Xia, Y; Yang, F; Yang, X; Zeng, C; Zhang, M1
Bolevich, S; Jakovljevic, V; Jeremic, J; Matic, S; Nikolic, T; Petrovic, D; Radonjic, K; Srejovic, I; Turnic, TN; Zivkovic, V1
Gao, H; Huang, S; Jia, Z; Yang, Y; Zhang, W; Zhang, Y1
Hendry, BM; Hung, G; Newbury, LJ; Sharpe, CC; Wang, JH1
Gai, Z; Kullak-Ublick, GA; Samodelov, SL; Visentin, M1
Abdelrahman, RS; Zaghloul, MS1
Bastepe, M; Cui, Q; He, Q; Matthias, J; Plagge, A; Shumate, LT1
Cannata, P; Castelo-Branco, RC; Córdoba-David, G; Duro-Castano, A; González-Guerrero, C; Ortiz, A; Ramos, AM; Sanz, AB; Vicent, MJ1
Aparicio-Trejo, OE; Avila-Rojas, SH; Hernández-Pando, R; León-Contreras, JC; Martínez-Klimova, E; Pedraza-Chaverri, J; Rojas-Morales, P; Sánchez-Lozada, LG; Tapia, E1
Akgun, E; Boyacioglu, M; Kum, S1
Chen, M; Chen, X; Guo, L; Wang, F; Wang, S; Wu, B; Xu, H; Yang, D; Yu, F; Zhang, T; Zhou, C1
El-Kashef, DH; Ezzat, DM; Soliman, AM1
Cao, P; Chang, Y; Duan, X; Fan, Y; Han, B; Hao, Q; Li, D; Liu, B; Liu, M; Liu, X; Meng, Y; Nakai, A; Song, Z; Tan, K; Xu, X1
Ayvaz, Ş; Cho, SJ; Choi, HS; Choy, HE; Dooley, S; Fliser, D; Jung, YS; Kim, DH; Kim, DK; Kim, HS; Kim, J; Kim, YH; Lee, CH; Lee, IK; Lim, D; Na, SY; Nittka, S; Radhakrishnan, K; Schunk, SJ; Speer, T1
Fu, P; Guo, F; Huang, R; Li, L; Liu, J; Ma, L; Tan, Z; Tao, S; Zeng, X1
Cannata-Ortiz, P; Carrasco, S; Egido, J; Fontecha-Barriuso, M; Linkermann, A; Martin-Sanchez, D; Mässenhausen, AV; Ortiz, A; Ruiz-Ortega, M; Sanchez-Niño, MD; Sanz, AB1
Datzmann, T; Reinelt, H; Schröppel, B; Träger, K; von Freyberg, P1
Axelrod, J; Durlacher-Betzer, K; Hassan, A; Levi, R; Naveh-Many, T; Silver, J1
Arias, M; Cannata-Ortiz, P; Egido, J; Gómez-Alamillo, C; González-Guerrero, C; Mezzano, S; Morgado-Pascual, JL; Ortiz, A; Ramos, AM; Ramos-Barron, MA; Ruiz-Ortega, M1
Jiang, K; Lerman, LO; Macura, SI; Mishra, PK; Ponzo, TA; Tang, H1
Adamowicz, K; Foresto-Neto, O; Honarpisheh, M; Koehler, P; Koziel, J; Kraft, F; Lech, M; Potempa, J; Steiger, S; von Rauchhaupt, E1
Bayliss, G; Guan, Y; Tolbert, T; Zang, X; Zhao, TC; Zhou, X; Zhuang, S1
Aparicio-Trejo, OE; Briones-Herrera, A; Hernández-Pando, R; León-Contreras, JC; Pedraza-Chaverri, J; Reyes-Fermín, LM; Sánchez-Lozada, LG; Tapia, E1
Fu, H; Hong, X; Hou, FF; Liao, J; Lin, L; Liu, Y; Zhou, D; Zhu, H1
Cabello, R; Cannata-Ortiz, P; Carrasco, S; Fontecha-Barriuso, M; Gómez, MJ; Gonzalez-Enguita, C; Martín-Sánchez, D; Martinez-Moreno, JM; Monsalve, M; Ortiz, A; Ruiz-Andrés, O; Ruiz-Ortega, M; Sánchez-Niño, MD; Sanchez-Ramos, C; Sanz, AB1
Dworkin, LD; Flickinger, B; Ge, Y; Gong, R; Jiang, C; Liu, Z; Lu, M; Malhotra, DK; Qiao, Y; Wang, P1
Bishop, JV; Kellum, JA; Nolin, TD; Peng, ZY; Wang, HZ; Wen, XY; Zhou, F1
Christov, M; Goltzman, D; Havasi, A; Jüppner, H; Leaf, DE; Pajevic, PD; Pereira, RC; Waikar, SS; Wolf, M1
Schnellmann, RG; Stallons, LJ; Whitaker, RM; Wills, LP1
Cao, J; Chen, J; Goligorsky, MS; Lin, CH; Maizel, J; Rabadi, M; Ratliff, B; Tanokuchi, R; Vasko, R; Xavier, S; Zhang, F1
Schnellmann, RG; Stallons, LJ; Whitaker, RM1
Bayliss, G; Gong, R; Tang, J; Yan, H; Yan, Y; Zhao, TC; Zhuang, S1
Câmara, NO; Corrêa, RR; Glória, MA; Guimarães, CS; Helmo, FR; Machado, JR; Pereira Júnior, CD; Pucci, KR; Reis, MA; Rocha, LB; Rocha, LP; Rodrigues, AR1
Kumar, D; Puri, S; Puri, V; Singla, SK1
Boruc, O; Bruce-Cobbold, C; Caplin, B; Cutillas, P; Dormann, D; Faull, P; Grossman, RC; Khadayate, S; Leiper, J; Mas, VR; Nitsch, DD; Norman, JT; Tomlinson, JA; Wang, Z; Wheeler, DC; Wilcox, CS1
Durlacher, K; Hassan, A; Levi, R; Naveh-Many, T; Silver, J1
Elewa, YH; Ichii, O; Kimura, J; Kon, Y; Nakamura, T; Otsuka-Kanazawa, S; Shiozuru, D1
Burgos-Silva, M; Câmara, NO; Cenedeze, MA; Costa, PB; Donizetti-Oliveira, C; Hiyane, MI; Pacheco-Silva, A; Semedo-Kuriki, P1
Bijol, V; Craciun, FL; Gerlach, CV; Kissick, HT; Pellegrini, KL; Ramachandran, K; Vaidya, VS1
Gong, R; Jiang, C; Jin, B; Shao, Q; Xu, B; Zhang, M1
Brenneman, K; Campanholle, G; Chockalingam, P; Evans, SM; Fleming, M; Homer, B; Karim, R; Lin, LL; Nagiec, EE; Neubert, H; O'Neil, SP; Pullen, N; Sharif, MN; Syed, J; Wang, J; Zhan, Y1
Jiang, C; Jin, B; Shao, Q; Xu, B; Yan, X; Zhang, M; Zhu, W1
Cocchiaro, P; Fox, C; Howarth, R; Moles, A; Pavone, LM; Sheerin, NS; Situmorang, GR; Tregidgo, NW; Wood, KM1
Cannata-Ortiz, P; Carrasco, S; Egido, J; Linkermann, A; Martin-Sanchez, D; Ortiz, A; Poveda, J; Ruiz Ortega, M; Ruiz-Andres, O; Sanchez-Niño, MD; Sanz, AB1
Gong, R; Jiang, C; Shao, Q; Xu, B; Yan, X; Zhang, M; Zhu, W1
Chen, S; Chen, X; Chen, Z; Mao, Z; Mei, C; Ruan, M; Wu, M; Yang, B; Zhang, L1
Ali, I; Bingham, V; Brazil, DP; Church, RH; Dunne, PD; Goldschmeding, R; Hombrebueno, JR; Kok, HM; Krishnakumar, A; Lavin, D; Martin, F; Tate, M1
Basile, DP1
Choi, MK; Chung, SJ; Jin, QR; Kim, DD; Shim, CK; Shim, WS; Song, IS; Tian, GY; Yang, SG1
Gupta, A; Puri, S; Puri, V; Sharma, R1
Kolatsi-Joannou, M; Long, DA; Price, KL; Winyard, PJ1
Bishop, JV; Kellum, JA; Peng, ZY; Rimmelé, T; Wang, HZ; Wen, XY1
Bishop, JV; Chandra, S; Filippi, MD; Kellum, JA; Murugan, R; Singbartl, K; Wen, X1
Bishop, JV; Chedwick, LR; Kellum, JA; Li, Y; Peng, Z; Singbartl, K; Wang, H; Wen, X1
Igarashi, P; Li, Y; Lin, L; Liu, Y; Zhou, D; Zhou, L1
Chiu, SC; Ding, DC; Fang, TC; Pang, CY; Tsai, RK1
Bayliss, G; He, S; Liu, N; Zhuang, S1
Ardura, JA; Esbrit, P; Ortiz, A; Sanz, AB1
Egido, J; Gómez-Garre, D; Justo, P; Lorz, C; Mezzano, S; Ortiz, A; Sanz, A1
GRAESBECK, R; HASAN, J; KVIST, G1
Bae, HY; Choi, DH; Choi, JS1
Clouthier, SG; Ferrara, JL; Humes, HD; Szczypka, MS; Westover, AJ1
Barat, A; Bosch, RJ; Esbrit, P; Gazapo, R; González, L; Izquierdo, A; Ortega, A; Rámila, D1
Chen, A; Cheng, CW; Ka, SM; Lee, WH; Lin, YF; Rifai, A; Shui, HA1
Cao, Q; Hao, L; Qiu, Y; Sun, Z; Wan, B; Wang, H; Zhang, Y; Zhu, T1
Egido, J; Justo, P; Lorz, C; Ortiz, A; Sanchez-Niño, MD; Sanz, AB; Winkles, JA1
Betz, I; Conway, EM; De Vriese, A; Kindt, N; Menzebach, A; Van de Wouwer, M1
Oken, DE1
Keogh, JA; Lawlor, E; Watson, A1
Korfel, A; Krackhardt, A; Schwartz, S; Thiel, E1
Catalán, MP; Danoff, TM; Egido, J; Lorz, C; Neilson, EG; Ortiz, A; Yamasaki, Y1
Gourgiotis, D; Kavazarakis, E; Messaritaki, A; Moustaki, M; Nakopoulou, L; Nicolaidou, P; Tzaki, M; Zeis, MP; Zeis, PM1
Ishida, A; Katayama, M; Kobayashi, S; Miura, S; Nakabayashi, I; Nishiyama, J; Nogami, H; Tajima, O1
Khajehdehi, P1
Bosch, RJ; Egido, J; Esbrit, P; Fernández-Agulló, T; Gazapo, R; Largo, R; Ortega, A; Santos, S1
Burm, JP; Choi, JS; Lee, JH1
Bonar, RA; Mullin, EM; Paulson, DF1
Dubach, U; Schmidt, U1
Dieker, P; Maykemper, B; Zimmermann, HD1
Birbaumer, A; Brunner, FP; Dubach, UC; Huguenin, ME; Schmidt, U; Thiel, G; Thorhorst, J1
Stöcker, E1
Aizawa, K; Ino, Y; Kan, K; Kuroda, S; Wada, T1
Bonar, RA; Kane, RD; Mullin, EM; Paulson, DF1
Schubert, GE1
Colvin, BT; Colvin, MP; Ibbotson, RM1
Calvet, JP; Chadwick, LJ; Cowley, BD; Grantham, JJ1
Calvert, AH; Cantwell, BM; Harris, AL; Kaye, SB; Macaulay, V; Milsted, RA; Smith, IE1
Helmchen, U; Kirchertz, EJ; Kneissler, U; Reifferscheid, P1
Goldsmith, HJ; Reid, HA; Wright, FK1
Dubach, UC; Huguenin, M; Schmidt, U; Torhorst, J1
Geary, CG; Mallick, NP1
Dubach, UC; Jösch, W; Schlumpf, V; Schmidt, U1
Fischbach, H; Helmchen, U; Kneissler, U; Reifferscheid, P; Schmidt, U1
Otten, G; Schubert, GE; Sinner, E1
Brade, W; Propping, P1
Hoffbrand, AV; Sevitt, LH1

Reviews

4 review(s) available for folic acid and Acute Kidney Injury

ArticleYear
Folic acid-induced animal model of kidney disease.
    Animal models and experimental medicine, 2021, Volume: 4, Issue:4

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Folic Acid; Kidney; Renal Insufficiency, Chronic

2021
Renal Reabsorption of Folates: Pharmacological and Toxicological Snapshots.
    Nutrients, 2019, Oct-02, Volume: 11, Issue:10

    Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Homeostasis; Humans; Kidney; Nutritional Status; Polycystic Kidney, Autosomal Dominant; Renal Insufficiency, Chronic; Renal Reabsorption; Risk Assessment; Risk Factors

2019
Hemodynamic basis for human acute renal failure (vasomotor nephropathy).
    The American journal of medicine, 1984, Volume: 76, Issue:4

    Topics: Acute Kidney Injury; Adult; Animals; Female; Folic Acid; Glomerular Filtration Rate; Glycerol; Humans; Kidney Cortex; Mercuric Chloride; Mercury; Mercury Poisoning; Methemoglobin; Norepinephrine; Rats; Renal Artery Obstruction; Vasomotor System

1984
Folate deficiency in acutely ill patients.
    Irish journal of medical science, 1983, Volume: 152, Issue:2

    Topics: Acute Disease; Acute Kidney Injury; Aged; Folic Acid; Folic Acid Deficiency; Humans; Male; Pancytopenia; Sepsis

1983

Other Studies

103 other study(ies) available for folic acid and Acute Kidney Injury

ArticleYear
IRF-4 deficiency reduces inflammation and kidney fibrosis after folic acid-induced acute kidney injury.
    International immunopharmacology, 2021, Volume: 100

    Topics: Acute Kidney Injury; Animals; Cell Transdifferentiation; Cells, Cultured; Cytokines; Disease Models, Animal; Disease Progression; Extracellular Matrix Proteins; Fibrosis; Folic Acid; Inflammation Mediators; Interferon Regulatory Factors; Kidney; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; Nephritis; Renal Insufficiency, Chronic

2021
The NLRP3 inhibitor dapansutrile attenuates folic acid induced nephrotoxicity via inhibiting inflammasome/caspase-1/IL axis and regulating autophagy/proliferation.
    Life sciences, 2021, Nov-15, Volume: 285

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Autophagy; Biomarkers; Caspase 1; Cell Proliferation; Folic Acid; Inflammasomes; Interleukin-18; Interleukin-1beta; Ki-67 Antigen; Kidney; Male; Nitriles; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley

2021
Bone Marrow-Derived RIPK3 Mediates Kidney Inflammation in Acute Kidney Injury.
    Journal of the American Society of Nephrology : JASN, 2022, Volume: 33, Issue:2

    Topics: Acute Kidney Injury; Animals; Bone Marrow; Cytokine TWEAK; Disease Models, Animal; Folic Acid; Humans; Inflammation; Interleukin-6; Jurkat Cells; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Receptor-Interacting Protein Serine-Threonine Kinases; RNA, Messenger; Transplantation Chimera; Up-Regulation

2022
Beneficial effect of trimetazidine on folic acid-induced acute kidney injury in mice: Role of HIF-1α/HO-1.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:5

    Topics: Acute Kidney Injury; Animals; Creatinine; Female; Folic Acid; Heme Oxygenase-1; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Membrane Proteins; Mice; Oxidative Stress; Signal Transduction; Trimetazidine

2022
Folic acid-targeted pluronic F127 micelles improve oxidative stress and inhibit fibrosis for increasing AKI efficacy.
    European journal of pharmacology, 2022, Sep-05, Volume: 930

    Topics: Acute Kidney Injury; Apoptosis; Cisplatin; Curcumin; Fibrosis; Folic Acid; Humans; Micelles; Oxidative Stress; Poloxamer; Resveratrol

2022
Melatonin Alleviates Acute Kidney Injury by Inhibiting NRF2/Slc7a11 Axis-Mediated Ferroptosis.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Acute Kidney Injury; Animals; Ferroptosis; Folic Acid; Hypoxia; Melatonin; Mice; NF-E2-Related Factor 2; Reperfusion Injury

2022
Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Acute Kidney Injury; Animals; Antioxidants; Cisplatin; Ferroptosis; Folic Acid; Humans; Iron; Lipid Peroxides; Mice; Mitochondria; Reactive Oxygen Species; Reperfusion Injury

2022
FGFR regulator Memo1 is dispensable for FGF23 expression by osteoblasts during folic acid-driven kidney injury.
    Physiological reports, 2023, Volume: 11, Issue:6

    Topics: Acute Kidney Injury; Animals; Bone Diseases; Female; Fibroblast Growth Factors; Folic Acid; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Male; Mice; Osteoblasts; X-Ray Microtomography

2023
High-throughput image analysis with deep learning captures heterogeneity and spatial relationships after kidney injury.
    Scientific reports, 2023, 04-19, Volume: 13, Issue:1

    Topics: Acute Kidney Injury; Animals; Deep Learning; Folic Acid; Humans; Kidney; Mice; Models, Animal

2023
Pharmacological inhibition of the mixed lineage leukemia 1-menin interaction aggravates acute kidney injury induced by folic acid and ischemia-reperfusion in mice.
    American journal of physiology. Renal physiology, 2023, 11-01, Volume: 325, Issue:5

    Topics: Acute Kidney Injury; Animals; Creatinine; ErbB Receptors; Folic Acid; Histones; Ischemia; Leukemia; Lysine; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein; Reperfusion; Reperfusion Injury; Transcription Factors

2023
Krüppel-like Factor 15 Suppresses Ferroptosis by Activating an NRF2/GPX4 Signal to Protect against Folic Acid-Induced Acute Kidney Injury.
    International journal of molecular sciences, 2023, Sep-26, Volume: 24, Issue:19

    Topics: Acute Kidney Injury; Animals; Ferroptosis; Folic Acid; Humans; Kruppel-Like Transcription Factors; Mice; NF-E2-Related Factor 2

2023
The influence of folic acid-induced acute kidney injury on cardiac function and redox status in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2020, Volume: 393, Issue:1

    Topics: Acute Kidney Injury; Animals; Coronary Circulation; Folic Acid; Heart; Heart Rate; Hydrogen Peroxide; Kidney; Male; Myocardium; Nitrites; Oxidation-Reduction; Oxidative Stress; Rats, Wistar; Superoxides; Thiobarbituric Acid Reactive Substances; Ventricular Function

2020
Inhibition of Mitochondrial Complex I Aggravates Folic Acid-Induced Acute Kidney Injury.
    Kidney & blood pressure research, 2019, Volume: 44, Issue:5

    Topics: Acute Kidney Injury; Animals; Electron Transport Complex I; Folic Acid; Humans; Male; Mice; Mitochondria; Oxidative Stress

2019
Inhibition of Kirsten-Ras reduces fibrosis and protects against renal dysfunction in a mouse model of chronic folic acid nephropathy.
    Scientific reports, 2019, 09-30, Volume: 9, Issue:1

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Fibrosis; Folic Acid; Gene Knockdown Techniques; Jagged-1 Protein; Kidney; Male; Mice; Polymerase Chain Reaction; Proto-Oncogene Proteins p21(ras); Renal Insufficiency, Chronic

2019
Nilotinib ameliorates folic acid-induced acute kidney injury through modulation of TWEAK and HSP-70 pathways.
    Toxicology, 2019, 11-01, Volume: 427

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Cytokine TWEAK; Cytokines; Folic Acid; HSP70 Heat-Shock Proteins; Kidney; Male; Mice, Inbred BALB C; Nitric Oxide; Pyrimidines; Signal Transduction

2019
Extra-Large Gα Protein (XLαs) Deficiency Causes Severe Adenine-Induced Renal Injury with Massive FGF23 Elevation.
    Endocrinology, 2020, Jan-01, Volume: 161, Issue:1

    Topics: Acute Kidney Injury; Adenine; Animals; Blood Urea Nitrogen; Bone and Bones; Diet; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Folic Acid; GTP-Binding Protein alpha Subunits, Gs; Male; Mice, Knockout; Renal Insufficiency, Chronic; Sex Factors; Vitamin B Complex

2020
Effective Nephroprotection Against Acute Kidney Injury with a Star-Shaped Polyglutamate-Curcuminoid Conjugate.
    Scientific reports, 2020, 02-06, Volume: 10, Issue:1

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Line; Diarylheptanoids; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Folic Acid; Glucuronidase; Humans; Kidney Tubules; Klotho Proteins; Mice; Molecular Conformation; Necrosis; NF-kappa B; Polyglutamic Acid; Protective Agents; Signal Transduction; Structure-Activity Relationship; Transcription, Genetic

2020
Chronic impairment of mitochondrial bioenergetics and β-oxidation promotes experimental AKI-to-CKD transition induced by folic acid.
    Free radical biology & medicine, 2020, Volume: 154

    Topics: Acute Kidney Injury; Disease Progression; Energy Metabolism; Folic Acid; Humans; Mitochondria; Oxidation-Reduction; Renal Insufficiency, Chronic

2020
The potential protective role of folic acid against acetaminophen-induced hepatotoxicity and nephrotoxicity in rats.
    Experimental animals, 2021, Feb-06, Volume: 70, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Folic Acid; Free Radical Scavengers; Oxidative Stress; Rats, Sprague-Dawley

2021
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
    British journal of pharmacology, 2021, Volume: 178, Issue:2

    Topics: Acute Kidney Injury; Animals; Circadian Rhythm; Ferroptosis; Folic Acid; Mice; Nuclear Receptor Subfamily 1, Group D, Member 1

2021
Nicorandil mitigates folic acid-induced nephrotoxicity in mice: Role of iNOS and eNOS.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:4

    Topics: Acute Kidney Injury; Animals; Dose-Response Relationship, Drug; Folic Acid; Male; Mice; Nicorandil; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III

2021
Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.
    British journal of pharmacology, 2021, Volume: 178, Issue:5

    Topics: Acute Kidney Injury; Animals; Aporphines; Ferroptosis; Folic Acid; HEK293 Cells; Humans; Mice

2021
Orphan nuclear receptor ERR-γ regulates hepatic FGF23 production in acute kidney injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 04-20, Volume: 118, Issue:16

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Fibroblast Growth Factor-23; Folic Acid; Interleukin-6; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Receptors, Estrogen; Transcriptional Activation

2021
Genetic and pharmacological inhibition of fatty acid-binding protein 4 alleviated inflammation and early fibrosis after toxin induced kidney injury.
    International immunopharmacology, 2021, Volume: 96

    Topics: Acute Kidney Injury; Animals; Aristolochic Acids; Biphenyl Compounds; Carcinogens; Disease Models, Animal; Fatty Acid-Binding Proteins; Fibrosis; Folic Acid; Hematinics; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyrazoles; RNA, Small Interfering

2021
TWEAK and RIPK1 mediate a second wave of cell death during AKI.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 04-17, Volume: 115, Issue:16

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Line; Cellular Microenvironment; Cytokine TWEAK; Enzyme Activation; Female; Folic Acid; Imidazoles; Indoles; Inflammation; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; Necrosis; Receptor-Interacting Protein Serine-Threonine Kinases; TWEAK Receptor

2018
Treatment dose and the elimination rates of electrolytes, vitamins, and trace elements during continuous veno-venous hemodialysis (CVVHD).
    International urology and nephrology, 2018, Volume: 50, Issue:6

    Topics: Acute Kidney Injury; Aged; Anticoagulants; Calcium; Citric Acid; Dialysis Solutions; Electrolytes; Female; Folic Acid; Humans; Magnesium; Male; Middle Aged; Phosphates; Prospective Studies; Renal Dialysis; Trace Elements; Vitamin B 12; Vitamins; Zinc

2018
Interleukin-6 contributes to the increase in fibroblast growth factor 23 expression in acute and chronic kidney disease.
    Kidney international, 2018, Volume: 94, Issue:2

    Topics: Acute Kidney Injury; Adenine; Animals; Bone and Bones; Dexamethasone; Disease Models, Animal; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Folic Acid; Glucocorticoids; Humans; Interleukin-6; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Promoter Regions, Genetic; Receptors, Interleukin-6; Recombinant Fusion Proteins; Renal Insufficiency, Chronic; RNA, Messenger; STAT3 Transcription Factor; Transcription, Genetic

2018
CCL20 blockade increases the severity of nephrotoxic folic acid-induced acute kidney injury.
    The Journal of pathology, 2018, Volume: 246, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Animals; Antibodies, Neutralizing; Case-Control Studies; Cell Line; Chemokine CCL20; Chemotaxis, Leukocyte; Disease Models, Animal; Female; Fibrosis; Folic Acid; Gene Expression Profiling; Humans; Immunity, Innate; Kidney Tubules; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Receptors, CCR6; Severity of Illness Index; Signal Transduction; Systems Biology; T-Lymphocytes, Regulatory; Th17 Cells; Young Adult

2018
Multiparametric MRI detects longitudinal evolution of folic acid-induced nephropathy in mice.
    American journal of physiology. Renal physiology, 2018, 11-01, Volume: 315, Issue:5

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Disease Progression; Fibrosis; Folic Acid; Glomerular Filtration Rate; Kidney; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Necrosis; Organ Size; Predictive Value of Tests; Renal Circulation; Time Factors

2018
Aristolochic acid I determine the phenotype and activation of macrophages in acute and chronic kidney disease.
    Scientific reports, 2018, 08-15, Volume: 8, Issue:1

    Topics: Acute Kidney Injury; Animals; Aristolochic Acids; Cisplatin; Disease Models, Animal; Female; Fibrosis; Folic Acid; Kidney; Kidney Diseases; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Phenotype; Renal Insufficiency, Chronic

2018
Targeting enhancer of zeste homolog 2 protects against acute kidney injury.
    Cell death & disease, 2018, 10-19, Volume: 9, Issue:11

    Topics: Acute Kidney Injury; Adenosine; Adherens Junctions; Animals; Apoptosis; Cadherins; Cells, Cultured; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Epithelial Cells; Folic Acid; Hydrogen Peroxide; Jumonji Domain-Containing Histone Demethylases; Kidney; Kidney Tubules; Lipocalin-2; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Phosphatidylethanolamine Binding Protein; Phosphorylation; Proto-Oncogene Proteins c-raf; Reperfusion Injury; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Zonula Occludens-1 Protein

2018
Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid.
    Free radical biology & medicine, 2019, Volume: 130

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Disease Models, Animal; Energy Metabolism; Folic Acid; Glutathione; Humans; Mitochondria; Mitochondrial Dynamics; Oxidative Stress; Protein Processing, Post-Translational; Rats

2019
Matrix metalloproteinase-7 protects against acute kidney injury by priming renal tubules for survival and regeneration.
    Kidney international, 2019, Volume: 95, Issue:5

    Topics: Acute Kidney Injury; Animals; Apoptosis; beta Catenin; Cell Proliferation; Cell Survival; Disease Models, Animal; Epithelial Cells; Fas Ligand Protein; Folic Acid; Humans; Kidney Tubules; Matrix Metalloproteinase 7; Mice; Mice, Knockout; Proteolysis; Regeneration; Reperfusion Injury; Signal Transduction

2019
PGC-1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI.
    The Journal of pathology, 2019, Volume: 249, Issue:1

    Topics: Acute Kidney Injury; Animals; Cell Death; Cell Line; Cell Proliferation; Cytokines; Disease Models, Animal; Female; Folic Acid; Humans; Inflammation Mediators; Kidney; Lipocalin-2; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Nephritis, Interstitial; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Severity of Illness Index; Signal Transduction

2019
GSK3β-mediated Keap1-independent regulation of Nrf2 antioxidant response: A molecular rheostat of acute kidney injury to chronic kidney disease transition.
    Redox biology, 2019, Volume: 26

    Topics: Acute Kidney Injury; Animals; Antioxidants; Biomarkers; Biopsy; Disease Models, Animal; Disease Progression; Disease Susceptibility; Folic Acid; Glycogen Synthase Kinase 3 beta; Immunohistochemistry; Kelch-Like ECH-Associated Protein 1; Lithium; Male; Mice; NF-E2-Related Factor 2; Renal Insufficiency, Chronic

2019
The anti-oxidant effects are not the main mechanism for glutamine's protective effects on acute kidney injury in mice.
    European journal of pharmacology, 2013, Apr-05, Volume: 705, Issue:1-3

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Chemokine CXCL1; Chemokine CXCL2; Folic Acid; Glutamine; Glutathione; HSP70 Heat-Shock Proteins; Lipocalin-2; Lipocalins; Male; Malondialdehyde; Mice; Neutrophil Infiltration; Oncogene Proteins; Peroxidase; Protective Agents; Protein Carbonylation; Tumor Necrosis Factor-alpha

2013
Plasma FGF23 levels increase rapidly after acute kidney injury.
    Kidney international, 2013, Volume: 84, Issue:4

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Animals; Biomarkers; Case-Control Studies; Cohort Studies; Disease Models, Animal; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Folic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Parathyroid Hormone; Phosphates; Prospective Studies; Signal Transduction; Time Factors; Vitamin D

2013
cGMP-selective phosphodiesterase inhibitors stimulate mitochondrial biogenesis and promote recovery from acute kidney injury.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 347, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acute Kidney Injury; Adenosine Triphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Gene Expression; Hematinics; Kidney Cortex; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxygen Consumption; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; Rabbits; Real-Time Polymerase Chain Reaction; Sildenafil Citrate; Sulfones; Uncoupling Agents

2013
Endothelial sirtuin 1 deficiency perpetrates nephrosclerosis through downregulation of matrix metalloproteinase-14: relevance to fibrosis of vascular senescence.
    Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:2

    Topics: Acute Kidney Injury; Animals; Cellular Senescence; Concanavalin A; Down-Regulation; Endothelium, Vascular; Exons; Extracellular Matrix; Fibrosis; Folic Acid; Gene Expression Regulation, Enzymologic; Human Umbilical Vein Endothelial Cells; Kidney; Kidney Failure, Chronic; Male; Matrix Metalloproteinase 14; Mice; Mice, Mutant Strains; Mice, Transgenic; Neovascularization, Physiologic; Nephrosclerosis; Regeneration; Sirtuin 1; Vasodilation

2014
Suppressed mitochondrial biogenesis in folic acid-induced acute kidney injury and early fibrosis.
    Toxicology letters, 2014, Jan-30, Volume: 224, Issue:3

    Topics: Actins; Acute Kidney Injury; Animals; Blotting, Western; Collagen; Creatinine; DNA; Electron Transport Complex IV; Fibrosis; Folic Acid; Glycosuria; Hematinics; Homeostasis; Male; Mice; Mitochondria; Mitochondrial Diseases; RNA, Messenger

2014
Class I HDAC activity is required for renal protection and regeneration after acute kidney injury.
    American journal of physiology. Renal physiology, 2014, Aug-01, Volume: 307, Issue:3

    Topics: Acute Kidney Injury; Animals; Cell Proliferation; Cell Survival; Disease Models, Animal; Epithelial Cells; ErbB Receptors; Folic Acid; Histone Deacetylases; Isoenzymes; Kidney; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; Regeneration; Rhabdomyolysis; STAT3 Transcription Factor

2014
Acute kidney injury and progression of renal failure after fetal programming in the offspring of diabetic rats.
    Pediatric research, 2015, Volume: 77, Issue:3

    Topics: Acute Kidney Injury; Animals; Creatinine; Diabetes Complications; Epithelial-Mesenchymal Transition; Fetal Development; Folic Acid; Gene Expression Regulation; Immunohistochemistry; Kidney Function Tests; Polymerase Chain Reaction; Rats; Renal Insufficiency; Urea

2015
The restrained expression of NF-kB in renal tissue ameliorates folic acid induced acute kidney injury in mice.
    PloS one, 2015, Volume: 10, Issue:1

    Topics: Acute Kidney Injury; Animals; Antioxidants; Folic Acid; Gene Expression; Immunohistochemistry; Kidney; Kidney Cortex; Kidney Function Tests; Male; Mice, Inbred BALB C; Microscopy, Electron, Transmission; NF-kappa B; NF-kappa B p52 Subunit; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; Thiocarbamates; Transcription Factor RelA; Tumor Suppressor Protein p53

2015
Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage.
    Journal of the American Society of Nephrology : JASN, 2015, Volume: 26, Issue:12

    Topics: Acute Kidney Injury; Adult; Allografts; Amidohydrolases; Animals; Arginine; Collagen Type I; Collagen Type I, alpha 1 Chain; Female; Folic Acid; Gene Expression; Glomerular Filtration Rate; Humans; Kidney Transplantation; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Nitric Oxide; RNA, Messenger; Transaminases; Ureteral Obstruction; Uromodulin

2015
The fibroblast growth factor receptor mediates the increased FGF23 expression in acute and chronic uremia.
    American journal of physiology. Renal physiology, 2016, Feb-01, Volume: 310, Issue:3

    Topics: Acute Kidney Injury; Adenine; Animals; Chronic Disease; Disease Models, Animal; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Folic Acid; Male; Mice, Inbred C57BL; Osteocytes; Parathyroid Hormone; Phosphorus, Dietary; Pyrimidines; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 1; RNA, Messenger; Skull; Up-Regulation; Uremia

2016
MRL/MpJ mice show unique pathological features after experimental kidney injury.
    Histology and histopathology, 2016, Volume: 31, Issue:2

    Topics: Acute Kidney Injury; Animals; Calcinosis; Disease Models, Animal; Fibrosis; Folic Acid; Kidney; Kidney Diseases; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenotype; Transforming Growth Factor beta1; Wound Healing

2016
Adipose Tissue-Derived Stem Cells Reduce Acute and Chronic Kidney Damage in Mice.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Acute Kidney Injury; Adipose Tissue; Animals; Cells, Cultured; Chronic Disease; Disease Models, Animal; Folic Acid; Kidney; Male; Mice; Stem Cell Transplantation; Stem Cells; Urea

2015
Application of small RNA sequencing to identify microRNAs in acute kidney injury and fibrosis.
    Toxicology and applied pharmacology, 2016, Dec-01, Volume: 312

    Topics: Acute Kidney Injury; Animals; Fibrosis; Folic Acid; In Situ Hybridization; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred BALB C; MicroRNAs; RNA

2016
Tanshinone IIA Attenuates Renal Fibrosis after Acute Kidney Injury in a Mouse Model through Inhibition of Fibrocytes Recruitment.
    BioMed research international, 2015, Volume: 2015

    Topics: Abietanes; Acute Kidney Injury; Animals; Fibrosis; Folic Acid; Kidney; Mice; Mice, Inbred C57BL

2015
Soluble Fn14 Is Detected and Elevated in Mouse and Human Kidney Disease.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Acute Kidney Injury; Adult; Animals; Chromatography, Liquid; Disease Models, Animal; Folic Acid; Humans; Kidney; Kidney Diseases; Lupus Nephritis; Male; Mice; Receptors, Tumor Necrosis Factor; Reperfusion Injury; Solubility; Tandem Mass Spectrometry; TWEAK Receptor; Up-Regulation

2016
Tanshinone IIA Protects Against Folic Acid-Induced Acute Kidney Injury.
    The American journal of Chinese medicine, 2016, Volume: 44, Issue:4

    Topics: Abietanes; Acute Kidney Injury; Animals; Drugs, Chinese Herbal; Folic Acid; Humans; Kidney; Lipocalin-2; Male; Mice; Mice, Inbred C57BL; Phytotherapy; Proliferating Cell Nuclear Antigen; Protective Agents; Salvia miltiorrhiza

2016
Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury.
    Scientific reports, 2016, 06-07, Volume: 6

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cathepsin D; Cell Line; Disease Models, Animal; Folic Acid; Humans; Kidney Function Tests; Kidney Tubules; Male; Mice; Nephrosis; Pepstatins; Reperfusion Injury; Up-Regulation

2016
Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid-Induced AKI.
    Journal of the American Society of Nephrology : JASN, 2017, Volume: 28, Issue:1

    Topics: Acute Kidney Injury; Animals; Cell Death; Folic Acid; Iron; Mice; Mice, Inbred C57BL; Necrosis

2017
Rescue therapy with Tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease via targeting GSK3β.
    Scientific reports, 2016, 11-18, Volume: 6

    Topics: Abietanes; Acute Kidney Injury; Animals; Folic Acid; Glycogen Synthase Kinase 3 beta; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Macrophages; MAP Kinase Signaling System; Mice

2016
PHF14: an innate inhibitor against the progression of renal fibrosis following folic acid-induced kidney injury.
    Scientific reports, 2017, 01-03, Volume: 7

    Topics: Actins; Acute Kidney Injury; Animals; Cell Line; Collagen Type I; Fibroblasts; Fibrosis; Folic Acid; Mice; Mice, Inbred C57BL; Platelet-Derived Growth Factor; Rats; Receptor, Platelet-Derived Growth Factor alpha; Smad3 Protein; Transcription Factors; Transforming Growth Factor beta; Up-Regulation

2017
Gremlin1 plays a key role in kidney development and renal fibrosis.
    American journal of physiology. Renal physiology, 2017, 06-01, Volume: 312, Issue:6

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Female; Fibrosis; Folic Acid; Gene Expression Regulation; Genetic Predisposition to Disease; Intercellular Signaling Peptides and Proteins; Kidney Tubules; Mice, Inbred C57BL; Mice, Knockout; Organogenesis; Phenotype; Signal Transduction; Time Factors; Urogenital Abnormalities

2017
Challenges of targeting vascular stability in acute kidney injury.
    Kidney international, 2008, Volume: 74, Issue:3

    Topics: Acute Kidney Injury; Angiopoietin-1; Animals; Endothelium, Vascular; Fibrosis; Folic Acid; Humans; Neovascularization, Physiologic; Renal Circulation

2008
Decreased urinary secretion of belotecan in folic acid-induced acute renal failure rats due to down-regulation of Oat1 and Bcrp.
    Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:10

    Topics: Acridines; Acute Kidney Injury; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Camptothecin; Down-Regulation; Folic Acid; Glomerular Filtration Rate; Indicators and Reagents; Kidney; Male; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Verapamil; Vitamin B Complex

2009
Folic acid induces acute renal failure (ARF) by enhancing renal prooxidant state.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:3

    Topics: Acute Kidney Injury; Animals; Folic Acid; Male; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Oxidative Stress; Vitamin B Complex

2012
Modified citrus pectin reduces galectin-3 expression and disease severity in experimental acute kidney injury.
    PloS one, 2011, Apr-08, Volume: 6, Issue:4

    Topics: Acute Kidney Injury; Animals; Apoptosis; Body Weight; Cell Proliferation; Citrus; Cytokines; Fibrosis; Folic Acid; Galectin 3; Kidney Function Tests; Mice; Mice, Inbred C57BL; Organ Size; Pectins; Phytotherapy; Up-Regulation

2011
N-acetylcysteine is effective for prevention but not for treatment of folic acid-induced acute kidney injury in mice.
    Critical care medicine, 2011, Volume: 39, Issue:11

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Animals, Outbred Strains; Creatinine; Cystatin C; Folic Acid; Glutathione; Kidney Function Tests; Male; Mice; Survival Analysis

2011
Differential effects of kidney-lung cross-talk during acute kidney injury and bacterial pneumonia.
    Kidney international, 2011, Volume: 80, Issue:6

    Topics: Acute Kidney Injury; Animals; Bacterial Load; Blood Platelets; Disease Models, Animal; Folic Acid; Kidney; Lung; Mice; Mice, Inbred C57BL; Models, Biological; Neutrophils; Organ Specificity; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections

2011
One dose of cyclosporine A is protective at initiation of folic acid-induced acute kidney injury in mice.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:8

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Blood Urea Nitrogen; Creatinine; Cyclosporine; Cytokine TWEAK; Disease Models, Animal; Fibrosis; Folic Acid; Immunosuppressive Agents; Interleukin-6; Lipocalin-2; Lipocalins; Male; Mice; NF-kappa B; Oncogene Proteins; Tumor Necrosis Factors

2012
Tubule-specific ablation of endogenous β-catenin aggravates acute kidney injury in mice.
    Kidney international, 2012, Volume: 82, Issue:5

    Topics: Acute Kidney Injury; Adherens Junctions; Animals; Apoptosis; bcl-2-Associated X Protein; beta Catenin; Cadherins; Cell Line; Creatinine; Disease Models, Animal; Epithelial Cells; Folic Acid; gamma Catenin; Genotype; Humans; Inhibitor of Apoptosis Proteins; Kidney Tubules; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Phosphorylation; Proto-Oncogene Proteins c-akt; Reperfusion Injury; Repressor Proteins; Survivin; Time Factors; Transfection; Tumor Suppressor Protein p53; Wnt1 Protein

2012
Renoprotective effect of human umbilical cord-derived mesenchymal stem cells in immunodeficient mice suffering from acute kidney injury.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Acute Kidney Injury; Animals; Antigens, CD; Apoptosis; Blood Urea Nitrogen; Caspases; Cell Differentiation; Cell Proliferation; Creatinine; Cytokines; Cytoprotection; Folic Acid; Humans; Inflammation Mediators; Insulin-Like Growth Factor I; Kidney Tubules; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred NOD; Mice, SCID; Tissue Array Analysis; Umbilical Cord; Wharton Jelly

2012
EGFR activity is required for renal tubular cell dedifferentiation and proliferation in a murine model of folic acid-induced acute kidney injury.
    American journal of physiology. Renal physiology, 2013, Feb-15, Volume: 304, Issue:4

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Dedifferentiation; Cell Proliferation; Creatinine; ErbB Receptors; Folic Acid; Gefitinib; Kidney Tubules; Mice; Mice, Inbred C57BL; PAX2 Transcription Factor; Phosphatidylinositol 3-Kinases; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction

2013
Parathyroid hormone-related protein protects renal tubuloepithelial cells from apoptosis by activating transcription factor Runx2.
    Kidney international, 2013, Volume: 83, Issue:5

    Topics: Active Transport, Cell Nucleus; Acute Kidney Injury; Animals; Apoptosis; Cell Line; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Epithelial Cells; Folic Acid; Humans; Kidney Failure, Chronic; Kidney Tubules, Proximal; Mice; Mice, Transgenic; Osteopontin; Parathyroid Hormone-Related Protein; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Signal Transduction; Time Factors; Transfection

2013
Expression of Smac/Diablo in tubular epithelial cells and during acute renal failure.
    Kidney international. Supplement, 2003, Issue:86

    Topics: Acute Kidney Injury; Animals; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Cells, Cultured; Epithelial Cells; Folic Acid; Kidney Tubules; Mice; Mice, Inbred BALB C; Mitochondrial Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha

2003
[INTESTINAL ABSORPTION OF TRITIUM-LABELLED FOLIC ACID (THE TRIFA TEST)].
    Nordisk medicin, 1964, Apr-30, Volume: 71

    Topics: Absorption; Acute Kidney Injury; Anemia; Anemia, Macrocytic; Celiac Disease; Diagnosis, Differential; Folic Acid; Humans; Injections, Intramuscular; Intestinal Absorption; Intestines; Renal Insufficiency; Tritium; Urine

1964
Pharmacokinetics of tolbutamide after oral administration in rabbits with folate-induced renal failure.
    Research communications in molecular pathology and pharmacology, 2002, Volume: 111, Issue:5-6

    Topics: Acute Kidney Injury; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Folic Acid; Hypoglycemic Agents; Liver; Rabbits; Regression Analysis; Spectrophotometry, Ultraviolet; Tolbutamide

2002
Rare incorporation of bone marrow-derived cells into kidney after folic acid-induced injury.
    Stem cells (Dayton, Ohio), 2005, Volume: 23, Issue:1

    Topics: Acute Kidney Injury; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Differentiation; Disease Models, Animal; Female; Folic Acid; Immunohistochemistry; In Situ Hybridization, Fluorescence; In Vitro Techniques; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Species Specificity

2005
Role of the renin-angiotensin system on the parathyroid hormone-related protein overexpression induced by nephrotoxic acute renal failure in the rat.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:4

    Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Line; Enalapril; Folic Acid; Gentamicins; Kidney; Kidney Tubules; Losartan; Male; Parathyroid Hormone-Related Protein; Quinapril; Rats; Rats, Wistar; Receptor, Parathyroid Hormone, Type 1; Renin-Angiotensin System; Tetrahydroisoquinolines

2005
Calcium-binding proteins annexin A2 and S100A6 are sensors of tubular injury and recovery in acute renal failure.
    Kidney international, 2005, Volume: 68, Issue:6

    Topics: Acute Kidney Injury; Animals; Annexin A2; Biomarkers; Calcium-Binding Proteins; Female; Folic Acid; Kidney Tubules; Mice; Mice, Inbred C57BL; Proliferating Cell Nuclear Antigen; Recovery of Function; Reperfusion Injury; Uranyl Nitrate; Vitamin B Complex

2005
Blocking tumor necrosis factor-alpha inhibits folic acid-induced acute renal failure.
    Experimental and molecular pathology, 2006, Volume: 81, Issue:3

    Topics: Acute Kidney Injury; Animals; Antibodies; Apoptosis; bcl-X Protein; Blood Urea Nitrogen; Epithelial Cells; Folic Acid; Kidney Tubules, Proximal; Mice; Necrosis; Neutralization Tests; Tumor Necrosis Factor-alpha

2006
Cytokine cooperation in renal tubular cell injury: the role of TWEAK.
    Kidney international, 2006, Volume: 70, Issue:10

    Topics: Acute Kidney Injury; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspases; Cell Line; Cysteine Proteinase Inhibitors; Cytokine TWEAK; Cytokines; Endoplasmic Reticulum; Folic Acid; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Interferon-gamma; Kidney Tubules, Proximal; Mice; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha; Tumor Necrosis Factors; TWEAK Receptor

2006
Protective role of the inhibitor of apoptosis protein, survivin, in toxin-induced acute renal failure.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:2

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cisplatin; Disease Susceptibility; Folic Acid; Gene Expression Regulation; Genetic Therapy; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Knockout; Microtubule-Associated Proteins; Necrosis; Repressor Proteins; Survivin

2008
Carboxypeptidase G2 rescue in a 79 year-old patient with cranial lymphoma after high-dose methotrexate induced acute renal failure.
    Leukemia & lymphoma, 1999, Volume: 35, Issue:5-6

    Topics: Acute Kidney Injury; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bacterial Proteins; Carmustine; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Diuretics; Doxorubicin; Ethmoid Sinus; Female; Fluid Therapy; Folic Acid; Furosemide; gamma-Glutamyl Hydrolase; Humans; Leucovorin; Lymphoma, B-Cell; Lymphoma, Large-Cell, Immunoblastic; Methotrexate; Paranasal Sinus Neoplasms; Prednisone; Procarbazine; Remission Induction; Vincristine

1999
Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure.
    Kidney international, 2000, Volume: 57, Issue:3

    Topics: Acute Kidney Injury; Animals; Apoptosis; bcl-X Protein; Cell Death; Cells, Cultured; Culture Media, Serum-Free; Epithelial Cells; Folic Acid; Gene Expression; Kidney Tubules; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Stress, Physiological; Tumor Necrosis Factor-alpha

2000
DNA degradation in the kidney of folic acid-treated guinea pigs.
    Cytobios, 2000, Volume: 102, Issue:400

    Topics: Acute Kidney Injury; Aminoisobutyric Acids; Animals; Chromatography, Thin Layer; Creatinine; Diuretics; DNA; Epithelial Cells; Folic Acid; Furosemide; Guinea Pigs; Hematinics; Injections, Intramuscular; Injections, Intraperitoneal; Kidney; Male; Necrosis; Thymine; Urea

2000
Up-regulation of galectin-3 in acute renal failure of the rat.
    The American journal of pathology, 2000, Volume: 157, Issue:3

    Topics: Acute Kidney Injury; Animals; Antigens, Differentiation; Creatinine; Folic Acid; Galectin 3; Immunoenzyme Techniques; Kidney; Lectins; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Up-Regulation

2000
Reversible acute renal failure with prolonged oliguria and gross hematuria in a case of paroxysmal nocturnal hemoglobinuria.
    Scandinavian journal of urology and nephrology, 2000, Volume: 34, Issue:4

    Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents; Blood Transfusion; Folic Acid; Hematuria; Hemoglobinuria, Paroxysmal; Humans; Iron; Male; Oliguria; Prednisolone; Renal Dialysis

2000
Up-regulation of parathyroid hormone-related protein in folic acid-induced acute renal failure.
    Kidney international, 2001, Volume: 60, Issue:3

    Topics: Acute Kidney Injury; Angiotensin II; Animals; Cell Division; Disease Models, Animal; Endothelin-1; Endothelins; Epithelial Cells; Folic Acid; Immunohistochemistry; Kidney Cortex; Kidney Tubules; Male; Parathyroid Hormone-Related Protein; Peptidyl-Dipeptidase A; Protein Precursors; Proteins; Rats; Rats, Wistar; Regeneration; Up-Regulation

2001
Pharmacokinetics of diltiazem and its major metabolite, deacetyidiltiazem after oral administration of diltiazem in mild and medium folate-induced renal failure rabbits.
    Archives of pharmacal research, 2001, Volume: 24, Issue:4

    Topics: Acute Kidney Injury; Animals; Area Under Curve; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Folic Acid; Male; Rabbits

2001
Acute tubular necrosis. An experimental model detailing the biochemical events accompanying renal injury and recovery.
    Investigative urology, 1976, Volume: 13, Issue:4

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Body Weight; Disease Models, Animal; DNA; Folic Acid; Hydrogen-Ion Concentration; Kidney; Kidney Tubular Necrosis, Acute; Male; Mice; Organ Size; Polyribosomes; Proteins; RNA; Solubility

1976
Acute renal failure in the folate-treated rat: early metabolic changes in various structures of the nephron.
    Kidney international. Supplement, 1976, Volume: 6

    Topics: Acute Kidney Injury; Adenosine Triphosphatases; Animals; Biological Transport, Active; Blood Glucose; Folic Acid; Glycolysis; Kidney; Male; Nephrons; Oxidative Phosphorylation; Phosphofructokinase-1; Potassium; Pyruvate Kinase; Rats; Sodium

1976
Intra- and extrarenal vascular changes in the acute renal failure of the rat caused by high-dose folic acid injection.
    Virchows Archiv. A, Pathological anatomy and histology, 1977, Oct-27, Volume: 376, Issue:1

    Topics: Acute Kidney Injury; Animals; Blood Vessels; Brain; Coronary Vessels; Edema; Fibrin; Folic Acid; Kidney; Kidney Tubules; Liver; Male; Mesentery; Muscle, Smooth; Necrosis; Pancreas; Rats; Time Factors

1977
An evaluation of the role of tubular obstruction in folic acid-induced acute renal failure in the rat. A micropuncture study.
    Nephron, 1978, Volume: 22, Issue:1-3

    Topics: Acute Kidney Injury; Animals; Bicarbonates; Folic Acid; Furosemide; Glomerular Filtration Rate; Kidney Medulla; Kidney Tubules; Kidney Tubules, Proximal; Oliguria; Pressure; Punctures; Rats

1978
[Cell proliferation in renal tubular and kidney pelvis epithelium of the rat following folic acid application].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1978, Volume: 62

    Topics: Acute Kidney Injury; Animals; Epithelium; Folic Acid; Kidney Pelvis; Kidney Tubular Necrosis, Acute; Kidney Tubules; Male; Mitotic Index; Rats; Regeneration

1978
Morphologic demonstration of tubular obstruction in acute renal failure.
    The American journal of pathology, 1977, Volume: 87, Issue:2

    Topics: Acute Kidney Injury; Animals; Anuria; Ferrocyanides; Folic Acid; Injections, Intravenous; Kidney Tubules; Methemoglobin; Oliguria; Rabbits

1977
Reduction of folic acid-induced acute tubular injury by diuresis: an experimental model.
    Experimental and molecular pathology, 1976, Volume: 25, Issue:1

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Body Weight; Disease Models, Animal; Diuresis; DNA; Folic Acid; Furosemide; Kidney; Kidney Tubular Necrosis, Acute; Male; Mice; Organ Size; RNA

1976
Folic acid-induced acute renal failure in the the rat: morphological studies.
    Kidney international. Supplement, 1976, Volume: 6

    Topics: Acute Kidney Injury; Animals; Dilatation, Pathologic; Folic Acid; Kidney; Kidney Medulla; Kidney Tubular Necrosis, Acute; Kidney Tubules; Male; Nephrocalcinosis; Oliguria; Organ Size; Rats; Time Factors

1976
Folic acid deficiency during intensive therapy.
    British medical journal, 1975, Oct-18, Volume: 4, Issue:5989

    Topics: Acute Kidney Injury; Adult; Bone Marrow Diseases; Critical Care; Folic Acid; Folic Acid Deficiency; Humans; Male; Megakaryocytes; Megaloblasts; Renal Dialysis; Wounds and Injuries

1975
Sequential protooncogene expression in regenerating kidney following acute renal injury.
    The Journal of biological chemistry, 1989, May-15, Volume: 264, Issue:14

    Topics: Actins; Acute Kidney Injury; Animals; Cell Division; DNA; Folic Acid; gamma-Glutamyltransferase; Gene Expression Regulation; Histones; Kidney; Mercuric Chloride; Mice; Nucleic Acid Hybridization; Ornithine-Oxo-Acid Transaminase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes; Regeneration; RNA, Messenger

1989
Phase II study of the antifolate N10-propargyl-5,8-dideazafolic acid (CB 3717) in advanced breast cancer.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Drug Evaluation; Female; Folic Acid; Folic Acid Antagonists; Humans; Middle Aged; Quinazolines; Thymidylate Synthase

1988
[Proceedings: Renin secretion and juxtaglomerular apparatus in folic-acid-induced kidney failure in the rat].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1973, Volume: 57

    Topics: Acute Kidney Injury; Animals; Folic Acid; Juxtaglomerular Apparatus; Male; Rats; Renin

1973
Peritoneal dialysis in acute renal failure following malaria.
    Lancet (London, England), 1967, Aug-26, Volume: 2, Issue:7513

    Topics: Acute Kidney Injury; Adult; Bicarbonates; Chloroquine; Folic Acid; Humans; Hydrocortisone; Malaria; Male; Penicillins; Peritoneal Dialysis; Sodium Chloride

1967
Acute renal failure after folate: NaK ATPase in isolated rat renal tubule. Ultramicrochemical and clinical studies.
    European journal of clinical investigation, 1973, Volume: 3, Issue:3

    Topics: Acute Kidney Injury; Adenosine Triphosphatases; Animals; Folic Acid; Kidney Tubules; Kidney Tubules, Distal; Kidney Tubules, Proximal; Loop of Henle; Male; Nephrons; Osmolar Concentration; Potassium; Rats; Sodium; Time Factors; Urea; Urine

1973
Renal diseases.
    Clinics in haematology, 1972, Volume: 1, Issue:3

    Topics: Acute Kidney Injury; Adult; Anemia; Animals; Blood Platelets; Disseminated Intravascular Coagulation; Erythropoietin; Female; Folic Acid; Hemolysis; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Polycythemia; Pre-Eclampsia; Pregnancy; Rabbits; Renal Dialysis; Transplantation, Homologous

1972
Acute renal failure in the rat after folate intoxication: diagnostic value of lactate dehydrogenase and alkaline phosphatase measurements in serum and urine.
    Clinical nephrology, 1974, Volume: 2, Issue:3

    Topics: Acute Kidney Injury; Alkaline Phosphatase; Animals; Bicarbonates; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Folic Acid; Hydrogen-Ion Concentration; Isoenzymes; L-Lactate Dehydrogenase; Male; Rats

1974
Plasma renin activity in folic acid induced acute renal failure.
    Klinische Wochenschrift, 1972, Aug-15, Volume: 50, Issue:16

    Topics: Acute Kidney Injury; Animals; Creatinine; Folic Acid; Glomerular Filtration Rate; Hemorrhage; Kidney Tubules; Male; Rats; Renin; Time Factors

1972
[Resistance of dichromate induced-renal lesions after injection of folic acid].
    Virchows Archiv. A, Pathology. Pathologische Anatomie, 1971, Volume: 353, Issue:3

    Topics: Acute Kidney Injury; Animals; Body Weight; Chromates; Diuresis; Folic Acid; Hypertrophy; Injections, Subcutaneous; Kidney Glomerulus; Kidney Tubules; Male; Natriuresis; Nucleic Acids; Organ Size; Periodicity; Potassium; Rats

1971
[Acute renal failure after pteridine administration].
    Klinische Wochenschrift, 1970, Oct-15, Volume: 48, Issue:20

    Topics: Acute Kidney Injury; Animals; Anuria; Chlorothiazide; Diuretics; Folic Acid; Furosemide; Glomerular Filtration Rate; Kidney Function Tests; Kidney Tubules; Male; Pteridines; Pyrazines; Rats; Water-Electrolyte Balance; Xanthopterin

1970
Serum folate and vitamin B12 levels in acute and chronic renal disease. Effect of peritoneal dialysis.
    British medical journal, 1969, Apr-05, Volume: 2, Issue:5648

    Topics: Acute Kidney Injury; Adolescent; Adult; Female; Folic Acid; Humans; Kidney Failure, Chronic; Leukocytes; Male; Middle Aged; Pancreatitis; Peritoneal Dialysis; Urea; Vitamin B 12

1969