Page last updated: 2024-08-17

folic acid and Abnormalities, Drug-Induced

folic acid has been researched along with Abnormalities, Drug-Induced in 109 studies

Research

Studies (109)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (26.61)	18.7374
1990's	15 (13.76)	18.2507
2000's	31 (28.44)	29.6817
2010's	30 (27.52)	24.3611
2020's	4 (3.67)	2.80

Authors

Authors	Studies
Błaszczyk, B; Czuczwar, SJ; Miziak, B; Pluta, R	1
Cadena, MRS; Cadena, PG; Marrs, JA; Sarmah, S	1
Eadie, MJ; Graham, JE; Hitchcock, AA; Lander, CM; O'Brien, TJ; Perucca, P; Vajda, FJE	1
Obara, T	1
Bomba-Opoń, D; Jakiel, G; Jędrzejczak, J; Kwaśniewska, A; Mirowska-Guzel, D	1
Akhtar, MS; Tahir, M	1
Frieauff, E; Rehn, M; Stüber, T; Wiedemann, K	1
Arluck, JC; Mayhew, AC	1
Koren, G; Ornoy, A; Yanai, J	1
Gandelman-Marton, R; Neufeld, M	1
Ahmed, R; Apen, K; Endean, C	1
Fathe, K; Finnell, RH; Palacios, A	1
Fu, YX; Gan, LQ; He, XM; Liu, CP; Liu, Y; Qiu, L; Tian, XF; Wei, GH; Xiao, J; Yuan, XG	1
He, W; Li, C; Lu, S; Meng, T; Shi, B	1
Ban, L; Doyle, P; Fiaschi, L; Fleming, KM; Hubbard, RB; Smeeth, L; Tata, LJ	1
Chen, W; Wang, H	1
Boampong, VA; Boye, A; Martey, O; Takyi, N	1
Fu, Y; He, X; Liu, C; Pu, W; Qiu, L; Wang, C; Yuan, X; Zhang, X	1
Gotlib, D; Kurlander, J; Muzik, M; Perelstein, E; Riba, M; Zivin, K	1
Bigler, L; Bleul, C; Blom, H; Frisch, C; Linnebank, M; Prost, JC; Semmler, A; Smith, D	1
Gupta, S; Kruger, WD; Leclerc, D; Roy, M; Rozen, R; Wu, Q	1
Kluger, BM; Meador, KJ	1
Craig, JJ; Hunt, SJ; Irwin, B; Morrison, PJ; Morrow, JI; Parsons, L; Robertson, I; Russell, AJ; Smithson, WH; Waddell, R	1
Harden, CL; Sethi, NK	1
Bijlsma, JW; Bombardier, C; Boumpas, DT; Canhao, H; Carmona, L; Dougados, M; Edwards, CJ; Hamuryudan, V; Katchamart, W; Kvien, TK; Leeb, BF; Loza, E; Martín-Mola, EM; Martinez-Lopez, JA; Mielants, H; Müller-Ladner, U; Murphy, G; Pereira, IA; Ramos-Remus, C; Salliot, C; Trudeau, J; Valentini, G; van der Heijde, D; Visser, K; Zochling, J; Østergaard, M	1
Fanghanel, J; Gedrange, T; Gredes, T; Kubein-Meesenburg, D; Kundt, G; Proff, P; Weingartner, J	1
Gentile, S	1
Hauser, WA	1
Memon, S; Pratten, MK	1
Ornoy, A	1
Caldwell, PT; Howard, J; Manziello, A; Palbykin, B; Runyan, RB; Selmin, O	1
Caton, AR; Druschel, CM; Reefhuis, J; Roeleveld, N; van Gelder, MM; Werler, MM	1
Oosterbaan, AM; Steegers-Theunissen, RP; van Mil, NH	1
Bakker, MK; de Jong-van den Berg, LT; Jentink, J; Nijenhuis, CM; Wilffert, B	1
Cooney, CA; Downing, C; Johnson, TE; Larson, C; Leakey, TI; Rafferty, TM; Siegfried, RN	1
Deppe, C; Noachtar, S; Weil, S	1
Meyer, FP	1
Brien, JF; Collier, CP; Hewitt, AJ; Jefkins, MJ; Knuff, AL; Reynolds, JN	1
Altena, J; de Jong-van den Berg, LT; Tijink, L; van Gelder, MM; Wilffert, B	1
Auslender, R; Riskin-Mashiah, S	1
Bressenot, A; Bronowicki, JP; Chango, A; Forges, T; Guéant, JL; Namour, F; Pellanda, H	1
Guan, T; Guan, Z; Niu, B; Wang, J; Wang, M; Wang, X; Xiang, Q; Xie, Q; Zhang, T; Zhao, J	1
Karlov, VA; Kozhokaru, AB; Serkina, AV; Zhidkova, IA	1
Chaoui, R; Huch, A; Krähenmann, F; Stallmach, T; ØStensen, M	1
Hiilesmaa, V; Kaaja, E; Kaaja, R	1
Padmanabhan, R; Shafiullah, MM	1
Yerby, MS	1
Reynolds, PR; Schaalje, GB; Seegmiller, RE	1
Gjerstad, L; Henriksen, T; Husby, H; Taubøll, E	1
FELISATI, D	1
Källén, B	1
Finnell, RH; Merriweather, MY; Spiegelstein, O; Wicker, NJ	1
Brandl, KL; Carmichael, SL; Finnell, RH; Lammer, EJ; Rosenquist, TH; Shaw, GM	1
Oguni, M; Osawa, M	1
Honein, MA; Moore, CA; Yuskiv, N	1
Acharya, G; Johansen, SV; Kampman, MT; Stenvold, H	1
Li, Y; Long, Z; Shen, X; Tang, Y; Wang, J; Xu, Y; Zheng, X	1
Bozinov, D; Cabrera, RM; Finnell, RH; Hill, DS; Wlodarczyk, BJ; Zhu, H	1
Benedict, S; Nagelkerke, N; Padmanabhan, R; Shafiullah, M	1
Gutierrez, CM; Lima, GA; Machado, HR; Peres, LC; Ribeiro, CN; Yanaguita, MY	1
Christensen, J; Czeizel, AE; Horvath-Puhó, E; Kjaer, D; Olsen, J; Sørensen, HT; Vestergaard, M	1
Steinhoff, BJ	1
Cahal, DA; Griffin, JP; Weber, JC; Winship, KA	1
Biale, Y; Lewenthal, H	1
Chepenik, KP; Cotler, JM; Schmidt, RR; Slobodian, SA	1
DePaola, DP; Mandella, RD	1
Hunt, G; Oakeshott, P	1
Lindhout, D; Omtzigt, JG	1
Kokue, E; Kudo, G; Shimoda, M; Tsunematsu, K	1
Leppert, D; Wieser, HG	1
Foschi, N; Ortenzi, A; Paggi, A; Quattrini, A; Quattrini, C	1
Connelly, LE; Fu, SS; Keen, CL; Rogers, JM; Sakanashi, TM	1
Hishida, R; Nau, H	1
Morrell, MJ	1
Zahn, C	1
Craig, J; Morrison, P; Morrow, J; Patterson, V	1
Hernández-Díaz, S; Mitchell, AA; Walker, AM; Werler, MM	1
Loffredo, CA	1
Meador, KJ	1
Aderet, NB; Biale, Y; Lewenthal, H	1
Ben-Adereth, N; Biale, Y; Lewenthal, H	1
Elmazar, MM; Nau, H	1
Snodgrass, SR	1
Delgado-Escueta, AV; Janz, D	1
Nau, H; Wegner, C	1
Zhu, MX	1
Zhang, C; Zhou, SS	1
Klepel, H	1
Hawkins, DF	1
Andermann, E; Andermann, F; Dansky, LV; Rosenblatt, D; Sherwin, AL	1
Billings, RE; Hansen, DK	1
Seller, MJ	1
Davis, RE	1
Mercier-Parot, L; Tuchmann-Duplessis, H	1
Salter, AJ	1
Landauer, W; Wakasugi, N	1
Meadow, SR; Speidel, BD	1
Norris, JW; Pratt, RF	1
Mulherkar, L; Telang, NT	1
Jönsson, NA	1
Zellweger, H	1
Speidel, BD	1
Iles, CA; Leck, I; Sharman, IM; Toe, T; Wadsworth, GR	1
Faber, J; Gebhardt, DO	1
Pritchard, JA; Scott, DE; Whalley, PJ	1
Dörr, NW; Eckert, T	1
James, LF; Keeler, RF	1
Gontzea, I	1

Reviews

27 review(s) available for folic acid and Abnormalities, Drug-Induced

Article	Year
Epilepsy in Pregnancy-Management Principles and Focus on Valproate. International journal of molecular sciences, 2022, Jan-25, Volume: 23, Issue:3 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Epilepsy; Female; Folic Acid; Histone Deacetylase Inhibitors; Humans; Neural Tube Defects; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Valproic Acid	2022
[Study on the Safety of Perinatal Medication]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2021, Volume: 141, Issue:4 Topics: Abnormalities, Drug-Induced; Adult; Awareness; Breast Feeding; Cohort Studies; Databases, Factual; Dietary Supplements; Drug Information Services; Drug Labeling; Female; Folic Acid; Humans; Infant, Newborn; Japan; Neural Tube Defects; Pharmacists; Pregnancy; Prescription Drugs; Safety; Surveys and Questionnaires; Young Adult	2021
Preconception Care for the General Ob/Gyn. Clinical obstetrics and gynecology, 2018, Volume: 61, Issue:1 Topics: Abnormalities, Drug-Induced; Counseling; Environmental Exposure; Exercise; Female; Folic Acid; Genetic Carrier Screening; Humans; Infectious Disease Transmission, Vertical; Intimate Partner Violence; Medical History Taking; Preconception Care; Pregnancy; Smoking; Substance-Related Disorders; Teratogens; Vaccination Coverage; Vitamins	2018
Is post exposure prevention of teratogenic damage possible: Studies on diabetes, valproic acid, alcohol and anti folates in pregnancy: Animal studies with reflection to human. Reproductive toxicology (Elmsford, N.Y.), 2018, Volume: 80 Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; Diabetes, Gestational; Ethanol; Ethyl Ethers; Female; Folic Acid; Folic Acid Antagonists; Humans; Oxidative Stress; Pregnancy; Pregnancy in Diabetics; Prenatal Exposure Delayed Effects; Sulfhydryl Compounds; Teratogens; Valproic Acid	2018
[Epilepsy in pregnancy]. Harefuah, 2013, Volume: 152, Issue:8 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Counseling; Drug Monitoring; Epilepsy; Female; Folic Acid; Humans; Incidence; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome	2013
Guideline adherence for mentally ill reproductive-aged women on treatment with valproic acid: a retrospective chart review. The Journal of clinical psychiatry, 2016, Volume: 77, Issue:4 Topics: Abnormalities, Drug-Induced; Contraception Behavior; Female; Folic Acid; Guideline Adherence; Humans; Infant, Newborn; Mental Disorders; Neural Tube Defects; Neurocognitive Disorders; Patient Compliance; Pregnancy; Pregnancy Complications; Valproic Acid	2016
Teratogenicity of antiepileptic medications. Seminars in neurology, 2008, Volume: 28, Issue:3 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Folic Acid; Humans; Pregnancy; Risk Assessment; Risk Factors; Valproic Acid	2008
Epileptic disorders in pregnancy: an overview. Current opinion in obstetrics & gynecology, 2008, Volume: 20, Issue:6 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Folic Acid; Hemorrhage; Humans; Lamotrigine; Obstetrics; Pregnancy; Pregnancy Complications; Risk; Seizures; Triazines; Valproic Acid	2008
Valproic acid in pregnancy: how much are we endangering the embryo and fetus? Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 28, Issue:1 Topics: Abnormalities, Drug-Induced; Adolescent; Animals; Anticonvulsants; Autistic Disorder; Child; Child Development; Child, Preschool; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Fetus; Folic Acid; Humans; Infant; Maternal-Fetal Exchange; Milk, Human; Nervous System Diseases; Neural Tube Defects; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Risk Assessment; Semen; Syndrome; Teratogens; Valproic Acid	2009
Teratogenicity and underlying mechanisms of homocysteine in animal models: a review. Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 30, Issue:4 Topics: Abnormalities, Drug-Induced; Animals; Chickens; Congenital Abnormalities; Embryonic Development; Female; Fetal Development; Folic Acid; Homocysteine; Hyperhomocysteinemia; Mice; Neural Crest; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Rats; Teratogens	2010
Pharmacogenetics of drug-induced birth defects: what is known so far? Pharmacogenomics, 2011, Volume: 12, Issue:4 Topics: Abnormalities, Drug-Induced; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Congenital Abnormalities; Cyclooxygenase 2 Inhibitors; Female; Folic Acid; Folic Acid Antagonists; Genetic Association Studies; Humans; Oxidative Stress; Pharmacogenetics; Polymorphism, Single Nucleotide; Pregnancy; Serotonin 5-HT1 Receptor Antagonists; Teratogens	2011
Clinical care of pregnant women with epilepsy: neural tube defects and folic acid supplementation. Epilepsia, 2003, Volume: 44 Suppl 3 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Comorbidity; Critical Care; Dietary Supplements; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant, Newborn; Neural Tube Defects; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Product Surveillance, Postmarketing; Registries	2003
[Pregnancy and birth in women with epilepsy]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2003, Jun-12, Volume: 123, Issue:12 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Folic Acid; Genetic Counseling; Humans; Obstetric Labor Complications; Patient Care Planning; Patient Care Team; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Diagnosis; Risk Factors	2003
Gene-nutrient interactions: importance of folates and retinoids during early embryogenesis. Toxicology and applied pharmacology, 2004, Jul-15, Volume: 198, Issue:2 Topics: Abnormalities, Drug-Induced; Adult; Animals; Embryonic and Fetal Development; Female; Folic Acid; Gene Expression; Glycemic Index; Humans; Nutritional Physiological Phenomena; Pregnancy; Retinoids	2004
Epilepsy and pregnancy. Epilepsia, 2004, Volume: 45 Suppl 8 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Delivery, Obstetric; Drug Therapy, Combination; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant, Newborn; Maternal-Fetal Exchange; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk Factors	2004
Pregnancy, epilepsy, and anticonvulsants. Dialogues in clinical neuroscience, 2008, Volume: 10, Issue:1 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Fertility; Folic Acid; Humans; Pregnancy; Pregnancy Complications; Risk Assessment	2008
Teratogenic effects of antiepileptic drugs: implications for the management of epilepsy in women of childbearing age. Epilepsia, 1994, Volume: 35 Suppl 4 Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Anticonvulsants; Congenital Abnormalities; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Folic Acid; Genetic Counseling; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Risk Factors	1994
[Pregnancy, contraception and epilepsy]. Der Nervenarzt, 1993, Volume: 64, Issue:8 Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Contraception; Epilepsy; Female; Folic Acid; Free Radicals; Humans; Inactivation, Metabolic; Infant, Newborn; Pregnancy; Pregnancy Complications; Risk Factors; Vitamin K	1993
Guidelines for the care of women with epilepsy. Neurology, 1998, Volume: 51, Issue:5 Suppl 4 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Contraceptives, Oral; Contraindications; Dietary Supplements; Drug Interactions; Epilepsy; Female; Fertility; Folic Acid; Humans; Patient Compliance; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Teratogens	1998
Neurologic care of pregnant women with epilepsy. Epilepsia, 1998, Volume: 39 Suppl 8 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Disease Susceptibility; Epilepsy; Estrogens; Female; Folic Acid; Genetic Counseling; Hemorrhagic Disorders; Humans; Patient Education as Topic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Care; Risk Factors	1998
Epidemiology of cardiovascular malformations: prevalence and risk factors. American journal of medical genetics, 2000,Winter, Volume: 97, Issue:4 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anticonvulsants; Baltimore; Cardiovascular Abnormalities; Case-Control Studies; Diabetes, Gestational; District of Columbia; Female; Folic Acid; Humans; Infant; Infant, Newborn; Male; Maternal Exposure; Paternal Exposure; Pesticides; Pregnancy; Pregnancy Complications; Prevalence; Research Design; Risk Factors; Smoking; Solvents; Virginia	2000
Neurodevelopmental effects of antiepileptic drugs. Current neurology and neuroscience reports, 2002, Volume: 2, Issue:4 Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Brain; Epilepsy; Epoxy Compounds; Female; Folic Acid; Free Radicals; Humans; Ischemia; Mental Disorders; N-Methylaspartate; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk Factors; Teratogens	2002
Vitamin neurotoxicity. Molecular neurobiology, 1992,Spring, Volume: 6, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Avitaminosis; Blood-Brain Barrier; Carrier Proteins; Coenzymes; Drug Interactions; Folic Acid; Humans; Injections, Spinal; Liver; Methotrexate; Nervous System Diseases; Oxidation-Reduction; Pseudotumor Cerebri; Pyridoxine; Self Medication; Vitamin A; Vitamins	1992
Consensus guidelines: preconception counseling, management, and care of the pregnant woman with epilepsy. Neurology, 1992, Volume: 42, Issue:4 Suppl 5 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child Development; Child, Preschool; Counseling; Delivery, Obstetric; Epilepsy; Female; Fetal Growth Retardation; Fetus; Folic Acid; Growth; Humans; Labor, Obstetric; Postpartum Period; Pregnancy; Pregnancy Complications; Prenatal Care; Prenatal Diagnosis	1992
Teratogenesis and other adverse effects on the fetus of antimicrobial drugs used in pregnancy. Clinical and experimental obstetrics & gynecology, 1986, Volume: 13, Issue:3-4 Topics: Abnormalities, Drug-Induced; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Antitubercular Agents; Antiviral Agents; Female; Fetus; Folic Acid; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications	1986
Chemical structure and teratogenic properties. 3. A review of available data on structure-activity relationships and mechanism of action of thalidomide analogues. Acta pharmaceutica Suecica, 1972, Volume: 9, Issue:6 Topics: Abnormalities, Drug-Induced; Animals; Drug Interactions; Folic Acid; Glutamates; Humans; Hydrolysis; Immunosuppressive Agents; Nucleic Acids; Rabbits; Structure-Activity Relationship; Thalidomide; Uncoupling Agents	1972
Anticonvulsants during pregnancy: a danger to the developing fetus? Clinical pediatrics, 1974, Volume: 13, Issue:4 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Barbiturates; Blood Coagulation Disorders; Chromosome Aberrations; Chromosome Disorders; Female; Fetus; Folic Acid; Humans; Infant, Newborn; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Succinimides; Trimethadione; Vitamin K; Vitamin K Deficiency Bleeding	1974

Other Studies

82 other study(ies) available for folic acid and Abnormalities, Drug-Induced

Article	Year
Folic acid reduces the ethanol-induced morphological and behavioral defects in embryonic and larval zebrafish (Danio rerio) as a model for fetal alcohol spectrum disorder (FASD). Reproductive toxicology (Elmsford, N.Y.), 2020, Volume: 96 Topics: Abnormalities, Drug-Induced; Air Sacs; Animals; Behavior, Animal; Disease Models, Animal; Embryo, Nonmammalian; Ethanol; Eye Abnormalities; Female; Fetal Alcohol Spectrum Disorders; Folic Acid; Larva; Locomotion; Male; Sleep; Tail; Teratogens; Yolk Sac; Zebrafish	2020
Folic acid dose, valproate, and fetal malformations. Epilepsy & behavior : E&B, 2021, Volume: 114, Issue:Pt A Topics: Abnormalities, Drug-Induced; Anticonvulsants; Australia; Female; Folic Acid; Humans; Pregnancy; Pregnancy Complications; Valproic Acid	2021
Managing epilepsy in women of childbearing age - Polish Society of Epileptology and Polish Gynecological Society Guidelines. Ginekologia polska, 2017, Volume: 88, Issue:5 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Contraception; Delivery, Obstetric; Epilepsy; Female; Folic Acid; Gynecology; Humans; Neurology; Obstetrics; Poland; Postnatal Care; Preconception Care; Pregnancy; Pregnancy Complications; Prenatal Care; Societies, Medical; Vitamin B Complex	2017
Folic Acid Effect on Artemether-Induced Cardiac Anomalies in Mice Embryos. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2017, Volume: 27, Issue:9 Topics: Abnormalities, Drug-Induced; Animals; Artemether; Artemisinins; Female; Fetus; Folic Acid; Heart Defects, Congenital; Mice; Pregnancy; Pregnancy, Animal	2017
Fetal Valproate Syndrome - Still a Problem Today! Zeitschrift fur Geburtshilfe und Neonatologie, 2017, Volume: 221, Issue:5 Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Cesarean Section; Drug Therapy, Combination; Epilepsy; Female; Folic Acid; Humans; Infant, Newborn; Infant, Premature, Diseases; Lamotrigine; Male; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Risk Factors; Syndrome; Valproic Acid	2017
Epilepsy in pregnancy - a collaborative team effort of obstetricians, neurologists and primary care physicians for a successful outcome. Australian family physician, 2014, Volume: 43, Issue:3 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Contraceptive Agents; Dietary Supplements; Epilepsy; Female; Fertility; Folic Acid; General Practice; Humans; Interdisciplinary Communication; Neurology; Obstetrics; Patient Care Team; Postnatal Care; Preconception Care; Pregnancy; Pregnancy Complications; Prenatal Care; Vitamin K	2014
Brief report novel mechanism for valproate-induced teratogenicity. Birth defects research. Part A, Clinical and molecular teratology, 2014, Volume: 100, Issue:8 Topics: Abnormalities, Drug-Induced; Biological Availability; Cell Line; Embryonic Development; Female; Folate Receptors, GPI-Anchored; Folic Acid; HEK293 Cells; Humans; Neural Tube Defects; Pregnancy; Protein Binding; Teratogens; Valproic Acid; Vitamin B Complex	2014
[The antagonistic effect of folic acid and resveratrol on cleft palate in mice induced by TCDD]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2013, Volume: 29, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Fetus; Folic Acid; Humans; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Pregnancy; Random Allocation; Resveratrol; Stilbenes; Teratogens	2013
[Tetrachlorodibenzo-p-dioxin-induced cleft palate because of partial loss of cell polarity to interfere with apoptosis during early developmental stage]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2014, Volume: 49, Issue:12 Topics: Abnormalities, Drug-Induced; Animals; Apoptosis; Biomarkers; Cell Polarity; Cleft Palate; Disease Models, Animal; Female; Fetus; Folic Acid; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Pregnancy; Receptors, Aryl Hydrocarbon; RNA, Messenger; Teratogens; Transforming Growth Factor beta3	2014
Congenital Anomalies in Children of Mothers Taking Antiepileptic Drugs with and without Periconceptional High Dose Folic Acid Use: A Population-Based Cohort Study. PloS one, 2015, Volume: 10, Issue:7 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cohort Studies; Comorbidity; Congenital Abnormalities; Dose-Response Relationship, Drug; Drug Prescriptions; Drug Utilization; Epilepsy; Female; Folic Acid; Humans; Odds Ratio; Organogenesis; Overweight; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prenatal Care; Risk; Sample Size; Smoking; United Kingdom; Young Adult	2015
Dose-Dependent Antiteratogenic Effects of Folic Acid on All-Trans Retinoic Acid-Induced Cleft Palate in Fetal Mice. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2016, Volume: 53, Issue:6 Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Folic Acid; Maternal Exposure; Mice; Mice, Inbred C57BL; Pregnancy; Prenatal Care; Teratogens; Tretinoin	2016
Trimethoprim during the 3 months before pregnancy: malformations in children. Prescrire international, 2016, Volume: 25, Issue:167 Topics: Abnormalities, Drug-Induced; Anti-Infective Agents, Urinary; Female; Folic Acid; Folic Acid Antagonists; Humans; Pregnancy; Trimethoprim	2016
Assessment of an aqueous seed extract of Parkia clappertoniana on reproductive performance and toxicity in rodents. Journal of ethnopharmacology, 2016, Jun-05, Volume: 185 Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Fabaceae; Female; Folic Acid; Male; Mice; Plant Extracts; Pregnancy; Rats; Rats, Sprague-Dawley; Reproduction; Seeds; Toxicity Tests	2016
Comparative Study of Folic Acid and α-Naphthoflavone on Reducing TCDD-Induced Cleft Palate in Fetal Mice. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2017, Volume: 54, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; Benzoflavones; Cleft Palate; Female; Folic Acid; Immunohistochemistry; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Polychlorinated Dibenzodioxins; Pregnancy; Random Allocation	2017
Intrauterine valproate exposure is associated with alterations in hippocampal cell numbers and folate metabolism in a rat model of valproate teratogenicity. Seizure, 2017, Volume: 46 Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Astrocytes; Cell Count; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Female; Folic Acid; Hippocampus; Homocysteine; Liver; Male; Neurogenesis; Neurons; Organ Size; Rats, Wistar; Valproic Acid	2017
Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency. Journal of cellular biochemistry, 2008, Oct-01, Volume: 105, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; Brain; Cell Line, Tumor; Female; Folic Acid; Homocysteine; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Pregnancy; Teratogens; Up-Regulation; Valproic Acid	2008
Folic acid use and major congenital malformations in offspring of women with epilepsy: a prospective study from the UK Epilepsy and Pregnancy Register. Journal of neurology, neurosurgery, and psychiatry, 2009, Volume: 80, Issue:5 Topics: Abnormalities, Drug-Induced; Adult; Cleft Palate; Dietary Supplements; Drug Utilization; Epilepsy; Female; Folic Acid; Follow-Up Studies; Guidelines as Topic; Heart Defects, Congenital; Humans; Hypospadias; Infant, Newborn; Male; Neural Tube Defects; Pregnancy; Prospective Studies; Registries; United Kingdom; Vitamins; Young Adult	2009
Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Annals of the rheumatic diseases, 2009, Volume: 68, Issue:7 Topics: Abnormalities, Drug-Induced; Administration, Oral; Antirheumatic Agents; Drug Therapy, Combination; Evidence-Based Medicine; Female; Folic Acid; Humans; Long-Term Care; Male; Methotrexate; Preconception Care; Rheumatic Diseases; Risk Factors	2009
Different bone sesitivity to malformations induced by procarbazine in fetal rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59 Suppl 5 Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cleft Palate; Drug Therapy, Combination; Female; Fetal Development; Folic Acid; Gestational Age; Pregnancy; Procarbazine; Rats; Rats, Inbred Lew; Thiocyanates	2008
Topiramate in pregnancy and breastfeeding. Clinical drug investigation, 2009, Volume: 29, Issue:2 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Dietary Supplements; Epilepsy; Female; Folic Acid; Fructose; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Human; Pregnancy; Risk Assessment; Topiramate; Vitamins; Young Adult	2009
Folic acid supplementation: too much of a good thing? Journal of neurology, neurosurgery, and psychiatry, 2009, Volume: 80, Issue:5 Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Dietary Supplements; Female; Folic Acid; Humans; Infant, Newborn; Pregnancy; Vitamins; Young Adult	2009
Developmental toxicity of ethanol in chick heart in ovo and in micromass culture can be prevented by addition of vitamin C and folic acid. Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 28, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Cell Survival; Cells, Cultured; Chick Embryo; Drug Antagonism; Embryo Loss; Ethanol; Fetal Weight; Folic Acid; Heart; Heart Defects, Congenital; In Vitro Techniques; Myocytes, Cardiac	2009
Gene expression profiling in the fetal cardiac tissue after folate and low-dose trichloroethylene exposure. Birth defects research. Part A, Clinical and molecular teratology, 2010, Volume: 88, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; Apoptosis; Cell Differentiation; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Gene Expression Profiling; Heart; Heart Defects, Congenital; Ion Channels; Ion Transport; Mice; Organogenesis; Pregnancy; Rats; Teratogens; Trichloroethylene; Water Pollutants, Chemical	2010
Characteristics of pregnant illicit drug users and associations between cannabis use and perinatal outcome in a population-based study. Drug and alcohol dependence, 2010, Jun-01, Volume: 109, Issue:1-3 Topics: Abnormalities, Drug-Induced; Adult; Birth Weight; Case-Control Studies; Central Nervous System Stimulants; Cocaine-Related Disorders; Female; Folic Acid; Gestational Age; Humans; Infant, Low Birth Weight; Infant, Newborn; Marijuana Abuse; Obstetric Labor, Premature; Population; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Risk Factors; Smoking; Socioeconomic Factors; Substance-Related Disorders; Young Adult	2010
Does folic acid use decrease the risk for spina bifida after in utero exposure to valproic acid? Pharmacoepidemiology and drug safety, 2010, Volume: 19, Issue:8 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Humans; Infant, Newborn; Pregnancy; Pregnancy Trimester, First; Risk Factors; Spinal Dysraphism; Valproic Acid	2010
Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet. Alcohol (Fayetteville, N.Y.), 2011, Volume: 45, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; Betaine; Choline; Diet; DNA Methylation; Drug Resistance; Ethanol; Female; Fetal Death; Fetal Development; Folic Acid; Gene Expression; Genomic Imprinting; Insulin-Like Growth Factor II; Male; Maternal-Fetal Exchange; Methanol; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Species Specificity; Vitamin B 12	2011
The treatment of women with epilepsy. Deutsches Arzteblatt international, 2010, Volume: 107, Issue:45 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anticonvulsants; Contraceptives, Oral; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Epilepsy; Female; Folic Acid; Germany; Humans; Infant, Newborn; Polycystic Ovary Syndrome; Preconception Care; Pregnancy; Risk Factors	2010
Step down treatment with antiepileptic drugs. Deutsches Arzteblatt international, 2011, Volume: 108, Issue:5 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anticonvulsants; Contraceptives, Oral; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Epilepsy; Female; Folic Acid; Germany; Humans; Infant, Newborn; Polycystic Ovary Syndrome; Preconception Care; Pregnancy; Risk Factors	2011
Chronic ethanol exposure and folic acid supplementation: fetal growth and folate status in the maternal and fetal guinea pig. Reproductive toxicology (Elmsford, N.Y.), 2011, Volume: 31, Issue:4 Topics: Abnormalities, Drug-Induced; Alcohol Drinking; Animals; Brain; Dietary Supplements; Erythrocytes; Ethanol; Female; Fetal Blood; Fetal Resorption; Fetal Weight; Folic Acid; Gestational Age; Guinea Pigs; Hippocampus; Litter Size; Male; Maternal Exposure; Organ Size; Pregnancy; Vitamin B Complex	2011
Periconceptional folic acid and teratogenic drug use in women undergoing fertility treatments. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:10 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Cohort Studies; Congenital Abnormalities; Drug Prescriptions; Drug Utilization; Female; Folic Acid; Humans; Israel; Middle Aged; Preconception Care; Pregnancy; Quality of Health Care; Reproductive Techniques, Assisted; Retrospective Studies; Teratogens; Vitamin B Complex; Young Adult	2012
Fumonisin FB1 treatment acts synergistically with methyl donor deficiency during rat pregnancy to produce alterations of H3- and H4-histone methylation patterns in fetuses. Molecular nutrition & food research, 2012, Volume: 56, Issue:6 Topics: Abnormalities, Drug-Induced; Animals; Choline Deficiency; Fatty Liver; Female; Folic Acid; Folic Acid Deficiency; Folic Acid Transporters; Fumonisins; Gene Expression Regulation, Developmental; Heterochromatin; Histones; Liver; Maternal Nutritional Physiological Phenomena; Methylation; Neural Tube Defects; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; Teratogens; Vitamin B 12 Deficiency	2012
Influence of the antifolate drug Methotrexate on the development of murine neural tube defects and genomic instability. Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:9 Topics: Abnormalities, Drug-Induced; Animals; Chromatography, Liquid; Comparative Genomic Hybridization; Diet; DNA Copy Number Variations; Dose-Response Relationship, Drug; Embryonic Development; Enzyme Inhibitors; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Genomic Instability; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neural Tube; Neural Tube Defects; Pregnancy; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Tandem Mass Spectrometry; Tetrahydrofolate Dehydrogenase	2013
[Stigmata of dysembryogenesis and physical development in children born to mothers with epilepsy]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011, Volume: 111, Issue:5 Pt 2 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child Development; Child, Preschool; Developmental Disabilities; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Parturition; Pregnancy; Pregnancy Complications; Valproic Acid	2011
In utero first trimester exposure to low-dose methotrexate with increased fetal nuchal translucency and associated malformations. Prenatal diagnosis, 2002, Volume: 22, Issue:6 Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Rheumatoid; Female; Folic Acid; Gestational Age; Heart Septal Defects; Hernia, Diaphragmatic; Humans; Methotrexate; Neck; Pregnancy; Pregnancy Complications; Ultrasonography, Prenatal	2002
Major malformations in offspring of women with epilepsy. Neurology, 2003, Feb-25, Volume: 60, Issue:4 Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Comorbidity; Educational Status; Epilepsy; Female; Finland; Folic Acid; Follow-Up Studies; Humans; Incidence; Logistic Models; Odds Ratio; Oxcarbazepine; Pregnancy; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; Risk Factors; Valproic Acid	2003
Amelioration of sodium valproate-induced neural tube defects in mouse fetuses by maternal folic acid supplementation during gestation. Congenital anomalies, 2003, Volume: 43, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; Brain; Dietary Supplements; Disease Models, Animal; Enzyme Inhibitors; Female; Folic Acid; Maternal Exposure; Mice; Neural Tube Defects; Time Factors; Valproic Acid; Vitamin B 12	2003
Combination therapy with folic acid and methionine in the prevention of retinoic acid-induced cleft palate in mice. Birth defects research. Part A, Clinical and molecular teratology, 2003, Volume: 67, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cleft Palate; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid; Injections, Intraperitoneal; Methionine; Mice; Pregnancy; Teratogens; Tretinoin	2003
TERATOGENIC ACTION OF THALIDOMIDE. Lancet (London, England), 1964, Mar-28, Volume: 1, Issue:7335 Topics: Abnormalities, Drug-Induced; Female; Folic Acid; Glutamine; Niacinamide; Pregnancy; Pregnancy Complications; Pregnancy, Animal; Rabbits; Riboflavin; Teratogens; Thalidomide; Toxicology; Vitamin B Deficiency	1964
Maternal drug use and infant cleft lip/palate with special reference to corticoids. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2003, Volume: 40, Issue:6 Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Cleft Lip; Cleft Palate; Confidence Intervals; Female; Folic Acid; Glucocorticoids; Humans; Infant, Newborn; Naproxen; Odds Ratio; Pharmaceutical Preparations; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Registries; Sulfasalazine; Sweden; Vitamins	2003
Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice. Birth defects research. Part A, Clinical and molecular teratology, 2003, Volume: 67, Issue:12 Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carrier Proteins; Diet; Disease Models, Animal; Embryo Loss; Female; Folate Receptors, GPI-Anchored; Folic Acid; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Neural Tube Defects; Pregnancy; Receptors, Cell Surface; Valproic Acid	2003
Reported multivitamin consumption and the occurrence of multiple congenital anomalies. American journal of medical genetics. Part A, 2005, Jul-01, Volume: 136, Issue:1 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Case-Control Studies; Dietary Supplements; Female; Folic Acid; Georgia; Humans; Infant, Newborn; Maternal Age; Odds Ratio; Preconception Care; Pregnancy; Pregnancy Trimester, First; Risk Assessment; Risk Factors; Urethral Obstruction; Vitamins	2005
Management of women with epilepsy: Are guidelines being followed? Results from case-note reviews and a patient questionnaire. Epilepsia, 2005, Volume: 46, Issue:8 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Attitude to Health; Epilepsy; Female; Folic Acid; Guideline Adherence; Health Services Research; Humans; Information Dissemination; Medical Audit; Medical Records Systems, Computerized; Patient Education as Topic; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Quality Assurance, Health Care; Quality Indicators, Health Care; Sex Factors; Surveys and Questionnaires; Women's Health	2005
The maternal combined supplementation of folic acid and Vitamin B(12) suppresses ethanol-induced developmental toxicity in mouse fetuses. Reproductive toxicology (Elmsford, N.Y.), 2006, Volume: 22, Issue:1 Topics: Abnormalities, Drug-Induced; Alcoholic Intoxication; Animals; Bone and Bones; Dietary Supplements; Embryo Implantation; Embryo Loss; Ethanol; Female; Fetal Development; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Mice; Pregnancy; Vitamin B 12	2006
Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. Neurotoxicology, 2006, Volume: 27, Issue:4 Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Arsenic; Biological Transport; Carrier Proteins; Embryo, Mammalian; Ephrins; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gene Expression; Gene Expression Regulation, Developmental; Homeodomain Proteins; Mice; Mice, Knockout; Microarray Analysis; Neural Tube Defects; Platelet-Derived Growth Factor; Pregnancy; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2006
Effect of maternal exposure to homocystine on sodium valproate-induced neural tube defects in the mouse embryos. European journal of nutrition, 2006, Volume: 45, Issue:6 Topics: Abnormalities, Drug-Induced; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Homocystine; Mice; Neural Tube Defects; Pregnancy; Random Allocation; Teratogens; Valproic Acid; Vitamin B 12	2006
Pregnancy outcome in ethanol-treated mice with folic acid supplementation in saccharose. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2008, Volume: 24, Issue:1 Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Central Nervous System Depressants; Dietary Supplements; Ethanol; Female; Fetal Growth Retardation; Fetal Weight; Folic Acid; Gestational Age; Injections, Intraperitoneal; Male; Maternal Exposure; Mice; Neural Tube Defects; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Sucrose	2008
Antiepileptic drug use, folic acid supplementation, and congenital abnormalities: a population-based case-control study. BJOG : an international journal of obstetrics and gynaecology, 2008, Volume: 115, Issue:1 Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Case-Control Studies; Epilepsy; Female; Folic Acid; Humans; Male; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First	2008
Maternal drug histories and central nervous system anomalies. Archives of disease in childhood, 1984, Volume: 59, Issue:11 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Anti-Inflammatory Agents; Female; Folic Acid; Humans; Maternal Age; Middle Aged; Neural Tube Defects; Pregnancy; Pregnancy Trimester, First; Salicylates; Sulfasalazine	1984
Effect of folic acid supplementation on congenital malformations due to anticonvulsive drugs. European journal of obstetrics, gynecology, and reproductive biology, 1984, Volume: 18, Issue:4 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Female; Folic Acid; Humans; Infant, Newborn; Male; Phenytoin; Pregnancy; Pregnancy Complications; Prospective Studies; Retrospective Studies	1984
Effect of a synthetic folic acid analogue, 9-methyl-pteroylglutamic acid, on fetal chondrogenesis: ultrastructural observations. Biology of the neonate, 1983, Volume: 43, Issue:5-6 Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Female; Fetus; Folic Acid; Folic Acid Antagonists; Male; Rats; Tibia	1983
Folate deficiency and in vitro palatogenesis I: effects of a folate-deficient culture on rabbit palate fusion and folate pools. Journal of craniofacial genetics and developmental biology, 1981, Volume: 1, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; DNA; Female; Folic Acid; Folic Acid Deficiency; In Vitro Techniques; Methotrexate; Palate; Pregnancy; Rabbits	1981
Prevention of neural tube defects. Lancet (London, England), 1994, Jan-08, Volume: 343, Issue:8889 Topics: Abnormalities, Drug-Induced; Carbamazepine; Female; Folic Acid; Humans; Neural Tube Defects; Pregnancy; Spinal Dysraphism; Valproic Acid	1994
Effects of folic acid on pyrimethamine teratogenesis in rats. Advances in experimental medicine and biology, 1993, Volume: 338 Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Drug Synergism; Embryo, Mammalian; Female; Folic Acid; Injections, Intraperitoneal; Leucovorin; Mice; Mice, Inbred ICR; Pregnancy; Pyrimethamine; Rats; Rats, Wistar; Teratogens	1993
Lamotrigine and pregnancy. Italian journal of neurological sciences, 1996, Volume: 17, Issue:6 Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Female; Folic Acid; Humans; Lamotrigine; Pregnancy; Triazines	1996
Influence of maternal folate status on the developmental toxicity of methanol in the CD-1 mouse. Teratology, 1996, Volume: 54, Issue:4 Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Embryo, Mammalian; Embryonic and Fetal Development; Female; Folic Acid; Folic Acid Deficiency; Hematocrit; Liver; Methanol; Mice; Organ Size; Pregnancy; Reproduction; Uterus	1996
VPA-induced neural tube defects in mice. I. Altered metabolism of sulfur amino acids and glutathione. Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:2 Topics: Abnormalities, Drug-Induced; Amino Acids; Animals; Anticonvulsants; Female; Folic Acid; Glutathione; Homocysteine; Liver; Methionine; Mice; Neural Tube Defects; Pregnancy; Valproic Acid	1998
Failure of periconceptual folic acid to prevent a neural tube defect in the offspring of a mother taking sodium valproate. Seizure, 1999, Volume: 8, Issue:4 Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Epilepsy, Generalized; Female; Folic Acid; Humans; Infant, Newborn; Male; Neural Tube Defects; Pregnancy; Pregnancy Complications; Risk; Treatment Failure; Valproic Acid	1999
Folic acid antagonists during pregnancy and the risk of birth defects. The New England journal of medicine, 2000, Nov-30, Volume: 343, Issue:22 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Case-Control Studies; Cleft Lip; Dietary Supplements; Female; Folic Acid; Folic Acid Antagonists; Heart Defects, Congenital; Humans; Logistic Models; Pregnancy; Urinary Tract; Vitamins	2000
Congenital malformations due to anticonvulsive drugs. Obstetrics and gynecology, 1975, Volume: 45, Issue:4 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Order; Cleft Lip; Cleft Palate; Epilepsy; Female; Fetal Death; Folic Acid; Folic Acid Antagonists; Hemorrhage; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Trimethadione	1975
Letter: Congenital malformations and decreased blood level of folic acid induced by antiepileptic drugs. Acta obstetricia et gynecologica Scandinavica, 1976, Volume: 55, Issue:2 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Female; Folic Acid; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications	1976
Methotrexate increases valproic acid-induced developmental toxicity, in particular neural tube defects in mice. Teratogenesis, carcinogenesis, and mutagenesis, 1992, Volume: 12, Issue:5 Topics: Abnormalities, Drug-Induced; Animals; Drug Synergism; Encephalocele; Female; Folic Acid; Methotrexate; Mice; Neural Tube Defects; Pregnancy; Valproic Acid	1992
Diurnal variation of folate concentrations in mouse embryo and plasma: the protective effect of folinic acid on valproic-acid-induced teratogenicity is time dependent. Reproductive toxicology (Elmsford, N.Y.), 1991, Volume: 5, Issue:6 Topics: Abnormalities, Drug-Induced; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Decidua; Embryo, Mammalian; Female; Fetal Resorption; Folic Acid; Leucovorin; Mice; Mice, Inbred Strains; Neural Tube Defects; Pregnancy; Valproic Acid	1991
[Effect of diphenylhydantoin sodium in causing deformity and that of folic acid preparations for its prevention]. Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1990, Volume: 23, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; Female; Folic Acid; Phenytoin; Pregnancy; Rats; Rats, Inbred Strains	1990
[Preventive effects of fortified pollen on diphenylhydantoin teratogenesis]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1989, Volume: 20, Issue:4 Topics: Abnormalities, Drug-Induced; Animals; Drug Synergism; Female; Folic Acid; Phenytoin; Pollen; Pregnancy; Rats; Rats, Inbred Strains	1989
[Epilepsy and pregnancy--principles of therapy]. Psychiatrie, Neurologie, und medizinische Psychologie, 1986, Volume: 38, Issue:2 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Epilepsy; Female; Folic Acid; Humans; Infant, Newborn; Kinetics; Long-Term Care; Pregnancy; Pregnancy Complications; Vitamin K	1986
Anticonvulsants, folate levels, and pregnancy outcome: a prospective study. Annals of neurology, 1987, Volume: 21, Issue:2 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Folic Acid; Humans; Pregnancy; Pregnancy Complications; Prospective Studies	1987
Phenytoin teratogenicity and effects on embryonic and maternal folate metabolism [published errtum appears in Teratology 1986 Dec;34(3):487]. Teratology, 1985, Volume: 31, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Embryo Implantation; Female; Folic Acid; Litter Size; Liver; Maternal-Fetal Exchange; Mice; Phenytoin; Pregnancy	1985
Prevention of neural tube defects in a mouse model and in man. Progress in clinical and biological research, 1985, Volume: 163C Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Folic Acid; Gestational Age; Humans; Mice; Neural Tube Defects; Pregnancy; Vitamin A	1985
Congenital malformations and anticonvulsant drugs. Lancet (London, England), 1973, Mar-03, Volume: 1, Issue:7801 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Female; Folic Acid; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy	1973
The dysmorphogenic potential of phenytoin: experimental observations. Drugs, 1974, Volume: 8, Issue:5 Topics: Abnormalities, Drug-Induced; Animals; Epilepsy; Female; Fetus; Folic Acid; Folic Acid Deficiency; Haplorhini; Humans; Mice; Phenytoin; Pregnancy; Pregnancy Complications; Rats; Teratogens	1974
The toxicity profile of trimethoprim-sulphamethoxazole after four years of widespread use. The Medical journal of Australia, 1973, Jun-30, Volume: 1, Issue:2 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Anti-Infective Agents; Child; Child, Preschool; Chromosome Aberrations; Drug Combinations; Drug Eruptions; Female; Folic Acid; Folic Acid Antagonists; Gastrointestinal Diseases; Haplorhini; Hematologic Diseases; Humans; Infant; Infant, Newborn; Kidney Diseases; Lymphatic Diseases; Lymphocyte Activation; Male; Middle Aged; Pregnancy; Pyrimidines; Rats; Sulfamethoxazole; Thyroid Neoplasms; Trimethoprim	1973
Teratological studies with sulphonamides and their implications. Journal of embryology and experimental morphology, 1968, Volume: 20, Issue:3 Topics: Abnormalities, Drug-Induced; Adenine Nucleotides; Animals; Carbonic Anhydrase Inhibitors; Chick Embryo; Chloramines; Dichlorphenamide; Drug Synergism; Folic Acid; Methazolamide; NAD; Pyridines; Sulfanilamides; Sulfonamides; Time Factors	1968
Epilepsy, anticonvulsants and congenital malformations. Drugs, 1974, Volume: 8, Issue:5 Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Female; Folic Acid; Humans; Mice; Pregnancy; Pregnancy Complications; Rabbits; Rats; Socioeconomic Factors	1974
Folic acid deficiency and epilepsy. Drugs, 1974, Volume: 8, Issue:5 Topics: Abnormalities, Drug-Induced; Absorption; Anticonvulsants; Brain; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Mental Disorders; Pregnancy; Pregnancy Complications	1974
In vitro studies on the effect of hydrazine on the morphogenesis of chick embryos and the mechanism of its action. Oncology, 1974, Volume: 30, Issue:6 Topics: Abnormalities, Drug-Induced; Amino Acids; Animals; Brain; Chick Embryo; Culture Techniques; Folic Acid; Heart; Hydrazines; Methylation; Morphogenesis; Vitamin B 12	1974
Folic acid deficiency and congenital malformation. Developmental medicine and child neurology, 1973, Volume: 15, Issue:1 Topics: Abnormalities, Drug-Induced; Barbiturates; Congenital Abnormalities; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Gestational Age; Humans; Hydantoins; Pregnancy; Pregnancy Complications, Hematologic	1973
Proceedings: A study of the extent to which maternal nutrition after delivery reflects the situation in early pregnancy. British journal of preventive & social medicine, 1974, Volume: 28, Issue:1 Topics: Abnormalities, Drug-Induced; Carotenoids; Diet; Female; Folic Acid; Humans; Nutrition Disorders; Postpartum Period; Pregnancy; Pregnancy Complications; Vitamin A	1974
The influence of aminopterin on limb regeneration in Ambystoma mexicanum. Journal of embryology and experimental morphology, 1966, Volume: 16, Issue:1 Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Extremities; Folic Acid; Leucovorin; Regeneration; Urodela	1966
Maternal folate deficiency and pregnancy wastage. IV. Effects of folic acid supplements, anticonvulsants, and oral contraceptives. American journal of obstetrics and gynecology, 1971, Feb-01, Volume: 109, Issue:3 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anemia, Macrocytic; Anemia, Sickle Cell; Anemia, Sideroblastic; Anticonvulsants; Birth Weight; Contraceptives, Oral; Drug Antagonism; Epilepsy; Female; Fetus; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Hemoglobinometry; Humans; Hypertension; Infant Mortality; Infant, Newborn; Infant, Premature; Iron; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications	1971
[Intermolecular interaction of folic acid with N-phthaloyl-DL-glutamic acid. Teratogenic effect of thalidomide]. Experientia, 1971, Volume: 27, Issue:6 Topics: Abnormalities, Drug-Induced; Chemical Phenomena; Chemistry; Dioxins; Folic Acid; Solubility; Thalidomide	1971
Teratogenic effects of aminopterin in sheep. Teratology, 1968, Volume: 1, Issue:4 Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Ear; Female; Folic Acid; Forelimb; Hindlimb; Kyphosis; Mandible; Plant Poisoning; Pregnancy; Scoliosis; Sheep; Torticollis	1968
[Abnormalities due to defective diet. I. Experiments with mammals and observations in humans]. Nutritio et dieta; European review of nutrition and dietetics, 1969, Volume: 11, Issue:1 Topics: Abnormalities, Drug-Induced; Abortion, Criminal; Abortion, Legal; Aminopterin; Animals; Congenital Abnormalities; Deficiency Diseases; Female; Folic Acid; Humans; Hyperemesis Gravidarum; Maternal-Fetal Exchange; Pantothenic Acid; Pregnancy; Pregnancy Complications; Riboflavin; Socioeconomic Factors; Starvation; Swine; Vitamin A	1969