fluticasone-propionate has been researched along with Pulmonary-Disease--Chronic-Obstructive* in 1 studies
1 other study(ies) available for fluticasone-propionate and Pulmonary-Disease--Chronic-Obstructive
| Article | Year |
|---|---|
Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma.
The discovery of a novel series of therapeutic agents that has been designed and optimized for treating chronic obstructive pulmonary disease is reported. The pharmacological strategy was based on the identification of compounds that inhibit a defined subset of kinase enzymes modulating inflammatory processes that would be effective against steroid refractory disease and exhibit a sustained duration of action after inhaled delivery. Topics: Animals; Asthma; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance; Humans; Male; Mice; Mice, Inbred Strains; Molecular Structure; Protein Kinase Inhibitors; Protein Kinases; Pulmonary Disease, Chronic Obstructive; Steroids; Structure-Activity Relationship; U937 Cells | 2016 |