flutamide has been researched along with Testicular Diseases in 4 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Testicular Diseases: Pathological processes of the TESTIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The dose-response characterization of endocrine mediated toxicity is an on-going debate which is controversial when exploring the nature of the dose-response curve and the effect at the low-end of the curve." | 1.42 | Low dose evaluation of the antiandrogen flutamide following a Mode of Action approach. ( Bars, R; Hilmi, C; Pallardy, M; Rouquié, D; Sarrabay, A; Schorsch, F; Tinwell, H, 2015) |
| "The safety assessment of chemicals for humans relies on identifying no-observed adverse effect levels (NOAELs) in animal toxicity studies using standard methods." | 1.37 | A molecular and phenotypic integrative approach to identify a no-effect dose level for antiandrogen-induced testicular toxicity. ( Bars, R; Cavaillé, C; Ludwig, S; Pallardy, M; Rouquié, D; Schorsch, F; Tinwell, H, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sarrabay, A | 1 |
| Hilmi, C | 1 |
| Tinwell, H | 2 |
| Schorsch, F | 2 |
| Pallardy, M | 2 |
| Bars, R | 2 |
| Rouquié, D | 2 |
| Macleod, DJ | 1 |
| Sharpe, RM | 1 |
| Welsh, M | 1 |
| Fisken, M | 1 |
| Scott, HM | 1 |
| Hutchison, GR | 1 |
| Drake, AJ | 1 |
| van den Driesche, S | 1 |
| Ludwig, S | 1 |
| Cavaillé, C | 1 |
| Unger, PD | 1 |
| Wang, Q | 1 |
| Gordon, RE | 1 |
| Stock, R | 1 |
| Stone, N | 1 |
4 other studies available for flutamide and Testicular Diseases
| Article | Year |
|---|---|
Low dose evaluation of the antiandrogen flutamide following a Mode of Action approach.
Topics: Androgen Antagonists; Animals; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Leydig | 2015 |
Androgen action in the masculinization programming window and development of male reproductive organs.
Topics: Androgen Antagonists; Androgens; Animals; Animals, Newborn; Dibutyl Phthalate; Female; Flutamide; Ge | 2010 |
A molecular and phenotypic integrative approach to identify a no-effect dose level for antiandrogen-induced testicular toxicity.
Topics: Androgen Antagonists; Animals; Dose-Response Relationship, Drug; Flutamide; Gene Expression Regulati | 2011 |
Localized amyloidosis of the seminal vesicle. Possible association with hormonally treated prostatic adenocarcinoma.
Topics: Adenocarcinoma; Aged; Amyloidosis; Androgen Antagonists; Antineoplastic Agents, Hormonal; beta 2-Mic | 1997 |