Page last updated: 2024-10-27

flutamide and Soft Tissue Neoplasms

flutamide has been researched along with Soft Tissue Neoplasms in 4 studies

Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.

Research Excerpts

ExcerptRelevanceReference
"We randomly assigned patients who had never received antiandrogen therapy and who had distant metastases from adenocarcinoma of the prostate to treatment with bilateral orchiectomy and either flutamide or placebo."5.08Bilateral orchiectomy with or without flutamide for metastatic prostate cancer. ( Blumenstein, BA; Bueschen, AJ; Crawford, ED; Culkin, DJ; Eisenberger, MA; Loehrer, PJ; Lowe, BA; McLeod, DG; Miller, G; Sears, K; Thompson, IM; Wilding, G, 1998)
"For good prognosis metastatic prostate cancer patients under anti-androgen treatment, PSA response at 6 months with cut-off levels of < or = 1 ng/ml and < or = 10 ng/ml is prognostic for survival."2.71Prostate specific antigen: a prognostic marker of survival in good prognosis metastatic prostate cancer? (EORTC 30892). ( Collette, L; de Reijke, TM; Schröder, FH, 2003)
") monotherapy at a daily dose of 100 mg, which is the most commonly used dosage in Japan for patients with prostatic cancer."2.67A randomized phase II trial of flutamide vs chlormadinone acetate in previously untreated advanced prostatic cancer. The Japan Flutamide Study Group. ( Akaza, H; Aso, Y; Koiso, K; Kotake, T; Usami, M, 1993)
"Flutamide appears to be a safe antiandrogen, usually effective in the management of patients with advanced prostatic cancer who have had no prior endocrine therapy."2.65Experience with flutamide in patients with advanced prostatic cancer without prior endocrine therapy. ( Sogani, PC; Vagaiwala, MR; Whitmore, WF, 1984)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Collette, L1
de Reijke, TM1
Schröder, FH1
Sogani, PC1
Vagaiwala, MR1
Whitmore, WF1
Akaza, H1
Usami, M1
Kotake, T1
Koiso, K1
Aso, Y1
Eisenberger, MA1
Blumenstein, BA1
Crawford, ED1
Miller, G1
McLeod, DG1
Loehrer, PJ1
Wilding, G1
Sears, K1
Culkin, DJ1
Thompson, IM1
Bueschen, AJ1
Lowe, BA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Collection of Blood From Patients With Prostate Cancer[NCT00923221]1,000 participants (Anticipated)Observational2007-02-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for flutamide and Soft Tissue Neoplasms

ArticleYear
Prostate specific antigen: a prognostic marker of survival in good prognosis metastatic prostate cancer? (EORTC 30892).
    European urology, 2003, Volume: 44, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Bone Neoplasms; Cyprote

2003
Experience with flutamide in patients with advanced prostatic cancer without prior endocrine therapy.
    Cancer, 1984, Aug-15, Volume: 54, Issue:4

    Topics: Acid Phosphatase; Adenocarcinoma; Adult; Aged; Anilides; Bone Neoplasms; Clinical Trials as Topic; F

1984
A randomized phase II trial of flutamide vs chlormadinone acetate in previously untreated advanced prostatic cancer. The Japan Flutamide Study Group.
    Japanese journal of clinical oncology, 1993, Volume: 23, Issue:3

    Topics: Aged; Aged, 80 and over; Bone Neoplasms; Chlormadinone Acetate; Confidence Intervals; Double-Blind M

1993
Bilateral orchiectomy with or without flutamide for metastatic prostate cancer.
    The New England journal of medicine, 1998, Oct-08, Volume: 339, Issue:15

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Bone Neoplasms; Combined Modal

1998