flutamide and Pain
flutamide has been researched along with Pain in 10 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Five hundred forty-six patients with advanced loco-regional (M0) or distant metastatic (M1) prostatic carcinoma treated with flutamide combined with either orchiectomy or LHRH analogues were included in this analysis." | 5.08 | PSA evolution: a prognostic factor during treatment of advanced prostatic carcinoma with total androgen blockade. Data from a Belgian multicentric study of 546 patients. ( Casselman, J; Derde, MP; Kaufman, L; Mattelaer, J; Oosterlinck, W; Van Velthoven, R, 1997) |
| " Cross-sectional analyses (corrected for multiple testing) identified statistically significant differences that favored orchiectomy plus placebo for two of the five primary QOL parameters as follows: patients receiving flutamide reported more diarrhea at 3 months (P = ." | 5.08 | Quality of life in advanced prostate cancer: results of a randomized therapeutic trial. ( Blumenstein, BA; Crawford, ED; Eisenberger, M; Higgins, B; Lovato, LC; Meyskens, FL; Moinpour, CM; Savage, MJ; Skeel, R; Troxel, A; Veith, RW; Yee, M, 1998) |
| "To better define the involvement of gonadal hormones in the sex differences observed in experimental visceral pain, we administered antagonists of estrogen receptors (ICI 182,780 [ICI]) or androgen receptors (Flutamide [FLU]) to adult male and female rats suffering from artificial ureteral calculosis." | 3.77 | Sex differences in the analgesic effects of ICI 182,780 and Flutamide on ureteral calculosis in rats. ( Affaitati, G; Aloisi, AM; Aurilio, C; Ceccarelli, I; Danielli, B; Fiorenzani, P; Giamberardino, MA; Pace, MC; Passavanti, MB; Rossi, C; Sorda, G, 2011) |
| "Post-treatment prostate biopsy side-effects were evaluated in patients with locally advanced prostate cancer on endocrine therapy alone or combined with radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial." | 2.76 | Side-effects of post-treatment biopsies in prostate cancer patients treated with endocrine therapy alone or combined with radical radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial. ( Ahlgren, G; Angelsen, A; Solberg, A; Tasdemir, I; Widmark, A, 2011) |
| "Fourty-eight patients with stage D2 prostate cancer, initially treated with endocrine therapy at the University of Tokyo between 1981 and 1990, were followed up and analysed." | 1.29 | [Objective and subjective response in stage D2 prostate cancer patients with cancer pain]. ( Aso, Y; Higashihara, E; Hirasawa, K; Homma, Y; Kasuya, Y; Kawabe, K; Tanaka, Y; Yoshida, M, 1994) |
Research
Studies (10)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Uemura, H | 1 |
| Kobayashi, K | 1 |
| Yokomizo, A | 1 |
| Hinotsu, S | 1 |
| Horie, S | 1 |
| Kakehi, Y | 1 |
| Nonomura, N | 1 |
| Ogawa, O | 1 |
| Oya, M | 1 |
| Suzuki, K | 1 |
| Saito, A | 1 |
| Asakawa, K | 1 |
| Uno, S | 1 |
| Naito, S | 1 |
| Fanton, LE | 1 |
| Macedo, CG | 1 |
| Torres-Chávez, KE | 1 |
| Fischer, L | 1 |
| Tambeli, CH | 1 |
| Affaitati, G | 1 |
| Ceccarelli, I | 1 |
| Fiorenzani, P | 1 |
| Rossi, C | 1 |
| Pace, MC | 1 |
| Passavanti, MB | 1 |
| Aurilio, C | 1 |
| Sorda, G | 1 |
| Danielli, B | 1 |
| Giamberardino, MA | 1 |
| Aloisi, AM | 1 |
| Solberg, A | 1 |
| Widmark, A | 1 |
| Tasdemir, I | 1 |
| Ahlgren, G | 1 |
| Angelsen, A | 1 |
| Yoshida, M | 1 |
| Hirasawa, K | 1 |
| Kasuya, Y | 1 |
| Tanaka, Y | 1 |
| Homma, Y | 1 |
| Higashihara, E | 1 |
| Kawabe, K | 1 |
| Aso, Y | 1 |
| da Silva, FC | 1 |
| Oosterlinck, W | 1 |
| Mattelaer, J | 1 |
| Casselman, J | 1 |
| Van Velthoven, R | 1 |
| Derde, MP | 1 |
| Kaufman, L | 1 |
| Moinpour, CM | 1 |
| Savage, MJ | 1 |
| Troxel, A | 1 |
| Lovato, LC | 1 |
| Eisenberger, M | 1 |
| Veith, RW | 1 |
| Higgins, B | 1 |
| Skeel, R | 1 |
| Yee, M | 1 |
| Blumenstein, BA | 1 |
| Crawford, ED | 1 |
| Meyskens, FL | 1 |
| Baum, N | 1 |
| Brown, P | 1 |
| Labrie, F | 1 |
| Dupont, A | 1 |
| Cusan, L | 1 |
| Giguere, M | 1 |
| Bergeron, N | 1 |
| Borsanyi, JP | 1 |
| Lacourciere, Y | 1 |
| Belanger, A | 1 |
| Emond, J | 1 |
| Monfette, G | 1 |
Trials
5 trials available for flutamide and Pain
| Article | Year |
|---|---|
Side-effects of post-treatment biopsies in prostate cancer patients treated with endocrine therapy alone or combined with radical radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Biopsy; Combined Mod | 2011 |
Quality of life in prostatic carcinoma.
Topics: Activities of Daily Living; Flutamide; Goserelin; Humans; Interpersonal Relations; Male; Orchiectomy | 1993 |
PSA evolution: a prognostic factor during treatment of advanced prostatic carcinoma with total androgen blockade. Data from a Belgian multicentric study of 546 patients.
Topics: Aged; Analysis of Variance; Androgen Antagonists; Antineoplastic Agents, Hormonal; Belgium; Carcinom | 1997 |
Quality of life in advanced prostate cancer: results of a randomized therapeutic trial.
Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cross-Section | 1998 |
Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in previously untreated patients with clinical stage D2 prostate cancer: today's therapy of choice.
Topics: Aged; Anilides; Clinical Trials as Topic; Combined Modality Therapy; Flutamide; Gonadotropin-Releasi | 1988 |
Other Studies
5 other studies available for flutamide and Pain
| Article | Year |
|---|---|
Health-related quality of life with enzalutamide versus flutamide in castration-resistant prostate cancer from the AFTERCAB study.
Topics: Androgen Antagonists; Androgens; Benzamides; Disease-Free Survival; Flutamide; Humans; Male; Nitrile | 2022 |
Activational action of testosterone on androgen receptors protects males preventing temporomandibular joint pain.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Dutasteride; Estradiol; Estrogen Recept | 2017 |
Sex differences in the analgesic effects of ICI 182,780 and Flutamide on ureteral calculosis in rats.
Topics: Analgesics; Analysis of Variance; Animals; Estradiol; Female; Flutamide; Fulvestrant; Male; Pain; Ra | 2011 |
[Objective and subjective response in stage D2 prostate cancer patients with cancer pain].
Topics: Aged; Aged, 80 and over; Bone Neoplasms; Diethylstilbestrol; Flutamide; Follow-Up Studies; Humans; M | 1994 |
Carcinoma of the prostate. Treating disease that has metastasized.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dissemina | 1990 |