Page last updated: 2024-10-27

flutamide and Pain

flutamide has been researched along with Pain in 10 studies

Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Five hundred forty-six patients with advanced loco-regional (M0) or distant metastatic (M1) prostatic carcinoma treated with flutamide combined with either orchiectomy or LHRH analogues were included in this analysis."5.08PSA evolution: a prognostic factor during treatment of advanced prostatic carcinoma with total androgen blockade. Data from a Belgian multicentric study of 546 patients. ( Casselman, J; Derde, MP; Kaufman, L; Mattelaer, J; Oosterlinck, W; Van Velthoven, R, 1997)
" Cross-sectional analyses (corrected for multiple testing) identified statistically significant differences that favored orchiectomy plus placebo for two of the five primary QOL parameters as follows: patients receiving flutamide reported more diarrhea at 3 months (P = ."5.08Quality of life in advanced prostate cancer: results of a randomized therapeutic trial. ( Blumenstein, BA; Crawford, ED; Eisenberger, M; Higgins, B; Lovato, LC; Meyskens, FL; Moinpour, CM; Savage, MJ; Skeel, R; Troxel, A; Veith, RW; Yee, M, 1998)
"To better define the involvement of gonadal hormones in the sex differences observed in experimental visceral pain, we administered antagonists of estrogen receptors (ICI 182,780 [ICI]) or androgen receptors (Flutamide [FLU]) to adult male and female rats suffering from artificial ureteral calculosis."3.77Sex differences in the analgesic effects of ICI 182,780 and Flutamide on ureteral calculosis in rats. ( Affaitati, G; Aloisi, AM; Aurilio, C; Ceccarelli, I; Danielli, B; Fiorenzani, P; Giamberardino, MA; Pace, MC; Passavanti, MB; Rossi, C; Sorda, G, 2011)
"Post-treatment prostate biopsy side-effects were evaluated in patients with locally advanced prostate cancer on endocrine therapy alone or combined with radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial."2.76Side-effects of post-treatment biopsies in prostate cancer patients treated with endocrine therapy alone or combined with radical radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial. ( Ahlgren, G; Angelsen, A; Solberg, A; Tasdemir, I; Widmark, A, 2011)
"Fourty-eight patients with stage D2 prostate cancer, initially treated with endocrine therapy at the University of Tokyo between 1981 and 1990, were followed up and analysed."1.29[Objective and subjective response in stage D2 prostate cancer patients with cancer pain]. ( Aso, Y; Higashihara, E; Hirasawa, K; Homma, Y; Kasuya, Y; Kawabe, K; Tanaka, Y; Yoshida, M, 1994)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's5 (50.00)18.2507
2000's0 (0.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Uemura, H1
Kobayashi, K1
Yokomizo, A1
Hinotsu, S1
Horie, S1
Kakehi, Y1
Nonomura, N1
Ogawa, O1
Oya, M1
Suzuki, K1
Saito, A1
Asakawa, K1
Uno, S1
Naito, S1
Fanton, LE1
Macedo, CG1
Torres-Chávez, KE1
Fischer, L1
Tambeli, CH1
Affaitati, G1
Ceccarelli, I1
Fiorenzani, P1
Rossi, C1
Pace, MC1
Passavanti, MB1
Aurilio, C1
Sorda, G1
Danielli, B1
Giamberardino, MA1
Aloisi, AM1
Solberg, A1
Widmark, A1
Tasdemir, I1
Ahlgren, G1
Angelsen, A1
Yoshida, M1
Hirasawa, K1
Kasuya, Y1
Tanaka, Y1
Homma, Y1
Higashihara, E1
Kawabe, K1
Aso, Y1
da Silva, FC1
Oosterlinck, W1
Mattelaer, J1
Casselman, J1
Van Velthoven, R1
Derde, MP1
Kaufman, L1
Moinpour, CM1
Savage, MJ1
Troxel, A1
Lovato, LC1
Eisenberger, M1
Veith, RW1
Higgins, B1
Skeel, R1
Yee, M1
Blumenstein, BA1
Crawford, ED1
Meyskens, FL1
Baum, N1
Brown, P1
Labrie, F1
Dupont, A1
Cusan, L1
Giguere, M1
Bergeron, N1
Borsanyi, JP1
Lacourciere, Y1
Belanger, A1
Emond, J1
Monfette, G1

Trials

5 trials available for flutamide and Pain

ArticleYear
Side-effects of post-treatment biopsies in prostate cancer patients treated with endocrine therapy alone or combined with radical radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial.
    Scandinavian journal of urology and nephrology, 2011, Volume: 45, Issue:4

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Biopsy; Combined Mod

2011
Quality of life in prostatic carcinoma.
    European urology, 1993, Volume: 24 Suppl 2

    Topics: Activities of Daily Living; Flutamide; Goserelin; Humans; Interpersonal Relations; Male; Orchiectomy

1993
PSA evolution: a prognostic factor during treatment of advanced prostatic carcinoma with total androgen blockade. Data from a Belgian multicentric study of 546 patients.
    Acta urologica Belgica, 1997, Volume: 65, Issue:3

    Topics: Aged; Analysis of Variance; Androgen Antagonists; Antineoplastic Agents, Hormonal; Belgium; Carcinom

1997
Quality of life in advanced prostate cancer: results of a randomized therapeutic trial.
    Journal of the National Cancer Institute, 1998, Oct-21, Volume: 90, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cross-Section

1998
Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in previously untreated patients with clinical stage D2 prostate cancer: today's therapy of choice.
    Journal of steroid biochemistry, 1988, Volume: 30, Issue:1-6

    Topics: Aged; Anilides; Clinical Trials as Topic; Combined Modality Therapy; Flutamide; Gonadotropin-Releasi

1988

Other Studies

5 other studies available for flutamide and Pain

ArticleYear
Health-related quality of life with enzalutamide versus flutamide in castration-resistant prostate cancer from the AFTERCAB study.
    International journal of clinical oncology, 2022, Volume: 27, Issue:10

    Topics: Androgen Antagonists; Androgens; Benzamides; Disease-Free Survival; Flutamide; Humans; Male; Nitrile

2022
Activational action of testosterone on androgen receptors protects males preventing temporomandibular joint pain.
    Pharmacology, biochemistry, and behavior, 2017, Volume: 152

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Dutasteride; Estradiol; Estrogen Recept

2017
Sex differences in the analgesic effects of ICI 182,780 and Flutamide on ureteral calculosis in rats.
    Hormones and behavior, 2011, Volume: 59, Issue:1

    Topics: Analgesics; Analysis of Variance; Animals; Estradiol; Female; Flutamide; Fulvestrant; Male; Pain; Ra

2011
[Objective and subjective response in stage D2 prostate cancer patients with cancer pain].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1994, Volume: 85, Issue:3

    Topics: Aged; Aged, 80 and over; Bone Neoplasms; Diethylstilbestrol; Flutamide; Follow-Up Studies; Humans; M

1994
Carcinoma of the prostate. Treating disease that has metastasized.
    Postgraduate medicine, 1990, Nov-01, Volume: 88, Issue:6

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dissemina

1990