flutamide has been researched along with Necrosis in 3 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three of 34 patients treated with a TAS regimen incorporating flutamide developed significant hepatic abnormalities: elevated transaminases [2] and fatal hepatic necrosis [1]." | 7.69 | Flutamide-induced liver toxicity including fatal hepatic necrosis. ( Chen, A; Crownover, RL; Fu, KK; Holland, J; Krieg, R; Roach, M; Young, BK, 1996) |
| "Three of 34 patients treated with a TAS regimen incorporating flutamide developed significant hepatic abnormalities: elevated transaminases [2] and fatal hepatic necrosis [1]." | 3.69 | Flutamide-induced liver toxicity including fatal hepatic necrosis. ( Chen, A; Crownover, RL; Fu, KK; Holland, J; Krieg, R; Roach, M; Young, BK, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kashimshetty, R | 1 |
| Desai, VG | 1 |
| Kale, VM | 1 |
| Lee, T | 1 |
| Moland, CL | 1 |
| Branham, WS | 1 |
| New, LS | 1 |
| Chan, EC | 1 |
| Younis, H | 1 |
| Boelsterli, UA | 1 |
| Crownover, RL | 1 |
| Holland, J | 1 |
| Chen, A | 1 |
| Krieg, R | 1 |
| Young, BK | 1 |
| Roach, M | 1 |
| Fu, KK | 1 |
| Gómez Veiga, F | 1 |
| Lorenzo Patiño, MJ | 1 |
| Díaz Bermúdez, J | 1 |
| Duarte Novo, J | 1 |
| Alvarez Castelo, L | 1 |
| Chantada Abal, V | 1 |
| Sánchez Rodríguez, J | 1 |
| González Martín, M | 1 |
3 other studies available for flutamide and Necrosis
| Article | Year |
|---|---|
Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity.
Topics: Alanine Transaminase; Androgen Antagonists; Anilides; Animals; Apoptosis; Dose-Response Relationship | 2009 |
Flutamide-induced liver toxicity including fatal hepatic necrosis.
Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flutamide; Humans; Live | 1996 |
[Effect of complete androgen block before radical prostatectomy for cancer of the prostate].
Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; | 1997 |