Page last updated: 2024-10-27

flutamide and Necrosis

flutamide has been researched along with Necrosis in 3 studies

Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Three of 34 patients treated with a TAS regimen incorporating flutamide developed significant hepatic abnormalities: elevated transaminases [2] and fatal hepatic necrosis [1]."7.69Flutamide-induced liver toxicity including fatal hepatic necrosis. ( Chen, A; Crownover, RL; Fu, KK; Holland, J; Krieg, R; Roach, M; Young, BK, 1996)
"Three of 34 patients treated with a TAS regimen incorporating flutamide developed significant hepatic abnormalities: elevated transaminases [2] and fatal hepatic necrosis [1]."3.69Flutamide-induced liver toxicity including fatal hepatic necrosis. ( Chen, A; Crownover, RL; Fu, KK; Holland, J; Krieg, R; Roach, M; Young, BK, 1996)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kashimshetty, R1
Desai, VG1
Kale, VM1
Lee, T1
Moland, CL1
Branham, WS1
New, LS1
Chan, EC1
Younis, H1
Boelsterli, UA1
Crownover, RL1
Holland, J1
Chen, A1
Krieg, R1
Young, BK1
Roach, M1
Fu, KK1
Gómez Veiga, F1
Lorenzo Patiño, MJ1
Díaz Bermúdez, J1
Duarte Novo, J1
Alvarez Castelo, L1
Chantada Abal, V1
Sánchez Rodríguez, J1
González Martín, M1

Other Studies

3 other studies available for flutamide and Necrosis

ArticleYear
Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity.
    Toxicology and applied pharmacology, 2009, Jul-15, Volume: 238, Issue:2

    Topics: Alanine Transaminase; Androgen Antagonists; Anilides; Animals; Apoptosis; Dose-Response Relationship

2009
Flutamide-induced liver toxicity including fatal hepatic necrosis.
    International journal of radiation oncology, biology, physics, 1996, Mar-01, Volume: 34, Issue:4

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flutamide; Humans; Live

1996
[Effect of complete androgen block before radical prostatectomy for cancer of the prostate].
    Archivos espanoles de urologia, 1997, Volume: 50, Issue:4

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant;

1997