flutamide has been researched along with Methemoglobinemia in 5 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether the nonsteroidal antiandrogenic drug flutamide is a clinically relevant inducer of methemoglobinemia in patients with prostatic cancer." | 9.09 | Lack of methemoglobinemia with flutamide. ( Becker, H; Donn, F; Schmoldt, A; Schulz, M, 2001) |
| "The authors report a case of clinical methemoglobinemia occurring one year after a patient began receiving flutamide 750 mg/d for prostate cancer with bone metastasis." | 7.68 | Flutamide-induced methemoglobinemia. ( Chareyre, S; Delmas, PD; Gozzo, I; Schott, AM; Vial, T, 1991) |
| "To determine whether the nonsteroidal antiandrogenic drug flutamide is a clinically relevant inducer of methemoglobinemia in patients with prostatic cancer." | 5.09 | Lack of methemoglobinemia with flutamide. ( Becker, H; Donn, F; Schmoldt, A; Schulz, M, 2001) |
| "The authors report a case of clinical methemoglobinemia occurring one year after a patient began receiving flutamide 750 mg/d for prostate cancer with bone metastasis." | 3.68 | Flutamide-induced methemoglobinemia. ( Chareyre, S; Delmas, PD; Gozzo, I; Schott, AM; Vial, T, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jackson, SH | 1 |
| Barker, SJ | 1 |
| Kouides, PA | 1 |
| Abboud, CN | 1 |
| Fairbanks, VF | 1 |
| Khan, AM | 1 |
| Singh, NT | 1 |
| Bilgrami, S | 1 |
| Schulz, M | 1 |
| Schmoldt, A | 1 |
| Donn, F | 1 |
| Becker, H | 1 |
| Schott, AM | 1 |
| Vial, T | 1 |
| Gozzo, I | 1 |
| Chareyre, S | 1 |
| Delmas, PD | 1 |
1 review available for flutamide and Methemoglobinemia
| Article | Year |
|---|---|
Flutamide induced methemoglobinemia.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Flutamide; Humans; Male; Methemoglobinemia | 1997 |
1 trial available for flutamide and Methemoglobinemia
| Article | Year |
|---|---|
Lack of methemoglobinemia with flutamide.
Topics: Aged; Antineoplastic Agents, Hormonal; Flutamide; Humans; Male; Methemoglobin; Methemoglobinemia; Mi | 2001 |
3 other studies available for flutamide and Methemoglobinemia
| Article | Year |
|---|---|
Methemoglobinemia in a patient receiving flutamide.
Topics: Aged; Cardiopulmonary Bypass; Flutamide; Humans; Male; Methemoglobinemia; Prostatic Neoplasms | 1995 |
Flutamide-induced cyanosis refractory to methylene blue therapy.
Topics: Aged; Antineoplastic Agents, Hormonal; Cyanosis; Flutamide; Humans; Male; Methemoglobinemia; Methyle | 1996 |
Flutamide-induced methemoglobinemia.
Topics: Aged; Aged, 80 and over; Flutamide; Humans; Male; Methemoglobinemia; Prostatic Neoplasms | 1991 |