flutamide has been researched along with Melanoma in 2 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because preclinical studies suggest an interaction between androgens and the immune system, we used a murine model to determine whether androgen blockade with flutamide might enhance the immunogenicity of an irradiated melanoma cell vaccine." | 3.72 | Androgen blockade enhances response to melanoma vaccine. ( Gupta, RK; Hsueh, EC; Lefor, A; Morton, DL; Reyzin, G; Ye, W, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsueh, EC | 1 |
| Gupta, RK | 1 |
| Lefor, A | 1 |
| Reyzin, G | 1 |
| Ye, W | 1 |
| Morton, DL | 1 |
| Morvillo, V | 1 |
| Luthy, IA | 1 |
| Bravo, AI | 1 |
| Capurro, MI | 1 |
| Donaldson, M | 1 |
| Quintans, C | 1 |
| Calandra, RS | 1 |
| Mordoh, J | 1 |
2 other studies available for flutamide and Melanoma
| Article | Year |
|---|---|
Androgen blockade enhances response to melanoma vaccine.
Topics: Androgen Antagonists; Animals; Cancer Vaccines; Drug Synergism; Flutamide; Immunotherapy, Active; In | 2003 |
Atypical androgen receptor in the human melanoma cell line IIB-MEL-J.
Topics: Androgen Antagonists; Animals; Antibodies, Monoclonal; Antineoplastic Agents, Hormonal; Binding, Com | 1995 |