Page last updated: 2024-10-27

flutamide and Melanoma

flutamide has been researched along with Melanoma in 2 studies

Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"Because preclinical studies suggest an interaction between androgens and the immune system, we used a murine model to determine whether androgen blockade with flutamide might enhance the immunogenicity of an irradiated melanoma cell vaccine."3.72Androgen blockade enhances response to melanoma vaccine. ( Gupta, RK; Hsueh, EC; Lefor, A; Morton, DL; Reyzin, G; Ye, W, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hsueh, EC1
Gupta, RK1
Lefor, A1
Reyzin, G1
Ye, W1
Morton, DL1
Morvillo, V1
Luthy, IA1
Bravo, AI1
Capurro, MI1
Donaldson, M1
Quintans, C1
Calandra, RS1
Mordoh, J1

Other Studies

2 other studies available for flutamide and Melanoma

ArticleYear
Androgen blockade enhances response to melanoma vaccine.
    The Journal of surgical research, 2003, Volume: 110, Issue:2

    Topics: Androgen Antagonists; Animals; Cancer Vaccines; Drug Synergism; Flutamide; Immunotherapy, Active; In

2003
Atypical androgen receptor in the human melanoma cell line IIB-MEL-J.
    Pigment cell research, 1995, Volume: 8, Issue:3

    Topics: Androgen Antagonists; Animals; Antibodies, Monoclonal; Antineoplastic Agents, Hormonal; Binding, Com

1995