flutamide has been researched along with Inflammation in 7 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "this study aims to explore the effect of androgen receptor (AR) blockade by flutamide on some renal pathologic changes such as inflammation, apoptosis, and fibrosis in male rats." | 8.31 | Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats. ( Abd Elaziz, AI; Allam, S; Amin, MM; Doghish, AS; El Shahat, RM; Elkady, MA; Elsakka, EGE; Hashish, AA; Ismail, A; Mohammed, OA; Mokhlis, HA; Sayed, SM; Yehia, AM, 2023) |
| "We hypothesized that administration of androgen receptors antagonist flutamide following trauma-hemorrhage (T-H) in metestrus females will maintain immune function and reduce remote organ damage under those conditions." | 7.73 | Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females. ( Chaudry, IH; Choudhry, MA; Hildebrand, F; Hubbard, WJ; Pape, HC; Thobe, BM, 2006) |
| "this study aims to explore the effect of androgen receptor (AR) blockade by flutamide on some renal pathologic changes such as inflammation, apoptosis, and fibrosis in male rats." | 4.31 | Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats. ( Abd Elaziz, AI; Allam, S; Amin, MM; Doghish, AS; El Shahat, RM; Elkady, MA; Elsakka, EGE; Hashish, AA; Ismail, A; Mohammed, OA; Mokhlis, HA; Sayed, SM; Yehia, AM, 2023) |
| "We hypothesized that administration of androgen receptors antagonist flutamide following trauma-hemorrhage (T-H) in metestrus females will maintain immune function and reduce remote organ damage under those conditions." | 3.73 | Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females. ( Chaudry, IH; Choudhry, MA; Hildebrand, F; Hubbard, WJ; Pape, HC; Thobe, BM, 2006) |
| "Cholestasis is one of the major causes of drug-induced liver injury (DILI), which can result in withdrawal of approved drugs from the market." | 1.46 | Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics. ( Honda, H; Ito, Y; Kawamoto, T; Morita, O, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Allam, S | 1 |
| Elsakka, EGE | 1 |
| Ismail, A | 1 |
| Doghish, AS | 1 |
| Yehia, AM | 1 |
| Elkady, MA | 1 |
| Mokhlis, HA | 1 |
| Sayed, SM | 1 |
| Abd Elaziz, AI | 1 |
| Hashish, AA | 1 |
| Amin, MM | 1 |
| El Shahat, RM | 1 |
| Mohammed, OA | 1 |
| Kawamoto, T | 1 |
| Ito, Y | 1 |
| Morita, O | 1 |
| Honda, H | 1 |
| Son, BK | 1 |
| Kojima, T | 1 |
| Ogawa, S | 1 |
| Akishita, M | 1 |
| Fijak, M | 1 |
| Damm, LJ | 1 |
| Wenzel, JP | 1 |
| Aslani, F | 1 |
| Walecki, M | 1 |
| Wahle, E | 1 |
| Eisel, F | 1 |
| Bhushan, S | 1 |
| Hackstein, H | 1 |
| Baal, N | 1 |
| Schuler, G | 1 |
| Konrad, L | 1 |
| Rafiq, A | 1 |
| O'Hara, L | 1 |
| Smith, LB | 1 |
| Meinhardt, A | 1 |
| Wang, SY | 1 |
| Freeman, MR | 1 |
| Sathish, V | 1 |
| Thompson, MA | 1 |
| Pabelick, CM | 1 |
| Prakash, YS | 1 |
| Hildebrand, F | 1 |
| Hubbard, WJ | 1 |
| Choudhry, MA | 1 |
| Thobe, BM | 1 |
| Pape, HC | 1 |
| Chaudry, IH | 1 |
7 other studies available for flutamide and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats.
Topics: Androgens; Animals; Apoptosis; Caspases; Fibrosis; Flutamide; Inflammation; Interleukin-6; Kidney Di | 2023 |
Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics.
Topics: Administration, Oral; Animals; Chlorpromazine; Cholestasis; Cholesterol; Cyclosporine; Diclofenac; D | 2017 |
Testosterone inhibits aneurysm formation and vascular inflammation in male mice.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure | 2019 |
Influence of Testosterone on Inflammatory Response in Testicular Cells and Expression of Transcription Factor Foxp3 in T Cells.
Topics: Androgen Antagonists; Animals; Cell Differentiation; Cells, Cultured; Chemokine CCL2; Culture Media, | 2015 |
Sex Steroids Influence Brain-Derived Neurotropic Factor Secretion From Human Airway Smooth Muscle Cells.
Topics: Airway Remodeling; Asthma; Brain-Derived Neurotrophic Factor; Estradiol; Estrogens; Female; Flutamid | 2016 |
Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females.
Topics: Animals; Chemokine CCL2; Cytokines; Enzyme Activation; Estradiol; Female; Flow Cytometry; Flutamide; | 2006 |