flutamide has been researched along with Hyperplasia in 4 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An important step in the safety assessment of chemicals for humans is to determine the no observed adverse effect level (NOAEL) in toxicity studies conducted in animal models." | 1.35 | Standard and molecular NOAELs for rat testicular toxicity induced by flutamide. ( Bars, R; Friry-Santini, C; Rouquié, D; Schorsch, F; Tinwell, H, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rouquié, D | 2 |
| Friry-Santini, C | 2 |
| Schorsch, F | 1 |
| Tinwell, H | 2 |
| Bars, R | 2 |
| Kennel, P | 1 |
| Benahmed, M | 1 |
| Sourla, A | 1 |
| Richard, V | 1 |
| Labrie, F | 1 |
| Labrie, C | 1 |
| Juniewicz, PE | 1 |
| Barbolt, TA | 1 |
| Egy, MA | 1 |
| Frenette, G | 1 |
| Dube, JY | 1 |
| Tremblay, RR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of DHEA on Skin Aging - Placebo-Controlled and Randomized Phase III Study in Postmenopausal Women.[NCT00248989] | Phase 3 | 150 participants (Actual) | Interventional | 2004-11-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for flutamide and Hyperplasia
| Article | Year |
|---|---|
Standard and molecular NOAELs for rat testicular toxicity induced by flutamide.
Topics: Androgen Antagonists; Animals; Cell Death; Cell Proliferation; Data Interpretation, Statistical; Flu | 2009 |
Correlation between protein accumulation profiles and conventional toxicological findings using a model antiandrogenic compound, flutamide.
Topics: Androgen Antagonists; Animals; Biomarkers; Dose-Response Relationship, Drug; Electrophoresis, Gel, T | 2007 |
Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin.
Topics: Administration, Cutaneous; Androgen Antagonists; Animals; Benzopyrans; Dehydroepiandrosterone; Estro | 2000 |
Effects of androgen and antiandrogen treatment on canine prostatic arginine esterase.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Androstane-3,17-diol; Androstenes; An | 1990 |