flutamide has been researched along with Hypercapnia in 2 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To test this hypothesis, we evaluated ventilation (V̇ E), metabolic rate and body temperature (Tb) under normoxia/normocapnia, hypercapnia and hypoxia in orchiectomized (ORX), ORX with testosterone replacement (ORX + T) or flutamide (FL, androgen receptor blocker)-treated rats." | 3.96 | The role of testosterone in the respiratory and thermal responses to hypoxia and hypercapnia in rats. ( Bícego, KC; Gargaglioni, LH; Marques, DA; Patrone, LGA; Scarpellini, CS; Szawka, RE, 2020) |
| "As sleep apnea is more prevalent in men and testosterone has known effects on sleep apnea and chemosensitivity, reduction of androgen activity may influence sleep-disordered breathing and respiratory control." | 1.28 | Androgen blockade does not affect sleep-disordered breathing or chemosensitivity in men with obstructive sleep apnea. ( Berthon-Jones, M; Grunstein, RR; Handelsman, DJ; Stewart, DA; Sullivan, CE, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marques, DA | 1 |
| Patrone, LGA | 1 |
| Scarpellini, CS | 1 |
| Bícego, KC | 1 |
| Szawka, RE | 1 |
| Gargaglioni, LH | 1 |
| Stewart, DA | 1 |
| Grunstein, RR | 1 |
| Berthon-Jones, M | 1 |
| Handelsman, DJ | 1 |
| Sullivan, CE | 1 |
2 other studies available for flutamide and Hypercapnia
| Article | Year |
|---|---|
The role of testosterone in the respiratory and thermal responses to hypoxia and hypercapnia in rats.
Topics: Androgen Receptor Antagonists; Animals; Body Temperature Regulation; Carotid Body; Flutamide; Hyperc | 2020 |
Androgen blockade does not affect sleep-disordered breathing or chemosensitivity in men with obstructive sleep apnea.
Topics: Adult; Aged; Androgens; Flutamide; Humans; Hypercapnia; Hypoxia; Male; Middle Aged; Respiration; Sle | 1992 |