flutamide has been researched along with Huntington Disease in 1 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this work is to know the effect of flutamide and a novel synthetic steroid 3β-p-Iodobenzoyloxypregnan-4,16- diene-6,20-dione (IBP) on the levels of dopamine, 5-HIAA (5-hydroxyindole acetic acid), and some oxidative stress markers in animal model with Huntington disease." | 3.80 | Effect of two antiandrogens as protectors of prostate and brain in a Huntington's animal model. ( Bratoeff, E; Brizuela, NO; Cruz, EG; Garcia, EH; Guzman, DC; Mejia, GB; Olguin, HJ; Riveros, AC, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guzman, DC | 1 |
| Bratoeff, E | 1 |
| Riveros, AC | 1 |
| Brizuela, NO | 1 |
| Mejia, GB | 1 |
| Garcia, EH | 1 |
| Olguin, HJ | 1 |
| Cruz, EG | 1 |
1 other study available for flutamide and Huntington Disease
| Article | Year |
|---|---|
Effect of two antiandrogens as protectors of prostate and brain in a Huntington's animal model.
Topics: Androgen Antagonists; Animals; Biomarkers; Brain; Dopamine; Dydrogesterone; Flutamide; Huntington Di | 2014 |