flutamide has been researched along with Hirsutism in 88 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Hirsutism: A condition observed in WOMEN and CHILDREN when there is excess coarse body hair of an adult male distribution pattern, such as facial and chest areas. It is the result of elevated ANDROGENS from the OVARIES, the ADRENAL GLANDS, or exogenous sources. The concept does not include HYPERTRICHOSIS, which is an androgen-independent excessive hair growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the long-term safety and tolerability of flutamide therapy for hirsutism." | 9.14 | Long-term safety and tolerability of flutamide for the treatment of hirsutism. ( Balasch, J; Castelo-Branco, C; Gómez, O; Moyano, D, 2009) |
| " Twenty-nine women with hirsutism as a consequence of PCOS or idiopathic hirsutism were randomly assigned to receive 250 mg/day flutamide alone or 100 mg/day spironolactone plus a combination tablet of 2 mg CPA/35 microg EE, for 6 months." | 9.13 | Comparison of the clinical efficacy of flutamide and spironolactone plus ethinyloestradiol/cyproterone acetate in the treatment of hirsutism: a randomised controlled study. ( Aral, Y; Bavbek, N; Culha, C; Demirbas, B; Güler, S; Karakurt, F; Sahin, I; Serter, R, 2008) |
| " All flutamide doses induced a significant decrease in hirsutism, acne, and seborrhea scores after 12 months compared with placebo without differences among dose levels." | 9.12 | Long-term efficacy and tolerability of flutamide combined with oral contraception in moderate to severe hirsutism: a 12-month, double-blind, parallel clinical trial. ( Alcañiz, J; Calaf, J; Callejo, J; Escobar-Jiménez, F; Espinós, JJ; Fortuny, A; López, E; Millet, A; Torres, E; Vidal, O, 2007) |
| "To compare the effectiveness of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism (IH)." | 9.11 | Comparison of the clinical efficacy of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism: a randomized controlled study. ( Inal, MM; Taner, CE; Yildirim, Y, 2005) |
| "To assess the effectiveness of flutamide in the treatment of hirsutism, used as monotherapy or combined with oral contraceptives (OC)." | 9.11 | [Effectiveness of flutamide alone or combined with oral contraceptives in the treatment of hirsutism in women]. ( Aravena, L; Devoto, E, 2004) |
| "To compare the clinical, hormonal, biochemical and hemotological effects of flutamide versus flutamide plus an oral contraceptive (OC) in the treatment of hirsutism." | 9.10 | Comparison of the clinical efficacy and safety of flutamide versus flutamide plus an oral contraceptive in the treatment of hirsutism. ( Başogul, O; Inal, M; Ispahi, C; Karanfil, C; Onoglu, A; Taner, C; Tinar, S, 2002) |
| "To compare the long-term (1 year) effects of flutamide (250 mg/d) and finasteride (5 mg/d) for the treatment of hirsutism in women." | 9.09 | A prospective, randomized trial comparing flutamide (250 mg/d) and finasteride (5 mg/d) in the treatment of hirsutism. ( Bayram, F; Güven, M; Müderris, II, 2000) |
| "The objective of this prospective randomized study was to evaluate and compare the hormonal and clinical effects of long-acting gonadotropin-releasing hormone (GnRH) agonist and a combination of GnRH agonist with combined oral contraceptive (COC) or flutamide in women with polycystic ovary syndrome (PCOS)." | 9.09 | Hormonal and clinical effects of GnRH agonist alone, or in combination with a combined oral contraceptive or flutamide in women with severe hirsutism. ( Caruso, A; De Leo, V; Fulghesu, AM; la Marca, A; Morgante, G; Pasqui, L; Talluri, B; Torricelli, M, 2000) |
| "To evaluate the safety and efficacy of a low dose of flutamide (125 mg/day) in maintaining the clinical results already obtained using a higher dose (250 mg/day), in women suffering from hirsutism." | 9.09 | Low-dose flutamide (125 mg/day) as maintenance therapy in the treatment of hirsutism. ( Bagnoli, A; Colombo, FM; Gualerzi, B; Mancini, F; Paradisi, R; Porcu, E; Ravaioli, B; Seracchioli, R; Venturoli, S; Vianello, F, 2001) |
| "To compare the effectiveness of finasteride and flutamide in the treatment of idiopathic hirsutism." | 9.09 | Comparison of finasteride and flutamide in the treatment of idiopathic hirsutism. ( Falsetti, L; Gambera, A, 1999) |
| "Flutamide has been used successfully in the treatment of hirsutism." | 9.09 | Treatment of hirsutism with lowest-dose flutamide (62.5 mg/day). ( Bayram, F; Güven, M; Müderris, II, 2000) |
| " Flutamide, a nonsteroidal antiandrogen, is known to be effective in reducing hirsutism in patients with ovarian hyperandrogenism." | 9.09 | Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in nonobese, adolescent girls: effect of flutamide. ( de Zegher, F; Ibáñez, L; Marcos, MV; Potau, N, 2000) |
| "To compare triptorelin, cyproterone acetate (CPA), and flutamide, in combination with an oral contraceptive, in the treatment of hirsutism." | 9.09 | Prospective randomized study comparing the long-acting gonadotropin-releasing hormone agonist triptorelin, flutamide, and cyproterone acetate, used in combination with an oral contraceptive, in the treatment of hirsutism. ( Balsa, J; Escobar-Morreale, HF; Pazos, F; Sancho, JM; Varela, C, 1999) |
| "To investigate insulin metabolism and its modifications induced by the administration of flutamide, a specific antiandrogen compound, in women with idiopathic hirsutism (IH) and in nonobese women with polycystic ovary syndrome (PCOS)." | 9.09 | Treatment with flutamide improves hyperinsulinemia in women with idiopathic hirsutism. ( Ajossa, S; Cagnacci, A; Guerriero, S; Melis, GB; Orrù, M; Paoletti, AM, 1999) |
| "To compare the effectiveness of finasteride and flutamide in the treatment of hirsutism in patients with polycystic ovary syndrome (PCOS) and with idiopathic hirsutism." | 9.09 | Comparison of finasteride versus flutamide in the treatment of hirsutism. ( Bugari, G; Falsetti, L; Gambera, A; Iacobello, C; Legrenzi, L, 1999) |
| "To compare objectively the efficacies of spironolactone (100 mg/day), flutamide (250 mg/day), and finasteride (5 mg/day) in the treatment of hirsutism, 40 hirsute women were randomly assigned to double blind treatments with 1 of these 3 drugs or placebo for 6 months." | 9.09 | Comparison of spironolactone, flutamide, and finasteride efficacy in the treatment of hirsutism: a randomized, double blind, placebo-controlled trial. ( Caputo, M; Castello, R; Misciali, C; Moghetti, P; Muggeo, M; Negri, C; Perrone, F; Tosi, F; Tosti, A, 2000) |
| "High doses of flutamide, which is the only antiandrogen that specifically blocks the androgen receptor, have recently been used with good clinical results in women with hirsutism." | 9.08 | Clinical efficacy and safety of low-dose flutamide alone and combined with an oral contraceptive for the treatment of idiopathic hirsutism. ( Cédrin, I; Dodin, S; Faure, N; Guy, J; Lemay, A; Méchain, C; Turcot-Lemay, L, 1995) |
| "To compare the effects of flutamide at 250 mg/d and 500 mg/d in the treatment of hirsutism." | 9.08 | A comparison between two doses of flutamide (250 mg/d and 500 mg/d) in the treatment of hirsutism. ( Bayram, F; Keleştimur, F; Müderris, II; Sahin, Y, 1997) |
| "To investigate the effects of low dose flutamide (250 mg/d) on hirsutism score and hormone levels in women with hirsutism." | 9.08 | The efficacy of 250 mg/day flutamide in the treatment of patients with hirsutism. ( Ayata, D; Bayram, F; Keleştimur, F; Müderris, II; Sahin, Y; Tutuş, A, 1996) |
| "The objective of this study was to compare the efficacy of flutamide and cyproterone acetate in the treatment of hirsutism." | 9.08 | Comparison of flutamide and cyproterone acetate in the treatment of hirsutism: a randomized controlled trial. ( Antoniou, G; Giannikos, L; Grigoriou, O; Karakitsos, P; Konidaris, S; Papadias, C, 1996) |
| "Flutamide is effective in the treatment of hirsutism but requires constant surveillance of liver function." | 9.08 | Flutamide in the treatment of hirsutism: long-term clinical effects, endocrine changes, and androgen receptor behavior. ( Armanini, D; Castello, R; Fontanarosa, MC; Magnani, CM; Moghetti, P; Muggeo, M; Negri, C; Tosi, F, 1995) |
| "Forty-four hirsute patients with polycystic ovary syndrome were randomly treated with finasteride (5 mg daily) or flutamide (250 mg twice daily) for 6 consecutive months." | 9.08 | Treatment of hirsutism by finasteride and flutamide in women with polycystic ovary syndrome. ( De Fusco, D; Eleftheriou, G; Falsetti, L; Rosina, B, 1997) |
| "The aim of this work was to evaluate the efficacy of two new antiandrogen drugs, finasteride and flutamide, in 80 hirsute patients: 44 with Polycystic Ovary Syndrome (PCOS) and 36 with Idiopathic Hirsutism (IH)." | 9.08 | [Finasteride and flutamide in the treatment of hirsutism]. ( De Fusco, D; Falsetti, L; Rosina, B, 1997) |
| "Twenty-two polycystic ovarian disease (PCOD) patients with hirsutism were treated with flutamide (250 mg twice/d) in association with ethinyl-E2 (0." | 9.07 | Treatment of hirsutism with flutamide and a low-dosage oral contraceptive in polycystic ovarian disease patients. ( Aglianò, A; Cianci, A; Ciotta, L; Marletta, E; Palumbo, G; Pisana, L, 1994) |
| "In this study the efficacy of flutamide, an antiandrogen which does not have a steroid structure, or progestational and estrogenic activities, on hirsutism and hormone levels in polycystic ovary syndrome (PCOS) and idiopathic hirsutism (IH) was investigated." | 9.07 | The use of antiandrogen flutamide in the treatment of hirsutism. ( Başkal, N; Cesur, V; Erdoğan, G; Kamel, N; Uysal, AR, 1994) |
| "To compare the clinical efficacy and safety of the pure antiandrogen flutamide and the steroidal derivative spironolactone in the treatment of hirsutism in women." | 9.07 | Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial. ( Cusan, L; Dupont, A; Gomez, JL; Labrie, F; Tremblay, RR, 1994) |
| "To compare the efficacy of two antiandrogens, spironolactone and flutamide, in the treatment of hirsutism." | 9.07 | Comparison of the efficacy of spironolactone versus flutamide in the treatment of hirsutism. ( Demirçay, Z; Durmuşoğlu, F; Erenus, M; Gürbüz, O; Pekin, S, 1994) |
| "Flutamide is an effective drug in treatment of hirsutism." | 7.75 | The risk of hepatotoxicity during long-term and low-dose flutamide treatment in hirsutism. ( Akcali, C; Balat, O; Cicek, H; Dikensoy, E; Pence, S, 2009) |
| "To investigate the clinical efficacy and safety of the finasteride (5 mg/day) plus flutamide (125 mg/day) combination therapy in unselected women with hirsutism, 44 women were involved in the study." | 7.75 | A comparison between finasteride, flutamide, and finasteride plus flutamide combination in the treatment of hirsutism. ( Karaca, Z; Kelestimur, F; Ozel, D; Tanriverdi, F; Unluhizarci, K, 2009) |
| "We describe the case of a 26-year-old girl with amenorrhea and severe hirsutism who was treated with flutamide 250 mg/day and developed liver toxicity during therapy." | 7.75 | Hepatotoxicity during low-dose flutamide treatment for hirsutism. ( Castelo-Branco, C; Del Pino, M, 2009) |
| "The authors hope that flutamide could enter in the list of medicines normally used to treat the beauty flaws of policistic acne and to restore a hormonal order associated to an effective contraception." | 7.74 | [Low-dose flutamide in the treatment of hyperandrogenism in adolescents]. ( Borrielli, I; Dinatale, A; Dugo, C; Dugo, N; Fattori, A; Mastroeni, MT; Pizzo, A, 2008) |
| "The aim of our study was to evaluate the clinical efficacy of flutamide (Flu), when used alone, on the course of hirsutism and to assess its effect on hormonal secretion." | 7.69 | The use of flutamide in the management of hirsutism. ( Badaracco, B; Bernasconi, D; Del Monte, P; Marugo, M; Meozzi, M; Primarolo, P; Zino, V, 1994) |
| "Flutamide, which interacts only with the androgen receptor, is effective for hirsutism, acne and seborrhoea, and does not disturb menstrual cyclicity or ovulation." | 7.68 | The impact of a pure anti-androgen (flutamide) on LH, FSH, androgens and clinical status in idiopathic hirsutism. ( Couzinet, B; Pholsena, M; Schaison, G; Young, J, 1993) |
| "The effectiveness of the antiandrogen flutamide in combination with an oral contraceptive was studied in 20 patients with moderate to severe hirsutism." | 7.68 | Treatment of hirsutism with the pure antiandrogen flutamide. ( Bélanger, A; Cusan, L; Dupont, A; Labrie, F; Manhes, G; Tremblay, RR, 1990) |
| "To explore the clinical usefulness of the antiandrogen flutamide in the treatment modality for hirsutism in women." | 7.68 | Treatment of hirsutism in women with flutamide. ( Kirschner, MA; Luthold, WW; Marcondes, JA; Minnani, SL; Samojlik, E; Wajchenberg, BL, 1992) |
| "Hirsutism was evaluated by the Ferriman-Gallwey score, and hair diameter and hair growth rate were determined by a special image analysis processor in basal conditions and after 90, 180, 270, and 360 days of treatment." | 6.69 | A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism. ( Bagnoli, A; Colombo, FM; Flamigni, C; Macrelli, S; Marescalchi, O; Paradisi, R; Ravaioli, B; Venturoli, S, 1999) |
| "Hyperandrogenism is a condition affecting 5-10% of adolescents." | 5.48 | Very low dose of flutamide in the treatment of hyperandrogenism. ( Canu, E; Fulghesu, AM; Melis, F; Melis, GB; Murru, G, 2018) |
| "Hirsutism was defined by modified Ferriman-Gallwey score (FGS)." | 5.32 | Serum prostate specific antigen levels in women with polycystic ovary syndrome and the effect of flutamide+desogestrel/ethinyl estradiol combination. ( Bahceci, M; Bahceci, S; Bilge, M; Tuzcu, A; Tuzcu, S, 2004) |
| "Hirsutism is a common symptom of women affected by polycystic ovary syndrome (PCOS)." | 5.29 | Prolonged treatment of hirsutism with flutamide alone in patients affected by polycystic ovary syndrome. ( Angelini, F; Barletta, D; Gargani, M; Genazzani, AD; Genazzani, AR; Lippi, F; Luisi, M; Monzani, F; Pucci, E, 1995) |
| "To evaluate the long-term safety and tolerability of flutamide therapy for hirsutism." | 5.14 | Long-term safety and tolerability of flutamide for the treatment of hirsutism. ( Balasch, J; Castelo-Branco, C; Gómez, O; Moyano, D, 2009) |
| " Twenty-nine women with hirsutism as a consequence of PCOS or idiopathic hirsutism were randomly assigned to receive 250 mg/day flutamide alone or 100 mg/day spironolactone plus a combination tablet of 2 mg CPA/35 microg EE, for 6 months." | 5.13 | Comparison of the clinical efficacy of flutamide and spironolactone plus ethinyloestradiol/cyproterone acetate in the treatment of hirsutism: a randomised controlled study. ( Aral, Y; Bavbek, N; Culha, C; Demirbas, B; Güler, S; Karakurt, F; Sahin, I; Serter, R, 2008) |
| " All flutamide doses induced a significant decrease in hirsutism, acne, and seborrhea scores after 12 months compared with placebo without differences among dose levels." | 5.12 | Long-term efficacy and tolerability of flutamide combined with oral contraception in moderate to severe hirsutism: a 12-month, double-blind, parallel clinical trial. ( Alcañiz, J; Calaf, J; Callejo, J; Escobar-Jiménez, F; Espinós, JJ; Fortuny, A; López, E; Millet, A; Torres, E; Vidal, O, 2007) |
| "To assess the effectiveness of flutamide in the treatment of hirsutism, used as monotherapy or combined with oral contraceptives (OC)." | 5.11 | [Effectiveness of flutamide alone or combined with oral contraceptives in the treatment of hirsutism in women]. ( Aravena, L; Devoto, E, 2004) |
| "To compare the effectiveness of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism (IH)." | 5.11 | Comparison of the clinical efficacy of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism: a randomized controlled study. ( Inal, MM; Taner, CE; Yildirim, Y, 2005) |
| "To compare the clinical, hormonal, biochemical and hemotological effects of flutamide versus flutamide plus an oral contraceptive (OC) in the treatment of hirsutism." | 5.10 | Comparison of the clinical efficacy and safety of flutamide versus flutamide plus an oral contraceptive in the treatment of hirsutism. ( Başogul, O; Inal, M; Ispahi, C; Karanfil, C; Onoglu, A; Taner, C; Tinar, S, 2002) |
| "To investigate insulin metabolism and its modifications induced by the administration of flutamide, a specific antiandrogen compound, in women with idiopathic hirsutism (IH) and in nonobese women with polycystic ovary syndrome (PCOS)." | 5.09 | Treatment with flutamide improves hyperinsulinemia in women with idiopathic hirsutism. ( Ajossa, S; Cagnacci, A; Guerriero, S; Melis, GB; Orrù, M; Paoletti, AM, 1999) |
| "Eighty-one hirsute women referred to a tertiary hirsutism clinic were assigned to one of three regimens: spironolactone 100 mg/day with an oral contraceptive, cyproterone acetate 50 mg/day on days 1 to 10 with an oral contraceptive, or flutamide 250 mg twice a day." | 5.09 | Recurrence rate of hirsutism after 3 different antiandrogen therapies. ( Durmuşoğlu, F; Erenus, M; Gürbüz, O; Yücelten, D, 1999) |
| "To compare the effectiveness of finasteride and flutamide in the treatment of hirsutism in patients with polycystic ovary syndrome (PCOS) and with idiopathic hirsutism." | 5.09 | Comparison of finasteride versus flutamide in the treatment of hirsutism. ( Bugari, G; Falsetti, L; Gambera, A; Iacobello, C; Legrenzi, L, 1999) |
| "To compare triptorelin, cyproterone acetate (CPA), and flutamide, in combination with an oral contraceptive, in the treatment of hirsutism." | 5.09 | Prospective randomized study comparing the long-acting gonadotropin-releasing hormone agonist triptorelin, flutamide, and cyproterone acetate, used in combination with an oral contraceptive, in the treatment of hirsutism. ( Balsa, J; Escobar-Morreale, HF; Pazos, F; Sancho, JM; Varela, C, 1999) |
| "To compare objectively the efficacies of spironolactone (100 mg/day), flutamide (250 mg/day), and finasteride (5 mg/day) in the treatment of hirsutism, 40 hirsute women were randomly assigned to double blind treatments with 1 of these 3 drugs or placebo for 6 months." | 5.09 | Comparison of spironolactone, flutamide, and finasteride efficacy in the treatment of hirsutism: a randomized, double blind, placebo-controlled trial. ( Caputo, M; Castello, R; Misciali, C; Moghetti, P; Muggeo, M; Negri, C; Perrone, F; Tosi, F; Tosti, A, 2000) |
| "To compare the long-term (1 year) effects of flutamide (250 mg/d) and finasteride (5 mg/d) for the treatment of hirsutism in women." | 5.09 | A prospective, randomized trial comparing flutamide (250 mg/d) and finasteride (5 mg/d) in the treatment of hirsutism. ( Bayram, F; Güven, M; Müderris, II, 2000) |
| " Flutamide, a nonsteroidal antiandrogen, is known to be effective in reducing hirsutism in patients with ovarian hyperandrogenism." | 5.09 | Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in nonobese, adolescent girls: effect of flutamide. ( de Zegher, F; Ibáñez, L; Marcos, MV; Potau, N, 2000) |
| "The objective of this prospective randomized study was to evaluate and compare the hormonal and clinical effects of long-acting gonadotropin-releasing hormone (GnRH) agonist and a combination of GnRH agonist with combined oral contraceptive (COC) or flutamide in women with polycystic ovary syndrome (PCOS)." | 5.09 | Hormonal and clinical effects of GnRH agonist alone, or in combination with a combined oral contraceptive or flutamide in women with severe hirsutism. ( Caruso, A; De Leo, V; Fulghesu, AM; la Marca, A; Morgante, G; Pasqui, L; Talluri, B; Torricelli, M, 2000) |
| "Finasteride, CPA, and flutamide are equally effective in decreasing hirsutism, despite different mechanisms of action." | 5.09 | Treatment of hirsutism: comparisons between different antiandrogens with central and peripheral effects. ( Bersi, C; Fruzzetti, F; Genazzani, AR; Parrini, D; Ricci, C, 1999) |
| "To compare the effectiveness of finasteride and flutamide in the treatment of idiopathic hirsutism." | 5.09 | Comparison of finasteride and flutamide in the treatment of idiopathic hirsutism. ( Falsetti, L; Gambera, A, 1999) |
| "The aim of this work was to evaluate the efficacy of two new antiandrogen drugs, finasteride and flutamide, in 80 hirsute patients: 44 with Polycystic Ovary Syndrome (PCOS) and 36 with Idiopathic Hirsutism (IH)." | 5.08 | [Finasteride and flutamide in the treatment of hirsutism]. ( De Fusco, D; Falsetti, L; Rosina, B, 1997) |
| "Flutamide is effective in the treatment of hirsutism but requires constant surveillance of liver function." | 5.08 | Flutamide in the treatment of hirsutism: long-term clinical effects, endocrine changes, and androgen receptor behavior. ( Armanini, D; Castello, R; Fontanarosa, MC; Magnani, CM; Moghetti, P; Muggeo, M; Negri, C; Tosi, F, 1995) |
| "Forty-four hirsute patients with polycystic ovary syndrome were randomly treated with finasteride (5 mg daily) or flutamide (250 mg twice daily) for 6 consecutive months." | 5.08 | Treatment of hirsutism by finasteride and flutamide in women with polycystic ovary syndrome. ( De Fusco, D; Eleftheriou, G; Falsetti, L; Rosina, B, 1997) |
| "High doses of flutamide, which is the only antiandrogen that specifically blocks the androgen receptor, have recently been used with good clinical results in women with hirsutism." | 5.08 | Clinical efficacy and safety of low-dose flutamide alone and combined with an oral contraceptive for the treatment of idiopathic hirsutism. ( Cédrin, I; Dodin, S; Faure, N; Guy, J; Lemay, A; Méchain, C; Turcot-Lemay, L, 1995) |
| "To investigate the effects of low dose flutamide (250 mg/d) on hirsutism score and hormone levels in women with hirsutism." | 5.08 | The efficacy of 250 mg/day flutamide in the treatment of patients with hirsutism. ( Ayata, D; Bayram, F; Keleştimur, F; Müderris, II; Sahin, Y; Tutuş, A, 1996) |
| "To compare the clinical efficacy and safety of the pure antiandrogen flutamide and the steroidal derivative spironolactone in the treatment of hirsutism in women." | 5.07 | Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial. ( Cusan, L; Dupont, A; Gomez, JL; Labrie, F; Tremblay, RR, 1994) |
| "To compare the efficacy of two antiandrogens, spironolactone and flutamide, in the treatment of hirsutism." | 5.07 | Comparison of the efficacy of spironolactone versus flutamide in the treatment of hirsutism. ( Demirçay, Z; Durmuşoğlu, F; Erenus, M; Gürbüz, O; Pekin, S, 1994) |
| "Twenty-two polycystic ovarian disease (PCOD) patients with hirsutism were treated with flutamide (250 mg twice/d) in association with ethinyl-E2 (0." | 5.07 | Treatment of hirsutism with flutamide and a low-dosage oral contraceptive in polycystic ovarian disease patients. ( Aglianò, A; Cianci, A; Ciotta, L; Marletta, E; Palumbo, G; Pisana, L, 1994) |
| "Hirsutism was assessed before and after 3 months of treatment with flutamide 500 mg/d." | 5.07 | Clinical and endocrine effects of flutamide in hyperandrogenic women. ( De Lorenzo, D; Fioretti, P; Fruzzetti, F; Ricci, C, 1993) |
| "In this systematic review we present information relating to the effectiveness and safety of the following interventions: finasteride, flutamide, metformin, spironolactone, cyproterone acetate-ethinylestradiol (co-cyprindiol), interventions to achieve weight loss, ketoconazole, and mechanical hair removal." | 4.85 | PCOS. ( Cahill, D, 2009) |
| " A significant reduction in hirsutism was found for flutamide, spironolactone, cyproterone acetate combined with an oral contraceptive, thiazolidinediones, oral contraceptive pills (OCPs), finasteride and metformin but not for placebo." | 4.84 | A systematic review of commonly used medical treatments for hirsutism in women. ( Conway, GS; Koulouri, O, 2008) |
| "Patients under flutamide therapy showed significant improvements in hirsutism scores after 6 months of treatment with a maximum effect at 12 months that was maintained during all the therapy time." | 3.83 | Long-term satisfaction and tolerability with low-dose flutamide: a 20-year surveillance study on 120 hyperandrogenic women. ( Alvarez-Olivares, L; Balasch, J; Castelo-Branco, C; Hernández-Angeles, C, 2016) |
| "Flutamide is an effective drug in treatment of hirsutism." | 3.75 | The risk of hepatotoxicity during long-term and low-dose flutamide treatment in hirsutism. ( Akcali, C; Balat, O; Cicek, H; Dikensoy, E; Pence, S, 2009) |
| "We describe the case of a 26-year-old girl with amenorrhea and severe hirsutism who was treated with flutamide 250 mg/day and developed liver toxicity during therapy." | 3.75 | Hepatotoxicity during low-dose flutamide treatment for hirsutism. ( Castelo-Branco, C; Del Pino, M, 2009) |
| "The authors hope that flutamide could enter in the list of medicines normally used to treat the beauty flaws of policistic acne and to restore a hormonal order associated to an effective contraception." | 3.74 | [Low-dose flutamide in the treatment of hyperandrogenism in adolescents]. ( Borrielli, I; Dinatale, A; Dugo, C; Dugo, N; Fattori, A; Mastroeni, MT; Pizzo, A, 2008) |
| " In 8 male patients, mean age 75 years (range 65-83), flutamide was indicated for palliative therapy of disseminated prostatic carcinoma, and in one young female (14 years) was given for the treatment of facial hirsutism." | 3.71 | Flutamide-induced hepatotoxicity: report of a case series. ( Alcántara, R; Andrade, RJ; Camargo, R; Fernández, MC; Ferrer, T; Fraga, E; García Cortés, M; García-Ruiz, E; Lucena, MI; Martín-Vivaldi, R; Montero, JL; Peláez, G; Pizarro, MA; Romero-Gómez, M; Rosemary-Gómez, M; Sánchez Martínez, H; Suárez, F, 2001) |
| "The aim of our study was to evaluate the clinical efficacy of flutamide (Flu), when used alone, on the course of hirsutism and to assess its effect on hormonal secretion." | 3.69 | The use of flutamide in the management of hirsutism. ( Badaracco, B; Bernasconi, D; Del Monte, P; Marugo, M; Meozzi, M; Primarolo, P; Zino, V, 1994) |
| "Flutamide, which interacts only with the androgen receptor, is effective for hirsutism, acne and seborrhoea, and does not disturb menstrual cyclicity or ovulation." | 3.68 | The impact of a pure anti-androgen (flutamide) on LH, FSH, androgens and clinical status in idiopathic hirsutism. ( Couzinet, B; Pholsena, M; Schaison, G; Young, J, 1993) |
| "To explore the clinical usefulness of the antiandrogen flutamide in the treatment modality for hirsutism in women." | 3.68 | Treatment of hirsutism in women with flutamide. ( Kirschner, MA; Luthold, WW; Marcondes, JA; Minnani, SL; Samojlik, E; Wajchenberg, BL, 1992) |
| "We studied the effect of flutamide, a peripheral androgenic blocking agent, 500 mg daily for 28 days in 7 non ovulating patients with hirsutism." | 3.68 | [The effect of a peripheral androgenic blockade on plasma lipoproteins in hirsutism patients]. ( Acosta, AM; Arteaga, A; Arteaga, E; Correa, R; Fernández, C; López, X, 1990) |
| "Hirsutism was evaluated by the Ferriman-Gallwey score, and hair diameter and hair growth rate were determined by a special image analysis processor in basal conditions and after 90, 180, 270, and 360 days of treatment." | 2.69 | A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism. ( Bagnoli, A; Colombo, FM; Flamigni, C; Macrelli, S; Marescalchi, O; Paradisi, R; Ravaioli, B; Venturoli, S, 1999) |
| "Flutamide treatment determined a clinical, marked improvement of androgen hypersensitivity (Ferriman-Gallwey score: before 22." | 2.68 | Androgen-receptor blockade does not impair bone mineral density in adolescent females. ( Baroncelli, GI; Battini, R; Bertelloni, S; Costa, S; Saggese, G; Sorrentino, MC, 1997) |
| "Flutamide was more effective than placebo in two studies (MD -7·60, 95% CI: -10·53 to -4·67 and MD -7·20, 95% CI: -10·15 to -4·25), as was spironolactone (MD -7·69, 95% CI: -10·12 to -5·26)." | 2.53 | Interventions for hirsutism excluding laser and photoepilation therapy alone: abridged Cochrane systematic review including GRADE assessments. ( Fedorowicz, Z; van Zuuren, EJ, 2016) |
| "Although hirsutism and androgenetic alopecia are cosmetic problems, they can be psychologically devastating for women." | 2.40 | Antiandrogen treatment of polycystic ovary syndrome. ( Rittmaster, RS, 1999) |
| "Hyperandrogenism is a condition affecting 5-10% of adolescents." | 1.48 | Very low dose of flutamide in the treatment of hyperandrogenism. ( Canu, E; Fulghesu, AM; Melis, F; Melis, GB; Murru, G, 2018) |
| "Polycystic ovary syndrome is the underlying cause in the vast majority of patients with hirsutism; however, it should be kept in mind that it can only be diagnosed after exclusion of some other diseases such as non-classical congenital adrenal hyperplasia, Cushing's syndrome, hyperprolactinemia and acromegaly." | 1.39 | Hirsutism - from diagnosis to use of antiandrogens. ( Karaca, Z; Kelestimur, F; Unluhizarci, K, 2013) |
| "Hirsutism was defined by modified Ferriman-Gallwey score (FGS)." | 1.32 | Serum prostate specific antigen levels in women with polycystic ovary syndrome and the effect of flutamide+desogestrel/ethinyl estradiol combination. ( Bahceci, M; Bahceci, S; Bilge, M; Tuzcu, A; Tuzcu, S, 2004) |
| "Hirsutism is the manifestation of hyperandrogenemia in PCOS." | 1.32 | The treatment of polycystic ovary syndrome. ( Ajossa, S; Guerriero, S; Melis, GB; Orrù, M; Paoletti, AM, 2004) |
| "Hirsutism is a common symptom of women affected by polycystic ovary syndrome (PCOS)." | 1.29 | Prolonged treatment of hirsutism with flutamide alone in patients affected by polycystic ovary syndrome. ( Angelini, F; Barletta, D; Gargani, M; Genazzani, AD; Genazzani, AR; Lippi, F; Luisi, M; Monzani, F; Pucci, E, 1995) |
| "Flutamide is a potent hepatotoxin in certain patients." | 1.29 | Flutamide hepatotoxicity. ( Fourcroy, JL; Wysowski, DK, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.14) | 18.7374 |
| 1990's | 44 (50.00) | 18.2507 |
| 2000's | 29 (32.95) | 29.6817 |
| 2010's | 13 (14.77) | 24.3611 |
| 2020's | 1 (1.14) | 2.80 |
| Authors | Studies |
|---|---|
| Zolton, JR | 1 |
| Fulghesu, AM | 2 |
| Melis, F | 1 |
| Murru, G | 1 |
| Canu, E | 1 |
| Melis, GB | 3 |
| Azarchi, S | 1 |
| Bienenfeld, A | 1 |
| Lo Sicco, K | 1 |
| Marchbein, S | 1 |
| Shapiro, J | 1 |
| Nagler, AR | 1 |
| Boztosun, A | 1 |
| Açmaz, G | 1 |
| Ozturk, A | 1 |
| Müderris, II | 6 |
| Unluhizarci, K | 2 |
| Karaca, Z | 2 |
| Kelestimur, F | 5 |
| Ibáñez, L | 6 |
| Ong, KK | 1 |
| López-Bermejo, A | 1 |
| Dunger, DB | 2 |
| de Zegher, F | 6 |
| Buzney, E | 1 |
| Sheu, J | 1 |
| Buzney, C | 1 |
| Reynolds, RV | 1 |
| van Zuuren, EJ | 2 |
| Fedorowicz, Z | 2 |
| Carter, B | 1 |
| Pandis, N | 1 |
| Díaz, M | 1 |
| Gallego-Escuredo, JM | 1 |
| Villarroya, F | 1 |
| Castelo-Branco, C | 3 |
| Hernández-Angeles, C | 1 |
| Alvarez-Olivares, L | 1 |
| Balasch, J | 2 |
| Dikensoy, E | 1 |
| Balat, O | 1 |
| Pence, S | 1 |
| Akcali, C | 1 |
| Cicek, H | 1 |
| Pizzo, A | 1 |
| Borrielli, I | 1 |
| Mastroeni, MT | 1 |
| Fattori, A | 1 |
| Dugo, C | 1 |
| Dugo, N | 1 |
| Dinatale, A | 1 |
| Ozel, D | 1 |
| Tanriverdi, F | 1 |
| Cahill, D | 1 |
| Del Pino, M | 1 |
| Bachelot, A | 1 |
| Chabbert-Buffet, N | 1 |
| Salenave, S | 1 |
| Kerlan, V | 1 |
| Galand-Portier, MB | 1 |
| Paradisi, R | 3 |
| Venturoli, S | 3 |
| Taner, C | 1 |
| Inal, M | 1 |
| Başogul, O | 1 |
| Onoglu, A | 1 |
| Karanfil, C | 1 |
| Tinar, S | 1 |
| Ispahi, C | 1 |
| Ajossa, S | 2 |
| Guerriero, S | 2 |
| Paoletti, AM | 2 |
| Orrù, M | 2 |
| Sahin, Y | 3 |
| Bahceci, M | 1 |
| Bilge, M | 1 |
| Tuzcu, A | 1 |
| Tuzcu, S | 1 |
| Bahceci, S | 1 |
| Devoto, E | 1 |
| Aravena, L | 1 |
| Al-Inany, H | 1 |
| Inal, MM | 1 |
| Yildirim, Y | 1 |
| Taner, CE | 1 |
| Calaf, J | 1 |
| López, E | 1 |
| Millet, A | 1 |
| Alcañiz, J | 1 |
| Fortuny, A | 1 |
| Vidal, O | 1 |
| Callejo, J | 1 |
| Escobar-Jiménez, F | 1 |
| Torres, E | 1 |
| Espinós, JJ | 1 |
| Koulouri, O | 1 |
| Conway, GS | 1 |
| Moyano, D | 1 |
| Gómez, O | 1 |
| Karakurt, F | 1 |
| Sahin, I | 1 |
| Güler, S | 1 |
| Demirbas, B | 1 |
| Culha, C | 1 |
| Serter, R | 1 |
| Aral, Y | 1 |
| Bavbek, N | 1 |
| Wysowski, DK | 2 |
| Fourcroy, JL | 2 |
| Moghetti, P | 4 |
| Castello, R | 4 |
| Negri, C | 4 |
| Tosi, F | 4 |
| Magnani, CM | 1 |
| Fontanarosa, MC | 1 |
| Armanini, D | 1 |
| Muggeo, M | 4 |
| Presl, J | 1 |
| Howe, RS | 1 |
| Chow, RP | 1 |
| Stevens, CL | 1 |
| Erenus, M | 3 |
| Motta, T | 2 |
| Maggi, G | 2 |
| D'Alberton, A | 2 |
| Cesur, V | 1 |
| Kamel, N | 1 |
| Uysal, AR | 1 |
| Erdoğan, G | 1 |
| Başkal, N | 1 |
| Ciotta, L | 1 |
| Cianci, A | 1 |
| Marletta, E | 1 |
| Pisana, L | 1 |
| Aglianò, A | 1 |
| Palumbo, G | 1 |
| Marugo, M | 1 |
| Bernasconi, D | 1 |
| Meozzi, M | 1 |
| Del Monte, P | 1 |
| Zino, V | 1 |
| Primarolo, P | 1 |
| Badaracco, B | 1 |
| Wallace, C | 1 |
| Lalor, EA | 1 |
| Chik, CL | 1 |
| Gürbüz, O | 2 |
| Durmuşoğlu, F | 2 |
| Demirçay, Z | 1 |
| Pekin, S | 1 |
| Koning, RP | 1 |
| Fruzzetti, F | 2 |
| De Lorenzo, D | 1 |
| Ricci, C | 2 |
| Fioretti, P | 1 |
| Cusan, L | 2 |
| Dupont, A | 2 |
| Gomez, JL | 1 |
| Tremblay, RR | 2 |
| Labrie, F | 2 |
| Couzinet, B | 1 |
| Pholsena, M | 1 |
| Young, J | 1 |
| Schaison, G | 1 |
| Grimaldi, F | 1 |
| Proto, G | 1 |
| Bertolissi, F | 1 |
| Pucci, E | 1 |
| Genazzani, AD | 1 |
| Monzani, F | 1 |
| Lippi, F | 1 |
| Angelini, F | 1 |
| Gargani, M | 1 |
| Barletta, D | 1 |
| Luisi, M | 1 |
| Genazzani, AR | 2 |
| Dodin, S | 1 |
| Faure, N | 1 |
| Cédrin, I | 1 |
| Méchain, C | 1 |
| Turcot-Lemay, L | 1 |
| Guy, J | 1 |
| Lemay, A | 1 |
| Bayram, F | 5 |
| Tutuş, A | 1 |
| Ayata, D | 1 |
| Grigoriou, O | 1 |
| Papadias, C | 1 |
| Konidaris, S | 1 |
| Antoniou, G | 1 |
| Karakitsos, P | 1 |
| Giannikos, L | 1 |
| Zemtsov, A | 1 |
| Wilson, L | 1 |
| Bertelloni, S | 1 |
| Baroncelli, GI | 1 |
| Sorrentino, MC | 1 |
| Costa, S | 1 |
| Battini, R | 1 |
| Saggese, G | 1 |
| Falsetti, L | 4 |
| De Fusco, D | 2 |
| Eleftheriou, G | 1 |
| Rosina, B | 2 |
| Young, R | 1 |
| Sinclair, R | 1 |
| Pazos, F | 1 |
| Escobar-Morreale, HF | 1 |
| Balsa, J | 1 |
| Sancho, JM | 1 |
| Varela, C | 1 |
| Bersi, C | 1 |
| Parrini, D | 1 |
| Zamberlan, N | 1 |
| Rossini, M | 1 |
| Gatti, D | 1 |
| Adami, S | 1 |
| Marescalchi, O | 1 |
| Colombo, FM | 2 |
| Macrelli, S | 1 |
| Ravaioli, B | 2 |
| Bagnoli, A | 2 |
| Flamigni, C | 1 |
| Rittmaster, RS | 1 |
| Yücelten, D | 1 |
| Gambera, A | 2 |
| Andrade, RJ | 2 |
| Lucena, MI | 2 |
| Fernández, MC | 2 |
| Suárez, F | 2 |
| Montero, JL | 2 |
| Fraga, E | 2 |
| Hidalgo, F | 1 |
| Cagnacci, A | 1 |
| Legrenzi, L | 1 |
| Iacobello, C | 1 |
| Bugari, G | 1 |
| Dorizzi, R | 1 |
| Fortunato, A | 1 |
| Spiazzi, GG | 1 |
| Tosti, A | 1 |
| Misciali, C | 1 |
| Perrone, F | 1 |
| Caputo, M | 1 |
| Güven, M | 2 |
| Román Llorente, FJ | 1 |
| Alvarez Navascués, C | 1 |
| Suárez González, A | 1 |
| González Bernal, AC | 1 |
| Potau, N | 1 |
| Marcos, MV | 1 |
| De Leo, V | 1 |
| la Marca, A | 1 |
| Morgante, G | 1 |
| Pasqui, L | 1 |
| Talluri, B | 1 |
| Torricelli, M | 1 |
| Caruso, A | 1 |
| Ruiz-Rebollo, M | 1 |
| Atienza-Sánchez, R | 1 |
| López-García, E | 1 |
| García Cortés, M | 1 |
| Sánchez Martínez, H | 1 |
| Ferrer, T | 1 |
| Martín-Vivaldi, R | 1 |
| Peláez, G | 1 |
| Romero-Gómez, M | 1 |
| Camargo, R | 1 |
| Alcántara, R | 1 |
| Pizarro, MA | 1 |
| García-Ruiz, E | 1 |
| Rosemary-Gómez, M | 1 |
| Lószió, FA | 1 |
| Tóth, S | 1 |
| Kocsis, J | 1 |
| Szécsi, M | 1 |
| Vianello, F | 1 |
| Mancini, F | 1 |
| Gualerzi, B | 1 |
| Porcu, E | 1 |
| Seracchioli, R | 1 |
| Neri, RO | 1 |
| Marcondes, JA | 1 |
| Minnani, SL | 1 |
| Luthold, WW | 1 |
| Wajchenberg, BL | 1 |
| Samojlik, E | 1 |
| Kirschner, MA | 1 |
| Perra, M | 1 |
| Azzolari, E | 1 |
| Casazza, S | 1 |
| Sciarra, F | 1 |
| Toscano, V | 1 |
| Concolino, G | 1 |
| Di Silverio, F | 1 |
| Correa, R | 1 |
| Arteaga, E | 1 |
| López, X | 1 |
| Arteaga, A | 1 |
| Fernández, C | 1 |
| Acosta, AM | 1 |
| Bélanger, A | 1 |
| Manhes, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gender Affirmative Treatment of Hypertrichosis With Intense Pulsed Light - Effect on Hair Reduction and Quality of Life[NCT05775328] | 39 participants (Anticipated) | Observational | 2023-12-01 | Not yet recruiting | |||
| Clinical Metabolic and Endocrine Parameters in Response to Metformin and Lifestyle Intervention in Women With Polycystic Ovary Syndrome: A Phase 4 Randomized, Double- Blind and Placebo Control Trial[NCT00679679] | Phase 4 | 30 participants (Actual) | Interventional | 2003-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for flutamide and Hirsutism
| Article | Year |
|---|---|
Androgens in women: Hormone-modulating therapies for skin disease.
Topics: 5-alpha Reductase Inhibitors; Acne Vulgaris; Adrenal Hyperplasia, Congenital; Alopecia; Androgen Ant | 2019 |
Polycystic ovary syndrome: a review for dermatologists: Part II. Treatment.
Topics: 5-alpha Reductase Inhibitors; Acne Vulgaris; Alopecia; Androgen Antagonists; Contraceptives, Oral, C | 2014 |
Interventions for hirsutism (excluding laser and photoepilation therapy alone).
Topics: 5-alpha Reductase Inhibitors; Adult; Androgen Antagonists; Body Mass Index; Contraceptive Agents, Fe | 2015 |
Interventions for hirsutism excluding laser and photoepilation therapy alone: abridged Cochrane systematic review including GRADE assessments.
Topics: 5-alpha Reductase Inhibitors; Adolescent; Androgen Antagonists; Body Mass Index; Contraceptives, Ora | 2016 |
PCOS.
Topics: Diabetes Mellitus, Type 2; Flutamide; Hair Removal; Hirsutism; Humans; Metformin; Polycystic Ovary S | 2009 |
Anti-androgen treatments.
Topics: Androgen Antagonists; Cyproterone Acetate; Estrogens; Female; Finasteride; Flutamide; Gonadotropin-R | 2010 |
Medical treatment regimens of hirsutism.
Topics: Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Enzyme Inhibitors; Ethinyl Estradiol; | 2004 |
Polycystic ovary syndrome.
Topics: Androgen Antagonists; Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Fin | 2004 |
A systematic review of commonly used medical treatments for hirsutism in women.
Topics: Androgen Antagonists; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Drug Therapy, Combination | 2008 |
Hirsutes. II: Treatment.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgen Receptor Antagonists; Contraceptives, O | 1998 |
Antiandrogen treatment of polycystic ovary syndrome.
Topics: Alopecia; Androgen Antagonists; Androgens; Cyproterone Acetate; Female; Finasteride; Flutamide; Hirs | 1999 |
Antiandrogens.
Topics: Acne Vulgaris; Androgen Antagonists; Animals; Biological Assay; Comb and Wattles; Cyproterone; Femal | 1976 |
38 trials available for flutamide and Hirsutism
| Article | Year |
|---|---|
Effects of ethinylestradiol-cyproterone acetate vs. pioglitazone-flutamide-metformin on plasma FGF21 levels in adolescent girls with androgen excess.
Topics: Adolescent; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Fibroblast Growth Fac | 2016 |
Comparison of the clinical efficacy and safety of flutamide versus flutamide plus an oral contraceptive in the treatment of hirsutism.
Topics: Administration, Oral; Adult; Androgen Antagonists; Contraceptives, Oral; Cyproterone Acetate; Dehydr | 2002 |
[Effectiveness of flutamide alone or combined with oral contraceptives in the treatment of hirsutism in women].
Topics: Adolescent; Adult; Androgen Antagonists; Androgens; Biomarkers; Cohort Studies; Contraceptives, Oral | 2004 |
Comparison of the clinical efficacy of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism: a randomized controlled study.
Topics: Adult; Androgen Antagonists; Cyproterone Acetate; Diuretics; Drug Combinations; Drug Therapy, Combin | 2005 |
Long-term efficacy and tolerability of flutamide combined with oral contraception in moderate to severe hirsutism: a 12-month, double-blind, parallel clinical trial.
Topics: Acne Vulgaris; Adolescent; Adult; Androgen Antagonists; Contraceptives, Oral, Hormonal; Dermatitis, | 2007 |
Long-term safety and tolerability of flutamide for the treatment of hirsutism.
Topics: Adult; Androgen Antagonists; Contraceptives, Oral, Hormonal; Desogestrel; Ethinyl Estradiol; Female; | 2009 |
Comparison of the clinical efficacy of flutamide and spironolactone plus ethinyloestradiol/cyproterone acetate in the treatment of hirsutism: a randomised controlled study.
Topics: Adult; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Ethi | 2008 |
Flutamide in the treatment of hirsutism: long-term clinical effects, endocrine changes, and androgen receptor behavior.
Topics: Acne Vulgaris; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Femal | 1995 |
Efficacy of flutamide versus spironolactone.
Topics: Contraceptives, Oral; Female; Flutamide; Hirsutism; Humans; Incidence; Menstruation Disturbances; Sp | 1995 |
The use of antiandrogen flutamide in the treatment of hirsutism.
Topics: Adult; Female; Flutamide; Hirsutism; Humans; Luteinizing Hormone; Progesterone | 1994 |
Treatment of hirsutism with flutamide and a low-dosage oral contraceptive in polycystic ovarian disease patients.
Topics: Adolescent; Adult; Contraceptives, Oral; Desogestrel; Dose-Response Relationship, Drug; Drug Therapy | 1994 |
Comparison of the efficacy of spironolactone versus flutamide in the treatment of hirsutism.
Topics: Adolescent; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Follic | 1994 |
Clinical and endocrine effects of flutamide in hyperandrogenic women.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androgens; Estradiol; Female; Flutamide; Follicle S | 1993 |
Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicl | 1994 |
Clinical efficacy and safety of low-dose flutamide alone and combined with an oral contraceptive for the treatment of idiopathic hirsutism.
Topics: Adult; Androgen Antagonists; Contraceptives, Oral, Hormonal; Drug Administration Schedule; Drug Ther | 1995 |
The efficacy of 250 mg/day flutamide in the treatment of patients with hirsutism.
Topics: Adolescent; Adult; Androgen Antagonists; Androstenedione; Dose-Response Relationship, Drug; Estrogen | 1996 |
Comparison of flutamide and cyproterone acetate in the treatment of hirsutism: a randomized controlled trial.
Topics: Adolescent; Adult; Androgen Antagonists; Cyproterone; Female; Flutamide; Hirsutism; Hormones; Humans | 1996 |
Androgen-receptor blockade does not impair bone mineral density in adolescent females.
Topics: Absorptiometry, Photon; Acne Vulgaris; Adolescent; Adult; Analysis of Variance; Androgen Antagonists | 1997 |
Treatment of hirsutism by finasteride and flutamide in women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androgen Antagonists; Androstenedione; Dehydroepiandrosterone S | 1997 |
A comparison between two doses of flutamide (250 mg/d and 500 mg/d) in the treatment of hirsutism.
Topics: Adult; Androgen Antagonists; Dose-Response Relationship, Drug; Female; Flutamide; Hirsutism; Humans; | 1997 |
[Finasteride and flutamide in the treatment of hirsutism].
Topics: Administration, Oral; Adult; Androgen Antagonists; Dose-Response Relationship, Drug; Female; Finaste | 1997 |
Prospective randomized study comparing the long-acting gonadotropin-releasing hormone agonist triptorelin, flutamide, and cyproterone acetate, used in combination with an oral contraceptive, in the treatment of hirsutism.
Topics: Adult; Androgen Antagonists; Body Mass Index; Contraceptives, Oral, Hormonal; Cyproterone Acetate; D | 1999 |
Treatment of hirsutism: comparisons between different antiandrogens with central and peripheral effects.
Topics: Adolescent; Adult; Androgen Antagonists; Cyproterone Acetate; Female; Finasteride; Flutamide; Hirsut | 1999 |
Spironolactone, but not flutamide, administration prevents bone loss in hyperandrogenic women treated with gonadotropin-releasing hormone agonist.
Topics: Adult; Bone and Bones; Bone Density; Bone Resorption; Female; Flutamide; Hirsutism; Humans; Polycyst | 1999 |
A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism.
Topics: Adult; Cyproterone Acetate; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Hormones; | 1999 |
Clinical efficacy of lower dose flutamide 125 mg/day in the treatment of hirsutism.
Topics: Adolescent; Adult; Androgen Antagonists; Androstenedione; Dehydroepiandrosterone Sulfate; Estradiol; | 1999 |
Recurrence rate of hirsutism after 3 different antiandrogen therapies.
Topics: Androgen Antagonists; Contraceptives, Oral; Cyproterone; Female; Flutamide; Hirsutism; Humans; Lutei | 1999 |
Comparison of finasteride and flutamide in the treatment of idiopathic hirsutism.
Topics: Adolescent; Adult; Androgen Antagonists; Androstane-3,17-diol; Body Mass Index; Enzyme Inhibitors; F | 1999 |
Treatment with flutamide improves hyperinsulinemia in women with idiopathic hirsutism.
Topics: Adult; Androgen Antagonists; Blood Glucose; C-Peptide; Female; Flutamide; Follicle Stimulating Hormo | 1999 |
Comparison of finasteride versus flutamide in the treatment of hirsutism.
Topics: Adolescent; Adult; Androgen Antagonists; Enzyme Inhibitors; Female; Finasteride; Flutamide; Hirsutis | 1999 |
Antiandrogen drugs lower serum prostate-specific antigen (PSA) levels in hirsute subjects: evidence that serum PSA is a marker of androgen action in women.
Topics: Adult; Androgen Antagonists; Androgens; Androstane-3,17-diol; Biomarkers; Double-Blind Method; Enzym | 2000 |
Comparison of spironolactone, flutamide, and finasteride efficacy in the treatment of hirsutism: a randomized, double blind, placebo-controlled trial.
Topics: Adult; Androgen Antagonists; Double-Blind Method; Female; Finasteride; Flutamide; Hair; Hirsutism; H | 2000 |
A prospective, randomized trial comparing flutamide (250 mg/d) and finasteride (5 mg/d) in the treatment of hirsutism.
Topics: Adult; Androgen Antagonists; Body Mass Index; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Est | 2000 |
Treatment of hirsutism with lowest-dose flutamide (62.5 mg/day).
Topics: Adolescent; Adult; Androgen Antagonists; Female; Flutamide; Hirsutism; Hormones; Humans; Prospective | 2000 |
Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in nonobese, adolescent girls: effect of flutamide.
Topics: Adolescent; Androgen Antagonists; Blood Glucose; Female; Flutamide; Glucose Tolerance Test; Hirsutis | 2000 |
Hormonal and clinical effects of GnRH agonist alone, or in combination with a combined oral contraceptive or flutamide in women with severe hirsutism.
Topics: Adult; Amenorrhea; Androgen Antagonists; Contraceptives, Oral, Combined; Cyproterone Acetate; Estrad | 2000 |
Low-dose flutamide (125 mg/day) as maintenance therapy in the treatment of hirsutism.
Topics: Adult; Alanine Transaminase; Androgen Antagonists; Aspartate Aminotransferases; Dose-Response Relati | 2001 |
Antiandrogens: clinical applications.
Topics: Acne Vulgaris; Adult; Androgen Antagonists; Cyproterone; Cyproterone Acetate; Dermatitis, Seborrheic | 1990 |
38 other studies available for flutamide and Hirsutism
| Article | Year |
|---|---|
Polycystic ovarian syndrome: a second-take on flutamide.
Topics: Androgen Antagonists; Female; Flutamide; Hirsutism; Humans; Polycystic Ovary Syndrome | 2023 |
Very low dose of flutamide in the treatment of hyperandrogenism.
Topics: Acne Vulgaris; Adolescent; Androgen Antagonists; Androstenes; Dose-Response Relationship, Drug; Drug | 2018 |
Clinical efficacy of low dose flutamide plus Diane-35 in the treatment of idiopathic hirsutism and polycystic ovary syndrome.
Topics: Adult; Androgen Antagonists; Cyproterone Acetate; Drug Administration Schedule; Drug Combinations; D | 2013 |
Hirsutism - from diagnosis to use of antiandrogens.
Topics: Androgen Antagonists; Androstenes; Cyproterone Acetate; Female; Finasteride; Flutamide; Hirsutism; H | 2013 |
Hyperinsulinaemic androgen excess in adolescent girls.
Topics: Adolescent; Androgens; Drug Therapy, Combination; Dyslipidemias; Female; Flutamide; Hirsutism; Human | 2014 |
Long-term satisfaction and tolerability with low-dose flutamide: a 20-year surveillance study on 120 hyperandrogenic women.
Topics: Adult; Androgen Antagonists; Contraceptives, Oral, Hormonal; Drug Therapy, Combination; Female; Flut | 2016 |
The risk of hepatotoxicity during long-term and low-dose flutamide treatment in hirsutism.
Topics: Adolescent; Adult; Alanine Transaminase; Androgen Antagonists; Aspartate Aminotransferases; Chemical | 2009 |
[Low-dose flutamide in the treatment of hyperandrogenism in adolescents].
Topics: Acne Vulgaris; Adolescent; Androgen Antagonists; Body Mass Index; Child; Female; Flutamide; Follow-U | 2008 |
A comparison between finasteride, flutamide, and finasteride plus flutamide combination in the treatment of hirsutism.
Topics: Adult; Androgen Antagonists; Drug Therapy, Combination; Female; Finasteride; Flutamide; Hirsutism; H | 2009 |
Low-dose flutamide for women with androgen excess: anti-androgenic efficacy and hepatic safety.
Topics: Androgen Antagonists; Androgens; Chemical and Drug Induced Liver Injury; Female; Flutamide; Hirsutis | 2009 |
Hepatotoxicity during low-dose flutamide treatment for hirsutism.
Topics: Adult; Androgen Antagonists; Chemical and Drug Induced Liver Injury; Female; Flutamide; Hirsutism; H | 2009 |
Retrospective observational study on the effects and tolerability of flutamide in a large population of patients with various kinds of hirsutism over a 15-year period.
Topics: Female; Flutamide; Hirsutism; Humans; Retrospective Studies; Treatment Outcome | 2010 |
Therapy: Low-dose flutamide for hirsutism: into the limelight, at last.
Topics: Adult; Androgen Antagonists; Drug Administration Schedule; Female; Flutamide; Hirsutism; Humans; You | 2010 |
The treatment of polycystic ovary syndrome.
Topics: Adult; Androgen Antagonists; Cabergoline; Cardiovascular Diseases; Clomiphene; Cyproterone Acetate; | 2004 |
Serum prostate specific antigen levels in women with polycystic ovary syndrome and the effect of flutamide+desogestrel/ethinyl estradiol combination.
Topics: Adolescent; Adult; Androgen Antagonists; Androgens; Androstenedione; Contraceptives, Oral, Hormonal; | 2004 |
Hirsutism.
Topics: Androgen Antagonists; Contraceptives, Oral; Drug Therapy, Combination; Female; Flutamide; Hirsutism; | 2006 |
Flutamide hepatotoxicity.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combi | 1996 |
[Therapy of hirsutism with flutamide, a new non-steroidal antiandrogen].
Topics: Female; Flutamide; Hirsutism; Humans | 1994 |
Use of flutamide for self-induced androgen excess. A case report.
Topics: Adult; Clitoris; Edema; Female; Flutamide; Hirsutism; Humans; Hypertrophy; Paranoid Disorders; Testo | 1994 |
Flutamide and hirsutism.
Topics: Female; Flutamide; Hirsutism; Humans; Publishing | 1994 |
Safety of flutamide?
Topics: Chemical and Drug Induced Liver Injury; Female; Flutamide; Hirsutism; Humans; Male | 1994 |
The use of flutamide in the management of hirsutism.
Topics: Adolescent; Adult; Female; Flutamide; Hirsutism; Hormones; Humans; Polycystic Ovary Syndrome; Sex Ho | 1994 |
Hepatotoxicity complicating flutamide treatment of hirsutism.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Flutamide; Hirsutism; Humans | 1993 |
[Treatment of hirsutism].
Topics: Chemical and Drug Induced Liver Injury; Flutamide; Hirsutism; Humans; Risk Factors | 1994 |
The impact of a pure anti-androgen (flutamide) on LH, FSH, androgens and clinical status in idiopathic hirsutism.
Topics: Acne Vulgaris; Adult; Androgens; Dermatitis, Seborrheic; Female; Flutamide; Follicle Stimulating Hor | 1993 |
Flutamide--effects and side effects.
Topics: Adolescent; Adult; Female; Flutamide; Hirsutism; Humans | 1993 |
Prolonged treatment of hirsutism with flutamide alone in patients affected by polycystic ovary syndrome.
Topics: Adult; Androgen Antagonists; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutami | 1995 |
Successful treatment of hirsutism in HAIR-AN syndrome using flutamide, spironolactone, and birth control therapy.
Topics: Acanthosis Nigricans; Adolescent; Androgen Antagonists; Contraceptives, Oral, Combined; Contraceptiv | 1997 |
I've been trying to get rid of excess facial hair ever since I can remember. Is there any effective medication for this problem?
Topics: Androgen Antagonists; Female; Finasteride; Flutamide; Hirsutism; Humans | 1999 |
Fulminant liver failure associated with flutamide therapy for hirsutism.
Topics: Adolescent; Androgen Antagonists; Female; Flutamide; Hepatic Encephalopathy; Hirsutism; Humans; Live | 1999 |
[Toxic hepatitis caused by flutamide and hirsutism].
Topics: Adult; Androgen Antagonists; Chemical and Drug Induced Liver Injury; Female; Flutamide; Hirsutism; H | 2000 |
[Hirsutism, flutamide and hepatotoxicity].
Topics: Adult; Androgen Antagonists; Chemical and Drug Induced Liver Injury; Female; Flutamide; Hirsutism; H | 2001 |
Flutamide-induced hepatotoxicity: report of a case series.
Topics: Adolescent; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Chemical and Drug Induced Live | 2001 |
Testosterone-secreting gonadotropin-responsive adrenal adenoma and its treatment with the antiandrogen flutamide.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Androgen Antagonists; Chorionic Gonadotropin; Dexam | 2001 |
Treatment of hirsutism in women with flutamide.
Topics: Adult; Analysis of Variance; Androstane-3,17-diol; Androstenedione; Dehydroepiandrosterone; Dehydroe | 1992 |
Flutamide in the treatment of hirsutism.
Topics: Adolescent; Adult; Female; Flutamide; Hirsutism; Humans | 1991 |
[The effect of a peripheral androgenic blockade on plasma lipoproteins in hirsutism patients].
Topics: Adult; Alanine Transaminase; Analysis of Variance; Anovulation; Dehydroepiandrosterone; Drug Evaluat | 1990 |
Treatment of hirsutism with the pure antiandrogen flutamide.
Topics: Adult; Female; Flutamide; Gonadal Steroid Hormones; Hirsutism; Humans | 1990 |