Page last updated: 2024-10-27

flutamide and Fibrosis

flutamide has been researched along with Fibrosis in 4 studies

Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
"this study aims to explore the effect of androgen receptor (AR) blockade by flutamide on some renal pathologic changes such as inflammation, apoptosis, and fibrosis in male rats."8.31Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats. ( Abd Elaziz, AI; Allam, S; Amin, MM; Doghish, AS; El Shahat, RM; Elkady, MA; Elsakka, EGE; Hashish, AA; Ismail, A; Mohammed, OA; Mokhlis, HA; Sayed, SM; Yehia, AM, 2023)
"this study aims to explore the effect of androgen receptor (AR) blockade by flutamide on some renal pathologic changes such as inflammation, apoptosis, and fibrosis in male rats."4.31Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats. ( Abd Elaziz, AI; Allam, S; Amin, MM; Doghish, AS; El Shahat, RM; Elkady, MA; Elsakka, EGE; Hashish, AA; Ismail, A; Mohammed, OA; Mokhlis, HA; Sayed, SM; Yehia, AM, 2023)
" The use of HIFU in combination with androgen deprivation was associated with a decrease in numerical density of microvessels in zones of tumor and non-tumor parenchyma in patients with relapses."1.48Status of the Microcirculatory Network as a Factor of Prognosis and Evaluation of Therapeutic Efficiency in Prostate Cancer Treated by High-Intensity Focused Ultrasound in Combination with Androgen Deprivation. ( Abdullaev, NA; Bakarev, MA; Kachesov, IV; Levin, VP; Neimark, AI, 2018)
"In the current studies, we found that cardiac hypertrophy and fibrosis were significantly more pronounced in males compared with females of guanylyl cyclase-A knockout (GC-A KO) mice at 16 wk of age."1.32Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A. ( Adachi, Y; Fukamizu, A; Garbers, DL; Hamanaka, I; Harada, M; Izumi, T; Kawakami, R; Kishimoto, I; Kuwahara, K; Li, Y; Nakagawa, Y; Nakanishi, M; Nakao, K; Saito, Y; Takahashi, N; Tanimoto, K, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Allam, S1
Elsakka, EGE1
Ismail, A1
Doghish, AS1
Yehia, AM1
Elkady, MA1
Mokhlis, HA1
Sayed, SM1
Abd Elaziz, AI1
Hashish, AA1
Amin, MM1
El Shahat, RM1
Mohammed, OA1
Bakarev, MA1
Levin, VP1
Kachesov, IV1
Abdullaev, NA1
Neimark, AI1
de Alencar Franco Costa, D1
Todiras, M1
Campos, LA1
Cipolla-Neto, J1
Bader, M1
Baltatu, OC1
Li, Y1
Kishimoto, I1
Saito, Y1
Harada, M1
Kuwahara, K1
Izumi, T1
Hamanaka, I1
Takahashi, N1
Kawakami, R1
Tanimoto, K1
Nakagawa, Y1
Nakanishi, M1
Adachi, Y1
Garbers, DL1
Fukamizu, A1
Nakao, K1

Other Studies

4 other studies available for flutamide and Fibrosis

ArticleYear
Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats.
    Life sciences, 2023, Jun-15, Volume: 323

    Topics: Androgens; Animals; Apoptosis; Caspases; Fibrosis; Flutamide; Inflammation; Interleukin-6; Kidney Di

2023
Status of the Microcirculatory Network as a Factor of Prognosis and Evaluation of Therapeutic Efficiency in Prostate Cancer Treated by High-Intensity Focused Ultrasound in Combination with Androgen Deprivation.
    Bulletin of experimental biology and medicine, 2018, Volume: 165, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antigens, CD34; Antineoplastic Agents

2018
Sex-dependent differences in renal angiotensinogen as an early marker of diabetic nephropathy.
    Acta physiologica (Oxford, England), 2015, Volume: 213, Issue:3

    Topics: Albuminuria; Androgen Antagonists; Angiotensinogen; Animals; Biomarkers; Collagen Type I; Diabetes M

2015
Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A.
    Endocrinology, 2004, Volume: 145, Issue:2

    Topics: Androgen Receptor Antagonists; Androgens; Animals; Blood Pressure; Cardiomegaly; Female; Fibrosis; F

2004