flutamide has been researched along with Fibrosis in 4 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "this study aims to explore the effect of androgen receptor (AR) blockade by flutamide on some renal pathologic changes such as inflammation, apoptosis, and fibrosis in male rats." | 8.31 | Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats. ( Abd Elaziz, AI; Allam, S; Amin, MM; Doghish, AS; El Shahat, RM; Elkady, MA; Elsakka, EGE; Hashish, AA; Ismail, A; Mohammed, OA; Mokhlis, HA; Sayed, SM; Yehia, AM, 2023) |
| "this study aims to explore the effect of androgen receptor (AR) blockade by flutamide on some renal pathologic changes such as inflammation, apoptosis, and fibrosis in male rats." | 4.31 | Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats. ( Abd Elaziz, AI; Allam, S; Amin, MM; Doghish, AS; El Shahat, RM; Elkady, MA; Elsakka, EGE; Hashish, AA; Ismail, A; Mohammed, OA; Mokhlis, HA; Sayed, SM; Yehia, AM, 2023) |
| " The use of HIFU in combination with androgen deprivation was associated with a decrease in numerical density of microvessels in zones of tumor and non-tumor parenchyma in patients with relapses." | 1.48 | Status of the Microcirculatory Network as a Factor of Prognosis and Evaluation of Therapeutic Efficiency in Prostate Cancer Treated by High-Intensity Focused Ultrasound in Combination with Androgen Deprivation. ( Abdullaev, NA; Bakarev, MA; Kachesov, IV; Levin, VP; Neimark, AI, 2018) |
| "In the current studies, we found that cardiac hypertrophy and fibrosis were significantly more pronounced in males compared with females of guanylyl cyclase-A knockout (GC-A KO) mice at 16 wk of age." | 1.32 | Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A. ( Adachi, Y; Fukamizu, A; Garbers, DL; Hamanaka, I; Harada, M; Izumi, T; Kawakami, R; Kishimoto, I; Kuwahara, K; Li, Y; Nakagawa, Y; Nakanishi, M; Nakao, K; Saito, Y; Takahashi, N; Tanimoto, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allam, S | 1 |
| Elsakka, EGE | 1 |
| Ismail, A | 1 |
| Doghish, AS | 1 |
| Yehia, AM | 1 |
| Elkady, MA | 1 |
| Mokhlis, HA | 1 |
| Sayed, SM | 1 |
| Abd Elaziz, AI | 1 |
| Hashish, AA | 1 |
| Amin, MM | 1 |
| El Shahat, RM | 1 |
| Mohammed, OA | 1 |
| Bakarev, MA | 1 |
| Levin, VP | 1 |
| Kachesov, IV | 1 |
| Abdullaev, NA | 1 |
| Neimark, AI | 1 |
| de Alencar Franco Costa, D | 1 |
| Todiras, M | 1 |
| Campos, LA | 1 |
| Cipolla-Neto, J | 1 |
| Bader, M | 1 |
| Baltatu, OC | 1 |
| Li, Y | 1 |
| Kishimoto, I | 1 |
| Saito, Y | 1 |
| Harada, M | 1 |
| Kuwahara, K | 1 |
| Izumi, T | 1 |
| Hamanaka, I | 1 |
| Takahashi, N | 1 |
| Kawakami, R | 1 |
| Tanimoto, K | 1 |
| Nakagawa, Y | 1 |
| Nakanishi, M | 1 |
| Adachi, Y | 1 |
| Garbers, DL | 1 |
| Fukamizu, A | 1 |
| Nakao, K | 1 |
4 other studies available for flutamide and Fibrosis
| Article | Year |
|---|---|
Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats.
Topics: Androgens; Animals; Apoptosis; Caspases; Fibrosis; Flutamide; Inflammation; Interleukin-6; Kidney Di | 2023 |
Status of the Microcirculatory Network as a Factor of Prognosis and Evaluation of Therapeutic Efficiency in Prostate Cancer Treated by High-Intensity Focused Ultrasound in Combination with Androgen Deprivation.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antigens, CD34; Antineoplastic Agents | 2018 |
Sex-dependent differences in renal angiotensinogen as an early marker of diabetic nephropathy.
Topics: Albuminuria; Androgen Antagonists; Angiotensinogen; Animals; Biomarkers; Collagen Type I; Diabetes M | 2015 |
Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Blood Pressure; Cardiomegaly; Female; Fibrosis; F | 2004 |