flutamide has been researched along with Feminization in 7 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Feminization: Development of female secondary SEX CHARACTERISTICS in the MALE. It is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flutamide treatment or tfm mutation produced a significant attenuation of the development of hypertension." | 1.31 | Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse ren-2 gene. ( Andreev, D; Bader, M; Baltatu, O; Cayla, C; Iliescu, R; Jordan, C, 2002) |
| "True cryptorchidism occurred in 10% of cases, whereas 50% of testes descended to the scrotum and 40% were located in a suprainguinal ectopic region." | 1.30 | The effects of pre- and postnatal exposure to the nonsteroidal antiandrogen flutamide on testis descent and morphology in the Albino Swiss rat. ( Bennett, NK; Gilmore, DP; Kassim, NM; McDonald, SW; Payne, AP; Reid, O, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Schreiber, E | 1 |
| Garcia, T | 1 |
| González, N | 1 |
| Esplugas, R | 1 |
| Sharma, RP | 1 |
| Torrente, M | 1 |
| Kumar, V | 1 |
| Bovee, T | 1 |
| Katsanou, ES | 1 |
| Machera, K | 1 |
| Domingo, JL | 1 |
| Gómez, M | 1 |
| Baltatu, O | 1 |
| Cayla, C | 1 |
| Iliescu, R | 1 |
| Andreev, D | 1 |
| Jordan, C | 1 |
| Bader, M | 1 |
| Filby, AL | 1 |
| Thorpe, KL | 1 |
| Maack, G | 1 |
| Tyler, CR | 1 |
| Scott, HM | 1 |
| Hutchison, GR | 1 |
| Mahood, IK | 1 |
| Hallmark, N | 1 |
| Welsh, M | 1 |
| De Gendt, K | 1 |
| Verhoeven, G | 1 |
| O'Shaughnessy, P | 1 |
| Sharpe, RM | 1 |
| Brooks, JR | 1 |
| Berman, C | 1 |
| Hichens, M | 1 |
| Primka, RL | 1 |
| Reynolds, GF | 1 |
| Rasmusson, GH | 1 |
| Kassim, NM | 1 |
| McDonald, SW | 1 |
| Reid, O | 1 |
| Bennett, NK | 1 |
| Gilmore, DP | 1 |
| Payne, AP | 1 |
| Kledal, TJ | 1 |
| Rajpert-De Meyts, E | 1 |
| Skakkebaek, NE | 1 |
| Jørgensen, KD | 1 |
7 other studies available for flutamide and Feminization
| Article | Year |
|---|---|
Maternal exposure to mixtures of dienestrol, linuron and flutamide. Part I: Feminization effects on male rat offspring.
Topics: Animals; Animals, Newborn; Cryptorchidism; Dienestrol; Dose-Response Relationship, Drug; Endpoint De | 2020 |
Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse ren-2 gene.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Animals; Animals, Genetically Modified; Blood P | 2002 |
Gene expression profiles revealing the mechanisms of anti-androgen- and estrogen-induced feminization in fish.
Topics: Androgen Antagonists; Animals; Cyprinidae; Ethinyl Estradiol; Female; Feminization; Flutamide; Gene | 2007 |
Role of androgens in fetal testis development and dysgenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androgen Antagonists; Animals; Body Weight; Carcinogens; Dibutyl P | 2007 |
Biological activities of a new steroidal inhibitor of delta 4-5 alpha-reductase.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Azasteroids; Body Weig | 1982 |
The effects of pre- and postnatal exposure to the nonsteroidal antiandrogen flutamide on testis descent and morphology in the Albino Swiss rat.
Topics: Androgen Antagonists; Animals; Cryptorchidism; Feminization; Flutamide; Gestational Age; Male; Rats; | 1997 |
A dose-finding study of in utero and lactational exposure to diethylstilboestrol and flutamide in 129/Sv mice.
Topics: Androgen Antagonists; Animals; Diethylstilbestrol; Estrogens, Non-Steroidal; Female; Feminization; F | 2000 |