flutamide has been researched along with Dyskeratosis Congenita in 1 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Dyskeratosis Congenita: A predominantly X-linked recessive syndrome characterized by a triad of reticular skin pigmentation, nail dystrophy and leukoplakia of mucous membranes. Oral and dental abnormalities may also be present. Complications are a predisposition to malignancy and bone marrow involvement with pancytopenia. (from Int J Paediatr Dent 2000 Dec;10(4):328-34) The X-linked form is also known as Zinsser-Cole-Engman syndrome and involves the gene which encodes a highly conserved protein called dyskerin.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calado, RT | 1 |
| Yewdell, WT | 1 |
| Wilkerson, KL | 1 |
| Regal, JA | 1 |
| Kajigaya, S | 1 |
| Stratakis, CA | 1 |
| Young, NS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Low Dose Danazol for the Treatment of Telomere Related Diseases[NCT03312400] | Phase 2 | 40 participants (Anticipated) | Interventional | 2018-02-08 | Recruiting | ||
| Male Hormones for Telomere Related Diseases[NCT02055456] | Phase 1/Phase 2 | 20 participants (Actual) | Interventional | 2014-02-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for flutamide and Dyskeratosis Congenita
| Article | Year |
|---|---|
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anemia, Aplastic; Aromatase Inhibito | 2009 |
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anemia, Aplastic; Aromatase Inhibito | 2009 |
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anemia, Aplastic; Aromatase Inhibito | 2009 |
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anemia, Aplastic; Aromatase Inhibito | 2009 |