flutamide has been researched along with Cholestasis in 5 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cholestasis is one of the major causes of drug-induced liver injury (DILI), which can result in withdrawal of approved drugs from the market." | 1.46 | Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics. ( Honda, H; Ito, Y; Kawamoto, T; Morita, O, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dawson, S | 1 |
| Stahl, S | 1 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 1 |
| Kawamoto, T | 1 |
| Ito, Y | 1 |
| Morita, O | 1 |
| Honda, H | 1 |
| Prattichizzo, FA | 1 |
| Lee, HW | 1 |
| Chung, JP | 1 |
| Lee, KS | 2 |
| Kim, KC | 1 |
| Chon, CY | 1 |
| Park, IS | 1 |
| Kim, HG | 1 |
| Hart, W | 1 |
| Stricker, BH | 1 |
5 other studies available for flutamide and Cholestasis
| Article | Year |
|---|---|
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics.
Topics: Administration, Oral; Animals; Chlorpromazine; Cholestasis; Cholesterol; Cyclosporine; Diclofenac; D | 2017 |
Acute cholestatic hepatitis secondary to flutamide therapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Cholestasis; Flutami | 1994 |
A case of flutamide-induced acute cholestatic hepatitis--a case report.
Topics: Acute Disease; Aged; Androgen Antagonists; Chemical and Drug Induced Liver Injury; Cholestasis; Flut | 1996 |
Flutamide and hepatitis.
Topics: Aged; Anilides; Chemical and Drug Induced Liver Injury; Cholestasis; Flutamide; Humans; Male | 1989 |