flutamide has been researched along with Cholestasis in 5 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
Excerpt | Relevance | Reference |
---|---|---|
"Cholestasis is one of the major causes of drug-induced liver injury (DILI), which can result in withdrawal of approved drugs from the market." | 1.46 | Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics. ( Honda, H; Ito, Y; Kawamoto, T; Morita, O, 2017) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (20.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Dawson, S | 1 |
Stahl, S | 1 |
Paul, N | 1 |
Barber, J | 1 |
Kenna, JG | 1 |
Kawamoto, T | 1 |
Ito, Y | 1 |
Morita, O | 1 |
Honda, H | 1 |
Prattichizzo, FA | 1 |
Lee, HW | 1 |
Chung, JP | 1 |
Lee, KS | 2 |
Kim, KC | 1 |
Chon, CY | 1 |
Park, IS | 1 |
Kim, HG | 1 |
Hart, W | 1 |
Stricker, BH | 1 |
5 other studies available for flutamide and Cholestasis
Article | Year |
---|---|
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics.
Topics: Administration, Oral; Animals; Chlorpromazine; Cholestasis; Cholesterol; Cyclosporine; Diclofenac; D | 2017 |
Acute cholestatic hepatitis secondary to flutamide therapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Cholestasis; Flutami | 1994 |
A case of flutamide-induced acute cholestatic hepatitis--a case report.
Topics: Acute Disease; Aged; Androgen Antagonists; Chemical and Drug Induced Liver Injury; Cholestasis; Flut | 1996 |
Flutamide and hepatitis.
Topics: Aged; Anilides; Chemical and Drug Induced Liver Injury; Cholestasis; Flutamide; Humans; Male | 1989 |