flutamide has been researched along with Cholestasis, Intrahepatic in 3 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Cholestasis, Intrahepatic: Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "When flutamide was administered to rats as a single oral dose of 100 mg/kg, the biliary excretion rate of bolus-injected [3H]TCA was decreased and the liver tissue concentration of flutamide exceeded 50 microM." | 1.34 | Involvement of bile salt export pump in flutamide-induced cholestatic hepatitis. ( Iwanaga, T; Maeda, T; Nakakariya, M; Tamai, I; Yabuuchi, H, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwanaga, T | 1 |
| Nakakariya, M | 1 |
| Yabuuchi, H | 1 |
| Maeda, T | 1 |
| Tamai, I | 1 |
| Rosman, AS | 1 |
| Frissora-Rodeo, C | 1 |
| Marshall, AT | 1 |
| Reiter, BP | 1 |
| Paronetto, F | 1 |
| Mena, FJ | 1 |
| Goyeneche, ML | 1 |
| Velicia, R | 1 |
| González, JM | 1 |
| Bellido, J | 1 |
| Caro-Patón, A | 1 |
3 other studies available for flutamide and Cholestasis, Intrahepatic
| Article | Year |
|---|---|
Involvement of bile salt export pump in flutamide-induced cholestatic hepatitis.
Topics: Androgen Antagonists; Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cells, Cultu | 2007 |
Cholestatic hepatitis following flutamide.
Topics: Adenocarcinoma; Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Flutamide; | 1993 |
[Acute cholestatic hepatitis secondary to flutamide].
Topics: Acute Disease; Aged; Androgen Antagonists; Chemical and Drug Induced Liver Injury; Cholestasis, Intr | 1998 |