flutamide has been researched along with Cardiomegaly in 1 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the current studies, we found that cardiac hypertrophy and fibrosis were significantly more pronounced in males compared with females of guanylyl cyclase-A knockout (GC-A KO) mice at 16 wk of age." | 1.32 | Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A. ( Adachi, Y; Fukamizu, A; Garbers, DL; Hamanaka, I; Harada, M; Izumi, T; Kawakami, R; Kishimoto, I; Kuwahara, K; Li, Y; Nakagawa, Y; Nakanishi, M; Nakao, K; Saito, Y; Takahashi, N; Tanimoto, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Kishimoto, I | 1 |
| Saito, Y | 1 |
| Harada, M | 1 |
| Kuwahara, K | 1 |
| Izumi, T | 1 |
| Hamanaka, I | 1 |
| Takahashi, N | 1 |
| Kawakami, R | 1 |
| Tanimoto, K | 1 |
| Nakagawa, Y | 1 |
| Nakanishi, M | 1 |
| Adachi, Y | 1 |
| Garbers, DL | 1 |
| Fukamizu, A | 1 |
| Nakao, K | 1 |
1 other study available for flutamide and Cardiomegaly
| Article | Year |
|---|---|
Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Blood Pressure; Cardiomegaly; Female; Fibrosis; F | 2004 |