flutamide has been researched along with Cardiac Hypertrophy in 1 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the current studies, we found that cardiac hypertrophy and fibrosis were significantly more pronounced in males compared with females of guanylyl cyclase-A knockout (GC-A KO) mice at 16 wk of age." | 1.32 | Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A. ( Adachi, Y; Fukamizu, A; Garbers, DL; Hamanaka, I; Harada, M; Izumi, T; Kawakami, R; Kishimoto, I; Kuwahara, K; Li, Y; Nakagawa, Y; Nakanishi, M; Nakao, K; Saito, Y; Takahashi, N; Tanimoto, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Kishimoto, I | 1 |
| Saito, Y | 1 |
| Harada, M | 1 |
| Kuwahara, K | 1 |
| Izumi, T | 1 |
| Hamanaka, I | 1 |
| Takahashi, N | 1 |
| Kawakami, R | 1 |
| Tanimoto, K | 1 |
| Nakagawa, Y | 1 |
| Nakanishi, M | 1 |
| Adachi, Y | 1 |
| Garbers, DL | 1 |
| Fukamizu, A | 1 |
| Nakao, K | 1 |
1 other study available for flutamide and Cardiac Hypertrophy
| Article | Year |
|---|---|
Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Blood Pressure; Cardiomegaly; Female; Fibrosis; F | 2004 |