Page last updated: 2024-10-27

flutamide and Bone Loss, Osteoclastic

flutamide has been researched along with Bone Loss, Osteoclastic in 5 studies

Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Research Excerpts

ExcerptRelevanceReference
"Ninety-five patients with prostate cancer were divided into one of three groups: 26 patients with bone metastasis (BM(+)), 35 patients without bone metastasis on nonhormonal therapy (BM(-)HT(-)) and 34 patients without bone metastasis on hormonal therapy (BM(-)HT(+))."1.31Biochemical markers for the detection of bone metastasis in patients with prostate cancer: diagnostic efficacy and the effect of hormonal therapy. ( Fukunaga, M; Jo, Y; Sone, T; Tamada, T; Tanaka, H; Tomomitsu, T, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Michael, H1
Härkönen, PL1
Väänänen, HK1
Hentunen, TA1
Gallagher, AC1
Chambers, TJ1
Tobias, JH1
Pederson, L1
Kremer, M1
Judd, J1
Pascoe, D1
Spelsberg, TC1
Riggs, BL1
Oursler, MJ1
Moghetti, P1
Castello, R1
Zamberlan, N1
Rossini, M1
Gatti, D1
Negri, C1
Tosi, F1
Muggeo, M1
Adami, S1
Tamada, T1
Sone, T1
Tomomitsu, T1
Jo, Y1
Tanaka, H1
Fukunaga, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Denosumab Versus Zoledronic Acid for Patients With Beta-Thalassemia Major-Induced Osteoporosis[NCT03040765]Phase 317 participants (Actual)Interventional2018-05-14Terminated (stopped due to failed to recruit eligible subjects)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for flutamide and Bone Loss, Osteoclastic

ArticleYear
Spironolactone, but not flutamide, administration prevents bone loss in hyperandrogenic women treated with gonadotropin-releasing hormone agonist.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:4

    Topics: Adult; Bone and Bones; Bone Density; Bone Resorption; Female; Flutamide; Hirsutism; Humans; Polycyst

1999

Other Studies

4 other studies available for flutamide and Bone Loss, Osteoclastic

ArticleYear
Estrogen and testosterone use different cellular pathways to inhibit osteoclastogenesis and bone resorption.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:12

    Topics: Acid Phosphatase; Adult; Androgen Antagonists; Animals; Bone Resorption; Carrier Proteins; Cattle; C

2005
Androgens contribute to the stimulation of cancellous bone formation by ovarian hormones in female rats.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Animals; Body Weight; Bone and Bones; Bone Resorption; Dihydrotestosterone; Diphosphonates; Female;

1996
Androgens regulate bone resorption activity of isolated osteoclasts in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jan-19, Volume: 96, Issue:2

    Topics: Acid Phosphatase; Androgen Antagonists; Androgens; Animals; Bone Resorption; Cathepsin B; Chickens;

1999
Biochemical markers for the detection of bone metastasis in patients with prostate cancer: diagnostic efficacy and the effect of hormonal therapy.
    Journal of bone and mineral metabolism, 2001, Volume: 19, Issue:1

    Topics: Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, T

2001