flutamide has been researched along with Alzheimer Disease in 2 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cognitive dysfunction is known to be influenced by circulating sex steroidal hormones." | 1.43 | Protective effects of testosterone on cognitive dysfunction in Alzheimer's disease model rats induced by oligomeric beta amyloid peptide 1-42. ( Huo, DS; Jia, JX; Sun, JF; Wang, H; Yan, XS; Yang, ZJ; Zhang, B, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huo, DS | 1 |
| Sun, JF | 1 |
| Zhang, B | 1 |
| Yan, XS | 1 |
| Wang, H | 1 |
| Jia, JX | 1 |
| Yang, ZJ | 1 |
| Gandy, S | 1 |
| Almeida, OP | 1 |
| Fonte, J | 1 |
| Lim, D | 1 |
| Waterrus, A | 1 |
| Spry, N | 1 |
| Flicker, L | 1 |
| Martins, RN | 1 |
2 other studies available for flutamide and Alzheimer Disease
| Article | Year |
|---|---|
Protective effects of testosterone on cognitive dysfunction in Alzheimer's disease model rats induced by oligomeric beta amyloid peptide 1-42.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Androgen Antagonists; Animals; Cognitive Dysfunction; Flut | 2016 |
Chemical andropause and amyloid-beta peptide.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Androgen Antagoni | 2001 |