flutamide has been researched along with Alopecia in 14 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Alopecia: Absence of hair from areas where it is normally present.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical hydroalcoholic solution of flutamide plus minoxidil may be promising treatment for the androgenetic alopecia." | 9.51 | Comparison between "5% minoxidil plus 2% flutamide" solution vs. "5% minoxidil" solution in the treatment of androgenetic alopecia. ( Faghihi, G; Hoseyni, MS; Iraji, F; Jelvan, M; Saber, M; Siadat, AH, 2022) |
| "Flutamide is a potent anti-androgen with the several unwanted side effects in systemic administration, therefore, it has attracted special interest in the development of topically applied formulations for the treatment of androgenic alopecia." | 7.83 | Histological assessment of follicular delivery of flutamide by solid lipid nanoparticles: potential tool for the treatment of androgenic alopecia. ( Adib, ZM; Ghanbarzadeh, S; Hamishehkar, H; Javadzadeh, Y; Kouhsoltani, M; Sepehran, S, 2016) |
| "Topical hydroalcoholic solution of flutamide plus minoxidil may be promising treatment for the androgenetic alopecia." | 5.51 | Comparison between "5% minoxidil plus 2% flutamide" solution vs. "5% minoxidil" solution in the treatment of androgenetic alopecia. ( Faghihi, G; Hoseyni, MS; Iraji, F; Jelvan, M; Saber, M; Siadat, AH, 2022) |
| "Flutamide at a dose of 250 mg daily induced a modest improvement in alopecia after 1 year, whereas cyproterone acetate and finasteride were not effective." | 5.10 | Treatment of hyperandrogenic alopecia in women. ( Carmina, E; Lobo, RA, 2003) |
| "Flutamide is a potent anti-androgen with the several unwanted side effects in systemic administration, therefore, it has attracted special interest in the development of topically applied formulations for the treatment of androgenic alopecia." | 3.83 | Histological assessment of follicular delivery of flutamide by solid lipid nanoparticles: potential tool for the treatment of androgenic alopecia. ( Adib, ZM; Ghanbarzadeh, S; Hamishehkar, H; Javadzadeh, Y; Kouhsoltani, M; Sepehran, S, 2016) |
| "Both groups showed a marked decrease in alopecia scores after 12 months of flutamide therapy, compared with baseline values." | 3.77 | Prospective cohort study on the effects and tolerability of flutamide in patients with female pattern hair loss. ( Battaglia, C; Fabbri, R; Paradisi, R; Porcu, E; Seracchioli, R; Venturoli, S, 2011) |
| "Common types of nonscarring hair loss, including female pattern hair loss and telogen effluvium, may be diagnosed and managed by the obstetrician/gynecologist." | 2.52 | Hair loss in women. ( Bechtel, MA; Harfmann, KL, 2015) |
| "Female pattern hair loss, or female pattern androgenetic alopecia, is a nonscarring alopecia with a multi-factorial etiology that mostly affects postmenopausal women and is characterized by a reduction in hair density over the crown and frontal scalp." | 2.52 | Female pattern hair loss. ( Ioannides, D; Lazaridou, E, 2015) |
| "Flutamide was found to be more effective than spironolactone or cyproterone in one study." | 2.44 | A review of hormonal therapy for female pattern (androgenic) alopecia. ( Scheinfeld, N, 2008) |
| "Although hirsutism and androgenetic alopecia are cosmetic problems, they can be psychologically devastating for women." | 2.40 | Antiandrogen treatment of polycystic ovary syndrome. ( Rittmaster, RS, 1999) |
| "Female pattern hair loss is a common but difficult to manage condition." | 1.37 | Treatment of female pattern hair loss with the androgen receptor antagonist flutamide. ( Sinclair, R; Yazdabadi, A, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Faghihi, G | 1 |
| Iraji, F | 1 |
| Siadat, AH | 1 |
| Saber, M | 1 |
| Jelvan, M | 1 |
| Hoseyni, MS | 1 |
| Azarchi, S | 1 |
| Bienenfeld, A | 1 |
| Lo Sicco, K | 1 |
| Marchbein, S | 1 |
| Shapiro, J | 1 |
| Nagler, AR | 1 |
| Buzney, E | 1 |
| Sheu, J | 1 |
| Buzney, C | 1 |
| Reynolds, RV | 1 |
| Harfmann, KL | 1 |
| Bechtel, MA | 1 |
| Hamishehkar, H | 1 |
| Ghanbarzadeh, S | 1 |
| Sepehran, S | 1 |
| Javadzadeh, Y | 1 |
| Adib, ZM | 1 |
| Kouhsoltani, M | 1 |
| Ioannides, D | 1 |
| Lazaridou, E | 1 |
| Scheinfeld, N | 1 |
| Crabtree, JS | 1 |
| Kilbourne, EJ | 1 |
| Peano, BJ | 1 |
| Chippari, S | 1 |
| Kenney, T | 1 |
| McNally, C | 1 |
| Wang, W | 1 |
| Harris, HA | 1 |
| Winneker, RC | 1 |
| Nagpal, S | 1 |
| Thompson, CC | 1 |
| Walker, WH | 1 |
| Paradisi, R | 1 |
| Porcu, E | 1 |
| Fabbri, R | 1 |
| Seracchioli, R | 1 |
| Battaglia, C | 1 |
| Venturoli, S | 1 |
| Yazdabadi, A | 1 |
| Sinclair, R | 1 |
| Carmina, E | 1 |
| Lobo, RA | 1 |
| Rittmaster, RS | 1 |
| Sintov, A | 1 |
| Serafimovich, S | 1 |
| Gilhar, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluating PAI-1 Expression in the Hair Follicles of Patients With Non-scarring Hair Loss.[NCT02548689] | 10 participants (Actual) | Observational | 2015-07-31 | Terminated (stopped due to Original lead investigator left Northwestern University) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for flutamide and Alopecia
| Article | Year |
|---|---|
Androgens in women: Hormone-modulating therapies for skin disease.
Topics: 5-alpha Reductase Inhibitors; Acne Vulgaris; Adrenal Hyperplasia, Congenital; Alopecia; Androgen Ant | 2019 |
Polycystic ovary syndrome: a review for dermatologists: Part II. Treatment.
Topics: 5-alpha Reductase Inhibitors; Acne Vulgaris; Alopecia; Androgen Antagonists; Contraceptives, Oral, C | 2014 |
Hair loss in women.
Topics: 5-alpha Reductase Inhibitors; Alopecia; Androgen Antagonists; Female; Finasteride; Flutamide; Hair; | 2015 |
Female pattern hair loss.
Topics: 5-alpha Reductase Inhibitors; Administration, Cutaneous; Alopecia; Androgen Antagonists; Androgen Re | 2015 |
A review of hormonal therapy for female pattern (androgenic) alopecia.
Topics: 5-alpha Reductase Inhibitors; Alopecia; Androgen Antagonists; Androgens; Cyproterone Acetate; Dermat | 2008 |
Antiandrogen treatment of polycystic ovary syndrome.
Topics: Alopecia; Androgen Antagonists; Androgens; Cyproterone Acetate; Female; Finasteride; Flutamide; Hirs | 1999 |
2 trials available for flutamide and Alopecia
| Article | Year |
|---|---|
Comparison between "5% minoxidil plus 2% flutamide" solution vs. "5% minoxidil" solution in the treatment of androgenetic alopecia.
Topics: Administration, Topical; Alopecia; Finasteride; Flutamide; Humans; Minoxidil; Treatment Outcome | 2022 |
Treatment of hyperandrogenic alopecia in women.
Topics: 5-alpha Reductase Inhibitors; Adult; Alopecia; Androgen Antagonists; Cyproterone Acetate; Dehydroepi | 2003 |
6 other studies available for flutamide and Alopecia
| Article | Year |
|---|---|
Histological assessment of follicular delivery of flutamide by solid lipid nanoparticles: potential tool for the treatment of androgenic alopecia.
Topics: Administration, Cutaneous; Alopecia; Androgen Antagonists; Animals; Chemistry, Pharmaceutical; Drug | 2016 |
A mouse model of androgenetic alopecia.
Topics: Alopecia; Androgen Antagonists; Androgens; Animals; beta Catenin; Blotting, Western; Cell Line; Cell | 2010 |
Is the "comb over" dying? A mouse model for male pattern baldness (androgenic alopecia).
Topics: Alopecia; Androgen Antagonists; Androgens; Animals; beta Catenin; Dihydrotestosterone; Disease Model | 2010 |
Prospective cohort study on the effects and tolerability of flutamide in patients with female pattern hair loss.
Topics: Adolescent; Adult; Alopecia; Androgen Antagonists; Cohort Studies; Contraceptives, Oral; Female; Flu | 2011 |
Treatment of female pattern hair loss with the androgen receptor antagonist flutamide.
Topics: Adult; Alopecia; Androgen Receptor Antagonists; Drug Therapy, Combination; Female; Flutamide; Hair; | 2011 |
New topical antiandrogenic formulations can stimulate hair growth in human bald scalp grafted onto mice.
Topics: Administration, Topical; Alopecia; Androgen Antagonists; Animals; Finasteride; Flutamide; Hair Folli | 2000 |