Page last updated: 2024-10-27

flutamide and Aggression

flutamide has been researched along with Aggression in 26 studies

Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
" We examined the role of ARs in regulating territorial aggression in captive song sparrows under short- and long-day conditions as well as just prior to, and at the start of the breading season in freely living birds using the nonsteroidal antiandrogen flutamide to block AR function."3.76The role of androgen receptors in regulating territorial aggression in male song sparrows. ( Sperry, TS; Wacker, DW; Wingfield, JC, 2010)
"ATD+flutamide treatment decreased several aggressive behaviors."1.30Combined aromatase inhibitor and antiandrogen treatment decreases territorial aggression in a wild songbird during the nonbreeding season. ( Soma, KK; Sullivan, K; Wingfield, J, 1999)
"Flutamide did not inhibit aggressive or sexual behavior, but did decrease testis weight as well as the size of the renal sex segment."1.27Effects of the antiandrogens cyproterone acetate and flutamide on male reproductive behavior in a lizard (Anolis sagrei). ( Tokarz, RR, 1987)
" While chronic administration of MT to castrate isolated mice returned the incidence of fighting behavior to control values, chronic administration of FTA + MTdid not significantly reduce the incidence of fighting as compared to castrate + MT values."1.26Resistance of androgen-mediated aggressive behavior in mice to flutamide, an antiandrogen. ( Brugmans, M; DaVanzo, JP; Greenslade, FC; Heilman, RD, 1976)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19905 (19.23)18.7374
1990's6 (23.08)18.2507
2000's4 (15.38)29.6817
2010's10 (38.46)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Drea, CM2
Davies, CS1
Greene, LK2
Mitchell, J1
Blondel, DV1
Shearer, CL1
Feldblum, JT1
Dimac-Stohl, KA1
Smyth-Kabay, KN1
Clutton-Brock, TH1
Cunha, AAP1
Partridge, CG1
Knapp, R2
Neff, BD2
Vullioud, P1
Bshary, R1
Ros, AF1
delBarco-Trillo, J1
Goncalves, IB1
Fenkes, M1
Wisse, JH1
Drewe, JA1
Manser, MB1
Clutton-Brock, T1
Bethea, CL1
Belikova, Y1
Phu, K1
Mammerella, G1
Sperry, TS1
Wacker, DW1
Wingfield, JC3
Kramer, KM1
Perry, AN1
Golbin, D1
Cushing, BS1
Marasco, V1
Fusani, L1
Dessì-Fulgheri, F1
Canoine, V2
Ręk, P1
Osiejuk, TS1
Budka, M1
Robinson, S1
Penatti, CA1
Clark, AS1
Rodgers, CM1
van Breukelen, NA1
Moore, IT1
Walker, BG1
Tomaszycki, ML1
Banerjee, SB1
Adkins-Regan, E1
Taylor, GT1
Haller, J1
Rupich, R1
Weiss, J1
Clark, CR1
Nowell, NW1
Searcy, WA1
Vleck, CM1
Dobrott, SJ1
Orengo, CA1
Kunik, ME1
Ghusn, H1
Yudofsky, SC1
Altemus, M1
Greenberg, BD1
Keuler, D1
Jacobson, KR1
Murphy, DL1
Soma, KK1
Sullivan, K1
Wingfield, J1
Gwinner, E1
Heilman, RD1
Brugmans, M1
Greenslade, FC1
DaVanzo, JP1
Schwabl, H1
Kriner, E1
Schlinger, BA1
Callard, GV1
Tokarz, RR1

Trials

2 trials available for flutamide and Aggression

ArticleYear
Reproductive steroid receptors and actions in the locus coeruleus of male macaques: Part of an aggression circuit?
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 11-03, Volume: 71

    Topics: Aggression; Androgen Antagonists; Androgens; Animals; Corticotropin-Releasing Hormone; Dihydrotestos

2016
Open trial of flutamide for treatment of obsessive-compulsive disorder.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:7

    Topics: Adult; Aggression; Ambulatory Care; Androgen Antagonists; Androgen Receptor Antagonists; Female; Flu

1999

Other Studies

24 other studies available for flutamide and Aggression

ArticleYear
An intergenerational androgenic mechanism of female intrasexual competition in the cooperatively breeding meerkat.
    Nature communications, 2021, 12-17, Volume: 12, Issue:1

    Topics: Aggression; Androgen Antagonists; Androgens; Animals; Animals, Newborn; Animals, Wild; Breeding; Com

2021
Androgen and prolactin manipulation induces changes in aggressive and nurturing behavior in a fish with male parental care.
    Hormones and behavior, 2019, Volume: 116

    Topics: Aggression; Androgens; Animals; Bromocriptine; Fishes; Flutamide; Larva; Male; Nesting Behavior; Pat

2019
Intra- and interspecific aggression do not modulate androgen levels in dusky gregories, yet male aggression is reduced by an androgen blocker.
    Hormones and behavior, 2013, Volume: 64, Issue:3

    Topics: Aggression; Androgen Receptor Antagonists; Androgens; Animals; Behavior, Animal; Escape Reaction; Fe

2013
Beyond aggression: Androgen-receptor blockade modulates social interaction in wild meerkats.
    Hormones and behavior, 2016, Volume: 78

    Topics: Aggression; Androgen Receptor Antagonists; Animals; Behavior, Animal; Dominance-Subordination; Femal

2016
The role of androgen receptors in regulating territorial aggression in male song sparrows.
    Hormones and behavior, 2010, Volume: 57, Issue:1

    Topics: Aggression; Androgen Antagonists; Animals; Circadian Rhythm; Flutamide; Male; Photoperiod; Receptors

2010
Sex steroids are necessary in the second postnatal week for the expression of male alloparental behavior in prairie voles (Microtus ochragaster).
    Behavioral neuroscience, 2009, Volume: 123, Issue:5

    Topics: Aggression; Analysis of Variance; Androgen Antagonists; Androstatrienes; Animals; Animals, Newborn;

2009
Non-migratory stonechats show seasonal changes in the hormonal regulation of non-seasonal territorial aggression.
    Hormones and behavior, 2011, Volume: 60, Issue:4

    Topics: Aggression; Androgen Antagonists; Animal Migration; Animals; Aromatase Inhibitors; Behavior, Animal;

2011
Functionally similar acoustic signals in the corncrake (Crex crex) transmit information about different states of the sender during aggressive interactions.
    Hormones and behavior, 2011, Volume: 60, Issue:5

    Topics: Aggression; Androgen Antagonists; Animals; Birds; Flutamide; Male; Testosterone; Vocalization, Anima

2011
The role of the androgen receptor in anabolic androgenic steroid-induced aggressive behavior in C57BL/6J and Tfm mice.
    Hormones and behavior, 2012, Volume: 61, Issue:1

    Topics: Aggression; Anabolic Agents; Androgen Receptor Antagonists; Androgen-Insensitivity Syndrome; Animals

2012
Androgen-mediated nurturing and aggressive behaviors during paternal care in bluegill sunfish (Lepomis macrochirus).
    Hormones and behavior, 2013, Volume: 63, Issue:3

    Topics: Aggression; Androgen Antagonists; Androgens; Animals; Drug Implants; Flutamide; Male; Nesting Behavi

2013
Androgen receptor antagonist impairs courtship but not aggressive behavior in the monogamous cichlid, Amatitlania nigrofasciata.
    Hormones and behavior, 2013, Volume: 63, Issue:3

    Topics: Aggression; Androgen Receptor Antagonists; Animals; Cichlids; Courtship; Drug Implants; Female; Flut

2013
The effects of combined aromatase inhibitor and anti-androgen on male territorial aggression in a tropical population of rufous-collared sparrows, Zonotrichia capensis.
    General and comparative endocrinology, 2004, Jan-15, Volume: 135, Issue:2

    Topics: Aggression; Androgen Antagonists; Androstatrienes; Animals; Aromatase Inhibitors; Corticosterone; Di

2004
The role of sex steroids in courtship, pairing and pairing behaviors in the socially monogamous zebra finch.
    Hormones and behavior, 2006, Volume: 50, Issue:1

    Topics: Aggression; Androgen Antagonists; Androstatrienes; Animals; Aromatase; Aromatase Inhibitors; Courtsh

2006
Testicular hormones and intermale aggressive behaviour in the presence of a female rat.
    The Journal of endocrinology, 1984, Volume: 100, Issue:3

    Topics: Aggression; Androgen Antagonists; Animals; Castration; Estrus; Female; Flutamide; Male; Pregnancy; R

1984
The effect of the non-steroidal antiandrogen flutamide on neural receptor binding of testosterone and intermale aggressive behavior in mice.
    Psychoneuroendocrinology, 1980, Volume: 5, Issue:1

    Topics: Aggression; Anilides; Animals; Cytosol; Flutamide; Humans; Hypothalamus; In Vitro Techniques; Male;

1980
The effects of androgen and antiandrogen on dominance and aggressiveness in male red-winged blackbirds.
    Hormones and behavior, 1980, Volume: 14, Issue:2

    Topics: Aggression; Anilides; Animals; Birds; Cholesterol; Dihydrotestosterone; Drug Implants; Flutamide; Hu

1980
Testosterone, antiandrogen, and alloparental behavior in bobwhite quail foster fathers.
    Hormones and behavior, 1993, Volume: 27, Issue:1

    Topics: Aggression; Androgen Antagonists; Androstatrienes; Animals; Colinus; Drug Implants; Drug Therapy, Co

1993
Correlation of testosterone with aggression in demented elderly men.
    The Journal of nervous and mental disease, 1997, Volume: 185, Issue:5

    Topics: Age Factors; Aged; Aggression; Androgen Antagonists; Dementia; Flutamide; Humans; Leuprolide; Male;

1997
Combined aromatase inhibitor and antiandrogen treatment decreases territorial aggression in a wild songbird during the nonbreeding season.
    General and comparative endocrinology, 1999, Volume: 115, Issue:3

    Topics: Aggression; Androgen Antagonists; Androgen Receptor Antagonists; Animals; Aromatase Inhibitors; Beha

1999
Seasonal differences in the hormonal control of territorial aggression in free-living European stonechats.
    Hormones and behavior, 2002, Volume: 41, Issue:1

    Topics: Aggression; Androgen Antagonists; Androstatrienes; Animals; Enzyme Inhibitors; Estrogens; Europe; Fl

2002
Resistance of androgen-mediated aggressive behavior in mice to flutamide, an antiandrogen.
    Psychopharmacology, 1976, May-05, Volume: 47, Issue:1

    Topics: Aggression; Anilides; Animals; Castration; Flutamide; Humans; Male; Methyltestosterone; Mice; Organ

1976
Territorial aggression and song of male European robins (Erithacus rubecula) in autumn and spring: effects of antiandrogen treatment.
    Hormones and behavior, 1991, Volume: 25, Issue:2

    Topics: Aggression; Androgen Antagonists; Animals; Birds; Flutamide; Male; Seasons; Territoriality; Testoste

1991
Aromatization mediates aggressive behavior in quail.
    General and comparative endocrinology, 1990, Volume: 79, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Aggression; Androstenedione; Animals; Aromatase; Aromatase Inhibitors;

1990
Effects of the antiandrogens cyproterone acetate and flutamide on male reproductive behavior in a lizard (Anolis sagrei).
    Hormones and behavior, 1987, Volume: 21, Issue:1

    Topics: Aggression; Anilides; Animals; Cyproterone; Dihydrotestosterone; Female; Flutamide; Lizards; Male; O

1987