Page last updated: 2024-10-27

flutamide and Adenocarcinoma

flutamide has been researched along with Adenocarcinoma in 195 studies

Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"This single institution, randomized, double-blind, placebo controlled study compared flutamide in the dose of 250 mg three times daily (n = 23) versus placebo (n = 23) in patients with histologically proven, previously untreated unresectable pancreatic adenocarcinoma."9.12Flutamide in unresectable pancreatic adenocarcinoma: a randomized, double-blind, placebo-controlled trial. ( Agarwal, A; Chaudhary, A; Negi, SS, 2006)
" We evaluated a combination of finasteride and flutamide as potency-sparing androgen ablative therapy (AAT) for advanced adenocarcinoma of the prostate."9.08Finasteride and flutamide as potency-sparing androgen-ablative therapy for advanced adenocarcinoma of the prostate. ( Berlane, K; Brufsky, A; Fontaine-Rothe, P; Jiroutek, M; Kantoff, P; Kaplan, I; Kaufman, D; Rieker, P, 1997)
" This paper demonstrated that flutamide combined with leuprorelin acetate produced a significant reduction in the growth rate of Dunning R3327-H prostatic adenocarcinoma."7.70[Combination effect of flutamide and leuprorelin acetate on growth of Dunning R3327-H prostatic adenocarcinoma in rats]. ( Abe, F; Kuroiwa, S; Okada, M; Tomura, A, 1998)
"To assess the effectiveness of palladium 103 (Pd-103) brachytherapy in Stage T1 and T2 adenocarcinoma of the prostate."7.70Outpatient ultrasound-guided palladium 103 brachytherapy for localized adenocarcinoma of the prostate: a preliminary report of 434 patients. ( Behar, RJ; Cantor, A; Chovnick, SD; Huff, W; Otheguy, J; Perez, R; Sharkey, J; Solc, Z, 1998)
"To assess the effectiveness of palladium-103 brachytherapy in stage T1 and T2 adenocarcinoma of the prostate."7.70Minimally invasive treatment for localized adenocarcinoma of the prostate: review of 1048 patients treated with ultrasound-guided palladium-103 brachytherapy. ( Behar, RJ; Cantor, A; Chovnick, SD; Donohue, M; Huff, W; Otheguy, J; Perez, R; Rabinowitz, R; Sharkey, J; Solc, Z; Steele, J; Webster, C, 2000)
"Three of 34 patients treated with a TAS regimen incorporating flutamide developed significant hepatic abnormalities: elevated transaminases [2] and fatal hepatic necrosis [1]."7.69Flutamide-induced liver toxicity including fatal hepatic necrosis. ( Chen, A; Crownover, RL; Fu, KK; Holland, J; Krieg, R; Roach, M; Young, BK, 1996)
"We report a primary squamous cell carcinoma of the prostate that developed in a 57-year-old man, 3 years after treatment with leuprolide and flutamide for Stage D1 adenocarcinoma of the prostate."7.69Squamous cell carcinoma of the prostate: a transformation from adenocarcinoma after the use of a luteinizing hormone-releasing hormone agonist and flutamide. ( Braslis, KG; Civantos, F; Davi, RC; Nelson, E; Soloway, MS, 1995)
"The histopathology of 23 radical prostatectomies from patients with prostatic adenocarcinoma pretreated for 3-6 months with combination therapy including a luteinizing hormone-releasing hormone agonist and the antiandrogen drug flutamide was reviewed and compared with the pretreatment biopsies or transurethral resection material."7.68Effect of combination endocrine therapy (LHRH agonist and flutamide) on normal prostate and prostatic adenocarcinoma. A histopathologic and immunohistochemical study. ( Boivin, JC; Dupont, A; Labrie, F; Monfette, G; Pinault, S; Srigley, JR; Têtu, B, 1991)
"A seventy-three year-old patient with prostate cancer underwent radical prostatectomy, followed by total androgen brocking therapy using flutamide and LH-RH agonist."5.30[Fatal hepatic failure following hepatitis caused by flutamide: a case report]. ( Kinebuchi, Y; Murata, Y; Okaneya, T, 1999)
"Men (N=1554) with adenocarcinoma of the prostate (cT2c-T4, N0-Nx) with a prostate-specific antigen (PSA) <150 ng/mL and no evidence of distant metastasis were randomized (June 1992 to April 1995) to short-term ADT (STAD: 4 months of flutamide 250 mg 3 times per day and goserelin 3."5.24Duration of Androgen Deprivation in Locally Advanced Prostate Cancer: Long-Term Update of NRG Oncology RTOG 9202. ( Bedi, M; Brereton, HD; Dignam, JJ; Grignon, DJ; Hanks, GE; Horwitz, EM; Kim, H; Kwok, Y; Lawton, CAF; Lepor, H; Lin, X; Parliament, MB; Pisansky, TM; Rabinovitch, R; Roach, M; Rosenthal, SA; Sandler, HM; Venkatesan, VM; Zeitzer, KL, 2017)
"This single institution, randomized, double-blind, placebo controlled study compared flutamide in the dose of 250 mg three times daily (n = 23) versus placebo (n = 23) in patients with histologically proven, previously untreated unresectable pancreatic adenocarcinoma."5.12Flutamide in unresectable pancreatic adenocarcinoma: a randomized, double-blind, placebo-controlled trial. ( Agarwal, A; Chaudhary, A; Negi, SS, 2006)
"We randomly assigned patients who had never received antiandrogen therapy and who had distant metastases from adenocarcinoma of the prostate to treatment with bilateral orchiectomy and either flutamide or placebo."5.08Bilateral orchiectomy with or without flutamide for metastatic prostate cancer. ( Blumenstein, BA; Bueschen, AJ; Crawford, ED; Culkin, DJ; Eisenberger, MA; Loehrer, PJ; Lowe, BA; McLeod, DG; Miller, G; Sears, K; Thompson, IM; Wilding, G, 1998)
" We evaluated a combination of finasteride and flutamide as potency-sparing androgen ablative therapy (AAT) for advanced adenocarcinoma of the prostate."5.08Finasteride and flutamide as potency-sparing androgen-ablative therapy for advanced adenocarcinoma of the prostate. ( Berlane, K; Brufsky, A; Fontaine-Rothe, P; Jiroutek, M; Kantoff, P; Kaplan, I; Kaufman, D; Rieker, P, 1997)
"In a recent intergroup study under the auspices of the National Cancer Institute, 603 eligible patients with newly diagnosed disseminated adenocarcinoma of the prostate were prospectively randomized in a double-blinded clinical trial to receive either a gonadotropin-releasing hormone analogue (leuprolide) and a nonsteroidal antiandrogen (flutamide) or leuprolide and placebo."5.07The use of flutamide in hormone-refractory metastatic prostate cancer. ( Benson, RC; Blumenstein, BA; Crawford, ED; Eisenberger, MA; McLeod, DG; Spaulding, JT; Spicer, D, 1993)
" We investigated the effects of the proteasome inhibitors MG115 and PSI alone or in combination with different concentrations of the antiandrogen hydroxyflutamide on the cellular proliferation, apoptosis and viability of 10 prostatic adenocarcinoma cell cultures."3.72Proteasome inhibitors and their combination with antiandrogens: effects on apoptosis, cellular proliferation and viability of prostatic adenocarcinoma cell cultures. ( Stöckle, M; Tahmatzopoulos, A; Unteregger, G; Wullich, B; Zwergel, T; Zwergel, U, 2004)
"One hundred and thirty-six patients with adenocarcinoma of prostate were treated with combined androgen block (orchiectomy and flutamide 250 mg, tid)."3.72Anemia in patients on combined androgen block therapy for prostate cancer. ( Cheng, SG; Hua, LX; Li, J; Qian, LX; Sui, YG; Wang, XR; Wu, HF; Zhang, W, 2004)
" Here we report AR gene mutations identified in human prostate cancer and the autochthonous transgenic adenocarcinoma of the mouse prostate model that colocate to residues (668)QPIF(671) at the boundary of the hinge and ligand-binding domain, resulting in receptors that exhibit 2- to 4-fold increased activity compared with wild-type AR in response to dihydrotestosterone, estradiol, progesterone, adrenal androgens, and the AR antagonist, hydroxyflutamide, without an apparent effect on receptor levels, ligand binding kinetics, or DNA binding."3.71Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function. ( Bentel, JM; Buchanan, G; Greenberg, NM; Han, G; Harris, JM; Horsfall, DJ; Marshall, VR; Matusik, RJ; Moore, N; Nahm, HS; Tilley, WD; Yang, M, 2001)
" This paper demonstrated that flutamide combined with leuprorelin acetate produced a significant reduction in the growth rate of Dunning R3327-H prostatic adenocarcinoma."3.70[Combination effect of flutamide and leuprorelin acetate on growth of Dunning R3327-H prostatic adenocarcinoma in rats]. ( Abe, F; Kuroiwa, S; Okada, M; Tomura, A, 1998)
"To assess the effectiveness of palladium 103 (Pd-103) brachytherapy in Stage T1 and T2 adenocarcinoma of the prostate."3.70Outpatient ultrasound-guided palladium 103 brachytherapy for localized adenocarcinoma of the prostate: a preliminary report of 434 patients. ( Behar, RJ; Cantor, A; Chovnick, SD; Huff, W; Otheguy, J; Perez, R; Sharkey, J; Solc, Z, 1998)
"To assess the effectiveness of palladium-103 brachytherapy in stage T1 and T2 adenocarcinoma of the prostate."3.70Minimally invasive treatment for localized adenocarcinoma of the prostate: review of 1048 patients treated with ultrasound-guided palladium-103 brachytherapy. ( Behar, RJ; Cantor, A; Chovnick, SD; Donohue, M; Huff, W; Otheguy, J; Perez, R; Rabinowitz, R; Sharkey, J; Solc, Z; Steele, J; Webster, C, 2000)
" A pilot study was undertaken to test the efficacy of flutamide (an antiandrogen) in the transgenic adenocarcinoma of the mouse prostate (TRAMP) model of prostate cancer."3.70Efficacious chemoprevention of primary prostate cancer by flutamide in an autochthonous transgenic model. ( Greenberg, N; Kuliyev, E; Raghow, S; Steakley, M; Steiner, MS, 2000)
"Patients with bulky clinical Stage C adenocarcinoma of the prostate were given 3 months of hormone treatment consisting of oral Flutamide and monthly Zoladex injections prior to irradiation."3.69The potential for normal tissue dose reduction with neoadjuvant hormonal therapy in conformal treatment planning for stage C prostate cancer. ( Abellera, M; Chen, GT; Chiru, P; Hamilton, RJ; Ray, P; Spelbring, D; Vaida, F; Vijayakumar, S; Yang, FE, 1995)
"To investigate the effect of combination endocrine treatment (CET) or luteinising hormone releasing hormone agonist and flutamide on non-neoplastic prostate, prostatic intraepithelial neoplasia, and prostatic adenocarcinoma."3.69Effects of combination endocrine treatment on normal prostate, prostatic intraepithelial neoplasia, and prostatic adenocarcinoma. ( Fabris, G; Magi-Galluzzi, C; Montironi, R; Muzzonigro, G; Polito, M; Prete, E, 1994)
"Three of 34 patients treated with a TAS regimen incorporating flutamide developed significant hepatic abnormalities: elevated transaminases [2] and fatal hepatic necrosis [1]."3.69Flutamide-induced liver toxicity including fatal hepatic necrosis. ( Chen, A; Crownover, RL; Fu, KK; Holland, J; Krieg, R; Roach, M; Young, BK, 1996)
"We report a primary squamous cell carcinoma of the prostate that developed in a 57-year-old man, 3 years after treatment with leuprolide and flutamide for Stage D1 adenocarcinoma of the prostate."3.69Squamous cell carcinoma of the prostate: a transformation from adenocarcinoma after the use of a luteinizing hormone-releasing hormone agonist and flutamide. ( Braslis, KG; Civantos, F; Davi, RC; Nelson, E; Soloway, MS, 1995)
"The histopathology of 23 radical prostatectomies from patients with prostatic adenocarcinoma pretreated for 3-6 months with combination therapy including a luteinizing hormone-releasing hormone agonist and the antiandrogen drug flutamide was reviewed and compared with the pretreatment biopsies or transurethral resection material."3.68Effect of combination endocrine therapy (LHRH agonist and flutamide) on normal prostate and prostatic adenocarcinoma. A histopathologic and immunohistochemical study. ( Boivin, JC; Dupont, A; Labrie, F; Monfette, G; Pinault, S; Srigley, JR; Têtu, B, 1991)
"Twenty-one patients with advanced prostatic adenocarcinoma previously untreated with conventional endocrine therapy were treated with an oral non-steroidal antiandrogen, flutamide."3.66Experience with flutamide in previously untreated patients with advanced prostatic cancer. ( Sogani, PC; Whitmore, WF, 1979)
"The treatment for prostate cancer patients with biochemical failure after local therapy remains controversial."2.77Efficacy of peripheral androgen blockade in prostate cancer patients with biochemical failure after definitive local therapy: results of Cancer and Leukemia Group B (CALGB) 9782. ( Ahles, T; Gu, L; Halabi, S; Hussain, A; Kaplan, E; Kelly, WK; Monk, JP; Philips, G; Picus, J; Small, EJ; Vogelzang, N, 2012)
"Flutamide (750 g/d) was administered for 1 mo."2.77Addition of radiotherapy to long-term androgen deprivation in locally advanced prostate cancer: an open randomised phase 3 trial. ( Mazeron, JJ; Molinie, V; Mottet, N; Peneau, M; Richaud, P, 2012)
"To study whether use of neoadjuvant androgen deprivation therapy (N-ADT) combined with whole pelvic radiotherapy (WPRT) for high-risk prostate cancer patients was associated with survival benefit over prostate radiotherapy (PORT) only."2.74Benefit of whole pelvic radiotherapy combined with neoadjuvant androgen deprivation for the high-risk prostate cancer. ( Antczak, A; Baczyk, M; Kwias, Z; Martenka, P; Milecki, P; Skowronek, J, 2009)
"Men with localized but unfavorable-risk prostate cancer who were treated with RT and 6 months of planned combined AST appear to have an increased risk of recurrence when treated with less than as compared with 6 months of the antiandrogen."2.73Risk of prostate cancer recurrence in men treated with radiation alone or in conjunction with combined or less than combined androgen suppression therapy. ( Chen, MH; D'Amico, AV; Kantoff, PW; Loffredo, B; Renshaw, AA, 2008)
"Among men with androgen independent prostate cancer, no clear association could be detected between body mass index and progression-free survival, overall survival or prostate specific antigen response."2.73Association of body mass index with response and survival in men with metastatic prostate cancer: Southwest Oncology Group trials 8894 and 9916. ( Crawford, ED; Goldman, B; Hussain, M; Klein, EA; Montgomery, RB; Page, S; Petrylak, DP; Tangen, CM, 2007)
"818 men with locally advanced prostate cancer were randomly assigned to: no androgen deprivation (ie, radiotherapy alone: 66 Gy in 33 fractions of 2 Gy per day over 6."2.71Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial. ( Atkinson, C; Christie, D; D'Este, C; Denham, JW; Duchesne, G; Franklin, I; Joseph, D; Kovacev, O; Lamb, DS; Mameghan, H; Matthews, J; North, J; Poulsen, M; Spry, NA; Steigler, A; Tai, KH; Turner, S; Wynne, C, 2005)
"Pretreatment with flutamide increased the serum testosterone level, but the testosterone surge after leuprorelin administration was almost the same in all 5 treatment groups."2.70Optimal starting time for flutamide to prevent disease flare in prostate cancer patients treated with a gonadotropin-releasing hormone agonist. ( Kumon, H; Maki, Y; Nasu, Y; Noda, M; Saika, T; Suyama, B; Tsushima, T; Yamato, T, 2001)
"The primary clinical events were disease progression and survival."2.69Exploratory analysis on the effect of race on clinical outcome in patients with advanced prostate cancer receiving bicalutamide or flutamide, each in combination with LHRH analogues. The Casodex Combination Study Group. ( Block, NL; Kelley, RP; Kolvenbag, GJ; McLeod, DG; Patterson, AL; Sarosdy, MF; Schellhammer, PF; Sharifi, R; Soloway, MS; Venner, PM; Vogelzang, NJ, 1999)
"To evaluate the efficacy of chemoendocrine therapy for the initial treatment of stage D2 prostate cancer, we conducted a prospective randomized study which compared combined androgen blockade alone to that combined with UFT."2.69[Primary treatment for stage D2 prostate cancer: a randomized study of combined androgen blockade alone versus combined with UFT]. ( Akazawa, S; Aki, M; Hashine, K; Kuwahara, M; Sumiyoshi, Y; Takenaka, A; Yamamoto, A, 1999)
"Flutamide is a potent antiandrogen widely used in clinical practice for patients with metastatic prostate cancer."2.68Phase II study of flutamide as second line chemotherapy in patients with advanced pancreatic cancer. ( Hilsenbeck, SG; Razvillas, B; Rothenberg, ML; Sharma, A; Sharma, JJ; Stephens, CD, 1997)
"To compare the efficacy and safety of bicalutamide and flutamide, each used in combination with luteinizing hormone-releasing analogue (LHRH-A) therapy, in patients with untreated metastatic (Stage D2) prostate cancer."2.68A controlled trial of bicalutamide versus flutamide, each in combination with luteinizing hormone-releasing hormone analogue therapy, in patients with advanced prostate cancer. Casodex Combination Study Group. ( Block, N; Jones, J; Kolvenbag, G; Patterson, AL; Sarosdy, M; Schellhammer, P; Sharifi, R; Soloway, M; Venner, P; Vogelzang, N, 1995)
"A randomized, multicenter trial, double-blind for antiandrogen therapy, compared the antiandrogens bicalutamide and flutamide, each combined with luteinizing hormone-releasing hormone analogue therapy (LHRH-A) in 813 patients with Stage D2 prostate carcinoma."2.68A controlled trial of bicalutamide versus flutamide, each in combination with luteinizing hormone-releasing hormone analogue therapy, in patients with advanced prostate carcinoma. Analysis of time to progression. CASODEX Combination Study Group. ( Block, NL; Chen, Y; Kolvenbag, GJ; Patterson, AL; Sarosdy, MF; Schellhammer, PF; Sharifi, R; Soloway, MS; Venner, PM; Vogelzang, NJ, 1996)
"flutamide 3 times daily was evaluated prospectively before cessation of the flutamide."2.68Characterization of patients with androgen-independent prostatic carcinoma whose serum prostate specific antigen decreased following flutamide withdrawal. ( Dieringer, P; Herrada, J; Logothetis, CJ, 1996)
"Although the only opportunity to cure prostate cancer is treatment at an early stage, radical prostatectomy has remained relatively unpopular because 40-50% of prostate cancers estimated at diagnosis as confined to the prostate are found to be at a more advanced stage following histopathological analysis of the surgical specimen."2.67Downstaging of localized prostate cancer by neoadjuvant therapy with flutamide and lupron: the first controlled and randomized trial. ( Cusan, L; Diamond, P; Dupont, A; Fradet, Y; Gomez, J; Koutsilieris, M; Labrie, F; Lemay, M; Suburu, R; Têtu, B, 1993)
"All estramustine-treated patients lost their libido, whereas only 20 per cent of the patients treated with flutamide did so."2.66Clinical evaluation of flutamide and estramustine as initial treatment of metastatic carcinoma of prostate. ( Andersson, SO; Beckman, KW; Johansson, JE; Lingårdh, G; Zador, G, 1987)
"Flutamide appears to be a safe antiandrogen, usually effective in the management of patients with advanced prostatic cancer who have had no prior endocrine therapy."2.65Experience with flutamide in patients with advanced prostatic cancer without prior endocrine therapy. ( Sogani, PC; Vagaiwala, MR; Whitmore, WF, 1984)
" This technique has been used most commonly to treat prostate cancers in combination with hormonal therapy."2.42Rotational 3D-conformal radiation therapy (conformation therapy) combined with hormone therapy for the treatment of stage B2/C prostate cancer in Japanese men. ( Igaki, H; Kaizu, T; Karasawa, K; Matsuda, T; Niibe, Y; Shinohara, M; Tanaka, Y, 2003)
"Unfortunately, every treatment for prostate cancer has adverse effects with negative impact in health-related quality of life."2.42Monotherapy in advanced prostate cancer: an overview. ( Baltogiannis, D; Charalabopoulos, K; Giannakopoulos, X; Sofikitis, N, 2004)
"Ten cases of SIADH caused by prostatic cancer have been reported including the present case."2.41Adenocarcinoma of the prostate with ectopic antidiuretic hormone production: a case report. ( Abe, H; Ito, H; Miura, T; Nishimura, T; Oaki, Y; Oka, F; Uchikoba, T, 2000)
"Under the diagnosis of prostatic cancer with multiple pulmonary metastasis, we performed total androgen blockade (TAB) consisting of luteinizing hormone releasing hormone agonist and flutamide following dietylstilbestrol (DES) intravenous injection therapy."2.41[Prostatic cancer with multiple pulmonary metastases treated successfully with hormonal therapy: a case report]. ( Fukuda, M; Fuse, H; Hirano, S; Takashima, H, 2002)
"We report a case of prostatic cancer in a 73-year-old man detected by abnormalities in chest X-ray and serum prostate specific antigen (PSA) level."2.41[Successful complete androgen blockade (CAB) therapy for prostatic cancer detected from multiple lung metastases: a case report]. ( Hashimoto, H; Inada, F; Ishida, H; Kawakami, N; Kitahara, K; Masui, N; Saga, Y; Tokumitsu, M; Yachiku, S, 2001)
"Up-regulated PCDH1 promotes pancreatic cancer cell metastasis."1.91PCDH1, a poor prognostic biomarker and potential target for pancreatic adenocarcinoma metastatic therapy. ( Chen, Y; Du, X; He, X; Ren, X; Tai, Y; Yi, X; Zou, X, 2023)
" The use of HIFU in combination with androgen deprivation was associated with a decrease in numerical density of microvessels in zones of tumor and non-tumor parenchyma in patients with relapses."1.48Status of the Microcirculatory Network as a Factor of Prognosis and Evaluation of Therapeutic Efficiency in Prostate Cancer Treated by High-Intensity Focused Ultrasound in Combination with Androgen Deprivation. ( Abdullaev, NA; Bakarev, MA; Kachesov, IV; Levin, VP; Neimark, AI, 2018)
"Treatment choices for metastatic prostate cancer are complex and can involve men balancing survival versus quality of life."1.35Eliciting patient preferences for hormonal therapy options in the treatment of metastatic prostate cancer. ( Dewilde, S; Kleinman, L; Lloyd, A; Penson, D, 2008)
"The present data suggest that those prostate cancer patients who have even marginally elevated adrenal androgens may especially benefit from combined androgen blockade."1.35Partial androgen suppression consequent to increased secretion of adrenal androgens in a patient with prostate cancer treated with long-acting GnRH agonists. ( Belanger, A; Chertin, B; Farkas, A; Fridmans, A; Hartman, H; Labrie, F; Spitz, IM, 2009)
"More than 85% of men with prostate cancer die of other causes."1.34Prostate-cancer-specific survival and clinical progression-free survival in men with prostate cancer treated intermittently with testosterone-inactivating pharmaceuticals. ( Jennrich, R; Johnson, H; Lam, R; Scholz, M; Strum, S; Trilling, T, 2007)
"We report the case of a patient with prostate cancer who develops mediastinal lymphadenopathy, pulmonary nodules and cutaneous metastases 8 years after the diagnosis."1.34[Mediastinal lymph nodes during the course of a metastatic prostate cancer]. ( Aguilera Tubet, C; Ballestero Diego, R; Roca Edreira, A; Villanueva Peña, A; Zubillaga Guerrero, S, 2007)
"The incidence and discovery rate of prostate cancer is increased in recent years; with advanced age and multiple organs dysfunction, the advanced prostate cancer patients have poor quality of life."1.33[Experience in treating advanced prostate cancer with bladder outlet obstruction]. ( Chen, JH; Kong, L; Sheng, XJ; Ye, M; Zhang, L; Zhu, YJ, 2005)
"We herein report the clinical outcome of radical radiation therapy combined with neoadjuvant hormonal therapy (NHT) for stage III (International Union Against Cancer [UICC] 1997: UICC 97) prostate cancer."1.33Results of radiation therapy combined with neoadjuvant hormonal therapy for stage III prostate cancer: comparison of two different definitions of PSA failure. ( Hiraoka, M; Kamoto, T; Kinoshita, H; Mitsumori, M; Mizowaki, T; Nagata, Y; Negoro, Y; Ogawa, O; Sasai, K; Sasaki, Y; Takayama, K, 2006)
"A 88-year-old man with prostate cancer was receiving non-steroidal anti-androgen therapy (flutamide, 375 mg/day)."1.32Interstitial pneumonitis related to flutamide monotherapy for prostate cancer. ( Fujimoto, N; Matsumoto, T; Nomura, M; Sato, H, 2004)
"During the diagnostic work-up, prostate cancer was diagnosed."1.32Cholestatic jaundice as a paraneoplastic manifestation of prostate adenocarcinoma. ( Grigoriadis, N; Kallinikidis, T; Kalpidis, P; Karakolios, A; Kasapis, C, 2003)
"Once metastatic, prostate cancer was regarded as a systemic disease that is not amenable to surgical therapy."1.32Biochemical remission after resection of prostate cancer lung metastasis. ( Brooks, JD; Chao, DH; Higgins, JP, 2004)
"Four patients suffered bone fractures, none pathological."1.31A pilot study of intermittent androgen ablation in advanced prostate cancer in Japanese men. ( Baba, S; Egawa, S; Kuwao, S; Matsumoto, K; Mizoguchi, H; Takashima, R, 2000)
"Twenty selected patients with prostate cancer, who were treated with hormonal therapy and demonstrated biochemical downstaging by reduction of PSA prior to RP and bilateral pelvic node dissection at the Tohsei National Hospital between January 1997 and August 2001, are reported on."1.31Neoadjuvant hormonal therapy prior to radical prostatectomy: evaluation of pathological downstaging and biochemical relapse. ( Kiriyama, I; Nishimura, T; Ogaki, K; Ohba, S, 2002)
"In hemodialysis patients, few cases of prostate cancer have been reported until recently."1.31Prostate cancer with multiple lung metastases in a hemodialysis patient. ( Aoyagi, T; Hata, M; Hayakawa, K; Matsumoto, M; Miyaji, K, 2000)
"Eighteen patients with prostate cancer and 17 healthy subjects matched for age and body mass index were included."1.31Hormonal regulation of appetite and body mass in patients with advanced prostate cancer treated with combined androgen blockade. ( Bryc, W; Kokot, F; Nowicki, M, 2001)
"The flutamide therapy was immediately discontinued and this resulted in spontaneous remission (clinical and liver function test results returned to normal) during the next 8 weeks."1.31Flutamide-induced acute hepatitis in advanced prostate cancer patients. ( Kraus, I; Oguic, R; Vitezic, D, 2001)
"Apoptosis in prostate cancer was evaluated after three months of combined endocrine therapy to investigate the association with tumour grade, tumour stage, and the immunohistochemical detection of p53 and bcl-2 in tumour cells before and after therapy."1.30Detection of apoptosis by the TUNEL technique in clinically localised prostatic cancer before and after combined endocrine therapy. ( Colecchia, M; Colloi, D; Del Boca, C; Frigo, B; Guardamagna, A; Leopardi, O; Zucchi, A, 1997)
"Suramin has demonstrated modest activity against prostate cancer and is being investigated in clinical trials."1.30Acute renal failure in a patient receiving treatment with suramin. ( Harbour, D; Liebmann, J; Smith, A, 1997)
"Their density in prostatic cancer increases following hormonal therapy and varies in relation to the tumoral degree or histological evaluation, suggesting a role of neuroendocrine cells in human prostatic cancer."1.30Neuroendocrine cells in benign prostatic hyperplasia and prostatic carcinoma: effect of hormonal treatment. ( del Valle, M; Escaf, S; Guate, JL; Menendez, CL; Vega, JA, 1997)
"A seventy-three year-old patient with prostate cancer underwent radical prostatectomy, followed by total androgen brocking therapy using flutamide and LH-RH agonist."1.30[Fatal hepatic failure following hepatitis caused by flutamide: a case report]. ( Kinebuchi, Y; Murata, Y; Okaneya, T, 1999)
"A given prostate cancer patient's response to therapy may be predicted by following apoptotic and mitotic activity, as well as Ki-67 and p53 expression in repeated biopsies."1.30Apoptosis, mitosis, p53, bcl(2), Ki-67 and clinical outcome in prostate carcinoma treated by androgen ablation. ( Bély, M; Lovász, S; Romics, I; Szegedi, Z; Szende, B; Torda, I, 1999)
"To compare disease progression and survival of patients with stage D1 adenocarcinoma after treatment with either early androgen ablation alone or combined with radical prostatectomy."1.30Early endocrine therapy versus radical prostatectomy combined with early endocrine therapy for stage D1 prostate cancer. ( Lubos, W; Schmeller, N, 1997)
"Turosteride (FCE 26073) is a new, potent, and selective 5 alpha-reductase inhibitor."1.30Effect of turosteride, a 5 alpha-reductase inhibitor, on the Dunning R3327 rat prostatic carcinoma. ( di Salle, E; Giudici, D; Zaccheo, T, 1997)
"Accordingly, the final diagnosis was prostate cancer (cT3N4M1, stage D2)."1.30[Serum concentrations of flutamide and goserelin in a prostate cancer patient with obstructive nephropathy: a case report]. ( Higashi, T; Maruyama, Y; Nagayoshi, J, 1999)
"Patients with node-positive prostate cancer that is regionally localized (T1-4, N1-3, M0) have a relatively poor prognosis when a single-treatment modality such as radical surgery, definitive radiotherapy, or androgen ablation is used."1.29Influence of radiotherapy on node-positive prostate cancer treated with androgen ablation. ( Pollack, A; Sands, ME; Zagars, GK, 1995)
"Secondary testicular tumors are very rare."1.29[Bilateral testicular metastasis of an adenocarcinoma of the prostate]. ( Agnanti, N; Bai, M; Giannakopoulos, X; Grammeniatis, E; Stefanou, D, 1994)
"We describe a florid xanthomatous histiocytic reaction in the pelvic lymph nodes of a patient treated with androgen deprivation therapy prior to radical prostatectomy."1.29Florid xanthomatous pelvic lymph node reaction to metastatic prostatic adenocarcinoma. A sequela of preoperative androgen deprivation therapy. ( Gormley, EA; Schned, AR, 1996)
"Flutamide is a nonsteroidal antiandrogen commonly used in the treatment of prostate cancer."1.29Flutamide-induced toxic hepatitis. Potential utility of ursodeoxycholic acid administration in toxic hepatitis. ( Barbara, L; Cicognani, C; Malavolti, M; Morselli-Labate, AM; Sama, C, 1996)
"Metastases to the meninges from prostatic cancer are rare, accounting for less than 0."1.29Hormonal ablation as effective therapy for carcinomatous meningitis from prostatic carcinoma. ( DeAngelis, LM; Mencel, PJ; Motzer, RJ, 1994)
"A 75-year-old patient presented with a superior vena cava syndrome (SVCS) lasting 3 years."1.29Metastatic carcinoma of the prostate presenting as a superior vena cava syndrome. ( Bellas, C; Hernanz, I; Molina, JP; Montalbán, C; Moreno, MA, 1993)
"in 1941, hormonal treatment of advanced prostatic cancer has been directed primarily at neutralizing testicular androgens by orchiectomy or estrogen therapy."1.27[Combined anti-androgen treatment in adenocarcinoma of the prostate: first use of a new therapeutically efficacious principle in hormone-dependent cancer]. ( Bélanger, A; Dupont, A; Labrie, F; Lacourcière, Y; Monfette, G; Monfette, JE, 1986)
"Patients (154) with clinical stage D2 prostate cancer with no previous endocrine therapy or chemotherapy received the combination therapy with the pure antiandrogen Flutamide and the LHRH agonist [D-Trp6]LHRH ethylamide for an average of 22 months (3-49 months)."1.27Combination therapy with flutamide and castration (orchiectomy or LHRH agonist): the minimal endocrine therapy in both untreated and previously treated patients. ( Belanger, A; Borsanyi, JP; Dupont, A; Emond, J; Giguere, M; Labrie, F; Lachance, R; Lacourciere, Y; Monfette, G, 1987)
"Three patients have died from prostate cancer while three have died from other causes, 93."1.27Combination therapy with flutamide and [D-Trp6]LHRH ethylamide for stage C prostatic carcinoma. ( Belanger, A; Bergeron, N; Borsanyi, JP; Cusan, L; Dupont, A; Emond, J; Giguere, M; Labrie, F; Lacourciere, Y, 1988)
"Ten men with prostatic cancer, stage T3M0 Nx or more, who were anxious to maintain sexual potency, were treated with flutamide."1.27Flutamide--an antiandrogen inhibiting prostatic cancer and prostatic secretion with retention of potency. ( Johansson, JE; Schnürer, LB; Stegmayr, B, 1988)

Research

Studies (195)

TimeframeStudies, this research(%)All Research%
pre-199019 (9.74)18.7374
1990's87 (44.62)18.2507
2000's74 (37.95)29.6817
2010's13 (6.67)24.3611
2020's2 (1.03)2.80

Authors

AuthorsStudies
Du, X1
Yi, X1
Zou, X1
Chen, Y2
Tai, Y1
Ren, X1
He, X1
Fukuoka, K1
Teishima, J1
Nagamatsu, H1
Inoue, S1
Hayashi, T1
Mita, K1
Shigeta, M1
Kobayashi, K1
Kajiwara, M1
Kadonishi, Y1
Tacho, T1
Matsubara, A1
Lawton, CAF2
Lin, X1
Hanks, GE1
Lepor, H1
Grignon, DJ2
Brereton, HD1
Bedi, M1
Rosenthal, SA1
Zeitzer, KL3
Venkatesan, VM1
Horwitz, EM2
Pisansky, TM2
Kim, H1
Parliament, MB1
Rabinovitch, R2
Roach, M3
Kwok, Y2
Dignam, JJ1
Sandler, HM2
Bakarev, MA1
Levin, VP1
Kachesov, IV1
Abdullaev, NA1
Neimark, AI1
Moughan, J1
Dicker, AP1
Gore, EM2
Seider, MJ1
Hsu, IC1
Hartford, AC1
Yamoah, K1
Jones, CU2
Michalski, JM1
Lee, WR1
Rotman, M2
Pryzant, RM1
Kim, HE1
Thomas, CR1
Shipley, WU3
Zapatero, A1
Guerrero, A1
Maldonado, X1
Alvarez, A1
Gonzalez San Segundo, C1
Cabeza Rodríguez, MA1
Macias, V1
Pedro Olive, A1
Casas, F1
Boladeras, A1
de Vidales, CM1
Vazquez de la Torre, ML1
Villà, S1
Perez de la Haza, A1
Calvo, FA1
Krauss, DJ1
Hu, C1
Bahary, JP1
Souhami, L1
Chafe, SM1
Leibenhaut, MH1
Narayan, S1
Torres-Roca, J1
Michalski, J1
Donavanik, V1
Sandler, H1
McGowan, DG1
D'Amico, AV4
Chen, MH2
Renshaw, AA4
Loffredo, B1
Kantoff, PW5
Spitz, IM1
Chertin, B1
Fridmans, A1
Farkas, A1
Belanger, A9
Hartman, H1
Labrie, F17
Alexander, A1
Crook, J1
Jones, S1
Malone, S1
Bowen, J1
Truong, P1
Pai, H1
Ludgate, C1
Milecki, P1
Baczyk, M1
Skowronek, J1
Antczak, A1
Kwias, Z1
Martenka, P1
Narimoto, K1
Mizokami, A1
Izumi, K1
Mihara, S1
Sawada, K1
Sugata, T1
Shimamura, M1
Miyazaki, K1
Nishino, A1
Namiki, M1
Armstrong, JG1
Gillham, CM1
Dunne, MT1
Fitzpatrick, DA1
Finn, MA1
Cannon, ME1
Taylor, JC1
O'Shea, CM1
Buckney, SJ1
Thirion, PG1
Pérez-Montaña, A1
Navarro, JT1
Juncà, J1
Ribera, JM1
Monk, JP1
Halabi, S2
Picus, J1
Hussain, A1
Philips, G1
Kaplan, E1
Ahles, T1
Gu, L1
Vogelzang, N2
Kelly, WK1
Small, EJ2
Mottet, N1
Peneau, M1
Mazeron, JJ2
Molinie, V1
Richaud, P1
Piccionello, AP1
Pitarresi, G1
Pace, A1
Triolo, D1
Picone, P1
Buscemi, S1
Giammona, G1
Bolla, M1
Fukuda, M1
Takashima, H1
Fuse, H1
Hirano, S1
Kiriyama, I1
Ogaki, K1
Ohba, S1
Nishimura, T2
Glass, TR1
Tangen, CM4
Crawford, ED8
Thompson, I1
Miller, NL1
Bissonette, EA1
Bahnson, R1
Wilson, J1
Theodorescu, D1
Preston, DM1
Torréns, JI1
Harding, P1
Howard, RS1
Duncan, WE1
McLeod, DG5
Kaur, C1
Thami, GP1
Sciarra, A1
Monti, S1
Gentile, V1
Mariotti, G1
Cardi, A1
Voria, G1
Lucera, R1
Di Silverio, F1
Karasawa, K1
Kaizu, T1
Niibe, Y1
Igaki, H1
Shinohara, M1
Tanaka, Y1
Matsuda, T1
Kosugi, M1
Hanawa, Y1
Momma, T1
Saito, S1
Hirose, S1
Oh, WK1
Manola, J2
Bittmann, L1
Brufsky, A2
Kaplan, ID1
Smith, MR1
Kaufman, DS1
Jani, AB1
Basu, A1
Abdalla, I1
Connell, PP1
Krauz, L1
Vijayakumar, S2
Sheski, FD1
Henley, JD1
Foster, RS1
Einhorn, LH1
Barqawi, AB1
Moul, JW1
Ziada, A1
Handel, L1
Karakolios, A1
Kasapis, C1
Kallinikidis, T1
Kalpidis, P1
Grigoriadis, N1
Chao, DH1
Higgins, JP1
Brooks, JD1
Faulkner, JR1
Thompson, IM3
Hirano, D1
Eisenberger, M1
Hussain, M2
de Leval, J1
Boca, P1
Yousef, E1
Nicolas, H1
Jeukenne, M1
Seidel, L1
Bouffioux, C1
Coppens, L1
Bonnet, P1
Andrianne, R1
Wlatregny, D1
Zwergel, T1
Tahmatzopoulos, A1
Wullich, B1
Zwergel, U1
Stöckle, M2
Unteregger, G1
Sato, N1
Akakura, K1
Isaka, S1
Nakatsu, H1
Tanaka, M1
Ito, H2
Masai, M1
Loffredo, M3
DellaCroce, A1
Nomura, M1
Sato, H1
Fujimoto, N1
Matsumoto, T1
Baltogiannis, D1
Giannakopoulos, X2
Charalabopoulos, K1
Sofikitis, N1
Qian, LX1
Hua, LX1
Wu, HF1
Sui, YG1
Cheng, SG1
Zhang, W1
Li, J1
Wang, XR1
Negi, SS1
Agarwal, A1
Chaudhary, A1
Sheng, XJ1
Zhu, YJ1
Ye, M1
Chen, JH1
Zhang, L1
Kong, L1
Denham, JW1
Steigler, A1
Lamb, DS1
Joseph, D1
Mameghan, H1
Turner, S1
Matthews, J1
Franklin, I1
Atkinson, C1
North, J1
Poulsen, M1
Christie, D1
Spry, NA1
Tai, KH1
Wynne, C1
Duchesne, G1
Kovacev, O1
D'Este, C1
Papaioannides, D1
Korantzopoulos, P1
Bouropoulos, C1
Latsi, P1
Fotinou, M1
Orphanidou, D1
Konski, A1
Watkins-Bruner, D1
Brereton, H1
Feigenberg, S1
Hanks, G2
Yamamoto, S1
Yonese, J1
Kawakami, S1
Tsukamoto, T1
Ohkubo, Y1
Tatokoro, M1
Fukui, I1
Mitsumori, M1
Sasaki, Y1
Mizowaki, T1
Takayama, K1
Nagata, Y1
Hiraoka, M1
Negoro, Y1
Sasai, K1
Kinoshita, H1
Kamoto, T1
Ogawa, O1
Metzner, C1
Nöldge, G1
Delling, G1
Oehler, U1
Nawroth, P1
Kasperk, C1
Klokk, TI1
Kurys, P1
Elbi, C1
Nagaich, AK1
Hendarwanto, A1
Slagsvold, T1
Chang, CY1
Hager, GL1
Saatcioglu, F1
Heymann, JJ1
Benson, MC1
O'Toole, KM1
Malyszko, B1
Brody, R1
Vecchio, D1
Schiff, PB1
Mansukhani, MM1
Ennis, RD1
Mercader, M1
Sengupta, S1
Bodner, BK1
Manecke, RG1
Cosar, EF1
Moser, MT1
Ballman, KV1
Wojcik, EM1
Kwon, ED1
Cho, YM1
Takahashi, S1
Asamoto, M1
Suzuki, S1
Tang, M1
Shirai, T1
Lloyd, A1
Penson, D1
Dewilde, S1
Kleinman, L1
Slovin, SF1
Miquel, M1
Soler, A1
Vaqué, A1
Ojanguren, I1
Costa, J1
Planas, R1
Montgomery, RB1
Goldman, B1
Petrylak, DP1
Page, S1
Klein, EA1
Lawton, CA3
Bae, K1
Pilepich, M1
Shipley, W1
Roca Edreira, A1
Aguilera Tubet, C1
Villanueva Peña, A1
Ballestero Diego, R1
Zubillaga Guerrero, S1
Scholz, M1
Lam, R1
Strum, S1
Jennrich, R1
Johnson, H1
Trilling, T1
Vollmer, R1
McMahon, E1
Sanford, B1
Archer, L1
Vogelzang, NJ3
Sartor, AO1
Hussain, MH1
Eisenberger, MA3
Parab, M1
Fontana, JA1
Chapman, RA1
Mills, GM1
Raghavan, D1
Tutton, PJ1
Barkla, DH1
Sogani, PC3
Vagaiwala, MR1
Whitmore, WF3
Soloway, MS5
Ahmed, T1
Benedetto, P1
Yagoda, A1
Watson, RC1
Scher, HI1
Herr, HW1
Pertschuk, L1
Isaacs, JT1
Weissman, RM1
Coffey, DS1
Scott, WW1
Yang, FE1
Chen, GT1
Ray, P1
Vaida, F1
Chiru, P1
Hamilton, RJ1
Spelbring, D1
Abellera, M1
Keizur, JJ1
Kane, CJ1
North, R1
Leidich, RB1
Rozanski, TA1
Faerber, GJ1
Johnson, TL1
Cusan, L10
Gomez, JL4
Dupont, A15
Diamond, P4
Lemay, M4
Moore, S1
Andros, EA1
Danesghari, F1
Schulman, CC1
Sassine, AM1
Armas, OA1
Aprikian, AG1
Melamed, J1
Cordon-Cardo, C1
Cohen, DW1
Erlandson, R1
Fair, WR3
Reuter, VE1
Montironi, R3
Magi-Galluzzi, C1
Muzzonigro, G3
Prete, E1
Polito, M3
Fabris, G1
Van de Voorde, WM1
Elgamal, AA1
Van Poppel, HP1
Verbeken, EK1
Baert, LV1
Lauweryns, JM1
Sands, ME1
Pollack, A1
Zagars, GK1
Cheson, BD1
Kaplan, RS1
Phillips, PH1
Brenner, PC1
Rettig, WJ1
Sanz-Moncasi, MP1
Reuter, V1
Aprikian, A1
Old, LJ1
Garin-Chesa, P1
Schellhammer, P1
Sharifi, R3
Block, N1
Soloway, M1
Venner, P1
Patterson, AL3
Sarosdy, M1
Jones, J1
Kolvenbag, G1
Cher, ML1
Shinohara, K1
Breslin, S1
Vapnek, J1
Carroll, PR2
Whittington, R1
Malkowicz, B1
Barnes, MM1
Broderick, GA1
Van Arsdalen, K1
Dougherty, MJ1
Wein, AJ1
Dran, G1
Luthy, IA2
Molinolo, AA2
Montecchia, F1
Charreau, EH1
Pasqualini, CD1
Lanari, C2
Koutsilieris, M2
Pilepich, MV3
Krall, JM1
al-Sarraf, M1
John, MJ2
Doggett, RL1
Sause, WT1
Abrams, RA2
Rubin, P2
Bai, M1
Grammeniatis, E1
Stefanou, D1
Agnanti, N1
Braslis, KG1
Davi, RC1
Nelson, E1
Civantos, F2
Magi Galluzzi, C1
Giannulis, I1
Diamanti, L1
Scarpelli, M1
Morote, J1
Lorente, JA1
Vallejo, C1
Narayan, P1
Lowe, BA2
Gomez, J3
Suburu, R3
Fradet, Y3
Têtu, B5
Ferguson, J1
Zincke, H1
Ellison, E1
Bergstrahl, E1
Bostwick, DG1
Mencel, PJ1
DeAngelis, LM1
Motzer, RJ1
Carrascosa, M1
Perez-Castrillon, JL1
Mendez, MA1
Cillero, L1
Valle, R1
Benson, RC1
Blumenstein, BA2
Spicer, D1
Spaulding, JT1
Berrevoets, CA1
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Mulder, E1
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Frissora-Rodeo, C1
Marshall, AT1
Reiter, BP1
Paronetto, F1
Montalbán, C1
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Molina, JP1
Hernanz, I1
Bellas, C1
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Mottrie, AM1
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Mappes, C1
Störkel, S1
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Schned, AR1
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Crownover, RL1
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Krieg, R1
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Ruiz Alvarez Cienfuegos, F1
Leva Vallejo, M1
Requena Tapia, MJ1
Merchan García, JA1
Prieto Castro, R1
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Hammond, EH1
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Muller, MJ1
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di Salle, E1
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Gómez Ruiz, JJ1
López López, AF1
Romero Maroto, YJ1
Patel, H1
Rhee, E1
Zimmern, PE1
Fernández Peña, CM1
Morano Amado, LE1
Montes Santiago, J1
Fachal, C1
Candas, B1
Kagebayashi, Y1
Ozono, S2
Takashima, K1
Yoshikawa, M2
Hayashi, Y1
Kaneko, Y1
Maruyama, Y3
Hirao, Y2
Okajima, E2
Figg, WD1
Kroog, G1
Duray, P1
Walther, MM1
Patronas, N1
Sartor, O1
Reed, E1
Pantel, K1
Enzmann, T1
Köllermann, J1
Caprano, J1
Riethmüller, G1
Köllermann, MW1
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Bogdanowicz, JF1
Seldenrijk, CA1
Mulder, PG1
Fontaine-Rothe, P1
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Colecchia, M1
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Mortini, P1
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Díaz Bermúdez, J1
Duarte Novo, J1
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Chantada Abal, V1
Sánchez Rodríguez, J1
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del Valle, M1
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Unger, PD1
Wang, Q1
Gordon, RE1
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Stone, N1
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Jennings, TA1
Ross, JS1
Nazeer, T1
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Kuroiwa, S1
Okada, M1
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Sharma, JJ1
Razvillas, B1
Stephens, CD1
Hilsenbeck, SG1
Sharma, A1
Rothenberg, ML1
Reid, MB1
Glode, LM1
Sharkey, J2
Chovnick, SD2
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Perez, R2
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Solc, Z2
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Cantor, A2
Miller, G1
Loehrer, PJ1
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Culkin, DJ1
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Montecchia, MF1
Lamb, C1
Pazos, P1
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Vanzulli, S1
Matsushima, H1
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Kawabe, K1
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Murata, Y1
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Kelley, RP1
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Hashine, K1
Kuwahara, M1
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Zungri Telo, E1
de la Fuente Buceta, A1
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Kurita, M1
Kato, Y1
Tamura, Y1
Suzuki, K1
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Takashima, R1
Matsumoto, K1
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Kuwao, S1
Baba, S1
Rabinowitz, R1
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Webster, C1
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Raghow, S1
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Steiner, MS1
Granter, SR1
del Vecchio, MT1
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Uchikoba, T1
Oaki, Y1
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Martínez Moreno, J1
Martín Arribas, MI1
Pérez Villoria, A1
De la Serna Higuera, C1
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Cecchi, M1
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Marshall, VR1
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Tokumitsu, M1
Inada, F1
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Kawakami, N1
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Ishida, H2
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Hashimoto, H1
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Tucker, SJ1
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Suyama, B1
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Lawton, C1
Machtay, M1
Grignon, D1
Kraus, I1
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Oguic, R1
Sprangers, MA1
Moinpour, CM1
Moynihan, TJ1
Patrick, DL1
Revicki, DA1
Jorion, JL1
Tremblay, M1
Kaskas, M1
Sauvage, L1
Hattab, B1
Zaragoza, MR1
Grossman, HB1
Pinault, S2
Gagnon, J1
Monfette, G7
Dawson, NA1
Weiss, RB1
Linehan, WM1
Frank, JA1
Jacob, JL1
Gelmann, EP1
Srigley, JR1
Boivin, JC1
Emond, J5
Manhès, G1
Bergeron, N2
Lacourcière, Y5
Pineault, S1
Prout, GR2
Keating, MA1
Griffin, PP1
Schiff, SF1
Monfette, JE1
Giguere, M3
Borsanyi, JP3
Lachance, R3
Brochu, M1
Kung, TT1
Mingo, GG1
Siegel, MI1
Watnick, AS1
Johansson, JE3
Andersson, SO2
Beckman, KW2
Zador, G2
Stegmayr, B1
Schnürer, LB1
St-Arnaud, R1
Kelly, SJ1
Lingårdh, G1
Irwin, RJ1

Clinical Trials (21)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A PHASE III TRIAL COMPARING WHOLE PELVIC IRRADIATION FOLLOWED BY A CONEDOWN BOOST TO BOOST IRRADIATION ONLY AND COMPARING NEOADJUVANT TO ADJUVANT TOTAL ANDROGEN SUPPRESSION (TAS)[NCT00769548]Phase 31,322 participants (Actual)Interventional1995-04-30Completed
Phase III Multicenter Randomized Trial of Adjuvant Androgen Deprivation in Combination With Three-dimensional Conformal Radiotherapy Doses in High and Intermediate Risk Localized Prostate Cancer.[NCT02175212]Phase 3362 participants (Actual)Interventional2005-11-30Completed
A Randomised Comparison of Short and Protracted Neoadjuvant Hormonal Therapy Prior to Radiation Therapy of High Risk Localized Prostate Cancer[NCT00003734]Phase 3276 participants (Anticipated)Interventional1998-12-31Active, not recruiting
Implant and External Radiation for Prostate Cancer With or Without Hormonal Therapy: A Prospective Randomized Trial[NCT00243646]Phase 36 participants (Actual)Interventional2004-08-31Terminated (stopped due to poor accrual)
Postoperative Hypofractionated Radiation Therapy and Hormonal Therapy in Patients With Prostate Cancer: A Phase II Trial[NCT04249154]Phase 277 participants (Anticipated)Interventional2019-09-03Recruiting
Phase II Randomized Clinical Trial Comparing 3-D Conformal Radiation Therapy (RT) vs. Intensity Modulated Radiation Therapy in Post- Prostatectomy Prostate Cancer Patients[NCT02678520]Phase 20 participants (Actual)Interventional2015-12-31Withdrawn (stopped due to PI no longer at institution. Study terminated prior to enrolling subjects.)
A Phase III Trial of External Beam of Radiotherapy +/- Total Androgen Suppression for High Risk Clinically Organ-Confined Prostate Cancer[NCT00116220]Phase 3206 participants (Actual)Interventional1995-09-30Completed
A Phase II Study of Proton-Based Radiation Therapy With Elective Pelvic Nodal Irradiation, Concomitant Docetaxel, and Adjuvant Androgen Deprivation for High-Risk Prostate Adenocarcinoma[NCT01040624]77 participants (Actual)Interventional2009-12-31Completed
Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy[NCT00969111]70 participants (Anticipated)Interventional2009-08-31Recruiting
A Phase II Study of Dose-Escalated Proton-Based Radiation Therapy Delivered With a Simultaneous Integrated Boost (SIB) to Intraprostatic Tumors (IPT) Visible on Pretreatment Magnetic Resonance Image[NCT03624660]100 participants (Anticipated)Interventional2018-09-24Recruiting
A PHASE III TRIAL OF THE USE OF LONG TERM TOTAL ANDROGEN SUPPRESSION FOLLOWING NEOADJUVANT HORMONAL CYTOREDUCTION AND RADIOTHERAPY IN LOCALLY ADVANCED CARCINOMA OF THE PROSTATE[NCT00767286]Phase 30 participants InterventionalCompleted
Phase II Trial of Maximal Androgen Deprivation Followed by Conformal External Beam Radiotherapy With Continued Androgen Deprivation for Clinically Localized Prostate Cancer[NCT00003124]Phase 2105 participants (Anticipated)Interventional1997-05-31Completed
Docetaxel and Estramustine Versus Mitoxantrone and Prednisone for Advanced, Hormone Refractory Prostate Cancer[NCT00004001]Phase 3770 participants (Actual)Interventional1999-10-31Completed
ULTRA-HYPO Fractionated (UHF) Compared to Moderate-HYPO Fractionated (MHF) Prostate IGRT With HDR Brachytherapy BOOST : A Phase 1-2 Study.[NCT05786742]205 participants (Anticipated)Interventional2014-04-30Recruiting
Randomized Controlled Clinical Trial of Carbohydrate Restriction Among Men Initiating Androgen Deprivation Therapy For Prostate Cancer[NCT00932672]Phase 245 participants (Actual)Interventional2009-06-30Terminated (stopped due to slow recruitment, lack of funding and PI transferred)
Pelvic Nodes Ultra-Hypo Fractionated Versus Conventionally Fractionated IMRT With HDR Brachytherapy Boost in Prostate Cancer: A Collaborative Multi-institutional Non-inferiority Phase 3 Trial. (PCS-XI)[NCT05820633]500 participants (Anticipated)Interventional2022-09-01Recruiting
Prognostic Value of Androgen Receptor Expression and Mutations Within Oncogenes and Tumor Suppressor Genes in Patients Treated for High Risk Prostate Cancer With Proton Therapy[NCT03296124]0 participants (Actual)Observational2017-12-07Withdrawn (stopped due to This project currently does not have any subjects enrolled due to other PI priorities.)
PROGNOSTIC SIGNIFICANCE OF ENDORECTAL MRI IN PREDICTING OUTCOME AFTER COMBINED RADIATION AND ANDROGEN SUPPRESSION FOR PROSTATE CANCER: A PROSPECTIVE PHASE II STUDY[NCT00002889]Phase 2180 participants (Actual)Interventional1997-05-31Completed
A Phase II Trial of Enzalutamide in Combination With PSA-TRICOM in Patients With Non-Metastatic Castration Sensitive Prostate Cancer[NCT01875250]Phase 238 participants (Actual)Interventional2013-07-22Completed
Collection of Blood From Patients With Prostate Cancer[NCT00923221]1,000 participants (Anticipated)Observational2007-02-28Recruiting
Phase III Study of Hypofractionated, Dose Escalation Radiotherapy vs. Conventional Pelvic Radiation Therapy Followed by HDR Brachy Boost for High Risk Adenocarcinoma of the Prostate (PCS-VI)[NCT02303327]Phase 3296 participants (Anticipated)Interventional2015-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Biochemical Disease Free Survival: Estimated Percentage of Participants With Biochemical Disease-free Survival at 5 Years

Biochemical relapse was defined as the time from inclusion in the study (randomization) until the patient meets criteria for Biochemical failure (Phoenix criteria: PSA nadir plus 2 ng/ml). (NCT02175212)
Timeframe: 5 years

Interventionpercentage of patients (Number)
Long Term Androgen Deprivation90
Short Term Androgen Deprivation81

Cause-specific Survival

Cause-specific survival included all deaths from prostate cancer or treatment complications, and deaths from unknown causes in patients with either active cancer or a previously documented relapse (NCT02175212)
Timeframe: 5 years

Interventionparticipants (Number)
Long Term Androgen Deprivation177
Short Term Androgen Deprivation173

Metastasis Free Survival: Estimated Percentage of Participants With Metastasis-free Survival at 5 Years

Metastasis free survival: defined as the time from inclusion in the study (randomization) until the appearance of distant metastases: a positive result in any of the tests performed (scintigraphy, chest radiography, thorax, abdominal and pelvic CT and MRI). (NCT02175212)
Timeframe: 5 years

Interventionpercentage of participants (Number)
Long Term Androgen Deprivation94
Short Term Androgen Deprivation83

Overall Survival: Estimated Percentage of Participants Alive at 5 Years

Overall Survival: defined as the time that elapses from the patient enters the study until the patient dies from any cause. (NCT02175212)
Timeframe: 5 years

Interventionpercentage of patients (Number)
Long Term Androgen Deprivation95
Short Term Androgen Deprivation86

Late Toxicity

"Defined as the maximal rectal, urinary and cardiovascular (CV) toxicity per patient more than 90 days after completion of RT.~Scoring scales used were the radiation morbidity scoring criteria of the European Organization for Research and Treatment of Cancer-Radiation Therapy Oncology Group (EORTC/RTOG) and the Common Terminology Criteria for Adverse Events (CTCAEs) v 3.0 for the remained toxicity.~CV events were defined according to the World Health Organization criteria" (NCT02175212)
Timeframe: 5 years

,
Interventionpercentage of patients (Number)
Grade 2 of more rectal toxicityGrade 2 of more urinary toxicityCardiovascular
Long Term Androgen Deprivation11.18.217.6
Short Term Androgen Deprivation7.67.37.2

Acute Grade 3 or Higher Treatment-related Toxicity Rate.

Number of participants that experienced acute grade 3 or higher, treatment-related toxicity based on CTCAE version 3.0 criteria. (NCT01040624)
Timeframe: 6 months after the completion of radiation therapy

Interventionparticipants (Number)
HR-A1
HR-B3

Median Testosterone After 84 Days of Enzalutamide

Normal testosterone is 270-1070 nd/dL. (NCT01875250)
Timeframe: 84 days

Interventionng/dl (Median)
All Participants834

Number of Participants With Serious and Non-serious Adverse Events Assessed by the Common Terminology Criteria for Adverse Events (CTCAE v4.0)

Here is the count of participants with serious and non-serious adverse events assessed by the Common Terminology Criteria for Adverse Events (CTCAE v4.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life-threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT01875250)
Timeframe: Date treatment consent signed to date off study, approximately 43 months and 13 days for Arm A, and 78 months and 6 days for Arm B.

InterventionParticipants (Count of Participants)
Arm A - Enzalutamide for 3 Months19
Arm B - Enzalutamide for 3 Months + PSA-TRICOM19

Percent Change in Prostate Specific Antigen (PSA) After 84 Days of Enzalutamide in Course 1

Median PSA change would be considered optimal. (NCT01875250)
Timeframe: 84 days

InterventionPercent change (Median)
Arm A - Enzalutamide for 3 Months-99
Arm B - Enzalutamide for 3 Months + PSA-TRICOM-99

Tumor Growth Rate

Growth rate was measured using the growth rate equation -f(t) = exp (-d*t) + exp (g*t) -1 where exp is the base of the natural algorithm, e = 2.7182 and t is days since treatment started. The tumor growth rate equation measures Prostate Specific Antigen (PSA) rise over time. The UOM is unitless because this is a way to measure PSA kinetics. (NCT01875250)
Timeframe: 7 months

Interventionunitless (Number)
Arm A - Enzalutamide for 3 Months0.031
Arm B - Enzalutamide for 3 Months + PSA-TRICOM0.030

Mean Pretreatment Plasma Vascular Endothelial Growth Factor (VEGF) Concentration 30 Days After the Start of Course 1 and Course 2 of Enzalutamide

VEGF was measured by the enzyme-linked immunosorbent assay (ELISA) assay. The lower limit of quantitation of assay was 9.0 pg/ml. (NCT01875250)
Timeframe: 30 Days After the Start of Course 1 and Course 2 of Enzalutamide

Interventionpg/ml (Mean)
Course 1Course 2
All Participants192165.04

Median Time Until Prostate Specific Antigen (PSA) Recovery From Baseline Following Course 1 and Course 2 of Enzalutamide

PSA recovery is defined as the return above baseline PSA in participants with normal testosterone and non-metastatic, castration sensitive prostate cancer. (NCT01875250)
Timeframe: up to 41 months

InterventionDays (Median)
Course 1Course 2
All Participants224189

Reviews

11 reviews available for flutamide and Adenocarcinoma

ArticleYear
[Prostatic cancer with multiple pulmonary metastases treated successfully with hormonal therapy: a case report].
    Hinyokika kiyo. Acta urologica Japonica, 2002, Volume: 48, Issue:8

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Diethylstilbestrol; Dru

2002
Rotational 3D-conformal radiation therapy (conformation therapy) combined with hormone therapy for the treatment of stage B2/C prostate cancer in Japanese men.
    International journal of radiation oncology, biology, physics, 2003, May-01, Volume: 56, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Ch

2003
Monotherapy in advanced prostate cancer: an overview.
    Experimental oncology, 2004, Volume: 26, Issue:3

    Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Combined Modality T

2004
[Hepatic encephalopathy induced by flutamide administered for the treatment of prostatic cancer].
    Journal d'urologie, 1996, Volume: 102, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Drug Therapy, Combination; Flutamide; Hepatic

1996
[Fulminant liver failure with a fatal outcome due to flutamide].
    Medicina clinica, 1997, Feb-15, Volume: 108, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Bone Neoplasms; Fatal Outcome; Flutamide; Hep

1997
Adenocarcinoma of the prostate with ectopic antidiuretic hormone production: a case report.
    Hinyokika kiyo. Acta urologica Japonica, 2000, Volume: 46, Issue:7

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flutamide; Humans; Inap

2000
[Successful complete androgen blockade (CAB) therapy for prostatic cancer detected from multiple lung metastases: a case report].
    Hinyokika kiyo. Acta urologica Japonica, 2001, Volume: 47, Issue:1

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Drug

2001
[Predicting long-term survival, and the need for hormonal therapy: a meta-analysis of RTOG prostate cancer trials].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2001, Volume: 5, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Clinical Trials as Topic; C

2001
Assessing meaningful change in quality of life over time: a users' guide for clinicians.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:6

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Clinical Competence; Clinical

2002
[Endometrioid adenocarcinoma of the prostate. Apropos of a case, review of the literature].
    Journal d'urologie, 1992, Volume: 98, Issue:2

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Flutamide; Humans; Leuprolide;

1992
Combination therapy with flutamide and castration: its benefits at various stages of prostate cancer.
    Progress in clinical and biological research, 1989, Volume: 303

    Topics: Adenocarcinoma; Anilides; Canada; Clinical Trials as Topic; Combined Modality Therapy; Flutamide; Hu

1989

Trials

59 trials available for flutamide and Adenocarcinoma

ArticleYear
Duration of Androgen Deprivation in Locally Advanced Prostate Cancer: Long-Term Update of NRG Oncology RTOG 9202.
    International journal of radiation oncology, biology, physics, 2017, 06-01, Volume: 98, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Combined Modality Therapy; Dis

2017
Sequence of hormonal therapy and radiotherapy field size in unfavourable, localised prostate cancer (NRG/RTOG 9413): long-term results of a randomised, phase 3 trial.
    The Lancet. Oncology, 2018, Volume: 19, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Canada; Chemoradiotherapy; Dose Frac

2018
High-dose radiotherapy with short-term or long-term androgen deprivation in localised prostate cancer (DART01/05 GICOR): a randomised, controlled, phase 3 trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents, Horm

2015
Importance of Local Control in Early-Stage Prostate Cancer: Outcomes of Patients With Positive Post-Radiation Therapy Biopsy Results Treated in RTOG 9408.
    International journal of radiation oncology, biology, physics, 2015, Jul-15, Volume: 92, Issue:4

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Biopsy; Combined Modality Therapy; Di

2015
Risk of prostate cancer recurrence in men treated with radiation alone or in conjunction with combined or less than combined androgen suppression therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jun-20, Volume: 26, Issue:18

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Combined Chemotherapy

2008
Is biochemical response more important than duration of neoadjuvant hormone therapy before radiotherapy for clinically localized prostate cancer? An analysis of the 3- versus 8-month randomized trial.
    International journal of radiation oncology, biology, physics, 2010, Jan-01, Volume: 76, Issue:1

    Topics: Adenocarcinoma; Aged; Analysis of Variance; Androgen Antagonists; Antineoplastic Agents, Hormonal; D

2010
Benefit of whole pelvic radiotherapy combined with neoadjuvant androgen deprivation for the high-risk prostate cancer.
    Journal of biomedicine & biotechnology, 2009, Volume: 2009

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flutamide; Goserelin; H

2009
A randomized trial (Irish clinical oncology research group 97-01) comparing short versus protracted neoadjuvant hormonal therapy before radiotherapy for localized prostate cancer.
    International journal of radiation oncology, biology, physics, 2011, Sep-01, Volume: 81, Issue:1

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Disease-Free Survival;

2011
Efficacy of peripheral androgen blockade in prostate cancer patients with biochemical failure after definitive local therapy: results of Cancer and Leukemia Group B (CALGB) 9782.
    Cancer, 2012, Sep-01, Volume: 118, Issue:17

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineo

2012
Addition of radiotherapy to long-term androgen deprivation in locally advanced prostate cancer: an open randomised phase 3 trial.
    European urology, 2012, Volume: 62, Issue:2

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Chemoradiotherapy; Dise

2012
Metastatic carcinoma of the prostate: identifying prognostic groups using recursive partitioning.
    The Journal of urology, 2003, Volume: 169, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormona

2003
Variation in chromogranin A serum levels during intermittent versus continuous androgen deprivation therapy for prostate adenocarcinoma.
    The Prostate, 2003, May-15, Volume: 55, Issue:3

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined

2003
Finasteride and flutamide therapy in patients with advanced prostate cancer: response to subsequent castration and long-term follow-up.
    Urology, 2003, Volume: 62, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Androgen Antagonists; Androgens; Antineoplastic Agents, Hormonal; Antin

2003
Combination of low-dose flutamide and finasteride for PSA-only recurrent prostate cancer after primary therapy.
    Urology, 2003, Volume: 62, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hor

2003
Ten-year survival in patients with metastatic prostate cancer.
    Clinical prostate cancer, 2003, Volume: 2, Issue:1

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Disease-Free Survival; Double-Blind Method; Flutamide; F

2003
Intermittent versus continuous total androgen blockade in the treatment of patients with advanced hormone-naive prostate cancer: results of a prospective randomized multicenter trial.
    Clinical prostate cancer, 2002, Volume: 1, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; D

2002
Intermittent androgen suppression for locally advanced and metastatic prostate cancer: preliminary report of a prospective multicenter study.
    Urology, 2004, Volume: 64, Issue:2

    Topics: Adenocarcinoma; Aged; Androgens; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Disease Progres

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.
    JAMA, 2004, Aug-18, Volume: 292, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2004
Flutamide in unresectable pancreatic adenocarcinoma: a randomized, double-blind, placebo-controlled trial.
    Investigational new drugs, 2006, Volume: 24, Issue:3

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Double-Blind Method; Female;

2006
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Disease-Free Survival; Flutamide; Gos

2005
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Disease-Free Survival; Flutamide; Gos

2005
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Disease-Free Survival; Flutamide; Gos

2005
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Disease-Free Survival; Flutamide; Gos

2005
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Disease-Free Survival; Flutamide; Gos

2005
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Disease-Free Survival; Flutamide; Gos

2005
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Disease-Free Survival; Flutamide; Gos

2005
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Disease-Free Survival; Flutamide; Gos

2005
Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Disease-Free Survival; Flutamide; Gos

2005
Phase II study of neoadjuvant androgen deprivation followed by external-beam radiotherapy with 9 months of androgen deprivation for intermediate- to high-risk localized prostate cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jan-01, Volume: 25, Issue:1

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Disease-Free Survival; Flutam

2007
Early effects of pharmacological androgen deprivation in human prostate cancer.
    BJU international, 2007, Volume: 99, Issue:1

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Flutamide; Humans; Leuprolide; Male; Neoplasms, Hormone-

2007
Association of body mass index with response and survival in men with metastatic prostate cancer: Southwest Oncology Group trials 8894 and 9916.
    The Journal of urology, 2007, Volume: 178, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Body Mass Index; Disease-F

2007
Long-term treatment sequelae after external beam irradiation with or without hormonal manipulation for adenocarcinoma of the prostate: analysis of radiation therapy oncology group studies 85-31, 86-10, and 92-02.
    International journal of radiation oncology, biology, physics, 2008, Feb-01, Volume: 70, Issue:2

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Combined Modality Therapy; Flutamide; Follow-Up Studies;

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.
    JAMA, 2008, Jan-23, Volume: 299, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Caus

2008
p53 protein expression status and recurrence in men treated with radiation and androgen suppression therapy for higher-risk prostate cancer: a prospective phase II Cancer and Leukemia Group B Study (CALGB 9682).
    Urology, 2008, Volume: 71, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Mi

2008
Antiandrogen withdrawal in castrate-refractory prostate cancer: a Southwest Oncology Group trial (SWOG 9426).
    Cancer, 2008, Volume: 112, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Bone Neoplasms; Disease-Fre

2008
Experience with flutamide in patients with advanced prostatic cancer without prior endocrine therapy.
    Cancer, 1984, Aug-15, Volume: 54, Issue:4

    Topics: Acid Phosphatase; Adenocarcinoma; Adult; Aged; Anilides; Bone Neoplasms; Clinical Trials as Topic; F

1984
Neoadjuvant hormonal therapy in stage C adenocarcinoma of the prostate.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1993, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combin

1993
Clinical and pathobiological effects of neoadjuvant total androgen ablation therapy on clinically localized prostatic adenocarcinoma.
    The American journal of surgical pathology, 1994, Volume: 18, Issue:10

    Topics: Adenocarcinoma; Cell Division; Combined Modality Therapy; Diploidy; Flutamide; Goserelin; Humans; Ma

1994
A controlled trial of bicalutamide versus flutamide, each in combination with luteinizing hormone-releasing hormone analogue therapy, in patients with advanced prostate cancer. Casodex Combination Study Group.
    Urology, 1995, Volume: 45, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anilides; Antineoplastic Agents; Antineoplastic Comb

1995
High failure rate associated with long-term follow-up of neoadjuvant androgen deprivation followed by radical prostatectomy for stage C prostatic cancer.
    British journal of urology, 1995, Volume: 75, Issue:6

    Topics: Adenocarcinoma; Aged; Combined Modality Therapy; Disease-Free Survival; Flutamide; Follow-Up Studies

1995
Androgen deprivation with radiation therapy compared with radiation therapy alone for locally advanced prostatic carcinoma: a randomized comparative trial of the Radiation Therapy Oncology Group.
    Urology, 1995, Volume: 45, Issue:4

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Combined Modality Therapy; Flutamide; Goserelin; Humans; Ma

1995
Downstaging of localized prostate cancer by neoadjuvant therapy with flutamide and lupron: the first controlled and randomized trial.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1993, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combin

1993
Decrease of prostatic intraepithelial neoplasia following androgen deprivation therapy in patients with stage T3 carcinoma treated by radical prostatectomy.
    Urology, 1994, Volume: 44, Issue:1

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Carcinoma in Situ; Case-Control Studies; Combined Modali

1994
The use of flutamide in hormone-refractory metastatic prostate cancer.
    Cancer, 1993, Dec-15, Volume: 72, Issue:12 Suppl

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Double-Blind Method; Flutamide; Huma

1993
Characterization of patients with androgen-independent prostatic carcinoma whose serum prostate specific antigen decreased following flutamide withdrawal.
    The Journal of urology, 1996, Volume: 155, Issue:2

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Flutamide; Humans; Male; M

1996
[Prognosis significance of prostatic markers in patients with prostatic adenocarcinoma undergoing total hormonal blockade].
    Actas urologicas espanolas, 1995, Volume: 19, Issue:5

    Topics: Acid Phosphatase; Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Fluta

1995
Histopathological effects of androgen deprivation in prostatic cancer.
    Seminars in urologic oncology, 1996, Volume: 14, Issue:2 Suppl 2

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Fl

1996
A controlled trial of bicalutamide versus flutamide, each in combination with luteinizing hormone-releasing hormone analogue therapy, in patients with advanced prostate carcinoma. Analysis of time to progression. CASODEX Combination Study Group.
    Cancer, 1996, Nov-15, Volume: 78, Issue:10

    Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Double-Blind Method

1996
[Histologic regression of localized prostatic tumor with neoadjuvant hormonal therapy].
    Archivos espanoles de urologia, 1996, Volume: 49, Issue:8

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Combined Modality Therapy; Flutamide; Gonadotropin-Relea

1996
Neoadjuvant hormonal therapy: the Canadian experience.
    Urology, 1997, Volume: 49, Issue:3A Suppl

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Canada; Chemotherapy, Adjuvant; Drug Therapy, Combinatio

1997
Finasteride and flutamide as potency-sparing androgen-ablative therapy for advanced adenocarcinoma of the prostate.
    Urology, 1997, Volume: 49, Issue:6

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Enzyme Inhibitors; Erectile Dysfunction; Finasteride; Fl

1997
[Neoadjuvant combined hormonal therapy and radiotherapy with external beam irradiation in prostatic carcinoma].
    La Radiologia medica, 1997, Volume: 93, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Flutamide; Follow-

1997
Phase II study of flutamide as second line chemotherapy in patients with advanced pancreatic cancer.
    Investigational new drugs, 1997, Volume: 15, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Female; Flutamide;

1997
Bilateral orchiectomy with or without flutamide for metastatic prostate cancer.
    The New England journal of medicine, 1998, Oct-08, Volume: 339, Issue:15

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Bone Neoplasms; Combined Modal

1998
Exploratory analysis on the effect of race on clinical outcome in patients with advanced prostate cancer receiving bicalutamide or flutamide, each in combination with LHRH analogues. The Casodex Combination Study Group.
    The Prostate, 1999, Sep-01, Volume: 40, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agent

1999
[Primary treatment for stage D2 prostate cancer: a randomized study of combined androgen blockade alone versus combined with UFT].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antimetabolites, Antineoplastic; Anti

1999
A prospective randomized multicenter study of chlormadinone acetate versus flutamide in total androgen blockade for prostate cancer.
    Japanese journal of clinical oncology, 2000, Volume: 30, Issue:9

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Chlormadinone Acetate;

2000
Treatment of localized prostate cancer with intermittent triple androgen blockade: preliminary results in 110 consecutive patients.
    The oncologist, 2001, Volume: 6, Issue:2

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents, Horm

2001
Optimal starting time for flutamide to prevent disease flare in prostate cancer patients treated with a gonadotropin-releasing hormone agonist.
    Urologia internationalis, 2001, Volume: 66, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flut

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Cause of Death; Chemotherapy,

2001
[The role of LH-RH analogues in the treatment of prostate cancer. Report of a conference organized by ICI-Pharma laboratories (part 2)].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1991, Volume: 1, Issue:2

    Topics: Adenocarcinoma; Drug Therapy, Combination; Flutamide; Goserelin; Humans; Male; Neoplasm Staging; Orc

1991
A pilot trial of chemohormonal therapy for metastatic prostate carcinoma.
    Cancer, 1992, Jan-01, Volume: 69, Issue:1

    Topics: Adenocarcinoma; Aged; Androgens; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Drug E

1992
Combination therapy with flutamide and medical (LHRH agonist) or surgical castration in advanced prostate cancer: 7-year clinical experience.
    The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Canada; Flutamide; H

1990
Combination therapy with flutamide and castration: its benefits at various stages of prostate cancer.
    Progress in clinical and biological research, 1989, Volume: 303

    Topics: Adenocarcinoma; Anilides; Canada; Clinical Trials as Topic; Combined Modality Therapy; Flutamide; Hu

1989
Clinical evaluation with long-term follow-up of flutamide and estramustine as initial treatment of metastatic carcinoma of the prostate.
    American journal of clinical oncology, 1988, Volume: 11 Suppl 2

    Topics: Adenocarcinoma; Aged; Anilides; Bone Neoplasms; Estramustine; Flutamide; Follow-Up Studies; Humans;

1988
Combination therapy with flutamide and castration (orchiectomy or LHRH agonist): the minimal endocrine therapy in both untreated and previously treated patients with advanced prostate cancer.
    Progress in clinical and biological research, 1988, Volume: 260

    Topics: Adenocarcinoma; Anilides; Antineoplastic Agents; Clinical Trials as Topic; Combined Modality Therapy

1988
Clinical evaluation of flutamide and estramustine as initial treatment of metastatic carcinoma of prostate.
    Urology, 1987, Volume: 29, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anilides; Bone Neoplasms; Estramustine; Flutamide; Humans;

1987

Other Studies

126 other studies available for flutamide and Adenocarcinoma

ArticleYear
PCDH1, a poor prognostic biomarker and potential target for pancreatic adenocarcinoma metastatic therapy.
    BMC cancer, 2023, Nov-13, Volume: 23, Issue:1

    Topics: Adenocarcinoma; Biomarkers; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Ne

2023
Predictors of poor response to first-generation anti-androgens as criteria for alternate treatments for patients with non-metastatic castration-resistant prostate cancer.
    International urology and nephrology, 2020, Volume: 52, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Chlormadinone Acetate; Flut

2020
Status of the Microcirculatory Network as a Factor of Prognosis and Evaluation of Therapeutic Efficiency in Prostate Cancer Treated by High-Intensity Focused Ultrasound in Combination with Androgen Deprivation.
    Bulletin of experimental biology and medicine, 2018, Volume: 165, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antigens, CD34; Antineoplastic Agents

2018
Partial androgen suppression consequent to increased secretion of adrenal androgens in a patient with prostate cancer treated with long-acting GnRH agonists.
    Prostate cancer and prostatic diseases, 2009, Volume: 12, Issue:1

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Androgens; Anilides; Buserelin; Diarrhea; Flutamide; Gas

2009
Adrenal androgen levels as predictors of outcome in castration-resistant prostate cancer patients treated with combined androgen blockade using flutamide as a second-line anti-androgen.
    International journal of urology : official journal of the Japanese Urological Association, 2010, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Adrenal Glands; Aged; Aged, 80 and over; Androgen Antagonists; Androgens; Cell Line,

2010
[Spontaneous complete remission in two patients with chronic lymphocytic leukemia].
    Medicina clinica, 2011, Jul-23, Volume: 137, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Female; Flutamide; Human

2011
Fluorinated and pegylated polyaspartamide derivatives to increase solubility and efficacy of Flutamide.
    Journal of drug targeting, 2012, Volume: 20, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Chromatograph

2012
The moving landscape of locally advanced prostate cancer: combination of external irradiation and endocrine treatment and/or multimodal approach.
    European urology, 2012, Volume: 62, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Flutamide; Humans; Leuprolide; Male; Prostatic Neop

2012
Neoadjuvant hormonal therapy prior to radical prostatectomy: evaluation of pathological downstaging and biochemical relapse.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2002, Volume: 69, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Chlormadinone Acetate; Flu

2002
Impact of a novel neoadjuvant and adjuvant hormone-deprivation approach on quality of life, voiding function, and sexual function after prostate brachytherapy.
    Cancer, 2003, Mar-01, Volume: 97, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Aged; Androgen Antagonists; Anilides; Brachytherapy; C

2003
Androgen deprivation in men with prostate cancer is associated with an increased rate of bone loss.
    Prostate cancer and prostatic diseases, 2002, Volume: 5, Issue:4

    Topics: Absorptiometry, Photon; Adenocarcinoma; Aged; Amino Acids; Androgen Antagonists; Androgens; Anilides

2002
Flutamide-induced photosensitivity: is it a forme fruste of lupus?
    The British journal of dermatology, 2003, Volume: 148, Issue:3

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flutamide; Humans; Lupu

2003
[Neuroendocrine differentiation in adenocarcinoma of the prostate with progression of disease during hormonal treatment: a report of two cases].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2003, Volume: 94, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Carcinoma, Neuroendocrine; Cell Differentiati

2003
Impact of hormone therapy when combined with external beam radiotherapy for early-stage, intermediate-, or high-risk prostate cancer.
    American journal of clinical oncology, 2003, Volume: 26, Issue:4

    Topics: Adenocarcinoma; Aged; Anilides; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Flutamide;

2003
Prostate carcinoma presenting as multiple pulmonary nodules in an asymptomatic patient with a history of testicular nonseminomatous germ cell tumor.
    Urology, 2003, Volume: 62, Issue:4

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protoco

2003
Cholestatic jaundice as a paraneoplastic manifestation of prostate adenocarcinoma.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:6

    Topics: Adenocarcinoma; Aged; Alkaline Phosphatase; Antineoplastic Agents, Hormonal; Bilirubin; Biomarkers,

2003
Biochemical remission after resection of prostate cancer lung metastasis.
    Urology, 2004, Volume: 63, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Combined Modality Therapy;

2004
Proteasome inhibitors and their combination with antiandrogens: effects on apoptosis, cellular proliferation and viability of prostatic adenocarcinoma cell cultures.
    Prostate cancer and prostatic diseases, 2004, Volume: 7, Issue:2

    Topics: Adenocarcinoma; Androgen Antagonists; Apoptosis; Cell Division; Cell Survival; Cysteine Proteinase I

2004
Interstitial pneumonitis related to flutamide monotherapy for prostate cancer.
    International journal of urology : official journal of the Japanese Urological Association, 2004, Volume: 11, Issue:9

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Flutamide; Humans; Lung Di

2004
Anemia in patients on combined androgen block therapy for prostate cancer.
    Asian journal of andrology, 2004, Volume: 6, Issue:4

    Topics: Adenocarcinoma; Adult; Androgen Antagonists; Anemia; Antineoplastic Agents, Hormonal; Combined Modal

2004
[Experience in treating advanced prostate cancer with bladder outlet obstruction].
    Ai zheng = Aizheng = Chinese journal of cancer, 2005, Volume: 24, Issue:10

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antigens, Neoplasm; Flutamide; Humans

2005
Microscopic polyangiitis complicated by the development of prostate cancer and flutamide-induced hepatitis.
    International urology and nephrology, 2005, Volume: 37, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Flutamide; Humans; Male; Prostatic Neoplasms;

2005
Long-term hormone therapy and radiation is cost-effective for patients with locally advanced prostate carcinoma.
    Cancer, 2006, Jan-01, Volume: 106, Issue:1

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Co

2006
Possibility of recovery of estrogen sensitivity following high-dose glucocorticoid therapy in a patient with hormone-refractory prostate cancer.
    International journal of clinical oncology, 2006, Volume: 11, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocol

2006
Results of radiation therapy combined with neoadjuvant hormonal therapy for stage III prostate cancer: comparison of two different definitions of PSA failure.
    International journal of clinical oncology, 2006, Volume: 11, Issue:5

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Biomarkers, Tumor; Cohort Studies; Drug Therapy, Combina

2006
[Bone metastasis of prostatic cancer imitating Paget's sarcoma].
    Deutsche medizinische Wochenschrift (1946), 2006, Nov-10, Volume: 131, Issue:45

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Bone Density Conservation Agents; Bone Neopla

2006
Ligand-specific dynamics of the androgen receptor at its response element in living cells.
    Molecular and cellular biology, 2007, Volume: 27, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Animals; Cell Line, Tumor; Chromatin Asse

2007
Suppressive effects of antiandrogens, finasteride and flutamide on development of prostatic lesions in a transgenic rat model.
    Prostate cancer and prostatic diseases, 2007, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Androgen Antagonists; Animals; Animals, Genetically Modified; Antigens, Viral, Tumor

2007
Eliciting patient preferences for hormonal therapy options in the treatment of metastatic prostate cancer.
    Prostate cancer and prostatic diseases, 2008, Volume: 11, Issue:2

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Choice Behavi

2008
Does small-cell phenotype predict the natural history of prostate cancer? A case study in disease behavior.
    Nature clinical practice. Oncology, 2007, Volume: 4, Issue:9

    Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Antineoplastic Agents; Antineoplastic Agents, Hormon

2007
Suspected cross-hepatotoxicity of flutamide and cyproterone acetate.
    Liver international : official journal of the International Association for the Study of the Liver, 2007, Volume: 27, Issue:8

    Topics: Acute Disease; Adenocarcinoma; Adrenal Cortex Hormones; Aged; Androgen Antagonists; Antineoplastic A

2007
[Mediastinal lymph nodes during the course of a metastatic prostate cancer].
    Actas urologicas espanolas, 2007, Volume: 31, Issue:6

    Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Antineoplastic Combined Chemotherapy Protocols; Bon

2007
Prostate-cancer-specific survival and clinical progression-free survival in men with prostate cancer treated intermittently with testosterone-inactivating pharmaceuticals.
    Urology, 2007, Volume: 70, Issue:3

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Combined Moda

2007
The influence of androgens, anti-androgens, and castration on cell proliferation in the jejunal and colonic crypt epithelia, and in dimethylhydrazine-induced adenocarcinoma of rat colon.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1982, Volume: 38, Issue:3

    Topics: Adenocarcinoma; Anilides; Animals; Castration; Cell Division; Colon; Colonic Neoplasms; Dimethylhydr

1982
Newer methods of hormonal therapy for prostate cancer.
    Urology, 1984, Volume: 24, Issue:5 Suppl

    Topics: Adenocarcinoma; Aminoglutethimide; Androgen Antagonists; Bone Neoplasms; Buserelin; Flutamide; Gonad

1984
Estrogen, progesterone, and androgen-binding sites in renal cell carcinoma. Observations obtained in Phase II trial of flutamide.
    Cancer, 1984, Aug-01, Volume: 54, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Anilides; Binding Sites; Dihydrotestosterone; Drug Evaluation; Estradio

1984
Concepts in prostatic cancer biology: Dunning R-3327 H, HI, and AT tumors.
    Progress in clinical and biological research, 1980, Volume: 37

    Topics: Acid Phosphatase; Adenocarcinoma; Animals; Castration; Diethylstilbestrol; Disease Models, Animal; F

1980
The potential for normal tissue dose reduction with neoadjuvant hormonal therapy in conformal treatment planning for stage C prostate cancer.
    International journal of radiation oncology, biology, physics, 1995, Dec-01, Volume: 33, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Flutamide; Goserelin; Human

1995
Adenocarcinoma of the prostate metastatic to the choroid of the eye.
    The Prostate, 1995, Volume: 27, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Choroid Neoplasms; Flutamide; Humans; Leuprol

1995
Massive locally extensive prostate cancer.
    Urology, 1994, Volume: 43, Issue:2

    Topics: Adenocarcinoma; Aged; Combined Modality Therapy; Constipation; Flutamide; Humans; Leuprolide; Male;

1994
Diagnosis of low back pain, secondary to prostate metastasis to the lumbar spine, by digital rectal examination and serum prostate-specific antigen.
    Journal of manipulative and physiological therapeutics, 1994, Volume: 17, Issue:2

    Topics: Adenocarcinoma; Aged; Back Pain; Flutamide; Humans; Lumbar Vertebrae; Male; Orchiectomy; Postoperati

1994
Metastatic prostate cancer pulmonary nodules: beneficial effects of combination therapy and subsequent withdrawal of flutamide.
    The Prostate, 1994, Volume: 24, Issue:5

    Topics: Acid Phosphatase; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bo

1994
Neoadjuvant hormonal deprivation before radical prostatectomy.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1993, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Biopsy;

1993
Effects of combination endocrine treatment on normal prostate, prostatic intraepithelial neoplasia, and prostatic adenocarcinoma.
    Journal of clinical pathology, 1994, Volume: 47, Issue:10

    Topics: Adenocarcinoma; Aged; Carcinoma in Situ; Drug Therapy, Combination; Flutamide; Gonadotropin-Releasin

1994
Morphologic and immunohistochemical changes in prostate cancer after preoperative hormonal therapy. A comparative study of radical prostatectomies.
    Cancer, 1994, Dec-15, Volume: 74, Issue:12

    Topics: Acid Phosphatase; Adenocarcinoma; Aged; Chemotherapy, Adjuvant; Chromogranin A; Chromogranins; Estra

1994
Influence of radiotherapy on node-positive prostate cancer treated with androgen ablation.
    International journal of radiation oncology, biology, physics, 1995, Jan-01, Volume: 31, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Diethylstilbestrol; Flutamide; Gonadotropin-Releasing Hormone; Humans;

1995
Clinical trials referral resource. Prostate cancer.
    Oncology (Williston Park, N.Y.), 1994, Volume: 8, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Comb

1994
TAG-72 expression in primary, metastatic and hormonally treated prostate cancer as defined by monoclonal antibody CC49.
    The Journal of urology, 1995, Volume: 153, Issue:5

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antigens, Neoplasm; Bone Neoplasms; Flutamide; Glycoproteins

1995
Combined hormonal and radiation therapy for lymph node-positive prostate cancer.
    Urology, 1995, Volume: 46, Issue:2

    Topics: Adenocarcinoma; Aged; Combined Modality Therapy; Diethylstilbestrol; Disease-Free Survival; Flutamid

1995
Effect of medroxyprogesterone acetate (MPA) and serum factors on cell proliferation in primary cultures of an MPA-induced mammary adenocarcinoma.
    Breast cancer research and treatment, 1995, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Androgen Antagonists; Animals; Blood Physiological Phenomena; Cell Division; Dexamet

1995
Response to flutamide withdrawal in advanced prostate cancer in progression under combination therapy.
    The Journal of urology, 1993, Volume: 150, Issue:3

    Topics: Adenocarcinoma; Combined Modality Therapy; Flutamide; Humans; Male; Neoplasm Staging; Prostate-Speci

1993
[Bilateral testicular metastasis of an adenocarcinoma of the prostate].
    Annales d'urologie, 1994, Volume: 28, Issue:5

    Topics: Adenocarcinoma; Aged; Bone Neoplasms; Combined Modality Therapy; Flutamide; Humans; Male; Orchiectom

1994
Squamous cell carcinoma of the prostate: a transformation from adenocarcinoma after the use of a luteinizing hormone-releasing hormone agonist and flutamide.
    Urology, 1995, Volume: 45, Issue:2

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Flutamide; Humans; Leupro

1995
Prostatic invasive adenocarcinoma. Effect of combination endocrine therapy (LHRH agonist and flutamide) on the expression and location of proliferating cell nuclear antigen (PCNA).
    Pathology, research and practice, 1993, Volume: 189, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Flutamide; Gonadotropin-Releasing Ho

1993
[Fluamide withdrawal syndrome].
    Actas urologicas espanolas, 1994, Volume: 18, Issue:6

    Topics: Adenocarcinoma; Aged; Flutamide; Humans; Male; Prostatic Neoplasms; Substance Withdrawal Syndrome

1994
Neoadjuvant hormonal therapy and radical prostatectomy for clinical stage C carcinoma of the prostate.
    British journal of urology, 1994, Volume: 73, Issue:5

    Topics: Adenocarcinoma; Aged; Chemotherapy, Adjuvant; Diethylstilbestrol; Flutamide; Humans; Leuprolide; Mal

1994
Hormonal ablation as effective therapy for carcinomatous meningitis from prostatic carcinoma.
    Cancer, 1994, Apr-01, Volume: 73, Issue:7

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Dexameth

1994
Malignant pleural effusion from prostatic adenocarcinoma resolved with hormonal therapy.
    Chest, 1994, Volume: 105, Issue:5

    Topics: Adenocarcinoma; Aged; Flutamide; Humans; Leuprolide; Male; Pleural Effusion, Malignant; Pleural Neop

1994
Effects of antiandrogens on transformation and transcription activation of wild-type and mutated (LNCaP) androgen receptors.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:6

    Topics: Adenocarcinoma; Alanine; Amino Acid Sequence; Androgen Antagonists; Anilides; Animals; Blotting, Wes

1993
Cholestatic hepatitis following flutamide.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:9

    Topics: Adenocarcinoma; Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Flutamide;

1993
Metastatic carcinoma of the prostate presenting as a superior vena cava syndrome.
    Chest, 1993, Volume: 104, Issue:4

    Topics: Adenocarcinoma; Aged; Biopsy; Flutamide; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Prostatic

1993
Maximum androgen deprivation prior to radical retropubic prostatectomy in patients with stage T3 adenocarcinoma of the prostate.
    European urology, 1995, Volume: 28, Issue:3

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Combined Modality Thera

1995
Florid xanthomatous pelvic lymph node reaction to metastatic prostatic adenocarcinoma. A sequela of preoperative androgen deprivation therapy.
    Archives of pathology & laboratory medicine, 1996, Volume: 120, Issue:1

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protoco

1996
Flutamide-induced liver toxicity including fatal hepatic necrosis.
    International journal of radiation oncology, biology, physics, 1996, Mar-01, Volume: 34, Issue:4

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flutamide; Humans; Live

1996
Androgen receptor modulation in benign human prostatic tissue and prostatic adenocarcinoma during neoadjuvant endocrine combination therapy.
    The Prostate, 1996, Volume: 28, Issue:4

    Topics: Adenocarcinoma; Androgen Antagonists; Drug Therapy, Combination; Epithelial Cells; Epithelium; Fluta

1996
[Fulminant hepatitis caused by flutamide].
    Gastroenterologie clinique et biologique, 1996, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Chemical and Drug Induced Liver Injury; Fatal

1996
Flutamide-induced toxic hepatitis. Potential utility of ursodeoxycholic acid administration in toxic hepatitis.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:11

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Ch

1996
Effects of neoadjuvant androgen deprivation therapy on prostatic cancer.
    European urology, 1996, Volume: 30 Suppl 1

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Case-Control Studies; Chemotherapy, Adjuvant; Flutamide;

1996
p53 status and prognosis of locally advanced prostatic adenocarcinoma: a study based on RTOG 8610.
    Journal of the National Cancer Institute, 1997, Jan-15, Volume: 89, Issue:2

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Cl

1997
Health-related quality of life among patients with metastatic prostate cancer.
    Urology, 1997, Volume: 49, Issue:2

    Topics: Adenocarcinoma; Aged; Analysis of Variance; Androgen Antagonists; Antineoplastic Combined Chemothera

1997
Effect of turosteride, a 5 alpha-reductase inhibitor, on the Dunning R3327 rat prostatic carcinoma.
    The Prostate, 1997, Feb-01, Volume: 30, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androstenedione; Animals; Antineoplastic Agents, Hormo

1997
Early endocrine therapy versus radical prostatectomy combined with early endocrine therapy for stage D1 prostate cancer.
    British journal of urology, 1997, Volume: 79, Issue:2

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Disease Progressio

1997
[Total androgen blockade for prostate cancer].
    Hinyokika kiyo. Acta urologica Japonica, 1997, Volume: 43, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Flutamide; Gonadotropin-Releasing Hor

1997
Flutamide withdrawal plus hydrocortisone resulted in clinical complete response in a patient with prostate carcinoma.
    Cancer, 1997, May-15, Volume: 79, Issue:10

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Anti-Inflammatory Agents; Antineoplastic Agents, Hormona

1997
Immunocytochemical monitoring of micrometastatic disease: reduction of prostate cancer cells in bone marrow by androgen deprivation.
    International journal of cancer, 1997, May-16, Volume: 71, Issue:4

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemo

1997
The prognostic value of neuroendocrine differentiation in adenocarcinoma of the prostate in relation to progression of disease after endocrine therapy.
    The Journal of urology, 1997, Volume: 158, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Cell Differentiation; Dise

1997
Detection of apoptosis by the TUNEL technique in clinically localised prostatic cancer before and after combined endocrine therapy.
    Journal of clinical pathology, 1997, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Flutamide; Humans;

1997
Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:4

    Topics: Adenocarcinoma; Alkaline Phosphatase; Androgen Antagonists; Androgens; Breast Neoplasms; Cyproterone

1997
Acute renal failure in a patient receiving treatment with suramin.
    American journal of clinical oncology, 1997, Volume: 20, Issue:4

    Topics: Acute Kidney Injury; Adenocarcinoma; Androgen Antagonists; Anti-Inflammatory Agents; Antineoplastic

1997
Metastatic prostatic adenocarcinoma presenting as a pituitary mass: shrinkage of the lesion and clinical improvement with medical treatment.
    The Prostate, 1997, Sep-01, Volume: 32, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Neoplasms; Diagno

1997
[Effect of complete androgen block before radical prostatectomy for cancer of the prostate].
    Archivos espanoles de urologia, 1997, Volume: 50, Issue:4

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant;

1997
Neuroendocrine cells in benign prostatic hyperplasia and prostatic carcinoma: effect of hormonal treatment.
    Urologia internationalis, 1997, Volume: 59, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biomarkers, Tumor;

1997
Localized amyloidosis of the seminal vesicle. Possible association with hormonally treated prostatic adenocarcinoma.
    Archives of pathology & laboratory medicine, 1997, Volume: 121, Issue:12

    Topics: Adenocarcinoma; Aged; Amyloidosis; Androgen Antagonists; Antineoplastic Agents, Hormonal; beta 2-Mic

1997
Pseudomyxoma ovariilike posttherapeutic alteration in prostatic adenocarcinoma: a distinctive pattern in patients receiving neoadjuvant androgen ablation therapy.
    The American journal of surgical pathology, 1998, Volume: 22, Issue:3

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Female; Flutamide; Huma

1998
[Combination effect of flutamide and leuprorelin acetate on growth of Dunning R3327-H prostatic adenocarcinoma in rats].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:4

    Topics: Adenocarcinoma; Androgen Antagonists; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combi

1998
Flutamide induced lupus.
    The Journal of urology, 1998, Volume: 159, Issue:6

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Flutamide; Humans; Lupus Erythematosus, Systemic; Male;

1998
Outpatient ultrasound-guided palladium 103 brachytherapy for localized adenocarcinoma of the prostate: a preliminary report of 434 patients.
    Urology, 1998, Volume: 51, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Ambulatory Care; Androgen Antagonists; Antineoplastic Agent

1998
Progesterone receptor involvement in independent tumor growth in MPA-induced murine mammary adenocarcinomas.
    The Journal of steroid biochemistry and molecular biology, 1999, Volume: 68, Issue:1-2

    Topics: Adenocarcinoma; Androgens; Animals; Binding Sites; Estradiol; Female; Flutamide; Glucocorticoids; Go

1999
Correlation between proliferation, apoptosis, and angiogenesis in prostate carcinoma and their relation to androgen ablation.
    Cancer, 1999, Apr-15, Volume: 85, Issue:8

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Androgens; Antigens, Neoplasm; Antineoplastic Agents, Ho

1999
[Fatal hepatic failure following hepatitis caused by flutamide: a case report].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1999, Volume: 90, Issue:5

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Animals; Antineoplastic Agents, Hormonal; Fatal Outcome;

1999
[Serum concentrations of flutamide and goserelin in a prostate cancer patient with obstructive nephropathy: a case report].
    Hinyokika kiyo. Acta urologica Japonica, 1999, Volume: 45, Issue:8

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Flutamide; Goserelin; H

1999
["Evanescent" prostate carcinoma].
    Actas urologicas espanolas, 1999, Volume: 23, Issue:8

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Biopsy, Needle; Combine

1999
Apoptosis, mitosis, p53, bcl(2), Ki-67 and clinical outcome in prostate carcinoma treated by androgen ablation.
    Urologia internationalis, 1999, Volume: 63, Issue:2

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Apoptosis; Flutamide; H

1999
Examination of selected food additives and organochlorine food contaminants for androgenic activity in vitro.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 53, Issue:2

    Topics: Adenocarcinoma; Androgens; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Survival; Chlord

2000
[A case of prostate cancer treated with combined androgen-blockade].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:2

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents; Diethylstilbestrol; Flutamide; Humans;

2000
A pilot study of intermittent androgen ablation in advanced prostate cancer in Japanese men.
    Japanese journal of clinical oncology, 2000, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Alkaline Phosphatase; Androgen Antagonists; Antineoplastic

2000
Minimally invasive treatment for localized adenocarcinoma of the prostate: review of 1048 patients treated with ultrasound-guided palladium-103 brachytherapy.
    Journal of endourology, 2000, Volume: 14, Issue:4

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Biop

2000
Efficacious chemoprevention of primary prostate cancer by flutamide in an autochthonous transgenic model.
    Cancer research, 2000, Aug-01, Volume: 60, Issue:15

    Topics: Adenocarcinoma; Androgen Antagonists; Animals; Anticarcinogenic Agents; Blotting, Western; Crosses,

2000
Metastatic, sarcomatoid, and PSA- and PAP-negative prostatic carcinoma: diagnosis by fine-needle aspiration.
    Diagnostic cytopathology, 2000, Volume: 23, Issue:3

    Topics: Acid Phosphatase; Adenocarcinoma; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemother

2000
Macrophage migration inhibitory factor in prostatic adenocarcinoma: correlation with tumor grading and combination endocrine treatment-related changes.
    The Prostate, 2000, Sep-15, Volume: 45, Issue:1

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Androgens; Antineoplastic Agents, Hormonal; Antineoplast

2000
[Fulminant liver failure induced by flutamide].
    Revista espanola de enfermedades digestivas, 2000, Volume: 92, Issue:6

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Flutamide; Humans; Liver Failure; Male; Prostatic Neopla

2000
Update on Memorial Sloan-Kettering Cancer Center studies of neoadjuvant hormonal therapy for prostate cancer.
    Molecular urology, 2000,Fall, Volume: 4, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Hormonal; Biopsy; Clinical Trials, Phase II as T

2000
[Adenoid cystic carcinoma of the prostate. Clinical case].
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2000, Volume: 52, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Biopsy; Carcinoma, Adenoid Cysti

2000
Neoadjuvant hormone therapy and radical radiotherapy for localized prostate cancer: poorer biochemical outcome using flutamide alone.
    The Canadian journal of urology, 2000, Volume: 7, Issue:5

    Topics: Adenocarcinoma; Androgen Antagonists; Antineoplastic Agents, Hormonal; Chi-Square Distribution; Flut

2000
Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Animals; Binding Sites; Cell Line; COS Cells; Dihyd

2001
Characterization of androgen receptors in a well-differentiated endometrial adenocarcinoma cell line (Ishikawa).
    The Journal of steroid biochemistry and molecular biology, 2000, Nov-15, Volume: 74, Issue:4

    Topics: Adenocarcinoma; Alkaline Phosphatase; Androgens; Cell Differentiation; Cell Nucleus; Diethylstilbest

2000
Prostate cancer with multiple lung metastases in a hemodialysis patient.
    International journal of urology : official journal of the Japanese Urological Association, 2000, Volume: 7, Issue:12

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Drug Therapy, Combinati

2000
Hormonal regulation of appetite and body mass in patients with advanced prostate cancer treated with combined androgen blockade.
    Journal of endocrinological investigation, 2001, Volume: 24, Issue:1

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Appetite

2001
Chemical andropause and amyloid-beta peptide.
    JAMA, 2001, May-02, Volume: 285, Issue:17

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Androgen Antagoni

2001
Oncogenic osteomalacia.
    The Israel Medical Association journal : IMAJ, 2000, Volume: 2, Issue:12

    Topics: Adenocarcinoma; Aged; Bone Neoplasms; Cholecalciferol; Disease Progression; Fatal Outcome; Flutamide

2000
Flutamide-induced acute hepatitis in advanced prostate cancer patients.
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:9

    Topics: Adenocarcinoma; Administration, Oral; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; C

2001
Experience with flutamide in previously untreated patients with advanced prostatic cancer.
    The Journal of urology, 1979, Volume: 122, Issue:5

    Topics: Adenocarcinoma; Aged; Anilides; Flutamide; Humans; Male; Middle Aged; Prostatic Neoplasms

1979
Idiopathic resistance to luteinizing hormone-releasing hormone analogue in a patient with prostatic carcinoma.
    The Journal of urology, 1992, Volume: 148, Issue:5

    Topics: Adenocarcinoma; Aged; Drug Resistance; Flutamide; Follicle Stimulating Hormone; Goserelin; Humans; L

1992
Incidence of liver toxicity associated with the use of flutamide in prostate cancer patients.
    The American journal of medicine, 1992, Volume: 92, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Alkaline Phosphatase; Androgen

1992
Objective treatment response to endocrine therapy in metastatic prostate cancer.
    Urology, 1992, Volume: 40, Issue:5

    Topics: Adenocarcinoma; Bone Neoplasms; Combined Modality Therapy; Estrogens; Flutamide; Humans; Lymphatic M

1992
Transrectal ultrasound evaluation of local prostate cancer in patients treated with LHRH agonist and in combination with flutamide.
    Urology, 1992, Volume: 39, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Drug Therapy, Combination; Flutamide; Gonadotropin-Releasin

1992
Effect of combination endocrine therapy (LHRH agonist and flutamide) on normal prostate and prostatic adenocarcinoma. A histopathologic and immunohistochemical study.
    The American journal of surgical pathology, 1991, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Drug Therapy, Combination; Flutamide; Gonadotropin-Releasing Hormone; Humans; Immuno

1991
Long-term experience with flutamide in patients with prostatic carcinoma.
    Urology, 1989, Volume: 34, Issue:4 Suppl

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anilides; Diethylstilbestrol; Flutamide; Humans; Male; Midd

1989
[Combined anti-androgen treatment in adenocarcinoma of the prostate: first use of a new therapeutically efficacious principle in hormone-dependent cancer].
    Annales d'urologie, 1986, Volume: 20, Issue:2

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents; Drug Therapy, Combination; Flutam

1986
Combination therapy with flutamide and castration (orchiectomy or LHRH agonist): the minimal endocrine therapy in both untreated and previously treated patients.
    Journal of steroid biochemistry, 1987, Volume: 27, Issue:1-3

    Topics: Adenocarcinoma; Androgens; Anilides; Combined Modality Therapy; Evaluation Studies as Topic; Flutami

1987
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1988, Volume: 11, Issue:5

    Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Androstane-3,17-diol; Androstenediol; Androstene

1988
Effect of adrenalectomy, flutamide, and leuprolide on the growth of the Dunning rat R-3327 prostatic carcinoma.
    The Prostate, 1988, Volume: 12, Issue:4

    Topics: Adenocarcinoma; Adrenalectomy; Anilides; Animals; Antineoplastic Agents; Antineoplastic Combined Che

1988
Combination therapy with flutamide and [D-Trp6]LHRH ethylamide for stage C prostatic carcinoma.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:4

    Topics: Acid Phosphatase; Adenocarcinoma; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Antineoplastic C

1988
Flutamide--an antiandrogen inhibiting prostatic cancer and prostatic secretion with retention of potency.
    Medical oncology and tumor pharmacotherapy, 1988, Volume: 5, Issue:1

    Topics: Adenocarcinoma; Aged; Anilides; Fertility; Flutamide; Humans; Male; Middle Aged; Prostate; Prostatic

1988
Loss of luteinizing hormone bioactivity in patients with prostatic cancer treated with an LHRH agonist and a pure antiandrogen.
    Clinical endocrinology, 1986, Volume: 24, Issue:1

    Topics: Adenocarcinoma; Anilides; Animals; Biological Assay; Drug Therapy, Combination; Flutamide; Gonadotro

1986
A new antiprostatic agent for treatment of prostatic carcinoma.
    Surgical forum, 1973, Volume: 24

    Topics: Adenocarcinoma; Anilides; Flutamide; Gynecomastia; Humans; Male; Neoplasm Metastasis; Prostatic Neop

1973